Research Interests
My current research interests are four fold. First, I am developing statistical methods to incorporate causal inference techniques into the design and analysis of clinical trials or generally randomized experiments, e.g. constructing external controls of clinical trials from real world data, best practice of covariate adjustment in randomized trials. Second, I am exploring the interface between causal inference and machine learning, e.g. how to borrow insights from causal inference into fundamental problems in machine learning such as measuring feature importance. Third, I am investigating how to analyze natural experiments with complex data. Fourth, I am developing computational and software tools to bridge the theory and practice of causal inference (aka comparative effectiveness research).
Selected Grants
Deprescribing Decision-Making using Machine Learning Individualized Treatment Rules to Improve CNS Polypharmacy
ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2029Principal stratification methods and software for intercurrent events in clinical trials
ResearchPrincipal Investigator · Awarded by University of North Carolina - Chapel Hill · 2023 - 2028Innovative Biostatistical Methods for Analysis and Assessment of Clinical Trials Augmented by Real World Data
ResearchCo Investigator · Awarded by Burroughs Wellcome Fund · 2021 - 2026The biodemography of early adversity: social behavioral processes in a wild animal model.
ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2018 - 2024Religion, Spirituality and CVD Risks: A Focus on African Americans
ResearchStatistician · Awarded by National Institutes of Health · 2017 - 2024New causal inference methods for cluster randomized trials with post-randomization selection
ResearchPrincipal Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2020 - 2024Addressing Bias from Missing Data in EHR Based Studies of CVD
ResearchCollaborator · Awarded by National Institutes of Health · 2018 - 2023A life course perspective on the effects of cumulative early adversity on health
ResearchCo-Principal Investigator · Awarded by University of Notre Dame · 2017 - 2023Prospective Multicenter Observational Cohort Study of Comparative Effectiveness of Disease-Modifying Treatments for Myasthenia Gravis (MG)
Clinical TrialStatistical Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2017 - 2022Methods for the Design and Conduct of Subgroup Analysis in Observational Studies
ResearchCo Investigator · Awarded by Patient-Centered Outcomes Research Institute · 2019 - 2022New weighting methods for causal inference
ResearchPrincipal Investigator · Awarded by National Science Foundation · 2014 - 2017NCRN-MN:Triangle Census Research Network
ResearchCo Investigator · Awarded by National Science Foundation · 2011 - 2016Collaborative Research: Statistical Modeling and Inference for High-dimensional Multi-Subject Neuroimaging Data
ResearchPrincipal Investigator · Awarded by National Science Foundation · 2012 - 2015Bayesian multivariate analysis for causal inference with intermediate variable
ResearchPrincipal Investigator · Awarded by National Science Foundation · 2012 - 2015Fellowships, Gifts, and Supported Research
Seed Grant: Duke’s Society of Women in Science ·
2023
- 2024
PI ·
Awarded by: Duke Office for Faculty Advancement
External Relationships
- Columbia University
- GSK
- North Carolina Department of Justice
- VHB
This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.