Guido Ferrari
Professor in Surgery
The activities of the Ferrari Laboratory are based on both independent basic research and immune monitoring studies. The research revolves around three main areas of interest: class I-mediated cytotoxic CD8+ T cell responses, antibody-dependent cellular cytotoxicity (ADCC), gene expression in NK and T cellular subsets upon infection with HIV-1. With continuous funding over the last 11 years from the NIH and Bill & Melinda Gates Foundation along with many other productive collaborations within and outside of Duke, the Ferrari Lab has expanded its focus of research to include the ontogeny of HIV-1 specific immune responses that work by eliminating HIV-1 infected cells and how these can be induced by AIDS vaccine candidates.
Office Hours
Saturday and Sunday upon request
Current Appointments & Affiliations
- Professor in Surgery, Surgery, Surgical Sciences, Surgery 2021
- Research Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2021
- Member of the Duke Human Vaccine Institute, Duke Human Vaccine Institute, Institutes and Centers 2009
- Affiliate, Duke Global Health Institute, Duke Global Health Institute, University Institutes and Centers 2009
Contact Information
- 915 S. Lasalle Street, Sorf Building Room 208, Durham, NC 27710
- Box 2926 Med Ctr, Durham, NC 27710
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gflmp@duke.edu
(919) 684-2862
- Background
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Education, Training, & Certifications
- M.D., University of Genoa (Italy) 1985
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Previous Appointments & Affiliations
- Associate Professor of Surgery, Surgery, Surgical Sciences, Surgery 2013 - 2020
- Associate Research Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2014 - 2020
- Assistant Professor of Surgery, Surgery, Surgical Sciences, Surgery 2006 - 2013
- Assistant Research Professor in Surgery, Surgery, Surgical Sciences, Surgery 2001 - 2006
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Academic Positions Outside Duke
- Honorary Professor, University of Cape Town. 2019 - 2024
- Adjunct Visiting Professor, University of Cape Town. 2012 - 2019
- Recognition
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In the News
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OCT 11, 2022 Duke Health News -
NOV 19, 2019 -
NOV 27, 2018
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- Expertise
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Subject Headings
- AIDS Vaccines
- Acute Disease
- Adenoviridae
- Adjuvants, Immunologic
- Administration, Mucosal
- Adolescent
- Adult
- Africa
- African Americans
- Aged
- Aged, 80 and over
- Alleles
- Amino Acid Sequence
- Amino Acid Substitution
- Animals
- Anti-HIV Agents
- Antibodies, Monoclonal
- Antibodies, Neutralizing
- Antibodies, Viral
- Antibody Affinity
- Antibody Formation
- Antibody Specificity
- Antibody-Dependent Cell Cytotoxicity
- Antigenic Variation
- Antigens, CD
- Antigens, CD4
- Antigens, CD8
- Antigens, Differentiation, T-Lymphocyte
- Antigens, Viral
- Antiretroviral Therapy, Highly Active
- Antiviral Agents
- Apoptosis Regulatory Proteins
- Autoantibodies
- Avipoxvirus
- B cells
- B-Lymphocytes
- Base Sequence
- Binding, Competitive
- Biological Markers
- Biological Specimen Banks
- Biopsy
- CD4 Lymphocyte Count
- CD4-CD8 Ratio
- CD4-Positive T-Lymphocytes
- CD8-Positive T-Lymphocytes
- Canarypox virus
- Case-Control Studies
- Cell Line
- Cell Proliferation
- Cell Survival
- Cells, Cultured
- Chemokine CCL2
- Child
- Chronic Disease
- Clinical Trials as Topic
- Clinical trials
- Clone Cells
- Cohort Studies
- Colostrum
- Combined Modality Therapy
- Conserved Sequence
- Cross Reactions
- Cross-Sectional Studies
- Cryopreservation
- Cytidine Deaminase
- Cytokines
- Cytotoxicity Tests, Immunologic
- Cytotoxicity, Immunologic
- DNA, Viral
- Defective Viruses
- Disease Models, Animal
- Disease Susceptibility
- Double-Blind Method
- Down-Regulation
- Drug Therapy, Combination
- Enzyme-Linked Immunosorbent Assay
- Enzyme-Linked Immunospot Assay
- Epitope Mapping
- Epitopes
- Epitopes, B-Lymphocyte
- Epitopes, T-Lymphocyte
- Ethiopia
- Evolution, Molecular
- Fas Ligand Protein
- Flow Cytometry
- Fluorescent Antibody Technique, Indirect
- Founder Effect
- Gene Expression Regulation, Viral
- Gene Products, env
- Gene Products, gag
- Gene Rearrangement, T-Lymphocyte
- Genes, Immunoglobulin Heavy Chain
- Genes, Viral
- Genes, tat
- Genetic Fitness
- Genetic Vectors
- Genome, Viral
- Glycoproteins
- Granulocyte-Macrophage Colony-Stimulating Factor
- Granzymes
- HIV
- HIV Antibodies
- HIV Antigens
- HIV Envelope Protein gp120
- HIV Envelope Protein gp160
- HIV Envelope Protein gp41
- HIV Infections
- HIV Protease Inhibitors
- HIV Reverse Transcriptase
- HIV Seronegativity
- HIV-1
- HLA Antigens
- HLA-A Antigens
- HLA-A2 Antigen
- HLA-B Antigens
- HLA-B27 Antigen
- Helper Viruses
- Hematopoietic Stem Cells
- Hemocyanin
- High-Throughput Screening Assays
- Human Experimentation
- Humans
- Immune Evasion
- Immune Sera
- Immune System
- Immune Tolerance
- Immunity
- Immunity, Cellular
- Immunity, Innate
- Immunity, Mucosal
- Immunization
- Immunization Schedule
- Immunization, Secondary
- Immunodominant Epitopes
- Immunoglobulin A
- Immunoglobulin G
- Immunoglobulin Variable Region
- Immunohistochemistry
- Immunologic Memory
- Immunologic Tests
- Immunophenotyping
- Immunotherapy
- Infant
- Infant, Newborn
- Interferon-gamma
- Interferon-gamma Release Tests
- Interleukin-15
- Interleukin-7
- International Cooperation
- Intestines
- Killer Cells, Lymphokine-Activated
- Killer Cells, Natural
- Kinetics
- Laboratories
- Lactation
- Latent Tuberculosis
- Leukocytes
- Leukocytes, Mononuclear
- Linear Models
- Liposomes
- Logistic Models
- Longitudinal Studies
- Lymph Nodes
- Lymphocyte Activation
- Lymphocyte Count
- Lymphocyte Subsets
- Lymphocytic Choriomeningitis
- Macaca
- Macaca mulatta
- Malaria Vaccines
- Membrane Fusion
- Membrane Glycoproteins
- Membrane Proteins
- Middle Aged
- Milk, Human
- Models, Genetic
- Models, Molecular
- Molecular Docking Simulation
- Molecular Sequence Data
- Mucous Membrane
- Multivariate Analysis
- Mutation
- Mycobacterium bovis
- Mycobacterium tuberculosis
- Neutralization Tests
- Odds Ratio
- Peptides
- Perforin
- Phenotype
- Plasma
- Plasmids
- Pregnancy
- Pregnancy Complications, Infectious
- Program Development
- Program Evaluation
- Programmed Cell Death 1 Receptor
- Prospective Studies
- Protease Inhibitors
- Protein Binding
- Protein Conformation
- Proteins
- Quality Control
- Quality Indicators, Health Care
- RNA, Viral
- RNA-Binding Proteins
- RNA-Directed DNA Polymerase
- Receptors, CCR5
- Receptors, IgG
- Receptors, Interleukin-2
- Receptors, Tumor Necrosis Factor, Type II
- Receptors, Virus
- Recombinant Proteins
- Regression Analysis
- Reproducibility of Results
- SAIDS Vaccines
- Selection, Genetic
- Sequence Analysis, Protein
- Simian Acquired Immunodeficiency Syndrome
- Simian immunodeficiency virus
- Single-Cell Analysis
- Software
- Specimen Handling
- Staining and Labeling
- Standardization
- Statistics, Nonparametric
- Suppressor Factors, Immunologic
- Surface Plasmon Resonance
- T cells
- T-Cell Antigen Receptor Specificity
- T-Lymphocyte Subsets
- T-Lymphocytes
- T-Lymphocytes, Cytotoxic
- Tetanus Toxoid
- Thymus Gland
- Transcription, Genetic
- Treatment Failure
- Treatment Outcome
- Tuberculin Test
- Tuberculosis
- Vaccination
- Vaccines, Attenuated
- Vaccines, DNA
- Vaccines, Subunit
- Vaccines, Synthetic
- Vaccinia virus
- Vagina
- Viral Envelope Proteins
- Viral Load
- Viral Proteins
- Viral Tropism
- Viral Vaccines
- Viremia
- Virion
- Virus Replication
- Workflow
- Young Adult
- env Gene Products, Human Immunodeficiency Virus
- gag Gene Products, Human Immunodeficiency Virus
- rev Gene Products, Human Immunodeficiency Virus
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Global Scholarship
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Research
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- Research
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Selected Grants
- SOSIP-NP/mRNA combination for novel preventive and therapeutic HIV-1 vaccine regimens awarded by National Institutes of Health 2022 - 2027
- Medical Scientist Training Program awarded by National Institutes of Health 2022 - 2027
- Early life B cell responses and inflammation following SARS-CoV-2 infection awarded by National Institutes of Health 2021 - 2026
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2025
- EQAPOL - Years 2017 to 2024 - BASE awarded by National Institutes of Health 2017 - 2024
- Modulation of Antigen Presenting Cell Function by HIV Vaccine induced Antibodies awarded by Triangle Community Foundation 2023 - 2024
- 17th INTERNATIONAL CONFERENCE ON HIV TREATMENT, PATHOGENESIS, AND PREVENTION RESEARCH (INTEREST) awarded by National Institutes of Health 2023 - 2024
- Synthetic DNA launched & adjuvanted Immune Focused Env immunogens for HIV awarded by Wistar Institute of Anatomy and Biology 2022 - 2023
- HVTN Supplement 2022 awarded by Fred Hutchinson Cancer Center 2022 - 2023
- HVTN LC awarded by Fred Hutchinson Cancer Center 2022 - 2023
- HVTN Laboratory Center: Phase 1 PF awarded by Fred Hutchinson Cancer Center 2022 - 2023
- CIVICS Component A - Option 3 awarded by National Institutes of Health 2019 - 2023
- Early life B cell responses and inflammation following SARS-CoV-2 infection awarded by Weill Cornell Medicine 2022 - 2023
- Targeting the HIV-1 reservoir with a combination of an IDLV-SIVGag therapeutic vaccine and Fc-engineered bnAbs (R01) awarded by National Institutes of Health 2020 - 2023
- New Analytic Approaches and Endpoints in Human HIV Vaccine Correlate Studies awarded by Dartmouth College 2022 - 2023
- Collaboratory of AIDS Researchers for Eradication (CARE) awarded by University of North Carolina - Chapel Hill 2021 - 2023
- Collaboratory of AIDS Researchers for Eradication (CARE) awarded by University of North Carolina - Chapel Hill 2021 - 2023
- 2022 International Conference on HIV Treatment, Pathogenesis, and Prevention Research (INTEREST) awarded by National Institutes of Health 2022 - 2023
- Infectious Diseases in Africa: Correlates of Protection, Lessons from Vaccines and Natural Infection Studies awarded by National Institutes of Health 2020 - 2023
- HVTN 705 Case Control Janssen awarded by Fred Hutchinson Cancer Center 2021 - 2022
- CoVPN 3001 A Phase 3, Randomized, Stratified, Observer-Blind, Placebo-Controlled Study to Evaluate the Efficacy, Safety, and Immunogenicity of mRNA-1273 SARS-CoV-2 Vaccine awarded by Fred Hutchinson Cancer Center 2022
- CoVPN 3003 A Phase 3 Study to Assess the Efficacy and Safety of Ad26.COV2.S for the Prevention of SARS-CoV-2-mediated COVID-19 in Adults Aged 18 Years and Older awarded by Seattle Cancer Care Alliance 2022
- CoVPN 3005: Efficacy, Immunogenicity, and Safety of Two SARS-CoV-2 Recombinant Protein Vaccines with Adjuvant in Adults 18 Years of Age and Older awarded by Seattle Cancer Care Alliance 2022
- CoVPN 5001 A Prospective Study of Acute Immune Responses to SARS-CoV-2 Infection awarded by Fred Hutchinson Cancer Center 2022
- HVTN 405/HPTN 1901 (CoVPN) Characterizing SARS-CoV-2-specific Immunity in Convalescent Individuals awarded by Fred Hutchinson Cancer Center 2022
- In vitro characterization of antibody-dependent cellular mediated cytotoxic responses against SARS-CoV-2 awarded by St. Jude Children's Research Hospital 2021 - 2022
- Impact of Fc N-glycan structure on HIV-specific antibody functions awarded by University of Wyoming 2016 - 2022
- CARE Focus 2: Clearance of HIV Antigen-Positive Cells awarded by University of North Carolina - Chapel Hill 2016 - 2022
- HVTN Laboratory Center: Phase 1 PF awarded by Fred Hutchinson Cancer Research Center 2020 - 2022
- HVTN 405/HPTN 1901 (CoVPN) Characterizing SARS-CoV-2-specific Immunity in Convalescent Individuals awarded by Fred Hutchinson Cancer Research Center 2020 - 2022
- Combined Hepatitis B and HIV-1 Envelope Infant Vaccination to Augment T cell Help through Enhanced Linked Recognition awarded by National Institutes of Health 2017 - 2022
- Project 2: Synthetic DNA & Novel Env Vaccine for HIV awarded by Wistar Institute of Anatomy and Biology 2015 - 2022
- Seraworx - EQAPOL ELISPOT SRA awarded by Seraworx 2021
- HVTN 705 Pilot awarded by Fred Hutchinson Cancer Research Center 2020 - 2021
- MGD020 IND enabling studies awarded by MacroGenics, Inc. 2020 - 2021
- CARE Focus 1: Latency Biomarker Project awarded by University of North Carolina - Chapel Hill 2018 - 2021
- Primate Contract Expansion for Covid-19 awarded by National Institutes of Health 2020 - 2021
- 14th International Conference on HIV Treatment, Pathogenesis, and Prevention Research (INTEREST 2020) awarded by National Institutes of Health 2020 - 2021
- Protocol Development Assays awarded by Fred Hutchinson Cancer Research Center 2019 - 2020
- HVTN Laboratory Center: HVTN Phase 1 awarded by Fred Hutchinson Cancer Research Center 2015 - 2020
- HVTN Laboratory Center: HVTN 118 awarded by Fred Hutchinson Cancer Research Center 2006 - 2020
- 13th International Conference on HIV Treatment, Pathogenesis, and Prevention Research (Interest) awarded by National Institutes of Health 2019 - 2020
- Infectious Diseases in Africa: Immune Escape and HIV Vaccines awarded by National Institutes of Health 2009 - 2020
- Exploring Dual-Affinity Re-Targeting Proteins for Cure of Pediatric HIV-1 Infection awarded by National Institutes of Health 2016 - 2019
- Creation of a bnAbnectin awarded by ViiV Healthcare 2017 - 2019
- IGM Proposal awarded by IGM Biosciences, Inc. 2016 - 2019
- 2018 INTEREST Conference awarded by National Institutes of Health 2018 - 2019
- HIV Vaccine Trials Network: LC P5 PF awarded by Fred Hutchinson Cancer Research Center 2015 - 2018
- HVTN - A004 awarded by Fred Hutchinson Cancer Research Center 2015 - 2018
- Evaluation of the host immune response and viral molecular phenotype in lung transplant recipients with PTLD awarded by Mount Sinai School of Medicine 2017 - 2018
- CARE Duke-UNC Latency Biomarker Supplement Year 2 awarded by University of North Carolina - Chapel Hill 2016 - 2018
- 2017 INTEREST Conference awarded by National Institutes of Health 2017 - 2018
- Nonhuman Primate Core-Option 6 awarded by National Institutes of Health 2012 - 2018
- EQAPOL - Option 6 - 2016 to 2017 - ELISPOT awarded by National Institutes of Health 2010 - 2017
- EQAPOL Option 5 awarded by National Institutes of Health 2010 - 2017
- Focus 1: Detection of HIV Antigen-Positive Cells awarded by University of North Carolina - Chapel Hill 2016 - 2017
- Invitro Function of DART Molecules (Base) awarded by MacroGenics, Inc. 2016 - 2017
- Infant immune correlates of perinatal mother to child transmission of HIV awarded by National Institutes of Health 2015 - 2017
- Intervening with Latent HIV-1 Infection using Gnidimacrin awarded by National Institutes of Health 2014 - 2017
- 10th INTEREST Workshop on HIV awarded by National Institutes of Health 2016 - 2017
- HIV Vaccine Trials Network: LC P5 PF awarded by Fred Hutchinson Cancer Research Center 2014 - 2015
- LC: HIV Vaccine Trials Network: Phase 1 PF awarded by Fred Hutchinson Cancer Research Center 2014 - 2015
- HIV Envelope-specific functional antibody responses in HIV-exposed, HIV-vaccinated infants awarded by National Institutes of Health 2012 - 2015
- HIV-1 Gene Suppression by CD8+ T Cells awarded by National Institutes of Health 2002 - 2015
- AIDS International Training and Research Program awarded by National Institutes of Health 2003 - 2014
- Poly-functional analyses of vaccine-induced T cell responses awarded by National Institutes of Health 2001 - 2012
- Correlates of Vaccine Protection Workshop awarded by National Institutes of Health 2010 - 2011
- International Clinical Trials Unit awarded by National Institutes of Health 2004 - 2009
- Infectious Diseases in Africa: Measurement of Immune Responses awarded by National Institutes of Health 2007 - 2008
- Central Laboratory for the HIV Vaccines Trial Network awarded by National Institutes of Health 2000 - 2006
- NCRR FACSAria Cell Sorter awarded by National Center for Research Resources 2004 - 2006
- Anti-Hiv Ctl And Hiv Suppressive Cd8 Cells awarded by National Institutes of Health 1990 - 2000
- Anti-Hiv Ctl And Hiv-Suppresive Cd8+ Cells awarded by National Institutes of Health 1996 - 1999
- Anti-Hiv Ctl And Hiv Suppresive Cd8+ Cells awarded by National Institutes of Health 1995 - 1999
- Antihiv Ctl And Hiv Suppressive Cd8 Cells awarded by National Institutes of Health 1990 - 1999
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External Relationships
- University of Cape Town
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Stieh, Daniel J., Dan H. Barouch, Christy Comeaux, Michal Sarnecki, Kathryn E. Stephenson, Stephen R. Walsh, Sheetal Sawant, et al. “Safety and Immunogenicity of Ad26-Vectored HIV Vaccine With Mosaic Immunogens and a Novel Mosaic Envelope Protein in HIV-Uninfected Adults: A Phase 1/2a Study.” J Infect Dis 227, no. 8 (April 18, 2023): 939–50. https://doi.org/10.1093/infdis/jiac445.Full Text Link to Item
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Wilson, Gregory J., Benigno Rodriguez, Shuying Sue Li, Mary Allen, Ian Frank, Erika Rudnicki, Meg Trahey, et al. “Cellular and humoral responses to an HIV DNA prime by electroporation boosted with recombinant vesicular stomatitis virus expressing HIV subtype C Env in a randomized controlled clinical trial.” Vaccine 41, no. 16 (April 17, 2023): 2696–2706. https://doi.org/10.1016/j.vaccine.2023.03.015.Full Text Link to Item
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Berrong, Mark, Guido Ferrari, Cassie Porth, Devin Davis, Thomas Denny, Sylvia Janetzki, and Wes Rountree. “Validation of the performance and suitability of a new class of FBS optimized for use in single-cell functional assays.” J Immunol Methods 515 (April 2023): 113452. https://doi.org/10.1016/j.jim.2023.113452.Full Text Link to Item
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Milligan, Emma C., Katherine Olstad, Caitlin A. Williams, Michael Mallory, Patricio Cano, Kaitlyn A. Cross, Jennifer E. Munt, et al. “Infant rhesus macaques immunized against SARS-CoV-2 are protected against heterologous virus challenge 1 year later.” Sci Transl Med 15, no. 685 (March 2023): eadd6383. https://doi.org/10.1126/scitranslmed.add6383.Full Text Link to Item
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Kuriakose Gift, Syna, Lindsay Wieczorek, Eric Sanders-Buell, Michelle Zemil, Sebastian Molnar, Gina Donofrio, Samantha Townsley, et al. “Evolution of Antibody Responses in HIV-1 CRF01_AE Acute Infection: Founder Envelope V1V2 Impacts the Timing and Magnitude of Autologous Neutralizing Antibodies.” J Virol 97, no. 2 (February 28, 2023): e0163522. https://doi.org/10.1128/jvi.01635-22.Full Text Link to Item
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Cohen, Kristen W., Andrew Fiore-Gartland, Stephen R. Walsh, Karina Yusim, Nicole Frahm, Marnie L. Elizaga, Janine Maenza, et al. “Trivalent mosaic or consensus HIV immunogens prime humoral and broader cellular immune responses in adults.” J Clin Invest 133, no. 4 (February 15, 2023). https://doi.org/10.1172/JCI163338.Full Text Link to Item
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Bissa, Massimiliano, Sohyoung Kim, Veronica Galli, Slim Fourati, Sarkis Sarkis, Anush Arakelyan, Isabela Silva de Castro, et al. “HIV vaccine candidate efficacy in female macaques mediated by cAMP-dependent efferocytosis and V2-specific ADCC.” Nat Commun 14, no. 1 (February 2, 2023): 575. https://doi.org/10.1038/s41467-023-36109-8.Full Text Link to Item
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Crowley, Andrew R., Simone I. Richardson, Marina Tuyishime, Madeleine Jennewein, Meredith J. Bailey, Jiwon Lee, Galit Alter, Guido Ferrari, Lynn Morris, and Margaret E. Ackerman. “Functional consequences of allotypic polymorphisms in human immunoglobulin G subclasses.” Immunogenetics 75, no. 1 (February 2023): 1–16. https://doi.org/10.1007/s00251-022-01272-7.Full Text Link to Item
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Scarneo, Scott A., Aaron P. Smith, Jacob Favret, Robert O’Connell, Joy Pickeral, Kelly W. Yang, Guido Ferrari, et al. “Expression of membrane Hsp90 is a molecular signature of T cell activation.” Sci Rep 12, no. 1 (October 27, 2022): 18091. https://doi.org/10.1038/s41598-022-22788-8.Full Text Link to Item
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Li, Dapeng, David R. Martinez, Alexandra Schäfer, Haiyan Chen, Maggie Barr, Laura L. Sutherland, Esther Lee, et al. “Breadth of SARS-CoV-2 neutralization and protection induced by a nanoparticle vaccine.” Nat Commun 13, no. 1 (October 23, 2022): 6309. https://doi.org/10.1038/s41467-022-33985-4.Full Text Open Access Copy Link to Item
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Pollara, Justin, Santosh Khanal, R Whitney Edwards, Bhavna Hora, Guido Ferrari, Barton F. Haynes, and Todd Bradley. “Single-cell analysis of immune cell transcriptome during HIV-1 infection and therapy.” Bmc Immunol 23, no. 1 (September 29, 2022): 48. https://doi.org/10.1186/s12865-022-00523-2.Full Text Link to Item
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Nordstrom, Jeffrey L., Guido Ferrari, and David M. Margolis. “Bispecific antibody-derived molecules to target persistent HIV infection.” J Virus Erad 8, no. 3 (September 2022): 100083. https://doi.org/10.1016/j.jve.2022.100083.Full Text Link to Item
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Garrett, Nigel, Asa Tapley, Jessica Andriesen, Ishen Seocharan, Leigh H. Fisher, Lisa Bunts, Nicole Espy, et al. “High Asymptomatic Carriage With the Omicron Variant in South Africa.” Clin Infect Dis 75, no. 1 (August 24, 2022): e289–92. https://doi.org/10.1093/cid/ciac237.Full Text Link to Item
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Xu, Shiwei, Margaret C. Carpenter, Rachel L. Spreng, Scott D. Neidich, Sharanya Sarkar, DeAnna Tenney, Derrick Goodman, et al. “Impact of adjuvants on the biophysical and functional characteristics of HIV vaccine-elicited antibodies in humans.” Npj Vaccines 7, no. 1 (August 4, 2022): 90. https://doi.org/10.1038/s41541-022-00514-9.Full Text Link to Item
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Mielke, Dieter, Sherry Stanfield-Oakley, Shalini Jha, Taylor Keyes, Adam Zalaquett, Brooke Dunn, Nicole Rodgers, et al. “Development of flow cytometry-based assays to assess the ability of antibodies to bind to SARS-CoV-2-infected and spike-transfected cells and mediate NK cell degranulation.” Cytometry A 101, no. 6 (June 2022): 483–96. https://doi.org/10.1002/cyto.a.24552.Full Text Link to Item
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Gray, Matthew D., Junli Feng, Connor E. Weidle, Kristen W. Cohen, Lamar Ballweber-Fleming, Anna J. MacCamy, Crystal N. Huynh, et al. “Characterization of a vaccine-elicited human antibody with sequence homology to VRC01-class antibodies that binds the C1C2 gp120 domain.” Sci Adv 8, no. 18 (May 6, 2022): eabm3948. https://doi.org/10.1126/sciadv.abm3948.Full Text Link to Item
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DeGrace, Marciela M., Elodie Ghedin, Matthew B. Frieman, Florian Krammer, Alba Grifoni, Arghavan Alisoltani, Galit Alter, et al. “Defining the risk of SARS-CoV-2 variants on immune protection.” Nature 605, no. 7911 (May 2022): 640–52. https://doi.org/10.1038/s41586-022-04690-5.Full Text Link to Item
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Li, Dapeng, Simon Brackenridge, Lucy C. Walters, Olivia Swanson, Karl Harlos, Daniel Rozbesky, Derek W. Cain, et al. “Mouse and human antibodies bind HLA-E-leader peptide complexes and enhance NK cell cytotoxicity.” Commun Biol 5, no. 1 (March 28, 2022): 271. https://doi.org/10.1038/s42003-022-03183-5.Full Text Link to Item
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Gay, Cynthia L., Katherine S. James, Marina Tuyishime, Shane D. Falcinelli, Sarah B. Joseph, Matthew J. Moeser, Brigitte Allard, et al. “Stable Latent HIV Infection and Low-level Viremia Despite Treatment With the Broadly Neutralizing Antibody VRC07-523LS and the Latency Reversal Agent Vorinostat.” J Infect Dis 225, no. 5 (March 2, 2022): 856–61. https://doi.org/10.1093/infdis/jiab487.Full Text Link to Item
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Curtis, Alan D., Pooja T. Saha, Maria Dennis, Stella J. Berendam, Pratamesh Ramasubramanian, Kaitlyn A. Cross, S Munir Alam, et al. “Vaccine-Induced, High-Magnitude HIV Env-Specific Antibodies with Fc-Mediated Effector Functions Are Insufficient to Protect Infant Rhesus Macaques against Oral SHIV Infection.” Msphere 7, no. 1 (February 23, 2022): e0083921. https://doi.org/10.1128/msphere.00839-21.Full Text Link to Item
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Wang, Shixia, Nicole L. Yates, Justin Pollara, Yegor Voronin, Sherry Stanfield-Oakley, Dong Han, Guangnan Hu, et al. “Broadly binding and functional antibodies and persisting memory B cells elicited by HIV vaccine PDPHV.” Npj Vaccines 7, no. 1 (February 9, 2022): 18. https://doi.org/10.1038/s41541-022-00441-9.Full Text Link to Item
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Mielke, Dieter, Sherry Stanfield-Oakley, Bhavesh Borate, Leigh H. Fisher, Katelyn Faircloth, Marina Tuyishime, Kelli Greene, et al. “Selection of HIV Envelope Strains for Standardized Assessments of Vaccine-Elicited Antibody-Dependent Cellular Cytotoxicity-Mediating Antibodies.” J Virol 96, no. 2 (January 26, 2022): e0164321. https://doi.org/10.1128/JVI.01643-21.Full Text Link to Item
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Mitchell, Julie L., Justin Pollara, Kenneth Dietze, R Whitney Edwards, Junsuke Nohara, Kombo F. N’guessan, Michelle Zemil, et al. “Anti-HIV antibody development up to 1 year after antiretroviral therapy initiation in acute HIV infection.” J Clin Invest 132, no. 1 (January 4, 2022). https://doi.org/10.1172/JCI150937.Full Text Link to Item
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Barrows, Brittani M., Shelly J. Krebs, Ningbo Jian, Michelle Zemil, Bonnie M. Slike, Vincent Dussupt, Ursula Tran, et al. “Fc receptor engagement of HIV-1 Env-specific antibodies in mothers and infants predicts reduced vertical transmission.” Front Immunol 13 (2022): 1051501. https://doi.org/10.3389/fimmu.2022.1051501.Full Text Link to Item
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Lakhashe, Samir K., Mario Amacker, Dinesh Hariraju, Hemant K. Vyas, Kyle S. Morrison, Joshua A. Weiner, Margaret E. Ackerman, et al. “Cooperation Between Systemic and Mucosal Antibodies Induced by Virosomal Vaccines Targeting HIV-1 Env: Protection of Indian Rhesus Macaques Against Low-Dose Intravaginal SHIV Challenges.” Front Immunol 13 (2022): 788619. https://doi.org/10.3389/fimmu.2022.788619.Full Text Link to Item
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Perdiguero, Beatriz, Benedikt Asbach, Carmen E. Gómez, Josef Köstler, Susan W. Barnett, Marguerite Koutsoukos, Deborah E. Weiss, et al. “Early and Long-Term HIV-1 Immunogenicity Induced in Macaques by the Combined Administration of DNA, NYVAC and Env Protein-Based Vaccine Candidates: The AUP512 Study.” Front Immunol 13 (2022): 939627. https://doi.org/10.3389/fimmu.2022.939627.Full Text Link to Item
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Saunders, Kevin O., Norbert Pardi, Robert Parks, Sampa Santra, Zekun Mu, Laura Sutherland, Richard Scearce, et al. “Author Correction: Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.” Npj Vaccines 6, no. 1 (November 6, 2021): 136. https://doi.org/10.1038/s41541-021-00397-2.Full Text Link to Item
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Mielke, Dieter, Gama Bandawe, Jie Zheng, Jennifer Jones, Melissa-Rose Abrahams, Valerie Bekker, Christina Ochsenbauer, et al. “ADCC-mediating non-neutralizing antibodies can exert immune pressure in early HIV-1 infection.” Plos Pathog 17, no. 11 (November 2021): e1010046. https://doi.org/10.1371/journal.ppat.1010046.Full Text Link to Item
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Cheng, Hao D., Karen G. Dowell, Chris Bailey-Kellogg, Brittany A. Goods, J Christopher Love, Guido Ferrari, Galit Alter, et al. “Diverse antiviral IgG effector activities are predicted by unique biophysical antibody features.” Retrovirology 18, no. 1 (October 30, 2021): 35. https://doi.org/10.1186/s12977-021-00579-9.Full Text Link to Item
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Sherburn, Rebekah, William D. Tolbert, Suneetha Gottumukkala, Andrew P. Hederman, Guillaume Beaudoin-Bussières, Sherry Stanfield-Oakley, Marina Tuyishime, et al. “Incorporating the Cluster A and V1V2 Targets into a Minimal Structural Unit of the HIV-1 Envelope to Elicit a Cross-Clade Response with Potent Fc-Effector Functions.” Vaccines (Basel) 9, no. 9 (August 31, 2021). https://doi.org/10.3390/vaccines9090975.Full Text Link to Item
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Pino, Maria, Talha Abid, Susan Pereira Ribeiro, Venkata Viswanadh Edara, Katharine Floyd, Justin C. Smith, Muhammad Bilal Latif, et al. “A yeast expressed RBD-based SARS-CoV-2 vaccine formulated with 3M-052-alum adjuvant promotes protective efficacy in non-human primates.” Sci Immunol 6, no. 61 (July 15, 2021). https://doi.org/10.1126/sciimmunol.abh3634.Full Text Link to Item
-
Chua, Joel V., Charles Davis, Jennifer S. Husson, Amy Nelson, Ilia Prado, Robin Flinko, Ka Wing J. Lam, et al. “Safety and immunogenicity of an HIV-1 gp120-CD4 chimeric subunit vaccine in a phase 1a randomized controlled trial.” Vaccine 39, no. 29 (June 29, 2021): 3879–91. https://doi.org/10.1016/j.vaccine.2021.05.090.Full Text Link to Item
-
Saunders, Kevin O., Norbert Pardi, Robert Parks, Sampa Santra, Zekun Mu, Laura Sutherland, Richard Scearce, et al. “Lipid nanoparticle encapsulated nucleoside-modified mRNA vaccines elicit polyfunctional HIV-1 antibodies comparable to proteins in nonhuman primates.” Npj Vaccines 6, no. 1 (April 9, 2021): 50. https://doi.org/10.1038/s41541-021-00307-6.Full Text Link to Item
-
Tolbert, William D., Verna Van, Rebekah Sherburn, Marina Tuyishime, Fang Yan, Dung N. Nguyen, Sherry Stanfield-Oakley, et al. “Erratum for Tolbert et al., "Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial".” Mbio 12, no. 2 (April 6, 2021). https://doi.org/10.1128/mBio.00474-21.Full Text Link to Item
-
Andersen-Nissen, Erica, Andrew Fiore-Gartland, Lamar Ballweber Fleming, Lindsay N. Carpp, Anneta F. Naidoo, Michael S. Harper, Valentin Voillet, et al. “Innate immune signatures to a partially-efficacious HIV vaccine predict correlates of HIV-1 infection risk.” Plos Pathog 17, no. 3 (March 2021): e1009363. https://doi.org/10.1371/journal.ppat.1009363.Full Text Link to Item
-
Silva de Castro, Isabela, Giacomo Gorini, Rosemarie Mason, Jason Gorman, Massimiliano Bissa, Mohammad A. Rahman, Anush Arakelyan, et al. “Anti-V2 antibodies virus vulnerability revealed by envelope V1 deletion in HIV vaccine candidates.” Iscience 24, no. 2 (February 19, 2021): 102047. https://doi.org/10.1016/j.isci.2021.102047.Full Text Link to Item
-
Chattopadhyay, Pratip K., Andrew Filby, Evan R. Jellison, Guido Ferrari, Cherie Green, Sindhu Cherian, Jonathan Irish, Virginia Litwin, and Virginia other members of the ISAC COVID-19 Work Group. “A Cytometrist's Guide to Coordinating and Performing Effective COVID-19 Research.” Cytometry A 99, no. 1 (January 2021): 11–18. https://doi.org/10.1002/cyto.a.24210.Full Text Link to Item
-
Pollara, Justin, Matthew Zirui Tay, R Whitney Edwards, Derrick Goodman, Andrew R. Crowley, Robert J. Edwards, David Easterhoff, et al. “Functional Homology for Antibody-Dependent Phagocytosis Across Humans and Rhesus Macaques.” Frontiers in Immunology 12 (January 2021): 678511. https://doi.org/10.3389/fimmu.2021.678511.Full Text
-
Tolbert, William D., Dung N. Nguyen, Marina Tuyishime, Andrew R. Crowley, Yaozong Chen, Shalini Jha, Derrick Goodman, et al. “Structure and Fc-Effector Function of Rhesusized Variants of Human Anti-HIV-1 IgG1s.” Front Immunol 12 (2021): 787603. https://doi.org/10.3389/fimmu.2021.787603.Full Text Link to Item
-
Tuyishime, Marina, Amir Dashti, Katelyn Faircloth, Shalini Jha, Jeffrey L. Nordstrom, Barton F. Haynes, Guido Silvestri, Ann Chahroudi, David M. Margolis, and Guido Ferrari. “Elimination of SHIV Infected Cells by Combinations of Bispecific HIVxCD3 DART® Molecules.” Front Immunol 12 (2021): 710273. https://doi.org/10.3389/fimmu.2021.710273.Full Text Link to Item
-
White, Scott, John Quinn, Jennifer Enzor, Janet Staats, Sarah M. Mosier, James Almarode, Thomas N. Denny, Kent J. Weinhold, Guido Ferrari, and Cliburn Chan. “FlowKit: A Python Toolkit for Integrated Manual and Automated Cytometry Analysis Workflows.” Front Immunol 12 (2021): 768541. https://doi.org/10.3389/fimmu.2021.768541.Full Text Open Access Copy Link to Item
-
Devasundaram, Santhi, Margherita Rosati, Antonio Valentin, Svenja Weiss, Vincenza Itri, Hung V. Trinh, Jenifer Bear, et al. “Priming with DNA Expressing Trimeric HIV V1V2 Alters the Immune Hierarchy Favoring the Development of V2-Specific Antibodies in Rhesus Macaques.” J Virol 95, no. 2 (December 22, 2020). https://doi.org/10.1128/JVI.01193-20.Full Text Link to Item
-
Gay, Cynthia L., Dayna T. Neo, Aaron S. Devanathan, Joann D. Kuruc, Kara S. McGee, John L. Schmitz, Joe Sebastian, et al. “Efficacy, pharmacokinetics and neurocognitive performance of dual, NRTI-sparing antiretroviral therapy in acute HIV-infection.” Aids 34, no. 13 (November 1, 2020): 1923–31. https://doi.org/10.1097/QAD.0000000000002652.Full Text Link to Item
-
Baden, Lindsey R., Daniel J. Stieh, Michal Sarnecki, Stephen R. Walsh, Georgia D. Tomaras, James G. Kublin, M Juliana McElrath, et al. “Safety and immunogenicity of two heterologous HIV vaccine regimens in healthy, HIV-uninfected adults (TRAVERSE): a randomised, parallel-group, placebo-controlled, double-blind, phase 1/2a study.” Lancet Hiv 7, no. 10 (October 2020): e688–98. https://doi.org/10.1016/S2352-3018(20)30229-0.Full Text Link to Item
-
Tuyishime, Marina, Carolina Garrido, Shalini Jha, Matt Moeser, Dieter Mielke, Celia LaBranche, David Montefiori, et al. “Improved killing of HIV-infected cells using three neutralizing and non-neutralizing antibodies.” J Clin Invest 130, no. 10 (October 1, 2020): 5157–70. https://doi.org/10.1172/JCI135557.Full Text Link to Item
-
Om, Kier, Dominic Paquin-Proulx, Maria Montero, Kristina Peachman, Xiaoying Shen, Lindsay Wieczorek, Zoltan Beck, et al. “Adjuvanted HIV-1 vaccine promotes antibody-dependent phagocytic responses and protects against heterologous SHIV challenge.” Plos Pathog 16, no. 9 (September 2020): e1008764. https://doi.org/10.1371/journal.ppat.1008764.Full Text Link to Item
-
Tuyishime, Marina, and Guido Ferrari. “Engineering antibody-based molecules for HIV treatment and cure.” Curr Opin Hiv Aids 15, no. 5 (September 2020): 290–99. https://doi.org/10.1097/COH.0000000000000640.Full Text Link to Item
-
De Rosa, Stephen C., Srilatha Edupuganti, Yunda Huang, Xue Han, Marnie Elizaga, Edith Swann, Laura Polakowski, et al. “Robust antibody and cellular responses induced by DNA-only vaccination for HIV.” Jci Insight 5, no. 13 (July 9, 2020). https://doi.org/10.1172/jci.insight.137079.Full Text Link to Item
-
Tolbert, William D., Verna Van, Rebekah Sherburn, Marina Tuyishime, Fang Yan, Dung N. Nguyen, Sherry Stanfield-Oakley, et al. “Recognition Patterns of the C1/C2 Epitopes Involved in Fc-Mediated Response in HIV-1 Natural Infection and the RV114 Vaccine Trial.” Mbio 11, no. 3 (June 30, 2020). https://doi.org/10.1128/mBio.00208-20.Full Text Link to Item
-
Kasturi, Sudhir Pai, Mohammed Ata Ur Rasheed, Colin Havenar-Daughton, Mathew Pham, Traci Legere, Zarpheen Jinnah Sher, Yevgeny Kovalenkov, et al. “3M-052, a synthetic TLR-7/8 agonist, induces durable HIV-1 envelope-specific plasma cells and humoral immunity in nonhuman primates.” Sci Immunol 5, no. 48 (June 19, 2020). https://doi.org/10.1126/sciimmunol.abb1025.Full Text Link to Item
-
Lewis, Phoebe E., Ethan C. Poteet, Dongliang Liu, Changyi Chen, Celia C. LaBranche, Sherry A. Stanfield-Oakley, David C. Montefiori, Guido Ferrari, and Qizhi Yao. “CTLA-4 Blockade, during HIV Virus-Like Particles Immunization, Alters HIV-Specific B-Cell Responses.” Vaccines (Basel) 8, no. 2 (June 6, 2020). https://doi.org/10.3390/vaccines8020284.Full Text Link to Item
-
Garrido, Carolina, Maria Abad-Fernandez, Marina Tuyishime, Justin J. Pollara, Guido Ferrari, Natalia Soriano-Sarabia, and David M. Margolis. “Correction for Garrido et al., "Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo".” J Virol 94, no. 11 (May 18, 2020). https://doi.org/10.1128/JVI.00223-20.Full Text Link to Item
-
Felber, Barbara K., Zhongyan Lu, Xintao Hu, Antonio Valentin, Margherita Rosati, Christopher A. L. Remmel, Joshua A. Weiner, et al. “Co-immunization of DNA and Protein in the Same Anatomical Sites Induces Superior Protective Immune Responses against SHIV Challenge.” Cell Rep 31, no. 6 (May 12, 2020): 107624. https://doi.org/10.1016/j.celrep.2020.107624.Full Text Link to Item
-
Margolis, David M., Nancie M. Archin, Myron S. Cohen, Joseph J. Eron, Guido Ferrari, J Victor Garcia, Cynthia L. Gay, et al. “Curing HIV: Seeking to Target and Clear Persistent Infection.” Cell 181, no. 1 (April 2, 2020): 189–206. https://doi.org/10.1016/j.cell.2020.03.005.Full Text Link to Item
-
Curtis, Alan D., Maria Dennis, Joshua Eudailey, Korey L. Walter, Kenneth Cronin, S Munir Alam, Neelima Choudhary, et al. “HIV Env-Specific IgG Antibodies Induced by Vaccination of Neonatal Rhesus Macaques Persist and Can Be Augmented by a Late Booster Immunization in Infancy.” Msphere 5, no. 2 (March 25, 2020). https://doi.org/10.1128/mSphere.00162-20.Full Text Link to Item
-
Han, Qifeng, Todd Bradley, Wilton B. Williams, Derek W. Cain, David C. Montefiori, Kevin O. Saunders, Robert J. Parks, et al. “Neonatal Rhesus Macaques Have Distinct Immune Cell Transcriptional Profiles following HIV Envelope Immunization.” Cell Rep 30, no. 5 (February 4, 2020): 1553-1569.e6. https://doi.org/10.1016/j.celrep.2019.12.091.Full Text Open Access Copy Link to Item
-
Wise, Megan C., Ziyang Xu, Edgar Tello-Ruiz, Charles Beck, Aspen Trautz, Ami Patel, Sarah Tc Elliott, et al. “In vivo delivery of synthetic DNA-encoded antibodies induces broad HIV-1-neutralizing activity.” J Clin Invest 130, no. 2 (February 3, 2020): 827–37. https://doi.org/10.1172/JCI132779.Full Text Link to Item
-
Chu, Thach H., Andrew R. Crowley, Iara Backes, Cheryl Chang, Matthew Tay, Thomas Broge, Marina Tuyishime, et al. “Hinge length contributes to the phagocytic activity of HIV-specific IgG1 and IgG3 antibodies.” Plos Pathog 16, no. 2 (February 2020): e1008083. https://doi.org/10.1371/journal.ppat.1008083.Full Text Link to Item
-
Easterhoff, David, Justin Pollara, Kan Luo, William D. Tolbert, Brianna Young, Dieter Mielke, Shalini Jha, et al. “Boosting with AIDSVAX B/E Enhances Env Constant Region 1 and 2 Antibody-Dependent Cellular Cytotoxicity Breadth and Potency.” J Virol 94, no. 4 (January 31, 2020). https://doi.org/10.1128/JVI.01120-19.Full Text Link to Item
-
Easterhoff, David, Justin Pollara, Kan Luo, Benjamin Janus, Neelakshi Gohain, LaTonya D. Williams, Matthew Zirui Tay, et al. “HIV vaccine delayed boosting increases Env variable region 2-specific antibody effector functions.” Jci Insight 5, no. 2 (January 30, 2020). https://doi.org/10.1172/jci.insight.131437.Full Text Link to Item
-
Pollara, Justin, R Whitney Edwards, Shalini Jha, Chia-Ying Kao Lam, Liqin Liu, Gundo Diedrich, Jeffrey L. Nordstrom, et al. “Redirection of Cord Blood T Cells and Natural Killer Cells for Elimination of Autologous HIV-1-Infected Target Cells Using Bispecific DART® Molecules.” Front Immunol 11 (2020): 713. https://doi.org/10.3389/fimmu.2020.00713.Full Text Open Access Copy Link to Item
-
Giel-Moloney, M., M. Esteban, B. H. Oakes, M. Vaine, B. Asbach, R. Wagner, G. J. Mize, et al. “Recombinant HIV-1 vaccine candidates based on replication-defective flavivirus vector.” Sci Rep 9, no. 1 (December 27, 2019): 20005. https://doi.org/10.1038/s41598-019-56550-4.Full Text Link to Item
-
Kibler, Karen V., Benedikt Asbach, Beatriz Perdiguero, Juan García-Arriaza, Nicole L. Yates, Robert Parks, Sherry Stanfield-Oakley, et al. “Correction for Kibler et al., "Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC".” J Virol 93, no. 21 (November 1, 2019). https://doi.org/10.1128/JVI.00968-19.Full Text Link to Item
-
Li, Shuying S., Peter B. Gilbert, Lindsay N. Carpp, Chul-Woo Pyo, Holly Janes, Youyi Fong, Xiaoying Shen, et al. “Fc Gamma Receptor Polymorphisms Modulated the Vaccine Effect on HIV-1 Risk in the HVTN 505 HIV Vaccine Trial.” J Virol 93, no. 21 (November 1, 2019). https://doi.org/10.1128/JVI.02041-18.Full Text Link to Item
-
Neidich, Scott D., Youyi Fong, Shuying S. Li, Daniel E. Geraghty, Brian D. Williamson, William Chad Young, Derrick Goodman, et al. “Antibody Fc effector functions and IgG3 associate with decreased HIV-1 risk.” J Clin Invest 129, no. 11 (November 1, 2019): 4838–49. https://doi.org/10.1172/JCI126391.Full Text Link to Item
-
Pantaleo, Giuseppe, Holly Janes, Shelly Karuna, Shannon Grant, G Laissa Ouedraogo, Mary Allen, Georgia D. Tomaras, et al. “Safety and immunogenicity of a multivalent HIV vaccine comprising envelope protein with either DNA or NYVAC vectors (HVTN 096): a phase 1b, double-blind, placebo-controlled trial.” Lancet Hiv 6, no. 11 (November 2019): e737–49. https://doi.org/10.1016/S2352-3018(19)30262-0.Full Text Link to Item
-
Rouphael, Nadine G., Cecilia Morgan, Shuying S. Li, Ryan Jensen, Brittany Sanchez, Shelly Karuna, Edith Swann, et al. “DNA priming and gp120 boosting induces HIV-specific antibodies in a randomized clinical trial.” J Clin Invest 129, no. 11 (November 1, 2019): 4769–85. https://doi.org/10.1172/JCI128699.Full Text Link to Item
-
Gray, Glenda E., Ying Huang, Nicole Grunenberg, Fatima Laher, Surita Roux, Erica Andersen-Nissen, Stephen C. De Rosa, et al. “Immune correlates of the Thai RV144 HIV vaccine regimen in South Africa.” Sci Transl Med 11, no. 510 (September 18, 2019). https://doi.org/10.1126/scitranslmed.aax1880.Full Text Link to Item
-
Nyanhete, Tinashe E., Alyse L. Frisbee, Todd Bradley, William J. Faison, Elizabeth Robins, Tamika Payne, Stephanie A. Freel, et al. “HLA class II-Restricted CD8+ T cells in HIV-1 Virus Controllers.” Sci Rep 9, no. 1 (July 15, 2019): 10165. https://doi.org/10.1038/s41598-019-46462-8.Full Text Open Access Copy Link to Item
-
Pollara, Justin, Dorothy I. Jones, Tori Huffman, R Whitney Edwards, Maria Dennis, Shuk Hang Li, Shalini Jha, et al. “Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models.” J Virol 93, no. 10 (May 15, 2019). https://doi.org/10.1128/JVI.02119-18.Full Text Link to Item
-
Spearman, Paul, Georgia D. Tomaras, David C. Montefiori, Ying Huang, Marnie L. Elizaga, Guido Ferrari, S Munir Alam, et al. “Rapid Boosting of HIV-1 Neutralizing Antibody Responses in Humans Following a Prolonged Immunologic Rest Period.” J Infect Dis 219, no. 11 (May 5, 2019): 1755–65. https://doi.org/10.1093/infdis/jiz008.Full Text Link to Item
-
Pittala, Srivamshi, Kenneth Bagley, Jennifer A. Schwartz, Eric P. Brown, Joshua A. Weiner, Ilia J. Prado, Wenlei Zhang, et al. “Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection.” Mol Syst Biol 15, no. 5 (May 2, 2019): e8747. https://doi.org/10.15252/msb.20188747.Full Text Link to Item
-
Pardi, Norbert, Celia C. LaBranche, Guido Ferrari, Derek W. Cain, István Tombácz, Robert J. Parks, Hiromi Muramatsu, et al. “Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques.” Mol Ther Nucleic Acids 15 (April 15, 2019): 36–47. https://doi.org/10.1016/j.omtn.2019.03.003.Full Text Link to Item
-
Curtis, Alan D., Korey A. Walter, Rafiq Nabi, Kara Jensen, Aanini Dwivedi, Justin Pollara, Guido Ferrari, et al. “Oral Coadministration of an Intramuscular DNA/Modified Vaccinia Ankara Vaccine for Simian Immunodeficiency Virus Is Associated with Better Control of Infection in Orally Exposed Infant Macaques.” Aids Res Hum Retroviruses 35, no. 3 (March 2019): 310–25. https://doi.org/10.1089/AID.2018.0180.Full Text Link to Item
-
Dennis, Maria, Joshua Eudailey, Justin Pollara, Arthur S. McMillan, Kenneth D. Cronin, Pooja T. Saha, Alan D. Curtis, et al. “Coadministration of CH31 Broadly Neutralizing Antibody Does Not Affect Development of Vaccine-Induced Anti-HIV-1 Envelope Antibody Responses in Infant Rhesus Macaques.” J Virol 93, no. 5 (March 1, 2019). https://doi.org/10.1128/JVI.01783-18.Full Text Link to Item
-
Kibler, Karen V., Benedikt Asbach, Beatriz Perdiguero, Juan García-Arriaza, Nicole L. Yates, Robert Parks, Sherry Stanfield-Oakley, et al. “Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC.” J Virol 93, no. 3 (February 1, 2019). https://doi.org/10.1128/JVI.01513-18.Full Text Link to Item
-
Pantaleo, Giuseppe, Holly Janes, Shelly Karuna, Shannon Grant, Laissa Ouedraogo, Mary Allen, Georgia D. Tomaras, et al. “Co-Administration of HIV Env Protein with DNA and/or NYVAC Vaccines in Humans Results in Earlier and Potent Generation of Anti-Env Antibody Responses.” The Lancet Hiv, Volume 6, no. 11 (January 25, 2019).
-
Mielke, Dieter, Gama Bandawe, Justin Pollara, Melissa-Rose Abrahams, Tinashe Nyanhete, Penny L. Moore, Ruwayhida Thebus, et al. “Antibody-Dependent Cellular Cytotoxicity (ADCC)-Mediating Antibodies Constrain Neutralizing Antibody Escape Pathway.” Front Immunol 10 (2019): 2875. https://doi.org/10.3389/fimmu.2019.02875.Full Text Link to Item
-
Fisher, Leigh, Melissa Zinter, Sherry Stanfield-Oakley, Lindsay N. Carpp, R Whitney Edwards, Thomas Denny, Zoe Moodie, et al. “Vaccine-Induced Antibodies Mediate Higher Antibody-Dependent Cellular Cytotoxicity After Interleukin-15 Pretreatment of Natural Killer Effector Cells.” Front Immunol 10 (2019): 2741. https://doi.org/10.3389/fimmu.2019.02741.Full Text Open Access Copy Link to Item
-
Lewis, George K., Margaret E. Ackerman, Gabriella Scarlatti, Christiane Moog, Marjorie Robert-Guroff, Stephen J. Kent, Julie Overbaugh, R Keith Reeves, Guido Ferrari, and Bargavi Thyagarajan. “Knowns and Unknowns of Assaying Antibody-Dependent Cell-Mediated Cytotoxicity Against HIV-1.” Front Immunol 10 (2019): 1025. https://doi.org/10.3389/fimmu.2019.01025.Full Text Link to Item
-
Manickam, Cordelia, Spandan V. Shah, Junsuke Nohara, Guido Ferrari, and R Keith Reeves. “Monkeying Around: Using Non-human Primate Models to Study NK Cell Biology in HIV Infections.” Front Immunol 10 (2019): 1124. https://doi.org/10.3389/fimmu.2019.01124.Full Text Link to Item
-
Eeden, Charmaine van, Constantinos Kurt Wibmer, Cathrine Scheepers, Simone I. Richardson, Molati Nonyane, Bronwen Lambson, Nonhlanhla N. Mkhize, et al. “V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity.” Cell Rep 25, no. 11 (December 11, 2018): 3123-3135.e6. https://doi.org/10.1016/j.celrep.2018.11.058.Full Text Link to Item
-
Himes, Jonathon E., Ria Goswami, Riley J. Mangan, Amit Kumar, Thomas L. Jeffries, Joshua A. Eudailey, Holly Heimsath, et al. “Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys.” Mucosal Immunol 11, no. 6 (November 2018): 1716–26. https://doi.org/10.1038/s41385-018-0067-7.Full Text Link to Item
-
Phillips, Bonnie, Koen K. A. Van Rompay, Jennifer Rodriguez-Nieves, Clarisse Lorin, Marguerite Koutsoukos, Mark Tomai, Christopher B. Fox, et al. “Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques.” J Virol 92, no. 20 (October 15, 2018). https://doi.org/10.1128/JVI.01051-18.Full Text Link to Item
-
Bradley, Todd, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao, Vaishnavi Venkat, et al. “RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses.” Cell 175, no. 2 (October 4, 2018): 387-399.e17. https://doi.org/10.1016/j.cell.2018.08.064.Full Text Link to Item
-
Bradley, Todd, Guido Ferrari, Barton F. Haynes, David M. Margolis, and Edward P. Browne. “Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency.” Cell Rep 25, no. 1 (October 2, 2018): 107-117.e3. https://doi.org/10.1016/j.celrep.2018.09.020.Full Text Link to Item
-
Singh, Shakti, Eric G. Ramírez-Salazar, Rami Doueiri, Antonio Valentin, Margherita Rosati, Xintao Hu, Brandon F. Keele, et al. “Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques.” J Virol 92, no. 15 (August 1, 2018). https://doi.org/10.1128/JVI.00281-18.Full Text Link to Item
-
Naggie, Susanna, Marzena Swiderska-Syn, Steve Choi, Sam Lusk, Audrey Lan, Guido Ferrari, Wing-Kin Syn, Cynthia D. Guy, and Anna Mae Diehl. “Markers of Tissue Repair and Cellular Aging Are Increased in the Liver Tissue of Patients With HIV Infection Regardless of Presence of HCV Coinfection.” Open Forum Infect Dis 5, no. 7 (July 2018): ofy138. https://doi.org/10.1093/ofid/ofy138.Full Text Open Access Copy Link to Item
-
Garrido, Carolina, Maria Abad-Fernandez, Marina Tuyishime, Justin J. Pollara, Guido Ferrari, Natalia Soriano-Sarabia, and David M. Margolis. “Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo.” J Virol 92, no. 12 (June 15, 2018). https://doi.org/10.1128/JVI.00235-18.Full Text Link to Item
-
Ferrari, Guido. “Tandem bispecific broadly neutralizing antibody - a novel approach to HIV-1 treatment.” J Clin Invest 128, no. 6 (June 1, 2018): 2189–91. https://doi.org/10.1172/JCI121078.Full Text Link to Item
-
Saunders, Kevin O., Sampa Santra, Robert Parks, Nicole L. Yates, Laura L. Sutherland, Richard M. Scearce, Harikrishnan Balachandran, et al. “Immunogenicity of NYVAC Prime-Protein Boost Human Immunodeficiency Virus Type 1 Envelope Vaccination and Simian-Human Immunodeficiency Virus Challenge of Nonhuman Primates.” J Virol 92, no. 8 (April 15, 2018). https://doi.org/10.1128/JVI.02035-17.Full Text Link to Item
-
Pollara, Justin, Chiara Orlandi, Charles Beck, R Whitney Edwards, Yi Hu, Shuying Liu, Shixia Wang, et al. “Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay.” Cytometry A 93, no. 4 (April 2018): 436–47. https://doi.org/10.1002/cyto.a.23348.Full Text Open Access Copy Link to Item
-
Wills, Saintedym, Kwan-Ki Hwang, Pinghuang Liu, S Moses Dennison, Matthew Zirui Tay, Xiaoying Shen, Justin Pollara, et al. “HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis.” J Virol 92, no. 7 (April 1, 2018). https://doi.org/10.1128/JVI.01552-17.Full Text Link to Item
-
Fong, Youyi, Xiaoying Shen, Vicki C. Ashley, Aaron Deal, Kelly E. Seaton, Chenchen Yu, Shannon P. Grant, et al. “Modification of the Association Between T-Cell Immune Responses and Human Immunodeficiency Virus Type 1 Infection Risk by Vaccine-Induced Antibody Responses in the HVTN 505 Trial.” J Infect Dis 217, no. 8 (March 28, 2018): 1280–88. https://doi.org/10.1093/infdis/jiy008.Full Text Link to Item
-
Francica, J. R., D. E. Zak, C. Linde, E. Siena, C. Johnson, M. Juraska, N. L. Yates, et al. “Erratum: Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs (Blood Advances (2017) 1:25 (2329-2342) DOI: 10.1182/bloodadvances.2017011411).” Blood Advances 2, no. 5 (March 13, 2018): 516. https://doi.org/10.1182/bloodadvances.2018017491.Full Text
-
Jones, Andrew T., Venkateswarlu Chamcha, Sannula Kesavardhana, Xiaoying Shen, David Beaumont, Raksha Das, Linda S. Wyatt, et al. “A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques.” J Virol 92, no. 5 (March 1, 2018). https://doi.org/10.1128/JVI.01796-17.Full Text Link to Item
-
Viegas, Edna Omar, Nelson Tembe, Charlotta Nilsson, Bindiya Meggi, Cremildo Maueia, Orvalho Augusto, Richard Stout, et al. “Intradermal HIV-1 DNA Immunization Using Needle-Free Zetajet Injection Followed by HIV-Modified Vaccinia Virus Ankara Vaccination Is Safe and Immunogenic in Mozambican Young Adults: A Phase I Randomized Controlled Trial.” Aids Res Hum Retroviruses 34, no. 2 (February 2018): 193–205. https://doi.org/10.1089/AID.2017.0121.Full Text Link to Item
-
Blasi, Maria, Donatella Negri, Celia LaBranche, S Munir Alam, Erich J. Baker, Elizabeth C. Brunner, Morgan A. Gladden, et al. “IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells.” Commun Biol 1 (2018): 134. https://doi.org/10.1038/s42003-018-0131-6.Full Text Open Access Copy Link to Item
-
Eudailey, Joshua A., Maria L. Dennis, Morgan E. Parker, Bonnie L. Phillips, Tori N. Huffman, Camden P. Bay, Michael G. Hudgens, et al. “Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques.” Msphere 3, no. 1 (2018). https://doi.org/10.1128/mSphere.00505-17.Full Text Open Access Copy Link to Item
-
Shen, Xiaoying, Rahul Basu, Sheetal Sawant, David Beaumont, Sue Fen Kwa, Celia LaBranche, Kelly E. Seaton, et al. “HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine.” J Virol 91, no. 24 (December 15, 2017). https://doi.org/10.1128/JVI.01077-17.Full Text Link to Item
-
Francica, Joseph R., Daniel E. Zak, Caitlyn Linde, Emilio Siena, Carrie Johnson, Michal Juraska, Nicole L. Yates, et al. “Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs.” Blood Adv 1, no. 25 (November 28, 2017): 2329–42. https://doi.org/10.1182/bloodadvances.2017011411.Full Text Link to Item
-
Mayer, Kenneth H., Kelly E. Seaton, Yunda Huang, Nicole Grunenberg, Abby Isaacs, Mary Allen, Julie E. Ledgerwood, et al. “Safety, pharmacokinetics, and immunological activities of multiple intravenous or subcutaneous doses of an anti-HIV monoclonal antibody, VRC01, administered to HIV-uninfected adults: Results of a phase 1 randomized trial.” Plos Med 14, no. 11 (November 2017): e1002435. https://doi.org/10.1371/journal.pmed.1002435.Full Text Link to Item
-
Liu, Donglai, Chu Wang, Bhavna Hora, Tao Zuo, Nilu Goonetilleke, Michael K. P. Liu, Mark Berrong, et al. “A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies.” Retrovirology 14, no. 1 (October 10, 2017): 46. https://doi.org/10.1186/s12977-017-0371-4.Full Text Link to Item
-
Bogers, Willy M. J. M., Susan W. Barnett, Herman Oostermeijer, Ivonne G. Nieuwenhuis, Niels Beenhakker, Daniella Mortier, Petra Mooij, et al. “Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site.” J Virol 91, no. 19 (October 1, 2017). https://doi.org/10.1128/JVI.00811-17.Full Text Link to Item
-
Phillips, Bonnie, Genevieve G. Fouda, Josh Eudailey, Justin Pollara, Alan D. Curtis, Erika Kunz, Maria Dennis, et al. “Impact of Poxvirus Vector Priming, Protein Coadministration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques.” Clin Vaccine Immunol 24, no. 10 (October 2017). https://doi.org/10.1128/CVI.00231-17.Full Text Link to Item
-
Shen, Xiaoying, Willy M. Bogers, Nicole L. Yates, Guido Ferrari, Antu K. Dey, William T. Williams, Frederick H. Jaeger, et al. “Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques.” J Virol 91, no. 19 (October 1, 2017). https://doi.org/10.1128/JVI.00401-17.Full Text Link to Item
-
Meyerhoff, R Ryan, Richard M. Scearce, Damon F. Ogburn, Brad Lockwood, Joy Pickeral, Masa Kuraoka, Kara Anasti, et al. “HIV-1 Consensus Envelope-Induced Broadly Binding Antibodies.” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 859–68. https://doi.org/10.1089/AID.2016.0294.Full Text Link to Item
-
Joachim, Agricola, Patricia J. Munseri, Charlotta Nilsson, Muhammad Bakari, Said Aboud, Eligius F. Lyamuya, Teghesti Tecleab, et al. “Three-Year Durability of Immune Responses Induced by HIV-DNA and HIV-Modified Vaccinia Virus Ankara and Effect of a Late HIV-Modified Vaccinia Virus Ankara Boost in Tanzanian Volunteers.” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 880–88. https://doi.org/10.1089/AID.2016.0251.Full Text Link to Item
-
Lewis, George K., Marzena Pazgier, David T. Evans, Guido Ferrari, Stylianos Bournazos, Matthew S. Parsons, Nicole F. Bernard, and Andrés Finzi. “Beyond Viral Neutralization.” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 760–64. https://doi.org/10.1089/AID.2016.0299.Full Text Link to Item
-
Bradley, Todd, Justin Pollara, Sampa Santra, Nathan Vandergrift, Srivamshi Pittala, Chris Bailey-Kellogg, Xiaoying Shen, et al. “Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge.” Nat Commun 8 (June 8, 2017): 15711. https://doi.org/10.1038/ncomms15711.Full Text Link to Item
-
Wang, Chu, Chunlai Jiang, Nan Gao, Kaikai Zhang, Donglai Liu, Wei Wang, Zhe Cong, et al. “Immunologic and Virologic Mechanisms for Partial Protection from Intravenous Challenge by an Integration-Defective SIV Vaccine.” Viruses 9, no. 6 (June 2, 2017). https://doi.org/10.3390/v9060135.Full Text Link to Item
-
Shubin, Zhanna, Weizhong Li, Bhawna Poonia, Guido Ferrari, Celia LaBranche, David Montefiori, Xiaoping Zhu, and C David Pauza. “An HIV Envelope gp120-Fc Fusion Protein Elicits Effector Antibody Responses in Rhesus Macaques.” Clin Vaccine Immunol 24, no. 6 (June 2017). https://doi.org/10.1128/CVI.00028-17.Full Text Link to Item
-
García-Arriaza, Juan, Beatriz Perdiguero, Jonathan L. Heeney, Michael S. Seaman, David C. Montefiori, Nicole L. Yates, Georgia D. Tomaras, et al. “HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Specific B and T Cell Immune Functions in Nonhuman Primates.” J Virol 91, no. 9 (May 1, 2017). https://doi.org/10.1128/JVI.02182-16.Full Text Link to Item
-
Zurawski, Gerard, Xiaoying Shen, Sandra Zurawski, Georgia D. Tomaras, David C. Montefiori, Mario Roederer, Guido Ferrari, et al. “Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses.” J Virol 91, no. 9 (May 1, 2017). https://doi.org/10.1128/JVI.01596-16.Full Text Link to Item
-
Ferrari, Guido, Justin Pollara, Georgia D. Tomaras, and Barton F. Haynes. “Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection.” J Infect Dis 215, no. suppl_3 (March 15, 2017): S152–59. https://doi.org/10.1093/infdis/jiw555.Full Text Link to Item
-
Chege, Gerald K., Wendy A. Burgers, Tracey L. Müller, Clive M. Gray, Enid G. Shephard, Susan W. Barnett, Guido Ferrari, David Montefiori, Carolyn Williamson, and Anna-Lise Williamson. “DNA-MVA-protein vaccination of rhesus macaques induces HIV-specific immunity in mucosal-associated lymph nodes and functional antibodies.” Vaccine 35, no. 6 (February 7, 2017): 929–37. https://doi.org/10.1016/j.vaccine.2016.12.060.Full Text Link to Item
-
Easterhoff, David, M Anthony Moody, Daniela Fera, Hao Cheng, Margaret Ackerman, Kevin Wiehe, Kevin O. Saunders, et al. “Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial.” Plos Pathog 13, no. 2 (February 2017): e1006182. https://doi.org/10.1371/journal.ppat.1006182.Full Text Link to Item
-
Ferrari, G. “Meet our editorial board member.” Current Hiv Research 15, no. 1 (January 1, 2017): 1. https://doi.org/10.2174/1570162X1501170120194811.Full Text
-
Hankins, Catherine A., Sinata Koulla-Shiro, Peter Kilmarx, Guido Ferrari, Mauro Schechter, Coumba Touré Kane, François Venter, et al. “Ending AIDS as a public health threat by 2030: Scientific Developments from the 2016 INTEREST Conference in Yaoundé, Cameroon.” Antivir Ther 22, no. 2 (2017): 179–84. https://doi.org/10.3851/IMP3165.Full Text Link to Item
-
Buchbinder, Susan P., Nicole A. Grunenberg, Brittany J. Sanchez, Kelly E. Seaton, Guido Ferrari, M Anthony Moody, Nicole Frahm, et al. “Immunogenicity of a novel Clade B HIV-1 vaccine combination: Results of phase 1 randomized placebo controlled trial of an HIV-1 GM-CSF-expressing DNA prime with a modified vaccinia Ankara vaccine boost in healthy HIV-1 uninfected adults.” Plos One 12, no. 7 (January 2017): e0179597. https://doi.org/10.1371/journal.pone.0179597.Full Text
-
Margolis, David M., Richard A. Koup, and Guido Ferrari. “HIV antibodies for treatment of HIV infection.” Immunol Rev 275, no. 1 (January 2017): 313–23. https://doi.org/10.1111/imr.12506.Full Text Link to Item
-
Huang, Yunda, Guido Ferrari, Galit Alter, Donald N. Forthal, John C. Kappes, George K. Lewis, J Christopher Love, et al. “Diversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects.” J Immunol 197, no. 12 (December 15, 2016): 4603–12. https://doi.org/10.4049/jimmunol.1601197.Full Text Link to Item
-
Luo, Kan, Hua-Xin Liao, Ruijun Zhang, David Easterhoff, Kevin Wiehe, Thaddeus C. Gurley, Lawrence C. Armand, et al. “Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques.” Jci Insight 1, no. 20 (December 8, 2016): e88522. https://doi.org/10.1172/jci.insight.88522.Full Text Link to Item
-
Ferrari, Guido, Barton F. Haynes, Scott Koenig, Jeffrey L. Nordstrom, David M. Margolis, and Georgia D. Tomaras. “Envelope-specific antibodies and antibody-derived molecules for treating and curing HIV infection.” Nat Rev Drug Discov 15, no. 12 (December 2016): 823–34. https://doi.org/10.1038/nrd.2016.173.Full Text Link to Item
-
Astronomo, Rena D., Sampa Santra, Lamar Ballweber-Fleming, Katharine G. Westerberg, Linh Mach, Tiffany Hensley-McBain, Laura Sutherland, et al. “Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection.” Ebiomedicine 14 (December 2016): 97–111. https://doi.org/10.1016/j.ebiom.2016.11.024.Full Text Open Access Copy Link to Item
-
Gay, Cynthia L., Sarah J. Willis, Anna B. Cope, JoAnn D. Kuruc, Kara S. McGee, Joe Sebastian, Amanda M. Crooks, et al. “Fixed-dose combination emtricitabine/tenofovir/efavirenz initiated during acute HIV infection; 96-week efficacy and durability.” Aids 30, no. 18 (November 28, 2016): 2815–22. https://doi.org/10.1097/QAD.0000000000001255.Full Text Link to Item
-
Altenburg, Arwen F., Carolien E. van de Sandt, Stella E. van Trierum, Heidi L. M. De Gruyter, Peter R. W. A. van Run, Ron A. M. Fouchier, Kenny Roose, et al. “Increased Protein Degradation Improves Influenza Virus Nucleoprotein-Specific CD8+ T Cell Activation In Vitro but Not in C57BL/6 Mice.” J Virol 90, no. 22 (November 15, 2016): 10209–19. https://doi.org/10.1128/JVI.01633-16.Full Text Link to Item
-
Costa, Matthew R., Justin Pollara, Regina Whitney Edwards, Michael S. Seaman, Miroslaw K. Gorny, David C. Montefiori, Hua-Xin Liao, Guido Ferrari, Shan Lu, and Shixia Wang. “Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001.” J Virol 90, no. 22 (November 15, 2016): 10362–78. https://doi.org/10.1128/JVI.01458-16.Full Text Link to Item
-
Negri, Donatella, Maria Blasi, Celia LaBranche, Robert Parks, Harikrishnan Balachandran, Michelle Lifton, Xiaoying Shen, et al. “Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques.” Mol Ther 24, no. 11 (November 2016): 2021–32. https://doi.org/10.1038/mt.2016.123.Full Text Open Access Copy Link to Item
-
Nemes, Elisa, Wendy A. Burgers, Catherine Riou, Erica Andersen-Nissen, Guido Ferrari, Clive M. Gray, and Thomas Scriba. “Teaching advanced flow cytometry in Africa: 10 years of lessons learned.” Cytometry A 89, no. 11 (November 2016): 971–74. https://doi.org/10.1002/cyto.a.23015.Full Text Link to Item
-
Vaccari, Monica, Shari N. Gordon, Slim Fourati, Luca Schifanella, Namal P. M. Liyanage, Mark Cameron, Brandon F. Keele, et al. “Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.” Nat Med 22, no. 10 (October 6, 2016): 1192. https://doi.org/10.1038/nm1016-1192a.Full Text Link to Item
-
Gordon, Shari N., Namal P. M. Liyanage, Melvin N. Doster, Monica Vaccari, Diego A. Vargas-Inchaustegui, Poonam Pegu, Luca Schifanella, et al. “Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIVmac251 Acquisition.” J Immunol 197, no. 7 (October 1, 2016): 2726–37. https://doi.org/10.4049/jimmunol.1600674.Full Text Link to Item
-
Townsley, Samantha, Zeinab Mohamed, Wenjin Guo, Jennifer McKenna, Brad Cleveland, Celia LaBranche, David Beaumont, et al. “Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization.” J Virol 90, no. 19 (October 1, 2016): 8644–60. https://doi.org/10.1128/JVI.00853-16.Full Text Link to Item
-
Zhang, Ruijun, David R. Martinez, Quang N. Nguyen, Justin Pollara, Trina Arifin, Christina Stolarchuk, Andrew Foulger, et al. “Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus.” Nat Commun 7 (July 6, 2016): 12131. https://doi.org/10.1038/ncomms12131.Full Text Link to Item
-
Vaccari, Monica, Shari N. Gordon, Slim Fourati, Luca Schifanella, Namal P. M. Liyanage, Mark Cameron, Brandon F. Keele, et al. “Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition.” Nat Med 22, no. 7 (July 2016): 762–70. https://doi.org/10.1038/nm.4105.Full Text Link to Item
-
Rountree, Wes, Mark Berrong, Ana M. Sanchez, Thomas N. Denny, and Guido Ferrari. “Variability of the IFN-γ ELISpot assay in the context of proficiency testing and bridging studies.” J Immunol Methods 433 (June 2016): 69–76. https://doi.org/10.1016/j.jim.2016.03.004.Full Text Open Access Copy Link to Item
-
Nelson, Cody S., Justin Pollara, Erika L. Kunz, Thomas L. Jeffries, Ryan Duffy, Charles Beck, Lisa Stamper, et al. “Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk.” J Virol 90, no. 10 (May 15, 2016): 4951–65. https://doi.org/10.1128/JVI.00335-16.Full Text Link to Item
-
Asbach, Benedikt, Alexander Kliche, Josef Köstler, Beatriz Perdiguero, Mariano Esteban, Bertram L. Jacobs, David C. Montefiori, et al. “Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens.” J Virol 90, no. 8 (April 2016): 4133–49. https://doi.org/10.1128/JVI.03135-15.Full Text Open Access Copy Link to Item
-
Jeffries, T. L., C. R. Sacha, J. Pollara, J. Himes, F. H. Jaeger, S. M. Dennison, E. McGuire, et al. “The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells.” Mucosal Immunol 9, no. 2 (March 2016): 414–27. https://doi.org/10.1038/mi.2015.70.Full Text Link to Item
-
Ding, Shilei, Maxime Veillette, Mathieu Coutu, Jérémie Prévost, Louise Scharf, Pamela J. Bjorkman, Guido Ferrari, et al. “A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies.” J Virol 90, no. 4 (February 15, 2016): 2127–34. https://doi.org/10.1128/JVI.02779-15.Full Text Link to Item
-
Zurawski, Gerard, Sandra Zurawski, Anne-Laure Flamar, Laura Richert, Ralf Wagner, Georgia D. Tomaras, David C. Montefiori, et al. “Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques.” Plos One 11, no. 4 (2016): e0153484. https://doi.org/10.1371/journal.pone.0153484.Full Text Link to Item
-
Cosgrove, Catherine A., Charles J. Lacey, Alethea V. Cope, Angela Bartolf, Georgina Morris, Celine Yan, Susan Baden, et al. “Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study.” Plos One 11, no. 5 (2016): e0152038. https://doi.org/10.1371/journal.pone.0152038.Full Text Link to Item
-
Joachim, Agricola, Asli Bauer, Sarah Joseph, Christof Geldmacher, Patricia J. Munseri, Said Aboud, Marco Missanga, et al. “Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Trial.” Plos One 11, no. 5 (2016): e0155702. https://doi.org/10.1371/journal.pone.0155702.Full Text Link to Item
-
Lai, Weihong, Li Huang, Lei Zhu, Guido Ferrari, Cliburn Chan, Wei Li, Kuo-Hsiung Lee, and Chin-Ho Chen. “Gnidimacrin, a Potent Anti-HIV Diterpene, Can Eliminate Latent HIV-1 Ex Vivo by Activation of Protein Kinase C β.” J Med Chem 58, no. 21 (November 12, 2015): 8638–46. https://doi.org/10.1021/acs.jmedchem.5b01233.Full Text Link to Item
-
Sung, Julia A. M., Joy Pickeral, Liqin Liu, Sherry A. Stanfield-Oakley, Chia-Ying Kao Lam, Carolina Garrido, Justin Pollara, et al. “Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells.” J Clin Invest 125, no. 11 (November 2, 2015): 4077–90. https://doi.org/10.1172/JCI82314.Full Text Link to Item
-
Pollara, Justin, Erin McGuire, Genevieve G. Fouda, Wes Rountree, Josh Eudailey, R Glenn Overman, Kelly E. Seaton, et al. “Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1.” J Virol 89, no. 19 (October 2015): 9952–61. https://doi.org/10.1128/JVI.01560-15.Full Text Open Access Copy Link to Item
-
Moody, M Anthony, Feng Gao, Thaddeus C. Gurley, Joshua D. Amos, Amit Kumar, Bhavna Hora, Dawn J. Marshall, et al. “Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses.” Cell Host Microbe 18, no. 3 (September 9, 2015): 354–62. https://doi.org/10.1016/j.chom.2015.08.006.Full Text Link to Item
-
Wise, Megan C., Natalie A. Hutnick, Justin Pollara, Devin J. F. Myles, Constance Williams, Jian Yan, Celia C. LaBranche, et al. “An Enhanced Synthetic Multiclade DNA Prime Induces Improved Cross-Clade-Reactive Functional Antibodies when Combined with an Adjuvanted Protein Boost in Nonhuman Primates.” J Virol 89, no. 18 (September 2015): 9154–66. https://doi.org/10.1128/JVI.00652-15.Full Text Link to Item
-
Williams, Wilton B., Hua-Xin Liao, M Anthony Moody, Thomas B. Kepler, S Munir Alam, Feng Gao, Kevin Wiehe, et al. “HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies.” Science 349, no. 6249 (August 14, 2015): aab1253. https://doi.org/10.1126/science.aab1253.Full Text Link to Item
-
García-Arriaza, Juan, Beatriz Perdiguero, Jonathan Heeney, Michael Seaman, David C. Montefiori, Celia Labranche, Nicole L. Yates, et al. “Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman Primates.” J Virol 89, no. 16 (August 2015): 8525–39. https://doi.org/10.1128/JVI.01265-15.Full Text Link to Item
-
Santra, Sampa, Georgia D. Tomaras, Ranjit Warrier, Nathan I. Nicely, Hua-Xin Liao, Justin Pollara, Pinghuang Liu, et al. “Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques.” Plos Pathog 11, no. 8 (August 2015): e1005042. https://doi.org/10.1371/journal.ppat.1005042.Full Text Open Access Copy Link to Item
-
Prentice, Heather A., Georgia D. Tomaras, Daniel E. Geraghty, Richard Apps, Youyi Fong, Philip K. Ehrenberg, Morgane Rolland, et al. “HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition.” Sci Transl Med 7, no. 296 (July 15, 2015): 296ra112. https://doi.org/10.1126/scitranslmed.aab4005.Full Text Link to Item
-
Permar, Sallie R., Youyi Fong, Nathan Vandergrift, Genevieve G. Fouda, Peter Gilbert, Robert Parks, Frederick H. Jaeger, et al. “Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission.” J Clin Invest 125, no. 7 (July 1, 2015): 2702–6. https://doi.org/10.1172/JCI81593.Full Text Open Access Copy Link to Item
-
Mimano, L. N., G. Ferrari, G. Kapanda, E. Lisasi, A. Kulanga, B. Nyombi, C. Muiruri, E. Kessi, J. Bartlett, and M. Ntabaye. “Student perceptions on the introduction of training in diagnostic laboratory techniques in an African school of medicine.” Mededpublish, April 1, 2015. https://doi.org/10.15694/mep.2015.005.0008.Full Text
-
Fouda, Genevieve G., Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Petronella Muresan, Justin Pollara, Lin Ye Song, et al. “Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses.” J Infect Dis 211, no. 4 (February 15, 2015): 508–17. https://doi.org/10.1093/infdis/jiu444.Full Text Link to Item
-
Hancock, Gemma, Hongbing Yang, Elisabeth Yorke, Emma Wainwright, Victoria Bourne, Alyse Frisbee, Tamika L. Payne, et al. “Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses.” Plos Pathog 11, no. 2 (February 2015): e1004658. https://doi.org/10.1371/journal.ppat.1004658.Full Text Link to Item
-
Joachim, Agricola, Charlotta Nilsson, Said Aboud, Muhammad Bakari, Eligius F. Lyamuya, Merlin L. Robb, Mary A. Marovich, et al. “Potent functional antibody responses elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults.” Plos One 10, no. 4 (2015): e0118486. https://doi.org/10.1371/journal.pone.0118486.Full Text Open Access Copy Link to Item
-
Gordon, Shari N., Melvin N. Doster, Rhonda C. Kines, Brandon F. Keele, Egidio Brocca-Cofano, Yongjun Guan, Poonam Pegu, et al. “Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia.” J Immunol 193, no. 12 (December 15, 2014): 6172–83. https://doi.org/10.4049/jimmunol.1401504.Full Text Link to Item
-
Stieh, Daniel J., Deborah F. King, Katja Klein, Pinghuang Liu, Xiaoying Shen, Kwan Ki Hwang, Guido Ferrari, et al. “Aggregate complexes of HIV-1 induced by multimeric antibodies.” Retrovirology 11, no. 1 (December 2014). https://doi.org/10.1186/s12977-014-0078-8.Full Text
-
Stieh, Daniel J., Deborah F. King, Katja Klein, Pinghuang Liu, Xiaoying Shen, Kwan Ki Hwang, Guido Ferrari, et al. “Aggregate complexes of HIV-1 induced by multimeric antibodies.” Retrovirology 11 (October 2, 2014): 78. https://doi.org/10.1186/s12977-014-0078-8.Full Text Open Access Copy Link to Item
-
Li, Shuying S., Peter B. Gilbert, Georgia D. Tomaras, Gustavo Kijak, Guido Ferrari, Rasmi Thomas, Chul-Woo Pyo, et al. “FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial.” J Clin Invest 124, no. 9 (September 2014): 3879–90. https://doi.org/10.1172/JCI75539.Full Text Link to Item
-
Payne, Tamika L., Jeff Blackinton, Alyse Frisbee, Joy Pickeral, Sheetal Sawant, Nathan A. Vandergrift, Stephanie A. Freel, Guido Ferrari, Jack D. Keene, and Georgia D. Tomaras. “Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition.” J Virol 88, no. 17 (September 1, 2014): 9514–28. https://doi.org/10.1128/JVI.00802-14.Full Text Link to Item
-
Dennison, S Moses, Kara M. Anasti, Frederick H. Jaeger, Shelley M. Stewart, Justin Pollara, Pinghuang Liu, Erika L. Kunz, et al. “Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide.” J Virol 88, no. 16 (August 2014): 9406–17. https://doi.org/10.1128/JVI.01031-14.Full Text Link to Item
-
Haynes, Barton F., M Anthony Moody, Munir Alam, Mattia Bonsignori, Laurent Verkoczy, Guido Ferrari, Feng Gao, Georgia D. Tomaras, Hua-Xin Liao, and Garnett Kelsoe. “Progress in HIV-1 vaccine development.” J Allergy Clin Immunol 134, no. 1 (July 2014): 3–10. https://doi.org/10.1016/j.jaci.2014.04.025.Full Text Link to Item
-
Pollara, Justin, Mattia Bonsignori, M Anthony Moody, Pinghuang Liu, S Munir Alam, Kwan-Ki Hwang, Thaddeus C. Gurley, et al. “HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities.” J Virol 88, no. 14 (July 2014): 7715–26. https://doi.org/10.1128/JVI.00156-14.Full Text Link to Item
-
Yates, Nicole L., Hua-Xin Liao, Youyi Fong, Allan deCamp, Nathan A. Vandergrift, William T. Williams, S Munir Alam, et al. “Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination.” Sci Transl Med 6, no. 228 (March 19, 2014): 228ra39. https://doi.org/10.1126/scitranslmed.3007730.Full Text Link to Item
-
Moody, M Anthony, Sampa Santra, Nathan A. Vandergrift, Laura L. Sutherland, Thaddeus C. Gurley, Mark S. Drinker, Ashley A. Allen, et al. “Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques.” J Virol 88, no. 6 (March 2014): 3329–39. https://doi.org/10.1128/JVI.03309-13.Full Text Link to Item
-
Roederer, Mario, Brandon F. Keele, Stephen D. Schmidt, Rosemarie D. Mason, Hugh C. Welles, Will Fischer, Celia Labranche, et al. “Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV.” Nature 505, no. 7484 (January 23, 2014): 502–8. https://doi.org/10.1038/nature12893.Full Text Open Access Copy Link to Item
-
Perley, Casey C., Marc Frahm, Eva M. Click, Karen M. Dobos, Guido Ferrari, Jason E. Stout, and Richard Frothingham. “The human antibody response to the surface of Mycobacterium tuberculosis.” Plos One 9, no. 2 (2014): e98938. https://doi.org/10.1371/journal.pone.0098938.Full Text Open Access Copy Link to Item
-
Liu, Pinghuang, Nicole L. Yates, Xiaoying Shen, Mattia Bonsignori, M Anthony Moody, Hua-Xin Liao, Youyi Fong, et al. “Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccinees.” J Virol 87, no. 14 (July 2013): 7828–36. https://doi.org/10.1128/JVI.02737-12.Full Text Open Access Copy Link to Item
-
Pollara, Justin, Mattia Bonsignori, M Anthony Moody, Marzena Pazgier, Barton F. Haynes, and Guido Ferrari. “Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses.” Curr Hiv Res 11, no. 5 (July 2013): 378–87. https://doi.org/10.2174/1570162x113116660059.Full Text Link to Item
-
Fouda, Genevieve G. A., Joshua D. Amos, Andrew B. Wilks, Justin Pollara, Caroline A. Ray, Anjali Chand, Erika L. Kunz, et al. “Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk.” J Virol 87, no. 12 (June 2013): 6986–99. https://doi.org/10.1128/JVI.00528-13.Full Text Link to Item
-
Tomaras, Georgia D., Guido Ferrari, Xiaoying Shen, S Munir Alam, Hua-Xin Liao, Justin Pollara, Mattia Bonsignori, et al. “Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG.” Proc Natl Acad Sci U S A 110, no. 22 (May 28, 2013): 9019–24. https://doi.org/10.1073/pnas.1301456110.Full Text Link to Item
-
Vaccari, Monica, Brandon F. Keele, Steven E. Bosinger, Melvin N. Doster, Zhong-Min Ma, Justin Pollara, Anna Hryniewicz, et al. “Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure.” J Virol 87, no. 6 (March 2013): 3538–48. https://doi.org/10.1128/JVI.02863-12.Full Text Link to Item
-
Pegu, Poonam, Monica Vaccari, Shari Gordon, Brandon F. Keele, Melvin Doster, Yongjun Guan, Guido Ferrari, et al. “Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial.” J Virol 87, no. 3 (February 2013): 1708–19. https://doi.org/10.1128/JVI.02544-12.Full Text Link to Item
-
Liao, Hua-Xin, Mattia Bonsignori, S Munir Alam, Jason S. McLellan, Georgia D. Tomaras, M Anthony Moody, Daniel M. Kozink, et al. “Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2.” Immunity 38, no. 1 (January 24, 2013): 176–86. https://doi.org/10.1016/j.immuni.2012.11.011.Full Text Link to Item
-
Weaver, Eric A., Pramod N. Nehete, Bharti P. Nehete, Guojun Yang, Stephanie J. Buchl, Patrick W. Hanley, Donna Palmer, et al. “Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV.” Plos One 8, no. 7 (2013): e67574. https://doi.org/10.1371/journal.pone.0067574.Full Text Link to Item
-
Lambotte, Olivier, Justin Pollara, Faroudy Boufassa, Christiane Moog, Alain Venet, Barton F. Haynes, Jean-François Delfraissy, Asier Saez-Cirion, and Guido Ferrari. “High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers.” Plos One 8, no. 9 (2013): e74855. https://doi.org/10.1371/journal.pone.0074855.Full Text Link to Item
-
Liu, Michael K. P., Natalie Hawkins, Adam J. Ritchie, Vitaly V. Ganusov, Victoria Whale, Simon Brackenridge, Hui Li, et al. “Vertical T cell immunodominance and epitope entropy determine HIV-1 escape.” J Clin Invest 123, no. 1 (January 2013): 380–93. https://doi.org/10.1172/JCI65330.Full Text Link to Item
-
McKellar, Mehri S., Anna B. Cope, Cynthia L. Gay, Kara S. McGee, Joann D. Kuruc, Melissa G. Kerkau, Christopher B. Hurt, et al. “Acute HIV-1 infection in the Southeastern United States: a cohort study.” Aids Res Hum Retroviruses 29, no. 1 (January 2013): 121–28. https://doi.org/10.1089/aid.2012.0064.Full Text Link to Item
-
Bonsignori, Mattia, Justin Pollara, M Anthony Moody, Michael D. Alpert, Xi Chen, Kwan-Ki Hwang, Peter B. Gilbert, et al. “Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family.” J Virol 86, no. 21 (November 2012): 11521–32. https://doi.org/10.1128/JVI.01023-12.Full Text Link to Item
-
Fukazawa, Yoshinori, Haesun Park, Mark J. Cameron, Francois Lefebvre, Richard Lum, Noel Coombes, Eisa Mahyari, et al. “Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines.” Nat Med 18, no. 11 (November 2012): 1673–81. https://doi.org/10.1038/nm.2934.Full Text Link to Item
-
Song, Hongshuo, Jeffrey W. Pavlicek, Fangping Cai, Tanmoy Bhattacharya, Hui Li, Shilpa S. Iyer, Katharine J. Bar, et al. “Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome.” Retrovirology 9 (October 30, 2012): 89. https://doi.org/10.1186/1742-4690-9-89.Full Text Link to Item
-
Arnoczy, Gretchen S., Guido Ferrari, Nilu Goonetilleke, Tumena Corrah, Hui Li, Joann Kuruc, John L. Schmitz, et al. “Massive CD8 T cell response to primary HIV infection in the setting of severe clinical presentation.” Aids Res Hum Retroviruses 28, no. 8 (August 2012): 789–92. https://doi.org/10.1089/AID.2011.0145.Full Text Link to Item
-
Britten, C. M., S. Janetzki, L. H. Butterfield, G. Ferrari, C. Gouttefangeas, C. Huber, M. Kalos, et al. “T cell assays and MIATA: the essential minimum for maximum impact.” Immunity 37, no. 1 (July 27, 2012): 1–2. https://doi.org/10.1016/j.immuni.2012.07.010.Full Text Link to Item
-
Moody, M Anthony, Nicole L. Yates, Joshua D. Amos, Mark S. Drinker, Joshua A. Eudailey, Thaddeus C. Gurley, Dawn J. Marshall, et al. “HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages.” J Virol 86, no. 14 (July 2012): 7496–7507. https://doi.org/10.1128/JVI.00426-12.Full Text Link to Item
-
Freel, Stephanie A., Ralph A. Picking, Guido Ferrari, Haitao Ding, Christina Ochsenbauer, John C. Kappes, Jennifer L. Kirchherr, et al. “Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication.” J Virol 86, no. 12 (June 2012): 6835–46. https://doi.org/10.1128/JVI.00437-12.Full Text Open Access Copy Link to Item
-
Frahm, Marc A., Ralph A. Picking, JoAnn D. Kuruc, Kara S. McGee, Cynthia L. Gay, Joseph J. Eron, Charles B. Hicks, Georgia D. Tomaras, and Guido Ferrari. “CD4+CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection.” J Immunol 188, no. 9 (May 1, 2012): 4289–96. https://doi.org/10.4049/jimmunol.1103701.Full Text Link to Item
-
Haynes, Barton F., Peter B. Gilbert, M Juliana McElrath, Susan Zolla-Pazner, Georgia D. Tomaras, S Munir Alam, David T. Evans, et al. “Immune-correlates analysis of an HIV-1 vaccine efficacy trial.” N Engl J Med 366, no. 14 (April 5, 2012): 1275–86. https://doi.org/10.1056/NEJMoa1113425.Full Text Link to Item
-
Riou, Catherine, Vitaly V. Ganusov, Suzanne Campion, Mandla Mlotshwa, Michael K. P. Liu, Victoria E. Whale, Nilu Goonetilleke, et al. “Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection.” J Immunol 188, no. 5 (March 1, 2012): 2198–2206. https://doi.org/10.4049/jimmunol.1102813.Full Text Link to Item
-
Cox, Josephine H., Maria G. Ferrari, Patricia Earl, James R. Lane, Linda L. Jagodzinski, Victoria R. Polonis, Ellen G. Kuta, et al. “Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge.” Vaccine 30, no. 10 (February 27, 2012): 1830–40. https://doi.org/10.1016/j.vaccine.2011.12.131.Full Text Link to Item
-
Lai, Lilin, Sue-Fen Kwa, Pamela A. Kozlowski, David C. Montefiori, Tracy L. Nolen, Michael G. Hudgens, Welkin E. Johnson, et al. “SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses.” Vaccine 30, no. 9 (February 21, 2012): 1737–45. https://doi.org/10.1016/j.vaccine.2011.12.026.Full Text Link to Item
-
Barouch, Dan H., Jinyan Liu, Hualin Li, Lori F. Maxfield, Peter Abbink, Diana M. Lynch, M Justin Iampietro, et al. “Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys.” Nature 482, no. 7383 (January 4, 2012): 89–93. https://doi.org/10.1038/nature10766.Full Text Link to Item
-
Friedman, James, S Munir Alam, Xiaoying Shen, Shi-Mao Xia, Shelley Stewart, Kara Anasti, Justin Pollara, et al. “Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum.” Plos One 7, no. 5 (2012): e37648. https://doi.org/10.1371/journal.pone.0037648.Full Text Open Access Copy Link to Item
-
Ganusov, Vitaly V., Nilu Goonetilleke, Michael K. P. Liu, Guido Ferrari, George M. Shaw, Andrew J. McMichael, Persephone Borrow, Bette T. Korber, and Alan S. Perelson. “Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection.” J Virol 85, no. 20 (October 2011): 10518–28. https://doi.org/10.1128/JVI.00655-11.Full Text Link to Item
-
Fouda, Genevieve G., Nicole L. Yates, Justin Pollara, Xiaoying Shen, Glenn R. Overman, Tatenda Mahlokozera, Andrew B. Wilks, et al. “HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies.” J Virol 85, no. 18 (September 2011): 9555–67. https://doi.org/10.1128/JVI.05174-11.Full Text Open Access Copy Link to Item
-
Pollara, Justin, Lydia Hart, Faraha Brewer, Joy Pickeral, Beverly Z. Packard, James A. Hoxie, Akira Komoriya, et al. “High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses.” Cytometry A 79, no. 8 (August 2011): 603–12. https://doi.org/10.1002/cyto.a.21084.Full Text Link to Item
-
Lai, Lilin, Suefen Kwa, Pamela A. Kozlowski, David C. Montefiori, Guido Ferrari, Welkin E. Johnson, Vanessa Hirsch, et al. “Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine.” J Infect Dis 204, no. 1 (July 1, 2011): 164–73. https://doi.org/10.1093/infdis/jir199.Full Text Link to Item
-
Ferrari, Guido, Justin Pollara, Daniel Kozink, Tiara Harms, Mark Drinker, Stephanie Freel, M Anthony Moody, et al. “An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum.” J Virol 85, no. 14 (July 2011): 7029–36. https://doi.org/10.1128/JVI.00171-11.Full Text Link to Item
-
Gay, Cynthia, Oliver Dibben, Jeffrey A. Anderson, Andrea Stacey, Ashley J. Mayo, Philip J. Norris, JoAnn D. Kuruc, et al. “Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy.” Plos One 6, no. 5 (May 10, 2011): e19617. https://doi.org/10.1371/journal.pone.0019617.Full Text Link to Item
-
Yamamoto, Takuya, David A. Price, Joseph P. Casazza, Guido Ferrari, Martha Nason, Pratip K. Chattopadhyay, Mario Roederer, et al. “Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection.” Blood 117, no. 18 (May 5, 2011): 4805–15. https://doi.org/10.1182/blood-2010-11-317297.Full Text Link to Item
-
Frahm, Marc, Neela D. Goswami, Kouros Owzar, Emily Hecker, Ann Mosher, Emily Cadogan, Payam Nahid, Guido Ferrari, and Jason E. Stout. “Discriminating between latent and active tuberculosis with multiple biomarker responses.” Tuberculosis (Edinb) 91, no. 3 (May 2011): 250–56. https://doi.org/10.1016/j.tube.2011.02.006.Full Text Link to Item
-
Gay, Cynthia L., Ashley J. Mayo, Chelu K. Mfalila, Haitao Chu, Anna C. Barry, JoAnn D. Kuruc, Kara S. McGee, et al. “Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection.” Aids 25, no. 7 (April 24, 2011): 941–49. https://doi.org/10.1097/QAD.0b013e3283463c07.Full Text Link to Item
-
Ganusov, Vitaly, Nilu Goonetilleke, Michael Liu, Guido Ferrari, George Shaw, Andrew McMichael, Persephone Borrow, Bette Korber, and Alan Perelson. “Fitness costs and diversity of CTL response determine the rate of CTL escape during the acute and chronic phases of HIV infection.” Journal of Immunology 186 (April 1, 2011).Link to Item
-
Keefer, Michael C., Sharon E. Frey, Marnie Elizaga, Barbara Metch, Stephen C. De Rosa, Paulo F. Barroso, Georgia Tomaras, et al. “A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects.” Vaccine 29, no. 10 (February 24, 2011): 1948–58. https://doi.org/10.1016/j.vaccine.2010.12.104.Full Text Link to Item
-
Ferrari, Guido, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, et al. “Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection.” Plos Pathog 7, no. 2 (February 10, 2011): e1001273. https://doi.org/10.1371/journal.ppat.1001273.Full Text Link to Item
-
Weinberg, Adriana, Lin Ye Song, Cindy L. Wilkening, Terry Fenton, John Hural, Raul Louzao, Guido Ferrari, et al. “Optimization of storage and shipment of cryopreserved peripheral blood mononuclear cells from HIV-infected and uninfected individuals for ELISPOT assays.” J Immunol Methods 363, no. 1 (December 15, 2010): 42–50. https://doi.org/10.1016/j.jim.2010.09.032.Full Text Link to Item
-
Graham, Barney S., M Juliana McElrath, Michael C. Keefer, Kyle Rybczyk, David Berger, Kent J. Weinhold, Janet Ottinger, et al. “Immunization with cocktail of HIV-derived peptides in montanide ISA-51 is immunogenic, but causes sterile abscesses and unacceptable reactogenicity.” Plos One 5, no. 8 (August 10, 2010): e11995. https://doi.org/10.1371/journal.pone.0011995.Full Text Open Access Copy Link to Item
-
Freel, Stephanie A., Laurie Lamoreaux, Pratip K. Chattopadhyay, Kevin Saunders, David Zarkowsky, R Glenn Overman, Christina Ochsenbauer, et al. “Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination.” J Virol 84, no. 10 (May 2010): 4998–5006. https://doi.org/10.1128/JVI.00138-10.Full Text Open Access Copy Link to Item
-
Cella, Marina, Rachel Presti, William Vermi, Kerry Lavender, Emma Turnbull, Christina Ochsenbauer-Jambor, John C. Kappes, et al. “Loss of DNAM-1 contributes to CD8+ T-cell exhaustion in chronic HIV-1 infection.” Eur J Immunol 40, no. 4 (April 2010): 949–54. https://doi.org/10.1002/eji.200940234.Full Text Link to Item
-
Janetzki, Sylvia, L. Price, C. M. Britten, S. H. van der Burg, J. Caterini, J. R. Currier, G. Ferrari, et al. “Performance of serum-supplemented and serum-free media in IFNgamma Elispot Assays for human T cells.” Cancer Immunol Immunother 59, no. 4 (April 2010): 609–18. https://doi.org/10.1007/s00262-009-0788-2.Full Text Link to Item
-
Makedonas, George, Natalie Hutnick, Danielle Haney, Alexandra C. Amick, Jay Gardner, Gabriela Cosma, Adam R. Hersperger, et al. “Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells.” Plos Pathog 6, no. 3 (March 5, 2010): e1000798. https://doi.org/10.1371/journal.ppat.1000798.Full Text Open Access Copy Link to Item
-
Goonetilleke, Nilu, Michael K. P. Liu, Jesus F. Salazar-Gonzalez, Guido Ferrari, Elena Giorgi, Vitaly V. Ganusov, Brandon F. Keele, et al. “The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection.” J Exp Med 206, no. 6 (June 8, 2009): 1253–72. https://doi.org/10.1084/jem.20090365.Full Text Link to Item
-
Lambotte, Olivier, Guido Ferrari, Christiane Moog, Nicole L. Yates, Hua-Xin Liao, Robert J. Parks, Charles B. Hicks, et al. “Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers.” Aids 23, no. 8 (May 15, 2009): 897–906. https://doi.org/10.1097/QAD.0b013e328329f97d.Full Text Link to Item
-
Wood, Natasha, Tanmoy Bhattacharya, Brandon F. Keele, Elena Giorgi, Michael Liu, Brian Gaschen, Marcus Daniels, et al. “HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC.” Plos Pathog 5, no. 5 (May 2009): e1000414. https://doi.org/10.1371/journal.ppat.1000414.Full Text Link to Item
-
Spearman, Paul, Spyros Kalams, Marnie Elizaga, Barbara Metch, Ya-Lin Chiu, Mary Allen, Kent J. Weinhold, et al. “Safety and immunogenicity of a CTL multiepitope peptide vaccine for HIV with or without GM-CSF in a phase I trial.” Vaccine 27, no. 2 (January 7, 2009): 243–49. https://doi.org/10.1016/j.vaccine.2008.10.051.Full Text Link to Item
-
Gasper-Smith, Nancy, Deanna M. Crossman, John F. Whitesides, Nadia Mensali, Janet S. Ottinger, Steven G. Plonk, M Anthony Moody, et al. “Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design.” J Virol 82, no. 15 (August 2008): 7700–7710. https://doi.org/10.1128/JVI.00605-08.Full Text Link to Item
-
DREAM Trial Investigators, S., G. R. Dagenais, H. C. Gerstein, R. Holman, A. Budaj, A. Escalante, T. Hedner, et al. “Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial.” Diabetes Care 31, no. 5 (May 2008): 1007–14. https://doi.org/10.2337/dc07-1868.Full Text Link to Item
-
Gorse, Geoffrey J., Lindsey R. Baden, Margaret Wecker, Mark J. Newman, Guido Ferrari, Kent J. Weinhold, Brian D. Livingston, et al. “Safety and immunogenicity of cytotoxic T-lymphocyte poly-epitope, DNA plasmid (EP HIV-1090) vaccine in healthy, human immunodeficiency virus type 1 (HIV-1)-uninfected adults.” Vaccine 26, no. 2 (January 10, 2008): 215–23. https://doi.org/10.1016/j.vaccine.2007.10.061.Full Text Link to Item
-
Montefiori, David C., Lynn Morris, Guido Ferrari, and John R. Mascola. “Neutralizing and other antiviral antibodies in HIV-1 infection and vaccination.” Curr Opin Hiv Aids 2, no. 3 (May 2007): 169–76. https://doi.org/10.1097/COH.0b013e3280ef691e.Full Text Link to Item
-
Russell, Nina D., Barney S. Graham, Michael C. Keefer, M Juliana McElrath, Steve G. Self, Kent J. Weinhold, David C. Montefiori, et al. “Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial.” J Acquir Immune Defic Syndr 44, no. 2 (February 1, 2007): 203–12. https://doi.org/10.1097/01.qai.0000248356.48501.ff.Full Text Link to Item
-
Goepfert, Paul A., Georgia D. Tomaras, Helen Horton, David Montefiori, Guido Ferrari, Mark Deers, Gerald Voss, et al. “Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers.” Vaccine 25, no. 3 (January 5, 2007): 510–18. https://doi.org/10.1016/j.vaccine.2006.07.050.Full Text Link to Item
-
DREAM Trial Investigators, Rury R., Jackie Bosch, Salim Yusuf, Hertzel C. Gerstein, Janice Pogue, Patrick Sheridan, Gilles Dagenais, et al. “Effect of ramipril on the incidence of diabetes.” N Engl J Med 355, no. 15 (October 12, 2006): 1551–62. https://doi.org/10.1056/NEJMoa065061.Full Text Link to Item
-
Betts, Michael R., Clive M. Gray, Josephine H. Cox, and Guido Ferrari. “Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development.” Expert Rev Vaccines 5, no. 4 (August 2006): 505–16. https://doi.org/10.1586/14760584.5.4.505.Full Text Link to Item
-
Mulligan, M. J., N. D. Russell, C. Celum, J. Kahn, E. Noonan, D. C. Montefiori, G. Ferrari, et al. “Excellent safety and tolerability of the human immunodeficiency virus type 1 pGA2/JS2 plasmid DNA priming vector vaccine in HIV type 1 uninfected adults.” Aids Res Hum Retroviruses 22, no. 7 (July 2006): 678–83. https://doi.org/10.1089/aid.2006.22.678.Full Text Link to Item
-
Cox, Josephine H., Guido Ferrari, and Sylvia Janetzki. “Measurement of cytokine release at the single cell level using the ELISPOT assay.” Methods 38, no. 4 (April 2006): 274–82. https://doi.org/10.1016/j.ymeth.2005.11.006.Full Text Link to Item
-
Goepfert, Paul A., Helen Horton, M Juliana McElrath, Sanjay Gurunathan, Guido Ferrari, Georgia D. Tomaras, David C. Montefiori, et al. “High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects.” J Infect Dis 192, no. 7 (October 1, 2005): 1249–59. https://doi.org/10.1086/432915.Full Text Link to Item
-
Sempowski, Gregory D., Charles B. Hicks, Joseph J. Eron, John A. Bartlett, Laura P. Hale, Guido Ferrari, Lloyd J. Edwards, Susan Fiscus, and Barton F. Haynes. “Naïve T cells are maintained in the periphery during the first 3 months of acute HIV-1 infection: implications for analysis of thymus function.” J Clin Immunol 25, no. 5 (September 2005): 462–72. https://doi.org/10.1007/s10875-005-5635-4.Full Text Link to Item
-
Betts, Michael R., Barbara Exley, David A. Price, Anju Bansal, Zenaido Tres Camacho, Vanessa Teaberry, Sadie M. West, et al. “Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection.” Proc Natl Acad Sci U S A 102, no. 12 (March 22, 2005): 4512–17. https://doi.org/10.1073/pnas.0408773102.Full Text Link to Item
-
Currier, Jeffrey R., Matthew E. Harris, Josephine H. Cox, Francine E. McCutchan, Deborah L. Birx, Shlomo Maayan, and Guido Ferrari. “Immunodominance and cross-reactivity of B5703-restricted CD8 T lymphocytes from HIV type 1 subtype C-infected Ethiopians.” Aids Res Hum Retroviruses 21, no. 3 (March 2005): 239–45. https://doi.org/10.1089/aid.2005.21.239.Full Text Link to Item
-
Cox, Josephine H., Guido Ferrari, Spyros A. Kalams, Wlodek Lopaczynski, Neal Oden, M Patricia D’souza, and M Patricia Elispot Collaborative Study Group. “Results of an ELISPOT proficiency panel conducted in 11 laboratories participating in international human immunodeficiency virus type 1 vaccine trials.” Aids Res Hum Retroviruses 21, no. 1 (January 2005): 68–81. https://doi.org/10.1089/aid.2005.21.68.Full Text Link to Item
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Kaplan, Susan S., Guido Ferrari, Terri Wrin, Nicholas S. Hellmann, Georgia D. Tomaras, Victoria E. Gryszowka, Susan A. Fiscus, Kent J. Weinhold, and Charles B. Hicks. “Longitudinal assessment of immune response and viral characteristics in HIV-infected patients with prolonged CD4(+)/viral load discordance.” Aids Res Hum Retroviruses 21, no. 1 (January 2005): 13–16. https://doi.org/10.1089/aid.2005.21.13.Full Text Link to Item
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Janetzki, Sylvia, Josephine H. Cox, Neal Oden, and Guido Ferrari. “Standardization and validation issues of the ELISPOT assay.” Methods Mol Biol 302 (2005): 51–86. https://doi.org/10.1385/1-59259-903-6:051.Full Text Link to Item
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Ferrari, Guido, Wesley Neal, Janet Ottinger, Anizsa M. Jones, Bradley H. Edwards, Paul Goepfert, Michael R. Betts, et al. “Absence of immunodominant anti-Gag p17 (SL9) responses among Gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 allele.” J Immunol 173, no. 3 (August 1, 2004): 2126–33. https://doi.org/10.4049/jimmunol.173.3.2126.Full Text Link to Item
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Ferrari, Guido, Jeffrey R. Currier, Matthew E. Harris, Stella Finkelstein, Angelica de Oliveira, Debra Barkhan, Josephine H. Cox, et al. “HLA-A and -B allele expression and ability to develop anti-Gag cross-clade responses in subtype C HIV-1-infected Ethiopians.” Hum Immunol 65, no. 6 (June 2004): 648–59. https://doi.org/10.1016/j.humimm.2004.02.031.Full Text Link to Item
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Cox, J. H., G. Ferrari, R. T. Bailer, and R. A. Koup. “Automating Procedures for Processing, Cryopreservation, Storage, and Manipulation of Human Peripheral Blood Mononuclear Cells.” Journal of Laboratory Automation 9, no. 1 (January 1, 2004): 16–23. https://doi.org/10.1016/S1535-5535-03-00202-8.Full Text
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Harris, Matthew E., Shlomo Maayan, Bohye Kim, Michael Zeira, Guido Ferrari, Deborah L. Birx, and Francine E. McCutchan. “A cluster of HIV type 1 subtype C sequences from Ethiopia, observed in full genome analysis, is not sustained in subgenomic regions.” Aids Res Hum Retroviruses 19, no. 12 (December 2003): 1125–33. https://doi.org/10.1089/088922203771881220.Full Text Link to Item
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Sufka, Susan A., Guido Ferrari, Victoria E. Gryszowka, Terri Wrin, Susan A. Fiscus, Georgia D. Tomaras, Herman F. Staats, et al. “Prolonged CD4+ cell/virus load discordance during treatment with protease inhibitor-based highly active antiretroviral therapy: immune response and viral control.” J Infect Dis 187, no. 7 (April 1, 2003): 1027–37. https://doi.org/10.1086/368359.Full Text Link to Item
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Currier, Jeffrey R., Ellen G. Kuta, Ellen Turk, Lyndsay B. Earhart, Larry Loomis-Price, Sylvia Janetzki, Guido Ferrari, Deborah L. Birx, and Josephine H. Cox. “A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays.” J Immunol Methods 260, no. 1–2 (February 1, 2002): 157–72. https://doi.org/10.1016/s0022-1759(01)00535-x.Full Text Link to Item
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Ferrari, G., W. Neal, A. Jones, N. Olender, J. Ottinger, R. Ha, M. J. McElrath, P. Goepfert, and K. J. Weinhold. “CD8 CTL responses in vaccines: emerging patterns of HLA restriction and epitope recognition.” Immunol Lett 79, no. 1–2 (November 1, 2001): 37–45. https://doi.org/10.1016/s0165-2478(01)00264-4.Full Text Link to Item
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Ferrari, G., D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. “Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines.” Aids Res Hum Retroviruses 16, no. 14 (September 20, 2000): 1433–43. https://doi.org/10.1089/08892220050140982.Full Text Link to Item
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Tomaras, G. D., S. F. Lacey, C. B. McDanal, G. Ferrari, K. J. Weinhold, and M. L. Greenberg. “CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression.” Proc Natl Acad Sci U S A 97, no. 7 (March 28, 2000): 3503–8. https://doi.org/10.1073/pnas.97.7.3503.Full Text Link to Item
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Markert, M. L., C. B. Hicks, J. A. Bartlett, J. L. Harmon, L. P. Hale, M. L. Greenberg, G. Ferrari, et al. “Effect of highly active antiretroviral therapy and thymic transplantation on immunoreconstitution in HIV infection.” Aids Res Hum Retroviruses 16, no. 5 (March 20, 2000): 403–13. https://doi.org/10.1089/088922200309061.Full Text Link to Item
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Falk, Lydia A., Karen L. Goldenthal, Jose Esparza, M Teresa Aguado, Saladin Osmanov, and W Ripley Ballou. “Recombinant Bacillus Calmette-Guerin as a Potential Vector for Preventive HIV Type 1 Vaccines.” Aids Research and Human Retroviruses 16, no. 2 (January 20, 2000): 91–98. https://doi.org/10.1089/088922200309421.Full Text
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Stranford, S. A., J. Skurnick, D. Louria, D. Osmond, S. Y. Chang, J. Sninsky, G. Ferrari, K. Weinhold, C. Lindquist, and J. A. Levy. “Lack of infection in HIV-exposed individuals is associated with a strong CD8(+) cell noncytotoxic anti-HIV response.” Proc Natl Acad Sci U S A 96, no. 3 (February 2, 1999): 1030–35. https://doi.org/10.1073/pnas.96.3.1030.Full Text Link to Item
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Ferrari, G., C. Berend, J. Ottinger, R. Dodge, J. Bartlett, J. Toso, D. Moody, et al. “Replication-defective canarypox (ALVAC) vectors effectively activate anti-human immunodeficiency virus-1 cytotoxic T lymphocytes present in infected patients: implications for antigen-specific immunotherapy.” Blood 90, no. 6 (September 15, 1997): 2406–16.Link to Item
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Ferrari, G., W. Humphrey, M. J. McElrath, J. L. Excler, A. M. Duliege, M. L. Clements, L. C. Corey, D. P. Bolognesi, and K. J. Weinhold. “Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers.” Proc Natl Acad Sci U S A 94, no. 4 (February 18, 1997): 1396–1401. https://doi.org/10.1073/pnas.94.4.1396.Full Text Link to Item
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Toso, J. F., C. H. Chen, J. R. Mohr, L. Piglia, C. Oei, G. Ferrari, M. L. Greenberg, and K. J. Weinhold. “Oligoclonal CD8 lymphocytes from persons with asymptomatic human immunodeficiency virus (HIV) type 1 infection inhibit HIV-1 replication.” J Infect Dis 172, no. 4 (October 1995): 964–73. https://doi.org/10.1093/infdis/172.4.964.Full Text Link to Item
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Ferrari, G., K. King, K. Rathbun, C. A. Place, M. V. Packard, J. A. Bartlett, D. P. Bolognesi, and K. J. Weinhold. “IL-7 enhancement of antigen-driven activation/expansion of HIV-1-specific cytotoxic T lymphocyte precursors (CTLp).” Clin Exp Immunol 101, no. 2 (August 1995): 239–48. https://doi.org/10.1111/j.1365-2249.1995.tb08345.x.Full Text Link to Item
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Ferrari, G., C. A. Place, P. M. Ahearne, S. M. Nigida, L. O. Arthur, D. P. Bolognesi, and K. J. Weinhold. “Comparison of anti-HIV-1 ADCC reactivities in infected humans and chimpanzees.” J Acquir Immune Defic Syndr (1988) 7, no. 4 (April 1994): 325–31.Link to Item
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Ferrari, G., J. Ottinger, C. Place, S. M. Nigida, L. O. Arthur, and K. J. Weinhold. “The impact of HIV-1 infection on phenotypic and functional parameters of cellular immunity in chimpanzees.” Aids Res Hum Retroviruses 9, no. 7 (July 1993): 647–56. https://doi.org/10.1089/aid.1993.9.647.Full Text Link to Item
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Boeri, E., A. Giri, F. Lillo, G. Ferrari, O. E. Varnier, A. Ferro, S. Sabbatani, W. C. Saxinger, and G. Franchini. “In vivo genetic variability of the human immunodeficiency virus type 2 V3 region.” J Virol 66, no. 7 (July 1992): 4546–50. https://doi.org/10.1128/JVI.66.7.4546-4550.1992.Full Text Link to Item
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CANESSA, A., F. PANTAROTTO, F. MILETICH, A. RUSSO, C. GOTTA, P. M. BOZZUFFI, G. FERRARI, A. FIORELLI, and A. TERRAGNA. “ANTIBODY PREVALENCE TO TORCH AGENTS IN PREGNANT-WOMEN AND RELATIVE RISK OF CONGENITAL INFECTIONS IN ITALY (LIGURIA).” Biological Research in Pregnancy and Perinatology 8, no. 2 (January 1, 1987): 84–88.Link to Item
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Canessa, A., F. Pantarotto, F. Miletich, A. Russo, C. Gotta, P. M. Bozzuffi, G. Ferrari, A. Fiorelli, and A. Terragna. “Antibody prevalence to torch agents in pregnant women and relative risk of congenital infections in Italy (Liguria).” Biol Res Pregnancy Perinatol 8, no. 2 2D Half (1987): 84–88.Link to Item
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Book Sections
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D’Souza, P., J. H. Cox, G. Ferrari, N. T. Kunwar, V. Polonis, and M. Sarzotti-Kelsoe. “Endpoint Assays in HIV-1 Vaccine Trials: Functioning in a Good Laboratory Practices Environment.” In Validation of Cell-Based Assays in the GLP Setting: A Practical Guide, 239–75, 2008. https://doi.org/10.1002/9780470987810.ch14.Full Text
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Cox, Josephine H., Mark deSouza, Silvia Ratto-Kim, Guido Ferrari, Kent J. Weinhold, and Deborah L. Birx. “Cellular Immune Assays for Evaluation of Vaccine Efficacy.” In MANUAL OF MOLECULAR AND CLINICAL LABORATORY IMMUNOLOGY, 7TH EDITION, 301–14, 2006.Link to Item
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Other Articles
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Kvistborg, Pia, Cécile Gouttefangeas, Nima Aghaeepour, Angelica Cazaly, Pratip K. Chattopadhyay, Cliburn Chan, Judith Eckl, et al. “Thinking outside the gate: single-cell assessments in multiple dimensions.” Immunity, April 21, 2015. https://doi.org/10.1016/j.immuni.2015.04.006.Full Text Link to Item
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Frahm, M. A., G. D. Tomaras, and G. Ferrari. “Response to comment on "CD4 +CD8 + T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection".” Journal of Immunology, June 15, 2012. https://doi.org/10.4049/jimmunol.1290029.Full Text
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Rodenburg, C. M., Y. Li, S. A. Trask, Y. Chen, J. Decker, D. L. Robertson, M. L. Kalish, et al. “Near full-length clones and reference sequences for subtype C isolates of HIV type 1 from three different continents.” Aids Res Hum Retroviruses, January 20, 2001. https://doi.org/10.1089/08892220150217247.Full Text Link to Item
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Conference Papers
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Kenny, A., A. Luedtke, O. Hyrien, Y. Fong, R. Burnham, J. Heptinstall, S. Sawant, et al. “Immune correlates analysis of the Imbokodo HIV-1 vaccine efficacy trial.” In Journal of the International Aids Society, 25:214–214, 2022.Link to Item
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Nordstrom, J. L., C. L. Gay, C. Bohac, A. R. Wahl, T. Morgan, J. L. Schmitz, H. Li, et al. “In vivo preclinical efficacy of MGD014 and MGD020 (HIV-1 envelope x CD3 DART molecules) and first-in-human phase 1 clinical safety evaluation of MGD014.” In Journal of the International Aids Society, 25:6–7, 2022.Link to Item
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Singh, V., D. Burgess, A. Dashti, J. McBrien, H. King, R. Mason, J. Safrit, et al. “CD8 depletion and N-803 plus anti-SIV Env RhmAbs in ART-suppressed rhesus macaques.” In Journal of the International Aids Society, 25:237–237, 2022.Link to Item
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Spreng, Rachel, Marina Tuyishime, Brady Hueber, Junsuke Nohara, Derrick Goodman, Cliburn Chan, R Whitney Edwards, et al. “Multivariate analysis of FcR-mediated NK cell functions identifies unique clustering among Rhesus macaques.” In Journal of Medical Primatology, 51:312–312, 2022.Link to Item
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Margolis, D. M., K. S. James, M. Tuyishime, S. D. Falcinelli, S. B. Joseph, B. Allard, J. L. Kirchherr, et al. “Combination therapy with the broadly neutralizing antibody VRC07-523LS and the latency reversal agent Vorinostat fails to substantially reduce latent, resting CD4+T cell infection or reduce low-level viremia.” In Journal of the International Aids Society, 24:69–69, 2021.Link to Item
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Tuyishime, M., C. Garrido, S. Jha, M. Moeser, D. Mielke, C. LaBranche, D. Montefiori, et al. “Improved killing of HIV-infected cells by a combination of three neutralizing and non-neutralizing antibodies.” In Journal of the International Aids Society, Vol. 24, 2021.Link to Item
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Msafiri, Frank, Agricola Joachim, Kathrin Held, Yuka Nadai, Raquel Matavele Chissumba, Christof Geldmacher, Said Aboud, et al. “Frequent Anti-V1V2 Responses Induced by HIV-DNA Followed by HIV-MVA with or without CN54rgp140/GLA-AF in Healthy African Volunteers.” In Microorganisms, Vol. 8, 2020. https://doi.org/10.3390/microorganisms8111722.Full Text Link to Item
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Dashti, Amir, Chevaughn Waller, Maud Mavigner, Nils Schoof, Katharine J. Bar, George M. Shaw, Thomas H. Vanderford, et al. “SMAC Mimetic Plus Triple-Combination Bispecific HIVxCD3 Retargeting Molecules in SHIV.C.CH505-Infected, Antiretroviral Therapy-Suppressed Rhesus Macaques.” In J Virol, Vol. 94, 2020. https://doi.org/10.1128/JVI.00793-20.Full Text Link to Item
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Curtis, Alan Dale, Maria Dennis, Joshua Eudailey, Kenneth Cronin, Justin Pollara, Guido Ferrari, Michael Hudgens, Koen Van Rompay, Sallie Permar, and Kristina De Paris. “Neonatal vaccination primes persistent HIV Env-specific antibodies that are augmented by a single booster immunization in late infancy.” In Journal of Immunology, Vol. 204, 2020.Link to Item
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Felber, B. K., Z. Lu, X. Hu, A. Valentin, M. Rosati, J. A. Weiner, X. Shen, et al. “Co-immunization of DNA and protein in the same anatomical sites induces superior protective immune responses against SHIV challenge.” In Journal of the International Aids Society, 23:7–7, 2020.Link to Item
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Jones, Rebecca, Eric Scott, LaShanda Cheston, Morgan Gladden, Shalini Jha, Charles Beck, Justin Pollara, et al. “Vaccine-elicited memory B cells expressing ADCC-mediating antibodies lacking recognition of the V2 region did not correlate with protection of NHPs.” In Journal of Medical Primatology, 49:247–48, 2020.Link to Item
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Zaffiri, L., J. E. Messinger, J. Yi, K. J. Weinhold, G. Ferrari, M. Luftig, and S. M. Palmer. “Evaluation of Host Immune Responses to Epstein-Barr Virus in Lung Transplant Recipients.” In American Journal of Transplantation, 20:396–396, 2020.Link to Item
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Asbach, Benedikt, Karen V. Kibler, Josef Köstler, Beatriz Perdiguero, Nicole L. Yates, Sherry Stanfield-Oakley, Georgia D. Tomaras, et al. “Priming with a Potent HIV-1 DNA Vaccine Frames the Quality of Immune Responses prior to a Poxvirus and Protein Boost.” In J Virol, Vol. 93, 2019. https://doi.org/10.1128/JVI.01529-18.Full Text Link to Item
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Felber, Barbara, Shakti Singh, Antonio Valentin, Margherita Rosati, Eric Ramierz, Rami Doueiri, Xintao Hu, et al. “DNA and protein co-delivery vaccines using TLR-4-based adjuvants induce potent immune responses able to delay heterologous SIV acquisition.” In Journal of Medical Primatology, 47:313–313. WILEY, 2018.Link to Item
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Mielke, Dieter, Rutendo Ziki, Colin Anthony, Christina Ochsenbauer, Nigel Garrett, Salim S Abdool Karim, David Montefiori, et al. “Neutralizing and ADCC Activity of Anti-HIV-1 Antibodies Against Acute Subtype C Envs: Implications for Prevention and Treatment of HIV-1 Infection.” In Aids Research and Human Retroviruses, 34:53–53. MARY ANN LIEBERT, INC, 2018.Link to Item
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Phillips, Bonnie, Genevieve Fouda, Justin Pollara, Pamela Kozlowski, Anthony Moody, Guido Ferrari, Sallie Permar, and Kristina De Parisi. “The optimization of pediatric vaccine regimens to prevent mother-to-child transmission of HIV through breast milk.” In Journal of Medical Primatology, 47:344–45. WILEY, 2018.Link to Item
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Pollara, Justin, Dorothy I. Jones, Tori Huffman, Maria Dennis, Grace Li, Derrick Goodman, R Whitney Edwards, et al. “Bridging Vaccine-induced Antibody Responses in Rabbit and Rhesus Macaque Animal Models.” In Aids Research and Human Retroviruses, 34:129–129. MARY ANN LIEBERT, INC, 2018.Link to Item
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Shen, Xiaoying, Zoe Moodie, Arthur McMillan, Derrick Goodman, Nicole Yates, Rachel Spreng, Nicole Grunenberg, et al. “V1V2 IgG and Antibody Fc Effector Functions in a Subtype C ALVAC-HIV and Bivalent Subtype C gp120/MF59 HIV-1 Vaccine Trial in South Africa.” In Aids Research and Human Retroviruses, 34:17–17. MARY ANN LIEBERT, INC, 2018.Link to Item
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Tuyishime, Marina, Carolina Garrido, Shalini Jha, Anthony DeVico, Barton Haynes, David Margolis, and Guido Ferrari. “Recognition and Elimination of HIV-1-infected Cells by ADCC-mediating mAbs for Prevention and Treatment of HIV-1 Infection.” In Aids Research and Human Retroviruses, 34:126–126. MARY ANN LIEBERT, INC, 2018.Link to Item
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Wang, Shixia, Justin Pollara, Sherry Stanfield-Oakley, Diego Farfan-Arribas, Shuying Liu, Guido Ferrari, and Shan Lu. “Cross-clade ADCC Activities in Human Volunteer Sera Elicited by a Polyvalent DNA Prime-protein Boost HIV Vaccine DP6-001.” In Aids Research and Human Retroviruses, 34:129–129. MARY ANN LIEBERT, INC, 2018.Link to Item
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Williams, LaTonya, Matthew Zirui Tay, Xiaoying Shen, Sheetal Sawant, Lindsay Dahora, Nicole Yates, David Easterhoff, et al. “Delayed and Repetitive Boosting of RV144 Vaccinees Improves Antiviral Immunity Associated With Correlates of HIV-1 Infection Risk.” In Aids Research and Human Retroviruses, 34:88–88. MARY ANN LIEBERT, INC, 2018.Link to Item
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Ferrari, Guido, Jeffrey Nordstrom, Scott Koenig, Julia Sung, David Margolis, and Barton Haynes. “A-102 Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 77:33–33. Ovid Technologies (Wolters Kluwer Health), 2018. https://doi.org/10.1097/01.qai.0000532483.69631.d6.Full Text
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Buchbinder, Susan, Nicole Grunenberg, Brittany Sanchez, Kelly Seaton, Guido Ferrari, M Anthony Moody, Nicole Frahm, et al. “DNA/MVA HIV Vaccine Producing Virus-like Particles (VLPs) Is Well-tolerated and Induces Durable Functional Antibodies (Abs) in HVTN 094.” In Aids Research and Human Retroviruses, 32:99–99. MARY ANN LIEBERT, INC, 2016.Link to Item
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Huang, Ying, Georgia Tomaras, Erica Andersen-Nissen, One Dintwe, Lynn Morris, Nicole Grunenberg, Abby Issacs, et al. “The Relationship between Immune Responses to Tetanus Vaccine, Hepatitis B Vaccine and a Pox-protein HIV Vaccine Regimen.” In Aids Research and Human Retroviruses, 32:76–76. MARY ANN LIEBERT, INC, 2016.Link to Item
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Shen, Xiaoying, Rahul Basu, Suefen Kwa, Celia Labranche, David Beaumont, Guido Ferrari, Linda Wyatt, et al. “MVA-expressed gp140 Boosts More Durable V1/V2 and gp120 Antibody Responses than gp120 Protein in Alum.” In Aids Research and Human Retroviruses, 32:59–59. MARY ANN LIEBERT, INC, 2016.Link to Item
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Clutton, Genevieve Tyndale, Yinyan Xu, Maria Abad Fernandez, Amanda Crooks, Blair Turner, Nicole Maponga, Anna Cope, et al. “Effects of different treatment regimens on T cell function in acute HIV infection.” In Journal of Immunology, Vol. 196. AMER ASSOC IMMUNOLOGISTS, 2016.Link to Item
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Prentice, Heather, Georgia Tomaras, Daniel Geraghty, Richard Apps, Youyi Fong, Philip Ehrenberg, Morgane Rolland, et al. “HIV-1-specific IgG antibody levels correlate with the presence of a specific HLA class II allele to impact acquisition and vaccine efficacy.” In Journal of the International Aids Society, Vol. 18. JOHN WILEY & SONS LTD, 2015. https://doi.org/10.7448/IAS.18.5.20541.Full Text Link to Item
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Swiderska-Syn, M., S. Choi, A. Lan, G. Ferrari, A. M. Diehl, and S. Naggie. “P0469 : Markers of tissue repair and cellular aging are increased in liver tissue of patients with dual chronic HIV/HCV infections.” In Journal of Hepatology, 62:S489–S489. Elsevier BV, 2015. https://doi.org/10.1016/s0168-8278(15)30677-2.Full Text
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Fourati, S., M. Vaccari, S. N. Gordon, L. Schifanella, M. Cameron, B. F. Keele, X. Shen, et al. “Modulation of RAS Pathways as a Biomarker of Protection against HIV and as a Means to Improve Vaccine Efficacy.” In Aids Res Hum Retroviruses, 30 Suppl 1:A99, 2014. https://doi.org/10.1089/aid.2014.5182b.abstract.Full Text Link to Item
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Vaccari, M., S. N. Gordon, S. Fourati, L. Schifanella, M. Cameron, B. F. Keele, X. Shen, et al. “Adjuvant Dependent Mucosal V2 Responses and RAS Activation in Vaccine Induced Protection from SIVmac251 Acquisition.” In Aids Res Hum Retroviruses, 30 Suppl 1:A64–65, 2014. https://doi.org/10.1089/aid.2014.5117.abstract.Full Text Link to Item
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Fouda, G., J. Pollara, E. McGuire, W. Rountree, G. Overman, G. Tegha, D. Kamwendo, et al. “Association of HIV-1 Env Antibody Responses with Postnatal Mother-to-Child Transmission of HIV-1 via Breastfeeding.” In Aids Res Hum Retroviruses, 30 Suppl 1:A99–100, 2014. https://doi.org/10.1089/aid.2014.5182c.abstract.Full Text Link to Item
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Moody, M. A., D. Easterhoff, T. C. Gurley, J. F. Whitesides, D. J. Marshall, A. Foulger, K. E. Lloyd, et al. “Induction of Antibodies with Long Variable Heavy Third Complementarity Determining Regions by Repetitive Boosting with AIDSVAX® B/E in RV144 Vaccinees.” In Aids Res Hum Retroviruses, 30 Suppl 1:A36, 2014. https://doi.org/10.1089/aid.2014.5057a.abstract.Full Text Link to Item
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Ackerman, M. E., Y. Huang, G. Alter, G. Ferrari, D. Forthal, J. Kappes, G. Lewis, et al. “Comparative Evaluation of Assays for Fc Receptor-Mediated Antibody Effector Functions Targeting HIV-1.” In Aids Research and Human Retroviruses, 29:A169–A169. MARY ANN LIEBERT, INC, 2013.Link to Item
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Chege, G. K., D. C. Montefiori, S. Barnett, C. M. Gray, W. A. Burgers, T. L. Muller, E. G. Shephard, C. Williamson, G. Ferrari, and A. Williamson. “A Combined Saavi MVA-C and Novartis Gp140 Env Protein Vaccine Boost Elicits Robust HIV Cellular and Humoral Responses in a Nonhuman Primate Model.” In Aids Research and Human Retroviruses, 29:A39–A39. MARY ANN LIEBERT, INC, 2013.Link to Item
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Gao, F., M. Bonsignori, H. Liao, A. Kumar, S. Xia, F. Cai, X. Lu, et al. “Multiple Pathways of HIV-1 Autologous Neutralizing Antibodies Cooperate to Drive CD4 Binding Site Broadly Neutralizing Antibody Responses.” In Aids Research and Human Retroviruses, 29:A186–A186. MARY ANN LIEBERT, INC, 2013.Link to Item
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Gordon, S. N., M. Vaccari, M. N. Doster, N. P. Liyanage, P. Pegu, L. Schifanella, F. Caccuri, et al. “Priming with Adenovirus26 Vaccines Affects ALVAC-SIV/gp120 Vaccine Efficacy Tested in a SIVmac251 Challenge Model Performed One-Month Post-Vaccination.” In Aids Research and Human Retroviruses, 29:A39–A39. MARY ANN LIEBERT, INC, 2013.Link to Item
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Joachim, A., P. Munseri, C. Nilsson, M. Bakari, S. Aboud, E. F. Lyamuya, C. Moshiro, et al. “A Late Third HIV-MVA Vaccination Boosted Strong and Potent Immune Responses in Tanzanian Volunteers Previously Immunized with HIV-DNA and HIV-MVA.” In Aids Research and Human Retroviruses, 29:A174–A174. MARY ANN LIEBERT, INC, 2013.Link to Item
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Li, S. S., P. B. Gilbert, G. D. Tomaras, G. Kijak, G. Ferrari, R. Thomas, S. Zolla-Pazner, et al. “Association of Fc gamma RIIC Polymorphism with Vaccine Efficacy and Correlates of HIV-1 Infection Risk in RV144.” In Aids Research and Human Retroviruses, 29:A178–79. MARY ANN LIEBERT, INC, 2013.Link to Item
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Pollara, J., M. Bonsignori, M. Moody, S. Alam, K. Hwang, T. C. Gurley, D. M. Kozink, et al. “Heterogeneity of Anti-V2 ADCC Ab Responses and Implications for Vaccine Development.” In Aids Research and Human Retroviruses, 29:A41–A41. MARY ANN LIEBERT, INC, 2013.Link to Item
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Schifanella, L., S. Gordon, M. Vaccari, N. Binello, F. Caccuri, M. Blackburn, C. Fenizia, et al. “MF59 and ALUM, in Combination with an ALVAC-SIV/gp120 Vaccine, Induce Plasmablasts that Differ in the Expression of Homing Markers.” In Aids Research and Human Retroviruses, 29:A13–A13. MARY ANN LIEBERT, INC, 2013.Link to Item
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Vaccari, M., S. N. Gordon, M. Doster, N. Liynage, P. Pegu, L. Schifanella, B. F. Keele, et al. “Protection from SIVmac251 Acquisition by an ALVAC/SIV/gp120 Regimen Is Not Improved by the Increase of Anti-Envelope Antibodies and T Cell Responses.” In Aids Research and Human Retroviruses, 29:A34–A34. MARY ANN LIEBERT, INC, 2013.Link to Item
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Wise, M., N. Hutnick, J. Pollara, D. Myles, A. Khan, S. Barnette, G. Ferrari, D. Montefiori, N. Sardesai, and D. Weiner. “Multiclade E-DNA Prime Enhances the Functional Antibody Response Induced by a Recombinant gp120 Boost in Non-human Primates.” In Aids Research and Human Retroviruses, 29:A38–A38. MARY ANN LIEBERT, INC, 2013.Link to Item
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Blasi, M., D. Negri, S. Santra, R. Parks, X. Shen, G. Tomaras, S. Permar, et al. “A Single Immunization with Integrase Defective Lentiviral Vector Expressing gp140 Induces Persistent and Functional Immune Response in Rhesus Monkeys.” In Aids Research and Human Retroviruses, 29:A161–A161. MARY ANN LIEBERT, INC, 2013.Link to Item
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Bonsignori, M., J. Pollara, M. A. Moody, T. B. Kepler, X. Chen, T. C. Gurley, D. M. Kozink, et al. “Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial preferentially use the VH1 gene family.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p78.Full Text
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Franchini, G., P. Pegu, S. Gordon, B. Keele, M. Doster, Y. Guan, G. Ferrari, et al. “Antibodies to the envelope protein protect macaques from SIVmac251 acquisition in an immunization regimen that mimics the RV-144 Thai trial.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o2.Full Text
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Hutnick, N. A., M. Karuppiah, J. Pollara, J. Yan, D. J. Myles, K. Broderick, M. Morrow, et al. “E-DNA IM or ID delivery prime enhances antibody and T cell responses following recombinant gp120 env boost.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-p364.Full Text
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Joachim, A., C. Nilsson, S. Aboud, E. F. Lyamuya, M. Robb, M. Marovich, C. Ochsenbauer, et al. “Antibody-mediated inhibition of HIV-1 elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o53.Full Text
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Pollara, J., M. Bonsignori, M. Moody, M. Alam, H. Liao, K. Hwang, J. Pickeral, et al. “Vaccine-induced ADCC-mediating antibodies target unique and overlapping envelope epitopes.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o39.Full Text
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Williams, W. B., K. Jones, A. Krambrink, D. Grove, P. Liu, N. L. Yates, M. A. Moody, et al. “Multiple antibody specificities (gp41, V1V2, and V3) elicited in the phase II multiclade (A, B, C) HIV-1 DNA prime, rAd5 boost vaccine trial.” In Retrovirology, Vol. 9. Springer Science and Business Media LLC, 2012. https://doi.org/10.1186/1742-4690-9-s2-o55.Full Text
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Ferrari, G., J. Cox, A. Garcia, W. Rountree, C. DeCastro, R. Louzao, B. Liebl, et al. “Development of CAVD/EQAPOL Long-Term PBMC Repository ('07-'10) @ DUMC; T-Cell Functionality as Measured by ELISpot and Flow Cytometry Is Maintained Ov.” In Aids Research and Human Retroviruses, 27:A55–A55. MARY ANN LIEBERT INC, 2011.Link to Item
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Fouda, G., N. Yates, J. Pollara, G. Overman, T. Mahlokozera, A. Wilks, H. Kang, et al. “HIV Neutralization in Breast Milk Mirrors that of Plasma and Is Mainly Mediated by IgG Antibodies.” In Aids Research and Human Retroviruses, 27:A72–A72. MARY ANN LIEBERT INC, 2011.Link to Item
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Franchini, G., M. Vaccari, B. Keele, M. Doster, Z. Ma, A. Hryniewicz, T. Morgan, et al. “Efficacy of HIV Vaccine Candidate in Macaques Dependent on the Dose of SIVmac251 Challenge Exposure: Immune Correlates of Vaccine Efficacy.” In Aids Research and Human Retroviruses, 27:A111–A111. MARY ANN LIEBERT INC, 2011.Link to Item
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Franchini, G., P. Pegu, M. Vaccari, S. Gordon, B. Keele, M. Doster, Y. Guan, et al. “Titered Mucosal Challenge of Rhesus Macaques with SIVmac251 Recapitulates HIV Vaccine Efficacy in Humans.” In Aids Research and Human Retroviruses, 27:A4–A4. MARY ANN LIEBERT INC, 2011.Link to Item
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Pollara, J., L. Morris, N. Meguid, J. Pickeral, J. Hoxie, J. Kappes, C. Ochsenbauer, et al. “Ontogeny, Breadth, and Specificity of Circulating ADCC-Mediating Antibodies in HIV-1 Infected Individuals.” In Aids Research and Human Retroviruses, 27:A66–67. MARY ANN LIEBERT INC, 2011.Link to Item
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Ferrari, G., J. Pollara, D. Kozink, T. Harms, M. Drinker, S. Freel, M. A. Moody, et al. “Mapping of ADCC Activity: The A32 Conformational C1 Epitope is a Dominant Target for ADCC Antibodies in Chronically HIV-1 Infected Subjects.” In Aids Research and Human Retroviruses, 27:A66–A66. MARY ANN LIEBERT INC, 2011.Link to Item
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Freel, S. A., R. A. Picking, G. Ferrari, C. Ochsenbauer, J. C. Kappes, J. Kirchherr, K. J. Weinhold, et al. “Ontogeny of CD8+T Cells in Acute HIV-1 that Inhibit Autologous and Heterologous Transmitted/Founder (T/F) Viruses.” In Aids Research and Human Retroviruses, 27:A13–A13. MARY ANN LIEBERT INC, 2011.Link to Item
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Ferrari, G., B. Korber, E. Turnbull, M. K. Liu, N. Goonetilleke, J. Salazar, M. Betts, et al. “High magnitude and multifunctionality epitope-specific CD8+T-cell responses are associated are associated with selection of escape mutants in acute HIV infection.” In Aids Research and Human Retroviruses, 26:A5–6. MARY ANN LIEBERT INC, 2010.Link to Item
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Pollara, J., G. Landucci, C. Trac, C. White, N. Yates, J. Kappes, C. Ochsenbauer, et al. “Early Appearance of ADCC- and ADCVI-mediating Antibody Responses Against Autologous HIV-1 Transmitted/Founder Virus.” In Aids Research and Human Retroviruses, 26:A12–A12. MARY ANN LIEBERT INC, 2010.Link to Item
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Pollara, J., L. Hart, J. Hoxie, J. Kappes, C. Ochsenbauer, L. Morris, K. Soderberg, et al. “High titers of cross-clade ADCC-mediating antibodies are detectable in plasma samples collected from individuals with broadly neutralizing antibodies.” In Aids Research and Human Retroviruses, 26:A20–21. MARY ANN LIEBERT INC, 2010.Link to Item
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Yates, N., X. Shen, P. Liu, S. Barnett, P. Spearman, S. Lu, G. Ferrari, et al. “Vaccine-Elicited IgG Subclasses and Functional Antibodies.” In Aids Research and Human Retroviruses, 26:A157–A157. MARY ANN LIEBERT INC, 2010.Link to Item
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Cristillo, A. D., G. Ferrari, L. Hudacik, D. Thompson, B. Bowen, B. Lewis, L. Galmin, et al. “P11-21. Induction of persistent mucosal humoral and cellular responses following immunization of mice with HIV-1 envelope protein in inulin-derived adjuvants.” In Retrovirology, 6:P166–P166, 2009. https://doi.org/10.1186/1742-4690-6-S3-P166.Full Text
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Ferrari, G., A. Garcia-Louzao, J. Cox, A. Sambor, P. D’Souza, C. Gray, M. Jaimes, et al. “Establishing PBMC Repository for T Cell Assays Optimization and Proficiency Testing in CTC-VIMC Laboratories.” In Aids Research and Human Retroviruses, 24:127–28. MARY ANN LIEBERT INC, 2008.Link to Item
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Ferrari, G., M. Liu, C. Marking, N. Goonetilleke, M. Betts, C. Gray, B. Haynes, A. McMichael, and K. Weinhold. “Lack of Highly Poly-Functional Epitope-Specific CD8+Memory T Cell Responses during Spontaneous Control of Viremia.” In Aids Research and Human Retroviruses, 24:20–20. MARY ANN LIEBERT INC, 2008.Link to Item
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Liu, M. K., G. Ferrari, J. Salazar, B. Keele, R. L. Tanner, E. Turnbull, M. Mlotshwa, et al. “T Cell Escape in Subjects with Acute HIV-1 Infection.” In Aids Research and Human Retroviruses, 24:6–7. MARY ANN LIEBERT INC, 2008.Link to Item
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Sichangi, M. W., J. Bartlett, G. Ferrari, J. Crump, A. Muisyo, J. Puleo, T. Moody, B. Haynes, and J. Shao. “Detection of Cross-Clade T- and B-Cell-Mediated Immune Responses among HIV-1 Infected Individuals in Northern Tanzania.” In Aids Research and Human Retroviruses, 24:92–92. MARY ANN LIEBERT INC, 2008.Link to Item
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Lathey, Janet, Neal Oden, Scott Gregory, Josephine Cox, Guido Ferrari, Susan Zimmermann, Richard Koup, M. Patricia D’Souza, and Isaac Rodriguez-Chavez. “Sa.133. ELISpot Proficiency Testing for International Laboratories Participating in HIV Vaccine Trials.” In Clinical Immunology, 119:S152–S152. Elsevier BV, 2006. https://doi.org/10.1016/j.clim.2006.04.365.Full Text
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Sempowski, G. D., C. Hicks, L. Edwards, G. Ferrari, J. Eron, and B. F. Haynes. “Naive T cells are maintained in the periphery during acute HIV infection.” In Faseb Journal, 16:A297–A297. FEDERATION AMER SOC EXP BIOL, 2002.Link to Item
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Demarest, J. F., S. B. Jones, G. Ferrari, C. J. Johnson, M. Greenberg, T. O. O’Brien, W. Blattner, et al. “Natural history of HIV-specific CTL activity during acute HIV infection: envelope CTL impact subsequent plasma viremia.” In Faseb Journal, 13:A294–A294. WILEY, 1999.Link to Item
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Weinhold, K. J., W. Humphrey, K. Corr, J. Johnson, M. West, C. Wiggins, S. Jones, J. Ottinger, M. Blanks, and G. Ferrari. “Cellular immune responses to candidate AIDS vaccines.” In 11e Colloque Des Cent Gardes, edited by M. Girard and B. Dodet, 167–75. EDITIONS SCIENTIFIQUES ET MEDICALES ELSEVIER, 1998.Link to Item
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Stranford, S., J. Skurnick, D. Louria, D. Osmond, S. Y. Chang, J. Sninsky, G. Ferrari, K. Weinhold, C. Lindquist, and J. Levy. “The CD8+ cell non-cytotoxic, anti-HIV response is associated with protection in HIV-exposed, uninfected individuals.” In Faseb Journal, 12:A295, 1998.
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Laughlin, M. J., J. Kurtzberg, K. Weinhold, G. Ferrari, A. Pilgrim, C. Gelber, S. Nair, et al. “Generation of T lymphocyte clones specific for acute lymphoblastic leukemia (ALL) via dendritic cell (DC) presentation.” In Blood, 88:1487–1487. W B SAUNDERS CO, 1996.Link to Item
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FERRARI, G., C. PLACE, J. BARTLETT, D. MOODY, J. TARTAGLIA, E. PAOLETTI, and K. WEINHOLD. “ANTIGEN-SPECIFIC ACTIVATION/EXPANSION OF HUMAN ANTI-HIV CTL USING RECOMBINANT ALVAC (CANARYPOX)-BASED VECTORS.” In Journal of Cellular Biochemistry, 219–219. WILEY-LISS, 1995.Link to Item
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FERRARI, G., K. KING, M. PACKARD, J. A. BARTLETT, J. TARTAGLIA, J. TOSO, and K. J. WEINHOLD. “THE EFFECT OF INTERLEUKIN-7 ON FUNCTIONAL AND PHENOTYPIC PROPERTIES OF ANTIGEN-DRIVEN CTL.” In Journal of Cellular Biochemistry, 354–354. WILEY-LISS, 1994.Link to Item
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WEINHOLD, K. J., K. T. RATHBUN, C. A. PLACE, G. FERRARI, and D. P. BOLOGNESI. “CYTOTOXIC T-LYMPHOCYTE REACTIVITIES AMONG HIV-1 VACCINE RECIPIENTS IN THE AIDS VACCINE EVALUATION NETWORK.” In Aids Research and Human Retroviruses, 10:S89–S89. MARY ANN LIEBERT INC PUBL, 1994.Link to Item
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FERRARI, G., M. V. PACKARD, J. A. BARTLETT, and K. J. WEINHOLD. “TH1 AND TH2 CD4 SUBSET RESPONSES IN HIV-1 INFECTED INDIVIDUALS AT VARIOUS STAGES OF DISEASE.” In Journal of Cellular Biochemistry, 78–78. WILEY-LISS, 1993.Link to Item
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WEINHOLD, K. J., G. FERRARI, and L. O. ARTHUR. “COMPARISON OF CELLULAR ANTIVIRAL CYTOTOXICITIES PRESENT IN HIV-1 INFECTED HUMANS AND CHIMPANZEES.” In Aids Research and Human Retroviruses, 8:938–938. MARY ANN LIEBERT INC PUBL, 1992.Link to Item
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TAGLIAFERRO, L., M. CORBELLI, P. GRIMA, S. REINA, F. LILLO, E. BOERI, G. FERRARI, and O. E. VARNIER. “HTLV REACTIVITY IN NORMAL POPULATION OF SOUTHERN APULIA (ITALY).” In Aids Research and Human Retroviruses, 6:141–141. MARY ANN LIEBERT INC PUBL, 1990.Link to Item
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- Teaching & Mentoring
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Recent Courses
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Advising & Mentoring
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I have been involved in teaching and training new researchers in several capacities. Since 2001, as part of consulting work for the World Health Organization and United Nation AIDS program (WHO/UNAIDS), I have organized and taught in 8 international ELISpot and Flow Cytometry workshops in South America (1), Asia (1), and Africa (6) to developing international sites that can perform vaccine clinical trials. In this capacity, I have taught more than 150 young investigators around the world. In 2002 and 2003, I taught the HIV-1 Vaccine development lecture for the IMM291 Comprehensive Immunology Course in the Duke Department of Immunology. Starting in 2007, I have also been awarded two R13 grants from the NIH to organize a series of International Symposia in South Africa that fosters interactions between young African scientists selected among those working in the HIV, TB, and malaria fields and senior international faculty. We have currently provided career development opportunity to more than 52 young investigators and facilitated the forum for a network of young investigators within the African continents.
Moreover, I was one of the Co-Investigators for the MEPI project directed by Dr. J. Bartlett that collaborates with the Faculty at the Kilimanjaro Christian Medical College to develop a new curriculum of study for the students and to improve the teaching curriculum for the faculty members within the Basic Science fields. I consider this teaching as an integral part of my mandate as a scientist interested in Global Health to promote the education and interaction of the generation of young investigators, with particular focus on the African community.Mentoring has also been an important aspect of my career. Since joining the faculty in 2001, I have mentored 6 undergraduate students during their junior and senior year to perform independent research projects in my laboratory. Of them, 2 have already achieved their medical degree (Dr. Kolappa from John Hopkins University in 2009, Dr. Chaudhry from Brown University in 2009). Ms Hofmair is completing her medical degree at Duke University while achieving a MBA in medical science and a MPH in women health. Mr. Laithi graduated in 2010 and applying to Medical School for 2012. Ms. DiMarco who has recently graduated in May 2012 and has been accepted in Medical School at he University of Virginia. Mr. Hickey has completed his junior year project and we rejoin the lab after a summer internship at the University of KwaZulu-Natal (Durban, South Africa).In 2006, Marc Frahm joined my laboratory as graduate students for the Molecular Genetics and Microbiology Department. He has currently achieved the necessary requirements to defend his thesis and will graduate in August 2012.
I have been a faculty mentor for the AIDS Training Grant starting in 2005 (Department of Medicine, T32). I have directly mentored two post-doctoral fellows Dr. Jie Yu (2007-2010) and Dr, Justin Pollara (2010-currently). Dr Yu is currently a Research Associate at Duke University with Dr. Chen after completing 3 years of training in my laboratory. Dr. Pollara is still in my laboratory and has already published 19 manuscripts, of which four as first author, and has five more manuscripts in preparation, two of those as first author. Dr. Pollara has been awarded a CHAVI Young Investigator for his work on fundamental insights into the HIV-1 ADCC antibody response. My career goals since joining the Duke faculty in September 2001 have been to make an impact on young investigators through basic research and teaching and mentoring undergraduate, graduate and medical students, and postdoctoral fellows at Duke University.
Available to mentor:
- PhD
- Post-Doc
- Undergraduate
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- Scholarly, Clinical, & Service Activities
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Presentations & Appearances
- Optimized detection of ADCC activities and cross-protocol analyses . HIV Vaccine Triall Network Full Group Meeting. HIV Vaccine Trial Network. October 25, 2017 2017
- Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection. 19th International Meeting of the Institute of Human Virology. Institute of Human Virology. October 23, 2017 2017
- Antibody binding to HIV-1 infected cells as mechanism to protection from and treatment of HIV infection. HIV Cure Seminar. University of North Carolina-Chapel Hill. March 23, 2017 2017
- Antibody Recognition of HIV-1 Envelope for Prevention and Treatment. Research Lecture Series. University of Massachusetts Medical School. March 22, 2017 2017
- Learning from Antibody Dependent Cellular Cytotoxicity to prevent and treat HIV-1 infection. University of Drexel. January 23, 2017 - January 23, 2017 2017
- DART® molecules for treatment of HIV-1 infection. IBC's 26th Annual Antibody Engineering & Therapeutics. IBC Life Sciences. December 14, 2016 2016
- Understanding ADCC responses for vaccine and therapeutic designs. University of Cape Town. December 1, 2016 2016
- Cross-protocol analyses of ADCC responses. HIV Vaccine Trial Network Full Group Meeting. HVTN. November 18, 2016 2016
- Targeting of HIV-1 life cycle by polyclonal and monoclonal ADCC-mediating antibodies. Workshop on Beyond neutralizing Ab responses. AIDS Research for Prevention. October 21, 2016 2016
- A tango in immunology: when Antibodies Date Cytotoxic Cells. Spring Seminar Series. University of Wyoming. January 28, 2016 2016
- Antibody-dependent cellular cytotoxicity in HIV protection . The 6th INTEREST Workshop. May 14, 2013 - May 17, 2013 2013
- Flow Cytometry in Acute HIV Infection Research. The 4th INTEREST Workshop. May 11, 2011 - May 12, 2011 2011
- Early appearance of ADCC- and ADCVI-mediating antibody responses against autologous HIV-1 transmitted/founder virus. The AIDS Vaccine 2010 Conference. September 28, 2010 - October 1, 2010 2010
- High magnitude and multifunctionality epitope-specific CD8+ T-cellresponses are associated with selection of escape mutants in acute HIV infection. The AIDS Vaccine 2010 Conference. September 28, 2010 - October 1, 2010 2010
- Flow Cytometry in HIV Research. The 3rd INTEREST Workshop. May 26, 2009 - May 29, 2009 2009
- Acceptance criteria for cellular immune assay performance. 8th Annual Meeting of the Cancer Vaccine Consortium. March 25, 2009 - March 28, 2009 2009
- Lack of highly poly-functional epitope-specific CD8+ memory T cell responses during spontaneous control of viremia. AIDS Vaccine 2008 Conference. October 13, 2008 - October 16, 2008 2008
- Profiles of memory and functional T cell responses in the early stages of subtype B HIV-1 acute infection. The 2nd Uganda AIDS Conference. September 25, 2008 - September 26, 2008 2008
- Impact of Assay Validation and GCLP Compliance on Vaccine Evaluation. The 1st Uganda AIDS Conference. December 7, 2006 - December 8, 2006 2006
- Lack of protection from HIV-1 infection by Gag-specific CD4+ and CD8+ T cell responses induced by a recombinant HIV canarypox vaccine vector (vCP205). AIDS Vaccine 2004. August 30, 2004 - September 1, 2004 2004
- Function and phenotype of vaccine-induced Gag-specific T cell responses before and after infection. 4th International Symposium on “Immunological Correlates of Protection from HIV Infection and Disease. August 27, 2004 - August 29, 2004 2004
- Lack of Protection from HIV-1 Infection by a HLA-B27-restricted anti-p24 gag CD8+ T cell response induced by a recombinant HIV canarypox vaccine vector. XV International AIDS Conference. International AIDS Society. July 11, 2003 - July 16, 2003 2003
- CTL Responses In Individuals Participating in HIV Vaccine Trials. 5th Congress of the Federation of African Immunological Societies. FAIS. April 27, 2003 - May 2, 2003 2003
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