Georgia Marie Beasley | Scholars@Duke

Georgia Marie Beasley
Assistant Professor of Surgery

Current Appointments & Affiliations

Assistant Professor of Surgery, Surgery, Advanced Oncologic and Gastrointestinal Surgery, Surgery 2017
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2017

Contact Information

Dept Of Surgery, Durham, NC 27710
Erwin Rd, Durham, NC 27710
georgia.beasley@duke.edu (919) 684-8111

Background
Education, Training, & Certifications
- Surgical Oncology Fellow, Surgery, Ohio State University 2015 - 2017
- General Surgery Resident, Surgery, Duke University 2008 - 2015
- M.H.S., Duke University 2012
- M.D., Duke University School of Medicine 2008
- B.A., Duke University 2001
Publications & Artistic Works
Selected Publications
- Books
  - Beasley, GM, and Olson, JA. What's new in neoadjuvant therapy for breast cancer?. January 2010. Full Text
- Book Sections
  - Beasley, G, and Blazer, DG. "Hepatic abscess." In Contemporary Surgical Management of Liver, Biliary Tract, and Pancreatic Disease, 35-46. January 1, 2013. Full Text
- Journal Articles
  - Beasley, GM, Hu, Y, Youngwirth, L, Scheri, RP, Salama, AK, Rossfeld, K, Gardezi, S, Agnese, DM, Howard, JH, Tyler, DS, Slingluff, CL, and Terando, AM. "Sentinel Lymph Node Biopsy for Recurrent Melanoma: A Multicenter Study." Annals of surgical oncology 24, no. 9 (September 2017): 2728-2733. Full Text
  - Kurtz, J, Beasley, GM, Agnese, D, Kendra, K, Olencki, TE, Terando, A, and Howard, JH. "Surveillance strategies in the follow-up of melanoma patients: too much or not enough?." The Journal of surgical research 214 (June 2017): 32-37. Full Text
  - Turner, MC, Rossfeld, K, Salama, AKS, Tyler, D, and Beasley, G. "Can binimetinib, encorafenib and masitinib be more efficacious than currently available mutation-based targeted therapies for melanoma treatment?." Expert opinion on pharmacotherapy 18, no. 5 (April 2017): 487-495. (Review) Full Text
  - Beasley, GM, Kurtz, J, Vandeusen, J, Howard, JH, Terando, A, Agnese, D, Liebner, D, Jeter, J, and Olencki, T. "Immune Checkpoint Inhibitor Therapy as a Novel and Effective Therapy for Aggressive Cutaneous Squamous-cell Carcinoma." Clinical Skin Cancer 1, no. 2 (April 2016): 75-81. Full Text
  - Brys, AK, Bhatti, L, Bashir, MR, Jaffe, TA, Beasley, GM, Nath, NS, Salama, AKS, Tyler, DS, and Mosca, PJ. "Computed Tomography-Based Limb Volume Measurements for Isolated Limb Infusion in Melanoma." Annals of surgical oncology 23, no. 4 (April 2016): 1090-1095. Full Text
  - Beasley, GM, Pappas, TN, and Kirk, AD. "Procedure Delegation by Attending Surgeons Performing Concurrent Operations in Academic Medical Centers: Balancing Safety and Efficiency." Annals of surgery 261, no. 6 (June 2015): 1044-1045. Full Text
  - Beasley, G, and Tyler, D. "In-transit melanoma metastases: incidence, prognosis, and the role of lymphadenectomy." Annals of surgical oncology 22, no. 2 (February 2015): 358-360. Full Text
  - Muilenburg, DJ, Beasley, GM, Thompson, ZJ, Lee, J-H, Tyler, DS, and Zager, JS. "Burden of disease predicts response to isolated limb infusion with melphalan and actinomycin D in melanoma." Annals of surgical oncology 22, no. 2 (February 2015): 482-488. Full Text
  - Turley, RS, Tokuhisa, Y, Toshimitsu, H, Lidsky, ME, Padussis, JC, Fontanella, A, Deng, W, Augustine, CK, Beasley, GM, Davies, MA, Dewhirst, MW, and Tyler, DS. "Targeting N-cadherin increases vascular permeability and differentially activates AKT in melanoma." Annals of surgery 261, no. 2 (February 2015): 368-377. Full Text
  - Beasley, GM, Speicher, P, Augustine, CK, Dolber, PC, Peterson, BL, Sharma, K, Mosca, PJ, Royal, R, Ross, M, Zager, JS, and Tyler, DS. "A Multicenter Phase I Dose Escalation Trial to Evaluate Safety and Tolerability of Intra-arterial Temozolomide for Patients with Advanced Extremity Melanoma Using Normothermic Isolated Limb Infusion." Annals of Surgical Oncology 22, no. 1 (January 1, 2015): 287-294. Full Text
  - Jiang, BS, Beasley, GM, Speicher, PJ, Mosca, PJ, Morse, MA, Hanks, B, Salama, A, and Tyler, DS. "Immunotherapy following regional chemotherapy treatment of advanced extremity melanoma." Annals of surgical oncology 21, no. 8 (August 2014): 2525-2531. Full Text
  - Beasley, GM, Ostbye, T, Muhlbaier, LH, Foley, C, Scarborough, J, Turley, RS, and Shapiro, ML. "Age and gender differences in substance screening may underestimate injury severity: a study of 9793 patients at level 1 trauma center from 2006 to 2010." J Surg Res 188, no. 1 (May 1, 2014): 190-197. Full Text Link to Item
  - Beasley, GM, Ostbye, T, Muhlbaier, LH, Foley, C, Scarborough, J, Turley, RS, and Shapiro, ML. "Age and gender differences in substance screening may underestimate injury severity: A study of 9793 patients at level 1 trauma center from 2006 to 2010." Journal of Surgical Research 188, no. 1 (May 1, 2014): 190-197. Full Text
  - Speicher, PJ, Beasley, GM, Jiang, B, Lidsky, ME, Palmer, GM, Scarbrough, PM, Mosca, PJ, Dewhirst, MW, and Tyler, DS. "Hypoxia in melanoma: using optical spectroscopy and EF5 to assess tumor oxygenation before and during regional chemotherapy for melanoma." Ann Surg Oncol 21, no. 5 (May 2014): 1435-1440. Full Text Link to Item
  - "Discussion." Journal of the American College of Surgeons 218, no. 4 (April 2014): 692-694. Full Text
  - Beasley, GM, Speicher, P, Sharma, K, Seigler, H, Salama, A, Mosca, P, and Tyler, DS. "Efficacy of repeat sentinel lymph node biopsy in patients who develop recurrent melanoma." Journal of the American College of Surgeons 218, no. 4 (April 2014): 686-692. Full Text
  - Tokuhisa, Y, Lidsky, ME, Toshimitsu, H, Turley, RS, Beasley, GM, Ueno, T, Sharma, K, Augustine, CK, and Tyler, DS. "SRC family kinase inhibition as a novel strategy to augment melphalan-based regional chemotherapy of advanced extremity melanoma." Ann Surg Oncol 21, no. 3 (March 2014): 1024-1030. Full Text Link to Item
  - Tokuhisa, Y, Lidsky, ME, Toshimitsu, H, Turley, RS, Beasley, GM, Ueno, T, Sharma, K, Augustine, CK, and Tyler, DS. "Src family kinase inhibition as a novel strategy to augment melphalan-based regional chemotherapy of advanced extremity melanoma." Annals of Surgical Oncology 21, no. 3 (March 1, 2014): 1024-1030. Full Text
  - Wong, J, Ann Chen, Y, Fisher, KJ, Beasley, GM, Tyler, DS, and Zager, JS. "Resection of residual disease after isolated limb infusion (ILI) is equivalent to a complete response after ili-alone in advanced extremity melanoma." Annals of Surgical Oncology 21, no. 2 (February 1, 2014): 650-655. Full Text
  - Beasley, GM, Speicher, P, Sharma, K, Seigler, H, Salama, A, Mosca, P, and Tyler, DS. "Efficacy of repeat sentinel lymph node biopsy in patients who develop recurrent melanoma." Journal of the American College of Surgeons 218, no. 4 (January 1, 2014): 686-692. Full Text
  - Jiang, BS, Beasley, GM, Speicher, PJ, Mosca, PJ, Morse, MA, Hanks, B, Salama, A, and Tyler, DS. "Immunotherapy following regional chemotherapy treatment of advanced extremity melanoma." Annals of Surgical Oncology 21, no. 8 (January 1, 2014): 2525-2531. Full Text
  - Speicher, PJ, Beasley, GM, Jiang, B, Lidsky, ME, Palmer, GM, Scarbrough, PM, Mosca, PJ, Dewhirst, MW, and Tyler, DS. "Hypoxia in melanoma: Using optical spectroscopy and EF5 to assess tumor oxygenation before and during regional chemotherapy for melanoma." Annals of Surgical Oncology 21, no. 5 (January 1, 2014): 1435-1440. Full Text
  - Hanks, BA, Holtzhausen, A, Evans, KS, Jamieson, R, Gimpel, P, Campbell, OM, Hector-Greene, M, Sun, L, Tewari, A, George, A, Starr, M, Nixon, A, Augustine, C, Beasley, G, Tyler, DS, Osada, T, Morse, MA, Ling, L, Lyerly, HK, and Blobe, GC. "Type III TGF-β receptor downregulation generates an immunotolerant tumor microenvironment." J Clin Invest 123, no. 9 (September 2013): 3925-3940. Full Text Open Access Copy Link to Item
  - Augustine, CK, Freedman, JA, Beasley, GM, and Tyler, DS. "Melanoma." 2 (August 29, 2013): 765-775. (Chapter) Full Text
  - Lidsky, ME, Turley, RS, Beasley, GM, Sharma, K, and Tyler, DS. "Predicting disease progression after regional therapy for in-transit melanoma." JAMA surgery 148, no. 6 (June 2013): 493-498. Full Text
  - Shetty, G, Beasley, GM, Sparks, S, Barfield, M, Masoud, M, Mosca, PJ, Pruitt, SK, Salama, AKS, Chan, C, Tyler, DS, and Weinhold, KJ. "Plasma cytokine analysis in patients with advanced extremity melanoma undergoing isolated limb infusion." Ann Surg Oncol 20, no. 4 (April 2013): 1128-1135. Full Text Link to Item
  - Li, GZ, Sloane, JL, Lidsky, ME, Beasley, GM, Reddy, SK, Scarborough, JE, Tyler, DS, Turley, RS, and Clary, BM. "Simultaneous diaphragm and liver resection: a propensity-matched analysis of postoperative morbidity." J Am Coll Surg 216, no. 3 (March 2013): 402-411. Full Text Link to Item
  - Wong, J, Ann Chen, Y, Fisher, KJ, Beasley, GM, Tyler, DS, and Zager, JS. "Resection of Residual Disease after Isolated Limb Infusion (ILI) Is Equivalent to a Complete Response after ILI-Alone in Advanced Extremity Melanoma." Annals of Surgical Oncology (2013): 1-6.
  - Beasley, GM, Sharma, K, Wong, J, Miller, M, Turley, RS, Lidsky, M, Masoud, M, Dewhirst, MW, Mosca, PJ, Zager, JS, and Tyler, DS. "A multi-institution experience comparing the clinical and physiologic differences between upper extremity and lower extremity melphalan-based isolated limb infusion." Cancer 118, no. 24 (December 2012): 6136-6143. Full Text
  - Beasley, GM, Coleman, AP, Raymond, A, Sanders, G, Selim, MA, Peterson, BL, Brady, MS, Davies, MA, Augustine, C, and Tyler, DS. "A phase I multi-institutional study of systemic sorafenib in conjunction with regional melphalan for in-transit melanoma of the extremity." Ann Surg Oncol 19, no. 12 (November 2012): 3896-3905. Full Text Link to Item
  - Beasley, GM, Parsons, C, Broadwater, G, Selim, MA, Marzban, S, Abernethy, AP, Salama, AKS, Eikman, EA, Wong, T, Zager, JS, and Tyler, DS. "A multicenter prospective evaluation of the clinical utility of F-18 FDG-PET/CT in patients with AJCC stage IIIB or IIIC extremity melanoma." Ann Surg 256, no. 2 (August 2012): 350-356. Full Text Link to Item
  - Sharma, K, Beasley, G, Turley, R, Raymond, AK, Broadwater, G, Peterson, B, Mosca, P, and Tyler, D. "Patterns of recurrence following complete response to regional chemotherapy for in-transit melanoma." Annals of surgical oncology 19, no. 8 (August 2012): 2563-2571. Full Text
  - Turley, RS, Fontanella, AN, Padussis, JC, Toshimitsu, H, Tokuhisa, Y, Cho, EH, Hanna, G, Beasley, GM, Augustine, CK, Dewhirst, MW, and Tyler, DS. "Bevacizumab-induced alterations in vascular permeability and drug delivery: a novel approach to augment regional chemotherapy for in-transit melanoma." Clin Cancer Res 18, no. 12 (June 15, 2012): 3328-3339. Full Text Link to Item
  - "Correction." Journal of the American College of Surgeons 214, no. 2 (February 2012): 245-245. Full Text
  - Chai, CY, Deneve, JL, Beasley, GM, Marzban, SS, Chen, YA, Rawal, B, Grobmyer, SR, Hochwald, SN, Tyler, DS, and Zager, JS. "A multi-institutional experience of repeat regional chemotherapy for recurrent melanoma of extremities." Annals of Surgical Oncology 19, no. 5 (2012): 1637-1643. Full Text
  - Beasley, GM, and Tyler, DS. "Treatment of in-transit melanoma: an opportunity to discover critical knowledge." Oncology (Williston Park) 25, no. 14 (December 2011): 1351-1355. Link to Item
  - Raymond, AK, Beasley, GM, Broadwater, G, Augustine, CK, Padussis, JC, Turley, R, Peterson, B, Seigler, H, Pruitt, SK, and Tyler, DS. "Current trends in regional therapy for melanoma: lessons learned from 225 regional chemotherapy treatments between 1995 and 2010 at a single institution." J Am Coll Surg 213, no. 2 (August 2011): 306-316. Full Text Link to Item
  - Beasley, GM, Riboh, JC, Augustine, CK, Zager, JS, Hochwald, SN, Grobmyer, SR, Peterson, B, Royal, R, Ross, MI, and Tyler, DS. "Prospective multicenter phase II trial of systemic ADH-1 in combination with melphalan via isolated limb infusion in patients with advanced extremity melanoma." J Clin Oncol 29, no. 9 (March 20, 2011): 1210-1215. Full Text Link to Item
  - Beasley, GM, and Tyler, DS. "Standardizing regional therapy: Developing a consensus on optimal utilization of regional chemotherapy treatments in Melanoma." Annals of Surgical Oncology 18, no. 7 (2011): 1814-1818. Full Text
  - Han, D, Beasley, GM, Tyler, DS, and Zager, JS. "Minimally invasive intra-arterial regional therapy for metastatic melanoma: Isolated limb infusion and percutaneous hepatic perfusion." Expert Opinion on Drug Metabolism and Toxicology 7, no. 11 (2011): 1383-1394. Full Text
  - Turaga, KK, Beasley, GM, III, JMK, Delman, KA, Grobmyer, SR, Gonzalez, RJ, Letson, GD, Cheong, D, Tyler, DS, and Zager, JS. "Limb preservation with isolated limb infusion for locally advanced nonmelanoma cutaneous and soft-tissue malignant neoplasms." Archives of Surgery 146, no. 7 (2011): 870-875. Full Text
  - Augustine, CK, Toshimitsu, H, Jung, S-H, Zipfel, PA, Yoo, JS, Yoshimoto, Y, Selim, MA, Burchette, J, Beasley, GM, McMahon, N, Padussis, J, Pruitt, SK, Ali-Osman, F, and Tyler, DS. "Sorafenib, a multikinase inhibitor, enhances the response of melanoma to regional chemotherapy." Mol Cancer Ther 9, no. 7 (July 2010): 2090-2101. Full Text Link to Item
  - Coleman, A, Augustine, CK, Beasley, G, Sanders, G, and Tyler, D. "Optimizing regional infusion treatment strategies for melanoma of the extremities." Expert Rev Anticancer Ther 9, no. 11 (November 2009): 1599-1609. (Review) Full Text Link to Item
  - Beasley, GM, McMahon, N, Sanders, G, Augustine, CK, Selim, MA, Peterson, B, Norris, R, Peters, WP, Ross, MI, and Tyler, DS. "A phase 1 study of systemic ADH-1 in combination with melphalan via isolated limb infusion in patients with locally advanced in-transit malignant melanoma." Cancer 115, no. 20 (October 15, 2009): 4766-4774. Full Text Link to Item
  - Santillan, AA, Delman, KA, Beasley, GM, Mosca, PJ, Hochwald, SN, Grobmyer, SR, Andtbacka, RH, Noyes, RD, Kane, JM, Ross, MI, Tyler, DS, and Zager, JS. "Predictive factors of regional toxicity and serum creatine phosphokinase levels after isolated limb infusion for melanoma: a multi-institutional analysis." Ann Surg Oncol 16, no. 9 (September 2009): 2570-2578. Full Text Link to Item
  - Ceppa, EP, Sileshi, B, Beasley, GM, and Lawson, JH. "Surgical excision of infected arteriovenous grafts: technique and review." J Vasc Access 10, no. 3 (July 2009): 148-152. (Review) Link to Item
  - Beasley, GM, Caudle, A, Petersen, RP, McMahon, NS, Padussis, J, Mosca, PJ, Zager, JS, Hochwald, SN, Grobmyer, SR, Delman, KA, Andtbacka, RH, Noyes, RD, Kane, JM, Seigler, H, Pruitt, SK, Ross, MI, and Tyler, DS. "A multi-institutional experience of isolated limb infusion: defining response and toxicity in the US." J Am Coll Surg 208, no. 5 (May 2009): 706-715. Full Text Link to Item
  - Beasley, GM, and Tyler, DS. "Optimizing regional therapy for melanoma." Ann Surg Oncol 16, no. 5 (May 2009): 1095-1097. Full Text Link to Item
  - McMahon, N, Cheng, TY, Beasley, GM, Spasojevic, I, Petros, W, Augustine, CK, Zipfel, P, Padussis, JC, Sanders, G, and Tyler, DS. "Optimizing melphalan pharmacokinetics in regional melanoma therapy: does correcting for ideal body weight alter regional response or toxicity?." Ann Surg Oncol 16, no. 4 (April 2009): 953-961. Full Text Link to Item
  - Beasley, GM, Kahn, L, and Tyler, DS. "Current clinical and research approaches to optimizing regional chemotherapy: novel strategies generated through a better understanding of drug pharmacokinetics, drug resistance, and the development of clinically relevant animal models." Surg Oncol Clin N Am 17, no. 4 (October 2008): 731-viii. (Review) Full Text Link to Item
  - Beasley, GM, Petersen, RP, Yoo, J, McMahon, N, Aloia, T, Petros, W, Sanders, G, Cheng, T-Y, Pruitt, SK, Seigler, H, and Tyler, DS. "Isolated limb infusion for in-transit malignant melanoma of the extremity: a well-tolerated but less effective alternative to hyperthermic isolated limb perfusion." Ann Surg Oncol 15, no. 8 (August 2008): 2195-2205. Full Text Link to Item
  - Beasley, GM, Ross, MI, and Tyler, DS. "Future directions in regional treatment strategies for melanoma and sarcoma." Int J Hyperthermia 24, no. 3 (May 2008): 301-309. (Review) Full Text Link to Item

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Education, Training, & Certifications

Selected Publications

Books

Book Sections

Journal Articles