Overview
Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins, biology, pathogenesis and drug resistance, and to design new AIDS vaccines.
Current Appointments & Affiliations
Professor Emeritus in Medicine
·
2020 - Present
Medicine, Infectious Diseases,
Medicine
Member of the Duke Human Vaccine Institute
·
2005 - Present
Duke Human Vaccine Institute,
Institutes and Centers
Recent Publications
Biejia-Ruangan enhances the efficacy of entecavir in reversing liver cirrhosis in patients with chronic HBV infection: A seven-year open-label follow-up cohort study.
Journal Article J Ethnopharmacol · January 30, 2026 ETHNOPHARMACOLOGICAL RELEVANCE: Biejia-Ruangan (BRG) has been approved in China as an antifibrotic traditional Chinese medicine for patients with chronic liver diseases; however, data on the reversal of hepatitis B-related cirrhosis by BRG are still limite ... Full text Link to item CiteDNA vaccine targeting betacoronavirus spike protein blocks neuroinvasion and neuroinflammation in swine via dual antiviral-immunomodulatory action
Journal Article Npj Vaccines · December 1, 2025 Porcine hemagglutinating encephalomyelitis virus (PHEV), a neurotropic betacoronavirus, causes fatal neurological disease in piglets, yet no licensed vaccines exist. Here, we developed a DNA vaccine encoding the receptor-binding domain (RBD) of PHEV spike ... Full text CiteNear extinction of the HBV quasispecies driven by the hard selective sweep in chronic hepatitis B.
Journal Article mBio · August 13, 2025 The viral quasispecies play an important role in pathogenesis. However, little is known about the nature of hepatitis B virus (HBV) quasispecies and its impact on the outcomes of chronic hepatitis B. Here, we characterized the bona fide quasispecies viral ... Full text Link to item CiteRecent Grants
Nonhuman Primate Core Virology Laboratory for AIDS Vaccine Research and Development - Base
ResearchInvestigator · Awarded by National Institutes of Health · 2017 - 2024EQAPOL - Years 2017 to 2024 - BASE
ResearchDirector · Awarded by National Institutes of Health · 2017 - 2024Dissection of polyreactivity and neutralization activity of HIV-1 Abs (R01)
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2023View All Grants
Education, Training & Certifications
Harbin Medical University (China) ·
1984
M.D.