Liping Feng | Scholars@Duke

Liping Feng
Assistant Professor of Obstetrics and Gynecology

Liping Feng, MD's research has focused on understanding the mechanisms of pregnancy complications associated with infection and maternal chemical exposures. These works are translated then to the clinical care of women through studies dedicated to identify risk factors and novel biomarkers for early prediction and prevention of adverse birth outcomes.

Dr. Feng devotes her entire career to improving pregnancy outcomes through innovative research. Dr. Feng conducts both basic science/laboratory research, as well as participates in clinical studies. Her laboratory has focused on understanding the mechanisms of preterm birth, which is an important cause of perinatal and neonates’ mortality and morbidity. Currently, she has three lines of investigation focused on the roles of inflammation/infection, genetic variation, and environmental exposure in pregnancy complications, such as preterm birth and preeclampsia. This work is translated then to the clinical care of women through studies dedicated to identify risk factors and novel biomarkers for early prediction and prevention of pregnancy complications.

In addition, Dr. Feng has established an international collaboration in Global Women’s Health. She has recently affiliated with the Duke Global Health Institute (DGHI) and participates in a DGHI research. She has an interest in DGHI education, and service or policy initiatives, including mentoring and teaching graduate and professional students on fieldwork and research.

Current Research Interests

Maternal Environmental Exposure of Endocrine Disrupting Chemicals and Pregnancy Outcomes.

Ureaplasma Parvum Infection and Preterm Premature Rupture of Fetal Membranes.

PGRMC1 Functions in Fetal Membranes and Placentas.

How Low-dose Aspirin Prevents Preeclampsia?

Current Appointments & Affiliations

Assistant Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Reproductive Sciences, Obstetrics and Gynecology 2018
Assistant Professor in Pathology, Pathology, Clinical Science Departments 2018
Affiliate, Duke Global Health Institute, Duke Global Health Institute, University Institutes and Centers 2016

Contact Information

303 Research Drive, 246 Sands, Durham, NC 27710
Box 103208, Durham, NC 27710
feng0007@mc.duke.edu (919) 613-1459
Liping Feng

Background
Education, Training, & Certifications
- M.S., Chinese Center for Disease Control and Prevention (China) 2000
- M.D., Harbin Medical University (China) 1997
Duke Appointment History
- Assistant Professor of Obstetrics and Gynecology, Obstetrics and Gynecology, Maternal Fetal Medicine, Obstetrics and Gynecology 2011 - 2018
Leadership & Clinical Positions at Duke
- OB/GYN department Inclusive and Diversity Committee member
Recognition
In the News
- MAY 14, 2018 DukeMed Alumni
  
  MEDx Bridging the Gap Monday, May 14, 2018
- FEB 25, 2014
  
  Stimulating Global Health Research With DGHI Pilot Funds
Awards & Honors
Expertise
Subject Headings
Research
Selected Grants
- Effects of perfluorobutane sulfonate (PFBS) exposure on adverse pregnancy outcomes and fetal development awarded by National Institutes of Health 2017 - 2022
- Cellular and Molecular Systems Biology of Preterm Birth awarded by University of Chicago 2015 - 2020
- Mechanisms of Progesterone mediated effect on cytokine induced Metalloproteinase activity in human trophoblast cells awarded by Society for Obstetric Anesthesia and Perinatology 2012 - 2014
- Progesterone Receptor Membrane Component 1 (PGRMC1) as a Predictor of Preterm Birth awarded by The Biomarker Factory 2013 - 2014
- DMID 05-0048 Tdap Vaccine in Pregnant Women awarded by University of Maryland 2010 - 2012
- DMID 09-0005 Safety and Immunogenicity awarded by University of Maryland 2010 - 2012
- 09-0056 A Phase II Study in Pregnant Women to Assess H1N1 Vaccine awarded by University of Maryland 2009 - 2010
- A randomized double-blind trial on the safety and immunogenicity of inactivated trivalent influenza vaccine in pregnant awarded by University of Maryland 2009 - 2010
Fellowships, Supported Research, & Other Grants
- The development of a novel platform closely mimicking the human placental barrier awarded by MEDx Biomedical Research Fund 2017 - 2018
- Maternal exposure to e-waste in Guiyu, China and birth outcomes awarded by Duke Global Health Institute GEM Pilot Grant 2017 - 2018
- Understanding the pathogenicity of U. parvum among women and infants awarded by Duke Perinatal Research Fund 2015
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Feng, L, Allen, TK, Marinello, WP, and Murtha, AP. "Roles of Progesterone Receptor Membrane Component 1 in Oxidative Stress-Induced Aging in Chorion Cells." Reproductive Sciences (Thousand Oaks, Calif.) 26, no. 3 (March 2019): 394-403. Full Text
  - Ye, Y, Tang, Y, Xiong, Y, Feng, L, and Li, X. "Bisphenol A exposure alters placentation and causes preeclampsia-like features in pregnant mice involved in reprogramming of DNA methylation of WNT2." Faseb Journal : Official Publication of the Federation of American Societies for Experimental Biology 33, no. 2 (February 2019): 2732-2742. Full Text
  - Huang, R, Chen, Q, Zhang, L, Luo, K, Chen, L, Zhao, S, Feng, L, and Zhang, J. "Prenatal exposure to perfluoroalkyl and polyfluoroalkyl substances and the risk of hypertensive disorders of pregnancy." Environmental Health : a Global Access Science Source 18, no. 1 (January 9, 2019): 5-null. Full Text
  - Feng, L. "Reply." American Journal of Obstetrics and Gynecology 220, no. 1 (January 2019): 126-null. (Letter) Full Text
  - Allen, TK, Nazzal, MN, Feng, L, Buhimschi, IA, and Murtha, AP. "Progestins Inhibit Tumor Necrosis Factor α-Induced Matrix Metalloproteinase 9 Activity via the Glucocorticoid Receptor in Primary Amnion Epithelial Cells." Reproductive Sciences (Thousand Oaks, Calif.) (November 19, 2018): 1933719118811646-null. Full Text
  - Ye, J, Chen, Y, Zhu, J, Chen, C, Zhu, X, Feng, L, Ye, W, and Zhang, J. "Aspirin use during pregnancy and hypoxia-related placental pathology." Pregnancy Hypertension 14 (October 2018): 177-188. Full Text
  - Feng, L, Allen, TK, Marinello, WP, and Murtha, AP. "Infection-induced thrombin production: a potential novel mechanism for preterm premature rupture of membranes (PPROM)." American Journal of Obstetrics and Gynecology 219, no. 1 (July 2018): 101.e1-101.e12. Full Text Open Access Copy
  - Ye, Y, Zhou, Q, Feng, L, Wu, J, Xiong, Y, and Li, X. "Maternal serum bisphenol A levels and risk of pre-eclampsia: a nested case-control study." European Journal of Public Health 27, no. 6 (December 2017): 1102-1107. Full Text
  - Smrtka, MP, Feng, L, Murtha, AP, and Grotegut, CA. "Thrombin-Induced Inflammation in Human Decidual Cells Is Not Affected By Heparin." Reproductive Sciences (Thousand Oaks, Calif.) 24, no. 8 (August 2017): 1154-1163. Full Text
  - Wang, X, Ouyang, F, Feng, L, Wang, X, Liu, Z, and Zhang, J. "Maternal Urinary Triclosan Concentration in Relation to Maternal and Neonatal Thyroid Hormone Levels: A Prospective Study." Environmental Health Perspectives 125, no. 6 (June 27, 2017): 067017-null. Full Text
  - Ju, R, Siddiqui, N, Garrett, J, Feng, L, and Heit, M. "A validated translation of a survey for measuring incontinence knowledge in Chinese-speaking American immigrants." International Urogynecology Journal 28, no. 6 (June 2017): 851-856. Full Text
  - Feng, L, Jayes, FL, Johnson, LNC, Schomberg, DW, and Leppert, PC. "Biochemical Pathways and Myometrial Cell Differentiation Leading to Nodule Formation Containing Collagen and Fibronectin." Current protein & peptide science 18, no. 2 (January 2017): 155-166. Full Text
  - Meng, Y, Murtha, AP, and Feng, L. "Progesterone, Inflammatory Cytokine (TNF-α), and Oxidative Stress (H2O2) Regulate Progesterone Receptor Membrane Component 1 Expression in Fetal Membrane Cells." Reproductive sciences (Thousand Oaks, Calif.) 23, no. 9 (September 2016): 1168-1178. Full Text
  - Potts, LC, Feng, L, Seed, PC, Jayes, FL, Kuchibhatla, M, Antczak, B, Nazzal, MK, and Murtha, AP. "Inflammatory Response of Human Gestational Membranes to Ureaplasma parvum Using a Novel Dual-Chamber Tissue Explant System." Biology of reproduction 94, no. 5 (May 2016): 119-. Full Text
  - Feng, L, Ouyang, F, Liu, L, Wang, X, Wang, X, Li, Y-J, Murtha, A, Shen, H, Zhang, J, and Zhang, JJ. "Levels of Urinary Metabolites of Organophosphate Flame Retardants, TDCIPP, and TPHP, in Pregnant Women in Shanghai." Journal of Environmental and Public Health 2016 (January 2016): 9416054-null. Full Text Open Access Copy
  - Feng, L, Ransom, CE, Nazzal, MK, Allen, TK, Li, Y-J, Truong, T, Potts, LC, Seed, PC, and Murtha, AP. "The Role of Progesterone and a Novel Progesterone Receptor, Progesterone Receptor Membrane Component 1, in the Inflammatory Response of Fetal Membranes to Ureaplasma parvum Infection." Plos One 11, no. 12 (January 2016): e0168102-null. Full Text
  - Allen, TK, Feng, L, Nazzal, M, Grotegut, CA, Buhimschi, IA, and Murtha, AP. "The Effect of Progestins on Tumor Necrosis Factor α-Induced Matrix Metalloproteinase-9 Activity and Gene Expression in Human Primary Amnion and Chorion Cells In Vitro." Anesthesia and Analgesia 120, no. 5 (May 2015): 1085-1094. Full Text
  - Feng, L, Allen, TK, Nazzal, MK, and Murtha, AP. "P4 and Progesterone Membrane Component 1 (PGRMC1) Inhibit Ureaplasma Parvum Induced Inflammation in Amnion and Chorion Cells." REPRODUCTIVE SCIENCES 22 (March 1, 2015): 236A-237A. Link to Item
  - Feng, L, Allen, TK, and Murtha, AP. "Role of P4 and Progesterone Receptor Membrane Component 1 (PGRMC1) in Sirtuin1 and Sirtuin 3 Regulation in Chorion Cells Under Oxidative Stress." REPRODUCTIVE SCIENCES 22 (March 1, 2015): 326A-326A. Link to Item
  - Huang, L, Liu, J, Feng, L, Chen, Y, Zhang, J, and Wang, W. "Maternal prepregnancy obesity is associated with higher risk of placental pathological lesions." Placenta 35, no. 8 (August 2014): 563-569. Full Text
  - Feng, L, Antczak, BC, Lan, L, Grotegut, CA, Thompson, JL, Allen, TK, and Murtha, AP. "Progesterone receptor membrane component 1 (PGRMC1) expression in fetal membranes among women with preterm premature rupture of the membranes (PPROM)." Placenta 35, no. 5 (May 2014): 331-333. Full Text
  - Allen, TK, Feng, L, Grotegut, CA, and Murtha, AP. "Progesterone receptor membrane component 1 as the mediator of the inhibitory effect of progestins on cytokine-induced matrix metalloproteinase 9 activity in vitro." Reprod Sci 21, no. 2 (February 2014): 260-268. Full Text Link to Item
  - Murtha, AP, Fortner, KB, Grotegut, CA, Ransom, CE, Bentley, RC, Feng, L, Lan, L, Heine, RP, and Seed, PC. "Bacteria Localization and Chorion Thinning among Preterm Premature Rupture of Membranes." Plos One (January 8, 2014). (Academic Article) Full Text Open Access Copy
  - Kraus, DM, Feng, L, Heine, RP, Brown, HL, Caron, KM, Murtha, AP, and Grotegut, CA. "Cigarette smoke-induced placental adrenomedullin expression and trophoblast cell invasion." Reprod Sci 21, no. 1 (January 2014): 63-71. Full Text Link to Item
  - Grotegut, CA, Gunatilake, RP, Feng, L, Heine, RP, and Murtha, AP. "The influence of maternal body mass index on myometrial oxytocin receptor expression in pregnancy." Reproductive Sciences (Thousand Oaks, Calif.) 20, no. 12 (December 2013): 1471-1477. Full Text
  - Canzoneri, BJ, Feng, L, Grotegut, CA, Bentley, RC, Heine, RP, and Murtha, AP. "The chorion layer of fetal membranes is prematurely destroyed in women with preterm premature rupture of the membranes." Reprod Sci 20, no. 10 (October 2013): 1246-1254. Full Text Link to Item
  - Beiswenger, TR, Feng, L, Brown, HL, Heine, RP, Murtha, AP, and Grotegut, CA. "The effect of cigarette smoke extract on trophoblast cell viability and migration: the role of adrenomedullin." Reprod Sci 19, no. 5 (May 2012): 526-533. Full Text Link to Item
  - Allen, TK, Feng, L, Grotegut, CA, and Murtha, AP. "Progestins Diminish Cytokine Induced MMP9 Activity in a Human Cytotrophoblast Cell Line Not Expressing the Nuclear Progesterone Receptor." REPRODUCTIVE SCIENCES 19, no. S3 (March 1, 2012): 294A-294A. Link to Item
  - Feng, L, Antczak, B, Thompson, J, Grotegut, CA, and Murtha, AP. "PGRMC1 Expression in Fetal Membrane Layers among Women with Preterm Premature Rupture of the Membranes (PPROM)." REPRODUCTIVE SCIENCES 19, no. S3 (March 1, 2012): 295A-295A. Link to Item
  - Gunatilake, R, Yeh, J, Feng, L, Jayes, F, Leppert, P, Heine, RP, Murtha, A, and Grotegut, C. "An Elevated Leptin Obese Mouse Model Demonstrates Uterine Fibrosis and Decreased Uterine Contractility in Response to Oxytocin." REPRODUCTIVE SCIENCES 19, no. S3 (March 1, 2012): 195A-196A. Link to Item
  - Ransom, CE, Seed, PC, Fortner, KB, Feng, L, Lan, L, Yu, M, and Murtha, AP. "Differential Cytokine and Tissue Remodeling Responses in Chorion and Decidua Exposed to Ureaplasma parvum." REPRODUCTIVE SCIENCES 19, no. S3 (March 1, 2012): 362A-363A. Link to Item
  - Roeder, H, Jayes, F, Feng, L, and Leppert, PC. "CDB-4124 does not cause apoptosis in cultured fibroid cells." Reprod Sci 18, no. 9 (September 2011): 850-857. Full Text Link to Item
  - Feng, L, Grotegut, C, Schomberg, D, and Murtha, AP. "Progesterone Receptor Membrane Component 1 Mediated Signaling Inhibits Increase in Intracellular Ca2+ in Human Cytotrophoblast Cells." REPRODUCTIVE SCIENCES 18, no. 3 (March 2011): 312A-313A. Link to Item
  - Fortner, KB, Ransom, CE, Canzoneri, BJ, Bentley, RC, Feng, L, Seed, PC, and Murtha, AP. "Bacteria Localization in Fetal Membranes among Subjects with Preterm Premature Rupture of Membranes." REPRODUCTIVE SCIENCES 18, no. 3 (March 1, 2011): 238A-238A. Link to Item
  - Grotegut, CA, Feng, L, Mao, L, Heine, RP, Murtha, AP, and Rockman, HA. "β-Arrestin mediates oxytocin receptor signaling, which regulates uterine contractility and cellular migration." Am J Physiol Endocrinol Metab 300, no. 3 (March 2011): E468-E477. Full Text Link to Item
  - Wu, J, Feng, L, and Hsieh, T-S. "Drosophila topo IIIalpha is required for the maintenance of mitochondrial genome and male germ-line stem cells." Proc Natl Acad Sci U S A 107, no. 14 (April 6, 2010): 6228-6233. Full Text Link to Item
  - Jung, S-H, Sohn, I, George, SL, Feng, L, and Leppert, PC. "Sample size calculation for microarray experiments with blocked one-way design. (Published online)" BMC Bioinformatics 10 (May 28, 2009): 164-. Full Text Link to Item
  - Jayes, FL, Proia, AD, Dash, RC, Feng, L, and Leppert, PC. "The Duke Uterine Fibroid Tissue Repository - A Stepping Stone for Translational Research." REPRODUCTIVE SCIENCES 16, no. 3 (March 1, 2009): 210A-211A. Link to Item
  - Murtha, AP, Feng, L, Grotegut, C, and Schomberg, D. "Expression of COX2 and GPX2 Are Altered by Calcimycin but Not Progesterone in Fetal Chorion Cells." REPRODUCTIVE SCIENCES 16, no. 3 (March 2009): 295A-296A. Link to Item
  - Wu, J, Capp, C, Feng, L, and Hsieh, T-S. "Drosophila homologue of the Rothmund-Thomson syndrome gene: essential function in DNA replication during development." Dev Biol 323, no. 1 (November 1, 2008): 130-142. Full Text Link to Item
  - Behera, MA, Feng, L, Yonish, B, Catherino, W, Jung, SH, and Leppert, P. "Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline (Reproductive Sciences (2007) 14, 8, (63S-76S) DOI: 10.1177/1933719107309591)." Reproductive Sciences 15, no. 1 (January 1, 2008): 97-null. Full Text
  - Behera, MA, Feng, L, Yonish, B, Catherino, W, Jung, S-H, and Leppert, P. "Thrombospondin-1 and thrombospondin-2 mRNA and TSP-1 and TSP-2 protein expression in uterine fibroids and correlation to the genes COL1A1 and COL3A1 and to the collagen cross-link hydroxyproline." Reprod Sci 14, no. 8 Suppl (December 2007): 63-76. Full Text Link to Item
  - Murtha, AP, Feng, L, Yonish, B, Leppert, PC, and Schomberg, DW. "Progesterone protects fetal chorion and maternal decidua cells from calcium-induced death." Am J Obstet Gynecol 196, no. 3 (March 2007): 257.e1-257.e5. Full Text Link to Item
  - Mills, AA, Yonish, B, Feng, L, Schomberg, DW, Heine, RP, and Murtha, AP. "Characterization of progesterone receptor isoform expression in fetal membranes." Am J Obstet Gynecol 195, no. 4 (October 2006): 998-1003. Full Text Link to Item
  - Yan, H, Feng, L, LaBean, TH, and Reif, JH. "Parallel molecular computations of pairwise exclusive-or (XOR) using DNA "string tile" self-assembly." Journal of the American Chemical Society 125, no. 47 (November 2003): 14246-14247. Full Text
  - Feng, L, Park, SH, Reif, JH, and Yan, H. "A two-state DNA lattice switched by DNA nanoactuator." Angew Chem Int Ed Engl 42, no. 36 (September 22, 2003): 4342-4346. Full Text Link to Item
  - Yan, H, LaBean, TH, Feng, L, and Reif, JH. "Directed nucleation assembly of DNA tile complexes for barcode-patterned lattices." Proceedings of the National Academy of Sciences of the United States of America 100, no. 14 (July 2003): 8103-8108. Full Text
- Conference Papers
  - Allen, TK, Marinello, W, Feng, L, Murtha, A, and Buhimschi, I. "Progestins Inhibit IL1b-Induced MMP1 and IL8 mRNA Expression in Amnion Mesenchymal Cells through the Glucocorticoid Receptor." 65th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI). San Diego, CA. March 6, 2018 - March 10, 2018.: SAGE PUBLICATIONS INC, March 1, 2018. Link to Item
  - Allen, TK, Feng, L, Marinello, W, Buhimischi, IA, and Murtha, AP. "Progestins Inhibit IL1 beta Induced MMP9 Activity and GM-CSF Production from Primary Chorion Cells." 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI). Orlando, FL. March 15, 2017 - March 18, 2017. SAGE PUBLICATIONS INC, March 1, 2017. Link to Item
  - Feng, L, Antonia, A, Murtha, A, and Ko, D. "Racial Disparity in Ureaplasma Parvum Induced Inflammatory Responses." 64th Annual Scientific Meeting of the Society-for-Reproductive-Investigation (SRI). Orlando, FL. March 15, 2017 - March 18, 2017.: SAGE PUBLICATIONS INC, March 1, 2017. Link to Item
  - Allen, T, Nazzal, M, Feng, L, Buhimschi, I, and Murtha, A. "The Role of PGRMC1 in Cytokine Induced MMP1, COX-2 and PGE(2) Expression in Amnion Mesenchymal Cells." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016. Link to Item
  - Feng, L, Desravine, N, Nazzal, M, Pryor, K, and Murtha, A. "Characterization of Progesterone Receptor Membrane Component 1 in Peripheral Blood Mononuclear Cells and Plasma During Pregnancy." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016. Link to Item
  - Kim, E, Allen, TK, Feng, L, Nazzal, MK, and Murtha, AP. "The Effect of Cytokines on Neutrophil Gelatinase-Associated Lipocalin (NGAL) mRNA Expression in a Cytotrophoblast Cell Line." 63rd Annual Scientific Meeting of the Society-for-Reproductive-Investigation. Montreal, CANADA. March 16, 2016 - March 19, 2016. SAGE PUBLICATIONS INC, March 1, 2016. Link to Item
  - Potts, LC, Feng, L, Jayes, FL, and Murtha, AP. "341: Novel ex vivo system to evaluate inflammation of gestational membranes in response to U. parvum." January 2016. Full Text
  - Pryor, K, Wheeler, S, Whitaker, R, Feng, L, and Murtha, A. "691: Evidence of PGRMC1 expression in cervical and vaginal epithelial cells during pregnancy." January 2016. Full Text
  - Thompson, J, Feng, L, Antczak, B, Seed, P, and Murtha, A. "13: Inhibition of toll-like receptors and inflammatory response in primary chorion cells." December 2015. Full Text
  - Thompson, J, Fortner, K, Antczak, B, Feng, L, Thomas, S, Grotegut, C, Seed, P, and Murtha, A. "791: Immunohistochemical distribution of toll-like receptors in human fetal membranes." January 2014. Full Text
  - Smrtka, MP, Grotegut, CA, Feng, L, and Murtha, AP. "Thrombin-Induced Tissue Factor Expression in Human Decidual Cells Is Not Affected by Enoxaparin." 60th Annual Scientific Meeting of the Society-for-Gynecologic-Investigation (SGI). Orlando, FL. March 20, 2013 - March 23, 2013. SAGE PUBLICATIONS INC, March 1, 2013. Link to Item
  - Thompson, JL, Antczak, BC, Feng, L, Grotegut, CA, Seed, PC, and Murtha, AP. "Distribution of Toll-Like Receptor 4 in Preterm Fetal Membranes." 60th Annual Scientific Meeting of the Society-for-Gynecologic-Investigation (SGI). Orlando, FL. March 20, 2013 - March 23, 2013. SAGE PUBLICATIONS INC, March 1, 2013. Link to Item
  - Kraus, D, Feng, L, Heine, RP, Brown, H, Murtha, A, and Grotegut, C. "43: Smoking and preeclamspia protection: cigarette smoke increases placental adrenomedullin expression and improves trophoblast invasion via the adrenomedullin pathway." January 2013. Full Text
  - Gilner, JB, Murtha, A, and Feng, L. "Progesterone Protects Chorion Cells from Apoptosis Induced by Reactive Oxygen Species." : SAGE PUBLICATIONS INC, March 1, 2012. Link to Item
  - Choi, SJ, Feng, L, Gilner, J, and Murtha, A. "523: The effect of progesterone on TNF-α induced MMP 9 activity in human fetal membranes." January 2012. Full Text
  - Gunatilake, R, Feng, L, Swamy, G, Heine, RP, Murtha, A, and Grotegut, C. "318: Oxytocin receptor expression in uterine myometrium is not influenced by body mass index." : Elsevier BV, January 2011. Full Text
  - Murtha, A, Grotegut, C, Heine, RP, and Feng, L. "46: Progesterone receptor membrane component 1 (PGRMC1) inhibits Ca2+ mediated cell death in human cytotrophoblast cells." : Elsevier BV, January 2011. Full Text
  - Feng, L, Jayes, FL, Jung, S-H, and Leppert, PC. "VITAMIN D RECEPTOR (VDR) IS OVER-EXPRESSED IN THE CENTER OF UTERINE FIBROIDS." September 2010. Full Text Link to Item
  - Feng, L, and Murtha, AP. "R5020 Inhibits Calcium Ionophore-Induced Apoptosis in Trophoblast Cells by Regulating Intracellular Calcium." March 2010. Link to Item
  - Roeder, HA, Jayes, FL, Feng, L, and Leppert, PC. "Proellex Does Not Cause Apoptosis in Cultured Fibroid Cells." 57th Annual Meeting of the Society-for-Gynecologic-Investigation. Orlando, FL. March 24, 2010 - March 27, 2010. SAGE PUBLICATIONS INC, March 1, 2010. Link to Item
  - Johnson, LNC, Jayes, FL, Feng, L, and Leppert, PC. "Factors Involved in Early Uterine Fibroid Development: The Initiation of Early Wound Healing Responses in Myometrial Cells." 43rd Annual Meeting of the Society-for-the-Study-of-Reproduction. Milwaukee, WI. July 31, 2010 - August 3, 2010. SOC STUDY REPRODUCTION, January 1, 2010. Link to Item
  - Beiswenger, T, Grotegut, C, Feng, L, Heine, P, and Murtha, A. "The effects of cigarette smoke on cell viability and angiogenic factors in a cytotrophoblast cell line." December 2009. Full Text Link to Item
  - Gavrilova-Jordan, LP, Schomberg, D, Feng, L, Jayes, FL, Murtha, A, and Price, TM. "Expression of a Truncated Progesterone Receptor Isoform (PR-M) in Pregnant and Laboring Myometrium." 56th Annual Meeting of the Society-for-Gynecologic-Investigation. Glasgow, SCOTLAND. March 17, 2009 - March 21, 2009. SAGE PUBLICATIONS INC, March 1, 2009. Link to Item
  - Gavrilova-Jordan, LP, Zhang, L, Schomberg, D, Jayes, FL, Feng, L, and Price, TM. "Expression of a Truncated Progesterone Receptor (PR-M) Correlates with Mitochondrial Content in Human Tissues." 56th Annual Meeting of the Society-for-Gynecologic-Investigation. Glasgow, SCOTLAND. March 17, 2009 - March 21, 2009. SAGE PUBLICATIONS INC, March 1, 2009. Link to Item
  - Murphy, SK, Jayes, FL, Feng, L, Huang, Z, and Leppert, PC. "Methylation of THBS1, the Gene Encoding Thrombospondin-1 in Uterine Fibroids and Myometrium." March 2009. Link to Item
  - Murphy, SK, Jayes, FL, Feng, L, Huang, Z, and Leppert, PC. "Altered IGF2/H19 Imprint Center Methylation in Uterine Fibroids but Not in Adjacent Myometrium." 56th Annual Meeting of the Society-for-Gynecologic-Investigation. Glasgow, SCOTLAND. March 17, 2009 - March 21, 2009. SAGE PUBLICATIONS INC, March 1, 2009. Link to Item
  - Feng, L, Behera, M, Jayes, F, and Leppert, P. "Uterine fibroids: Development of a cell model of early fibroid growth." 55th Annual Meeting of the Society-for-Gynecologic-Investigation. San Diego, CA. March 26, 2008 - March 29, 2008. SAGE PUBLICATIONS INC, February 1, 2008. Link to Item
  - Grotegut, CA, Canzoneri, BJ, Feng, L, Heine, P, and Murtha, AP. "Cigarette smoke extract causes cell death in cultured human chorion and decidua cells." 55th Annual Meeting of the Society-for-Gynecologic-Investigation. San Diego, CA. March 26, 2008 - March 29, 2008. SAGE PUBLICATIONS INC, February 1, 2008. Link to Item
  - Murtha, A, Feng, L, Yonish, B, Bone, J, Heine, P, and Schomberg, DW. "52: Progesterone causes altered proinflammatory, cytoprotective gene expression in fetal chorion cells." : Elsevier BV, December 2007. Full Text
  - Murtha, A, Feng, L, Yonish, B, and Schomberg, D. "Progesterone protects chorion and decidua cells from calcium induced cell death in primary cell culture." December 2006. Full Text
  - Mills, A, Yonish, B, Feng, L, and Murtha (F), A. "Characterization of progesterone receptor isoform expression in fetal membranes." December 2005. Full Text
  - Yan, H, Yin, P, Park, SH, Li, HY, Feng, LP, Guan, XJ, Liu, DG, Reif, JH, and LaBean, TH. "Self-assembled DNA structures for nanoconstruction." International Symposium on DNA-Based Molecular Electronics. Jena, GERMANY. May 13, 2004 - May 15, 2004. AMER INST PHYSICS, January 1, 2004. Link to Item
  - LaBean, TH, Yan, H, Park, SH, Feng, LP, Yin, P, Li, HY, Ahn, SJ, Liu, D, Guan, XJ, and Reif, JH. "Overview of new structures for DNA-Based nanofabrication and computation." 7th Joint Conference on Information Sciences (JCIS). RES TRIANGLE PK, NC. September 26, 2003 - September 30, 2003. ASSOC INTELLIGENT MACHINERY, January 1, 2003. Link to Item
Teaching & Mentoring
Recent Courses
- GLHLTH 395: Connections in Global Health: Interdisciplinary Team Projects 2019
- GLHLTH 795: Connections in Global Health: Interdisciplinary Team Projects 2019
Advising & Mentoring
- Mentor to fellows and residents in OB/GYN department including: Drs. Daniel Kraus, Kimberly Fortner, Ravindu Gunatilake, Carla Ransom, Jennifer Thomson, Michael Smrtka, James Edwards, Amber Wood, Sarahn Wheeler.
  
  Visiting Scholars: Drs. Seong Jin, Terrence Allen, Liwen Zhang, Yan Meng.
  
  Students: Patrick, Jane, Yechen Hu, Henry Chen, Hope Jackson.
  
  Current Trainees: Christina Figan, Junjiao Song, Megan Varvoutis, Annalies Denoble, Hope Jackson.
Scholarly, Clinical, & Service Activities
Presentations & Appearances
Outreach & Engaged Scholarship
- Mentors to NCSM High School Student. 2017 2017
Service to Duke
- OB/GYN Inclusive and Diversity Committee. 2017 2017
- Duke Medical School Admission. 2016 - 2018 2016 - 2018
Academic & Administrative Activities
- OB/GYN Department Inclusive and Diversity Committee Member

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Education, Training, & Certifications

Duke Appointment History

Leadership & Clinical Positions at Duke

In the News

Awards & Honors

Subject Headings

Selected Grants

Fellowships, Supported Research, & Other Grants

Selected Publications

Academic Articles

Conference Papers

Recent Courses

Advising & Mentoring

Presentations & Appearances

Outreach & Engaged Scholarship

Service to Duke

Academic & Administrative Activities