Overview
Director, Proteomics and Metabolomics Core Facility
Current Appointments & Affiliations
Associate Research Professor of Cell Biology
·
2023 - Present
Cell Biology,
Basic Science Departments
Recent Publications
Regulation of organic anion transporting polypeptide 1B1 transport function by concurrent phosphorylation and lysine-acetylation: A novel posttranslational regulation mechanism
Journal Article Molecular Pharmacology · February 1, 2025 Organic anion transporting polypeptide (OATP) 1B1 is crucial for hepatic uptake of many drugs and endogenous substrates. The clinically relevant OATP1B1 c.521 T>C (V174A) polymorphism exhibits reduced transport activity in vitro and in vivo in humans. Prev ... Full text CitePlasma extracellular vesicles carry immune system-related peptides that predict human longevity.
Journal Article Geroscience · December 18, 2024 Extracellular vesicles (EVs) play crucial roles in aging. In this National Institutes on Aging-funded study, we sought to identify circulating extracellular vesicle (EV) biomarkers indicative of longevity. The plasma EV proteome of 48 older adults (mean ag ... Full text Link to item CiteImmune System-Related Plasma Pathogenic Extracellular Vesicle Subpopulations Predict Osteoarthritis Progression.
Journal Article Int J Mol Sci · November 21, 2024 Certain molecules found on the surface or within the cargo of extracellular vesicles (EVs) are linked to osteoarthritis (OA) severity and progression. We aimed to identify plasma pathogenic EV subpopulations that can predict knee radiographic OA (rOA) prog ... Full text Link to item CiteRecent Grants
Roles for desmsomes in mRNA localization and translational regulation
ResearchCollaborator · Awarded by National Institutes of Health · 2024 - 2029Calcineurin Control over Aspergillus fumigatus Antifungal Response Mechanisms
ResearchCo Investigator · Awarded by Arkansas Children's Research Institute · 2024 - 2029Drug Development for Dystonia
ResearchCo Investigator · Awarded by Department of Defense · 2023 - 2027View All Grants
Education, Training & Certifications
North Carolina State University ·
2008
Ph.D.