Overview
Dr. Feng Gao is Professor of Medicine at Duke University. The Gao laboratory has a long-standing interest in elucidating the origins and evolution of human and simian inmmunodeficiency viruses (HIV and SIV), and in studying HIV/SIV gene function and pathogenic mechanisms from the evolutionary perspective. These studies have led to new strategies to better understand HIV origins, biology, pathogenesis and drug resistance, and to design new AIDS vaccines.
Current Appointments & Affiliations
Professor Emeritus in Medicine
·
2020 - Present
Medicine, Infectious Diseases,
Medicine
Member of the Duke Human Vaccine Institute
·
2005 - Present
Duke Human Vaccine Institute,
Institutes and Centers
Recent Publications
Hyperlipidemia Triggers Trophoblast Cell Dysfunction and Preeclampsia via the AMPK/GATA3/FTL Pathway.
Journal Article Hypertension · July 2025 BACKGROUND: Preeclampsia, a severe pregnancy complication with an incompletely deciphered cause, is strongly associated with hyperlipidemia. Our previous studies demonstrated that FTL (ferritin light chain) expression was diminished in preeclampsia placent ... Full text Link to item CiteNear extinction of the HBV quasispecies driven by the hard selective sweep in chronic hepatitis B.
Journal Article mBio · June 30, 2025 The viral quasispecies play an important role in pathogenesis. However, little is known about the nature of hepatitis B virus (HBV) quasispecies and its impact on the outcomes of chronic hepatitis B. Here, we characterized the bona fide quasispecies viral ... Full text Link to item CiteEchinococcus granulosus-Induced Liver Damage Through Ferroptosis in Rat Model.
Journal Article Cells · February 22, 2025 (1) Background: Cystic echinococcosis (CE) is an Echinococcus granulosus-induced worldwide parasitic zoonosis and is a recognized public health and socio-economic concern. The liver is the major target organ for CE's infective form protoscolex (PSCs), whic ... Full text Link to item CiteRecent Grants
Nonhuman Primate Core Virology Laboratory for AIDS Vaccine Research and Development - Base
ResearchInvestigator · Awarded by National Institutes of Health · 2017 - 2024EQAPOL - Years 2017 to 2024 - BASE
ResearchDirector · Awarded by National Institutes of Health · 2017 - 2024Dissection of polyreactivity and neutralization activity of HIV-1 Abs (R01)
ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2023View All Grants
Education, Training & Certifications
Harbin Medical University (China) ·
1984
M.D.