Overview
Determinants of Outcome in Patients with Staphylococcus aureus Bacteremia
Antibacterial Resistance
Pathogenesis of Bacterial Infections
Tropical medicine/International Health
Antibacterial Resistance
Pathogenesis of Bacterial Infections
Tropical medicine/International Health
Current Appointments & Affiliations
Florence McAlister Distinguished Professor of Medicine
·
2019 - Present
Medicine, Infectious Diseases,
Medicine
Professor of Medicine
·
2012 - Present
Medicine, Infectious Diseases,
Medicine
Professor in Molecular Genetics and Microbiology
·
2012 - Present
Molecular Genetics and Microbiology,
Basic Science Departments
Member in the Duke Clinical Research Institute
·
2001 - Present
Duke Clinical Research Institute,
Institutes and Centers
Recent Publications
Escherichia coli Type III Secretion System 2 (ETT2) is Associated with Patient Mortality in Bloodstream Infections.
Journal Article J Infect Dis · May 22, 2025 BACKGROUND: Escherichia coli has an extensive accessory genome, though its role in impacting patient mortality is unknown. METHODS: We performed whole genome sequencing with E. coli bloodstream infection isolates from inpatients at Duke University. Pan-gen ... Full text Link to item CiteThe lack of a biorepository during vaccine trials: A lost opportunity to understand staphylococcal immunity.
Journal Article Vaccine · April 19, 2025 Development of a vaccine against Staphylococcus aureus has proven to be difficult, in no small measure due to our lack of understanding of the human immune response to this pathogen. Because the human immune response is distinct from other species often us ... Full text Link to item CiteManagement of Staphylococcus aureus Bacteremia: A Review.
Journal Article JAMA · April 7, 2025 IMPORTANCE: Staphylococcus aureus, a gram-positive bacterium, is the leading cause of death from bacteremia worldwide, with a case fatality rate of 15% to 30% and an estimated 300 000 deaths per year. OBSERVATIONS: Staphylococcus aureus bacteremia causes m ... Full text Link to item CiteRecent Grants
Genomic determinants of antibiotic treatment failure in S. aureus bacteremia
ResearchMentor · Awarded by National Institutes of Health · 2024 - 2029Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program
Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2022 - 2027Staphylococcus aureus Cardiac Device Infections - From the Vascular Viewpoint (K23)
ResearchMentor · Awarded by National Heart, Lung, and Blood Institute · 2022 - 2027View All Grants
Education, Training & Certifications
Duke University ·
1999
M.H.S.
University of North Carolina, Chapel Hill ·
1993
M.D.