Ferdinand Kappes

Associate Professor of the Practice of Interdisciplinary Studies at DKU Unit at Duke University · 2025 - Present Interdisciplinary Studies at DKU Unit, DKU Faculty

Recent Scholarly Works

Selective under-representation of transcripts encoding membrane-integrated architectures following neural tissue vitrification.

Journal article Biochem Biophys Rep · December 2026 Cryopreservation is essential for long-term storage of biological tissues. Yet, surprisingly, the impact of cryopreservation on tissue transcriptomes remains poorly defined. This study used bulk RNA sequencing to examine how preservation method (snap freez ... Full text Link to item Cite

Exposure to PFOA and GenX elicits cell typespecific impacts on p53 and TGF-β signaling pathways.

Journal article Mol Biol Rep · February 27, 2026 Per- and polyfluoroalkyl substances (PFAS) are a class of synthetic chemicals extensively used as plastic additives. Their environmental persistence and potential for bioaccumulation have raised significant toxicological concerns. This study evaluates the ... Full text Link to item Cite

Phosphorylation of serines 287/288 in DEK regulates cell-type-specific chromatin occupancy and compaction

Preprint · 2026 The conserved multifunctional chromatin modulator and oncogene DEK exhibits context-dependent genomic binding and function, but how these activities are regulated in cancer remains poorly understood. Using multi-omics and biochemical approaches, we find th ... Full text Cite

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Education

University of Konstanz (Germany) · 1999 Ph.D.