Overview
Director, Proteomics and Metabolomics Core Facility
Current Duke Appointments & Affiliations
Associate Research Professor of Cell Biology
·
2023 - Present
Cell Biology,
Basic Science Departments
Recent Scholarly Works
Neuroligin-2 is ubiquitinated by Nedd4l to control developmental astrocyte morphogenesis.
Journal article J Cell Biol · July 6, 2026 Central nervous system astrocytes have an intricate, highly branched morphology. Proper development of perisynaptic astrocyte processes is necessary for tripartite synapse formation and function. However, cellular pathways orchestrating this development ar ... Full text Link to item CiteRegulation of organic anion transporting polypeptide 1B1 transport function by lysine deacetylase 6.
Journal article Mol Pharmacol · July 2026 Hepatic transport protein organic anion transporting polypeptide 1B1 (OATP1B1) is a key determinant of drug-drug interactions. We reported OATP1B1 lysine acetylation recently, however, the lysine deacetylase (KDAC), also known as histone deacetylase (HDAC) ... Full text Link to item CiteInteraction between Rsp5-dependent ubiquitination and trehalose production during Cryptococcus neoformans temperature stress adaptation.
Journal article mSphere · June 30, 2026 Microorganisms, including fungi, adapt to profound changes in their local environment during human infections. After exposure to high temperature and other stress conditions, the opportunistic fungal pathogen Cryptococcus neoformans enacts changes in metab ... Full text Link to item CiteRecent Grants
Regulatory mechanisms governing Th17 cell effector identity and plasticity
ResearchCollaborator · Awarded by National Institute of Allergy and Infectious Diseases · 2025 - 2030Roles for desmsomes in mRNA localization and translational regulation
ResearchCollaborator · Awarded by National Institute of Arthritis and Musculoskeletal and Skin Diseases · 2024 - 2029Calcineurin Control over Aspergillus fumigatus Antifungal Response Mechanisms
ResearchCo Investigator · Awarded by Arkansas Children's Research Institute · 2024 - 2029View All Grants
Education
North Carolina State University ·
2008
Ph.D.