Guido Ferrari | Scholars@Duke

Guido Ferrari
Associate Professor of Surgery

The activities of the Ferrari Laboratory are based on both independent basic research and immune monitoring studies. The research revolves around three main areas of interest: class I-mediated cytotoxic CD8+ T cell responses, antibody-dependent cellular cytotoxicity (ADCC), gene expression in NK and T cellular subsets upon infection with HIV-1. With continuous funding over the last 11 years from the NIH and Bill & Melinda Gates Foundation along with many other productive collaborations within and outside of Duke, the Ferrari Lab has expanded its focus of research to include the ontogeny of HIV-1 specific immune responses that work by eliminating HIV-1 infected cells and how these can be induced by AIDS vaccine candidates.

Office Hours

Monday-Friday 08:00-18:00
Saturday and Sunday upon request

Current Appointments & Affiliations

Associate Professor of Surgery, Surgery, Surgical Sciences, Surgery 2013
Associate Research Professor in Molecular Genetics and Microbiology, Molecular Genetics and Microbiology, Basic Science Departments 2014
Member of the Duke Human Vaccine Institute, Duke Human Vaccine Institute, Institutes and Centers 2009
Affiliate, Duke Global Health Institute, Duke Global Health Institute, University Institutes and Centers 2009

Contact Information

115 Surg Oncol Res Fac, Durham, NC 27710
Box 2926 Med Ctr, Durham, NC 27710
gflmp@duke.edu (919) 684-2862

Background
Education, Training, & Certifications
- M.D., University of Genoa (Italy) 1985
Duke Appointment History
- Assistant Professor of Surgery, Surgery, Surgical Sciences, Surgery 2006 - 2013
- Assistant Research Professor in Surgery, Surgery, Surgical Sciences, Surgery 2001 - 2006
Academic Positions Outside Duke
- Adjunct Visiting Professor, University of Cape Town. 2012 - 2018
Recognition
In the News
- NOV 27, 2018
  
  Duke Faculty Plentiful On ‘Highly Cited’ List
Expertise
Subject Headings
Global Scholarship
- Research
  - South Africa (Country)
Research
Selected Grants
- EQAPOL - Years 2017 to 2024 - BASE awarded by National Institutes of Health 2017 - 2024
- Targeting Apoptosis and Immune Control of Epstein-Barr Virus Infected Tonsillar B Cells awarded by National Institutes of Health 2016 - 2021
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2020
- Interdisciplinary Research Training Program in AIDS awarded by National Institutes of Health 2010 - 2020
- 13th International Conference on HIV Treatment, Pathogenesis, and Prevention Research (Interest) awarded by National Institutes of Health 2019 - 2020
- Nonhuman Primate Option 1 awarded by National Institutes of Health 2018 - 2020
- Project 2: Synthetic DNA & Novel Env Vaccine for HIV 2015 - 2020
- Infectious Diseases in Africa: Immune Escape and HIV Vaccines awarded by National Institutes of Health 2009 - 2020
- Eqapol Opt 1 -2018-2019 awarded by National Institutes of Health 2017 - 2019
- CARE Focus 1: Latency Biomarker Project awarded by University of North Carolina - Chapel Hill 2018 - 2019
- CARE Focus 2: Clearance of HIV Antigen-Positive Cells awarded by University of North Carolina - Chapel Hill 2016 - 2019
- Dual-Affinity Re-Targeting Proteins for Cure of Newborn Infant HIV-1 Infection awarded by National Institutes of Health 2016 - 2019
- Creation of a bnAbnectin 2017 - 2019
- IGM Proposal 2016 - 2019
- 2018 INTEREST Conference awarded by National Institutes of Health 2018 - 2019
- Project 2: Synthetic DNA & Novel Env Vaccine for HIV 2015 - 2019
- HIV Vaccine Trials Network: LC P5 PF 2015 - 2018
- HVTN - A004 2015 - 2018
- Evaluation of the host immune response and viral molecular phenotype in lung transplant recipients with PTLD awarded by Mount Sinai School of Medicine 2017 - 2018
- Impact of Fc N-glycan structure on HIV-specific antibody functions awarded by University of Wyoming 2016 - 2018
- CARE Duke-UNC Latency Biomarker Supplement Year 2 awarded by University of North Carolina - Chapel Hill 2016 - 2018
- 2017 INTEREST Conference awarded by National Institutes of Health 2017 - 2018
- Nonhuman Primate Core-Option 6 awarded by National Institutes of Health 2012 - 2018
- EQAPOL - Option 6 - 2016 to 2017 - ELISPOT awarded by National Institutes of Health 2010 - 2017
- EQAPOL Option 5 awarded by National Institutes of Health 2010 - 2017
- Focus 1: Detection of HIV Antigen-Positive Cells awarded by University of North Carolina - Chapel Hill 2016 - 2017
- Invitro Function of DART Molecules (Base) 2016 - 2017
- Infant immune correlates of perinatal mother to child transmission of HIV awarded by National Institutes of Health 2015 - 2017
- Intervening with Latent HIV-1 Infection using Gnidimacrin awarded by National Institutes of Health 2014 - 2017
- 10th INTEREST Workshop on HIV awarded by National Institutes of Health 2016 - 2017
- HIV Vaccine Trials Network: LC P5 PF 2014 - 2015
- LC: HIV Vaccine Trials Network: Phase 1 PF 2014 - 2015
- Vaccine-induced HIV antibody responses in infants awarded by National Institutes of Health 2012 - 2015
- HIV-1 Gene Suppression by CD8+ T Cells awarded by National Institutes of Health 2002 - 2015
- AIDS International Training and Research Program awarded by National Institutes of Health 2003 - 2014
- Poly-functional analyses of vaccine-induced T cell responses awarded by National Institutes of Health 2001 - 2012
- Correlates of Vaccine Protection Workshop awarded by National Institutes of Health 2010 - 2011
- International Clinical Trials Unit awarded by National Institutes of Health 2004 - 2009
- Infectious Diseases in Africa: Measurement of Immune Responses awarded by National Institutes of Health 2007 - 2008
- Central Laboratory for the HIV Vaccines Trial Network awarded by National Institutes of Health 2000 - 2006
- NCRR FACSAria Cell Sorter 2004 - 2006
- Anti-Hiv Ctl And Hiv Suppressive Cd8 Cells awarded by National Institutes of Health 1990 - 2000
- Anti-Hiv Ctl And Hiv-Suppresive Cd8+ Cells awarded by National Institutes of Health 1996 - 1999
- Anti-Hiv Ctl And Hiv Suppresive Cd8+ Cells awarded by National Institutes of Health 1995 - 1999
- Antihiv Ctl And Hiv Suppressive Cd8 Cells awarded by National Institutes of Health 1990 - 1999
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Pollara, Justin, Dorothy I. Jones, Tori Huffman, R Whitney Edwards, Maria Dennis, Shuk Hang Li, Shalini Jha, et al. “Bridging Vaccine-Induced HIV-1 Neutralizing and Effector Antibody Responses in Rabbit and Rhesus Macaque Animal Models..” J Virol 93, no. 10 (May 15, 2019). https://doi.org/10.1128/JVI.02119-18.
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  - Spearman, Paul, Georgia D. Tomaras, David C. Montefiori, Ying Huang, Marnie L. Elizaga, Guido Ferrari, S Munir Alam, et al. “Rapid Boosting of HIV-1 Neutralizing Antibody Responses in Humans Following a Prolonged Immunologic Rest Period..” J Infect Dis 219, no. 11 (May 5, 2019): 1755–65. https://doi.org/10.1093/infdis/jiz008.
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  - Pittala, Srivamshi, Kenneth Bagley, Jennifer A. Schwartz, Eric P. Brown, Joshua A. Weiner, Ilia J. Prado, Wenlei Zhang, et al. “Antibody Fab-Fc properties outperform titer in predictive models of SIV vaccine-induced protection..” Mol Syst Biol 15, no. 5 (May 2, 2019). https://doi.org/10.15252/msb.20188747.
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  - Pardi, Norbert, Celia C. LaBranche, Guido Ferrari, Derek W. Cain, István Tombácz, Robert J. Parks, Hiromi Muramatsu, et al. “Characterization of HIV-1 Nucleoside-Modified mRNA Vaccines in Rabbits and Rhesus Macaques..” Mol Ther Nucleic Acids 15 (April 15, 2019): 36–47. https://doi.org/10.1016/j.omtn.2019.03.003.
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  - Curtis, Alan D., Korey A. Walter, Rafiq Nabi, Kara Jensen, Aanini Dwivedi, Justin Pollara, Guido Ferrari, et al. “Oral Coadministration of an Intramuscular DNA/Modified Vaccinia Ankara Vaccine for Simian Immunodeficiency Virus Is Associated with Better Control of Infection in Orally Exposed Infant Macaques..” Aids Research and Human Retroviruses 35, no. 3 (March 2019): 310–25. https://doi.org/10.1089/aid.2018.0180.
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  - Dennis, Maria, Joshua Eudailey, Justin Pollara, Arthur S. McMillan, Kenneth D. Cronin, Pooja T. Saha, Alan D. Curtis, et al. “Coadministration of CH31 Broadly Neutralizing Antibody Does Not Affect Development of Vaccine-Induced Anti-HIV-1 Envelope Antibody Responses in Infant Rhesus Macaques..” J Virol 93, no. 5 (March 1, 2019). https://doi.org/10.1128/JVI.01783-18.
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  - Kibler, Karen V., Benedikt Asbach, Beatriz Perdiguero, Juan García-Arriaza, Nicole L. Yates, Robert Parks, Sherry Stanfield-Oakley, et al. “Replication-Competent NYVAC-KC Yields Improved Immunogenicity to HIV-1 Antigens in Rhesus Macaques Compared to Nonreplicating NYVAC..” J Virol 93, no. 3 (February 1, 2019). https://doi.org/10.1128/JVI.01513-18.
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  - Pantaleo, Giuseppe, Holly Janes, Shelly Karuna, Shannon Grant, Laissa Ouedraogo, Mary Allen, Georgia D. Tomaras, et al. “Co-Administration of HIV Env Protein with DNA and/or NYVAC Vaccines in Humans Results in Earlier and Potent Generation of Anti-Env Antibody Responses,” January 25, 2019.
  - Lewis, George K., Margaret E. Ackerman, Gabriella Scarlatti, Christiane Moog, Marjorie Robert-Guroff, Stephen J. Kent, Julie Overbaugh, R Keith Reeves, Guido Ferrari, and Bargavi Thyagarajan. “Knowns and Unknowns of Assaying Antibody-Dependent Cell-Mediated Cytotoxicity Against HIV-1..” Front Immunol 10 (2019). https://doi.org/10.3389/fimmu.2019.01025.
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  - Manickam, Cordelia, Spandan V. Shah, Junsuke Nohara, Guido Ferrari, and R Keith Reeves. “Monkeying Around: Using Non-human Primate Models to Study NK Cell Biology in HIV Infections..” Front Immunol 10 (2019). https://doi.org/10.3389/fimmu.2019.01124.
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  - Eeden, Charmaine van, Constantinos Kurt Wibmer, Cathrine Scheepers, Simone I. Richardson, Molati Nonyane, Bronwen Lambson, Nonhlanhla N. Mkhize, et al. “V2-Directed Vaccine-like Antibodies from HIV-1 Infection Identify an Additional K169-Binding Light Chain Motif with Broad ADCC Activity..” Cell Rep 25, no. 11 (December 11, 2018): 3123-3135.e6. https://doi.org/10.1016/j.celrep.2018.11.058.
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  - Himes, Jonathon E., Ria Goswami, Riley J. Mangan, Amit Kumar, Thomas L. Jeffries, Joshua A. Eudailey, Holly Heimsath, et al. “Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys..” Mucosal Immunol 11, no. 6 (November 2018): 1716–26. https://doi.org/10.1038/s41385-018-0067-7.
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  - Phillips, Bonnie, Koen K. A. Van Rompay, Jennifer Rodriguez-Nieves, Clarisse Lorin, Marguerite Koutsoukos, Mark Tomai, Christopher B. Fox, et al. “Adjuvant-Dependent Enhancement of HIV Env-Specific Antibody Responses in Infant Rhesus Macaques..” J Virol 92, no. 20 (October 15, 2018). https://doi.org/10.1128/JVI.01051-18.
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  - Bradley, Todd, Dimitra Peppa, Isabela Pedroza-Pacheco, Dapeng Li, Derek W. Cain, Ricardo Henao, Vaishnavi Venkat, et al. “RAB11FIP5 Expression and Altered Natural Killer Cell Function Are Associated with Induction of HIV Broadly Neutralizing Antibody Responses..” Cell 175, no. 2 (October 4, 2018): 387-399.e17. https://doi.org/10.1016/j.cell.2018.08.064.
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  - Bradley, Todd, Guido Ferrari, Barton F. Haynes, David M. Margolis, and Edward P. Browne. “Single-Cell Analysis of Quiescent HIV Infection Reveals Host Transcriptional Profiles that Regulate Proviral Latency..” Cell Reports 25, no. 1 (October 2018): 107-117.e3. https://doi.org/10.1016/j.celrep.2018.09.020.
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  - Singh, Shakti, Eric G. Ramírez-Salazar, Rami Doueiri, Antonio Valentin, Margherita Rosati, Xintao Hu, Brandon F. Keele, et al. “Control of Heterologous Simian Immunodeficiency Virus SIVsmE660 Infection by DNA and Protein Coimmunization Regimens Combined with Different Toll-Like-Receptor-4-Based Adjuvants in Macaques..” J Virol 92, no. 15 (August 1, 2018). https://doi.org/10.1128/JVI.00281-18.
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  - Naggie, Susanna, Marzena Swiderska-Syn, Steve Choi, Sam Lusk, Audrey Lan, Guido Ferrari, Wing-Kin Syn, Cynthia D. Guy, and Anna Mae Diehl. “Markers of Tissue Repair and Cellular Aging Are Increased in the Liver Tissue of Patients With HIV Infection Regardless of Presence of HCV Coinfection..” Open Forum Infect Dis 5, no. 7 (July 2018). https://doi.org/10.1093/ofid/ofy138.
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  - Garrido, Carolina, Maria Abad-Fernandez, Marina Tuyishime, Justin J. Pollara, Guido Ferrari, Natalia Soriano-Sarabia, and David M. Margolis. “Interleukin-15-Stimulated Natural Killer Cells Clear HIV-1-Infected Cells following Latency Reversal Ex Vivo..” J Virol 92, no. 12 (June 15, 2018). https://doi.org/10.1128/JVI.00235-18.
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  - Ferrari, Guido. “Tandem bispecific broadly neutralizing antibody - a novel approach to HIV-1 treatment..” J Clin Invest 128, no. 6 (June 1, 2018): 2189–91. https://doi.org/10.1172/JCI121078.
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  - Saunders, Kevin O., Sampa Santra, Robert Parks, Nicole L. Yates, Laura L. Sutherland, Richard M. Scearce, Harikrishnan Balachandran, et al. “Immunogenicity of NYVAC Prime-Protein Boost Human Immunodeficiency Virus Type 1 Envelope Vaccination and Simian-Human Immunodeficiency Virus Challenge of Nonhuman Primates..” J Virol 92, no. 8 (April 15, 2018). https://doi.org/10.1128/JVI.02035-17.
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  - Pollara, Justin, Chiara Orlandi, Charles Beck, R Whitney Edwards, Yi Hu, Shuying Liu, Shixia Wang, et al. “Application of area scaling analysis to identify natural killer cell and monocyte involvement in the GranToxiLux antibody dependent cell-mediated cytotoxicity assay..” Cytometry A 93, no. 4 (April 2018): 436–47. https://doi.org/10.1002/cyto.a.23348.
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  - Wills, Saintedym, Kwan-Ki Hwang, Pinghuang Liu, S Moses Dennison, Matthew Zirui Tay, Xiaoying Shen, Justin Pollara, et al. “HIV-1-Specific IgA Monoclonal Antibodies from an HIV-1 Vaccinee Mediate Galactosylceramide Blocking and Phagocytosis..” J Virol 92, no. 7 (April 1, 2018). https://doi.org/10.1128/JVI.01552-17.
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  - Fong, Youyi, Xiaoying Shen, Vicki C. Ashley, Aaron Deal, Kelly E. Seaton, Chenchen Yu, Shannon P. Grant, et al. “Modification of the Association Between T-Cell Immune Responses and Human Immunodeficiency Virus Type 1 Infection Risk by Vaccine-Induced Antibody Responses in the HVTN 505 Trial..” J Infect Dis 217, no. 8 (March 28, 2018): 1280–88. https://doi.org/10.1093/infdis/jiy008.
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  - Jones, Andrew T., Venkateswarlu Chamcha, Sannula Kesavardhana, Xiaoying Shen, David Beaumont, Raksha Das, Linda S. Wyatt, et al. “A Trimeric HIV-1 Envelope gp120 Immunogen Induces Potent and Broad Anti-V1V2 Loop Antibodies against HIV-1 in Rabbits and Rhesus Macaques..” J Virol 92, no. 5 (March 1, 2018). https://doi.org/10.1128/JVI.01796-17.
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  - Viegas, Edna Omar, Nelson Tembe, Charlotta Nilsson, Bindiya Meggi, Cremildo Maueia, Orvalho Augusto, Richard Stout, et al. “Intradermal HIV-1 DNA Immunization Using Needle-Free Zetajet Injection Followed by HIV-Modified Vaccinia Virus Ankara Vaccination Is Safe and Immunogenic in Mozambican Young Adults: A Phase I Randomized Controlled Trial..” Aids Res Hum Retroviruses 34, no. 2 (February 2018): 193–205. https://doi.org/10.1089/AID.2017.0121.
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  - Blasi, Maria, Donatella Negri, Celia LaBranche, S Munir Alam, Erich J. Baker, Elizabeth C. Brunner, Morgan A. Gladden, et al. “IDLV-HIV-1 Env vaccination in non-human primates induces affinity maturation of antigen-specific memory B cells..” Commun Biol 1 (2018). https://doi.org/10.1038/s42003-018-0131-6.
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  - Eudailey, Joshua A., Maria L. Dennis, Morgan E. Parker, Bonnie L. Phillips, Tori N. Huffman, Camden P. Bay, Michael G. Hudgens, et al. “Maternal HIV-1 Env Vaccination for Systemic and Breast Milk Immunity To Prevent Oral SHIV Acquisition in Infant Macaques..” Msphere 3, no. 1 (January 2018). https://doi.org/10.1128/mSphere.00505-17.
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  - Shen, Xiaoying, Rahul Basu, Sheetal Sawant, David Beaumont, Sue Fen Kwa, Celia LaBranche, Kelly E. Seaton, et al. “HIV-1 gp120 and Modified Vaccinia Virus Ankara (MVA) gp140 Boost Immunogens Increase Immunogenicity of a DNA/MVA HIV-1 Vaccine..” J Virol 91, no. 24 (December 15, 2017). https://doi.org/10.1128/JVI.01077-17.
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  - Francica, Joseph R., Daniel E. Zak, Caitlyn Linde, Emilio Siena, Carrie Johnson, Michal Juraska, Nicole L. Yates, et al. “Innate transcriptional effects by adjuvants on the magnitude, quality, and durability of HIV envelope responses in NHPs..” Blood Adv 1, no. 25 (November 28, 2017): 2329–42. https://doi.org/10.1182/bloodadvances.2017011411.
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  - Mayer, Kenneth H., Kelly E. Seaton, Yunda Huang, Nicole Grunenberg, Abby Isaacs, Mary Allen, Julie E. Ledgerwood, et al. “Safety, pharmacokinetics, and immunological activities of multiple intravenous or subcutaneous doses of an anti-HIV monoclonal antibody, VRC01, administered to HIV-uninfected adults: Results of a phase 1 randomized trial..” Plos Med 14, no. 11 (November 2017). https://doi.org/10.1371/journal.pmed.1002435.
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  - Liu, Donglai, Chu Wang, Bhavna Hora, Tao Zuo, Nilu Goonetilleke, Michael K. P. Liu, Mark Berrong, et al. “A strongly selected mutation in the HIV-1 genome is independent of T cell responses and neutralizing antibodies..” Retrovirology 14, no. 1 (October 10, 2017). https://doi.org/10.1186/s12977-017-0371-4.
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  - Bogers, Willy M. J. M., Susan W. Barnett, Herman Oostermeijer, Ivonne G. Nieuwenhuis, Niels Beenhakker, Daniella Mortier, Petra Mooij, et al. “Increased, Durable B-Cell and ADCC Responses Associated with T-Helper Cell Responses to HIV-1 Envelope in Macaques Vaccinated with gp140 Occluded at the CD4 Receptor Binding Site..” J Virol 91, no. 19 (October 1, 2017). https://doi.org/10.1128/JVI.00811-17.
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  - Phillips, Bonnie, Genevieve G. Fouda, Josh Eudailey, Justin Pollara, Alan D. Curtis, Erika Kunz, Maria Dennis, et al. “Impact of Poxvirus Vector Priming, Protein Coadministration, and Vaccine Intervals on HIV gp120 Vaccine-Elicited Antibody Magnitude and Function in Infant Macaques..” Clin Vaccine Immunol 24, no. 10 (October 2017). https://doi.org/10.1128/CVI.00231-17.
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  - Shen, Xiaoying, Willy M. Bogers, Nicole L. Yates, Guido Ferrari, Antu K. Dey, William T. Williams, Frederick H. Jaeger, et al. “Cross-Linking of a CD4-Mimetic Miniprotein with HIV-1 Env gp140 Alters Kinetics and Specificities of Antibody Responses against HIV-1 Env in Macaques..” J Virol 91, no. 19 (October 1, 2017). https://doi.org/10.1128/JVI.00401-17.
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  - Joachim, Agricola, Patricia J. Munseri, Charlotta Nilsson, Muhammad Bakari, Said Aboud, Eligius F. Lyamuya, Teghesti Tecleab, et al. “Three-Year Durability of Immune Responses Induced by HIV-DNA and HIV-Modified Vaccinia Virus Ankara and Effect of a Late HIV-Modified Vaccinia Virus Ankara Boost in Tanzanian Volunteers..” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 880–88. https://doi.org/10.1089/AID.2016.0251.
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  - Lewis, George K., Marzena Pazgier, David T. Evans, Guido Ferrari, Stylianos Bournazos, Matthew S. Parsons, Nicole F. Bernard, and Andrés Finzi. “Beyond Viral Neutralization..” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 760–64. https://doi.org/10.1089/AID.2016.0299.
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  - Meyerhoff, R Ryan, Richard M. Scearce, Damon F. Ogburn, Brad Lockwood, Joy Pickeral, Masa Kuraoka, Kara Anasti, et al. “HIV-1 Consensus Envelope-Induced Broadly Binding Antibodies..” Aids Res Hum Retroviruses 33, no. 8 (August 2017): 859–68. https://doi.org/10.1089/AID.2016.0294.
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  - Bradley, Todd, Justin Pollara, Sampa Santra, Nathan Vandergrift, Srivamshi Pittala, Chris Bailey-Kellogg, Xiaoying Shen, et al. “Pentavalent HIV-1 vaccine protects against simian-human immunodeficiency virus challenge..” Nat Commun 8 (June 8, 2017). https://doi.org/10.1038/ncomms15711.
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  - Wang, Chu, Chunlai Jiang, Nan Gao, Kaikai Zhang, Donglai Liu, Wei Wang, Zhe Cong, et al. “Immunologic and Virologic Mechanisms for Partial Protection from Intravenous Challenge by an Integration-Defective SIV Vaccine..” Viruses 9, no. 6 (June 2, 2017). https://doi.org/10.3390/v9060135.
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  - Shubin, Zhanna, Weizhong Li, Bhawna Poonia, Guido Ferrari, Celia LaBranche, David Montefiori, Xiaoping Zhu, and C David Pauza. “An HIV Envelope gp120-Fc Fusion Protein Elicits Effector Antibody Responses in Rhesus Macaques..” Clin Vaccine Immunol 24, no. 6 (June 2017). https://doi.org/10.1128/CVI.00028-17.
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  - García-Arriaza, Juan, Beatriz Perdiguero, Jonathan L. Heeney, Michael S. Seaman, David C. Montefiori, Nicole L. Yates, Georgia D. Tomaras, et al. “HIV/AIDS Vaccine Candidates Based on Replication-Competent Recombinant Poxvirus NYVAC-C-KC Expressing Trimeric gp140 and Gag-Derived Virus-Like Particles or Lacking the Viral Molecule B19 That Inhibits Type I Interferon Activate Relevant HIV-1-Specific B and T Cell Immune Functions in Nonhuman Primates..” J Virol 91, no. 9 (May 1, 2017). https://doi.org/10.1128/JVI.02182-16.
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  - Zurawski, Gerard, Xiaoying Shen, Sandra Zurawski, Georgia D. Tomaras, David C. Montefiori, Mario Roederer, Guido Ferrari, et al. “Superiority in Rhesus Macaques of Targeting HIV-1 Env gp140 to CD40 versus LOX-1 in Combination with Replication-Competent NYVAC-KC for Induction of Env-Specific Antibody and T Cell Responses..” J Virol 91, no. 9 (May 1, 2017). https://doi.org/10.1128/JVI.01596-16.
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  - Ferrari, Guido, Justin Pollara, Georgia D. Tomaras, and Barton F. Haynes. “Humoral and Innate Antiviral Immunity as Tools to Clear Persistent HIV Infection..” J Infect Dis 215, no. suppl_3 (March 15, 2017): S152–59. https://doi.org/10.1093/infdis/jiw555.
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  - Chege, Gerald K., Wendy A. Burgers, Tracey L. Müller, Clive M. Gray, Enid G. Shephard, Susan W. Barnett, Guido Ferrari, David Montefiori, Carolyn Williamson, and Anna-Lise Williamson. “DNA-MVA-protein vaccination of rhesus macaques induces HIV-specific immunity in mucosal-associated lymph nodes and functional antibodies..” Vaccine 35, no. 6 (February 7, 2017): 929–37. https://doi.org/10.1016/j.vaccine.2016.12.060.
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  - Easterhoff, David, M Anthony Moody, Daniela Fera, Hao Cheng, Margaret Ackerman, Kevin Wiehe, Kevin O. Saunders, et al. “Boosting of HIV envelope CD4 binding site antibodies with long variable heavy third complementarity determining region in the randomized double blind RV305 HIV-1 vaccine trial..” Plos Pathog 13, no. 2 (February 2017). https://doi.org/10.1371/journal.ppat.1006182.
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  - Buchbinder, Susan P., Nicole A. Grunenberg, Brittany J. Sanchez, Kelly E. Seaton, Guido Ferrari, M Anthony Moody, Nicole Frahm, et al. “Immunogenicity of a novel Clade B HIV-1 vaccine combination: Results of phase 1 randomized placebo controlled trial of an HIV-1 GM-CSF-expressing DNA prime with a modified vaccinia Ankara vaccine boost in healthy HIV-1 uninfected adults..” Plos One 12, no. 7 (2017). https://doi.org/10.1371/journal.pone.0179597.
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  - Ferrari, G. “Meet our editorial board member.” Current Hiv Research 15, no. 1 (January 1, 2017). https://doi.org/10.2174/1570162X1501170120194811.
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  - Hankins, Catherine A., Sinata Koulla-Shiro, Peter Kilmarx, Guido Ferrari, Mauro Schechter, Coumba Touré Kane, François Venter, et al. “Ending AIDS as a public health threat by 2030: Scientific Developments from the 2016 INTEREST Conference in Yaoundé, Cameroon..” Antivir Ther 22, no. 2 (2017): 179–84. https://doi.org/10.3851/IMP3165.
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  - Margolis, David M., Richard A. Koup, and Guido Ferrari. “HIV antibodies for treatment of HIV infection..” Immunol Rev 275, no. 1 (January 2017): 313–23. https://doi.org/10.1111/imr.12506.
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  - Huang, Yunda, Guido Ferrari, Galit Alter, Donald N. Forthal, John C. Kappes, George K. Lewis, J Christopher Love, et al. “Diversity of Antiviral IgG Effector Activities Observed in HIV-Infected and Vaccinated Subjects..” J Immunol 197, no. 12 (December 15, 2016): 4603–12. https://doi.org/10.4049/jimmunol.1601197.
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  - Luo, Kan, Hua-Xin Liao, Ruijun Zhang, David Easterhoff, Kevin Wiehe, Thaddeus C. Gurley, Lawrence C. Armand, et al. “Tissue memory B cell repertoire analysis after ALVAC/AIDSVAX B/E gp120 immunization of rhesus macaques..” Jci Insight 1, no. 20 (December 8, 2016). https://doi.org/10.1172/jci.insight.88522.
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  - Astronomo, Rena D., Sampa Santra, Lamar Ballweber-Fleming, Katharine G. Westerberg, Linh Mach, Tiffany Hensley-McBain, Laura Sutherland, et al. “Neutralization Takes Precedence Over IgG or IgA Isotype-related Functions in Mucosal HIV-1 Antibody-mediated Protection..” Ebiomedicine 14 (December 2016): 97–111. https://doi.org/10.1016/j.ebiom.2016.11.024.
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  - Ferrari, Guido, Barton F. Haynes, Scott Koenig, Jeffrey L. Nordstrom, David M. Margolis, and Georgia D. Tomaras. “Envelope-specific antibodies and antibody-derived molecules for treating and curing HIV infection..” Nat Rev Drug Discov 15, no. 12 (December 2016): 823–34. https://doi.org/10.1038/nrd.2016.173.
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  - Gay, Cynthia L., Sarah J. Willis, Anna B. Cope, JoAnn D. Kuruc, Kara S. McGee, Joe Sebastian, Amanda M. Crooks, et al. “Fixed-dose combination emtricitabine/tenofovir/efavirenz initiated during acute HIV infection; 96-week efficacy and durability..” Aids 30, no. 18 (November 28, 2016): 2815–22. https://doi.org/10.1097/QAD.0000000000001255.
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  - Altenburg, Arwen F., Carolien E. van de Sandt, Stella E. van Trierum, Heidi L. M. De Gruyter, Peter R. W. A. van Run, Ron A. M. Fouchier, Kenny Roose, et al. “Increased Protein Degradation Improves Influenza Virus Nucleoprotein-Specific CD8+ T Cell Activation In Vitro but Not in C57BL/6 Mice..” J Virol 90, no. 22 (November 15, 2016): 10209–19. https://doi.org/10.1128/JVI.01633-16.
    Full Text Link to Item
  - Costa, Matthew R., Justin Pollara, Regina Whitney Edwards, Michael S. Seaman, Miroslaw K. Gorny, David C. Montefiori, Hua-Xin Liao, Guido Ferrari, Shan Lu, and Shixia Wang. “Fc Receptor-Mediated Activities of Env-Specific Human Monoclonal Antibodies Generated from Volunteers Receiving the DNA Prime-Protein Boost HIV Vaccine DP6-001..” J Virol 90, no. 22 (November 15, 2016): 10362–78. https://doi.org/10.1128/JVI.01458-16.
    Full Text Link to Item
  - Negri, Donatella, Maria Blasi, Celia LaBranche, Robert Parks, Harikrishnan Balachandran, Michelle Lifton, Xiaoying Shen, et al. “Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques..” Mol Ther 24, no. 11 (November 2016): 2021–32. https://doi.org/10.1038/mt.2016.123.
    Full Text Open Access Copy Link to Item
  - Nemes, Elisa, Wendy A. Burgers, Catherine Riou, Erica Andersen-Nissen, Guido Ferrari, Clive M. Gray, and Thomas Scriba. “Teaching advanced flow cytometry in Africa: 10 years of lessons learned..” Cytometry A 89, no. 11 (November 2016): 971–74. https://doi.org/10.1002/cyto.a.23015.
    Full Text Link to Item
  - Negri, D, Blasi, M, LaBranche, C, Parks, R, Balachandran, H, Lifton, M, Shen, X, Denny, T, Ferrari, G, Vescio, MF, Andersen, H, Montefiori, DC, Tomaras, GD, Liao, H-X, Santra, S, Haynes, BF, Klotman, ME, and Cara, A. "Immunization with an SIV-based IDLV Expressing HIV-1 Env 1086 Clade C Elicits Durable Humoral and Cellular Responses in Rhesus Macaques." MOLECULAR THERAPY 24, no. 11 (November 2016): 2021-2032. Full Text Open Access Copy Link to Item
  - Vaccari, Monica, Shari N. Gordon, Slim Fourati, Luca Schifanella, Namal P. M. Liyanage, Mark Cameron, Brandon F. Keele, et al. “Corrigendum: Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition..” Nat Med 22, no. 10 (October 6, 2016). https://doi.org/10.1038/nm1016-1192a.
    Full Text Link to Item
  - Gordon, Shari N., Namal P. M. Liyanage, Melvin N. Doster, Monica Vaccari, Diego A. Vargas-Inchaustegui, Poonam Pegu, Luca Schifanella, et al. “Boosting of ALVAC-SIV Vaccine-Primed Macaques with the CD4-SIVgp120 Fusion Protein Elicits Antibodies to V2 Associated with a Decreased Risk of SIVmac251 Acquisition..” J Immunol 197, no. 7 (October 1, 2016): 2726–37. https://doi.org/10.4049/jimmunol.1600674.
    Full Text Link to Item
  - Townsley, Samantha, Zeinab Mohamed, Wenjin Guo, Jennifer McKenna, Brad Cleveland, Celia LaBranche, David Beaumont, et al. “Induction of Heterologous Tier 2 HIV-1-Neutralizing and Cross-Reactive V1/V2-Specific Antibodies in Rabbits by Prime-Boost Immunization..” J Virol 90, no. 19 (October 1, 2016): 8644–60. https://doi.org/10.1128/JVI.00853-16.
    Full Text Link to Item
  - Zhang, Ruijun, David R. Martinez, Quang N. Nguyen, Justin Pollara, Trina Arifin, Christina Stolarchuk, Andrew Foulger, et al. “Envelope-specific B-cell populations in African green monkeys chronically infected with simian immunodeficiency virus..” Nat Commun 7 (July 6, 2016). https://doi.org/10.1038/ncomms12131.
    Full Text Link to Item
  - Vaccari, Monica, Shari N. Gordon, Slim Fourati, Luca Schifanella, Namal P. M. Liyanage, Mark Cameron, Brandon F. Keele, et al. “Adjuvant-dependent innate and adaptive immune signatures of risk of SIVmac251 acquisition..” Nat Med 22, no. 7 (July 2016): 762–70. https://doi.org/10.1038/nm.4105.
    Full Text Link to Item
  - Rountree, Wes, Mark Berrong, Ana M. Sanchez, Thomas N. Denny, and Guido Ferrari. “Variability of the IFN-γ ELISpot assay in the context of proficiency testing and bridging studies..” J Immunol Methods 433 (June 2016): 69–76. https://doi.org/10.1016/j.jim.2016.03.004.
    Full Text Open Access Copy Link to Item
  - Nelson, Cody S., Justin Pollara, Erika L. Kunz, Thomas L. Jeffries, Ryan Duffy, Charles Beck, Lisa Stamper, et al. “Combined HIV-1 Envelope Systemic and Mucosal Immunization of Lactating Rhesus Monkeys Induces a Robust Immunoglobulin A Isotype B Cell Response in Breast Milk..” J Virol 90, no. 10 (May 15, 2016): 4951–65. https://doi.org/10.1128/JVI.00335-16.
    Full Text Link to Item
  - Asbach, Benedikt, Alexander Kliche, Josef Köstler, Beatriz Perdiguero, Mariano Esteban, Bertram L. Jacobs, David C. Montefiori, et al. “Potential To Streamline Heterologous DNA Prime and NYVAC/Protein Boost HIV Vaccine Regimens in Rhesus Macaques by Employing Improved Antigens..” J Virol 90, no. 8 (April 2016): 4133–49. https://doi.org/10.1128/JVI.03135-15.
    Full Text Open Access Copy Link to Item
  - Jeffries, T. L., C. R. Sacha, J. Pollara, J. Himes, F. H. Jaeger, S. M. Dennison, E. McGuire, et al. “The function and affinity maturation of HIV-1 gp120-specific monoclonal antibodies derived from colostral B cells..” Mucosal Immunol 9, no. 2 (March 2016): 414–27. https://doi.org/10.1038/mi.2015.70.
    Full Text Link to Item
  - Ding, Shilei, Maxime Veillette, Mathieu Coutu, Jérémie Prévost, Louise Scharf, Pamela J. Bjorkman, Guido Ferrari, et al. “A Highly Conserved Residue of the HIV-1 gp120 Inner Domain Is Important for Antibody-Dependent Cellular Cytotoxicity Responses Mediated by Anti-cluster A Antibodies..” J Virol 90, no. 4 (February 15, 2016): 2127–34. https://doi.org/10.1128/JVI.02779-15.
    Full Text Link to Item
  - Cosgrove, Catherine A., Charles J. Lacey, Alethea V. Cope, Angela Bartolf, Georgina Morris, Celine Yan, Susan Baden, et al. “Comparative Immunogenicity of HIV-1 gp140 Vaccine Delivered by Parenteral, and Mucosal Routes in Female Volunteers; MUCOVAC2, A Randomized Two Centre Study..” Plos One 11, no. 5 (2016). https://doi.org/10.1371/journal.pone.0152038.
    Full Text Link to Item
  - Joachim, Agricola, Asli Bauer, Sarah Joseph, Christof Geldmacher, Patricia J. Munseri, Said Aboud, Marco Missanga, et al. “Boosting with Subtype C CN54rgp140 Protein Adjuvanted with Glucopyranosyl Lipid Adjuvant after Priming with HIV-DNA and HIV-MVA Is Safe and Enhances Immune Responses: A Phase I Trial..” Plos One 11, no. 5 (2016). https://doi.org/10.1371/journal.pone.0155702.
    Full Text Link to Item
  - Zurawski, Gerard, Sandra Zurawski, Anne-Laure Flamar, Laura Richert, Ralf Wagner, Georgia D. Tomaras, David C. Montefiori, et al. “Targeting HIV-1 Env gp140 to LOX-1 Elicits Immune Responses in Rhesus Macaques..” Plos One 11, no. 4 (2016). https://doi.org/10.1371/journal.pone.0153484.
    Full Text Link to Item
  - Lai, Weihong, Li Huang, Lei Zhu, Guido Ferrari, Cliburn Chan, Wei Li, Kuo-Hsiung Lee, and Chin-Ho Chen. “Gnidimacrin, a Potent Anti-HIV Diterpene, Can Eliminate Latent HIV-1 Ex Vivo by Activation of Protein Kinase C β..” J Med Chem 58, no. 21 (November 12, 2015): 8638–46. https://doi.org/10.1021/acs.jmedchem.5b01233.
    Full Text Link to Item
  - Sung, Julia A. M., Joy Pickeral, Liqin Liu, Sherry A. Stanfield-Oakley, Chia-Ying Kao Lam, Carolina Garrido, Justin Pollara, et al. “Dual-Affinity Re-Targeting proteins direct T cell-mediated cytolysis of latently HIV-infected cells..” J Clin Invest 125, no. 11 (November 2, 2015): 4077–90. https://doi.org/10.1172/JCI82314.
    Full Text Link to Item
  - Pollara, Justin, Erin McGuire, Genevieve G. Fouda, Wes Rountree, Josh Eudailey, R Glenn Overman, Kelly E. Seaton, et al. “Association of HIV-1 Envelope-Specific Breast Milk IgA Responses with Reduced Risk of Postnatal Mother-to-Child Transmission of HIV-1..” J Virol 89, no. 19 (October 2015): 9952–61. https://doi.org/10.1128/JVI.01560-15.
    Full Text Open Access Copy Link to Item
  - Moody, M Anthony, Feng Gao, Thaddeus C. Gurley, Joshua D. Amos, Amit Kumar, Bhavna Hora, Dawn J. Marshall, et al. “Strain-Specific V3 and CD4 Binding Site Autologous HIV-1 Neutralizing Antibodies Select Neutralization-Resistant Viruses..” Cell Host Microbe 18, no. 3 (September 9, 2015): 354–62. https://doi.org/10.1016/j.chom.2015.08.006.
    Full Text Link to Item
  - Wise, Megan C., Natalie A. Hutnick, Justin Pollara, Devin J. F. Myles, Constance Williams, Jian Yan, Celia C. LaBranche, et al. “An Enhanced Synthetic Multiclade DNA Prime Induces Improved Cross-Clade-Reactive Functional Antibodies when Combined with an Adjuvanted Protein Boost in Nonhuman Primates..” J Virol 89, no. 18 (September 2015): 9154–66. https://doi.org/10.1128/JVI.00652-15.
    Full Text Link to Item
  - Williams, Wilton B., Hua-Xin Liao, M Anthony Moody, Thomas B. Kepler, S Munir Alam, Feng Gao, Kevin Wiehe, et al. “HIV-1 VACCINES. Diversion of HIV-1 vaccine-induced immunity by gp41-microbiota cross-reactive antibodies..” Science 349, no. 6249 (August 14, 2015). https://doi.org/10.1126/science.aab1253.
    Full Text Link to Item
  - García-Arriaza, Juan, Beatriz Perdiguero, Jonathan Heeney, Michael Seaman, David C. Montefiori, Celia Labranche, Nicole L. Yates, et al. “Head-to-Head Comparison of Poxvirus NYVAC and ALVAC Vectors Expressing Identical HIV-1 Clade C Immunogens in Prime-Boost Combination with Env Protein in Nonhuman Primates..” J Virol 89, no. 16 (August 2015): 8525–39. https://doi.org/10.1128/JVI.01265-15.
    Full Text Link to Item
  - Santra, Sampa, Georgia D. Tomaras, Ranjit Warrier, Nathan I. Nicely, Hua-Xin Liao, Justin Pollara, Pinghuang Liu, et al. “Human Non-neutralizing HIV-1 Envelope Monoclonal Antibodies Limit the Number of Founder Viruses during SHIV Mucosal Infection in Rhesus Macaques..” Plos Pathog 11, no. 8 (August 2015). https://doi.org/10.1371/journal.ppat.1005042.
    Full Text Open Access Copy Link to Item
  - Prentice, Heather A., Georgia D. Tomaras, Daniel E. Geraghty, Richard Apps, Youyi Fong, Philip K. Ehrenberg, Morgane Rolland, et al. “HLA class II genes modulate vaccine-induced antibody responses to affect HIV-1 acquisition..” Sci Transl Med 7, no. 296 (July 15, 2015). https://doi.org/10.1126/scitranslmed.aab4005.
    Full Text Link to Item
  - Permar, Sallie R., Youyi Fong, Nathan Vandergrift, Genevieve G. Fouda, Peter Gilbert, Robert Parks, Frederick H. Jaeger, et al. “Maternal HIV-1 envelope-specific antibody responses and reduced risk of perinatal transmission..” J Clin Invest 125, no. 7 (July 1, 2015): 2702–6. https://doi.org/10.1172/JCI81593.
    Full Text Open Access Copy Link to Item
  - Fouda, Genevieve G., Coleen K. Cunningham, Elizabeth J. McFarland, William Borkowsky, Petronella Muresan, Justin Pollara, Lin Ye Song, et al. “Infant HIV type 1 gp120 vaccination elicits robust and durable anti-V1V2 immunoglobulin G responses and only rare envelope-specific immunoglobulin A responses..” J Infect Dis 211, no. 4 (February 15, 2015): 508–17. https://doi.org/10.1093/infdis/jiu444.
    Full Text Link to Item
  - Hancock, Gemma, Hongbing Yang, Elisabeth Yorke, Emma Wainwright, Victoria Bourne, Alyse Frisbee, Tamika L. Payne, et al. “Identification of effective subdominant anti-HIV-1 CD8+ T cells within entire post-infection and post-vaccination immune responses..” Plos Pathog 11, no. 2 (February 2015). https://doi.org/10.1371/journal.ppat.1004658.
    Full Text Link to Item
  - Joachim, Agricola, Charlotta Nilsson, Said Aboud, Muhammad Bakari, Eligius F. Lyamuya, Merlin L. Robb, Mary A. Marovich, et al. “Potent functional antibody responses elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults..” Plos One 10, no. 4 (2015). https://doi.org/10.1371/journal.pone.0118486.
    Full Text Open Access Copy Link to Item
  - Gordon, Shari N., Melvin N. Doster, Rhonda C. Kines, Brandon F. Keele, Egidio Brocca-Cofano, Yongjun Guan, Poonam Pegu, et al. “Antibody to the gp120 V1/V2 loops and CD4+ and CD8+ T cell responses in protection from SIVmac251 vaginal acquisition and persistent viremia..” J Immunol 193, no. 12 (December 15, 2014): 6172–83. https://doi.org/10.4049/jimmunol.1401504.
    Full Text Link to Item
  - Stieh, Daniel J., Deborah F. King, Katja Klein, Pinghuang Liu, Xiaoying Shen, Kwan Ki Hwang, Guido Ferrari, et al. “Aggregate complexes of HIV-1 induced by multimeric antibodies..” Retrovirology 11 (October 2, 2014). https://doi.org/10.1186/s12977-014-0078-8.
    Full Text Open Access Copy Link to Item
  - Li, Shuying S., Peter B. Gilbert, Georgia D. Tomaras, Gustavo Kijak, Guido Ferrari, Rasmi Thomas, Chul-Woo Pyo, et al. “FCGR2C polymorphisms associate with HIV-1 vaccine protection in RV144 trial..” J Clin Invest 124, no. 9 (September 2014): 3879–90. https://doi.org/10.1172/JCI75539.
    Full Text Link to Item
  - Payne, Tamika L., Jeff Blackinton, Alyse Frisbee, Joy Pickeral, Sheetal Sawant, Nathan A. Vandergrift, Stephanie A. Freel, Guido Ferrari, Jack D. Keene, and Georgia D. Tomaras. “Transcriptional and posttranscriptional regulation of cytokine gene expression in HIV-1 antigen-specific CD8+ T cells that mediate virus inhibition..” J Virol 88, no. 17 (September 1, 2014): 9514–28. https://doi.org/10.1128/JVI.00802-14.
    Full Text Link to Item
  - Dennison, S Moses, Kara M. Anasti, Frederick H. Jaeger, Shelley M. Stewart, Justin Pollara, Pinghuang Liu, Erika L. Kunz, et al. “Vaccine-induced HIV-1 envelope gp120 constant region 1-specific antibodies expose a CD4-inducible epitope and block the interaction of HIV-1 gp140 with galactosylceramide..” J Virol 88, no. 16 (August 2014): 9406–17. https://doi.org/10.1128/JVI.01031-14.
    Full Text Link to Item
  - Haynes, Barton F., M Anthony Moody, Munir Alam, Mattia Bonsignori, Laurent Verkoczy, Guido Ferrari, Feng Gao, Georgia D. Tomaras, Hua-Xin Liao, and Garnett Kelsoe. “Progress in HIV-1 vaccine development..” J Allergy Clin Immunol 134, no. 1 (July 2014): 3–10. https://doi.org/10.1016/j.jaci.2014.04.025.
    Full Text Link to Item
  - Pollara, Justin, Mattia Bonsignori, M Anthony Moody, Pinghuang Liu, S Munir Alam, Kwan-Ki Hwang, Thaddeus C. Gurley, et al. “HIV-1 vaccine-induced C1 and V2 Env-specific antibodies synergize for increased antiviral activities..” J Virol 88, no. 14 (July 2014): 7715–26. https://doi.org/10.1128/JVI.00156-14.
    Full Text Link to Item
  - Yates, Nicole L., Hua-Xin Liao, Youyi Fong, Allan deCamp, Nathan A. Vandergrift, William T. Williams, S Munir Alam, et al. “Vaccine-induced Env V1-V2 IgG3 correlates with lower HIV-1 infection risk and declines soon after vaccination..” Sci Transl Med 6, no. 228 (March 19, 2014). https://doi.org/10.1126/scitranslmed.3007730.
    Full Text Link to Item
  - Moody, M Anthony, Sampa Santra, Nathan A. Vandergrift, Laura L. Sutherland, Thaddeus C. Gurley, Mark S. Drinker, Ashley A. Allen, et al. “Toll-like receptor 7/8 (TLR7/8) and TLR9 agonists cooperate to enhance HIV-1 envelope antibody responses in rhesus macaques..” J Virol 88, no. 6 (March 2014): 3329–39. https://doi.org/10.1128/JVI.03309-13.
    Full Text Link to Item
  - Roederer, Mario, Brandon F. Keele, Stephen D. Schmidt, Rosemarie D. Mason, Hugh C. Welles, Will Fischer, Celia Labranche, et al. “Immunological and virological mechanisms of vaccine-mediated protection against SIV and HIV..” Nature 505, no. 7484 (January 23, 2014): 502–8. https://doi.org/10.1038/nature12893.
    Full Text Open Access Copy Link to Item
  - Perley, Casey C., Marc Frahm, Eva M. Click, Karen M. Dobos, Guido Ferrari, Jason E. Stout, and Richard Frothingham. “The human antibody response to the surface of Mycobacterium tuberculosis..” Plos One 9, no. 2 (2014). https://doi.org/10.1371/journal.pone.0098938.
    Full Text Open Access Copy Link to Item
  - Liu, Pinghuang, Nicole L. Yates, Xiaoying Shen, Mattia Bonsignori, M Anthony Moody, Hua-Xin Liao, Youyi Fong, et al. “Infectious virion capture by HIV-1 gp120-specific IgG from RV144 vaccinees..” J Virol 87, no. 14 (July 2013): 7828–36. https://doi.org/10.1128/JVI.02737-12.
    Full Text Open Access Copy Link to Item
  - Pollara, Justin, Mattia Bonsignori, M Anthony Moody, Marzena Pazgier, Barton F. Haynes, and Guido Ferrari. “Epitope specificity of human immunodeficiency virus-1 antibody dependent cellular cytotoxicity [ADCC] responses..” Curr Hiv Res 11, no. 5 (July 2013): 378–87.
    Link to Item
  - Fouda, Genevieve G. A., Joshua D. Amos, Andrew B. Wilks, Justin Pollara, Caroline A. Ray, Anjali Chand, Erika L. Kunz, et al. “Mucosal immunization of lactating female rhesus monkeys with a transmitted/founder HIV-1 envelope induces strong Env-specific IgA antibody responses in breast milk..” J Virol 87, no. 12 (June 2013): 6986–99. https://doi.org/10.1128/JVI.00528-13.
    Full Text Link to Item
  - Tomaras, Georgia D., Guido Ferrari, Xiaoying Shen, S Munir Alam, Hua-Xin Liao, Justin Pollara, Mattia Bonsignori, et al. “Vaccine-induced plasma IgA specific for the C1 region of the HIV-1 envelope blocks binding and effector function of IgG..” Proc Natl Acad Sci U S A 110, no. 22 (May 28, 2013): 9019–24. https://doi.org/10.1073/pnas.1301456110.
    Full Text Link to Item
  - Vaccari, Monica, Brandon F. Keele, Steven E. Bosinger, Melvin N. Doster, Zhong-Min Ma, Justin Pollara, Anna Hryniewicz, et al. “Protection afforded by an HIV vaccine candidate in macaques depends on the dose of SIVmac251 at challenge exposure..” J Virol 87, no. 6 (March 2013): 3538–48. https://doi.org/10.1128/JVI.02863-12.
    Full Text Link to Item
  - Pegu, Poonam, Monica Vaccari, Shari Gordon, Brandon F. Keele, Melvin Doster, Yongjun Guan, Guido Ferrari, et al. “Antibodies with high avidity to the gp120 envelope protein in protection from simian immunodeficiency virus SIV(mac251) acquisition in an immunization regimen that mimics the RV-144 Thai trial..” J Virol 87, no. 3 (February 2013): 1708–19. https://doi.org/10.1128/JVI.02544-12.
    Full Text Link to Item
  - Liao, Hua-Xin, Mattia Bonsignori, S Munir Alam, Jason S. McLellan, Georgia D. Tomaras, M Anthony Moody, Daniel M. Kozink, et al. “Vaccine induction of antibodies against a structurally heterogeneous site of immune pressure within HIV-1 envelope protein variable regions 1 and 2..” Immunity 38, no. 1 (January 24, 2013): 176–86. https://doi.org/10.1016/j.immuni.2012.11.011.
    Full Text Link to Item
  - Lambotte, Olivier, Justin Pollara, Faroudy Boufassa, Christiane Moog, Alain Venet, Barton F. Haynes, Jean-François Delfraissy, Asier Saez-Cirion, and Guido Ferrari. “High antibody-dependent cellular cytotoxicity responses are correlated with strong CD8 T cell viral suppressive activity but not with B57 status in HIV-1 elite controllers..” Plos One 8, no. 9 (2013). https://doi.org/10.1371/journal.pone.0074855.
    Full Text Link to Item
  - Liu, Michael K. P., Natalie Hawkins, Adam J. Ritchie, Vitaly V. Ganusov, Victoria Whale, Simon Brackenridge, Hui Li, et al. “Vertical T cell immunodominance and epitope entropy determine HIV-1 escape..” J Clin Invest 123, no. 1 (January 2013): 380–93. https://doi.org/10.1172/JCI65330.
    Full Text Link to Item
  - McKellar, Mehri S., Anna B. Cope, Cynthia L. Gay, Kara S. McGee, Joann D. Kuruc, Melissa G. Kerkau, Christopher B. Hurt, et al. “Acute HIV-1 infection in the Southeastern United States: a cohort study..” Aids Res Hum Retroviruses 29, no. 1 (January 2013): 121–28. https://doi.org/10.1089/aid.2012.0064.
    Full Text Link to Item
  - Weaver, Eric A., Pramod N. Nehete, Bharti P. Nehete, Guojun Yang, Stephanie J. Buchl, Patrick W. Hanley, Donna Palmer, et al. “Comparison of systemic and mucosal immunization with helper-dependent adenoviruses for vaccination against mucosal challenge with SHIV..” Plos One 8, no. 7 (2013). https://doi.org/10.1371/journal.pone.0067574.
    Full Text Link to Item
  - Bonsignori, Mattia, Justin Pollara, M Anthony Moody, Michael D. Alpert, Xi Chen, Kwan-Ki Hwang, Peter B. Gilbert, et al. “Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial target multiple epitopes and preferentially use the VH1 gene family..” J Virol 86, no. 21 (November 2012): 11521–32. https://doi.org/10.1128/JVI.01023-12.
    Full Text Link to Item
  - Fukazawa, Yoshinori, Haesun Park, Mark J. Cameron, Francois Lefebvre, Richard Lum, Noel Coombes, Eisa Mahyari, et al. “Lymph node T cell responses predict the efficacy of live attenuated SIV vaccines..” Nat Med 18, no. 11 (November 2012): 1673–81. https://doi.org/10.1038/nm.2934.
    Full Text Link to Item
  - Song, Hongshuo, Jeffrey W. Pavlicek, Fangping Cai, Tanmoy Bhattacharya, Hui Li, Shilpa S. Iyer, Katharine J. Bar, et al. “Impact of immune escape mutations on HIV-1 fitness in the context of the cognate transmitted/founder genome..” Retrovirology 9 (October 30, 2012). https://doi.org/10.1186/1742-4690-9-89.
    Full Text Link to Item
  - Arnoczy, Gretchen S., Guido Ferrari, Nilu Goonetilleke, Tumena Corrah, Hui Li, Joann Kuruc, John L. Schmitz, et al. “Massive CD8 T cell response to primary HIV infection in the setting of severe clinical presentation..” Aids Res Hum Retroviruses 28, no. 8 (August 2012): 789–92. https://doi.org/10.1089/AID.2011.0145.
    Full Text Link to Item
  - Britten, C. M., S. Janetzki, L. H. Butterfield, G. Ferrari, C. Gouttefangeas, C. Huber, M. Kalos, et al. “T cell assays and MIATA: the essential minimum for maximum impact..” Immunity 37, no. 1 (July 27, 2012): 1–2. https://doi.org/10.1016/j.immuni.2012.07.010.
    Full Text Link to Item
  - Moody, M Anthony, Nicole L. Yates, Joshua D. Amos, Mark S. Drinker, Joshua A. Eudailey, Thaddeus C. Gurley, Dawn J. Marshall, et al. “HIV-1 gp120 vaccine induces affinity maturation in both new and persistent antibody clonal lineages..” J Virol 86, no. 14 (July 2012): 7496–7507. https://doi.org/10.1128/JVI.00426-12.
    Full Text Link to Item
  - Freel, Stephanie A., Ralph A. Picking, Guido Ferrari, Haitao Ding, Christina Ochsenbauer, John C. Kappes, Jennifer L. Kirchherr, et al. “Initial HIV-1 antigen-specific CD8+ T cells in acute HIV-1 infection inhibit transmitted/founder virus replication..” J Virol 86, no. 12 (June 2012): 6835–46. https://doi.org/10.1128/JVI.00437-12.
    Full Text Open Access Copy Link to Item
  - Frahm, Marc A., Ralph A. Picking, JoAnn D. Kuruc, Kara S. McGee, Cynthia L. Gay, Joseph J. Eron, Charles B. Hicks, Georgia D. Tomaras, and Guido Ferrari. “CD4+CD8+ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection..” J Immunol 188, no. 9 (May 1, 2012): 4289–96. https://doi.org/10.4049/jimmunol.1103701.
    Full Text Link to Item
  - Moiani, Arianna, Ylenia Paleari, Daniela Sartori, Riccardo Mezzadra, Annarita Miccio, Claudia Cattoglio, Fabienne Cocchiarella, Maria Rosa Lidonnici, Giuliana Ferrari, and Fulvio Mavilio. “Lentiviral vector integration in the human genome induces alternative splicing and generates aberrant transcripts..” J Clin Invest 122, no. 5 (May 2012): 1653–66. https://doi.org/10.1172/JCI61852.
    Full Text Link to Item
  - Haynes, Barton F., Peter B. Gilbert, M Juliana McElrath, Susan Zolla-Pazner, Georgia D. Tomaras, S Munir Alam, David T. Evans, et al. “Immune-correlates analysis of an HIV-1 vaccine efficacy trial..” N Engl J Med 366, no. 14 (April 5, 2012): 1275–86. https://doi.org/10.1056/NEJMoa1113425.
    Full Text Link to Item
  - Riou, Catherine, Vitaly V. Ganusov, Suzanne Campion, Mandla Mlotshwa, Michael K. P. Liu, Victoria E. Whale, Nilu Goonetilleke, et al. “Distinct kinetics of Gag-specific CD4+ and CD8+ T cell responses during acute HIV-1 infection..” J Immunol 188, no. 5 (March 1, 2012): 2198–2206. https://doi.org/10.4049/jimmunol.1102813.
    Full Text Link to Item
  - Cox, Josephine H., Maria G. Ferrari, Patricia Earl, James R. Lane, Linda L. Jagodzinski, Victoria R. Polonis, Ellen G. Kuta, et al. “Inclusion of a CRF01_AE HIV envelope protein boost with a DNA/MVA prime-boost vaccine: Impact on humoral and cellular immunogenicity and viral load reduction after SHIV-E challenge..” Vaccine 30, no. 10 (February 27, 2012): 1830–40. https://doi.org/10.1016/j.vaccine.2011.12.131.
    Full Text Link to Item
  - Lai, Lilin, Sue-Fen Kwa, Pamela A. Kozlowski, David C. Montefiori, Tracy L. Nolen, Michael G. Hudgens, Welkin E. Johnson, et al. “SIVmac239 MVA vaccine with and without a DNA prime, similar prevention of infection by a repeated dose SIVsmE660 challenge despite different immune responses..” Vaccine 30, no. 9 (February 21, 2012): 1737–45. https://doi.org/10.1016/j.vaccine.2011.12.026.
    Full Text Link to Item
  - Barouch, Dan H., Jinyan Liu, Hualin Li, Lori F. Maxfield, Peter Abbink, Diana M. Lynch, M Justin Iampietro, et al. “Vaccine protection against acquisition of neutralization-resistant SIV challenges in rhesus monkeys..” Nature 482, no. 7383 (January 4, 2012): 89–93. https://doi.org/10.1038/nature10766.
    Full Text Link to Item
  - Friedman, James, S Munir Alam, Xiaoying Shen, Shi-Mao Xia, Shelley Stewart, Kara Anasti, Justin Pollara, et al. “Isolation of HIV-1-neutralizing mucosal monoclonal antibodies from human colostrum..” Plos One 7, no. 5 (2012). https://doi.org/10.1371/journal.pone.0037648.
    Full Text Open Access Copy Link to Item
  - Ganusov, Vitaly V., Nilu Goonetilleke, Michael K. P. Liu, Guido Ferrari, George M. Shaw, Andrew J. McMichael, Persephone Borrow, Bette T. Korber, and Alan S. Perelson. “Fitness costs and diversity of the cytotoxic T lymphocyte (CTL) response determine the rate of CTL escape during acute and chronic phases of HIV infection..” J Virol 85, no. 20 (October 2011): 10518–28. https://doi.org/10.1128/JVI.00655-11.
    Full Text Link to Item
  - Fouda, Genevieve G., Nicole L. Yates, Justin Pollara, Xiaoying Shen, Glenn R. Overman, Tatenda Mahlokozera, Andrew B. Wilks, et al. “HIV-specific functional antibody responses in breast milk mirror those in plasma and are primarily mediated by IgG antibodies..” J Virol 85, no. 18 (September 2011): 9555–67. https://doi.org/10.1128/JVI.05174-11.
    Full Text Open Access Copy Link to Item
  - Pollara, Justin, Lydia Hart, Faraha Brewer, Joy Pickeral, Beverly Z. Packard, James A. Hoxie, Akira Komoriya, et al. “High-throughput quantitative analysis of HIV-1 and SIV-specific ADCC-mediating antibody responses..” Cytometry A 79, no. 8 (August 2011): 603–12. https://doi.org/10.1002/cyto.a.21084.
    Full Text Link to Item
  - Ferrari, Guido, Justin Pollara, Daniel Kozink, Tiara Harms, Mark Drinker, Stephanie Freel, M Anthony Moody, et al. “An HIV-1 gp120 envelope human monoclonal antibody that recognizes a C1 conformational epitope mediates potent antibody-dependent cellular cytotoxicity (ADCC) activity and defines a common ADCC epitope in human HIV-1 serum..” J Virol 85, no. 14 (July 2011): 7029–36. https://doi.org/10.1128/JVI.00171-11.
    Full Text Link to Item
  - Lai, Lilin, Suefen Kwa, Pamela A. Kozlowski, David C. Montefiori, Guido Ferrari, Welkin E. Johnson, Vanessa Hirsch, et al. “Prevention of infection by a granulocyte-macrophage colony-stimulating factor co-expressing DNA/modified vaccinia Ankara simian immunodeficiency virus vaccine..” J Infect Dis 204, no. 1 (July 1, 2011): 164–73. https://doi.org/10.1093/infdis/jir199.
    Full Text Link to Item
  - Gay, Cynthia, Oliver Dibben, Jeffrey A. Anderson, Andrea Stacey, Ashley J. Mayo, Philip J. Norris, JoAnn D. Kuruc, et al. “Cross-sectional detection of acute HIV infection: timing of transmission, inflammation and antiretroviral therapy..” Plos One 6, no. 5 (May 10, 2011). https://doi.org/10.1371/journal.pone.0019617.
    Full Text Link to Item
  - Yamamoto, Takuya, David A. Price, Joseph P. Casazza, Guido Ferrari, Martha Nason, Pratip K. Chattopadhyay, Mario Roederer, et al. “Surface expression patterns of negative regulatory molecules identify determinants of virus-specific CD8+ T-cell exhaustion in HIV infection..” Blood 117, no. 18 (May 5, 2011): 4805–15. https://doi.org/10.1182/blood-2010-11-317297.
    Full Text Link to Item
  - Frahm, Marc, Neela D. Goswami, Kouros Owzar, Emily Hecker, Ann Mosher, Emily Cadogan, Payam Nahid, Guido Ferrari, and Jason E. Stout. “Discriminating between latent and active tuberculosis with multiple biomarker responses..” Tuberculosis (Edinb) 91, no. 3 (May 2011): 250–56. https://doi.org/10.1016/j.tube.2011.02.006.
    Full Text Link to Item
  - Gay, Cynthia L., Ashley J. Mayo, Chelu K. Mfalila, Haitao Chu, Anna C. Barry, JoAnn D. Kuruc, Kara S. McGee, et al. “Efficacy of NNRTI-based antiretroviral therapy initiated during acute HIV infection..” Aids 25, no. 7 (April 24, 2011): 941–49. https://doi.org/10.1097/QAD.0b013e3283463c07.
    Full Text Link to Item
  - Ganusov, Vitaly, Nilu Goonetilleke, Michael Liu, Guido Ferrari, George Shaw, Andrew McMichael, Persephone Borrow, Bette Korber, and Alan Perelson. “Fitness costs and diversity of CTL response determine the rate of CTL escape during the acute and chronic phases of HIV infection.” Journal of Immunology 186 (April 1, 2011).
    Link to Item
  - Keefer, Michael C., Sharon E. Frey, Marnie Elizaga, Barbara Metch, Stephen C. De Rosa, Paulo F. Barroso, Georgia Tomaras, et al. “A phase I trial of preventive HIV vaccination with heterologous poxviral-vectors containing matching HIV-1 inserts in healthy HIV-uninfected subjects..” Vaccine 29, no. 10 (February 24, 2011): 1948–58. https://doi.org/10.1016/j.vaccine.2010.12.104.
    Full Text Link to Item
  - Ferrari, Guido, Bette Korber, Nilu Goonetilleke, Michael K. P. Liu, Emma L. Turnbull, Jesus F. Salazar-Gonzalez, Natalie Hawkins, et al. “Relationship between functional profile of HIV-1 specific CD8 T cells and epitope variability with the selection of escape mutants in acute HIV-1 infection..” Plos Pathog 7, no. 2 (February 10, 2011). https://doi.org/10.1371/journal.ppat.1001273.
    Full Text Link to Item
  - Weinberg, Adriana, Lin Ye Song, Cindy L. Wilkening, Terry Fenton, John Hural, Raul Louzao, Guido Ferrari, et al. “Optimization of storage and shipment of cryopreserved peripheral blood mononuclear cells from HIV-infected and uninfected individuals for ELISPOT assays..” J Immunol Methods 363, no. 1 (December 15, 2010): 42–50. https://doi.org/10.1016/j.jim.2010.09.032.
    Full Text Link to Item
  - Graham, Barney S., M Juliana McElrath, Michael C. Keefer, Kyle Rybczyk, David Berger, Kent J. Weinhold, Janet Ottinger, et al. “Immunization with cocktail of HIV-derived peptides in montanide ISA-51 is immunogenic, but causes sterile abscesses and unacceptable reactogenicity..” Plos One 5, no. 8 (August 10, 2010). https://doi.org/10.1371/journal.pone.0011995.
    Full Text Open Access Copy Link to Item
  - Freel, Stephanie A., Laurie Lamoreaux, Pratip K. Chattopadhyay, Kevin Saunders, David Zarkowsky, R Glenn Overman, Christina Ochsenbauer, et al. “Phenotypic and functional profile of HIV-inhibitory CD8 T cells elicited by natural infection and heterologous prime/boost vaccination..” J Virol 84, no. 10 (May 2010): 4998–5006. https://doi.org/10.1128/JVI.00138-10.
    Full Text Link to Item
  - Cella, Marina, Rachel Presti, William Vermi, Kerry Lavender, Emma Turnbull, Christina Ochsenbauer-Jambor, John C. Kappes, et al. “Loss of DNAM-1 contributes to CD8+ T-cell exhaustion in chronic HIV-1 infection..” European Journal of Immunology 40, no. 4 (April 2010): 949–54. https://doi.org/10.1002/eji.200940234.
    Full Text
  - Janetzki, Sylvia, L. Price, C. M. Britten, S. H. van der Burg, J. Caterini, J. R. Currier, G. Ferrari, et al. “Performance of serum-supplemented and serum-free media in IFNgamma Elispot Assays for human T cells..” Cancer Immunol Immunother 59, no. 4 (April 2010): 609–18. https://doi.org/10.1007/s00262-009-0788-2.
    Full Text Link to Item
  - Makedonas, George, Natalie Hutnick, Danielle Haney, Alexandra C. Amick, Jay Gardner, Gabriela Cosma, Adam R. Hersperger, et al. “Perforin and IL-2 upregulation define qualitative differences among highly functional virus-specific human CD8 T cells..” Plos Pathog 6, no. 3 (March 5, 2010). https://doi.org/10.1371/journal.ppat.1000798.
    Full Text Open Access Copy Link to Item
  - Goonetilleke, Nilu, Michael K. P. Liu, Jesus F. Salazar-Gonzalez, Guido Ferrari, Elena Giorgi, Vitaly V. Ganusov, Brandon F. Keele, et al. “The first T cell response to transmitted/founder virus contributes to the control of acute viremia in HIV-1 infection..” J Exp Med 206, no. 6 (June 8, 2009): 1253–72. https://doi.org/10.1084/jem.20090365.
    Full Text Link to Item
  - Lambotte, Olivier, Guido Ferrari, Christiane Moog, Nicole L. Yates, Hua-Xin Liao, Robert J. Parks, Charles B. Hicks, et al. “Heterogeneous neutralizing antibody and antibody-dependent cell cytotoxicity responses in HIV-1 elite controllers..” Aids 23, no. 8 (May 15, 2009): 897–906. https://doi.org/10.1097/QAD.0b013e328329f97d.
    Full Text Link to Item
  - Wood, Natasha, Tanmoy Bhattacharya, Brandon F. Keele, Elena Giorgi, Michael Liu, Brian Gaschen, Marcus Daniels, et al. “HIV evolution in early infection: selection pressures, patterns of insertion and deletion, and the impact of APOBEC..” Plos Pathog 5, no. 5 (May 2009). https://doi.org/10.1371/journal.ppat.1000414.
    Full Text Link to Item
  - Spearman, Paul, Spyros Kalams, Marnie Elizaga, Barbara Metch, Ya-Lin Chiu, Mary Allen, Kent J. Weinhold, et al. “Safety and immunogenicity of a CTL multiepitope peptide vaccine for HIV with or without GM-CSF in a phase I trial..” Vaccine 27, no. 2 (January 7, 2009): 243–49. https://doi.org/10.1016/j.vaccine.2008.10.051.
    Full Text Link to Item
  - Gasper-Smith, Nancy, Deanna M. Crossman, John F. Whitesides, Nadia Mensali, Janet S. Ottinger, Steven G. Plonk, M Anthony Moody, et al. “Induction of plasma (TRAIL), TNFR-2, Fas ligand, and plasma microparticles after human immunodeficiency virus type 1 (HIV-1) transmission: implications for HIV-1 vaccine design..” J Virol 82, no. 15 (August 2008): 7700–7710. https://doi.org/10.1128/JVI.00605-08.
    Full Text Link to Item
  - DREAM Trial Investigators, S., G. R. Dagenais, H. C. Gerstein, R. Holman, A. Budaj, A. Escalante, T. Hedner, et al. “Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trial..” Diabetes Care 31, no. 5 (May 2008): 1007–14. https://doi.org/10.2337/dc07-1868.
    Full Text Link to Item
  - Gorse, Geoffrey J., Lindsey R. Baden, Margaret Wecker, Mark J. Newman, Guido Ferrari, Kent J. Weinhold, Brian D. Livingston, et al. “Safety and immunogenicity of cytotoxic T-lymphocyte poly-epitope, DNA plasmid (EP HIV-1090) vaccine in healthy, human immunodeficiency virus type 1 (HIV-1)-uninfected adults..” Vaccine 26, no. 2 (January 10, 2008): 215–23. https://doi.org/10.1016/j.vaccine.2007.10.061.
    Full Text Link to Item
  - Montefiori, David C., Lynn Morris, Guido Ferrari, and John R. Mascola. “Neutralizing and other antiviral antibodies in HIV-1 infection and vaccination..” Curr Opin Hiv Aids 2, no. 3 (May 2007): 169–76. https://doi.org/10.1097/COH.0b013e3280ef691e.
    Full Text Link to Item
  - Russell, Nina D., Barney S. Graham, Michael C. Keefer, M Juliana McElrath, Steve G. Self, Kent J. Weinhold, David C. Montefiori, et al. “Phase 2 study of an HIV-1 canarypox vaccine (vCP1452) alone and in combination with rgp120: negative results fail to trigger a phase 3 correlates trial..” J Acquir Immune Defic Syndr 44, no. 2 (February 1, 2007): 203–12. https://doi.org/10.1097/01.qai.0000248356.48501.ff.
    Full Text Link to Item
  - Goepfert, Paul A., Georgia D. Tomaras, Helen Horton, David Montefiori, Guido Ferrari, Mark Deers, Gerald Voss, et al. “Durable HIV-1 antibody and T-cell responses elicited by an adjuvanted multi-protein recombinant vaccine in uninfected human volunteers..” Vaccine 25, no. 3 (January 5, 2007): 510–18. https://doi.org/10.1016/j.vaccine.2006.07.050.
    Full Text Link to Item
  - DREAM Trial Investigators, Rury R., Jackie Bosch, Salim Yusuf, Hertzel C. Gerstein, Janice Pogue, Patrick Sheridan, Gilles Dagenais, et al. “Effect of ramipril on the incidence of diabetes..” N Engl J Med 355, no. 15 (October 12, 2006): 1551–62. https://doi.org/10.1056/NEJMoa065061.
    Full Text Link to Item
  - Betts, Michael R., Clive M. Gray, Josephine H. Cox, and Guido Ferrari. “Antigen-specific T-cell-mediated immunity after HIV-1 infection: implications for vaccine control of HIV development..” Expert Rev Vaccines 5, no. 4 (August 2006): 505–16. https://doi.org/10.1586/14760584.5.4.505.
    Full Text Link to Item
  - Mulligan, M. J., N. D. Russell, C. Celum, J. Kahn, E. Noonan, D. C. Montefiori, G. Ferrari, et al. “Excellent safety and tolerability of the human immunodeficiency virus type 1 pGA2/JS2 plasmid DNA priming vector vaccine in HIV type 1 uninfected adults..” Aids Res Hum Retroviruses 22, no. 7 (July 2006): 678–83. https://doi.org/10.1089/aid.2006.22.678.
    Full Text Link to Item
  - Cox, Josephine H., Guido Ferrari, and Sylvia Janetzki. “Measurement of cytokine release at the single cell level using the ELISPOT assay..” Methods 38, no. 4 (April 2006): 274–82. https://doi.org/10.1016/j.ymeth.2005.11.006.
    Full Text Link to Item
  - Goepfert, Paul A., Helen Horton, M Juliana McElrath, Sanjay Gurunathan, Guido Ferrari, Georgia D. Tomaras, David C. Montefiori, et al. “High-dose recombinant Canarypox vaccine expressing HIV-1 protein, in seronegative human subjects..” J Infect Dis 192, no. 7 (October 1, 2005): 1249–59. https://doi.org/10.1086/432915.
    Full Text Link to Item
  - Sempowski, Gregory D., Charles B. Hicks, Joseph J. Eron, John A. Bartlett, Laura P. Hale, Guido Ferrari, Lloyd J. Edwards, Susan Fiscus, and Barton F. Haynes. “Naïve T cells are maintained in the periphery during the first 3 months of acute HIV-1 infection: implications for analysis of thymus function..” J Clin Immunol 25, no. 5 (September 2005): 462–72. https://doi.org/10.1007/s10875-005-5635-4.
    Full Text Link to Item
  - Betts, Michael R., Barbara Exley, David A. Price, Anju Bansal, Zenaido Tres Camacho, Vanessa Teaberry, Sadie M. West, et al. “Characterization of functional and phenotypic changes in anti-Gag vaccine-induced T cell responses and their role in protection after HIV-1 infection..” Proc Natl Acad Sci U S A 102, no. 12 (March 22, 2005): 4512–17. https://doi.org/10.1073/pnas.0408773102.
    Full Text Link to Item
  - Currier, Jeffrey R., Matthew E. Harris, Josephine H. Cox, Francine E. McCutchan, Deborah L. Birx, Shlomo Maayan, and Guido Ferrari. “Immunodominance and cross-reactivity of B5703-restricted CD8 T lymphocytes from HIV type 1 subtype C-infected Ethiopians..” Aids Res Hum Retroviruses 21, no. 3 (March 2005): 239–45. https://doi.org/10.1089/aid.2005.21.239.
    Full Text Link to Item
  - Cox, Josephine H., Guido Ferrari, Spyros A. Kalams, Wlodek Lopaczynski, Neal Oden, M Patricia D’souza, and M Patricia Elispot Collaborative Study Group. “Results of an ELISPOT proficiency panel conducted in 11 laboratories participating in international human immunodeficiency virus type 1 vaccine trials..” Aids Res Hum Retroviruses 21, no. 1 (January 2005): 68–81. https://doi.org/10.1089/aid.2005.21.68.
    Full Text Link to Item
  - Janetzki, Sylvia, Josephine H. Cox, Neal Oden, and Guido Ferrari. “Standardization and validation issues of the ELISPOT assay..” Methods Mol Biol 302 (2005): 51–86. https://doi.org/10.1385/1-59259-903-6:051.
    Full Text Link to Item
  - Kaplan, Susan S., Guido Ferrari, Terri Wrin, Nicholas S. Hellmann, Georgia D. Tomaras, Victoria E. Gryszowka, Susan A. Fiscus, Kent J. Weinhold, and Charles B. Hicks. “Longitudinal assessment of immune response and viral characteristics in HIV-infected patients with prolonged CD4(+)/viral load discordance..” Aids Res Hum Retroviruses 21, no. 1 (January 2005): 13–16. https://doi.org/10.1089/aid.2005.21.13.
    Full Text Link to Item
  - Ferrari, Guido, Wesley Neal, Janet Ottinger, Anizsa M. Jones, Bradley H. Edwards, Paul Goepfert, Michael R. Betts, et al. “Absence of immunodominant anti-Gag p17 (SL9) responses among Gag CTL-positive, HIV-uninfected vaccine recipients expressing the HLA-A*0201 allele..” J Immunol 173, no. 3 (August 1, 2004): 2126–33. https://doi.org/10.4049/jimmunol.173.3.2126.
    Full Text Link to Item
  - Ferrari, Guido, Jeffrey R. Currier, Matthew E. Harris, Stella Finkelstein, Angelica de Oliveira, Debra Barkhan, Josephine H. Cox, et al. “HLA-A and -B allele expression and ability to develop anti-Gag cross-clade responses in subtype C HIV-1-infected Ethiopians..” Hum Immunol 65, no. 6 (June 2004): 648–59. https://doi.org/10.1016/j.humimm.2004.02.031.
    Full Text Link to Item
  - Cox, J. H., G. Ferrari, R. T. Bailer, and R. A. Koup. “Automating Procedures for Processing, Cryopreservation, Storage, and Manipulation of Human Peripheral Blood Mononuclear Cells.” Journal of Laboratory Automation 9, no. 1 (January 1, 2004): 16–23. https://doi.org/10.1016/S1535-5535-03-00202-8.
    Full Text
  - Harris, Matthew E., Shlomo Maayan, Bohye Kim, Michael Zeira, Guido Ferrari, Deborah L. Birx, and Francine E. McCutchan. “A cluster of HIV type 1 subtype C sequences from Ethiopia, observed in full genome analysis, is not sustained in subgenomic regions..” Aids Res Hum Retroviruses 19, no. 12 (December 2003): 1125–33. https://doi.org/10.1089/088922203771881220.
    Full Text Link to Item
  - Sufka, Susan A., Guido Ferrari, Victoria E. Gryszowka, Terri Wrin, Susan A. Fiscus, Georgia D. Tomaras, Herman F. Staats, et al. “Prolonged CD4+ cell/virus load discordance during treatment with protease inhibitor-based highly active antiretroviral therapy: immune response and viral control..” J Infect Dis 187, no. 7 (April 1, 2003): 1027–37. https://doi.org/10.1086/368359.
    Full Text Link to Item
  - Currier, Jeffrey R., Ellen G. Kuta, Ellen Turk, Lyndsay B. Earhart, Larry Loomis-Price, Sylvia Janetzki, Guido Ferrari, Deborah L. Birx, and Josephine H. Cox. “A panel of MHC class I restricted viral peptides for use as a quality control for vaccine trial ELISPOT assays..” J Immunol Methods 260, no. 1–2 (February 1, 2002): 157–72.
    Link to Item
  - Ferrari, G., W. Neal, A. Jones, N. Olender, J. Ottinger, R. Ha, M. J. McElrath, P. Goepfert, and K. J. Weinhold. “CD8 CTL responses in vaccines: emerging patterns of HLA restriction and epitope recognition..” Immunol Lett 79, no. 1–2 (November 1, 2001): 37–45.
    Link to Item
  - Ferrari, G., D. D. Kostyu, J. Cox, D. V. Dawson, J. Flores, K. J. Weinhold, and S. Osmanov. “Identification of highly conserved and broadly cross-reactive HIV type 1 cytotoxic T lymphocyte epitopes as candidate immunogens for inclusion in Mycobacterium bovis BCG-vectored HIV vaccines..” Aids Res Hum Retroviruses 16, no. 14 (September 20, 2000): 1433–43. https://doi.org/10.1089/08892220050140982.
    Full Text Link to Item
  - Tomaras, G. D., S. F. Lacey, C. B. McDanal, G. Ferrari, K. J. Weinhold, and M. L. Greenberg. “CD8+ T cell-mediated suppressive activity inhibits HIV-1 after virus entry with kinetics indicating effects on virus gene expression..” Proc Natl Acad Sci U S A 97, no. 7 (March 28, 2000): 3503–8. https://doi.org/10.1073/pnas.070521097.
    Full Text Link to Item
  - Markert, M. L., C. B. Hicks, J. A. Bartlett, J. L. Harmon, L. P. Hale, M. L. Greenberg, G. Ferrari, et al. “Effect of highly active antiretroviral therapy and thymic transplantation on immunoreconstitution in HIV infection..” Aids Res Hum Retroviruses 16, no. 5 (March 20, 2000): 403–13. https://doi.org/10.1089/088922200309061.
    Full Text Link to Item
  - Falk, Lydia A., Karen L. Goldenthal, Jose Esparza, M Teresa Aguado, Saladin Osmanov, and W Ripley Ballou. “Recombinant Bacillus Calmette-Guerin as a Potential Vector for Preventive HIV Type 1 Vaccines.” Aids Research and Human Retroviruses 16, no. 2 (January 20, 2000): 91–98. https://doi.org/10.1089/088922200309421.
    Full Text
  - Stranford, S. A., J. Skurnick, D. Louria, D. Osmond, S. Y. Chang, J. Sninsky, G. Ferrari, K. Weinhold, C. Lindquist, and J. A. Levy. “Lack of infection in HIV-exposed individuals is associated with a strong CD8(+) cell noncytotoxic anti-HIV response..” Proc Natl Acad Sci U S A 96, no. 3 (February 2, 1999): 1030–35. https://doi.org/10.1073/pnas.96.3.1030.
    Full Text Link to Item
  - Ferrari, G., C. Berend, J. Ottinger, R. Dodge, J. Bartlett, J. Toso, D. Moody, et al. “Replication-defective canarypox (ALVAC) vectors effectively activate anti-human immunodeficiency virus-1 cytotoxic T lymphocytes present in infected patients: implications for antigen-specific immunotherapy..” Blood 90, no. 6 (September 15, 1997): 2406–16.
    Link to Item
  - Ferrari, G., W. Humphrey, M. J. McElrath, J. L. Excler, A. M. Duliege, M. L. Clements, L. C. Corey, D. P. Bolognesi, and K. J. Weinhold. “Clade B-based HIV-1 vaccines elicit cross-clade cytotoxic T lymphocyte reactivities in uninfected volunteers..” Proc Natl Acad Sci U S A 94, no. 4 (February 18, 1997): 1396–1401. https://doi.org/10.1073/pnas.94.4.1396.
    Full Text Link to Item
  - Toso, J. F., C. H. Chen, J. R. Mohr, L. Piglia, C. Oei, G. Ferrari, M. L. Greenberg, and K. J. Weinhold. “Oligoclonal CD8 lymphocytes from persons with asymptomatic human immunodeficiency virus (HIV) type 1 infection inhibit HIV-1 replication..” J Infect Dis 172, no. 4 (October 1995): 964–73. https://doi.org/10.1093/infdis/172.4.964.
    Full Text Link to Item
  - Ferrari, G., K. King, K. Rathbun, C. A. Place, M. V. Packard, J. A. Bartlett, D. P. Bolognesi, and K. J. Weinhold. “IL-7 enhancement of antigen-driven activation/expansion of HIV-1-specific cytotoxic T lymphocyte precursors (CTLp)..” Clin Exp Immunol 101, no. 2 (August 1995): 239–48. https://doi.org/10.1111/j.1365-2249.1995.tb08345.x.
    Full Text Link to Item
  - Ferrari, G., C. A. Place, P. M. Ahearne, S. M. Nigida, L. O. Arthur, D. P. Bolognesi, and K. J. Weinhold. “Comparison of anti-HIV-1 ADCC reactivities in infected humans and chimpanzees..” J Acquir Immune Defic Syndr 7, no. 4 (April 1994): 325–31.
    Link to Item
  - Ferrari, G., J. Ottinger, C. Place, S. M. Nigida, L. O. Arthur, and K. J. Weinhold. “The impact of HIV-1 infection on phenotypic and functional parameters of cellular immunity in chimpanzees..” Aids Res Hum Retroviruses 9, no. 7 (July 1993): 647–56. https://doi.org/10.1089/aid.1993.9.647.
    Full Text Link to Item
  - BOERI, E., A. GIRI, F. LILLO, G. FERRARI, O. E. VARNIER, A. FERRO, S. SABBATANI, W. C. SAXINGER, and G. FRANCHINI. “INVIVO GENETIC-VARIABILITY OF THE HUMAN-IMMUNODEFICIENCY-VIRUS TYPE-2 V3-REGION.” Journal of Virology 66, no. 7 (July 1, 1992): 4546–50.
    Link to Item
  - Boeri, E., A. Giri, F. Lillo, G. Ferrari, O. E. Varnier, A. Ferro, S. Sabbatani, W. C. Saxinger, and G. Franchini. “In vivo genetic variability of the human immunodeficiency virus type 2 V3 region..” J Virol 66, no. 7 (July 1992): 4546–50.
    Link to Item
  - CANESSA, A., F. PANTAROTTO, F. MILETICH, A. RUSSO, C. GOTTA, P. M. BOZZUFFI, G. FERRARI, A. FIORELLI, and A. TERRAGNA. “ANTIBODY PREVALENCE TO TORCH AGENTS IN PREGNANT-WOMEN AND RELATIVE RISK OF CONGENITAL INFECTIONS IN ITALY (LIGURIA).” Biological Research in Pregnancy and Perinatology 8, no. 2 (January 1, 1987): 84–88.
    Link to Item
  - Canessa, A., F. Pantarotto, F. Miletich, A. Russo, C. Gotta, P. M. Bozzuffi, G. Ferrari, A. Fiorelli, and A. Terragna. “Antibody prevalence to torch agents in pregnant women and relative risk of congenital infections in Italy (Liguria)..” Biol Res Pregnancy Perinatol 8, no. 2 2D Half (1987): 84–88.
    Link to Item
  - Mimano, L. N., G. Ferrari, G. Kapanda, E. Lisasi, A. Kulanga, B. Nyombi, C. Muiruri, E. Kessi, J. Bartlett, and M. Ntabaye. “Student perceptions on the introduction of training in diagnostic laboratory techniques in an African school of medicine.” Mededpublish, n.d. https://doi.org/10.15694/mep.2015.005.0008.
    Full Text
- Book Sections
  - D’Souza, P., J. H. Cox, G. Ferrari, N. T. Kunwar, V. Polonis, and M. Sarzotti-Kelsoe. “Endpoint Assays in HIV-1 Vaccine Trials: Functioning in a Good Laboratory Practices Environment.” In Validation of Cell-Based Assays in the GLP Setting: A Practical Guide, 239–75, 2008. https://doi.org/10.1002/9780470987810.ch14.
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- Other Articles
  - Kvistborg, Pia, Cécile Gouttefangeas, Nima Aghaeepour, Angelica Cazaly, Pratip K. Chattopadhyay, Cliburn Chan, Judith Eckl, et al. “Thinking outside the gate: single-cell assessments in multiple dimensions..” Immunity, April 21, 2015. https://doi.org/10.1016/j.immuni.2015.04.006.
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  - Frahm, M. A., G. D. Tomaras, and G. Ferrari. “Response to comment on "CD4 ⁺CD8 ⁺ T cells represent a significant portion of the anti-HIV T cell response to acute HIV infection".” Journal of Immunology, June 15, 2012. https://doi.org/10.4049/jimmunol.1290029.
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  - “Approaches to the development of broadly protective HIV vaccines: challenges posed by the genetic, biological and antigenic variability of HIV-1: Report from a meeting of the WHO-UNAIDS Vaccine Advisory Committee Geneva, 21-23 February 2000..” Aids, April 13, 2001.
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  - Rodenburg, C. M., Y. Li, S. A. Trask, Y. Chen, J. Decker, D. L. Robertson, M. L. Kalish, et al. “Near full-length clones and reference sequences for subtype C isolates of HIV type 1 from three different continents..” Aids Res Hum Retroviruses, January 20, 2001. https://doi.org/10.1089/08892220150217247.
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- Conference Papers
  - Asbach, Benedikt, Karen V. Kibler, Josef Köstler, Beatriz Perdiguero, Nicole L. Yates, Sherry Stanfield-Oakley, Georgia D. Tomaras, et al. “Priming with a Potent HIV-1 DNA Vaccine Frames the Quality of Immune Responses prior to a Poxvirus and Protein Boost..” In J Virol, Vol. 93, 2019. https://doi.org/10.1128/JVI.01529-18.
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  - Felber, Barbara, Shakti Singh, Antonio Valentin, Margherita Rosati, Eric Ramierz, Rami Doueiri, Xintao Hu, et al. “DNA and protein co-delivery vaccines using TLR-4-based adjuvants induce potent immune responses able to delay heterologous SIV acquisition.” In Journal of Medical Primatology, 47:313–313. WILEY, 2018.
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  - Mielke, Dieter, Rutendo Ziki, Colin Anthony, Christina Ochsenbauer, Nigel Garrett, Salim S Abdool Karim, David Montefiori, et al. “Neutralizing and ADCC Activity of Anti-HIV-1 Antibodies Against Acute Subtype C Envs: Implications for Prevention and Treatment of HIV-1 Infection.” In Aids Research and Human Retroviruses, 34:53–53. MARY ANN LIEBERT, INC, 2018.
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  - Msafiri, Frank, Agricola Joachim, Raquel Matavele Chissumba, Christof Geldmacher, Said Aboud, Wolfgang Stohr, Edna Viegas, et al. “Frequent Anti-V1V2 Responses Induced by HIV-DNA Followed by HIV-MVA With or Without CN54rgp140/GLA-AF in Healthy Tanzanian and Mozambican Volunteers.” In Aids Research and Human Retroviruses, 34:119–20. MARY ANN LIEBERT, INC, 2018.
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  - Phillips, Bonnie, Genevieve Fouda, Justin Pollara, Pamela Kozlowski, Anthony Moody, Guido Ferrari, Sallie Permar, and Kristina De Parisi. “The optimization of pediatric vaccine regimens to prevent mother-to-child transmission of HIV through breast milk.” In Journal of Medical Primatology, 47:344–45. WILEY, 2018.
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  - Pollara, Justin, Dorothy I. Jones, Tori Huffman, Maria Dennis, Grace Li, Derrick Goodman, R Whitney Edwards, et al. “Bridging Vaccine-induced Antibody Responses in Rabbit and Rhesus Macaque Animal Models.” In Aids Research and Human Retroviruses, 34:129–129. MARY ANN LIEBERT, INC, 2018.
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  - Shen, Xiaoying, Zoe Moodie, Arthur McMillan, Derrick Goodman, Nicole Yates, Rachel Spreng, Nicole Grunenberg, et al. “V1V2 IgG and Antibody Fc Effector Functions in a Subtype C ALVAC-HIV and Bivalent Subtype C gp120/MF59 HIV-1 Vaccine Trial in South Africa.” In Aids Research and Human Retroviruses, 34:17–17. MARY ANN LIEBERT, INC, 2018.
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  - Tuyishime, Marina, Carolina Garrido, Shalini Jha, Anthony DeVico, Barton Haynes, David Margolis, and Guido Ferrari. “Recognition and Elimination of HIV-1-infected Cells by ADCC-mediating mAbs for Prevention and Treatment of HIV-1 Infection.” In Aids Research and Human Retroviruses, 34:126–126. MARY ANN LIEBERT, INC, 2018.
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  - Wang, Shixia, Justin Pollara, Sherry Stanfield-Oakley, Diego Farfan-Arribas, Shuying Liu, Guido Ferrari, and Shan Lu. “Cross-clade ADCC Activities in Human Volunteer Sera Elicited by a Polyvalent DNA Prime-protein Boost HIV Vaccine DP6-001.” In Aids Research and Human Retroviruses, 34:129–129. MARY ANN LIEBERT, INC, 2018.
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  - Williams, LaTonya, Matthew Zirui Tay, Xiaoying Shen, Sheetal Sawant, Lindsay Dahora, Nicole Yates, David Easterhoff, et al. “Delayed and Repetitive Boosting of RV144 Vaccinees Improves Antiviral Immunity Associated With Correlates of HIV-1 Infection Risk.” In Aids Research and Human Retroviruses, 34:88–88. MARY ANN LIEBERT, INC, 2018.
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  - Ferrari, Guido, Jeffrey Nordstrom, Scott Koenig, Julia Sung, David Margolis, and Barton Haynes. “A-102 Antibody binding to HIV-1 infected cells as mechanism for treatment of HIV infection.” In Jaids Journal of Acquired Immune Deficiency Syndromes, 77:33–33. Ovid Technologies (Wolters Kluwer Health), 2018. https://doi.org/10.1097/01.qai.0000532483.69631.d6.
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  - Buchbinder, Susan, Nicole Grunenberg, Brittany Sanchez, Kelly Seaton, Guido Ferrari, M Anthony Moody, Nicole Frahm, et al. “DNA/MVA HIV Vaccine Producing Virus-like Particles (VLPs) Is Well-tolerated and Induces Durable Functional Antibodies (Abs) in HVTN 094.” In Aids Research and Human Retroviruses, 32:99–99. MARY ANN LIEBERT, INC, 2016.
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  - Huang, Ying, Georgia Tomaras, Erica Andersen-Nissen, One Dintwe, Lynn Morris, Nicole Grunenberg, Abby Issacs, et al. “The Relationship between Immune Responses to Tetanus Vaccine, Hepatitis B Vaccine and a Pox-protein HIV Vaccine Regimen.” In Aids Research and Human Retroviruses, 32:76–76. MARY ANN LIEBERT, INC, 2016.
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  - Shen, Xiaoying, Rahul Basu, Suefen Kwa, Celia Labranche, David Beaumont, Guido Ferrari, Linda Wyatt, et al. “MVA-expressed gp140 Boosts More Durable V1/V2 and gp120 Antibody Responses than gp120 Protein in Alum.” In Aids Research and Human Retroviruses, 32:59–59. MARY ANN LIEBERT, INC, 2016.
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  - Clutton, Genevieve Tyndale, Yinyan Xu, Maria Abad Fernandez, Amanda Crooks, Blair Turner, Nicole Maponga, Anna Cope, et al. “Effects of different treatment regimens on T cell function in acute HIV infection.” In Journal of Immunology, Vol. 196. AMER ASSOC IMMUNOLOGISTS, 2016.
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  - Prentice, Heather, Georgia Tomaras, Daniel Geraghty, Richard Apps, Youyi Fong, Philip Ehrenberg, Morgane Rolland, et al. “HIV-1-specific IgG antibody levels correlate with the presence of a specific HLA class II allele to impact acquisition and vaccine efficacy.” In Journal of the International Aids Society, Vol. 18. INT AIDS SOCIETY, 2015. https://doi.org/10.7448/IAS.18.5.20541.
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  - Swiderska-Syn, M., S. Choi, A. Lan, G. Ferrari, A. M. Diehl, and S. Naggie. “P0469 : Markers of tissue repair and cellular aging are increased in liver tissue of patients with dual chronic HIV/HCV infections.” In Journal of Hepatology, 62:S489–S489. Elsevier BV, 2015. https://doi.org/10.1016/s0168-8278(15)30677-2.
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  - Fouda, G., J. Pollara, E. McGuire, W. Rountree, G. Overman, G. Tegha, D. Kamwendo, et al. “Association of HIV-1 Env Antibody Responses with Postnatal Mother-to-Child Transmission of HIV-1 via Breastfeeding..” In Aids Res Hum Retroviruses, 30 Suppl 1:A99–100, 2014. https://doi.org/10.1089/aid.2014.5182c.abstract.
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  - Fourati, S., M. Vaccari, S. N. Gordon, L. Schifanella, M. Cameron, B. F. Keele, X. Shen, et al. “Modulation of RAS Pathways as a Biomarker of Protection against HIV and as a Means to Improve Vaccine Efficacy..” In Aids Res Hum Retroviruses, Vol. 30 Suppl 1, 2014. https://doi.org/10.1089/aid.2014.5182b.abstract.
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  - Moody, M. A., D. Easterhoff, T. C. Gurley, J. F. Whitesides, D. J. Marshall, A. Foulger, K. E. Lloyd, et al. “Induction of Antibodies with Long Variable Heavy Third Complementarity Determining Regions by Repetitive Boosting with AIDSVAX® B/E in RV144 Vaccinees..” In Aids Res Hum Retroviruses, Vol. 30 Suppl 1, 2014. https://doi.org/10.1089/aid.2014.5057a.abstract.
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  - Vaccari, M., S. N. Gordon, S. Fourati, L. Schifanella, M. Cameron, B. F. Keele, X. Shen, et al. “Adjuvant Dependent Mucosal V2 Responses and RAS Activation in Vaccine Induced Protection from SIVmac251 Acquisition..” In Aids Res Hum Retroviruses, 30 Suppl 1:A64–65, 2014. https://doi.org/10.1089/aid.2014.5117.abstract.
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  - Ackerman, M. E., Y. Huang, G. Alter, G. Ferrari, D. Forthal, J. Kappes, G. Lewis, et al. “Comparative Evaluation of Assays for Fc Receptor-Mediated Antibody Effector Functions Targeting HIV-1.” In Aids Research and Human Retroviruses, 29:A169–A169. MARY ANN LIEBERT, INC, 2013.
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  - Blasi, M., D. Negri, S. Santra, R. Parks, X. Shen, G. Tomaras, S. Permar, et al. “A Single Immunization with Integrase Defective Lentiviral Vector Expressing gp140 Induces Persistent and Functional Immune Response in Rhesus Monkeys.” In Aids Research and Human Retroviruses, 29:A161–A161. MARY ANN LIEBERT, INC, 2013.
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  - Chege, G. K., D. C. Montefiori, S. Barnett, C. M. Gray, W. A. Burgers, T. L. Muller, E. G. Shephard, C. Williamson, G. Ferrari, and A. Williamson. “A Combined Saavi MVA-C and Novartis Gp140 Env Protein Vaccine Boost Elicits Robust HIV Cellular and Humoral Responses in a Nonhuman Primate Model.” In Aids Research and Human Retroviruses, 29:A39–A39. MARY ANN LIEBERT, INC, 2013.
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  - Gao, F., M. Bonsignori, H. Liao, A. Kumar, S. Xia, F. Cai, X. Lu, et al. “Multiple Pathways of HIV-1 Autologous Neutralizing Antibodies Cooperate to Drive CD4 Binding Site Broadly Neutralizing Antibody Responses.” In Aids Research and Human Retroviruses, 29:A186–A186. MARY ANN LIEBERT, INC, 2013.
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  - Gordon, S. N., M. Vaccari, M. N. Doster, N. P. Liyanage, P. Pegu, L. Schifanella, F. Caccuri, et al. “Priming with Adenovirus26 Vaccines Affects ALVAC-SIV/gp120 Vaccine Efficacy Tested in a SIVmac251 Challenge Model Performed One-Month Post-Vaccination.” In Aids Research and Human Retroviruses, 29:A39–A39. MARY ANN LIEBERT, INC, 2013.
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  - Joachim, A., P. Munseri, C. Nilsson, M. Bakari, S. Aboud, E. F. Lyamuya, C. Moshiro, et al. “A Late Third HIV-MVA Vaccination Boosted Strong and Potent Immune Responses in Tanzanian Volunteers Previously Immunized with HIV-DNA and HIV-MVA.” In Aids Research and Human Retroviruses, 29:A174–A174. MARY ANN LIEBERT, INC, 2013.
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  - Li, S. S., P. B. Gilbert, G. D. Tomaras, G. Kijak, G. Ferrari, R. Thomas, S. Zolla-Pazner, et al. “Association of Fc gamma RIIC Polymorphism with Vaccine Efficacy and Correlates of HIV-1 Infection Risk in RV144.” In Aids Research and Human Retroviruses, 29:A178–79. MARY ANN LIEBERT, INC, 2013.
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  - Pollara, J., M. Bonsignori, M. Moody, S. Alam, K. Hwang, T. C. Gurley, D. M. Kozink, et al. “Heterogeneity of Anti-V2 ADCC Ab Responses and Implications for Vaccine Development.” In Aids Research and Human Retroviruses, 29:A41–A41. MARY ANN LIEBERT, INC, 2013.
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  - Schifanella, L., S. Gordon, M. Vaccari, N. Binello, F. Caccuri, M. Blackburn, C. Fenizia, et al. “MF59 and ALUM, in Combination with an ALVAC-SIV/gp120 Vaccine, Induce Plasmablasts that Differ in the Expression of Homing Markers.” In Aids Research and Human Retroviruses, 29:A13–A13. MARY ANN LIEBERT, INC, 2013.
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  - Vaccari, M., S. N. Gordon, M. Doster, N. Liynage, P. Pegu, L. Schifanella, B. F. Keele, et al. “Protection from SIVmac251 Acquisition by an ALVAC/SIV/gp120 Regimen Is Not Improved by the Increase of Anti-Envelope Antibodies and T Cell Responses.” In Aids Research and Human Retroviruses, 29:A34–A34. MARY ANN LIEBERT, INC, 2013.
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  - Wise, M., N. Hutnick, J. Pollara, D. Myles, A. Khan, S. Barnette, G. Ferrari, D. Montefiori, N. Sardesai, and D. Weiner. “Multiclade E-DNA Prime Enhances the Functional Antibody Response Induced by a Recombinant gp120 Boost in Non-human Primates.” In Aids Research and Human Retroviruses, 29:A38–A38. MARY ANN LIEBERT, INC, 2013.
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  - Bonsignori, M., J. Pollara, M. A. Moody, T. B. Kepler, X. Chen, T. C. Gurley, D. M. Kozink, et al. “Antibody-dependent cellular cytotoxicity-mediating antibodies from an HIV-1 vaccine efficacy trial preferentially use the VH1 gene family.” In Retrovirology, Vol. 9. Springer Nature, 2012. https://doi.org/10.1186/1742-4690-9-s2-p78.
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  - Franchini, G., P. Pegu, S. Gordon, B. Keele, M. Doster, Y. Guan, G. Ferrari, et al. “Antibodies to the envelope protein protect macaques from SIVmac251 acquisition in an immunization regimen that mimics the RV-144 Thai trial.” In Retrovirology, Vol. 9. Springer Nature, 2012. https://doi.org/10.1186/1742-4690-9-s2-o2.
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  - Joachim, A., C. Nilsson, S. Aboud, E. F. Lyamuya, M. Robb, M. Marovich, C. Ochsenbauer, et al. “Antibody-mediated inhibition of HIV-1 elicited by HIV-I DNA priming and boosting with heterologous HIV-1 recombinant MVA in healthy Tanzanian adults.” In Retrovirology, Vol. 9. Springer Nature, 2012. https://doi.org/10.1186/1742-4690-9-s2-o53.
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  - Pollara, J., M. Bonsignori, M. Moody, M. Alam, H. Liao, K. Hwang, J. Pickeral, et al. “Vaccine-induced ADCC-mediating antibodies target unique and overlapping envelope epitopes.” In Retrovirology, Vol. 9. Springer Nature, 2012. https://doi.org/10.1186/1742-4690-9-s2-o39.
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  - Williams, W. B., K. Jones, A. Krambrink, D. Grove, P. Liu, N. L. Yates, M. A. Moody, et al. “Multiple antibody specificities (gp41, V1V2, and V3) elicited in the phase II multiclade (A, B, C) HIV-1 DNA prime, rAd5 boost vaccine trial.” In Retrovirology, Vol. 9. Springer Nature, 2012. https://doi.org/10.1186/1742-4690-9-s2-o55.
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  - Hutnick, N. A., M. Karuppiah, J. Pollara, J. Yan, D. J. Myles, K. Broderick, M. Morrow, et al. “E-DNA IM or ID delivery prime enhances antibody and T cell responses following recombinant gp120 env boost.” In Retrovirology, 9:P364–P364. Springer Nature, 2012. https://doi.org/10.1186/1742-4690-9-s2-p364.
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  - Ferrari, G., J. Cox, A. Garcia, W. Rountree, C. DeCastro, R. Louzao, B. Liebl, et al. “Development of CAVD/EQAPOL Long-Term PBMC Repository ('07-'10) @ DUMC; T-Cell Functionality as Measured by ELISpot and Flow Cytometry Is Maintained Ov.” In Aids Research and Human Retroviruses, 27:A55–A55. MARY ANN LIEBERT INC, 2011.
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  - Ferrari, G., J. Pollara, D. Kozink, T. Harms, M. Drinker, S. Freel, M. A. Moody, et al. “Mapping of ADCC Activity: The A32 Conformational C1 Epitope is a Dominant Target for ADCC Antibodies in Chronically HIV-1 Infected Subjects.” In Aids Research and Human Retroviruses, 27:A66–A66. MARY ANN LIEBERT INC, 2011.
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  - Fouda, G., N. Yates, J. Pollara, G. Overman, T. Mahlokozera, A. Wilks, H. Kang, et al. “HIV Neutralization in Breast Milk Mirrors that of Plasma and Is Mainly Mediated by IgG Antibodies.” In Aids Research and Human Retroviruses, 27:A72–A72. MARY ANN LIEBERT INC, 2011.
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  - Franchini, G., M. Vaccari, B. Keele, M. Doster, Z. Ma, A. Hryniewicz, T. Morgan, et al. “Efficacy of HIV Vaccine Candidate in Macaques Dependent on the Dose of SIVmac251 Challenge Exposure: Immune Correlates of Vaccine Efficacy.” In Aids Research and Human Retroviruses, 27:A111–A111. MARY ANN LIEBERT INC, 2011.
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  - Franchini, G., P. Pegu, M. Vaccari, S. Gordon, B. Keele, M. Doster, Y. Guan, et al. “Titered Mucosal Challenge of Rhesus Macaques with SIVmac251 Recapitulates HIV Vaccine Efficacy in Humans.” In Aids Research and Human Retroviruses, 27:A4–A4. MARY ANN LIEBERT INC, 2011.
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  - Freel, S. A., R. A. Picking, G. Ferrari, C. Ochsenbauer, J. C. Kappes, J. Kirchherr, K. J. Weinhold, et al. “Ontogeny of CD8+T Cells in Acute HIV-1 that Inhibit Autologous and Heterologous Transmitted/Founder (T/F) Viruses.” In Aids Research and Human Retroviruses, 27:A13–A13. MARY ANN LIEBERT INC, 2011.
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  - Pollara, J., L. Morris, N. Meguid, J. Pickeral, J. Hoxie, J. Kappes, C. Ochsenbauer, et al. “Ontogeny, Breadth, and Specificity of Circulating ADCC-Mediating Antibodies in HIV-1 Infected Individuals.” In Aids Research and Human Retroviruses, 27:A66–67. MARY ANN LIEBERT INC, 2011.
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  - Ferrari, G., B. Korber, E. Turnbull, M. K. Liu, N. Goonetilleke, J. Salazar, M. Betts, et al. “High magnitude and multifunctionality epitope-specific CD8+T-cell responses are associated are associated with selection of escape mutants in acute HIV infection.” In Aids Research and Human Retroviruses, 26:A5–6. MARY ANN LIEBERT INC, 2010.
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  - Pollara, J., G. Landucci, C. Trac, C. White, N. Yates, J. Kappes, C. Ochsenbauer, et al. “Early Appearance of ADCC- and ADCVI-mediating Antibody Responses Against Autologous HIV-1 Transmitted/Founder Virus.” In Aids Research and Human Retroviruses, 26:A12–A12. MARY ANN LIEBERT INC, 2010.
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  - Pollara, J., L. Hart, J. Hoxie, J. Kappes, C. Ochsenbauer, L. Morris, K. Soderberg, et al. “High titers of cross-clade ADCC-mediating antibodies are detectable in plasma samples collected from individuals with broadly neutralizing antibodies.” In Aids Research and Human Retroviruses, 26:A20–21. MARY ANN LIEBERT INC, 2010.
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  - Yates, N., X. Shen, P. Liu, S. Barnett, P. Spearman, S. Lu, G. Ferrari, et al. “Vaccine-Elicited IgG Subclasses and Functional Antibodies.” In Aids Research and Human Retroviruses, 26:A157–A157. MARY ANN LIEBERT INC, 2010.
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  - Cristillo, A. D., G. Ferrari, L. Hudacik, D. Thompson, B. Bowen, B. Lewis, L. Galmin, et al. “P11-21. Induction of persistent mucosal humoral and cellular responses following immunization of mice with HIV-1 envelope protein in inulin-derived adjuvants..” In Retrovirology, 6:P166–P166, 2009. https://doi.org/10.1186/1742-4690-6-S3-P166.
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  - Ferrari, G., A. Garcia-Louzao, J. Cox, A. Sambor, P. D’Souza, C. Gray, M. Jaimes, et al. “Establishing PBMC Repository for T Cell Assays Optimization and Proficiency Testing in CTC-VIMC Laboratories.” In Aids Research and Human Retroviruses, 24:127–28. MARY ANN LIEBERT INC, 2008.
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  - Ferrari, G., M. Liu, C. Marking, N. Goonetilleke, M. Betts, C. Gray, B. Haynes, A. McMichael, and K. Weinhold. “Lack of Highly Poly-Functional Epitope-Specific CD8+Memory T Cell Responses during Spontaneous Control of Viremia.” In Aids Research and Human Retroviruses, 24:20–20. MARY ANN LIEBERT INC, 2008.
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  - Liu, M. K., G. Ferrari, J. Salazar, B. Keele, R. L. Tanner, E. Turnbull, M. Mlotshwa, et al. “T Cell Escape in Subjects with Acute HIV-1 Infection.” In Aids Research and Human Retroviruses, 24:6–7. MARY ANN LIEBERT INC, 2008.
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  - Sichangi, M. W., J. Bartlett, G. Ferrari, J. Crump, A. Muisyo, J. Puleo, T. Moody, B. Haynes, and J. Shao. “Detection of Cross-Clade T- and B-Cell-Mediated Immune Responses among HIV-1 Infected Individuals in Northern Tanzania.” In Aids Research and Human Retroviruses, 24:92–92. MARY ANN LIEBERT INC, 2008.
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  - Lathey, Janet, Neal Oden, Scott Gregory, Josephine Cox, Guido Ferrari, Susan Zimmermann, Richard Koup, M. Patricia D’Souza, and Isaac Rodriguez-Chavez. “Sa.133. ELISpot Proficiency Testing for International Laboratories Participating in HIV Vaccine Trials.” In Clinical Immunology, 119:S152–S152. Elsevier BV, 2006. https://doi.org/10.1016/j.clim.2006.04.365.
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  - Sempowski, G. D., C. Hicks, L. Edwards, G. Ferrari, J. Eron, and B. F. Haynes. “Naive T cells are maintained in the periphery during acute HIV infection..” In Faseb Journal, 16:A297–A297. FEDERATION AMER SOC EXP BIOL, 2002.
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  - Demarest, J. F., S. B. Jones, G. Ferrari, C. J. Johnson, M. Greenberg, T. O. O’Brien, W. Blattner, et al. “Natural history of HIV-specific CTL activity during acute HIV infection: envelope CTL impact subsequent plasma viremia..” In Faseb Journal, 13:A294–A294. FEDERATION AMER SOC EXP BIOL, 1999.
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  - Stranford, S., J. Skurnick, D. Louria, D. Osmond, S. Y. Chang, J. Sninsky, G. Ferrari, K. Weinhold, C. Lindquist, and J. Levy. “The CD8+ cell non-cytotoxic, anti-HIV response is associated with protection in HIV-exposed, uninfected individuals.” In Faseb Journal, Vol. 12, 1998.
  - Weinhold, K. J., W. Humphrey, K. Corr, J. Johnson, M. West, C. Wiggins, S. Jones, J. Ottinger, M. Blanks, and G. Ferrari. “Cellular immune responses to candidate AIDS vaccines.” In 11e Colloque Des Cent Gardes, edited by M. Girard and B. Dodet, 167–75. EDITIONS SCIENTIFIQUES ET MEDICALES ELSEVIER, 1998.
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  - Laughlin, M. J., J. Kurtzberg, K. Weinhold, G. Ferrari, A. Pilgrim, C. Gelber, S. Nair, et al. “Generation of T lymphocyte clones specific for acute lymphoblastic leukemia (ALL) via dendritic cell (DC) presentation..” In Blood, 88:1487–1487. W B SAUNDERS CO, 1996.
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  - FERRARI, G., C. PLACE, J. BARTLETT, D. MOODY, J. TARTAGLIA, E. PAOLETTI, and K. WEINHOLD. “ANTIGEN-SPECIFIC ACTIVATION/EXPANSION OF HUMAN ANTI-HIV CTL USING RECOMBINANT ALVAC (CANARYPOX)-BASED VECTORS.” In Journal of Cellular Biochemistry, 219–219. WILEY-LISS, 1995.
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  - FERRARI, G., K. KING, M. PACKARD, J. A. BARTLETT, J. TARTAGLIA, J. TOSO, and K. J. WEINHOLD. “THE EFFECT OF INTERLEUKIN-7 ON FUNCTIONAL AND PHENOTYPIC PROPERTIES OF ANTIGEN-DRIVEN CTL.” In Journal of Cellular Biochemistry, 354–354. WILEY-LISS, 1994.
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  - WEINHOLD, K. J., K. T. RATHBUN, C. A. PLACE, G. FERRARI, and D. P. BOLOGNESI. “CYTOTOXIC T-LYMPHOCYTE REACTIVITIES AMONG HIV-1 VACCINE RECIPIENTS IN THE AIDS VACCINE EVALUATION NETWORK.” In Aids Research and Human Retroviruses, 10:S89–S89. MARY ANN LIEBERT INC PUBL, 1994.
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  - FERRARI, G., M. V. PACKARD, J. A. BARTLETT, and K. J. WEINHOLD. “TH1 AND TH2 CD4 SUBSET RESPONSES IN HIV-1 INFECTED INDIVIDUALS AT VARIOUS STAGES OF DISEASE.” In Journal of Cellular Biochemistry, 78–78. WILEY-LISS, 1993.
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  - WEINHOLD, K. J., G. FERRARI, and L. O. ARTHUR. “COMPARISON OF CELLULAR ANTIVIRAL CYTOTOXICITIES PRESENT IN HIV-1 INFECTED HUMANS AND CHIMPANZEES.” In Aids Research and Human Retroviruses, 8:938–938. MARY ANN LIEBERT INC PUBL, 1992.
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Teaching & Mentoring
Recent Courses
Advising & Mentoring
- I have been involved in teaching and training new researchers in several capacities. Since 2001, as part of consulting work for the World Health Organization and United Nation AIDS program (WHO/UNAIDS), I have organized and taught in 8 international ELISpot and Flow Cytometry workshops in South America (1), Asia (1), and Africa (6) to developing international sites that can perform vaccine clinical trials. In this capacity, I have taught more than 150 young investigators around the world. In 2002 and 2003, I taught the HIV-1 Vaccine development lecture for the IMM291 Comprehensive Immunology Course in the Duke Department of Immunology. Starting in 2007, I have also been awarded two R13 grants from the NIH to organize a series of International Symposia in South Africa that fosters interactions between young African scientists selected among those working in the HIV, TB, and malaria fields and senior international faculty. We have currently provided career development opportunity to more than 52 young investigators and facilitated the forum for a network of young investigators within the African continents.
  Moreover, I was one of the Co-Investigators for the MEPI project directed by Dr. J. Bartlett that collaborates with the Faculty at the Kilimanjaro Christian Medical College to develop a new curriculum of study for the students and to improve the teaching curriculum for the faculty members within the Basic Science fields. I consider this teaching as an integral part of my mandate as a scientist interested in Global Health to promote the education and interaction of the generation of young investigators, with particular focus on the African community.Mentoring has also been an important aspect of my career. Since joining the faculty in 2001, I have mentored 6 undergraduate students during their junior and senior year to perform independent research projects in my laboratory. Of them, 2 have already achieved their medical degree (Dr. Kolappa from John Hopkins University in 2009, Dr. Chaudhry from Brown University in 2009). Ms Hofmair is completing her medical degree at Duke University while achieving a MBA in medical science and a MPH in women health. Mr. Laithi graduated in 2010 and applying to Medical School for 2012. Ms. DiMarco who has recently graduated in May 2012 and has been accepted in Medical School at he University of Virginia. Mr. Hickey has completed his junior year project and we rejoin the lab after a summer internship at the University of KwaZulu-Natal (Durban, South Africa).
  
  In 2006, Marc Frahm joined my laboratory as graduate students for the Molecular Genetics and Microbiology Department. He has currently achieved the necessary requirements to defend his thesis and will graduate in August 2012.
  
  I have been a faculty mentor for the AIDS Training Grant starting in 2005 (Department of Medicine, T32). I have directly mentored two post-doctoral fellows Dr. Jie Yu (2007-2010) and Dr, Justin Pollara (2010-currently). Dr Yu is currently a Research Associate at Duke University with Dr. Chen after completing 3 years of training in my laboratory. Dr. Pollara is still in my laboratory and has already published 19 manuscripts, of which four as first author, and has five more manuscripts in preparation, two of those as first author. Dr. Pollara has been awarded a CHAVI Young Investigator for his work on fundamental insights into the HIV-1 ADCC antibody response. My career goals since joining the Duke faculty in September 2001 have been to make an impact on young investigators through basic research and teaching and mentoring undergraduate, graduate and medical students, and postdoctoral fellows at Duke University.
Available to mentor:
- PhD
- Post-Doc
- Undergraduate
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Advising & Mentoring

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