Journal ArticleJ Neurosurg Case Lessons · May 5, 2025
BACKGROUND: Idiopathic intracranial hypertension (IIH) and venous sinus stenosis have recently been implicated in the pathogenesis of encephaloceles. OBSERVATIONS: Here, the authors present 2 cases in which venous sinus stenting was crucial for symptom man ...
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Journal ArticleInterv Neuroradiol · April 24, 2025
BackgroundVenous hypertension has become a recognized condition associated with idiopathic intracranial hypertension (IIH). Thresholds for dural venous sinus stenting (VSS) remain a topic of debate.MethodsIn 50 IIH patients, the lumbar puncture opening pre ...
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Journal ArticleInterv Neuroradiol · March 26, 2025
ObjectiveIntra-arterial chemotherapy (IAC) is a well-established treatment for retinoblastoma (RB). However, there are no standardized recommendations regarding the choice of drugs. This study compares the outcomes of single- versus multi-drug therapy.Meth ...
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Journal ArticleJ Neurointerv Surg · January 26, 2025
BACKGROUND: Idiopathic intracranial hypertension (IIH) is a complex neurological condition characterized by symptoms of increased intracranial pressure of unclear etiology. While transverse sinus stenosis (TSS) is often present in patients with IIH, how an ...
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Journal ArticleJ Neurosurg Case Lessons · April 29, 2024
BACKGROUND: Early venous drainage is a critical diagnostic feature of arteriovenous malformations (AVMs) and arteriovenous fistulas (AVFs). However, other conditions associated with early venous drainage can mimic AVMs and AVFs and mislead the treating phy ...
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Journal ArticleJ Neurosurg Case Lessons · June 12, 2023
BACKGROUND: Vein of Galen malformations (VoGMs) in newborns often represent life-threatening emergencies. Outcome is difficult to predict. The authors review 50 VoGM cases to correlate anatomical types with treatment and outcome. OBSERVATIONS: Four distinc ...
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Journal ArticleJ Neurosurg Case Lessons · October 10, 2022
BACKGROUND: Successful management of a vein of Galen malformation (VoGM) in the newborn patient requires a highly coordinated team approach involving neonatologists, pediatric cardiologists, pediatric neurologists, neurosurgeons, and interventionalists. In ...
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Journal ArticleJ Neurosurg · May 1, 2022
OBJECTIVE: Indication for surgery in brainstem cavernous malformations (BSCMs) is based on many case series, few comparative studies, and no randomized controlled trials. The objective of this study was to seek consensus about surgical management aspects o ...
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Journal ArticleBMJ Case Rep · March 4, 2022
An 18-year-old woman with a history of Down syndrome (DS) presented with left upper extremity weakness. Neurological examination revealed moderate hypotonia throughout, with mild spasticity of the left ankle. She had 2/5 left upper and lower extremity stre ...
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Journal ArticleCureus · January 2022
Proximal Hunterian ligation remains a treatment option for select complex brain aneurysms. Progressive occlusion over time (as accomplished with Selverstone clamping) can enable collateral flow to develop while the aneurysm regresses or occludes. A 50-year ...
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Journal ArticleNeurosurg Rev · June 2021
Fusiform aneurysms are less common than saccular aneurysms, but have higher associated mortality and rebleeding rates. Recently, flow diversion has emerged as a possible treatment option. The purpose of this study was to determine the safety and efficacy o ...
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Journal ArticleClinical neurology and neurosurgery · December 2020
ObjectiveDecompressive craniectomy (DC) is a standard neurosurgical procedure against intractable intracranial hypertension. Patients with severe aneurysmal subarachnoid hemorrhage (aSAH) are prone to intracranial hypertension, necessitating DC in ...
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Journal ArticleJ Magn Reson Imaging · August 2020
BACKGROUND: The translation of phase-resolved functional lung (PREFUL)-MRI to routine practice in monitoring chronic thromboembolic pulmonary hypertension (CTEPH) still requires clinical corresponding imaging biomarkers of pulmonary vascular disease. PURPO ...
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Journal ArticleEur J Radiol · April 2020
PURPOSE: To determine the clinical impact of CT dose management team on radiation exposure and image quality. METHODS: 2026 clinical routine CT examinations of 1315 patients were evaluated retrospectively. A CT dose management team was established as an in ...
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Journal ArticleNeurosurg Rev · February 2020
Paramedian thalamic strokes following occlusion of the posterior medial (paramedian) thalamic perforators have been previously described in great detail. However, the stroke syndrome associated with occlusion of posterior lateral (inferolateral) thalamic p ...
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Journal ArticleWorld Neurosurg · October 2019
BACKGROUND: Flow-diverting stents have revolutionized the endovascular treatment of intracranial aneurysms. The purpose of this study is to identify predictors of adverse outcomes associated with the pipeline embolization device (PED). METHODS: A retrospec ...
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Journal ArticleStroke · September 2019
Background and Purpose- The PILLAR (Extracorporeal Filtration of Subarachnoid Hemorrhage via Spinal Catheter) study is a first-in-human trial of cerebrospinal fluid (CSF) filtration in aneurysmal subarachnoid hemorrhage. The study evaluates the safety and ...
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Journal ArticleInterv Neuroradiol · April 2019
Direct carotid-cavernous fistulas (CCFs) are high flow lesions that can be challenging to treat. A number of recent reports suggest that flow diversion may be a viable treatment option. We present a case of a post-traumatic CCF successfully treated with fl ...
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Journal ArticleWorld Neurosurg · March 2019
BACKGROUND: Infundibular dilations are funnel-shaped widenings at the origin of a cerebral artery, most commonly the posterior communicating artery. Controversy exists as to whether an infundibulum represents a normal anatomic variant or a lesion with the ...
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Journal ArticleWorld Neurosurg · February 2019
BACKGROUND: Thromboembolic complications are serious adverse events associated with stenting of intracranial aneurysms. For the development of novel devices, currently no practical model exists to evaluate distal embolic events. The purpose of the current ...
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Journal ArticleInterv Neuroradiol · February 2019
A 48-year-old woman presented with an acute ischemic stroke (National Institutes of Health Stroke Scale (NIHSS) 21) six hours after symptom onset. Workup revealed a left cervical internal carotid artery (ICA) occlusive dissection, which was emergently reco ...
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Journal ArticleInterv Neuroradiol · December 2018
BACKGROUND AND IMPORTANCE: Pial arteriovenous fistulas (AVFs) of the brain are treacherous lesions that can be challenging to treat because of high risk of hemorrhage. We report on a rare case of a pial AVF with a giant venous varix as a draining vein trea ...
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Journal ArticleChilds Nerv Syst · April 2017
BACKGROUND: Various strategies are emerging for dosing antiplatelet therapies in preparation for pipeline stent embolization in adults. Hyper-response is associated with hemorrhagic complications. Hypo-response is associated with thromboembolic events. Dos ...
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Journal ArticleJ Clin Neurosci · April 2017
INTRO: In light of the recent successful mechanical thrombectomy trials, the need for IV-tPA prior is under investigation. Few cases demonstrate angiographically the role of both mechanical and chemical strategies at achieving reperfusion. CASE REPORT: A 6 ...
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Journal ArticleNeurosurgery · September 2013
BACKGROUND AND IMPORTANCE: Flow diversion with the pipeline embolization device (PED) is an emerging endovascular technology allowing curative embolization of very large and giant intracranial aneurysms. Many patients with these complex aneurysms are older ...
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Journal ArticleAJNR Am J Neuroradiol · October 2012
The Outreach DAC is an intermediate-sized catheter designed for use with the Merci clot retriever in acute stroke. We investigated its utility as an adjunctive device during AVM pedicle embolization. In the authors' opinion, the DAC provided additional gui ...
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Journal ArticleJ Neurointerv Surg · December 1, 2011
PURPOSE: The authors report the endovascular treatment of intracranial stenosis in six patients with moyamoya-type collaterals. PATIENTS: All patients previously had experienced a stroke or transient ischemic attack. Lesion locations included a unilateral ...
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Journal ArticleNeurosurgery · October 2011
BACKGROUND: Acute proximal (cervical) internal carotid artery (ICA) occlusion may cause ischemia of an entire hemisphere or no ischemia at all, depending on the presence of intracranial collaterals. OBJECTIVE: To retrospectively analyze the clinical result ...
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Journal ArticleJ Neurosurg · July 2011
OBJECT: The objective of this study was to evaluate endovascular stent therapy for carotid artery dissections (CADs). METHODS: Retrospective review of data at Millard Fillmore Gates Hospital identified 43 patients with 44 CADs (intracranial and/or extracra ...
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Journal ArticleNeurosurgery · July 2011
BACKGROUND AND IMPORTANCE: This article describes delayed endovascular revascularization in a patient with clinical and radiographic evidence of posterior circulation hemodynamic failure in the setting of intracranial occlusive lesions. CLINICAL PRESENTATI ...
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Journal ArticleJ Neurointerv Surg · June 2011
OBJECTIVE: The Outreach distal access catheter (DAC; Concentric Medical, Mountain View, California, USA) has been designed to assist the Merci device (Concentric Medical) with clot retrieval in the setting of acute stroke. Its application for coil emboliza ...
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Journal ArticleJ Neurointerv Surg · March 2011
An individual in their 30s presented with quadriplegia and coma 7 h after a 30-foot free-fall. Angiography confirmed left vertebral artery dissection causing vertebral artery occlusion (thrombolysis in myocardial infarction (TIMI) 0) and basilar artery thr ...
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Journal ArticleJ Neurointerv Surg · March 2011
We report a case of aneurysm progression after waffle-cone treatment. A patient in their seventies presented with headaches. Four years earlier, this individual had undergone waffle-cone treatment of a giant ruptured left ophthalmic aneurysm. Angiography d ...
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Journal ArticleJ Clin Neurosci · March 2011
The authors present a preliminary experience with ethyl-enevinylalcohol copolymer (Onyx) for hemangioblastoma vessel embolization before surgical resection. The patient presented with neck pain, dizziness, blurred vision, vomiting, and loss of balance. Dia ...
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Journal ArticleJ Neurosurg · January 2011
OBJECT: In this paper, the authors' goal was to report the outcome of patients with unruptured intracranial aneurysms undergoing endovascular treatment under conscious sedation (local anesthesia). METHODS: Between November 5, 2001, and February 5, 2009, th ...
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Journal ArticleJ Neurointerv Surg · December 2010
A novel technique is reported that helps the operator in achieving reliable access to the distal parent vessel with a microcatheter for stent assisted aneurysm coiling. Distal parent vessel access was obtained by allowing the microwire to follow the local ...
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Journal ArticleNeurosurgery · December 2010
BACKGROUND AND IMPORTANCE: The Pipeline embolization device (PED; Covidien Vascular Therapies, Mansfield, Massachusetts) is a promising, yet experimental, vascular reconstruction device for the treatment of complex intracranial aneurysms. We present a PED- ...
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Journal ArticleNeurosurgery · October 2010
BACKGROUND AND IMPORTANCE: Patients with chronic carotid artery occlusion face a significant risk of stroke. It is believed that treatment is indicated if medical therapy fails or even as prophylaxis in high-risk patients. Direct surgical repair with carot ...
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Journal ArticleJ Neurosurg · October 2010
OBJECT: Anterolateral cavernomas of the pons have been surgically removed via a variety of approaches, commonly retrosigmoid or transventricular. The goal in this study was to evaluate the presigmoid approach as an alternative. METHODS: Clinical data were ...
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Journal ArticleNeurosurgery · September 2010
BACKGROUND: The benefits of intravenous thrombolysis for acute ischemic stroke are still limited. OBJECTIVE: To evaluate the safety and efficacy of double-lumen balloon catheter-based reperfusion therapy with or without intra-arterial thrombolysis for acut ...
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Journal ArticleNeurosurgery · September 2010
OBJECTIVE: To describe the technique of endovascular access for treatment of vasospasm of a radial artery bypass graft from the occipital artery to the M3 branch of the middle cerebral artery (MCA) in a patient with moyamoya disease. CLINICAL PRESENTATION: ...
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Journal ArticleNeurosurgery · September 2010
OBJECTIVE: Endovascular treatment of large intracranial aneurysms arising from a fenestrated parent vessel may prove particularly difficult. We present a case of a large, broad-based aneurysm arising from a proximal basilar artery (BA) fenestration treated ...
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Journal ArticleJ Neurosurg · June 2010
OBJECT: Because the risks are reduced, larger basilar apex aneurysms are usually treated endovascularly instead of with surgery. However, small basilar apex aneurysms are more common and an unfavorable shape may prevent definitive endovascular treatment. T ...
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Journal ArticleStroke · May 2010
BACKGROUND AND PURPOSE: The prediction of intracranial aneurysm (IA) rupture risk has generated significant controversy. The findings of the International Study of Unruptured Intracranial Aneurysms (ISUIA) that small anterior circulation aneurysms (<7 mm) ...
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Journal ArticleJ Clin Neurosci · May 2010
Catheter-based intra-arterial digital subtraction angiography (IADSA) is widely trusted for diagnosing cerebral aneurysms. However, three-dimensional CT angiography (3D-CTA) is evolving. This study compares the diagnostic performance and inter-rater reliab ...
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Journal ArticleJ Invasive Cardiol · March 2010
OBJECTIVES: To compare our experience with sirolimus and paclitaxel-eluting stents (drug-eluting stents [DES]) and non-drug-eluting stents (NDES) for treatment of vertebral artery (VA) origin stenosis and review the literature. METHODS: A retrospective rev ...
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Journal ArticleJ Neurosurg · March 2010
OBJECT: Acute revascularization has been associated with improved stroke outcomes. The Prolyse in Acute Cerebral Thromboembolism (PROACT II) trial achieved recanalization rates of 66%. The Multi Mechanical Embolus Removal in Cerebral Ischemia (Multi MERCI) ...
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Journal ArticleWorld Neurosurg · 2010
OBJECTIVE: To report results of endovascular therapy for acute ischemic stroke (AIS) in patients who were not candidates for intravenous thrombolysis (IVT) or in whom IVT failed. METHODS: Prospectively collected data for patients treated between January 20 ...
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Journal ArticleStroke · November 2009
BACKGROUND AND PURPOSE: Acute revascularization is associated with improved outcomes in ischemic stroke patients. However, it is unclear which method of intraarterial intervention, if any, is ideal. Numerous case series and cardiac literature parallels sug ...
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Journal ArticleJ Neurosurg Spine · September 2009
OBJECT: The study aims to analyze nerve fiber types in the sacral nerve roots as a prerequisite for stimulation. METHODS: One-micrometer cross-sections of human ventral and dorsal S1-5 roots were stained with osmium and toluidine blue. The total fiber diam ...
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Journal ArticleAJNR Am J Neuroradiol · September 2009
Intracranial stent placement is emerging as an effective treatment for acute stroke. As a means to avoid stent-associated complications and capitalize on stent-placement-related advantages, the concept of a "temporary endovascular bypass" (TEB) for stroke ...
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Journal ArticleSurg Neurol · May 2009
BACKGROUND: Although various bypass options for the surgical treatment of middle cerebral artery aneurysms have been described, little has been reported about similar options for complex aneurysms of the anterior cerebral artery. CASE DESCRIPTION: We repor ...
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Journal ArticleAJNR Am J Neuroradiol · March 2009
BACKGROUND AND PURPOSE: Preoperative embolization facilitates the surgical management of complex cerebral arteriovenous malformations (cAVMs). This analysis aims to investigate the risks for preoperative cAVM embolization with Onyx. MATERIALS AND METHODS: ...
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Journal ArticleNeurosurgery · January 2009
OBJECTIVE: The goal of this study was to analyze the natural history of symptomatic brainstem cavernomas (medulla, pons, or midbrain) and outcome after surgical resection. METHODS: We retrospectively analyzed clinical data of all patients who presented to ...
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Journal ArticleSurg Neurol · January 2009
BACKGROUND: Treatment of VLGUIA remains a challenge. To reduce mass effect and achieve complete occlusion, open surgery has been our favored treatment. However, endovascular therapy is preferred for lesions in the cavernous sinus or for older patients with ...
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Journal ArticleJ Neurosurg · December 2008
OBJECT: Patients with very large or giant unruptured intracranial aneurysms present with ischemic stroke and progressive disability. The aneurysm rupture risk in these patients is extreme-up to 50% in 5 years. In this study the authors investigated the out ...
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Journal ArticleJ Neurosurg · December 2008
OBJECT: Clipping of complex cerebral aneurysms often requires temporary vessel occlusion. The risk of stroke, however, increases exponentially with occlusion time. The authors hypothesized that prolonged temporary occlusion might be tolerated if the occlud ...
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Journal ArticleJ Clin Neurosci · November 2008
Gangliogliomas are mixed tumors consisting of both glial elements and differentiated neurons. Although any part of the central nervous system can be affected, little is known about intraventricular gangliogliomas. A patient with a ganglioglioma is presente ...
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Journal ArticleJ Clin Neurosci · September 2008
The incidence of cerebral phaeohyphomycosis, an infection caused by a dark-pigmented fungus, is increasing. The infection may mimic a high-grade glioma clinically and radiographically. Magnetic resonance spectroscopy may be helpful in differentiating the t ...
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Journal ArticleJ Neurosurg Spine · August 2008
OBJECT: The conus medullaris and the nerve roots from S-1 to S-5 regulate bladder function as well as movement and sensation of the lower extremities. This most caudal region of the spinal cord has not been studied in great detail anatomically despite its ...
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Journal ArticleBrain Res · July 9, 2007
UNLABELLED: Leukocytes contribute to the ischemia-reperfusion injury. Recent studies suggested endothelins could be important mediators for leukocyte activation in stroke. We tested if the endothelinA receptor antagonist BSF-208075 (ambrisentan) could redu ...
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Journal ArticleSurg Neurol · August 2006
BACKGROUND: NF-1 is one of the most common autosomal-dominantly inherited genetic disorders with an incidence of approximately 1:3500. We report a case and review the literature to characterize spontaneous spinal AVF that occur in neurofibromatosis (NF-1). ...
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Journal ArticleJ Craniofac Surg · May 2006
We report a case of locally advanced granular cell tumor of the orbit treated by a multidisciplinary surgical approach. A 49-year-old woman with a recently biopsied granular cell tumor of the orbit was referred to our tertiary care cancer center for evalua ...
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Journal ArticleJ Cereb Blood Flow Metab · April 2004
The reaction of cerebral capillaries to ischemia is unclear. Based on Hossmann's observation of postischemic "delayed hypoperfusion," we hypothesized that capillary flow is decreased during reperfusion because of increased precapillary flow resistance. To ...
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