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Heath Gasier

Associate Professor in Anesthesiology
Anesthesiology
DUMC 3823, 40 Medicine Circle, Durham, NC 27710
Center for Hyperbaric Medicine, & Environmental Physiology, DUMC 3823 Durham, NC 27710
Office hours Monday-Friday, 8:30 am - 5:00 pm  

Research Interests


To understand how high and low oxygen levels influence mitochondrial quality control and bioenergetics. 

Selected Grants


Applied Physiology of CNS Oxygen Toxicity: Mechanisms in Humans

ResearchCo Investigator · Awarded by Office of Naval Research · 2023 - 2026

The Role of GABA in Susceptibility to Oxygen Toxicity with Repeated HBO2 Exposure

ResearchPrincipal Investigator · Awarded by Office of Naval Research · 2022 - 2025

Ketone Ester Supplement for CNSOT Mitigation

ResearchCo Investigator · Awarded by Naval Sea Systems Command · 2022 - 2025

Repair Mechanisms of Oxidative Tissue Damage

EquipmentPrincipal Investigator · Awarded by Office of Naval Research · 2024 - 2025

AQP5 as a Target for Prophylactic Countermeasures for Pulmonary Hyperbaric Oxygen Toxicity

ResearchPrincipal Investigator · Awarded by Case Western Reserve University · 2023 - 2024

Perfluoromethane to Reduce Decompression Sickness

ResearchCo Investigator · Awarded by Naval Sea Systems Command · 2021 - 2023

Enhanced Assessment of Oxidative Tissue Damage

EquipmentPrincipal Investigator · Awarded by Office of Naval Research · 2022 - 2023

METABOLIC SYSTEM FOR IN VIVO RODENT TESTING

EquipmentPrincipal Investigator · Awarded by Office of Naval Research · 2021 - 2022

Characterizing Hyperoxia-Induced Alterations in Muscular Physiology

ResearchPrincipal Investigator · Awarded by Navy Experimental Diving Unit · 2021 - 2022

Effects of HBO2 on skeletal muscle calcium regulation and mitochondrial function

ResearchPrincipal Investigator · Awarded by Office of Naval Research · 2021 - 2022

Effects of Exercise on Skeletal Health in Iron Deficient Female Rats

ResearchPrincipal Investigator · Awarded by Henry M. Jackson Foundation · 2019 - 2021

Fellowships, Gifts, and Supported Research


Ketone Ester Supplement for CNSOT Mitigation · 2022 - 2024 Co-I · Awarded by: Naval Sea Systems Command · $825,248.00
Perfluoromethane toxicity study · 2021 - 2022 Co-I · Awarded by: Naval Sea Systems Command · $71,725.00
REMM HITT-Covid19 · 2021 - 2026 Co-I · Awarded by: National Institutes of Health (NHLBI) · $4,174,449.00
Oxidative tissue damage after HBO2 exposure using selected FDA-approved anti-epileptic drugs (AEDs) · 2020 - 2022 PI · Awarded by: Office of Naval Research · $287,000.00
Heme oxygenase-1 regulation of skeletal muscle inflammation and mitochondrial fitness in sarcopenic obesity · 2020 - 2021 PI · Awarded by: Duke University · $30,000.00
Decrements in skeletal muscle performance and mitochondrial function following hypobaric exposure and enhancing oxyhemoglobin affinity to attenuate these effects in a rodent model · 2017 - 2019 Co-I · Awarded by: Office of Naval Research · $319,988.00
The Effects of Vitamin D on Upper Respiratory Tract Infections and Immune Function in Marine Corps Recruits · 2016 - 2018 PI · Awarded by: Defense Health Program · $470,000.00
Application of low dose inhaled carbon monoxide to attenuate diet induced obesity in rats · 2015 - 2018 PI · Awarded by: Uniformed Services University of the Health Sciences · $90,000.00
The importance of nitrate-nitrite-NO pathway in regulating systemic blood flow under hypobaric and the impact of nitrate supplementation on exercise performance at high altitude · 2012 - 2013 Co-I · Awarded by: Office of Naval Research · $198,179.00
Exhaled nitric oxide (NO) and carbon monoxide (CO) as noninvasive markers of hyperbaric oxidative stress in humans · 2010 - 2013 Co-I · Awarded by: Office of Naval Research · $435,000.00
The role of nitric oxide in hyperbaric hyperbaric stress · 2010 - 2011 Co-I · Awarded by: Defense Health Medical Research and Development Program · $247,000.00
Bone Health in US Submariners · 2010 - 2013 PI · Awarded by: Office of Naval Research · $828,000.00
The effects of immediate post-resistance exercise protein ingestion on protein synthesis using 2H2O · 2006 - 2007 PI · Awarded by: Gatorade Sports Science Institute · $1,500.00
The effects of a carbohydrate-protein drink on performance and mood in US pararescue trainees · 2005 - 2006 PI · Awarded by: USAF, 59th Clinical Research Squadron · $5,000.00