Journal ArticleJ Cardiovasc Magn Reson · July 4, 2024
BACKGROUND: Cardiovascular magnetic resonance (CMR) is increasingly utilized to evaluate expanding cardiovascular conditions. The Society for Cardiovascular Magnetic Resonance (SCMR) Registry is a central repository for real-world clinical data to support ...
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Journal ArticleEur J Heart Fail · June 2024
AIMS: The PARACOR-19 randomized controlled trial (RCT) was designed to examine the effects of sacubitril/valsartan on markers of cardiac injury, inflammation, structure, and function among patients who have recovered from acute coronavirus disease 2019 (CO ...
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Journal ArticleAm J Cardiol · October 1, 2023
Cardiac sarcoidosis (CS) is a relapsing-remitting disease, and immune suppression (IS) is the mainstay of therapy. Predictors of relapse for patients with CS in remission are not well characterized. We assessed incidence of relapse in consecutive patients ...
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Journal ArticleClin Transplant · May 2023
BACKGROUND: Heart transplantation (HT) has historically been limited by organ availability. Use of donation after circulatory death (DCD) donors addresses this limitation by utilizing previously unused hearts through use of the Organ Care System (OCS). OBJ ...
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Journal ArticleJACC Cardiovasc Imaging · December 2022
BACKGROUND: Myocardial fibrosis is a fundamental process in cardiac injury. Cardiac magnetic resonance native T1 mapping has been proposed for diagnosing myocardial fibrosis without the need for gadolinium contrast. However, recent studies suggest that T1 ...
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Journal ArticleRadiology · November 2022
Background The relationship between papillary muscle infarction (papMI) and the culprit coronary lesion has not been fully investigated. Delayed enhancement cardiac MRI may detect papMI, yet its accuracy is unknown. Flow-independent dark-blood delayed enha ...
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Journal ArticleNMR Biomed · October 2022
Myocardial lipomatous metaplasia, which can serve as substrate for ventricular arrhythmias, is usually composed of regions in which there is an admixture of fat and nonfat tissue. Although dedicated sequences for the detection of fat are available, it woul ...
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Journal ArticleJ Cardiovasc Magn Reson · July 4, 2022
The Society for Cardiovascular Magnetic Resonance (SCMR) is an international society focused on the research, education, and clinical application of cardiovascular magnetic resonance (CMR). "Cases of SCMR" is a case series hosted on the SCMR website ( http ...
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Journal ArticleJACC Cardiovasc Imaging · July 2022
BACKGROUND: Left ventricular (LV) ischemia has been variably associated with functional mitral regurgitation (FMR). Determinants of FMR in patients with ischemia are poorly understood. OBJECTIVES: This study sought to test whether contractile mechanics in ...
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Journal ArticleEuropean heart journal · December 2021
AimsCardiovascular magnetic resonance (CMR) imaging is a key diagnostic tool for the evaluation of patients with suspected cardiac tumours. Patient management is guided by the CMR diagnosis, including no further testing if a mass is excluded or if ...
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Journal ArticleJ Cardiovasc Magn Reson · October 11, 2021
The Society for Cardiovascular Magnetic Resonance (SCMR) is an international society focused on the research, education, and clinical application of cardiovascular magnetic resonance (CMR). Case of the week is a case series hosted on the SCMR website ( htt ...
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Journal ArticleJAMA Cardiol · October 1, 2021
IMPORTANCE: Vaccine-associated myocarditis is an unusual entity that has been described for the smallpox vaccine, but only anecdotal case reports have been described for other vaccines. Whether COVID-19 vaccination may be linked to the occurrence of myocar ...
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Journal ArticleNMR Biomed · October 2021
Despite clinical use of late gadolinium enhancement (LGE) for two decades, an efficient, robust fat suppression (FS) technique still does not exist for this CMR mainstay. In ischemic and non-ischemic heart disease, differentiating fibrotic tissue from infi ...
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Journal ArticleEur Radiol · July 2021
OBJECTIVE: Cardiac motion and aortic pulsatility can affect the image quality of 3D contrast-enhanced MR angiography (CE-MRA). The addition of ECG gating improves image quality; however, no studies have directly linked image quality improvements to clinica ...
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Journal ArticleJACC Cardiovasc Imaging · July 2021
OBJECTIVES: The purpose of this study was to assess whether the presence and extent of fibrosis changes over time in patients with nonischemic, dilated cardiomyopathy (DCM) receiving optimal medical therapy and the implications of any such changes on left ...
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Journal ArticleInt J Cardiol · May 1, 2021
BACKGROUND: Quantitative cardiovascular magnetic resonance T1-mapping is increasingly used for myocardial tissue characterization. However, the lack of standardization limits direct comparability between centers and wider roll-out for clinical use or trial ...
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Journal ArticleJACC Cardiovasc Imaging · April 2021
OBJECTIVES: The goal of this study was to test whether ischemia-mediated contractile dysfunction underlying the mitral valve affects functional mitral regurgitation (FMR) and the prognostic impact of FMR. BACKGROUND: FMR results from left ventricular (LV) ...
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Journal ArticleCirc Cardiovasc Imaging · February 2021
BACKGROUND: Microvascular obstruction (MO) is a pathophysiologic complication of acute myocardial infarction that portends poor prognosis; however, it is transient and disappears with infarct healing. Much remains unknown regarding its pathophysiology and ...
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Journal ArticleNMR Biomed · November 2020
Recently developed dark-blood techniques such as Flow-Independent Dark-blood DeLayed Enhancement (FIDDLE) allow simultaneous visualization of tissue contrast-enhancement and blood-pool suppression. Critical to FIDDLE is the magnetization preparation, which ...
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Journal ArticleJACC Cardiovasc Imaging · September 2019
OBJECTIVES: This study sought to evaluate the prognostic value of cardiac magnetic resonance (CMR)-derived mitral annular plane systolic excursion (MAPSE) in a large multicenter population of patients with hypertension. BACKGROUND: In patients with hyperte ...
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Journal ArticleJAMA Cardiol · March 1, 2019
IMPORTANCE: Stress cardiac magnetic resonance imaging (CMR) is not widely used in current clinical practice, and its ability to predict patient mortality is unknown. OBJECTIVE: To determine whether stress CMR is associated with patient mortality. DESIGN, S ...
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Journal ArticleJACC Cardiovasc Imaging · December 2018
OBJECTIVES: This study introduced and validated a novel flow-independent delayed enhancement technique that shows hyperenhanced myocardium while simultaneously suppressing blood-pool signal. BACKGROUND: The diagnosis and assessment of myocardial infarction ...
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Journal ArticleJACC Cardiovasc Imaging · October 2018
OBJECTIVES: The aim of this study was to evaluate the prognostic value of cardiac magnetic resonance (CMR) feature-tracking-derived global longitudinal strain (GLS) in a large multicenter population of patients with ischemic and nonischemic dilated cardiom ...
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Journal ArticleCrit Pathw Cardiol · September 2018
BACKGROUND: Stress cardiac magnetic resonance imaging (CMR) has become increasingly used in patients presenting to the emergency department (ED) with symptoms concerning for acute coronary syndrome (ACS). We hypothesized that CMR detects a number of altern ...
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Journal ArticleRadiology · February 2018
Purpose To evaluate the prognostic value of a simple index of left ventricular (LV) long-axis function-lateral mitral annular plane systolic excursion (MAPSE)-in a large multicenter population of patients with reduced ejection fraction (EF) who were underg ...
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Journal ArticleMagn Reson Med · October 2017
PURPOSE: We demonstrate an improved segmented inversion-recovery sequence that suppresses ghost artifacts arising from tissues with long T1 ( > 1.5 s). THEORY AND METHODS: Long T1 species such as pericardial fluid can create bright ghost artifacts in segme ...
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Journal ArticleJACC. Cardiovascular imaging · October 2017
ObjectivesThis study sought to determine the prevalence, correlates, and impact on cardiac mortality of right ventricular (RV) dysfunction in nonischemic cardiomyopathy.BackgroundCurrent heart failure guidelines place little emphasis on R ...
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Journal ArticleJ Cardiovasc Magn Reson · August 11, 2017
BACKGROUND: Acute myocardial infarct (AMI) size depicted by late gadolinium enhancement cardiovascular magnetic resonance (CMR) is increasingly used as an efficacy endpoint in randomized trials comparing AMI therapies. Infarct size is quantified using manu ...
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Journal ArticleAnn Thorac Surg · March 2017
BACKGROUND: Current guidelines for imaging surveillance after proximal aortic repair are not evidence based. This study sought to characterize the incidence and causes of reintervention after proximal aortic operations to provide data to guide the frequenc ...
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Journal ArticleStem Cells Transl Med · September 2015
UNLABELLED: Human pluripotent stem cells (hPSCs) are now being used for both disease modeling and cell therapy; however, efficient homologous recombination (HR) is often crucial to develop isogenic control or reporter lines. We showed that limited low-dose ...
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Journal ArticleCirc Res · July 17, 2015
RATIONALE: After acute myocardial infarction (MI), delineating the area-at-risk (AAR) is crucial for measuring how much, if any, ischemic myocardium has been salvaged. T2-weighted MRI is promoted as an excellent method to delineate the AAR. However, the ev ...
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Journal ArticleJACC Cardiovasc Imaging · June 2015
OBJECTIVES: The purpose of this study was to assess the performance of cardiac magnetic resonance (CMR) methods for discriminating acute from chronic myocardial infarction (MI). BACKGROUND: Although T2-weighted CMR is thought to be accurate in differentiat ...
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Journal ArticleUltrasound Med Biol · June 2014
The most common mechanical measure of the heart integrates ventricular strain between end-diastole and end-systole in order to provide a measure of contraction. Here an approach is described for estimating a correlate to local passive mechanical properties ...
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Journal ArticleRadiology · April 2014
PURPOSE: To compare the utility and efficacy of stress cardiac magnetic resonance (MR) imaging and stress echocardiography in an emergency setting in patients with acute chest pain (CP) and intermediate risk of coronary artery disease (CAD). MATERIALS AND ...
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Journal ArticleJACC Cardiovasc Imaging · February 2014
OBJECTIVES: This study tested the diagnostic and prognostic utility of a rapid, visual T1 assessment method for identification of cardiac amyloidosis (CA) in a "real-life" referral population undergoing cardiac magnetic resonance for suspected CA. BACKGROU ...
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Journal ArticleJ Magn Reson Imaging · December 2013
PURPOSE: To determine the accuracy and reproducibility of late gadolinium enhancement (LGE) MRI scar quantification using visual sub-segmental analysis (VSSA) versus signal threshold-based analysis in ischemic and nonischemic cardiomyopathy. MATERIALS AND ...
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Journal ArticleMagn Reson Med · November 2013
A versatile method for generating T2 -weighting is a T2 -preparation module, which has been used successfully for cardiac imaging at 1.5T. Although it has been applied at 3T, higher fields (B0 ≥ 3T) can degrade B0 and B1 homogeneity and result in nonunifor ...
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Journal ArticleJAMA · March 6, 2013
IMPORTANCE: Regional left ventricular (LV) wall thinning is believed to represent chronic transmural myocardial infarction and scar tissue. However, recent case reports using delayed-enhancement cardiovascular magnetic resonance (CMR) imaging raise the pos ...
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Journal ArticleMethodist Debakey Cardiovasc J · 2013
This article focuses on delayed contrast enhanced MRI (DE-MRI) to assess myocardial viability. We start by discussing previous literature that evaluated the potential importance of myocardial viability testing and follow up with the more recent Surgical Tr ...
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Journal ArticleRadiology · October 2012
The use of T2-weighted MR imaging to delineate the area at risk and subsequently quantify myocardial salvage is problematic on many levels. The validation studies available thus far are inadequate. Unlike the data validating DE MR imaging, in which patholo ...
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Journal ArticleEur J Radiol · August 2012
BACKGROUND: Visual determination of left ventricular ejection fraction (LVEF) by segmental scoring may be a practical alternative to volumetric analysis of cine magnetic resonance imaging (MRI). The accuracy and reproducibility of this approach for has not ...
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Journal ArticleJ Am Coll Cardiol · July 31, 2012
OBJECTIVES: We tested whether an assessment of myocardial scarring by cardiac magnetic resonance imaging (MRI) would improve risk stratification in patients evaluated for implantable cardioverter-defibrillator (ICD) implantation. BACKGROUND: Current sudden ...
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Journal ArticleJACC Cardiovasc Imaging · July 2011
OBJECTIVES: This study sought to evaluate performance characteristics of routine echo for left ventricular thrombus (LVT). BACKGROUND: Although the utility of dedicated echocardiography (echo) for LVT is established, echo is widely used as a general test f ...
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Journal ArticleJ Cardiovasc Electrophysiol · February 2011
UNLABELLED: INTRODUCTION: Cardiovascular magnetic resonance imaging (cMRI) may provide a noninvasive method to test for pulmonary vein (PV) isolation after ablation for atrial fibrillation (AF) by detecting changes in PV contraction. METHODS: PV contract ...
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Journal ArticleJ Am Coll Cardiol · December 29, 2009
In patients with known or suspected myocardial infarction (MI), cardiovascular magnetic resonance (CMR) provides a comprehensive, multifaceted view of the heart. The data, including that from a recent multicenter clinical trial, indicate that delayed-enhan ...
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Journal ArticleCirculation · November 17, 2009
BACKGROUND: In patients with sarcoidosis, sudden death is a leading cause of mortality, which may represent unrecognized cardiac involvement. Delayed-enhancement cardiovascular magnetic resonance (DE-CMR) can detect minute amounts of myocardial damage. We ...
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Journal ArticleHeart Fail Clin · July 2009
Approximately two thirds of patients with heart failure have underlying coronary artery disease. In the setting of ischemic heart disease, cardiovascular magnetic resonance has demonstrated usefulness in two ways: for the detection of coronary artery disea ...
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Journal ArticleHeart Fail Clin · July 2009
In patients who have heart failure, treatment and survival are directly related to the cause. Clinically, as a practical first step, patients are classified as having either ischemic or non-ischemic cardiomyopathy, a delineation usually based on the presen ...
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Journal ArticlePLoS Med · April 21, 2009
BACKGROUND: Unrecognized myocardial infarction (UMI) is known to constitute a substantial portion of potentially lethal coronary heart disease. However, the diagnosis of UMI is based on the appearance of incidental Q-waves on 12-lead electrocardiography. T ...
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Journal ArticleJ Am Coll Cardiol · July 8, 2008
OBJECTIVES: This study sought to assess the prevalence and markers of left ventricular (LV) thrombus among patients with systolic dysfunction. BACKGROUND: Prior studies have yielded discordant findings regarding prevalence and markers of LV thrombus. Delay ...
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Journal ArticleJACC Cardiovasc Imaging · July 2008
OBJECTIVES: We wanted to assess the value of cardiovascular magnetic resonance (CMR) stress testing for evaluation of women with suspected coronary artery disease (CAD). BACKGROUND: A combined perfusion and infarction CMR examination can accurately diagnos ...
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Journal ArticleCirc Cardiovasc Imaging · July 2008
BACKGROUND: Atrial septal defect (ASD) flow can be measured indirectly by velocity-encoded cardiovascular magnetic resonance (veCMR) of the pulmonary artery and aorta. Imaging the secundum ASD en face could potentially enable direct flow measurement and pr ...
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Journal ArticleMagn Reson Imaging Clin N Am · November 2007
Cardiovascular magnetic resonance (CMR) is now considered the "gold standard" for the assessment of regional and global systolic function, myocardial infarction and viability, and congenital heart disease. At specialized centers, CMR has become a clinical ...
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Journal ArticleMagn Reson Imaging Clin N Am · November 2007
With recent technical and clinical advances, adenosine stress perfusion MRI has evolved from a promising research tool to an everyday clinical test. This article reviews the current state of stress perfusion MRI. Specifically, it addresses the following to ...
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Journal ArticleCardiol Clin · February 2007
Cardiovascular magnetic resonance (CMR) is now considered the "gold standard" for the assessment of regional and global systolic function, myocardial infarction and viability, and congenital heart disease. At specialized centers, CMR has become a clinical ...
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Journal ArticleCardiol Clin · February 2007
With recent technical and clinical advances, adenosine stress perfusion MRI has evolved from a promising research tool to an everyday clinical test. This article reviews the current state of stress perfusion MRI. Specifically, it addresses the following to ...
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Journal ArticleJ Nucl Cardiol · 2007
BACKGROUND: Diagnostic assessment of myocardial perfusion impacts the management of patients with suspected coronary artery disease (CAD). Although various image displays are available for single photon emission computed tomography (SPECT) interpretation, ...
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