Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Ph.D., North Carolina State University 2008
• 

  Previous Appointments & Affiliations

  • Assistant Research Professor of Cell Biology, Cell Biology, Basic Science Departments 2015 - 2023
• Research
• 

  Selected Grants

  • Drug Development for Dystonia awarded by Department of Defense 2023 - 2027
  • Proteomic and Functional Analysis of Presynaptic Physiology and Plasticity awarded by National Institutes of Health 2021 - 2026
  • Gender and APOE genotype interact to alter immune regulated metabolism in AD awarded by National Institutes of Health 2019 - 2024
  • Project #1 awarded by Incyclix Bio, LLC 2022 - 2023
  • Elucidating the postsynaptic interactome of the high risk autism gene ANK2 awarded by University of Pennsylvania 2022 - 2023
  • Mass Spectrometry based characterization of recombinantly expressed proteins awarded by Ribometrix, Inc. 2022 - 2023
  • Developing Novel Medicines to Treat Dystonia awarded by Department of Defense 2019 - 2023
  • Analysis of Inhibitory Synaptic Proteins Associated with Brain Disorders awarded by National Institutes of Health 2017 - 2023
  • Elucidating the postsynaptic interactome of the high risk autism gene ANK2 awarded by University of North Carolina - Chapel Hill 2022
  • Calcineurin regulatory network control of Aspergillus fumigatus hyphal septation awarded by Arkansas Children's Hospital Research Institute 2022
  • Calcineurin regulatory network control of Aspergillus fumigatus hyphal septation awarded by National Institutes of Health 2021 - 2022
  • New Proteomic and Genome Engineering Approaches to Decipher Astrocyte Function at Synapses awarded by National Institutes of Health 2018 - 2021
  • Characterization of NYP Peptides in Prostate Cancer awarded by National Institutes of Health 2019 - 2021
  • Qualification of Prognostic and Diagnostic Biomarkers of Knee Osteoarthritis awarded by National Institutes of Health 2017 - 2021
  • Phosphoproteomic identification of Aspergillus fumigatus virulence-associated protein kinase A downstream effectors awarded by National Institutes of Health 2018 - 2020
  • Defining the Aspergillus fumigatus Calcineurin-Dependent Regulatory Network through Whole Phosphoproteome Analysis awarded by National Institutes of Health 2016 - 2019
  • Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer awarded by National Institutes of Health 2018 - 2019
  • Gender and APOE genotype interact to alter immune regulated metabolism in AD awarded by National Institutes of Health 2017 - 2019
  • Instrumentation for Quantitative Phosphoproteomics and Acetylomics awarded by National Institutes of Health 2014 - 2015
  • Expansion of Capacity for Quantitative and Qualitative Differential Expression - Acquisition of an Integrated System for Nanoscale Capillary LC/MS/MS Analysis Using a UPLC/NanoMate/Q-Tof with On-line and Off-line Data Acquisition Capabilities awarded by National Institutes of Health 2010 - 2011
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Maddala, Rupalatha, Camelia Eldawy, William Bachman, Erik J. Soderblom, and Ponugoti V. Rao. “Glypican-4 regulated actin cytoskeletal reorganization in glucocorticoid treated trabecular meshwork cells and involvement of Wnt/PCP signaling.” J Cell Physiol 238, no. 3 (March 2023): 631–46. https://doi.org/10.1002/jcp.30953.
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    • Zhou, Kaile, Yi-Ju Li, Erik J. Soderblom, Alexander Reed, Vaibhav Jain, Shuming Sun, M Arthur Moseley, and Virginia Byers Kraus. “A "best-in-class" systemic biomarker predictor of clinically relevant knee osteoarthritis structural and pain progression.” Sci Adv 9, no. 4 (January 25, 2023): eabq5095. https://doi.org/10.1126/sciadv.abq5095.
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    • Wu, Jieyu, Liuyang Wang, John F. Ervin, Shih-Hsiu J. Wang, Erik Soderblom, Dennis Ko, and Dong Yan. “GABA signaling triggered by TMC-1/Tmc delays neuronal aging by inhibiting the PKC pathway in C. elegans.” Sci Adv 8, no. 51 (December 21, 2022): eadc9236. https://doi.org/10.1126/sciadv.adc9236.
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    • Shwab, E Keats, Praveen R. Juvvadi, Shareef K. Shaheen, John Allen, Greg Waitt, Erik J. Soderblom, Yohannes G. Asfaw, M Arthur Moseley, and William J. Steinbach. “Protein Kinase A Regulates Autophagy-Associated Proteins Impacting Growth and Virulence of Aspergillus fumigatus.” J Fungi (Basel) 8, no. 4 (March 30, 2022). https://doi.org/10.3390/jof8040354.
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    • Shroff, Kunal, Zachary F. Caffall, Erik J. Soderblom, Greg Waitt, Tricia Ho, and Nicole Calakos. “Dataset on the mass spectrometry-based proteomic profiling of mouse embryonic fibroblasts from a wild type and DYT-TOR1A mouse model of dystonia, basally and during stress.” Data Brief 39 (December 2021): 107609. https://doi.org/10.1016/j.dib.2021.107609.
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    • Erata, Eda, Yudong Gao, Alicia M. Purkey, Erik J. Soderblom, James O. McNamara, and Scott H. Soderling. “Cnksr2 Loss in Mice Leads to Increased Neural Activity and Behavioral Phenotypes of Epilepsy-Aphasia Syndrome.” J Neurosci 41, no. 46 (November 17, 2021): 9633–49. https://doi.org/10.1523/JNEUROSCI.0650-21.2021.
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    • Kannangara, Ashari R., Daniel M. Poole, Colten M. McEwan, Joshua C. Youngs, Vajira K. Weerasekara, Alex M. Thornock, Misael T. Lazaro, et al. “BioID reveals an ATG9A interaction with ATG13-ATG101 in the degradation of p62/SQSTM1-ubiquitin clusters.” Embo Rep 22, no. 10 (October 5, 2021): e51136. https://doi.org/10.15252/embr.202051136.
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    • Chan, Tsz-Yin, Christina M. Egbert, Julia E. Maxson, Adam Siddiqui, Logan J. Larsen, Kristina Kohler, Eranga Roshan Balasooriya, et al. “TNK1 is a ubiquitin-binding and 14-3-3-regulated kinase that can be targeted to block tumor growth.” Nat Commun 12, no. 1 (September 9, 2021): 5337. https://doi.org/10.1038/s41467-021-25622-3.
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    • O’Neil, Shataakshi Dube, Bence Rácz, Walter Evan Brown, Yudong Gao, Erik J. Soderblom, Ryohei Yasuda, and Scott H. Soderling. “Action potential-coupled Rho GTPase signaling drives presynaptic plasticity.” Elife 10 (July 16, 2021). https://doi.org/10.7554/eLife.63756.
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    • Courtland, Jamie L., Tyler Wa Bradshaw, Greg Waitt, Erik J. Soderblom, Tricia Ho, Anna Rajab, Ricardo Vancini, Il Hwan Kim, and Scott H. Soderling. “Genetic disruption of WASHC4 drives endo-lysosomal dysfunction and cognitive-movement impairments in mice and humans.” Elife 10 (March 22, 2021). https://doi.org/10.7554/eLife.61590.
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    • Shwab, E Keats, Praveen R. Juvvadi, Greg Waitt, Shareef Shaheen, John Allen, Erik J. Soderblom, Benjamin G. Bobay, Yohannes G. Asfaw, M Arthur Moseley, and William J. Steinbach. “The Protein Kinase A-Dependent Phosphoproteome of the Human Pathogen Aspergillus fumigatus Reveals Diverse Virulence-Associated Kinase Targets.” Mbio 11, no. 6 (December 15, 2020). https://doi.org/10.1128/mBio.02880-20.
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    • Takano, Tetsuya, John T. Wallace, Katherine T. Baldwin, Alicia M. Purkey, Akiyoshi Uezu, Jamie L. Courtland, Erik J. Soderblom, et al. “Chemico-genetic discovery of astrocytic control of inhibition in vivo.” Nature 588, no. 7837 (December 2020): 296–302. https://doi.org/10.1038/s41586-020-2926-0.
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    • Rao, Sneha R., Jason A. Somarelli, Erdem Altunel, Laura E. Selmic, Mark Byrum, Maya U. Sheth, Serene Cheng, et al. “From the Clinic to the Bench and Back Again in One Dog Year: How a Cross-Species Pipeline to Identify New Treatments for Sarcoma Illuminates the Path Forward in Precision Medicine.” Front Oncol 10 (2020): 117. https://doi.org/10.3389/fonc.2020.00117.
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    • Bartkowiak, Bartlomiej, Christopher M. Yan, Erik J. Soderblom, and Arno L. Greenleaf. “CDK12 Activity-Dependent Phosphorylation Events in Human Cells.” Biomolecules 9, no. 10 (October 22, 2019). https://doi.org/10.3390/biom9100634.
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    • Shwab, E Keats, Praveen R. Juvvadi, Greg Waitt, Erik J. Soderblom, Blake C. Barrington, Yohannes G. Asfaw, M Arthur Moseley, and William J. Steinbach. “Calcineurin-dependent dephosphorylation of the transcription factor CrzA at specific sites controls conidiation, stress tolerance, and virulence of Aspergillus fumigatus.” Mol Microbiol 112, no. 1 (July 2019): 62–80. https://doi.org/10.1111/mmi.14254.
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    • Tighe, Robert M., Karissa Heck, Erik Soderblom, Shutang Zhou, Anastasiya Birukova, Kenneth Young, Douglas Rouse, et al. “Immediate Release of Gastrin-Releasing Peptide Mediates Delayed Radiation-Induced Pulmonary Fibrosis.” Am J Pathol 189, no. 5 (May 2019): 1029–40. https://doi.org/10.1016/j.ajpath.2019.01.017.
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    • Spence, Erin F., Shataakshi Dube, Akiyoshi Uezu, Margaret Locke, Erik J. Soderblom, and Scott H. Soderling. “In vivo proximity proteomics of nascent synapses reveals a novel regulator of cytoskeleton-mediated synaptic maturation.” Nat Commun 10, no. 1 (January 23, 2019): 386. https://doi.org/10.1038/s41467-019-08288-w.
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    • Essock-Burns, T., E. J. Soderblom, B. Orihuela, M. Arthur Moseley, and D. Rittschof. “Hypothesis testing with proteomics: A case study using wound healing mechanisms in fluids associated with barnacle glue.” Frontiers in Marine Science 6, no. JUN (January 1, 2019). https://doi.org/10.3389/fmars.2019.00343.
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    • Vi, Linda, Gurpreet S. Baht, Erik J. Soderblom, Heather Whetstone, Qingxia Wei, Bridgette Furman, Vijitha Puviindran, et al. “Macrophage cells secrete factors including LRP1 that orchestrate the rejuvenation of bone repair in mice.” Nat Commun 9, no. 1 (December 5, 2018): 5191. https://doi.org/10.1038/s41467-018-07666-0.
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    • Juvvadi, Praveen R., D Christopher Cole, Katie Falloon, Greg Waitt, Erik J. Soderblom, M Arthur Moseley, and William J. Steinbach. “Kin1 kinase localizes at the hyphal septum and is dephosphorylated by calcineurin but is dispensable for septation and virulence in the human pathogen Aspergillus fumigatus.” Biochem Biophys Res Commun 505, no. 3 (November 2, 2018): 740–46. https://doi.org/10.1016/j.bbrc.2018.09.186.
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    • Kelliher, Christina M., Matthew W. Foster, Francis C. Motta, Anastasia Deckard, Erik J. Soderblom, M Arthur Moseley, and Steven B. Haase. “Layers of regulation of cell-cycle gene expression in the budding yeast Saccharomyces cerevisiae.” Mol Biol Cell 29, no. 22 (November 1, 2018): 2644–55. https://doi.org/10.1091/mbc.E18-04-0255.
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    • Wall, Christine E., Megan Holmes, Erik J. Soderblom, and Andrea B. Taylor. “Proteomics and immunohistochemistry identify the expression of α-cardiac myosin heavy chain in the jaw-closing muscles of sooty mangabeys (order Primates).” Arch Oral Biol 91 (July 2018): 103–8. https://doi.org/10.1016/j.archoralbio.2018.01.019.
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    • Toleman, Clifford A., Maria A. Schumacher, Seok-Ho Yu, Wenjie Zeng, Nathan J. Cox, Timothy J. Smith, Erik J. Soderblom, Amberlyn M. Wands, Jennifer J. Kohler, and Michael Boyce. “Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins.” Proc Natl Acad Sci U S A 115, no. 23 (June 5, 2018): 5956–61. https://doi.org/10.1073/pnas.1722437115.
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    • Bareja, Akshay, Conrad P. Hodgkinson, Erik Soderblom, Greg Waitt, and Victor J. Dzau. “The proximity-labeling technique BioID identifies sorting nexin 6 as a member of the insulin-like growth factor 1 (IGF1)-IGF1 receptor pathway.” J Biol Chem 293, no. 17 (April 27, 2018): 6449–59. https://doi.org/10.1074/jbc.RA118.002406.
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    • Ross, Peter, Paige S. Nemec, Alexander Kapatos, Keith R. Miller, Jennifer C. Holmes, Steven E. Suter, Adam S. Buntzman, Erik J. Soderblom, Edward J. Collins, and Paul R. Hess. “The canine MHC class Ia allele DLA-88*508:01 presents diverse self- and canine distemper virus-origin peptides of varying length that have a conserved binding motif.” Vet Immunol Immunopathol 197 (March 2018): 76–86. https://doi.org/10.1016/j.vetimm.2018.01.005.
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    • Renshaw, Hilary, José M. Vargas-Muñiz, Praveen R. Juvvadi, Amber D. Richards, Greg Waitt, Erik J. Soderblom, M Arthur Moseley, and William J. Steinbach. “The tail domain of the Aspergillus fumigatus class V myosin MyoE orchestrates septal localization and hyphal growth.” J Cell Sci 131, no. 3 (February 7, 2018). https://doi.org/10.1242/jcs.205955.
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    • Juvvadi, Praveen R., M Arthur Moseley, Christopher J. Hughes, Erik J. Soderblom, Sarah Lennon, Simon R. Perkins, J Will Thompson, et al. “Scanning Quadrupole Data-Independent Acquisition, Part B: Application to the Analysis of the Calcineurin-Interacting Proteins during Treatment of Aspergillus fumigatus with Azole and Echinocandin Antifungal Drugs.” J Proteome Res 17, no. 2 (February 2, 2018): 780–93. https://doi.org/10.1021/acs.jproteome.7b00499.
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    • Moseley, M Arthur, Christopher J. Hughes, Praveen R. Juvvadi, Erik J. Soderblom, Sarah Lennon, Simon R. Perkins, J Will Thompson, et al. “Scanning Quadrupole Data-Independent Acquisition, Part A: Qualitative and Quantitative Characterization.” J Proteome Res 17, no. 2 (February 2, 2018): 770–79. https://doi.org/10.1021/acs.jproteome.7b00464.
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    • Cox, Nathan J., Gokhan Unlu, Brittany J. Bisnett, Thomas R. Meister, Brett M. Condon, Peter M. Luo, Timothy J. Smith, et al. “Dynamic Glycosylation Governs the Vertebrate COPII Protein Trafficking Pathway.” Biochemistry 57, no. 1 (January 9, 2018): 91–107. https://doi.org/10.1021/acs.biochem.7b00870.
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    • Cox, Nathan J., Peter M. Luo, Timothy J. Smith, Brittany J. Bisnett, Erik J. Soderblom, and Michael Boyce. “A Novel Glycoproteomics Workflow Reveals Dynamic O-GlcNAcylation of COPγ1 as a Candidate Regulator of Protein Trafficking.” Front Endocrinol (Lausanne) 9 (2018): 606. https://doi.org/10.3389/fendo.2018.00606.
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    • Shwab, Elliot K., Praveen R. Juvvadi, Greg Waitt, Erik J. Soderblom, Martin A. Moseley, Nathan I. Nicely, and William J. Steinbach. “Phosphorylation of Aspergillus fumigatus PkaR impacts growth and cell wall integrity through novel mechanisms.” Febs Lett 591, no. 22 (November 2017): 3730–44. https://doi.org/10.1002/1873-3468.12886.
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    • Banks, Courtney J., Nathan W. Rodriguez, Kyle R. Gashler, Rushika R. Pandya, Jeffrey B. Mortenson, Matthew D. Whited, Erik J. Soderblom, et al. “Acylation of Superoxide Dismutase 1 (SOD1) at K122 Governs SOD1-Mediated Inhibition of Mitochondrial Respiration.” Mol Cell Biol 37, no. 20 (October 15, 2017). https://doi.org/10.1128/MCB.00354-17.
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    • Chen, Po-Han, Timothy J. Smith, Jianli Wu, Priscila F. Siesser, Brittany J. Bisnett, Farhan Khan, Maxwell Hogue, et al. “Glycosylation of KEAP1 links nutrient sensing to redox stress signaling.” Embo J 36, no. 15 (August 1, 2017): 2233–50. https://doi.org/10.15252/embj.201696113.
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    • Wang, Honghui, Steven K. Drake, Chen Yong, Marjan Gucek, Matthew A. Lyes, Avi Z. Rosenberg, Erik Soderblom, M. Arthur Moseley, John P. Dekker, and Anthony F. Suffredini. “A Genoproteomic Approach to Detect Peptide Markers of Bacterial Respiratory Pathogens.” Clin Chem 63, no. 8 (August 2017): 1398–1408. https://doi.org/10.1373/clinchem.2016.269647.
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    • Vargas-Muñiz, José M., Hilary Renshaw, Greg Waitt, Erik J. Soderblom, M Arthur Moseley, Jonathan M. Palmer, Praveen R. Juvvadi, Nancy P. Keller, and William J. Steinbach. “Caspofungin exposure alters the core septin AspB interactome of Aspergillus fumigatus.” Biochem Biophys Res Commun 485, no. 2 (April 1, 2017): 221–26. https://doi.org/10.1016/j.bbrc.2017.02.116.
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    • Ray, Caroline, Erik J. Soderblom, Yushi Bai, F Ivy Carroll, Marc G. Caron, and Larry S. Barak. “Probing the Allosteric Role of the α5 Subunit of α3β4α5 Nicotinic Acetylcholine Receptors by Functionally Selective Modulators and Ligands.” Acs Chem Biol 12, no. 3 (March 17, 2017): 702–14. https://doi.org/10.1021/acschembio.6b01117.
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    • Burke, Thomas W., Ricardo Henao, Erik Soderblom, Ephraim L. Tsalik, J Will Thompson, Micah T. McClain, Marshall Nichols, et al. “Nasopharyngeal Protein Biomarkers of Acute Respiratory Virus Infection.” Ebiomedicine 17 (March 2017): 172–81. https://doi.org/10.1016/j.ebiom.2017.02.015.
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    • Shwab, E Keats, Praveen R. Juvvadi, Greg Waitt, Erik J. Soderblom, M Arthur Moseley, Nathan I. Nicely, Yohannes G. Asfaw, and William J. Steinbach. “A Novel Phosphoregulatory Switch Controls the Activity and Function of the Major Catalytic Subunit of Protein Kinase A in Aspergillus fumigatus.” Mbio 8, no. 1 (February 7, 2017). https://doi.org/10.1128/mBio.02319-16.
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    • Alexander, Georgia M., Yang Zhong Huang, Erik J. Soderblom, Xiao-Ping He, M Arthur Moseley, and James O. McNamara. “Vagal nerve stimulation modifies neuronal activity and the proteome of excitatory synapses of amygdala/piriform cortex.” J Neurochem 140, no. 4 (February 2017): 629–44. https://doi.org/10.1111/jnc.13931.
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    • Uezu, Akiyoshi, Daniel J. Kanak, Tyler W. A. Bradshaw, Erik J. Soderblom, Christina M. Catavero, Alain C. Burette, Richard J. Weinberg, and Scott H. Soderling. “Identification of an elaborate complex mediating postsynaptic inhibition.” Science 353, no. 6304 (September 9, 2016): 1123–29. https://doi.org/10.1126/science.aag0821.
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    • Park, Hee-Soo, Eve W. L. Chow, Ci Fu, Erik J. Soderblom, M Arthur Moseley, Joseph Heitman, and Maria E. Cardenas. “Calcineurin Targets Involved in Stress Survival and Fungal Virulence.” Plos Pathog 12, no. 9 (September 2016): e1005873. https://doi.org/10.1371/journal.ppat.1005873.
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    • Quinones, Quintin J., Zhiquan Zhang, Qing Ma, Michael P. Smith, Erik Soderblom, M Arthur Moseley, James Bain, et al. “Proteomic Profiling Reveals Adaptive Responses to Surgical Myocardial Ischemia-Reperfusion in Hibernating Arctic Ground Squirrels Compared to Rats.” Anesthesiology 124, no. 6 (June 2016): 1296–1310. https://doi.org/10.1097/ALN.0000000000001113.
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    • Michelotti, Gregory A., Anikia Tucker, Marzena Swiderska-Syn, Mariana Verdelho Machado, Steve S. Choi, Leandi Kruger, Erik Soderblom, et al. “Pleiotrophin regulates the ductular reaction by controlling the migration of cells in liver progenitor niches.” Gut 65, no. 4 (April 2016): 683–92. https://doi.org/10.1136/gutjnl-2014-308176.
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    • Phillips, Stacia L., Erik J. Soderblom, Shelton S. Bradrick, and Mariano A. Garcia-Blanco. “Identification of Proteins Bound to Dengue Viral RNA In Vivo Reveals New Host Proteins Important for Virus Replication.” Mbio 7, no. 1 (January 5, 2016): e01865–e01815. https://doi.org/10.1128/mBio.01865-15.
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    • Vargas-Muñiz, José M., Hilary Renshaw, Amber D. Richards, Greg Waitt, Erik J. Soderblom, Martin A. Moseley, Yohannes Asfaw, Praveen R. Juvvadi, and William J. Steinbach. “Dephosphorylation of the Core Septin, AspB, in a Protein Phosphatase 2A-Dependent Manner Impacts Its Localization and Function in the Fungal Pathogen Aspergillus fumigatus.” Front Microbiol 7 (2016): 997. https://doi.org/10.3389/fmicb.2016.00997.
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    • Barrientos, Tomasa, Indira Laothamatas, Timothy R. Koves, Erik J. Soderblom, Miles Bryan, M Arthur Moseley, Deborah M. Muoio, and Nancy C. Andrews. “Metabolic Catastrophe in Mice Lacking Transferrin Receptor in Muscle.” Ebiomedicine 2, no. 11 (November 2015): 1705–17. https://doi.org/10.1016/j.ebiom.2015.09.041.
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    • Juvvadi, Praveen R., Alberto Muñoz, Frédéric Lamoth, Erik J. Soderblom, M Arthur Moseley, Nick D. Read, and William J. Steinbach. “Calcium-Mediated Induction of Paradoxical Growth following Caspofungin Treatment Is Associated with Calcineurin Activation and Phosphorylation in Aspergillus fumigatus.” Antimicrob Agents Chemother 59, no. 8 (August 2015): 4946–55. https://doi.org/10.1128/AAC.00263-15.
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    • Lamoth, Frédéric, Praveen R. Juvvadi, Erik J. Soderblom, M Arthur Moseley, and William J. Steinbach. “Hsp70 and the Cochaperone StiA (Hop) Orchestrate Hsp90-Mediated Caspofungin Tolerance in Aspergillus fumigatus.” Antimicrob Agents Chemother 59, no. 8 (August 2015): 4727–33. https://doi.org/10.1128/AAC.00946-15.
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    • Vargas-Muñiz, José M., Hilary Renshaw, Amber D. Richards, Frédéric Lamoth, Erik J. Soderblom, M Arthur Moseley, Praveen R. Juvvadi, and William J. Steinbach. “The Aspergillus fumigatus septins play pleiotropic roles in septation, conidiation, and cell wall stress, but are dispensable for virulence.” Fungal Genet Biol 81 (August 2015): 41–51. https://doi.org/10.1016/j.fgb.2015.05.014.
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    • Bauernfeind, Amy L., Erik J. Soderblom, Meredith E. Turner, M Arthur Moseley, John J. Ely, Patrick R. Hof, Chet C. Sherwood, Gregory A. Wray, and Courtney C. Babbitt. “Evolutionary Divergence of Gene and Protein Expression in the Brains of Humans and Chimpanzees.” Genome Biol Evol 7, no. 8 (July 10, 2015): 2276–88. https://doi.org/10.1093/gbe/evv132.
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    • Foster, Matthew W., Lake D. Morrison, Jamie L. Todd, Laurie D. Snyder, J Will Thompson, Erik J. Soderblom, Kelly Plonk, et al. “Quantitative proteomics of bronchoalveolar lavage fluid in idiopathic pulmonary fibrosis.” J Proteome Res 14, no. 2 (February 6, 2015): 1238–49. https://doi.org/10.1021/pr501149m.
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    • Juvvadi, Praveen R., Yan Ma, Amber D. Richards, Erik J. Soderblom, M Arthur Moseley, Frédéric Lamoth, and William J. Steinbach. “Identification and mutational analyses of phosphorylation sites of the calcineurin-binding protein CbpA and the identification of domains required for calcineurin binding in Aspergillus fumigatus.” Front Microbiol 6 (2015): 175. https://doi.org/10.3389/fmicb.2015.00175.
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    • Huang, Bofu, Chih-Sheng Yang, Jeffrey Wojton, Nai-Jia Huang, Chen Chen, Erik J. Soderblom, Liguo Zhang, and Sally Kornbluth. “Metabolic control of Ca2+/calmodulin-dependent protein kinase II (CaMKII)-mediated caspase-2 suppression by the B55β/protein phosphatase 2A (PP2A).” J Biol Chem 289, no. 52 (December 26, 2014): 35882–90. https://doi.org/10.1074/jbc.M114.585844.
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    • Pfenning, Andreas R., Erina Hara, Osceola Whitney, Miriam V. Rivas, Rui Wang, Petra L. Roulhac, Jason T. Howard, et al. “Convergent transcriptional specializations in the brains of humans and song-learning birds.” Science 346, no. 6215 (December 12, 2014): 1256846. https://doi.org/10.1126/science.1256846.
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    • Olson, Andrew L., Ashley T. Tucker, Benjamin G. Bobay, Erik J. Soderblom, M Arthur Moseley, Richele J. Thompson, and John Cavanagh. “Structure and DNA-binding traits of the transition state regulator AbrB.” Structure 22, no. 11 (November 4, 2014): 1650–56. https://doi.org/10.1016/j.str.2014.08.018.
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    • Shao, Hongbing, Celia Baitinger, Erik J. Soderblom, Vickers Burdett, and Paul Modrich. “Hydrolytic function of Exo1 in mammalian mismatch repair.” Nucleic Acids Res 42, no. 11 (June 2014): 7104–12. https://doi.org/10.1093/nar/gku420.
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    • Tucker, Ashley T., Benjamin G. Bobay, Allison V. Banse, Andrew L. Olson, Erik J. Soderblom, M Arthur Moseley, Richele J. Thompson, Kristen M. Varney, Richard Losick, and John Cavanagh. “A DNA mimic: the structure and mechanism of action for the anti-repressor protein AbbA.” J Mol Biol 426, no. 9 (May 1, 2014): 1911–24. https://doi.org/10.1016/j.jmb.2014.02.010.
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    • Xia, Wenle, David Gooden, Leihua Liu, Sumin Zhao, Erik J. Soderblom, Eric J. Toone, Wayne F. Beyer, Harold Walder, and Neil L. Spector. “Photo-activated psoralen binds the ErbB2 catalytic kinase domain, blocking ErbB2 signaling and triggering tumor cell apoptosis.” Plos One 9, no. 2 (2014): e88983. https://doi.org/10.1371/journal.pone.0088983.
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    • Lamoth, Frédéric, Praveen R. Juvvadi, Erik J. Soderblom, M Arthur Moseley, Yohannes G. Asfaw, and William J. Steinbach. “Identification of a key lysine residue in heat shock protein 90 required for azole and echinocandin resistance in Aspergillus fumigatus.” Antimicrob Agents Chemother 58, no. 4 (2014): 1889–96. https://doi.org/10.1128/AAC.02286-13.
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    • Schechter, Matthew A., Michael K. H. Hsieh, Linda W. Njoroge, J Will Thompson, Erik J. Soderblom, Bryan J. Feger, Constantine D. Troupes, et al. “Phosphoproteomic profiling of human myocardial tissues distinguishes ischemic from non-ischemic end stage heart failure.” Plos One 9, no. 8 (2014): e104157. https://doi.org/10.1371/journal.pone.0104157.
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    • Benjamin, Ashlee M., J Will Thompson, Erik J. Soderblom, Scott J. Geromanos, Ricardo Henao, Virginia B. Kraus, M Arthur Moseley, and Joseph E. Lucas. “A flexible statistical model for alignment of label-free proteomics data--incorporating ion mobility and product ion information.” Bmc Bioinformatics 14 (December 16, 2013): 364. https://doi.org/10.1186/1471-2105-14-364.
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    • Richardson, Brenna McJury, Erik J. Soderblom, J Will Thompson, and M Arthur Moseley. “Automated, reproducible, titania-based phosphopeptide enrichment strategy for label-free quantitative phosphoproteomics.” J Biomol Tech 24, no. 1 (April 2013): 8–16. https://doi.org/10.7171/jbt.13-2401-002.
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    • Juvvadi, Praveen Rao, Detti Belina, Erik J. Soderblom, M Arthur Moseley, and William J. Steinbach. “Filamentous fungal-specific septin AspE is phosphorylated in vivo and interacts with actin, tubulin and other septins in the human pathogen Aspergillus fumigatus.” Biochem Biophys Res Commun 431, no. 3 (February 15, 2013): 547–53. https://doi.org/10.1016/j.bbrc.2013.01.020.
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    • Kummarapurugu, Apparao B., Bernard M. Fischer, Shuo Zheng, Ginger L. Milne, Andrew J. Ghio, Erin N. Potts-Kant, W Michael Foster, et al. “NADPH:quinone oxidoreductase 1 regulates host susceptibility to ozone via isoprostane generation.” J Biol Chem 288, no. 7 (February 15, 2013): 4681–91. https://doi.org/10.1074/jbc.M112.438440.
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    • Ralston-Hooper, K. J., M. E. Turner, E. J. Soderblom, D. Villeneuve, G. T. Ankley, M. A. Moseley, R. A. Hoke, and P. L. Ferguson. “Application of a label-free, gel-free quantitative proteomics method for ecotoxicological studies of small fish species.” Environ Sci Technol 47, no. 2 (January 15, 2013): 1091–1100. https://doi.org/10.1021/es303170u.
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    • Soderblom, Erik J., J Will Thompson, Evan A. Schwartz, Edward Chiou, Laura G. Dubois, M Arthur Moseley, and Rahima Zennadi. “Proteomic analysis of ERK1/2-mediated human sickle red blood cell membrane protein phosphorylation.” Clin Proteomics 10, no. 1 (January 3, 2013): 1. https://doi.org/10.1186/1559-0275-10-1.
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    • Juvvadi, Praveen R., Christopher Gehrke, Jarrod R. Fortwendel, Frédéric Lamoth, Erik J. Soderblom, Erik C. Cook, Michael A. Hast, et al. “Phosphorylation of Calcineurin at a novel serine-proline rich region orchestrates hyphal growth and virulence in Aspergillus fumigatus.” Plos Pathog 9, no. 8 (2013): e1003564. https://doi.org/10.1371/journal.ppat.1003564.
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    • Schumacher, Maria A., JungKi Min, Todd M. Link, Ziqiang Guan, Weijun Xu, Young-Ho Ahn, Erik J. Soderblom, et al. “Role of unusual P loop ejection and autophosphorylation in HipA-mediated persistence and multidrug tolerance.” Cell Rep 2, no. 3 (September 27, 2012): 518–25. https://doi.org/10.1016/j.celrep.2012.08.013.
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    • Gu, Jing Jin, Catherine P. Lavau, Elena Pugacheva, Erik J. Soderblom, M Arthur Moseley, and Ann Marie Pendergast. “Abl family kinases modulate T cell-mediated inflammation and chemokine-induced migration through the adaptor HEF1 and the GTPase Rap1.” Sci Signal 5, no. 233 (July 17, 2012): ra51. https://doi.org/10.1126/scisignal.2002632.
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    • Petricka, Jalean J., Monica A. Schauer, Molly Megraw, Natalie W. Breakfield, J Will Thompson, Stoyan Georgiev, Erik J. Soderblom, et al. “The protein expression landscape of the Arabidopsis root.” Proc Natl Acad Sci U S A 109, no. 18 (May 1, 2012): 6811–18. https://doi.org/10.1073/pnas.1202546109.
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    • Zennadi, Rahima, Erin J. Whalen, Erik J. Soderblom, Susan C. Alexander, J Will Thompson, Laura G. Dubois, M Arthur Moseley, and Marilyn J. Telen. “Erythrocyte plasma membrane-bound ERK1/2 activation promotes ICAM-4-mediated sickle red cell adhesion to endothelium.” Blood 119, no. 5 (February 2, 2012): 1217–27. https://doi.org/10.1182/blood-2011-03-344440.
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    • Okada, Hirokazu, Akiyoshi Uezu, Erik J. Soderblom, M Arthur Moseley, Frank B. Gertler, and Scott H. Soderling. “Peptide array X-linking (PAX): a new peptide-protein identification approach.” Plos One 7, no. 5 (2012): e37035. https://doi.org/10.1371/journal.pone.0037035.
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    • Thompson, J. W., and E. J. Soderblom. “Keeping Sample Preparation Simple: Tips on How to Perform Proteomics Measurements with Consistency and Accuracy.” Genetic Engineering and Biotechnology News 31, no. 21 (December 1, 2011): 38–39. https://doi.org/10.1089/gen.31.21.17.
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    • Okada, Hirokazu, Akiyoshi Uezu, Frank M. Mason, Erik J. Soderblom, M Arthur Moseley, and Scott H. Soderling. “SH3 domain-based phototrapping in living cells reveals Rho family GAP signaling complexes.” Sci Signal 4, no. 201 (November 29, 2011): rs13. https://doi.org/10.1126/scisignal.2002189.
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    • Soderblom, Erik J., Melanie Philipp, J Will Thompson, Marc G. Caron, and M Arthur Moseley. “Quantitative label-free phosphoproteomics strategy for multifaceted experimental designs.” Anal Chem 83, no. 10 (May 15, 2011): 3758–64. https://doi.org/10.1021/ac200213b.
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    • Roulhac, Petra L., James M. Ward, J Will Thompson, Erik J. Soderblom, Michael Silva, M Arthur Moseley, and Erich D. Jarvis. “Microproteomics: quantitative proteomic profiling of small numbers of laser-captured cells.” Cold Spring Harb Protoc 2011, no. 2 (February 1, 2011): pdb.prot5573. https://doi.org/10.1101/pdb.prot5573.
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    • Lee, Anthony, Dena L. Toffaletti, Jennifer Tenor, Erik J. Soderblom, J Will Thompson, M Arthur Moseley, Michael Price, and John R. Perfect. “Survival defects of Cryptococcus neoformans mutants exposed to human cerebrospinal fluid result in attenuated virulence in an experimental model of meningitis.” Infect Immun 78, no. 10 (October 2010): 4213–25. https://doi.org/10.1128/IAI.00551-10.
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    • West, Graham M., J Will Thompson, Erik J. Soderblom, Laura G. Dubois, Patrick D. Dearmond, M Arthur Moseley, and Michael C. Fitzgerald. “Mass spectrometry-based thermal shift assay for protein-ligand binding analysis.” Anal Chem 82, no. 13 (July 1, 2010): 5573–81. https://doi.org/10.1021/ac100465a.
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    • Galvão, Rafaelo M., Uma Kota, Erik J. Soderblom, Michael B. Goshe, and Wendy F. Boss. “Characterization of a new family of protein kinases from Arabidopsis containing phosphoinositide 3/4-kinase and ubiquitin-like domains.” Biochem J 409, no. 1 (January 1, 2008): 117–27. https://doi.org/10.1042/BJ20070959.
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    • Whitehurst, Christopher B., Erik J. Soderblom, Michelle L. West, Raquel Hernandez, Michael B. Goshe, and Dennis T. Brown. “Location and role of free cysteinyl residues in the Sindbis virus E1 and E2 glycoproteins.” J Virol 81, no. 12 (June 2007): 6231–40. https://doi.org/10.1128/JVI.02859-06.
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    • Soderblom, Erik J., Benjamin G. Bobay, John Cavanagh, and Michael B. Goshe. “Tandem mass spectrometry acquisition approaches to enhance identification of protein-protein interactions using low-energy collision-induced dissociative chemical crosslinking reagents.” Rapid Commun Mass Spectrom 21, no. 21 (2007): 3395–3408. https://doi.org/10.1002/rcm.3213.
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    • Soderblom, Erik J., and Michael B. Goshe. “Collision-induced dissociative chemical cross-linking reagents and methodology: Applications to protein structural characterization using tandem mass spectrometry analysis.” Anal Chem 78, no. 23 (December 1, 2006): 8059–68. https://doi.org/10.1021/ac0613840.
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    • Liu, Hsiao-Ching S., Erik J. Soderblom, and Michael B. Goshe. “A mass spectrometry-based proteomic approach to study Marek's Disease Virus gene expression.” J Virol Methods 135, no. 1 (July 2006): 66–75. https://doi.org/10.1016/j.jviromet.2006.02.001.
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    • Feeney, Brett, Erik J. Soderblom, Michael B. Goshe, and A Clay Clark. “Novel protein purification system utilizing an N-terminal fusion protein and a caspase-3 cleavable linker.” Protein Expr Purif 47, no. 1 (May 2006): 311–18. https://doi.org/10.1016/j.pep.2005.10.005.
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    • Wang, Xiaofeng, Michael B. Goshe, Erik J. Soderblom, Brett S. Phinney, Jason A. Kuchar, Jia Li, Tadao Asami, Shigeo Yoshida, Steven C. Huber, and Steven D. Clouse. “Identification and functional analysis of in vivo phosphorylation sites of the Arabidopsis BRASSINOSTEROID-INSENSITIVE1 receptor kinase.” Plant Cell 17, no. 6 (June 2005): 1685–1703. https://doi.org/10.1105/tpc.105.031393.
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