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Hashim Al-Hashimi
Adjunct Professor in the Department of Biochemistry
Biochemistry
hashim.al.hashimi@duke.edu
Research
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At a Glance
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Credentials
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Academic Experience
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Expertise
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Research
Selected Grants
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Publications
Selected Publications
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Teaching
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Advising & Mentoring
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Selected Grants
The Center for HIV RNA Studies (CRNA)
Research
Principal Investigator ·
Awarded by Regents of the University of Michigan ·
2014 - 2022
Deep Topological Sampling of Protein Structures - non-competing renewal for Year 4
Research
Significant Contributor ·
Awarded by National Institutes of Health ·
2017 - 2022
Medical Scientist Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
1997 - 2022
Structural studies of post-transcriptionally modified snRNAs and their role in congenital heart disease
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2020 - 2022
Targeting Regulatory RNA elements in the Zika Virus
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2020 - 2022
Fundamental Studies of RNA Conformational Thermodynamics
Research
Principal Investigator ·
Awarded by Stanford University ·
2019 - 2022
Role of DNA structural dynamics in mutagenesis and oncogenesis
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2010 - 2022
Targeting an inactive conformation of HIV-1 TAR
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2020 - 2022
Bioinformatics and Computational Biology Training Program
Inst. Training Prgm or CME
Mentor ·
Awarded by National Institutes of Health ·
2005 - 2021
PC150506: Small molecule targeting of RNA splice variants driving tumor aggressiveness
Research
Collaborator ·
Awarded by United States Army Medical Research Acquisition Activity ·
2016 - 2020
Development and Application of IR-based methods for visualizing Hoogsteen base pairs in the Nucleosome Particle
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2017 - 2019
Fundamental Studies of RNA Folding Project 1
Research
Principal Investigator ·
Awarded by Stanford University ·
2014 - 2019
Structure, Function and Targetability of RNA Excited States
Fellowship
Principal Investigator ·
Awarded by National Institutes of Health ·
2017 - 2018
Functions of Carbon-Oxygen Hydrogen Bonding in Biological Methyl Transfer
Research
Principal Investigator ·
Awarded by University of Michigan ·
2014 - 2018
Fundamental Studies of RNA Folding Project 2
Research
Principal Investigator ·
Awarded by Stanford University ·
2014 - 2018
Fundamental Studies of RNA Folding Project 3
Research
Principal Investigator ·
Awarded by Stanford University ·
2014 - 2018
Acquisition of a MALDI-TOF Mass Spectrometer System at Duke University
Equipment
Major User ·
Awarded by North Carolina Biotechnology Center ·
2017 - 2018
Targeting HIV-1 Regulatory RNA Elements
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2005 - 2016
Dynamics of Normal and Damaged DNA Under Relaxed and Supercoiled Conditions
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2010 - 2015
Mechanism of an Acid Activated Chaperone
Research
Principal Investigator ·
Awarded by Regents of the University of Michigan ·
2014 - 2015
Biological Activity of Lead Compounds Targeting HIV-1 TAR RNA
Research
Principal Investigator ·
Awarded by Regents of the University of Michigan ·
2014 - 2014
Mechanism of an Acid Activated Chaperone
Research
Principal Investigator ·
Awarded by Regents of the University of Michigan ·
2014 - 2014
