Overview
My work involves the natural history, diagnosis, and therapy of patients with neuroendocrine tumors such as carcinoid tumors and pheochromocytomas. I also am interested in research aspects of diabetes, adrenal cortical disease and pituitary gland disease. My approach has been to make detailed biochemical measurements on patients with the above described diseases in my research lab over my 30 years at Duke. I am now preparing manuscripts containing correlation of data with clinical illness. My data bases contain information on 793 patients with carcinoid tumors and 130 patients with pheochromocytoma.
I have done and continue to do post marketing clinical trials on hypoglycernic medications, octreotide, and alpha interferon. I am recognized as a national expert on neuroendocrine tumors as well as diabetes mellitus.
Key words: Neuroendocrine Tumors, carcinoid tumors, pheochromocytonics, diabetes, hypoglycemic agents, serotonin, catecholamines.
I have done and continue to do post marketing clinical trials on hypoglycernic medications, octreotide, and alpha interferon. I am recognized as a national expert on neuroendocrine tumors as well as diabetes mellitus.
Key words: Neuroendocrine Tumors, carcinoid tumors, pheochromocytonics, diabetes, hypoglycemic agents, serotonin, catecholamines.
Current Appointments & Affiliations
Professor Emeritus of Medicine
·
2000 - Present
Medicine, Endocrinology, Metabolism, and Nutrition,
Medicine
Recent Publications
Detecting pheochromocytoma: defining the most sensitive test.
Journal Article Ann Surg · January 2006 OBJECTIVE: To define the most sensitive biochemical test to establish the diagnosis of pheochromocytoma and also to assess the potential role of iodine 131-labeled metaiodobenzylguanidine scintigraphy (I-MIBG) in the diagnosis of this tumor. SUMMARY BACKGR ... Full text Link to item CiteThe impact of minimally invasive parathyroidectomy on the way endocrinologists treat primary hyperparathyroidism.
Conference Surgery · December 2003 BACKGROUND: Minimally-invasive parathyroidectomy (MIP) appears to be changing preoperative treatment and referral patterns for sporadic, nonfamilial, non-multiple endocrine neoplasia, primary hyperparathyroidism (PHPT). METHODS: The American Association of ... Full text Link to item CiteCarcinoid and chylous ascites: an unusual association.
Journal Article J Gastrointest Surg · 2002 Chylous ascites caused by carcinoid tumors is extremely rare. While carcinoid tumors usually have an indolent course, their association with chylous ascites is a harbinger of a poor outcome. ... Full text Link to item CiteEducation, Training & Certifications
Northwestern University ·
1961
M.D.