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Margaret Gradison

Professor Emeritus in Family Medicine and Community Health
Family Medicine and Community Health, Family Medicine
Duke Box 3148, Durham, NC 27710
Duke Employee Health; DUMC Box 3148, 40 Duke Medicine Circle Rm 00350, Durham, NC 27710

Selected Publications


Association between PEG3 DNA methylation and high-grade cervical intraepithelial neoplasia.

Journal Article Infect Agent Cancer · June 13, 2021 BACKGROUND: Epigenetic mechanisms are hypothesized to contribute substantially to the progression of cervical intraepithelial neoplasia (CIN) to cervical cancer, although empirical data are limited. METHODS: Women (nā€‰=ā€‰419) were enrolled at colposcopic eva ... Full text Open Access Link to item Cite

Patient preference in primary care provider type.

Journal Article Healthc (Amst) · March 2018 BACKGROUND: Given the growing roles of nurse practitioners (NPs) and physician assistants (PAs), patients are increasingly able to choose their primary care provider type. Studies examining patient preferences among provider types are limited and ours is t ... Full text Link to item Cite

Dr Carek's Commentary on Training PAs and NPs.

Journal Article Fam Med · October 2016 Link to item Cite

Dr. Carek's Commentary on Training PAs and NPs

Journal Article Family medicine · October 1, 2016 Link to item Cite

HPV genotypes and cervical intraepithelial neoplasia in a multiethnic cohort in the southeastern USA.

Journal Article Cancer Causes Control · August 2014 PURPOSE: For poorly understood reasons, invasive cervical cancer (ICC) incidence and mortality rates are higher in women of African descent. Oncogenic human papillomavirus (HPV) genotypes distribution may vary between European American (EA) and African-Ame ... Full text Open Access Link to item Cite

Quality measures for palliative care in patients with cancer: a systematic review.

Journal Article J Oncol Pract · July 2014 PURPOSE: Quality assessment is a critical component of determining the value of medical services, including palliative care. Characterization of the current portfolio of measures that assess the quality of palliative care delivered in oncology is necessary ... Full text Link to item Cite

HPV genotypes and cervical intraepithelial Neoplasiain a multiethnic cohort in the southeastern United States

Journal Article Journal of Vaccines and Vaccination · January 1, 2014 Background: For poorly understood reasons, invasive cervical cancer (ICC) incidence and mortality rates are higher in women of African descent. Oncogenic human papillomavirus (HPV) genotypes distribution may vary between European American (EA) and African ... Full text Cite

It's all about the students.

Journal Article J Physician Assist Educ · 2014 Full text Link to item Cite

HPV genotypes and cervical intraepithelial neoplasia in a multiethnic cohort in the southeastern USA

Journal Article Cancer Causes and Control · January 1, 2014 Purpose: For poorly understood reasons, invasive cervical cancer (ICC) incidence and mortality rates are higher in women of African descent. Oncogenic human papillomavirus (HPV) genotypes distribution may vary between European American (EA) and African-Ame ... Full text Cite

Advocacy: how we can support physician assistants.

Journal Article J Physician Assist Educ · 2014 Full text Link to item Cite

Prognostic significance of functional capacity and exercise behavior in patients with metastatic non-small cell lung cancer.

Journal Article Lung Cancer · May 2012 BACKGROUND: To investigate the prognostic importance of functional capacity and exercise behavior in patients with metastatic non-small cell lung cancer (NSCLC). PATIENTS AND METHODS: Using a prospective design, 118 consecutive participants with histologic ... Full text Link to item Cite

Pelvic inflammatory disease.

Journal Article Am Fam Physician · April 15, 2012 Pelvic inflammatory disease is a polymicrobial infection of the upper genital tract. It primarily affects young, sexually active women. The diagnosis is made clinically; no single test or study is sensitive or specific enough for a definitive diagnosis. Pe ... Link to item Cite

A prospective study of weight gain after premenopausal hysterectomy.

Journal Article J Womens Health (Larchmt) · May 2009 PURPOSE: Many women who have had hysterectomies have the perception that they gained weight after surgery that cannot be attributed to changes in diet or physical activity. The purpose of this analysis was to assess weight gain in premenopausal women in th ... Full text Link to item Cite

Family physicians as team leaders: "time" to share the care.

Journal Article Prev Chronic Dis · April 2009 A major contributor to shortfalls in delivery of recommended health care services is lack of physician time. On the basis of recommendations from national clinical care guidelines for preventive services and chronic disease management, and including the ti ... Link to item Cite

Menstrual, urogynecological and vasomotor changes in perimenopause and menopause

Chapter · January 1, 2009 This practical handbook provides a clear and comprehensive evidence-based guide to the care of women in primary care, intended for general and family practitioners, nurses, physician assistants, and all those who practise primary care of women. It emphasiz ... Full text Cite

Estimated time spent on preventive services by primary care physicians.

Journal Article BMC Health Serv Res · December 1, 2008 BACKGROUND: Delivery of preventive health services in primary care is lacking. One of the main barriers is lack of time. We estimated the amount of time primary care physicians spend on important preventive health services. METHODS: We analyzed a large dat ... Full text Link to item Cite

Empathy goes a long way in weight loss discussions.

Journal Article J Fam Pract · December 2007 PURPOSE: This study explores how weight-related topics are discussed between physicians and their overweight and obese female patients. METHODS: We surveyed and audio-recorded preventive health and chronic care visits with 25 overweight and obese female pa ... Link to item Cite

Physicians' beliefs about discussing obesity: results from focus groups.

Journal Article Am J Health Promot · 2007 PURPOSE: Physicians are expected to discuss weight loss with overweight and obese patients. Physicians' beliefs, outcome expectancies, and strategies for addressing weight with patients have not been examined. DESIGN: Two focus groups of family physicians ... Full text Link to item Cite

Use of email in a family practice setting: opportunities and challenges in patient- and physician-initiated communication.

Journal Article BMC Med · August 15, 2006 BACKGROUND: Electronic mail (email) has the potential to improve communication between physicians and patients. METHODS: We conducted two research studies in a family practice setting: 1) a brief, anonymous patient survey of a convenience sample to determi ... Full text Link to item Cite

Alternative models for academic family practices.

Journal Article BMC Health Serv Res · March 20, 2006 BACKGROUND: The Future of Family Medicine Report calls for a fundamental redesign of the American family physician workplace. At the same time, academic family practices are under economic pressure. Most family medicine departments do not have self-support ... Full text Link to item Cite

Problem-based learning of research skills.

Journal Article J Electrocardiol · January 2006 PURPOSE: To determine whether a short-term, problem-based educational intervention leads to increased research activity among health care practitioners. SUBJECTS AND METHODS: Participant's success was evaluated as a composite of 2 outcomes. These were (1) ... Full text Link to item Cite

Is there time for management of patients with chronic diseases in primary care?

Journal Article Ann Fam Med · 2005 PURPOSE: Despite the availability of national practice guidelines, many patients fail to receive recommended chronic disease care. Physician time constraints in primary care are likely one cause. METHODS: We applied guideline recommendations for 10 common ... Full text Link to item Cite

A problem-based approach to teaching outcomes research in family medicine residency.

Journal Article Fam Med · 2004 OBJECTIVE: This study's objective was to introduce research concepts and skills in family medicine residency through a problem-based course. METHODS: Eight third-year residents per year in 3 academic years participated. Groups of two-three were presented w ... Link to item Cite

Stroke-related knowledge among patients with access to medical care in the stroke belt.

Journal Article J Stroke Cerebrovasc Dis · 1999 North Carolina lies in the country's Stroke Belt, which is a region where cerebrovascular disease is a major public health problem. We performed an open survey of patients residing in a Stroke Belt community who had access to medical care to determine thei ... Full text Link to item Cite

Effective use of feedback.

Journal Article Fam Med · June 1998 Link to item Cite