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Allan Howard Friedman

Guy L. Odom Distinguished Professor of Neurosurgery, in the School of Medicine
Box 3807 Med Ctr, Durham, NC 27710
4520 Hosp South - Blue Zone, 7688A Hafs Bldg, Durham, NC 27710


At the present time, I am participating in collaborative research in the areas of primary malignant brain tumors, epilepsy and subarachnoid hemorrhage.

Primary malignant brain tumors are increasing in frequency. Patients harboring glioblastoma, the most malignant primary brain tumor, have a life expectancy of less than one year. In collaboration with the Division of Neurology and the Department of Pathology, clinical and laboratory trials have been initiated to identify better treatment for this condition. At present, trials of monoclonal antibodies and novel chemotherapeutic agents are being carried out.

Although physicians have been interested in seizures since the time of Hippocrates, the origin of seizures remains obscure. At Duke University we have treated approximately thirty seizure patients a year by removing abnormal portions of brain. Tissue from these resections is being analyzed for genetics and receptor abnormalities. Positron emission tomography and magnetic resonance imaging are being used to ferret out the origin of the patient's seizures.

Approximately 28,000 patients each year suffer a ruptured intracranial aneurysm. Approximately ten percent of these patients have a genetic predisposition to forming intracranial aneurysms. In conjunction with the Division of Neurology, we are screening candidate genes searching for the cause of intracranial aneurysms.

Current Appointments & Affiliations

Guy L. Odom Distinguished Professor of Neurosurgery, in the School of Medicine · 2001 - Present Neurosurgery, Neurosurgery
Professor of Neurosurgery · 1993 - Present Neurosurgery, Neurosurgery
Member of the Duke Cancer Institute · 1974 - Present Duke Cancer Institute, Institutes and Centers

Education, Training & Certifications

University of Illinois · 1974 M.D.