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Heather Alyse King

Assistant Professor in Population Health Sciences
Population Health Sciences

Selected Publications


Understanding veterans' experiences with lung cancer and psychological distress: A multimethod approach.

Journal Article Psychol Serv · November 2024 Psychological distress while coping with cancer is a highly prevalent and yet underrecognized and burdensome adverse effect of cancer diagnosis and treatment. Left unaddressed, psychological distress can further exacerbate poor mental health, negatively in ... Full text Open Access Link to item Cite

A Clinician's Guide to Understanding Bias in Critical Clinical Prediction Models.

Journal Article Crit Care Clin · October 2024 This narrative review focuses on the role of clinical prediction models in supporting informed decision-making in critical care, emphasizing their 2 forms: traditional scores and artificial intelligence (AI)-based models. Acknowledging the potential for bo ... Full text Link to item Cite

Validating a tool to measure spiritual beliefs, needs and resources in serious illness: The I-SPIRIT.

Journal Article J Am Geriatr Soc · July 2024 BACKGROUND: Seriously ill patients rely on spiritual and existential beliefs to support coping and approach crucial treatment and healthcare decisions. Yet, we lack gold standard, validated approaches to gathering information on those spiritual beliefs. Th ... Full text Link to item Cite

Understanding pathways from implementation to sustainment: a longitudinal, mixed methods analysis of promising practices implemented in the Veterans Health Administration.

Journal Article Implement Sci · May 7, 2024 BACKGROUND: The Veterans Health Administration (VHA) is the United States largest learning health system. The Diffusion of Excellence (DoE) program is a large-scale model of diffusion that identifies and diffuses evidence-informed practices across VHA. Dur ... Full text Link to item Cite

Factors influencing support for the implementation of community-based out-of-hospital cardiac arrest interventions in high- and low-performing counties.

Journal Article Resusc Plus · March 2024 AIM OF THE STUDY: Survival to hospital discharge from out-of-hospital cardiac arrest (OHCA) after receiving treatment from emergency medical services (EMS) is less than 10% in the United States. Community-focused interventions improve survival rates, but t ... Full text Open Access Link to item Cite

Moving Beyond Mortality: Development and Application of a Desirability of Outcome Ranking (DOOR) Endpoint for Hospital-Acquired Bacterial Pneumonia and Ventilator-Associated Bacterial Pneumonia.

Journal Article Clinical infectious diseases : an official publication of the Infectious Diseases Society of America · February 2024 BackgroundHospital-acquired and ventilator-associated bacterial pneumonia (HABP/VABP) are frequently caused by multidrug-resistant organisms. Patient-centered endpoints in clinical trials are needed to develop new antibiotics for HABP/VABP. Desira ... Full text Cite

Implementation of Direct-to-Patient Mobile Teledermatology in VA.

Journal Article J Gen Intern Med · February 2024 BACKGROUND: Innovative technology can enhance patient access to healthcare but must be successfully implemented to be effective. OBJECTIVE: We evaluated Department of Veterans Affairs' (VA's) implementation of My VA Images, a direct-to-patient asynchronous ... Full text Link to item Cite

Implementation evaluation of a teledermatology virtual clinic at an academic medical center.

Journal Article Implement Sci Commun · October 27, 2023 BACKGROUND: Teledermatology (TD) is an evidence-based practice that may increase access to dermatologic care. We sought to use the Exploration, Preparation, Implementation, and Sustainment (EPIS) and the Reach, Efficacy, Adoption, Implementation, and Maint ... Full text Link to item Cite

The Future Ain't What It Used to Be…Out With the Old…In With the Better: Antibacterial Resistance Leadership Group Innovations.

Journal Article Clin Infect Dis · October 16, 2023 Clinical research networks conduct important studies that would not otherwise be performed by other entities. In the case of the Antibacterial Resistance Leadership Group (ARLG), such studies include diagnostic studies using master protocols, controlled ph ... Full text Link to item Cite

Partner engagement for planning and development of non-pharmacological care pathways in the AIM-Back trial.

Journal Article Clin Trials · October 2023 BACKGROUND/AIMS: Embedded pragmatic clinical trials are increasingly recommended for non-pharmacological pain care research due to their focus on examining intervention effectiveness within real-world settings. Engagement with patients, health care provide ... Full text Open Access Link to item Cite

Feasibility of Implementation of a Mobile Digital Personal Health Record to Coordinate Care for Children and Youth With Special Health Care Needs in Primary Care: Protocol for a Mixed Methods Study.

Journal Article JMIR Res Protoc · September 20, 2023 BACKGROUND: Electronic health record (EHR)-integrated digital personal health records (PHRs) via Fast Healthcare Interoperability Resources (FHIR) are promising digital health tools to support care coordination (CC) for children and youth with special heal ... Full text Link to item Cite

Supporting Veteran's Administration Medical Center Directors' Decisions When Adopting Innovative Practices: Development and Implementation of the "QuickView" and "WishList" Tools.

Journal Article Perm J · September 15, 2023 Background Since 2015, the Veterans Health Administration (VHA) Diffusion of Excellence Program has supported spread of practices developed by frontline employees. Shark Tank-style competitions encourage "Sharks" nationwide (VHA medical center/regional dir ... Full text Link to item Cite

Impact of COVID-19 pandemic on nonpharmacological pain management trials in military and veteran healthcare settings: an evaluation informed by implementation science.

Journal Article Transl Behav Med · August 11, 2023 The coronavirus disease (COVID-19) pandemic disrupted healthcare and clinical research, including a suite of 11 pragmatic clinical trials (PCTs), across clinics within the Department of Veterans Affairs (VA) and the Department of Defense (DOD). These PCTs ... Full text Link to item Cite

Leveraging Organizational Conditions for Innovation: A Typology of Facility Engagement in the Veterans Health Administration Shark Tank-Style Competition.

Journal Article Perm J · June 15, 2023 Introduction The development and spread of innovation are known challenges in health care. The US Veterans Health Administration (VHA) created a "Shark Tank"-style competition directed at frontline employees. In this annual, systemwide competition, employe ... Full text Link to item Cite

Veterans Health Administration National TeleOncology Service.

Journal Article JCO Oncol Pract · April 2023 PURPOSE: As the largest integrated health care system in the United States, the Veterans Health Administration (VA) is a leader in telehealth-delivered care. All 10 million Veterans cared for within the VA are eligible for telehealth. The VA cares for appr ... Full text Link to item Cite

Identifying potentially morally injurious events from the Veteran perspective: A qualitative descriptive study

Journal Article Journal of Military, Veteran and Family Health · April 1, 2023 Introduction: Current conceptualizations of potentially morally injurious events (PMIEs) emphasize war atrocities. However, additional research on the breadth of PMIEs could inform provision of patient-centred care for those experiencing moral injury. This ... Full text Cite

Implementation Evaluation of a Teledermatology Virtual Clinic at an Academic Medical Center.

Journal Article Res Sq · February 28, 2023 BACKGROUND: Teledermatology (TD) is an evidence-based practice that may increase access to dermatologic care. We sought to evaluate implementation of TD at four Duke primary care practices. METHODS: We implemented a hybrid TD program where trained primary ... Full text Link to item Cite

Sustainment of diverse evidence-informed practices disseminated in the Veterans Health Administration (VHA): initial development and piloting of a pragmatic survey tool.

Journal Article Implement Sci Commun · January 16, 2023 BACKGROUND: There are challenges associated with measuring sustainment of evidence-informed practices (EIPs). First, the terms sustainability and sustainment are often falsely conflated: sustainability assesses the likelihood of an EIP being in use in the ... Full text Link to item Cite

Organizational Readiness for Patient-Facing Mobile Teledermatology to Care for Established Veteran Patients in the United States.

Journal Article Telemed J E Health · January 2023 Purpose: To improve patient access to skin care, the Department of Veterans Affairs (VA) developed a patient-facing asynchronous mobile teledermatology application (app), which allows patients to follow up remotely with dermatologists. To understand how th ... Full text Link to item Cite

Diffusion of excellence: evaluating a system to identify, replicate, and spread promising innovative practices across the Veterans health administration.

Journal Article Front Health Serv · 2023 INTRODUCTION: The Veterans Health Administration (VHA) Diffusion of Excellence (DoE) program provides a system to identify, replicate, and spread promising practices across the largest integrated healthcare system in the United States. DoE identifies innov ... Full text Open Access Link to item Cite

Health and social care of home-dwelling frail older adults in Switzerland: a mixed methods study.

Journal Article BMC Geriatr · November 15, 2022 BACKGROUND: Home-dwelling frail older adults are often faced with multimorbidity and complex care needs, requiring health and social care systems that support frail older adults to age in place. The objective of this paper was to investigate the types of f ... Full text Link to item Cite

Dalbavancin as an option for treatment of S. aureus bacteremia (DOTS): study protocol for a phase 2b, multicenter, randomized, open-label clinical trial.

Journal Article Trials · May 2022 BackgroundStaphylococcus aureus bacteremia is a life-threatening infection and leading cause of infective endocarditis, with mortality rates of 15-50%. Treatment typically requires prolonged administration of parenteral therapy, itself associated ... Full text Open Access Cite

eConsults' Impact on Care Access and Wait Times in Rheumatology.

Journal Article J Clin Rheumatol · April 1, 2022 BACKGROUND/OBJECTIVE: A growing number of health systems have implemented eConsults to improve access to specialty advice, but few studies have described their use in rheumatology or impact on visit wait times. We evaluated the uptake of an eConsult progra ... Full text Open Access Link to item Cite

Use of motivational techniques to enhance unpaid caregiver engagement in a tailored skills training intervention.

Journal Article Aging Ment Health · February 2022 OBJECTIVES: The Helping Invested Families Improve Veterans' Experiences Study (HI-FIVES) evaluated a skills training program to support family caregivers of cognitively or functionally impaired persons. HI-FIVES demonstrated sustained improvements in careg ... Full text Link to item Cite

Patients' Experiences With Staphylococcus aureus and Gram-Negative Bacterial Bloodstream Infections: Results From Cognitive Interviews to Inform Assessment of Health-Related Quality of Life.

Journal Article Open Forum Infect Dis · February 2022 BACKGROUND: We previously conducted a concept elicitation study on the impact of Staphylococcus aureus and gram-negative bacterial bloodstream infections (SAB/GNB) on health-related quality of life (HRQoL) from the patient's perspective and found significa ... Full text Open Access Link to item Cite

Coordinating assessment of spiritual needs: a cross-walk of narrative and psychometric assessment tools used in palliative care.

Journal Article J Health Care Chaplain · 2022 Addressing spiritual needs of patients in healthcare settings improves patient experiences and clinical outcomes; however, non-chaplain providers typically assess spiritual needs differently (quantitative psychometric) than healthcare chaplains (long form ... Full text Link to item Cite

Collaborative spiritual care for moral injury in the veterans Affairs Healthcare System (VA): Results from a national survey of VA chaplains.

Journal Article J Health Care Chaplain · 2022 The psychospiritual nature of moral injury invites consideration regarding how chaplains understand the construct and provide care. To identify how chaplains in the VA Healthcare System conceptualize moral injury, we conducted an anonymous online survey (N ... Full text Open Access Link to item Cite

Implementation of Mobile Teledermatology: Challenges and Opportunities.

Journal Article Telemed J E Health · December 2021 Background: While teledermatology is well-established in the Department of Veterans Affairs (VA), its implementation is far from complete. To facilitate consultative teledermatology and extend its reach, VA introduced a mobile teledermatology application ( ... Full text Link to item Cite

Veterans' Interpretation of Diabetes Distress in Diabetes Self-Management: Findings From Cognitive Interviews.

Journal Article Sci Diabetes Self Manag Care · October 2021 PURPOSE: The purpose of this project was to identify additional facets of diabetes distress (DD) in veterans that may be present due to the veteran's military-related experience. METHODS: The study team completed cognitive interviews with veterans with typ ... Full text Open Access Link to item Cite

Patients' Experiences With Staphylococcus aureus and Gram-negative Bacterial Bloodstream Infections: A Qualitative Descriptive Study and Concept Elicitation Phase To Inform Measurement of Patient-reported Quality of Life.

Journal Article Clin Infect Dis · July 15, 2021 BACKGROUND: Although Staphylococcus aureus and gram-negative bacterial bloodstream infections (SAB/GNB) cause substantial morbidity, little is known regarding patient perceptions' of their impact on quality of life (QOL). Guidance for assessing QOL and dis ... Full text Open Access Link to item Cite

Merging Implementation Practice and Science to Scale Up Promising Practices: The Veterans Health Administration (VHA) Diffusion of Excellence (DoE) Program.

Journal Article Jt Comm J Qual Patient Saf · April 2021 INTRODUCTION: The Veterans Health Administration (VHA) Diffusion of Excellence (DoE) program developed and manages a framework for identification, replication, and diffusion of promising practices throughout the nation's largest integrated health care syst ... Full text Link to item Cite

Screening for moral injury and comparatively evaluating moral injury measures in relation to mental illness symptomatology and diagnosis.

Journal Article Clin Psychol Psychother · January 2021 Moral injury merits further study to clarify its identification, prevalence, assessment and intersection with psychosocial and psychiatric problems. The present study investigated the screening potential of the Brief Moral Injury Screen (BMIS) in a sample ... Full text Link to item Cite

Improving Veteran Access to Integrated Management of Back Pain (AIM-Back): Protocol for an Embedded Pragmatic Cluster-Randomized Trial.

Journal Article Pain Med · December 12, 2020 BACKGROUND: Coordinated efforts between the National Institutes of Health, the Department of Defense, and the Department of Veterans Affairs have built the capacity for large-scale clinical research investigating the effectiveness of nonpharmacologic pain ... Full text Open Access Link to item Cite

Implementation and sustainment of diverse practices in a large integrated health system: a mixed methods study.

Journal Article Implement Sci Commun · 2020 BACKGROUND: One goal of health systems seeking to evolve into learning health systems is to accelerate the implementation and sustainment of evidence-based practices (EBPs). As part of this evolution, the Veterans Health Administration (VHA) developed the ... Full text Link to item Cite

Content Validity and Reliability of a Self-Report Measure of Medication Nonadherence in Hepatitis C Treatment.

Journal Article Dig Dis Sci · October 2019 BACKGROUND: Nonadherence to direct-acting agents (DAAs) for hepatitis C (HCV) decreases viral response. To measure nonadherence to DAAs, a reliable, valid, and easily implemented method is needed. AIMS: The goals of this study were to refine a previously v ... Full text Link to item Cite

Family Caregiver Skills Training to Improve Experiences of Care: a Randomized Clinical Trial.

Journal Article J Gen Intern Med · October 2019 OBJECTIVE: To evaluate the effectiveness of Helping Invested Families Improve Veterans' Experiences Study (HI-FIVES), a skills training program for caregivers of persons with functional or cognitive impairments. DESIGN: A two-arm RCT. SETTING: Single Veter ... Full text Link to item Cite

An Interdisciplinary Academic Detailing Approach to Decrease Inappropriate Medication Prescribing by Physician Residents for Older Veterans Treated in the Emergency Department.

Journal Article J Pharm Pract · April 2019 OBJECTIVE: To evaluate the impact of an academic detailing intervention delivered as part of a quality improvement project by a physician-pharmacist pair on (1) self-reported confidence in prescribing for older adults and (2) rates of potentially inappropr ... Full text Link to item Cite

VA Telederm study: protocol for a stepped-wedge cluster randomised trial to compare access to care for a mobile app versus a workstation-based store-and-forward teledermatology process.

Journal Article BMJ Open · December 14, 2018 INTRODUCTION: Teledermatology has emerged as an important strategy to enhance access to high-quality skin care. VA Telederm is a provider-facing, web-based mobile app designed to integrate into the existing teledermatology workflow in the US Veterans Healt ... Full text Link to item Cite

Implementing Integrated Mental Health and Chaplain Care in a National Quality Improvement Initiative.

Journal Article Psychiatr Serv · December 1, 2017 This column describes the development, implementation, and outcomes of a quality improvement learning collaborative that aimed to better integrate chaplaincy with mental health care services at 14 participating health care facilities evenly distributed acr ... Full text Link to item Cite

Implementation of Lung Cancer Screening in the Veterans Health Administration.

Journal Article JAMA Intern Med · March 1, 2017 IMPORTANCE: The US Preventive Services Task Force recommends annual lung cancer screening (LCS) with low-dose computed tomography for current and former heavy smokers aged 55 to 80 years. There is little published experience regarding implementing this rec ... Full text Link to item Cite

Baseline Antihypertensive Drug Count and Patient Response to Hypertension Medication Management.

Journal Article J Clin Hypertens (Greenwich) · April 2016 Telemedicine-based medication management improves hypertension control, but has been evaluated primarily in patients with low antihypertensive drug counts. Its impact on patients taking three or more antihypertensive agents is not well-established. To addr ... Full text Open Access Link to item Cite

The relationship between pretreatment dietary composition and weight loss during a randomised trial of different diet approaches.

Journal Article J Hum Nutr Diet · February 2015 BACKGROUND: Identifying pretreatment dietary habits that are associated with weight-loss intervention outcomes could help guide individuals' selection of weight-loss approach among competing options. A pretreatment factor that may influence weight-loss out ... Full text Link to item Cite

Mechanisms of patient health behavior change in a randomized controlled trial of a spouse-assisted intervention.

Journal Article Psychol Health Med · 2015 Spouse-assisted interventions can improve health behaviors, but mechanisms of action are unknown. This study evaluated mediators of dietary and physical activity outcomes during a spouse-assisted intervention to improve low-density lipoprotein cholesterol. ... Full text Link to item Cite

Patient beliefs and behaviors about genomic risk for type 2 diabetes: implications for prevention.

Journal Article J Health Commun · 2015 Type 2 diabetes is a major health burden in the United States, and population trends suggest this burden will increase. High interest in, and increased availability of, testing for genetic risk of type 2 diabetes presents a new opportunity for reducing typ ... Full text Open Access Link to item Cite

Spouse health behavior outcomes from a randomized controlled trial of a spouse-assisted lifestyle change intervention to improve patient low-density lipoprotein cholesterol.

Journal Article J Behav Med · December 2014 This study evaluated spouse health behavior outcomes from a randomized controlled trial of a spouse-assisted lifestyle intervention to reduce patient low-density lipoprotein cholesterol and improve patient health behaviors. Participants were 251 spouses of ... Full text Link to item Cite

Approaches for informing optimal dose of behavioral interventions.

Journal Article Ann Behav Med · December 2014 BACKGROUND: There is little guidance about to how select dose parameter values when designing behavioral interventions. PURPOSE: The purpose of this study is to present approaches to inform intervention duration, frequency, and amount when (1) the investig ... Full text Link to item Cite

Implementation of new clinical programs in the VHA healthcare system: the importance of early collaboration between clinical leadership and research.

Journal Article J Gen Intern Med · December 2014 Collaboration between policy, research, and clinical partners is crucial to achieving proven quality care. The Veterans Health Administration has expended great efforts towards fostering such collaborations. Through this, we have learned that an ideal coll ... Full text Link to item Cite

Daily well-being of cancer survivors: the role of somatic amplification.

Journal Article Psychooncology · September 2014 OBJECTIVE: The current study examined the role that somatic amplification plays in placing cancer survivors at an increased risk of impairments in daily well-being, specifically severity of physical symptoms, positive affect and negative affect. METHODS: P ... Full text Link to item Cite

Scheduled telephone visits in the veterans health administration patient-centered medical home.

Journal Article BMC Health Serv Res · April 1, 2014 BACKGROUND: The Veterans Health Administration (VHA) patient-centered medical home model, Patient Aligned Care Teams (PACT), includes telephone visits to improve care access and efficiency. Scheduled telephone visits can replace in-person care for some foc ... Full text Link to item Cite

Characterizing weekly self-reported antihypertensive medication nonadherence across repeated occasions.

Journal Article Patient Prefer Adherence · 2014 BACKGROUND: Little is known about weekly variability in medication nonadherence both between and within persons. PURPOSE: To characterize medication nonadherence across repeated, closely spaced occasions. METHODS: This prospective cohort study comprised fo ... Full text Link to item Cite

Intrusive Thoughts Mediate the Association between Neuroticism and Cognitive Function.

Journal Article Pers Individ Dif · November 1, 2013 Although research has established a negative association between trait neuroticism and cognition, little is known about the mechanisms that underlie this relationship. We examined the tendency to experience intrusive thoughts and negative affect as potenti ... Full text Link to item Cite

Assessing daily stress processes in social surveys by combining stressor exposure and salivary cortisol.

Journal Article Biodemography Soc Biol · 2009 This article presents a research method for assessing stress and mental health in ongoing population-based social surveys that combines self-reports of naturally occurring daily stressors with a primary marker of stress physiology, salivary cortisol. We fi ... Full text Link to item Cite