Scholars@Duke

• Background
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  Education, Training, & Certifications

  • M.D., University of North Carolina at Chapel Hill 1988
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  Duke Appointment History

  • Assistant Clinical Professor of Anesthesiology, Anesthesiology, Clinical Science Departments 2007 - 2010
  • Instructor, Temporary of Anesthesiology, Anesthesiology, Clinical Science Departments 2007
  • Assistant Consulting Professor of Anesthesiology, Anesthesiology, Cardiothoracic, Anesthesiology 2001 - 2006
  • Assistant Consulting Professor of Anesthesiology, Anesthesiology, Clinical Science Departments 1994 - 2001
• Publications & Artistic Works
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  Selected Publications

  • Academic Articles

    • Morris, J. J., D. P. Hamm, G. L. Pellom, A. Abd-Elfattah, and A. S. Wechsler. “Differential ventricular ischemic injury: an experimental model of right ventricular failure with a variable degree of left ventricular dysfunction.” J Thorac Cardiovasc Surg 96, no. 4 (October 1988): 590–99.
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    • Pasque, M. K., P. Van Trigt, G. L. Pellom, B. M. Freedman, and A. S. Wechsler. “Assessment of the intrinsic contractile status of the heart during sepsis by myocardial pressure-dimension analysis.” Ann Surg 208, no. 1 (July 1988): 110–17. https://doi.org/10.1097/00000658-198807000-00016.
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    • Morris, J. J., G. L. Pellom, C. E. Murphy, D. R. Salter, J. P. Goldstein, and A. S. Wechsler. “Quantification of the contractile response to injury: assessment of the work-length relationship in the intact heart.” Circulation 76, no. 3 (September 1987): 717–27. https://doi.org/10.1161/01.cir.76.3.717.
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    • Salter, D. R., G. L. Pellom, C. E. Murphy, L. A. Brunsting, J. P. Goldstein, J. M. Morris, and A. S. Wechsler. “Papillary-annular continuity and left ventricular systolic function after mital valve replacement.” Circulation 74, no. 3 II MONOGR. 123 (October 29, 1986): 121–29.
    • Morris, J. J., G. L. Pellom, D. P. Hamm, C. T. Everson, and A. S. Wechsler. “Dynamic right ventricular dimension. Relation to chamber volume during the cardiac cycle.” J Thorac Cardiovasc Surg 91, no. 6 (June 1986): 879–87.
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    • Morris, J. J., D. P. Hamm, G. L. Pellom, A. Abd-Elfattah, and A. S. Wechsler. “Right ventricular sensitivity to metabolic injury during cardiopulmonary bypass.” Arch Surg 121, no. 3 (March 1986): 338–44. https://doi.org/10.1001/archsurg.1986.01400030092016.
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    • Trigt, P. van, T. L. Spray, M. K. Pasque, R. B. Peyton, G. L. Pellom, and A. S. Wechsler. “The comparative effects of dopamine and dobutamine on ventricular mechanics after coronary artery bypass grafting: A pressure-dimension analysis.” Circulation 70, no. 3 II (October 25, 1984).
    • Freedman, B. M., M. K. Pasque, G. L. Pellom, D. W. Deaton, J. R. Frame, and A. S. Wechsler. “Effects of delay in administration of potassium cardioplegia to the isolated rat heart.” Ann Thorac Surg 37, no. 4 (April 1984): 309–13. https://doi.org/10.1016/s0003-4975(10)60736-9.
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    • Morris, J. J., D. P. Hamm, and G. L. Pellom. “A canine model of acute differential ventricular global ischemic injury.” Surgical Forum VOL. 35 (January 1, 1984): 331–34.
    • Van Trigt, P., C. C. Christian, L. Fagraeus, T. L. Spray, R. B. Peyton, G. L. Pellom, and A. S. Wechsler. “Myocardial depression by anesthetic agents (halothane, enflurane and nitrous oxide): quantitation based on end-systolic pressure-dimension relations.” Am J Cardiol 53, no. 1 (January 1, 1984): 243–47. https://doi.org/10.1016/0002-9149(84)90720-3.
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    • Pasque, M. K., C. E. Murphy, P. Van Trigt, G. L. Pellom, W. D. Currie, and A. S. Wechsler. “Myocardial adenosine triphosphate levels during early sepsis.” Arch Surg 118, no. 12 (December 1983): 1437–40. https://doi.org/10.1001/archsurg.1983.01390120057015.
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    • Van Trigt, P., C. C. Christian, L. Fagraeus, R. B. Peyton, R. N. Jones, T. L. Spray, M. K. Pasque, G. L. Pellom, and A. S. Wechsler. “The mechanism of halothane-induced myocardial depression. Altered diastolic mechanics versus impaired contractility.” J Thorac Cardiovasc Surg 85, no. 6 (June 1983): 832–38.
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    • Van Trigt, P., T. L. Spray, M. K. Pasque, R. B. Peyton, G. L. Pellom, C. M. Christian, L. Fagraeus, and A. S. Wechsler. “The influence of time on the response to dopamine after coronary artery bypass grafting: assessment of left ventricular performance and contractility using pressure/dimension analyses.” Ann Thorac Surg 35, no. 1 (January 1983): 3–13. https://doi.org/10.1016/s0003-4975(10)61424-5.
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    • Peyton, R. B., P. Van Trigt, G. L. Pellom, R. N. Jones, J. D. Sink, and A. S. Wechsler. “Improved tolerance to ischemia in hypertrophied myocardium by preischemic enhancement of adenosine triphosphate.” J Thorac Cardiovasc Surg 84, no. 1 (July 1982): 11–15.
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    • Van Trigt, P., T. L. Spray, M. K. Pasque, R. B. Peyton, G. L. Pellom, C. M. Christian, L. Fagraeus, and A. S. Wechsler. “The effect of PEEP on left ventricular diastolic dimensions and systolic performance following myocardial revascularization.” Ann Thorac Surg 33, no. 6 (June 1982): 585–92. https://doi.org/10.1016/s0003-4975(10)60817-x.
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    • Pasque, M. K., T. L. Spray, G. L. Pellom, P. Van Trigt, R. B. Peyton, W. D. Currie, and A. S. Wechsler. “Ribose-enhanced myocardial recovery following ischemia in the isolated working rat heart.” J Thorac Cardiovasc Surg 83, no. 3 (March 1982): 390–98.
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    • Van Trigt, P., R. N. Jones, C. O. Olsen, R. B. Peyton, W. D. Currie, G. L. Pellom, and A. S. Wechsler. “Sonomicrometric determination of ischemic contracture of the left ventricle.” J Thorac Cardiovasc Surg 83, no. 2 (February 1982): 298–305.
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    • Sink, J. D., G. L. Pellom, W. D. Currie, R. C. Hill, C. O. Olsen, R. N. Jones, and A. S. Wechsler. “Response of hypertrophied myocardium to ischemia: correlation with biochemical and physiological parameters.” J Thorac Cardiovasc Surg 81, no. 6 (June 1981): 865–72.
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    • Van Trigt, P., C. O. Olsen, G. L. Pellom, R. B. Peyton, R. N. Jones, J. Scott Rankin, and A. S. Wechsler. “The effect of verapamil on the diastolic mechanics of the left ventricle.” American Journal of Cardiology 47, no. 2 II (January 1, 1981): 411. https://doi.org/10.1016/0002-9149(81)90717-7.
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    • Sink, J. D., D. E. Attarian, W. R. Chitwood, R. C. Hill, G. L. Pellom, and A. S. Wechsler. “An improved technique for producing ventricular hypertrophy with a subcoronary valvular aortic stenosis model.” Ann Thorac Surg 30, no. 3 (September 1980): 285–90. https://doi.org/10.1016/s0003-4975(10)61259-3.
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    • Hill, R. C., G. L. Pellom, W. R. Chitwood, J. D. Sink, and A. S. Wechsler. “The relationship of transmural myocardial blood flow to midwall function.” J Surg Res 28, no. 4 (April 1980): 306–13. https://doi.org/10.1016/0022-4804(80)90090-6.
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    • Sink, J. D., W. D. Currie, G. L. Pellom, R. C. Hill, W. R. Chitwood, and A. S. Wechsler. “Correlation of mitochondrial function and ischemic contracture.” J Thorac Cardiovasc Surg 79, no. 4 (April 1980): 570–78.
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    • Sink, J. D., G. L. Pellom, W. D. Currie, W. R. Chitwood, R. C. Hill, and A. S. Wechsler. “Protection of mitochondrial function during ischemia by potassium cardioplegia: Correlation with ischemic contracture.” Circulation 60, no. 2 II (December 1, 1979).
    • Sink, J. D., A. S. Wechsler, G. L. Pellom, and W. M. Thompson. “Effect of B-15,000 (Iopamidol), a new nonionic contrast agent, on cardiac function of the isolated rat heart.” Invest Radiol 14, no. 6 (November 1979): 508–12. https://doi.org/10.1097/00004424-197911000-00011.
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    • Sink, J. D., G. L. Pellom, W. D. Currie, and A. S. Wechsler. “Relationship between ischemic contracture and mitochondrial function.” Surg Forum 29 (1978): 298–99.
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