Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.D., Hunan Medical University (China) 1994
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Neurology, Neurology, Neurocritical Care, Neurology 2013 - 2020
  • Assistant Professor of Medicine, Neurology, Clinical Science Departments 2012 - 2013
• Research
• 

  Selected Grants

  • Duke Testing Site for Stroke Preclinical Assessment Network awarded by National Institutes of Health 2023 - 2025
  • Prevention of Pain Chronification and Neuroinflammation After Traumatic Brain Injury by Neuroprotectin D1 and GPR37 Signaling awarded by Department of Defense 2021 - 2025
  • Novel anti-neuroinflammatory drug for aneurysmal subarachnoid hemorrhage (aSAH) awarded by ImmunoChem Therapeutics, LLC 2022 - 2023
  • Effects of rGDF11 on Functional Recovery Following Traumatic Brain Injury (TBI) in Mice awarded by Elevian, Inc 2021 - 2022
  • Detection and Elimination of Oncogenic Signaling Networks in Pre-malignant and Malignant Cells with Magnetic Resonance Imaging awarded by Department of Defense 2012 - 2022
  • Pharmacologic Suppression of Reperfusion Injury Following Endovascular Thrombectomy In Stroke awarded by BioMimetix JV LLC 2019 - 2021
  • rGDF11 improves outcomes after closed head injury and intracranial hemorrhage awarded by Elevian, Inc 2019 - 2020
  • CN105 to improve long-term recovery in models of intracerebral hemorrhage awarded by AegisCN LLC 2018 - 2020
  • Proteo improves outcomes after closed head injury and subarachnoid hemorrhage awarded by Prostasis, LLC 2019 - 2020
  • Extract of Erigeron breviscapus protects against brain injury in stroke awarded by Yunnan Biovalley Pharmaceutical Co., Ltd 2017 - 2020
  • Prophylactic administration of CN-105 confers neuroprotection against acute brain injury awarded by Department of Defense 2016 - 2018
  • Direct MRI of Neuroelectric Activity for Animal Neuroimaging awarded by National Institutes of Health 2011 - 2016
  • Karyopharm Theapeutics Clinipace Project awarded by Karyopharm Therapeutics 2014 - 2015
  • Eythropotien Peptides & Traumatic Brain Injury awarded by University of North Carolina - Chapel Hill 2013 - 2015
  • pH dependent neuroprotective agents improve outcome in murine SAH awarded by NeurOp Inc 2013 - 2014
  • ApoE-mimetic peptides protect against brain injury awarded by National Institutes of Health 2003 - 2005
  • Apolipoprotein E effecton the CNS immune response. awarded by National Institutes of Health 1998 - 2003
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Lewis, Nicholle E., Troy Q. Tabarestani, Brianna R. Cellini, Nina Zhang, Eric J. Marrotte, Haichen Wang, Daniel T. Laskowitz, Muhammad M. Abd-El-Barr, and Timothy D. Faw. “Effect of Acute Physical Interventions on Pathophysiology and Recovery After Spinal Cord Injury: A Comprehensive Review of the Literature.” Neurospine 19, no. 3 (September 2022): 671–86. https://doi.org/10.14245/ns.2244476.238.
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    • Tabarestani, Troy Q., Nicholle E. Lewis, Margot Kelly-Hedrick, Nina Zhang, Brianna R. Cellini, Eric J. Marrotte, Theresa Williamson, et al. “Surgical Considerations to Improve Recovery in Acute Spinal Cord Injury.” Neurospine 19, no. 3 (September 2022): 689–702. https://doi.org/10.14245/ns.2244616.308.
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    • Van Wyck, David, Bradley J. Kolls, Haichen Wang, Viviana Cantillana, Maureen Maughan, and Daniel T. Laskowitz. “Prophylactic treatment with CN-105 improves functional outcomes in a murine model of closed head injury.” Exp Brain Res 240, no. 9 (September 2022): 2413–23. https://doi.org/10.1007/s00221-022-06417-4.
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    • Li, Shuya, Runqi Wangqin, Xia Meng, Hao Li, Yi Wang, Haichen Wang, Daniel Laskowitz, Xia Chen, and Yongjun Wang. “Tolerability and Pharmacokinetics of Single Escalating and Repeated Doses of CN-105 in Healthy Participants.” Clin Ther 44, no. 5 (May 2022): 744–54. https://doi.org/10.1016/j.clinthera.2022.03.006.
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    • Wang, Haichen, Timothy D. Faw, Yufeng Lin, Shan Huang, Talaignair N. Venkatraman, Viviana Cantillana, Christopher D. Lascola, Michael L. James, and Daniel T. Laskowitz. “Neuroprotective Pentapeptide, CN-105, Improves Outcomes in Translational Models of Intracerebral Hemorrhage.” Neurocrit Care 35, no. 2 (October 2021): 441–50. https://doi.org/10.1007/s12028-020-01184-y.
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    • Creed, Jennifer, Viviana Cantillana-Riquelme, Bai Hui Yan, Shuang Ma, Dongmei Chu, Haichen Wang, Dennis A. Turner, Daniel T. Laskowitz, and Ulrike Hoffmann. “Argon Inhalation for 24 h After Closed-Head Injury Does not Improve Recovery, Neuroinflammation, or Neurologic Outcome in Mice.” Neurocrit Care 34, no. 3 (June 2021): 833–43. https://doi.org/10.1007/s12028-020-01104-0.
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    • Wang, Zeyu, Haichen Wang, Ryan Becker, Joseph Rufo, Shujie Yang, Brian E. Mace, Mengxi Wu, Jun Zou, Daniel T. Laskowitz, and Tony Jun Huang. “Acoustofluidic separation enables early diagnosis of traumatic brain injury based on circulating exosomes.” Microsyst Nanoeng 7 (2021): 20. https://doi.org/10.1038/s41378-021-00244-3.
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    • Enam, Syed Faaiz, Sajidur Rahman Kader, Nicholas Bodkin, Johnathan G. Lyon, Mark Calhoun, Cesar Azrak, Pooja Munnilal Tiwari, et al. “Evaluation of M2-like macrophage enrichment after diffuse traumatic brain injury through transient interleukin-4 expression from engineered mesenchymal stromal cells.” J Neuroinflammation 17, no. 1 (June 20, 2020): 197. https://doi.org/10.1186/s12974-020-01860-y.
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    • Lei, Beilei, Michael L. James, Ji Liu, Guanen Zhou, Talaignair N. Venkatraman, Christopher D. Lascola, Shawn K. Acheson, Laura G. Dubois, Daniel T. Laskowitz, and Haichen Wang. “Author Correction: Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage.” Sci Rep 10, no. 1 (April 20, 2020): 6898. https://doi.org/10.1038/s41598-020-63178-2.
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    • Krishnamurthy, Kamesh, Viviana Cantillana, Haichen Wang, Patrick M. Sullivan, Bradley J. Kolls, Xintong Ge, Yufeng Lin, Brian Mace, and Daniel T. Laskowitz. “ApoE mimetic improves pathology and memory in a model of Alzheimer's disease.” Brain Res 1733 (April 15, 2020): 146685. https://doi.org/10.1016/j.brainres.2020.146685.
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    • James, Michael L., Jordan M. Komisarow, Haichen Wang, and Daniel T. Laskowitz. “Therapeutic Development of Apolipoprotein E Mimetics for Acute Brain Injury: Augmenting Endogenous Responses to Reduce Secondary Injury.” Neurotherapeutics 17, no. 2 (April 2020): 475–83. https://doi.org/10.1007/s13311-020-00858-x.
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    • Li, Dai, Shan Huang, Zhenyu Yin, Jialin Zhu, Xintong Ge, Zhaoli Han, Jin Tan, et al. “Increases in miR-124-3p in Microglial Exosomes Confer Neuroprotective Effects by Targeting FIP200-Mediated Neuronal Autophagy Following Traumatic Brain Injury.” Neurochem Res 44, no. 8 (August 2019): 1903–23. https://doi.org/10.1007/s11064-019-02825-1.
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    • Ge, Xintong, Wenzhu Li, Shan Huang, Zhenyu Yin, Mengchen Yang, Zhenying Han, Zhaoli Han, et al. “Increased miR-21-3p in Injured Brain Microvascular Endothelial Cells after Traumatic Brain Injury Aggravates Blood-Brain Barrier Damage by Promoting Cellular Apoptosis and Inflammation through Targeting MAT2B.” J Neurotrauma 36, no. 8 (April 15, 2019): 1291–1305. https://doi.org/10.1089/neu.2018.5728.
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    • Liu, Ji, Guanen Zhou, Bradley J. Kolls, Yanli Tan, Chuan Fang, Haichen Wang, and Daniel T. Laskowitz. “Apolipoprotein E mimetic peptide CN-105 improves outcome in a murine model of SAH.” Stroke Vasc Neurol 3, no. 4 (December 2018): 222–30. https://doi.org/10.1136/svn-2018-000152.
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    • Ge, Xintong, Wenzhu Li, Shan Huang, Zhenyu Yin, Xin Xu, Fanglian Chen, Xiaodong Kong, Haichen Wang, Jianning Zhang, and Ping Lei. “The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury.” Brain Res 1697 (October 15, 2018): 10–20. https://doi.org/10.1016/j.brainres.2018.06.008.
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    • “Erratum.” Faseb J 32, no. 4 (April 2018): 2315. https://doi.org/10.1096/fj.201700673RERR.
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    • Huang, Shan, Xintong Ge, Jinwen Yu, Zhaoli Han, Zhenyu Yin, Ying Li, Fanglian Chen, Haichen Wang, Jianning Zhang, and Ping Lei. “Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons.” Faseb J 32, no. 1 (January 2018): 512–28. https://doi.org/10.1096/fj.201700673R.
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    • Umeano, Odera, Haichen Wang, Hana Dawson, Beilei Lei, Afoma Umeano, Dawn Kernagis, and Michael L. James. “Female gonadal hormone effects on microglial activation and functional outcomes in a mouse model of moderate traumatic brain injury.” World J Crit Care Med 6, no. 2 (May 4, 2017): 107–15. https://doi.org/10.5492/wjccm.v6.i2.107.
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    • Laskowitz, Daniel T., Haichen Wang, Tony Chen, David T. Lubkin, Viviana Cantillana, Tian Ming Tu, Dawn Kernagis, et al. “Neuroprotective pentapeptide CN-105 is associated with reduced sterile inflammation and improved functional outcomes in a traumatic brain injury murine model.” Sci Rep 7 (April 21, 2017): 46461. https://doi.org/10.1038/srep46461.
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    • Tu, Tian Ming, Brad J. Kolls, Erik J. Soderblom, Viviana Cantillana, Paul Durham Ferrell, M Arthur Moseley, Haichen Wang, Hana N. Dawson, and Daniel T. Laskowitz. “Apolipoprotein E mimetic peptide, CN-105, improves outcomes in ischemic stroke.” Ann Clin Transl Neurol 4, no. 4 (April 2017): 246–65. https://doi.org/10.1002/acn3.399.
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    • Lei, Beilei, Michael L. James, Ji Liu, Guanen Zhou, Talaignair N. Venkatraman, Christopher D. Lascola, Shawn K. Acheson, Laura G. Dubois, Daniel T. Laskowitz, and Haichen Wang. “Erratum: Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage.” Sci Rep 7 (January 5, 2017): 39580. https://doi.org/10.1038/srep39580.
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    • Lei, Beilei, Michael L. James, Ji Liu, Guanen Zhou, Talaignair N. Venkatraman, Christopher D. Lascola, Shawn K. Acheson, Laura G. Dubois, Daniel T. Laskowitz, and Haichen Wang. “Neuroprotective pentapeptide CN-105 improves functional and histological outcomes in a murine model of intracerebral hemorrhage.” Sci Rep 6 (October 7, 2016): 34834. https://doi.org/10.1038/srep34834.
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    • Yang, Wei, Huaxin Sheng, and Haichen Wang. “Targeting the SUMO pathway for neuroprotection in brain ischaemia.” Stroke Vasc Neurol 1, no. 3 (September 2016): 101–7. https://doi.org/10.1136/svn-2016-000031.
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    • Zheng, Danni, Shoichiro Sato, Hisatomi Arima, Emma Heeley, Candice Delcourt, Yongjun Cao, John Chalmers, Craig S. Anderson, and Craig S. INTERACT2 Investigators. “Estimated GFR and the Effect of Intensive Blood Pressure Lowering After Acute Intracerebral Hemorrhage.” Am J Kidney Dis 68, no. 1 (July 2016): 94–102. https://doi.org/10.1053/j.ajkd.2016.01.020.
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    • Ge, Xintong, Zhaoli Han, Fanglian Chen, Haichen Wang, Baoliang Zhang, Rongcai Jiang, Ping Lei, and Jianning Zhang. “MiR-21 alleviates secondary blood-brain barrier damage after traumatic brain injury in rats.” Brain Res 1603 (April 7, 2015): 150–57. https://doi.org/10.1016/j.brainres.2015.01.009.
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    • Jeong, Seongtae, Beilei Lei, Haichen Wang, Hana N. Dawson, and Michael L. James. “Intravenous immunoglobulin G improves neurobehavioral and histological outcomes after traumatic brain injury in mice.” J Neuroimmunol 276, no. 1–2 (November 15, 2014): 112–18. https://doi.org/10.1016/j.jneuroim.2014.08.626.
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    • Ge, Xin-Tong, Ping Lei, Hai-Chen Wang, An-Ling Zhang, Zhao-Li Han, Xin Chen, Sheng-Hui Li, Rong-Cai Jiang, Chun-Sheng Kang, and Jian-Ning Zhang. “miR-21 improves the neurological outcome after traumatic brain injury in rats.” Sci Rep 4 (October 24, 2014): 6718. https://doi.org/10.1038/srep06718.
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    • Pan, Yuesong, Jing Jing, Runhua Zhang, Xingquan Zhao, Liping Liu, Haichen Wang, Gaifen Liu, Chunxue Wang, Yilong Wang, and Yongjun Wang. “Poor performance of stroke prognostication using Age and National Institutes of Health Stroke Scale-100 to predict 3- and 12-month outcomes of ischemic stroke in China National Stroke Registry.” J Stroke Cerebrovasc Dis 23, no. 9 (October 2014): 2335–40. https://doi.org/10.1016/j.jstrokecerebrovasdis.2014.04.031.
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    • Lei, Beilei, Huaxin Sheng, Haichen Wang, Christopher D. Lascola, David S. Warner, Daniel T. Laskowitz, and Michael L. James. “Intrastriatal injection of autologous blood or clostridial collagenase as murine models of intracerebral hemorrhage.” J Vis Exp, no. 89 (July 3, 2014). https://doi.org/10.3791/51439.
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    • Wang, Haichen, Michael L. James, Talaignair N. Venkatraman, Lawrence J. Wilson, Polina Lyuboslavsky, Scott J. Myers, Christopher D. Lascola, and Daniel T. Laskowitz. “pH-sensitive NMDA inhibitors improve outcome in a murine model of SAH.” Neurocrit Care 20, no. 1 (February 2014): 119–31. https://doi.org/10.1007/s12028-013-9944-9.
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    • Luo, Yang, Xianwei Wang, Yilong Wang, Chunxue Wang, Haichen Wang, David Wang, Liping Liu, et al. “Association of glomerular filtration rate with outcomes of acute stroke in type 2 diabetic patients: results from the China National Stroke Registry.” Diabetes Care 37, no. 1 (2014): 173–79. https://doi.org/10.2337/dc13-1931.
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    • Lei, Beilei, Hana N. Dawson, Briana Roulhac-Wilson, Haichen Wang, Daniel T. Laskowitz, and Michael L. James. “Tumor necrosis factor α antagonism improves neurological recovery in murine intracerebral hemorrhage.” J Neuroinflammation 10 (August 20, 2013): 103. https://doi.org/10.1186/1742-2094-10-103.
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    • Wang, Bo, Hana Dawson, Haichen Wang, Dawn Kernagis, Brad J. Kolls, Lucy Yao, and Daniel T. Laskowitz. “Lacosamide improves outcome in a murine model of traumatic brain injury.” Neurocrit Care 19, no. 1 (August 2013): 125–34. https://doi.org/10.1007/s12028-012-9808-8.
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    • Wang, Haichen, Lauren G. Anderson, Christopher D. Lascola, Michael L. James, Talaignair N. Venkatraman, Ellen R. Bennett, Shawn K. Acheson, Michael P. Vitek, and Daniel T. Laskowitz. “ApolipoproteinE mimetic peptides improve outcome after focal ischemia.” Exp Neurol 241 (March 2013): 67–74. https://doi.org/10.1016/j.expneurol.2012.11.027.
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    • Mouraviev, Vladimir, Talaignair N. Venkatraman, Artak Tovmasyan, Masaki Kimura, Matvey Tsivian, Vladimira Mouravieva, Tom J. Polascik, et al. “Mn porphyrins as novel molecular magnetic resonance imaging contrast agents.” J Endourol 26, no. 11 (November 2012): 1420–24. https://doi.org/10.1089/end.2012.0171.
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    • James, Michael L., Haichen Wang, Viviana Cantillana, Beilei Lei, Dawn N. Kernagis, Hana N. Dawson, Lori D. Klaman, and Daniel T. Laskowitz. “TT-301 inhibits microglial activation and improves outcome after central nervous system injury in adult mice.” Anesthesiology 116, no. 6 (June 2012): 1299–1311. https://doi.org/10.1097/ALN.0b013e318253a02a.
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    • Indraswari, Fransisca, Haichen Wang, Beilei Lei, Michael L. James, Dawn Kernagis, David S. Warner, Hana N. Dawson, and Daniel T. Laskowitz. “Statins improve outcome in murine models of intracranial hemorrhage and traumatic brain injury: a translational approach.” J Neurotrauma 29, no. 7 (May 1, 2012): 1388–1400. https://doi.org/10.1089/neu.2011.2117.
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    • Laskowitz, Daniel T., Beilei Lei, Hana N. Dawson, Haichen Wang, Steven T. Bellows, Dale J. Christensen, Michael P. Vitek, and Michael L. James. “The apoE-mimetic peptide, COG1410, improves functional recovery in a murine model of intracerebral hemorrhage.” Neurocrit Care 16, no. 2 (April 2012): 316–26. https://doi.org/10.1007/s12028-011-9641-5.
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    • Nimjee, Shahid M., Jens D. Lohrmann, Haichen Wang, David J. Snyder, Thomas J. Cummings, Richard C. Becker, Sabah Oney, and Bruce A. Sullenger. “Rapidly regulating platelet activity in vivo with an antidote controlled platelet inhibitor.” Mol Ther 20, no. 2 (February 2012): 391–97. https://doi.org/10.1038/mt.2011.226.
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    • Mouraviev, Vladimir, Talaignair N. Venkatraman, Artak Tovmasyan, Masaki Kimura, Matvey Tsivian, Vladimira Mouravieva, Tom J. Polascik, et al. “Mn-porphyrins as novel molecular magnetic resonance imaging contrast agents.” J Endourol, November 3, 2011, 1420–24. https://doi.org/10.1089/end.2011.0133.
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    • Blake, Charlene M., Haichen Wang, Daniel T. Laskowitz, and Bruce A. Sullenger. “A reversible aptamer improves outcome and safety in murine models of stroke and hemorrhage.” Oligonucleotides 21, no. 1 (February 2011): 11–19. https://doi.org/10.1089/oli.2010.0262.
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    • Laskowitz, Daniel T., Pingping Song, Haichen Wang, Brian Mace, Patrick M. Sullivan, Michael P. Vitek, and Hana N. Dawson. “Traumatic brain injury exacerbates neurodegenerative pathology: improvement with an apolipoprotein E-based therapeutic.” J Neurotrauma 27, no. 11 (November 2010): 1983–95. https://doi.org/10.1089/neu.2010.1396.
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    • Dawson, H. N., V. Cantillana, M. Jansen, H. Wang, M. P. Vitek, D. M. Wilcock, J. R. Lynch, and D. T. Laskowitz. “Loss of tau elicits axonal degeneration in a mouse model of Alzheimer's disease.” Neuroscience 169, no. 1 (August 11, 2010): 516–31. https://doi.org/10.1016/j.neuroscience.2010.04.037.
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    • James, Michael L., Haichen Wang, Talaignair Venkatraman, Pingping Song, Christopher D. Lascola, and Daniel T. Laskowitz. “Brain natriuretic peptide improves long-term functional recovery after acute CNS injury in mice.” J Neurotrauma 27, no. 1 (January 2010): 217–28. https://doi.org/10.1089/neu.2009.1022.
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    • Wang, H., D. J. Christensen, M. P. Vitek, P. M. Sullivan, and D. T. Laskowitz. “APOE genotype affects outcome in a murine model of sepsis: implications for a new treatment strategy.” Anaesth Intensive Care 37, no. 1 (January 2009): 38–45. https://doi.org/10.1177/0310057X0903700111.
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    • Laskowitz, Daniel T., Suzanne E. McKenna, Pingping Song, Haichen Wang, Lori Durham, Nolan Yeung, Dale Christensen, and Michael P. Vitek. “COG1410, a novel apolipoprotein E-based peptide, improves functional recovery in a murine model of traumatic brain injury.” J Neurotrauma 24, no. 7 (July 2007): 1093–1107. https://doi.org/10.1089/neu.2006.0192.
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    • Wang, Haichen, John R. Lynch, Pingping Song, Hyuk-Jun Yang, Robert B. Yates, Brian Mace, David S. Warner, John R. Guyton, and Daniel T. Laskowitz. “Simvastatin and atorvastatin improve behavioral outcome, reduce hippocampal degeneration, and improve cerebral blood flow after experimental traumatic brain injury.” Exp Neurol 206, no. 1 (July 2007): 59–69. https://doi.org/10.1016/j.expneurol.2007.03.031.
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    • Wang, H., L. Durham, H. Dawson, P. Song, D. S. Warner, P. M. Sullivan, M. P. Vitek, and D. T. Laskowitz. “Corrigendum to "an apolipoprotein e-based therapeutic improves outcome and reduces alzheimer's disease pathology following closed head injury: Evidence of pharmacogenomic interaction". [Neuroscience 144 (2007) 1324-1333]^{{star, open}} (DOI:10.1016/j.neuroscience.2006.11.017).” Neuroscience 146, no. 2 (May 11, 2007): 874. https://doi.org/10.1016/j.neuroscience.2007.01.044.
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    • Mace, Brian E., Haichen Wang, John R. Lynch, Jason Moss, Patrick Sullivan, Heidi Colton, Kevin Morgan, Jean-Christophe Renauld, and Daniel T. Laskowitz. “Apolipoprotein E modifies the CNS response to injury via a histamine-mediated pathway.” Neurol Res 29, no. 3 (April 2007): 243–50. https://doi.org/10.1179/016164107X158974.
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    • Wang, H., L. Durham, H. Dawson, P. Song, D. S. Warner, P. M. Sullivan, M. P. Vitek, and D. T. Laskowitz. “An apolipoprotein E-based therapeutic improves outcome and reduces Alzheimer's disease pathology following closed head injury: evidence of pharmacogenomic interaction.” Neuroscience 144, no. 4 (February 23, 2007): 1324–33. https://doi.org/10.1016/j.neuroscience.2006.11.017.
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    • Mesis, Rachel G., Haichen Wang, Frederick W. Lombard, Robert Yates, Michael P. Vitek, Cecil O. Borel, David S. Warner, and Daniel T. Laskowitz. “Dissociation between vasospasm and functional improvement in a murine model of subarachnoid hemorrhage.” Neurosurg Focus 21, no. 3 (September 15, 2006): E4. https://doi.org/10.3171/foc.2006.21.3.4.
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    • Leinenweber, Stephen B., Huaxin Sheng, John R. Lynch, Haichen Wang, Ines Batinić-Haberle, Daniel T. Laskowitz, James D. Crapo, Robert D. Pearlstein, and David S. Warner. “Effects of a manganese (III) porphyrin catalytic antioxidant in a mouse closed head injury model.” Eur J Pharmacol 531, no. 1–3 (February 15, 2006): 126–32. https://doi.org/10.1016/j.ejphar.2005.12.031.
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    • Gao, Junling, Haichen Wang, Huaxin Sheng, John R. Lynch, David S. Warner, Lori Durham, Michael P. Vitek, and Daniel T. Laskowitz. “A novel apoE-derived therapeutic reduces vasospasm and improves outcome in a murine model of subarachnoid hemorrhage.” Neurocrit Care 4, no. 1 (2006): 25–31. https://doi.org/10.1385/NCC:4:1:025.
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    • Wang, Haichen, Junling Gao, Timothy F. Lassiter, David L. McDonagh, Huaxin Sheng, David S. Warner, John R. Lynch, and Daniel T. Laskowitz. “Levetiracetam is neuroprotective in murine models of closed head injury and subarachnoid hemorrhage.” Neurocrit Care 5, no. 1 (2006): 71–78. https://doi.org/10.1385/NCC:5:1:71.
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    • Lynch, John R., Haichen Wang, Matthew J. McGirt, James Floyd, Allan H. Friedman, Alexander L. Coon, Robert Blessing, et al. “Simvastatin reduces vasospasm after aneurysmal subarachnoid hemorrhage: results of a pilot randomized clinical trial.” Stroke 36, no. 9 (September 2005): 2024–26. https://doi.org/10.1161/01.STR.0000177879.11607.10.
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    • Lynch, John R., Haichen Wang, Brian Mace, Stephen Leinenweber, David S. Warner, Ellen R. Bennett, Michael P. Vitek, Suzanne McKenna, and Daniel T. Laskowitz. “A novel therapeutic derived from apolipoprotein E reduces brain inflammation and improves outcome after closed head injury.” Exp Neurol 192, no. 1 (March 2005): 109–16. https://doi.org/10.1016/j.expneurol.2004.11.014.
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    • Sheng, Huaxin, Haichen Wang, Hercilia M. Homi, Ivan Spasojevic, Ines Batinic-Haberle, Robert D. Pearlstein, and David S. Warner. “A no-laminectomy spinal cord compression injury model in mice.” J Neurotrauma 21, no. 5 (May 2004): 595–603. https://doi.org/10.1089/089771504774129928.
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    • Lynch, John R., Wen Tang, Haichen Wang, Michael P. Vitek, Ellen R. Bennett, Patrick M. Sullivan, David S. Warner, and Daniel T. Laskowitz. “APOE genotype and an ApoE-mimetic peptide modify the systemic and central nervous system inflammatory response.” J Biol Chem 278, no. 49 (December 5, 2003): 48529–33. https://doi.org/10.1074/jbc.M306923200.
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  • Conference Papers

    • Drolen, Claire, Haichen Wang, Talaignair Venkatraman, Chuan Fang, Yanli Tan, Sharon Tamir, Sharon Shacham, Christopher Lascola, and Daniel Laskowitz. “Functional and Imaging Studies of the Selective Inhibitor of Nuclear Export (SINE) Compound KPT-350 in a Clinically Relevant Murine Model of Closed Head Injury (CHI).” In Neurology, Vol. 86. LIPPINCOTT WILLIAMS & WILKINS, 2016.
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    • Drolen, Claire, Haichen Wang, Talaignair Venkatraman, Chuan Fang, Yanli Tan, Sharon Tamir, Sharon Shacham, Christopher Lascola, and Daniel Laskowitz. “Functional and Imaging Studies of the Selective Inhibitor of Nuclear Export (SINE) Compound KPT-350 in a Clinically Relevant Murine Model of Closed Head Injury (CHI).” In Neurology, Vol. 86, 2016.
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    • Drolen, Claire, Haichen Wang, Talaignair Venkatraman, Chuan Fang, Yanli Tan, Sharon Tamir, Sharon Shacham, Christopher Lascola, and Daniel Laskowitz. “Functional and Imaging Studies of the Selective Inhibitor of Nuclear Export (SINE) Compound KPT-350 in a Clinically Relevant Murine Model of Closed Head Injury (CHI).” In Neurology, Vol. 86, 2016.
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    • Drolen, Claire, Haichen Wang, Talaignair Venkatraman, Chuan Fang, Yanli Tan, Sharon Tamir, Sharon Shacham, Christopher Lascola, and Daniel Laskowitz. “Functional and Imaging Studies of the Selective Inhibitor of Nuclear Export (SINE) Compound KPT-350 in a Clinically Relevant Murine Model of Closed Head Injury (CHI).” In Neurology, Vol. 86, 2016.
       Link to Item
    • Drolen, Claire, Haichen Wang, Talaignair Venkatraman, Chuan Fang, Yanli Tan, Sharon Tamir, Sharon Shacham, Christopher Lascola, and Daniel Laskowitz. “Functional and I aging Studies of the Selective Inhibitor of Nuclear Export (SINE) Compound KPT-350 in a Clinically Relevant Murine Model of Closed Head Injury (CHI).” In Neurology, Vol. 86, 2016.
       Link to Item
    • Drolen, Claire, Haichen Wang, Talaignair Venkatraman, Chuan Fang, Yanli Tan, Sharon Tamir, Sharon Shacham, Christopher Lascola, and Daniel Laskowitz. “Functional and Imaging Studies of the Selective Inhibitor of Nuclear Export (SINE) Compound KPT-350 in a Clinically Relevant Murine Model of Closed Head Injury (CHI).” In Neurology, Vol. 86, 2016.
       Link to Item
    • Lei, Beilei, Haichen Wang, Seongtae Jeong, Justin T. Hsieh, Mohammed Majeed, Hana Dawson, Huaxin Sheng, David S. Warner, and Michael L. James. “Progesterone Improves Neurobehavioral Outcome in Models of Intracerebral Hemorrhage.” In Neuroendocrinology, 103:665–77, 2016. https://doi.org/10.1159/000442204.
       Full Text  Link to Item
    • Yu, Allen W., Haichen Wang, Kyle Matthews, Daniel Laskowitz, and Cameron R. Bass. “A NOVEL MOUSE MODEL OF BLAST OF BLAST BRAIN INJURY: BLAST CONDITIONS SEEN IN THEATER.” In Journal of Neurotrauma, 30:A88–89. MARY ANN LIEBERT, INC, 2013.
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    • James, Michael, Haichen Wang, Pingping Song, and Daniel Laskowitz. “BRAIN NATRIURETIC PEPTIDE IMPROVES FUNCTIONAL OUTCOME AFTER ACUTE BRAIN INJURY IN MICE.” In Critical Care Medicine, 37:A16–A16. LIPPINCOTT WILLIAMS & WILKINS, 2009.
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