Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Hematology-Oncology, Medicine, Duke University 1996 - 1999
  • Medical Resident, Medicine, Duke University 1993 - 1996
  • M.D., Duke University 1993
• 

  Previous Appointments & Affiliations

  • Assistant Professor of Medicine, Medicine, General Internal Medicine, Medicine 2013 - 2020
  • Assistant Professor of Medicine, Medicine, Medical Oncology, Medicine 2005 - 2009
  • Associate in the Department of Medicine, Medicine, Medical Oncology, Medicine 1999 - 2005
  • Instructor, Temporary in the Department of Medicine, Medicine, Medical Oncology, Medicine 1999
• Research
• 

  Selected Grants

  • Interactions between SERMs, Soy and Black Cohosh awarded by National Institutes of Health 2003 - 2008
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Rumble, Meredith E., Francis J. Keefe, Jack D. Edinger, Glenn Affleck, P Kelly Marcom, and Heather S. Shaw. “Contribution of cancer symptoms, dysfunctional sleep related thoughts, and sleep inhibitory behaviors to the insomnia process in breast cancer survivors: a daily process analysis.” Sleep 33, no. 11 (November 2010): 1501–9. https://doi.org/10.1093/sleep/33.11.1501.
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    • Perez, Alejandra T., Banu Arun, Debu Tripathy, Mary A. Tagliaferri, Heather S. Shaw, Gretchen G. Kimmick, Isaac Cohen, et al. “A phase 1B dose escalation trial of Scutellaria barbata (BZL101) for patients with metastatic breast cancer.” Breast Cancer Res Treat 120, no. 1 (February 2010): 111–18. https://doi.org/10.1007/s10549-009-0678-5.
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    • Abernethy, Amy P., James E. Herndon, Jane L. Wheeler, Jeannette M. Day, Linda Hood, Meenal Patwardhan, Heather Shaw, and Herbert Kim Lyerly. “Feasibility and acceptability to patients of a longitudinal system for evaluating cancer-related symptoms and quality of life: pilot study of an e/Tablet data-collection system in academic oncology.” J Pain Symptom Manage 37, no. 6 (June 2009): 1027–38. https://doi.org/10.1016/j.jpainsymman.2008.07.011.
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    • Dupont, Alexandra, Jane Wheeler, James E. Herndon, April Coan, S Yousuf Zafar, Linda Hood, Meenal Patwardhan, Heather S. Shaw, H Kim Lyerly, and Amy P. Abernethy. “Use of tablet personal computers for sensitive patient-reported information.” J Support Oncol 7, no. 3 (May 2009): 91–97.
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    • Abernethy, Amy P., James E. Herndon, Jane L. Wheeler, Meenal Patwardhan, Heather Shaw, H Kim Lyerly, and Kevin Weinfurt. “Improving health care efficiency and quality using tablet personal computers to collect research-quality, patient-reported data.” Health Serv Res 43, no. 6 (December 2008): 1975–91. https://doi.org/10.1111/j.1475-6773.2008.00887.x.
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    • Anders, C., P. K. Marcom, B. Peterson, L. Gu, S. Unruhe, R. Welch, P. Lyons, et al. “A pilot study of predictive markers of chemotherapy-related amenorrhea among premenopausal women with early stage breast cancer (Cancer Investigation 26, 3, (286-295)).” Cancer Investigation 26, no. 10 (December 1, 2008): 1068. https://doi.org/10.1080/07357900802660220.
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    • Payne, Judith K., Joanne Held, Josh Thorpe, and Heather Shaw. “Effect of exercise on biomarkers, fatigue, sleep disturbances, and depressive symptoms in older women with breast cancer receiving hormonal therapy.” Oncol Nurs Forum 35, no. 4 (July 2008): 635–42. https://doi.org/10.1188/08.ONF.635-642.
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    • Perez, A. T., H. S. Shaw, G. F. Fleming, D. L. Hershman, S. Franco, C. L. Shapiro, K. Neal, I. Cohen, M. Tagliaferri, and D. Tripathy. “A phase I trial of scutellaria barbata (BZL101) for metastatic breast cancer.” J Clin Oncol 26, no. 15_suppl (May 20, 2008): 1099.
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    • Anders, Carey, P Kelly Marcom, Bercedis Peterson, Lin Gu, Sue Unruhe, Renee Welch, Peggy Lyons, et al. “A pilot study of predictive markers of chemotherapy-related amenorrhea among premenopausal women with early stage breast cancer.” Cancer Invest 26, no. 3 (April 2008): 286–95. https://doi.org/10.1080/07357900701829777.
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    • Shaw, H. S., and D. J. Kroll. “Actaea/Cimicifuga racemosa (black cohosh) extract and breast cancer recurrence risk: Commentary.” Focus on Alternative and Complementary Therapies 12, no. 3 (September 1, 2007): 179–80.
    • Kroll, David J., Heather S. Shaw, and Nicholas H. Oberlies. “Milk thistle nomenclature: why it matters in cancer research and pharmacokinetic studies.” Integr Cancer Ther 6, no. 2 (June 2007): 110–19. https://doi.org/10.1177/1534735407301825.
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    • Carson, James W., Kimberly M. Carson, Laura S. Porter, Francis J. Keefe, Heather Shaw, and Julie M. Miller. “Yoga for women with metastatic breast cancer: results from a pilot study.” J Pain Symptom Manage 33, no. 3 (March 2007): 331–41. https://doi.org/10.1016/j.jpainsymman.2006.08.009.
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    • Kroll, D. J., H. S. Shaw, J. M. Mathews, and N. H. Oberlies. “Simple and inexpensive methods to prevent botanical misfortune.” Acta Horticulturae 720 (January 1, 2006): 137–47. https://doi.org/10.17660/actahortic.2006.720.13.
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    • Gradishar, William J., Sergei Tjulandin, Neville Davidson, Heather Shaw, Neil Desai, Paul Bhar, Michael Hawkins, and Joyce O’Shaughnessy. “Phase III trial of nanoparticle albumin-bound paclitaxel compared with polyethylated castor oil-based paclitaxel in women with breast cancer.” J Clin Oncol 23, no. 31 (November 1, 2005): 7794–7803. https://doi.org/10.1200/JCO.2005.04.937.
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    • Kroll, D. J., and H. S. Shaw. “A near-exemplary botanical RCT: Proprietary extract of Petasites hybridus (butterbur) exhibits impressive efficacy for migraine prophylaxis.” Focus on Alternative and Complementary Therapies 10, no. 3 (September 1, 2005): 185–87. https://doi.org/10.1211/fact.10.3.0007.
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    • “Erratum.” Journal of Clinical Oncology 23, no. 6 (February 20, 2005): 1337–1337. https://doi.org/10.1200/jco.2005.12.907.
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    • Shaw, Heather S., Katherine B. Hobbs, David J. Kroll, and Victoria L. Seewaldt. “Delayed-type hypersensitivity reaction with iscador M given in combination with cytotoxic chemotherapy.” J Clin Oncol 22, no. 21 (November 1, 2004): 4432–34. https://doi.org/10.1200/JCO.2004.04.140.
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    • Shaw, Heather S., and Matthew J. Ellis. “Letrozole in the treatment of breast cancer.” Expert Opin Pharmacother 3, no. 5 (May 2002): 607–17. https://doi.org/10.1517/14656566.3.5.607.
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    • Kroll, D. J., H. S. Shaw, M. E. Wall, and N. H. Oberlies. “Variability in St. John's wort formulations is an important consideration.” Altern Ther Health Med 7, no. 6 (November 2001): 21–22.
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    • Shaw, H. S., and D. J. Kroll. “The convergence of herb pharmacodynamics and herb-drug interactions on hemostasis.” Altern Ther Health Med 7, no. 6 (November 2001): 46–47.
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    • Liu, K., J. Marshall, H. S. Shaw, R. K. Dodge, and L. J. Layfield. “Effects of chemotherapy and tamoxifen on cervical and vaginal smears in bone marrow transplant recipients.” Acta Cytol 43, no. 6 (November 1999): 1027–33. https://doi.org/10.1159/000331349.
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    • Maxwell, G. L., J. I. Risinger, H. Shaw, A. Alvarez, J. C. Barrett, P. A. Futreal, and A. Berchuck. “Mutations in the PTEN tumor suppressor gene in cervical carcinomas.” International Journal of Gynecological Cancer 8, no. 6 (December 1, 1998): 489–93. https://doi.org/10.1046/j.1525-1438.1998.98102.x.
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    • Maxwell, G. L., J. I. Risinger, B. Tong, H. Shaw, J. C. Barrett, A. Berchuck, and P. A. Futreal. “Mutation of the PTEN tumor suppressor gene is not a feature of ovarian cancers.” Gynecol Oncol 70, no. 1 (July 1998): 13–16. https://doi.org/10.1006/gyno.1998.5039.
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    • Maxwell, G. L., J. I. Risinger, C. Gumbs, H. Shaw, R. C. Bentley, J. C. Barrett, A. Berchuck, and P. A. Futreal. “Mutation of the PTEN tumor suppressor gene in endometrial hyperplasias.” Cancer Res 58, no. 12 (June 15, 1998): 2500–2503.
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  • Other Articles

    • Abernethy, A. P., J. E. Herndon, A. Coan, T. Staley, J. L. Wheeler, K. Rowe, S. K. Smith, H. Shaw, and H. K. Lyerly. “Erratum: Phase 2 pilot study of Pathfinders: A psychosocial intervention for cancer patients (Support Care Center DOI 10.1007/s00520-010-0823-z).” Supportive Care in Cancer, March 1, 2011. https://doi.org/10.1007/s00520-010-1076-6.
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  • Conference Papers

    • Perez, A. T., H. S. Shaw, G. F. Fleming, D. L. Hershman, S. Franco, C. L. Shapiro, K. Neal, I. Cohen, M. Tagliaferri, and D. Tripathy. “A phase I trial of scutellaria barbata (BZL101) for metastatic breast cancer.” In Journal of Clinical Oncology, 26:1099–1099. American Society of Clinical Oncology (ASCO), 2008. https://doi.org/10.1200/jco.2008.26.15_suppl.1099.
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    • Anders, C. K., S. A. Snyder, L. Gu, S. P. Unruhe, R. A. Welch, P. S. Lyons, G. G. Kimmick, et al. “Serum markers predictive of chemotherapy-induced premature ovarian failure among premenopausal women with early stage breast cancer.” In Breast Cancer Research and Treatment, 106:S174–S174. SPRINGER, 2007.
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    • Abernethy, A. P., J. Herndon, J. Day, L. Hood, J. Wheeler, M. B. Patwardhan, H. S. Shaw, and H. K. Lyerly. “E-tablets to collect research-quality patient-reported data.” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.
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    • Blackwell, K. L., J. Chi, C. Sidor, P. Burke, T. LaVallee, H. S. Shaw, V. Liotcheva, et al. “The effects of paclitaxel (PTX) and 2-methoxyestradiol (2-ME2) on tumor oxygenation and HIF-1 alpha in breast cancer.” In Journal of Clinical Oncology, Vol. 25. AMER SOC CLINICAL ONCOLOGY, 2007.
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    • Anders, C. K., S. A. Snyder, R. C. Barrier, W. Demark-Wahnefried, R. A. Welch, P. K. Marcom, H. S. Shaw, S. Y. Chui, and K. L. Blackwell. “Inhibin A and B as predictive markers for chemotherapy-induced premature ovarian failure (POF) among premenopausal women with early stage breast cancer (ESBC).” In Breast Cancer Research and Treatment, 94:S47–S47. SPRINGER, 2005.
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