Heather M. Stapleton
Ronie-Richele Garcia-Johnson Distinguished Professor
Professor Heather Stapleton is an environmental chemist and exposure scientist in the Nicholas School of the Environment at Duke University. Her research interests focus on identification of halogenated and organophosphate chemicals in building materials, furnishings and consumer products, and estimation of human exposure, particularly in vulnerable populations such as pregnant women and children. Her laboratory utilizes mass spectrometry, including targeted and nontargeted approaches, to characterize chemical burdens in both environmental samples and biological tissues to support environmental health research. Currently she serves as the Director for the Duke Superfund Research Center, and Director of the Duke Environmental Analysis Laboratory, which is part of NIH’s Human Health Environmental Analysis Resource.
Current Research Interests
- Human exposure in indoor environments
- Use of silicone wristbands to measure human exposure
- Chemical exposures and cancer risk
- Targeted & Nontargeted mass spectrometry methods applied to environmental samples
- Effects of halogenated organic contaminants (e.g. BFRs, PFAS) on thyroid hormone regulation
Current Appointments & Affiliations
- Ronie-Richele Garcia-Johnson Distinguished Professor, Environmental Sciences and Policy, Nicholas School of the Environment 2020
- Professor, Environmental Sciences and Policy, Nicholas School of the Environment 2020
- Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2015
Contact Information
- 9 Circuit Drive, Box 90328, LSRC Room A207, Durham, NC 27710
- Box 90328, Durham, NC 27708-0328
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heather.stapleton@duke.edu
(919) 613-8717
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Stapleton Lab website
- Background
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Education, Training, & Certifications
- Ph.D., University of Maryland, College Park 2003
- M.S., University of Maryland, College Park 2000
- B.S., Long Island University, Southhampton College 1997
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Previous Appointments & Affiliations
- Associate Professor in the Department of Civil and Environmental Engineering, Civil and Environmental Engineering, Pratt School of Engineering 2015 - 2021
- Associate Professor of Environmental Sciences and Policy in the Nicholas School of the Environment, Environmental Sciences and Policy, Nicholas School of the Environment 2012 - 2020
- Dan and Bunny Gabel Associate Professor of Environmental Ethics and Sustainable Environmental Management, Environmental Sciences and Policy, Nicholas School of the Environment 2014 - 2020
- Associate Professor in Pediatrics, Pediatrics, Children's Health Discovery Institute, Pediatrics 2018 - 2020
- Assistant Professor of Environmental Sciences and Policy, Environmental Sciences and Policy, Nicholas School of the Environment 2005 - 2012
- Assistant Professor in the Department of Civil and Environmental Engineering, Civil and Environmental Engineering, Pratt School of Engineering 2009 - 2012
- Assistant Professor of Chemistry, Chemistry, Trinity College of Arts & Sciences 2007 - 2009
- Recognition
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In the News
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JAN 20, 2023 Pratt School of Engineering -
OCT 25, 2022 Nicholas School of the Environment -
JUL 27, 2022 -
MAY 25, 2022 Nicholas School of the Environment -
MAR 22, 2022 -
JAN 11, 2022 Nicholas School of the Environment -
NOV 19, 2021 Pratt School of Engineering -
FEB 10, 2021 -
OCT 30, 2020 North Carolina Health News -
APR 22, 2020 Nicholas School of the Environment -
APR 14, 2020 -
FEB 7, 2020 -
FEB 5, 2020 Nicholas School of the Environment -
OCT 7, 2019 Nicholas School of the Environment -
FEB 18, 2019 Nicholas School of the Environment -
NOV 3, 2017 Nicholas School of the Environment -
JUL 11, 2017 -
MAY 18, 2016 Gear Junkie -
JAN 26, 2016 -
DEC 21, 2015 “CBS This Morning” -
DEC 14, 2015 -
OCT 20, 2015 Fox News -
JUL 30, 2015 Chemical Watch -
JUL 28, 2015 -
JUN 12, 2015 National Geographic -
SEP 29, 2014 The Atlantic -
SEP 22, 2014 The News & Observer
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Awards & Honors
- Expertise
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Subject Headings
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Global Scholarship
- Research
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Selected Grants
- Duke University Superfund Research Center - Developmental Co-Exposures: Mechanisms, Outcomes, and Remediation awarded by National Institutes of Health 2000 - 2027
- Impact of Early-life Exposure to Semi-Volatile Organic Compounds (SVOCs) on Neonatal and Early Childhood Immune Function awarded by National Institutes of Health 2022 - 2027
- Multimedia Measurement of PFAS in the Residential Environment: Evaluating Human Exposure Pathways awarded by Environmental Protection Agency 2022 - 2025
- Flame retardant effects on thyroid hormone regulation at the fetal-maternal interface of the placenta awarded by National Institutes of Health 2020 - 2025
- Customized Approaches for Evaluating and Reducing Chemical Exposures from Home Building Materials awarded by Department of Housing and Urban Development 2022 - 2024
- Levasseur Robert Wood Johnson Foundation Scholar Award awarded by Robert Wood Johnson Foundation 2020 - 2024
- Characterizing PFAS Exposure in NC Communities and Improving Estimates of Exposure from Indoor Air awarded by University of North Carolina - Chapel Hill 2022 - 2024
- Duke University Program in Environmental Health awarded by National Institutes of Health 2019 - 2024
- Duke Environmental Analysis Laboratory awarded by National Institutes of Health 2019 - 2024
- PFAS UNITEDD: U.S. National Investigation of Transport & Exposure from Drinking Water & Diet awarded by North Carolina State University 2019 - 2024
- The 10,000 Families Cohort: a new study to understand the environmental causes of cancer awarded by University of Minnesota 2022 - 2023
- The placenta: a novel target of sex specific neurotoxicity by fire retardants awarded by North Carolina State University 2017 - 2023
- Feasibility Assessment for Silicone Dog Tags in the Dog Aging Project awarded by University of Washington 2023
- CFN PFAS Exposure awarded by Community Foundation for Nantucket 2022 - 2023
- Developmental Toxicity of Organophosphate-based Flame Retardants awarded by University of California - Riverside 2017 - 2023
- The Racial/Ethnic and Geographical Connection Between Cognitive Function and Environmental Chemicals in Older Adults awarded by University of Southern California 2021 - 2022
- Univ. of Washington Wristband Analyses awarded by University of Washington 2021 - 2022
- A Canine Model for Human High-Risk Non-Muscle Invasive Human Bladder Cancer-Molecular and Environmental Considerations awarded by North Carolina State University 2019 - 2021
- MRI: Acquisition of a GC Hybrid Orbitrap High Resolution Tandem Mass Spectrometer for Environmental Science awarded by National Science Foundation 2018 - 2021
- Mechanisms of Environmental-Mixture Induced Metabolic Disruption awarded by National Institutes of Health 2019 - 2020
- An Investigation of Elemental Coal Ash Contamination of Soils in Iredell County, NC awarded by University of North Carolina - Chapel Hill 2020
- Children Exposure to SVOC Mixtures Indoors and Associations with Obesity awarded by National Institutes of Health 2017 - 2020
- Exposomics Reserach Project awarded by Wallace Genetic Foundation 2017 - 2019
- Duke University Program in Environmental Health awarded by National Institute of Environmental Health Sciences 2013 - 2019
- Development of affinity-directed isolation methods to identify novel hormonally active chemicals awarded by National Institutes of Health 2017 - 2019
- Maternal and Paternal Flame Retardant Exposure, Impact on Fertility and Pregnancy awarded by Harvard University 2014 - 2019
- Residential Exposure of Young Children to SVOCs awarded by Environmental Protection Agency 2014 - 2018
- Prenatal Exposure to Organophosphates and Associations with Child Growth awarded by University of North Carolina - Chapel Hill 2014 - 2017
- Analysis of Flame Retardant Chemicals in Furniture Barriers awarded by Bureau of Electronic and Appliance Repair, Home Furnishings and Thermal Insulation 2016 - 2017
- Developmental Toxicity of Organophosphate-based Flame Retardants awarded by University of California - Riverside 2014 - 2017
- Evaluation of Changes in Flame Retardant Exposure in NYC awarded by Columbia University 2015 - 2016
- Urinary Concentrations of Flame Retardant Metabolites in Mothers and Children awarded by Environmental Working Group 2015 - 2016
- Toxicokinetics and Metabolic Disrupting Actions of the Flame Retardant Mixture Firemaster 550 awarded by North Carolina State University 2014 - 2016
- Exposure to Halogenated Aromatic Compounds and Risk of Thyroid Cancer awarded by Yale University 2016
- Evaluating Human Exposure to Triphenyl Phosphate from Nail Polish Applications awarded by Environmental Working Group 2015
- Developmental Toxicity of Organophosphate-based Flame Retardants awarded by University of South Carolina 2014 - 2015
- Deiodinase Activity as a Biomarker of Response to Brominated Flame Retardants awarded by National Institutes of Health 2011 - 2015
- Current-Use Flame Retardants: Maternal Exposure and Neurodevelopment in Children awarded by University of California - Berkeley 2013 - 2015
- Duke University Superfund Research Center (P42 ES010356) awarded by National Institute of Environmental Health Sciences 2000 - 2014
- Fate of Biosolid Derived Organic Contaminants in Soils and Effects on Soil Microbial Communities awarded by National Science Foundation 2009 - 2013
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Fellowships, Supported Research, & Other Grants
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External Relationships
- San Francisco Estuary Institute
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Carignan, Courtney C., Rachel A. Bauer, Andrew Patterson, Thep Phomsopha, Eric Redman, Heather M. Stapleton, and Christopher P. Higgins. “Self-Collection Blood Test for PFASs: Comparing Volumetric Microsamplers with a Traditional Serum Approach.” Environmental Science & Technology, May 2023. https://doi.org/10.1021/acs.est.2c09852.Full Text
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Ruis, Matthew, Kate Hoffman, and Heather M. Stapleton. “Brominated flame retardants and legacy organochlorines in archived human placenta samples: Sex differences, temporal analysis and associations with infant birth weight.” Chemosphere 322 (May 2023): 138170. https://doi.org/10.1016/j.chemosphere.2023.138170.Full Text
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Crute, Christine E., Chelsea D. Landon, Angela Garner, Samantha M. Hall, Jeffery I. Everitt, Sharon Zhang, Bevin Blake, et al. “Maternal exposure to perfluorobutane sulfonate (PFBS) during pregnancy: evidence of adverse maternal and fetoplacental effects in New Zealand White (NZW) rabbits.” Toxicol Sci 191, no. 2 (February 17, 2023): 239–52. https://doi.org/10.1093/toxsci/kfac126.Full Text Link to Item
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Wiegand, Jenna, Sarah Avila-Barnard, Charvita Nemarugommula, David Lyons, Sharon Zhang, Heather M. Stapleton, and David C. Volz. “Triphenyl phosphate-induced pericardial edema in zebrafish embryos is dependent on the ionic strength of exposure media.” Environment International 172 (February 2023): 107757. https://doi.org/10.1016/j.envint.2023.107757.Full Text
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Young, Anna S., Nicholas Herkert, Heather M. Stapleton, Brent A. Coull, Russ Hauser, Thomas Zoeller, Peter A. Behnisch, Emiel Felzel, Abraham Brouwer, and Joseph G. Allen. “Hormone receptor activities of complex mixtures of known and suspect chemicals in personal silicone wristband samplers worn in office buildings.” Chemosphere 315 (February 2023): 137705. https://doi.org/10.1016/j.chemosphere.2022.137705.Full Text
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Crute, Christine E., Samantha M. Hall, Chelsea D. Landon, Angela Garner, Jeffrey I. Everitt, Sharon Zhang, Bevin Blake, et al. “Evaluating maternal exposure to an environmental per and polyfluoroalkyl substances (PFAS) mixture during pregnancy: Adverse maternal and fetoplacental effects in a New Zealand White (NZW) rabbit model.” Sci Total Environ 838, no. Pt 4 (September 10, 2022): 156499. https://doi.org/10.1016/j.scitotenv.2022.156499.Full Text Link to Item
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Hammel, Stephanie C., Shila Nordone, Sharon Zhang, Amelia M. Lorenzo, Brian Eichner, M Anthony Moody, Lynn Harrington, et al. “Infants' diminished response to DTaP vaccine is associated with exposure to organophosphate esters.” Sci Total Environ 837 (September 1, 2022): 155782. https://doi.org/10.1016/j.scitotenv.2022.155782.Full Text Link to Item
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Habre, Rima, David C. Dorman, Jonathan Abbatt, William P. Bahnfleth, Ellison Carter, Delphine Farmer, Gillian Gawne-Mittelstaedt, et al. “Why Indoor Chemistry Matters: A National Academies Consensus Report.” Environmental Science & Technology 56, no. 15 (August 2022): 10560–63. https://doi.org/10.1021/acs.est.2c04163.Full Text
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Levasseur, Jessica L., Kate Hoffman, Nicholas J. Herkert, Ellen Cooper, Duncan Hay, and Heather M. Stapleton. “Characterizing firefighter's exposure to over 130 SVOCs using silicone wristbands: A pilot study comparing on-duty and off-duty exposures.” The Science of the Total Environment 834 (August 2022): 155237. https://doi.org/10.1016/j.scitotenv.2022.155237.Full Text
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Pétré, M. -. A., K. R. Salk, H. M. Stapleton, P. L. Ferguson, G. Tait, D. R. Obenour, D. R. U. Knappe, and D. P. Genereux. “Per- and polyfluoroalkyl substances (PFAS) in river discharge: Modeling loads upstream and downstream of a PFAS manufacturing plant in the Cape Fear watershed, North Carolina.” The Science of the Total Environment 831 (July 2022): 154763. https://doi.org/10.1016/j.scitotenv.2022.154763.Full Text
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Hall, Samantha M., Sharon Zhang, Kate Hoffman, Marie Lynn Miranda, and Heather M. Stapleton. “Concentrations of per- and polyfluoroalkyl substances (PFAS) in human placental tissues and associations with birth outcomes.” Chemosphere 295 (May 2022): 133873. https://doi.org/10.1016/j.chemosphere.2022.133873.Full Text
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Reddam, Aalekhya, Nicholas Herkert, Heather M. Stapleton, and David C. Volz. “Partial dust removal in vehicles does not mitigate human exposure to organophosphate esters.” Environmental Research 205 (April 2022): 112525. https://doi.org/10.1016/j.envres.2021.112525.Full Text
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Wang, Zhen, Anna M. Wade, Daniel D. Richter, Heather M. Stapleton, James M. Kaste, and Avner Vengosh. “Legacy of anthropogenic lead in urban soils: Co-occurrence with metal(loids) and fallout radionuclides, isotopic fingerprinting, and in vitro bioaccessibility.” The Science of the Total Environment 806, no. Pt 3 (February 2022): 151276. https://doi.org/10.1016/j.scitotenv.2021.151276.Full Text Open Access Copy
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Herkert, Nicholas J., Christopher D. Kassotis, Sharon Zhang, Yuling Han, Vivek Francis Pulikkal, Mei Sun, P Lee Ferguson, and Heather M. Stapleton. “Characterization of Per- and Polyfluorinated Alkyl Substances Present in Commercial Anti-fog Products and Their In Vitro Adipogenic Activity.” Environmental Science & Technology 56, no. 2 (January 2022): 1162–73. https://doi.org/10.1021/acs.est.1c06990.Full Text
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Kozlova, Elena V., Matthew C. Valdez, Maximillian E. Denys, Anthony E. Bishay, Julia M. Krum, Kayhon M. Rabbani, Valeria Carrillo, et al. “Persistent autism-relevant behavioral phenotype and social neuropeptide alterations in female mice offspring induced by maternal transfer of PBDE congeners in the commercial mixture DE-71.” Archives of Toxicology 96, no. 1 (January 2022): 335–65. https://doi.org/10.1007/s00204-021-03163-4.Full Text
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Wise, Catherine F., Stephanie C. Hammel, Nicholas J. Herkert, Maria Ospina, Antonia M. Calafat, Matthew Breen, and Heather M. Stapleton. “Comparative Assessment of Pesticide Exposures in Domestic Dogs and Their Owners Using Silicone Passive Samplers and Biomonitoring.” Environmental Science & Technology 56, no. 2 (January 2022): 1149–61. https://doi.org/10.1021/acs.est.1c06819.Full Text
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Jenkins, Jill A., Brooke A. Baudoin, Darren Johnson, Kim J. Fernie, Heather M. Stapleton, and Natalie K. Karouna-Renier. “Establishment of baseline cytology metrics in nestling American kestrels (Falco sparverius): Immunomodulatory effects of the flame retardant isopropylated triarylphosphate isomers.” Environment International 157 (December 2021): 106779. https://doi.org/10.1016/j.envint.2021.106779.Full Text
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Young, Anna S., Nicholas Herkert, Heather M. Stapleton, Jose Guillermo Cedeño Laurent, Emily R. Jones, Piers MacNaughton, Brent A. Coull, et al. “Chemical contaminant exposures assessed using silicone wristbands among occupants in office buildings in the USA, UK, China, and India.” Environment International 156 (November 2021): 106727. https://doi.org/10.1016/j.envint.2021.106727.Full Text
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Overdahl, Kirsten E., David Gooden, Benjamin Bobay, Gordon J. Getzinger, Heather M. Stapleton, and P Lee Ferguson. “Characterizing azobenzene disperse dyes in commercial mixtures and children's polyester clothing.” Environ Pollut 287 (October 15, 2021): 117299. https://doi.org/10.1016/j.envpol.2021.117299.Full Text Open Access Copy Link to Item
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Patisaul, Heather B., Mamta Behl, Linda S. Birnbaum, Arlene Blum, Miriam L. Diamond, Seth Rojello Fernández, Helena T. Hogberg, et al. “Beyond Cholinesterase Inhibition: Developmental Neurotoxicity of Organophosphate Ester Flame Retardants and Plasticizers.” Environmental Health Perspectives 129, no. 10 (October 2021): 105001. https://doi.org/10.1289/ehp9285.Full Text
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Hoffman, Kate, Jessica L. Levasseur, Sharon Zhang, Duncan Hay, Nicholas J. Herkert, and Heather M. Stapleton. “Monitoring Human Exposure to Organophosphate Esters: Comparing Silicone Wristbands with Spot Urine Samples as Predictors of Internal Dose.” Environmental Science & Technology Letters 8, no. 9 (September 2021): 805–10. https://doi.org/10.1021/acs.estlett.1c00629.Full Text
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Kassotis, Christopher D., Kate Hoffman, Johannes Völker, Yong Pu, Almudena Veiga-Lopez, Stephanie M. Kim, Jennifer J. Schlezinger, et al. “Reproducibility of adipogenic responses to metabolism disrupting chemicals in the 3T3-L1 pre-adipocyte model system: An interlaboratory study.” Toxicology 461 (September 2021): 152900. https://doi.org/10.1016/j.tox.2021.152900.Full Text
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Gillera, Sagi Enicole A., William P. Marinello, Kevin T. Cao, Brian M. Horman, Heather M. Stapleton, and Heather B. Patisaul. “Sex-specific Disruption of the Prairie Vole Hypothalamus by Developmental Exposure to a Flame Retardant Mixture.” Endocrinology 162, no. 8 (August 2021): bqab100. https://doi.org/10.1210/endocr/bqab100.Full Text
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Wang, Zhen, Rachel M. Coyte, Ellen A. Cowan, Heather M. Stapleton, Gary S. Dwyer, and Avner Vengosh. “Evaluation and Integration of Geochemical Indicators for Detecting Trace Levels of Coal Fly Ash in Soils.” Environmental Science & Technology 55, no. 15 (August 2021): 10387–97. https://doi.org/10.1021/acs.est.1c01215.Full Text
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Kassotis, Christopher D., Kate Hoffman, Allison L. Phillips, Sharon Zhang, Ellen M. Cooper, Thomas F. Webster, and Heather M. Stapleton. “Characterization of adipogenic, PPARγ, and TRβ activities in house dust extracts and their associations with organic contaminants.” The Science of the Total Environment 758 (March 2021): 143707. https://doi.org/10.1016/j.scitotenv.2020.143707.Full Text
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Levasseur, Jessica L., Stephanie C. Hammel, Kate Hoffman, Allison L. Phillips, Sharon Zhang, Xiaoyun Ye, Antonia M. Calafat, Thomas F. Webster, and Heather M. Stapleton. “Young children's exposure to phenols in the home: Associations between house dust, hand wipes, silicone wristbands, and urinary biomarkers.” Environment International 147 (February 2021): 106317. https://doi.org/10.1016/j.envint.2020.106317.Full Text
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Gardner, C. M., K. Hoffman, H. M. Stapleton, and C. K. Gunsch. “Exposures to Semivolatile Organic Compounds in Indoor Environments and Associations with the Gut Microbiomes of Children.” Environmental Science and Technology Letters 8, no. 1 (January 12, 2021): 73–79. https://doi.org/10.1021/acs.estlett.0c00776.Full Text
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Hammel, S. C., H. M. Stapleton, B. Eichner, and K. Hoffman. “Reconsidering an Appropriate Urinary Biomarker for Flame Retardant Tris(1-chloro-2-propyl) Phosphate (TCIPP) Exposure in Children.” Environmental Science and Technology Letters 8, no. 1 (January 12, 2021): 80–85. https://doi.org/10.1021/acs.estlett.0c00794.Full Text
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Ingle, Mary E., Lidia Mínguez-Alarcón, Courtney C. Carignan, Heather M. Stapleton, Paige L. Williams, Jennifer B. Ford, Molly B. Moravek, et al. “Reproductive outcomes associated with flame retardants among couples seeking fertility treatment: A paternal perspective.” Environmental Research 192 (January 2021): 110226. https://doi.org/10.1016/j.envres.2020.110226.Full Text
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Kassotis, Christopher D., Nicholas J. Herkert, Stephanie C. Hammel, Kate Hoffman, Qianyi Xia, Seth W. Kullman, Julie Ann Sosa, and Heather M. Stapleton. “Thyroid Receptor Antagonism of Chemicals Extracted from Personal Silicone Wristbands within a Papillary Thyroid Cancer Pilot Study.” Environmental Science & Technology 54, no. 23 (December 2020): 15296–312. https://doi.org/10.1021/acs.est.0c05972.Full Text
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Witchey, Shannah K., Loujain Al Samara, Brian M. Horman, Heather M. Stapleton, and Heather B. Patisaul. “Perinatal exposure to FireMaster® 550 (FM550), brominated or organophosphate flame retardants produces sex and compound specific effects on adult Wistar rat socioemotional behavior.” Hormones and Behavior 126 (November 2020): 104853. https://doi.org/10.1016/j.yhbeh.2020.104853.Full Text
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Hall, Samantha M., Sharyle Patton, Myrto Petreas, Sharon Zhang, Allison L. Phillips, Kate Hoffman, and Heather M. Stapleton. “Per- and Polyfluoroalkyl Substances in Dust Collected from Residential Homes and Fire Stations in North America.” Environmental Science & Technology 54, no. 22 (November 2020): 14558–67. https://doi.org/10.1021/acs.est.0c04869.Full Text
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Hammel, Stephanie C., Sharon Zhang, Amelia M. Lorenzo, Brian Eichner, Heather M. Stapleton, and Kate Hoffman. “Young infants' exposure to organophosphate esters: Breast milk as a potential source of exposure.” Environ Int 143 (October 2020): 106009. https://doi.org/10.1016/j.envint.2020.106009.Full Text Link to Item
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Kozlova, Elena V., Bhuvaneswari D. Chinthirla, Pedro A. Pérez, Nicholas V. DiPatrizio, Donovan A. Argueta, Allison L. Phillips, Heather M. Stapleton, et al. “Maternal transfer of environmentally relevant polybrominated diphenyl ethers (PBDEs) produces a diabetic phenotype and disrupts glucoregulatory hormones and hepatic endocannabinoids in adult mouse female offspring.” Scientific Reports 10, no. 1 (October 2020): 18102. https://doi.org/10.1038/s41598-020-74853-9.Full Text
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Rock, Kylie D., Genevieve St Armour, Brian Horman, Allison Phillips, Matthew Ruis, Allison K. Stewart, Dereje Jima, David C. Muddiman, Heather M. Stapleton, and Heather B. Patisaul. “Effects of Prenatal Exposure to a Mixture of Organophosphate Flame Retardants on Placental Gene Expression and Serotonergic Innervation in the Fetal Rat Brain.” Toxicological Sciences : An Official Journal of the Society of Toxicology 176, no. 1 (July 2020): 203–23. https://doi.org/10.1093/toxsci/kfaa046.Full Text
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Phillips, Allison L., Nicholas J. Herkert, Jake C. Ulrich, Jessica H. Hartman, Matthew T. Ruis, Ellen M. Cooper, P Lee Ferguson, and Heather M. Stapleton. “In Vitro Metabolism of Isopropylated and tert-Butylated Triarylphosphate Esters Using Human Liver Subcellular Fractions.” Chemical Research in Toxicology 33, no. 6 (June 2020): 1428–41. https://doi.org/10.1021/acs.chemrestox.0c00002.Full Text
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Wise, Catherine F., Stephanie C. Hammel, Nicholas Herkert, Jun Ma, Alison Motsinger-Reif, Heather M. Stapleton, and Matthew Breen. “Comparative Exposure Assessment Using Silicone Passive Samplers Indicates That Domestic Dogs Are Sentinels To Support Human Health Research.” Environmental Science & Technology 54, no. 12 (June 2020): 7409–19. https://doi.org/10.1021/acs.est.9b06605.Full Text
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Gillera, Sagi Enicole A., William P. Marinello, Brian M. Horman, Allison L. Phillips, Matthew T. Ruis, Heather M. Stapleton, David M. Reif, and Heather B. Patisaul. “Sex-specific effects of perinatal FireMaster® 550 (FM 550) exposure on socioemotional behavior in prairie voles.” Neurotoxicology and Teratology 79 (May 2020): 106840. https://doi.org/10.1016/j.ntt.2019.106840.Full Text
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Ingle, Mary E., Lidia Mínguez-Alarcón, Courtney C. Carignan, Heather M. Stapleton, Paige L. Williams, Jennifer B. Ford, Molly B. Moravek, Russ Hauser, John D. Meeker, and John D. EARTH Study Team. “Exploring reproductive associations of serum polybrominated diphenyl ether and hydroxylated brominated diphenyl ether concentrations among women undergoing in vitro fertilization.” Human Reproduction (Oxford, England) 35, no. 5 (May 2020): 1199–1210. https://doi.org/10.1093/humrep/deaa063.Full Text
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Kuiper, Jordan R., Heather M. Stapleton, Marsha Wills-Karp, Xiaobin Wang, Irina Burd, and Jessie P. Buckley. “Predictors and reproducibility of urinary organophosphate ester metabolite concentrations during pregnancy and associations with birth outcomes in an urban population.” Environmental Health : A Global Access Science Source 19, no. 1 (May 2020): 55. https://doi.org/10.1186/s12940-020-00610-0.Full Text
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Hammel, Stephanie C., Kate Hoffman, Allison L. Phillips, Jessica L. Levasseur, Amelia M. Lorenzo, Thomas F. Webster, and Heather M. Stapleton. “Comparing the Use of Silicone Wristbands, Hand Wipes, And Dust to Evaluate Children's Exposure to Flame Retardants and Plasticizers.” Environmental Science & Technology 54, no. 7 (April 2020): 4484–94. https://doi.org/10.1021/acs.est.9b07909.Full Text
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Herkert, N. J., J. Merrill, C. Peters, D. Bollinger, S. Zhang, K. Hoffman, P. L. Ferguson, D. R. U. Knappe, and H. M. Stapleton. “Assessing the effectiveness of point-of-use residential drinking water filters for perfluoroalkyl substances (pfass).” Environmental Science and Technology Letters 7, no. 3 (March 10, 2020): 178–84. https://doi.org/10.1021/acs.estlett.0c00004.Full Text
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Cooper, Ellen M., Rosie Rushing, Kate Hoffman, Allison L. Phillips, Stephanie C. Hammel, Mark J. Zylka, and Heather M. Stapleton. “Strobilurin fungicides in house dust: is wallboard a source?” Journal of Exposure Science & Environmental Epidemiology 30, no. 2 (March 2020): 247–52. https://doi.org/10.1038/s41370-019-0180-z.Full Text
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Reddam, Aalekhya, George Tait, Nicholas Herkert, Stephanie C. Hammel, Heather M. Stapleton, and David C. Volz. “Longer commutes are associated with increased human exposure to tris(1,3-dichloro-2-propyl) phosphate.” Environment International 136 (March 2020): 105499. https://doi.org/10.1016/j.envint.2020.105499.Full Text
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Blake, Bevin E., Harlie A. Cope, Samantha M. Hall, Robert D. Keys, Beth W. Mahler, James McCord, Brittany Scott, et al. “Evaluation of Maternal, Embryo, and Placental Effects in CD-1 Mice following Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Hexafluoropropylene Oxide Dimer Acid (HFPO-DA or GenX).” Environmental Health Perspectives 128, no. 2 (February 2020): 27006. https://doi.org/10.1289/ehp6233.Full Text
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Escher, Beate I., Heather M. Stapleton, and Emma L. Schymanski. “Tracking complex mixtures of chemicals in our changing environment.” Science (New York, N.Y.) 367, no. 6476 (January 2020): 388–92. https://doi.org/10.1126/science.aay6636.Full Text
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Ingle, Mary E., Lidia Mínguez-Alarcón, Courtney C. Carignan, Craig M. Butt, Heather M. Stapleton, Paige L. Williams, Jennifer B. Ford, Russ Hauser, John D. Meeker, and John D. EARTH Study Team. “The association of urinary phosphorous-containing flame retardant metabolites and self-reported personal care and household product use among couples seeking fertility treatment.” Journal of Exposure Science & Environmental Epidemiology 30, no. 1 (January 2020): 107–16. https://doi.org/10.1038/s41370-019-0122-9.Full Text
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Bastiaensen, Michiel, Nele Van den Eede, Guanyong Su, Robert J. Letcher, Heather M. Stapleton, and Adrian Covaci. “Towards establishing indicative values for metabolites of organophosphate ester contaminants in human urine.” Chemosphere 236 (December 2019): 124348. https://doi.org/10.1016/j.chemosphere.2019.124348.Full Text
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Craig, Jessica A., Diana M. Ceballos, Victoria Fruh, Zoe E. Petropoulos, Joseph G. Allen, Antonia M. Calafat, Maria Ospina, et al. “Exposure of Nail Salon Workers to Phthalates, Di(2-ethylhexyl) Terephthalate, and Organophosphate Esters: A Pilot Study.” Environmental Science & Technology 53, no. 24 (December 2019): 14630–37. https://doi.org/10.1021/acs.est.9b02474.Full Text
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Doherty, Brett T., Stephanie C. Hammel, Julie L. Daniels, Heather M. Stapleton, and Kate Hoffman. “Organophosphate Esters: Are These Flame Retardants and Plasticizers Affecting Children's Health?” Current Environmental Health Reports 6, no. 4 (December 2019): 201–13. https://doi.org/10.1007/s40572-019-00258-0.Full Text
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Blum, Arlene, Mamta Behl, Linda Birnbaum, Miriam L. Diamond, Allison Phillips, Veena Singla, Nisha S. Sipes, Heather M. Stapleton, and Marta Venier. “Organophosphate Ester Flame Retardants: Are They a Regrettable Substitution for Polybrominated Diphenyl Ethers?” Environmental Science & Technology Letters 6, no. 11 (November 2019): 638–49. https://doi.org/10.1021/acs.estlett.9b00582.Full Text
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Ruis, Matthew T., Kylie D. Rock, Samantha M. Hall, Brian Horman, Heather B. Patisaul, and Heather M. Stapleton. “PBDEs Concentrate in the Fetal Portion of the Placenta: Implications for Thyroid Hormone Dysregulation.” Endocrinology 160, no. 11 (November 2019): 2748–58. https://doi.org/10.1210/en.2019-00463.Full Text
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Hammel, Stephanie C., Jessica L. Levasseur, Kate Hoffman, Allison L. Phillips, Amelia M. Lorenzo, Antonia M. Calafat, Thomas F. Webster, and Heather M. Stapleton. “Children's exposure to phthalates and non-phthalate plasticizers in the home: The TESIE study.” Environment International 132 (November 2019): 105061. https://doi.org/10.1016/j.envint.2019.105061.Full Text
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Boer, Jacob de, and Heather M. Stapleton. “Assess flame retardants with care-Response.” Science (New York, N.Y.) 365, no. 6457 (September 2019): 993. https://doi.org/10.1126/science.aay7649.Full Text
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Doherty, Brett T., Kate Hoffman, Alexander P. Keil, Stephanie M. Engel, Heather M. Stapleton, Barbara D. Goldman, Andrew F. Olshan, and Julie L. Daniels. “Prenatal exposure to organophosphate esters and behavioral development in young children in the Pregnancy, Infection, and Nutrition Study.” Neurotoxicology 73 (July 2019): 150–60. https://doi.org/10.1016/j.neuro.2019.03.007.Full Text
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Dembsey, Nicholas A., Frederick M. Brokaw, Heather M. Stapleton, Robin E. Dodson, Joy Onasch, Elisa Jazan, and Courtney C. Carignan. “Intervention to reduce gymnast exposure to flame retardants from pit foam: A case study.” Environment International 127 (June 2019): 868–75. https://doi.org/10.1016/j.envint.2019.01.084.Full Text
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Kassotis, Christopher D., Erin M. Kollitz, Kate Hoffman, Julie Ann Sosa, and Heather M. Stapleton. “Thyroid receptor antagonism as a contributory mechanism for adipogenesis induced by environmental mixtures in 3T3-L1 cells.” The Science of the Total Environment 666 (May 2019): 431–44. https://doi.org/10.1016/j.scitotenv.2019.02.273.Full Text
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Mitchell, Constance A., Aalekhya Reddam, Subham Dasgupta, Sharon Zhang, Heather M. Stapleton, and David C. Volz. “Diphenyl Phosphate-Induced Toxicity During Embryonic Development.” Environmental Science & Technology 53, no. 7 (April 2019): 3908–16. https://doi.org/10.1021/acs.est.8b07238.Full Text
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Boer, Jacob de, and Heather M. Stapleton. “Toward fire safety without chemical risk.” Science (New York, N.Y.) 364, no. 6437 (April 2019): 231–32. https://doi.org/10.1126/science.aax2054.Full Text
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Gibson, Elizabeth A., Heather M. Stapleton, Lehyla Calero, Darrell Holmes, Kimberly Burke, Rodney Martinez, Boris Cortes, et al. “Differential exposure to organophosphate flame retardants in mother-child pairs.” Chemosphere 219 (March 2019): 567–73. https://doi.org/10.1016/j.chemosphere.2018.12.008.Full Text
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Tuttle, Alexander H., Gabriela Salazar, Ellen M. Cooper, Heather M. Stapleton, and Mark J. Zylka. “Choice of vehicle affects pyraclostrobin toxicity in mice.” Chemosphere 218 (March 2019): 501–6. https://doi.org/10.1016/j.chemosphere.2018.11.126.Full Text
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Lefevre, Emilie, Lauren Redfern, Ellen M. Cooper, Heather M. Stapleton, and Claudia K. Gunsch. “Acetate promotes microbial reductive debromination of tetrabromobisphenol A during the startup phase of anaerobic wastewater sludge bioreactors.” The Science of the Total Environment 656 (March 2019): 959–68. https://doi.org/10.1016/j.scitotenv.2018.11.403.Full Text
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Doherty, Brett T., Kate Hoffman, Alexander P. Keil, Stephanie M. Engel, Heather M. Stapleton, Barbara D. Goldman, Andrew F. Olshan, and Julie L. Daniels. “Prenatal exposure to organophosphate esters and cognitive development in young children in the Pregnancy, Infection, and Nutrition Study.” Environmental Research 169 (February 2019): 33–40. https://doi.org/10.1016/j.envres.2018.10.033.Full Text
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Gibson, Elizabeth A., Heather M. Stapleton, Lehyla Calero, Darrell Holmes, Kimberly Burke, Rodney Martinez, Boris Cortes, Amy Nematollahi, David Evans, and Julie B. Herbstman. “Flame retardant exposure assessment: findings from a behavioral intervention study.” Journal of Exposure Science & Environmental Epidemiology 29, no. 1 (January 2019): 33–48. https://doi.org/10.1038/s41370-018-0049-6.Full Text
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Kassotis, Christopher D., and Heather M. Stapleton. “Endocrine-Mediated Mechanisms of Metabolic Disruption and New Approaches to Examine the Public Health Threat.” Frontiers in Endocrinology 10 (January 2019): 39. https://doi.org/10.3389/fendo.2019.00039.Full Text
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Messerlian, Carmen, Paige L. Williams, Lidia Mínguez-Alarcón, Courtney C. Carignan, Jennifer B. Ford, Craig M. Butt, John D. Meeker, et al. “Organophosphate flame-retardant metabolite concentrations and pregnancy loss among women conceiving with assisted reproductive technology.” Fertility and Sterility 110, no. 6 (November 2018): 1137-1144.e1. https://doi.org/10.1016/j.fertnstert.2018.06.045.Full Text
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Kassotis, Christopher D., Susan C. Nagel, and Heather M. Stapleton. “Unconventional oil and gas chemicals and wastewater-impacted water samples promote adipogenesis via PPARγ-dependent and independent mechanisms in 3T3-L1 cells.” The Science of the Total Environment 640–641 (November 2018): 1601–10. https://doi.org/10.1016/j.scitotenv.2018.05.030.Full Text
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Stanifer, John W., Heather M. Stapleton, Tomokazu Souma, Ashley Wittmer, Xinlu Zhao, and L Ebony Boulware. “Perfluorinated Chemicals as Emerging Environmental Threats to Kidney Health: A Scoping Review.” Clin J Am Soc Nephrol 13, no. 10 (October 8, 2018): 1479–92. https://doi.org/10.2215/CJN.04670418.Full Text Link to Item
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Hoffman, Kate, Stephanie C. Hammel, Allison L. Phillips, Amelia M. Lorenzo, Albert Chen, Antonia M. Calafat, Xiaoyun Ye, Thomas F. Webster, and Heather M. Stapleton. “Biomarkers of exposure to SVOCs in children and their demographic associations: The TESIE Study.” Environment International 119 (October 2018): 26–36. https://doi.org/10.1016/j.envint.2018.06.007.Full Text
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Kollitz, Erin M., Christopher D. Kassotis, Kate Hoffman, P Lee Ferguson, Julie Ann Sosa, and Heather M. Stapleton. “Chemical Mixtures Isolated from House Dust Disrupt Thyroid Receptor β Signaling.” Environmental Science & Technology 52, no. 20 (October 2018): 11857–64. https://doi.org/10.1021/acs.est.8b03283.Full Text
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Hammel, Stephanie C., Allison L. Phillips, Kate Hoffman, and Heather M. Stapleton. “Evaluating the Use of Silicone Wristbands To Measure Personal Exposure to Brominated Flame Retardants.” Environmental Science & Technology 52, no. 20 (October 2018): 11875–85. https://doi.org/10.1021/acs.est.8b03755.Full Text
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Holzem, R. M., H. M. Stapleton, and C. K. Gunsch. “Impact of Biosolids on Indigenous Soil Denitrifying Bacteria.” Journal of Environmental Engineering (United States) 144, no. 9 (September 1, 2018). https://doi.org/10.1061/(ASCE)EE.1943-7870.0001442.Full Text
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Phillips, Allison L., Stephanie C. Hammel, Kate Hoffman, Amelia M. Lorenzo, Albert Chen, Thomas F. Webster, and Heather M. Stapleton. “Children's residential exposure to organophosphate ester flame retardants and plasticizers: Investigating exposure pathways in the TESIE study.” Environment International 116 (July 2018): 176–85. https://doi.org/10.1016/j.envint.2018.04.013.Full Text
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Bruinstroop, Eveline, Rinkoo Dalan, Yang Cao, Yong Mong Bee, Kurumbian Chandran, Li Wei Cho, Shui Boon Soh, et al. “Low-Dose Levothyroxine Reduces Intrahepatic Lipid Content in Patients With Type 2 Diabetes Mellitus and NAFLD.” J Clin Endocrinol Metab 103, no. 7 (July 1, 2018): 2698–2706. https://doi.org/10.1210/jc.2018-00475.Full Text Link to Item
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Hoffman, Kate, Heather M. Stapleton, Amelia Lorenzo, Craig M. Butt, Linda Adair, Amy H. Herring, and Julie L. Daniels. “Prenatal exposure to organophosphates and associations with birthweight and gestational length.” Environment International 116 (July 2018): 248–54. https://doi.org/10.1016/j.envint.2018.04.016.Full Text
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Ingle, Mary E., Lidia Mínguez-Alarcón, Courtney C. Carignan, Craig M. Butt, Heather M. Stapleton, Paige L. Williams, Jennifer B. Ford, Russ Hauser, John D. Meeker, and John D. EARTH Study Team. “The association between urinary concentrations of phosphorous-containing flame retardant metabolites and semen parameters among men from a fertility clinic.” International Journal of Hygiene and Environmental Health 221, no. 5 (June 2018): 809–15. https://doi.org/10.1016/j.ijheh.2018.05.001.Full Text
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Deziel, Nicole C., Huangdi Yi, Heather M. Stapleton, Huang Huang, Nan Zhao, and Yawei Zhang. “A case-control study of exposure to organophosphate flame retardants and risk of thyroid cancer in women.” Bmc Cancer 18, no. 1 (June 2018): 637. https://doi.org/10.1186/s12885-018-4553-9.Full Text
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Kollitz, Erin M., Lauren De Carbonnel, Heather M. Stapleton, and Patrick Lee Ferguson. “The Affinity of Brominated Phenolic Compounds for Human and Zebrafish Thyroid Receptor β: Influence of Chemical Structure.” Toxicological Sciences : An Official Journal of the Society of Toxicology 163, no. 1 (May 2018): 226–39. https://doi.org/10.1093/toxsci/kfy028.Full Text
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Mitchell, Constance A., Subham Dasgupta, Sharon Zhang, Heather M. Stapleton, and David C. Volz. “Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos.” Toxicological Sciences : An Official Journal of the Society of Toxicology 163, no. 1 (May 2018): 307–18. https://doi.org/10.1093/toxsci/kfy037.Full Text
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Bello, Anila, Courtney C. Carignan, Yalong Xue, Heather M. Stapleton, and Dhimiter Bello. “Exposure to organophosphate flame retardants in spray polyurethane foam applicators: Role of dermal exposure.” Environment International 113 (April 2018): 55–65. https://doi.org/10.1016/j.envint.2018.01.020.Full Text
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Frederiksen, Marie, Heather M. Stapleton, Katrin Vorkamp, Thomas F. Webster, Niels Martin Jensen, Jens Ahm Sørensen, Flemming Nielsen, et al. “Dermal uptake and percutaneous penetration of organophosphate esters in a human skin ex vivo model.” Chemosphere 197 (April 2018): 185–92. https://doi.org/10.1016/j.chemosphere.2018.01.032.Full Text
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Leonetti, Christopher P., Craig M. Butt, and Heather M. Stapleton. “Disruption of thyroid hormone sulfotransferase activity by brominated flame retardant chemicals in the human choriocarcinoma placenta cell line, BeWo.” Chemosphere 197 (April 2018): 81–88. https://doi.org/10.1016/j.chemosphere.2017.12.172.Full Text
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Holzem, Ryan M., Courtney M. Gardner, Heather M. Stapleton, and Claudia K. Gunsch. “Using laboratory-generated biosolids to evaluate the microbial ecotoxicity of triclosan in a simulated land application scenario.” Environmental Science and Pollution Research International 25, no. 11 (April 2018): 11084–99. https://doi.org/10.1007/s11356-017-1147-z.Full Text
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Kassotis, Christopher D., Erin M. Kollitz, Patrick Lee Ferguson, and Heather M. Stapleton. “Nonionic Ethoxylated Surfactants Induce Adipogenesis in 3T3-L1 Cells.” Toxicological Sciences : An Official Journal of the Society of Toxicology 162, no. 1 (March 2018): 124–36. https://doi.org/10.1093/toxsci/kfx234.Full Text
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Carignan, Courtney C., Lidia Mínguez-Alarcón, Paige L. Williams, John D. Meeker, Heather M. Stapleton, Craig M. Butt, Thomas L. Toth, Jennifer B. Ford, Russ Hauser, and Russ EARTH Study Team. “Paternal urinary concentrations of organophosphate flame retardant metabolites, fertility measures, and pregnancy outcomes among couples undergoing in vitro fertilization.” Environment International 111 (February 2018): 232–38. https://doi.org/10.1016/j.envint.2017.12.005.Full Text
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Rock, Kylie D., Brian Horman, Allison L. Phillips, Susan L. McRitchie, Scott Watson, Jocelin Deese-Spruill, Dereje Jima, Susan Sumner, Heather M. Stapleton, and Heather B. Patisaul. “EDC IMPACT: Molecular effects of developmental FM 550 exposure in Wistar rat placenta and fetal forebrain.” Endocrine Connections 7, no. 2 (February 2018): 305–24. https://doi.org/10.1530/ec-17-0373.Full Text
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Luz, Anthony L., Christopher D. Kassotis, Heather M. Stapleton, and Joel N. Meyer. “The high-production volume fungicide pyraclostrobin induces triglyceride accumulation associated with mitochondrial dysfunction, and promotes adipocyte differentiation independent of PPARγ activation, in 3T3-L1 cells.” Toxicology 393 (January 2018): 150–59. https://doi.org/10.1016/j.tox.2017.11.010.Full Text
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Lefèvre, Emilie, Nathan Bossa, Courtney M. Gardner, Gretchen E. Gehrke, Ellen M. Cooper, Heather M. Stapleton, Heileen Hsu-Kim, and Claudia K. Gunsch. “Biochar and activated carbon act as promising amendments for promoting the microbial debromination of tetrabromobisphenol A.” Water Research 128 (January 2018): 102–10. https://doi.org/10.1016/j.watres.2017.09.047.Full Text
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Castorina, Rosemary, Asa Bradman, Heather M. Stapleton, Craig Butt, Dylan Avery, Kim G. Harley, Robert B. Gunier, Nina Holland, and Brenda Eskenazi. “Current-use flame retardants: Maternal exposure and neurodevelopment in children of the CHAMACOS cohort.” Chemosphere 189 (December 2017): 574–80. https://doi.org/10.1016/j.chemosphere.2017.09.037.Full Text
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Carignan, Courtney C., Lidia Mínguez-Alarcón, Craig M. Butt, Paige L. Williams, John D. Meeker, Heather M. Stapleton, Thomas L. Toth, Jennifer B. Ford, Russ Hauser, and Russ EARTH Study Team. “Erratum: "Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization".” Environmental Health Perspectives 125, no. 11 (November 2017): 119001. https://doi.org/10.1289/ehp2784.Full Text
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Phillips, Allison L., Stephanie C. Hammel, Alex Konstantinov, and Heather M. Stapleton. “Characterization of Individual Isopropylated and tert-Butylated Triarylphosphate (ITP and TBPP) Isomers in Several Commercial Flame Retardant Mixtures and House Dust Standard Reference Material SRM 2585.” Environmental Science & Technology 51, no. 22 (November 2017): 13443–49. https://doi.org/10.1021/acs.est.7b04179.Full Text
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Hammel, Stephanie C., Kate Hoffman, Amelia M. Lorenzo, Albert Chen, Allison L. Phillips, Craig M. Butt, Julie Ann Sosa, Thomas F. Webster, and Heather M. Stapleton. “Associations between flame retardant applications in furniture foam, house dust levels, and residents' serum levels.” Environment International 107 (October 2017): 181–89. https://doi.org/10.1016/j.envint.2017.07.015.Full Text
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Siebenaler, Rebecca, Rochelle Cameron, Craig M. Butt, Kate Hoffman, Christopher P. Higgins, and Heather M. Stapleton. “Serum perfluoroalkyl acids (PFAAs) and associations with behavioral attributes.” Chemosphere 184 (October 2017): 687–93. https://doi.org/10.1016/j.chemosphere.2017.06.023.Full Text
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Thomas, M. B., H. M. Stapleton, R. L. Dills, H. D. Violette, D. A. Christakis, and S. Sathyanarayana. “Demographic and dietary risk factors in relation to urinary metabolites of organophosphate flame retardants in toddlers.” Chemosphere 185 (October 2017): 918–25. https://doi.org/10.1016/j.chemosphere.2017.07.015.Full Text
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Hoffman, Kate, Amelia Lorenzo, Craig M. Butt, Stephanie C. Hammel, Brittany Bohinc Henderson, Sanziana A. Roman, Randall P. Scheri, Heather M. Stapleton, and Julie Ann Sosa. “Exposure to flame retardant chemicals and occurrence and severity of papillary thyroid cancer: A case-control study.” Environment International 107 (October 2017): 235–42. https://doi.org/10.1016/j.envint.2017.06.021.Full Text Open Access Copy
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Slotkin, Theodore A., Samantha Skavicus, Heather M. Stapleton, and Frederic J. Seidler. “Brominated and organophosphate flame retardants target different neurodevelopmental stages, characterized with embryonic neural stem cells and neuronotypic PC12 cells.” Toxicology 390 (September 2017): 32–42. https://doi.org/10.1016/j.tox.2017.08.009.Full Text
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Carignan, Courtney C., Craig M. Butt, Heather M. Stapleton, John D. Meeker, Lidia Minguez-Alarcón, Paige L. Williams, and Russ Hauser. “Influence of storage vial material on measurement of organophosphate flame retardant metabolites in urine.” Chemosphere 181 (August 2017): 440–46. https://doi.org/10.1016/j.chemosphere.2017.04.083.Full Text
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Kassotis, Christopher D., Kate Hoffman, and Heather M. Stapleton. “Characterization of Adipogenic Activity of House Dust Extracts and Semi-Volatile Indoor Contaminants in 3T3-L1 Cells.” Environmental Science & Technology 51, no. 15 (August 2017): 8735–45. https://doi.org/10.1021/acs.est.7b01788.Full Text
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Robel, Alix E., Kristin Marshall, Margaret Dickinson, David Lunderberg, Craig Butt, Graham Peaslee, Heather M. Stapleton, and Jennifer A. Field. “Closing the Mass Balance on Fluorine on Papers and Textiles.” Environmental Science & Technology 51, no. 16 (August 2017): 9022–32. https://doi.org/10.1021/acs.est.7b02080.Full Text
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Baldwin, Kylie R., Allison L. Phillips, Brian Horman, Sheryl E. Arambula, Meghan E. Rebuli, Heather M. Stapleton, and Heather B. Patisaul. “Sex Specific Placental Accumulation and Behavioral Effects of Developmental Firemaster 550 Exposure in Wistar Rats.” Scientific Reports 7, no. 1 (August 2017): 7118. https://doi.org/10.1038/s41598-017-07216-6.Full Text Open Access Copy
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Carignan, Courtney C., Lidia Mínguez-Alarcón, Craig M. Butt, Paige L. Williams, John D. Meeker, Heather M. Stapleton, Thomas L. Toth, Jennifer B. Ford, Russ Hauser, and Russ EARTH Study Team. “Urinary Concentrations of Organophosphate Flame Retardant Metabolites and Pregnancy Outcomes among Women Undergoing in Vitro Fertilization.” Environmental Health Perspectives 125, no. 8 (August 2017): 087018. https://doi.org/10.1289/ehp1021.Full Text
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Hoffman, Kate, Larisa Gearhart-Serna, Matthew Lorber, Thomas F. Webster, and Heather M. Stapleton. “Estimated tris(1,3-dichloro-2-propyl) phosphate exposure levels for US infants suggest potential health risks.” Environmental Science & Technology Letters 4, no. 8 (August 2017): 334–38. https://doi.org/10.1021/acs.estlett.7b00196.Full Text
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Castorina, Rosemary, Craig Butt, Heather M. Stapleton, Dylan Avery, Kim G. Harley, Nina Holland, Brenda Eskenazi, and Asa Bradman. “Flame retardants and their metabolites in the homes and urine of pregnant women residing in California (the CHAMACOS cohort).” Chemosphere 179 (July 2017): 159–66. https://doi.org/10.1016/j.chemosphere.2017.03.076.Full Text
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Smythe, Tristan A., Craig M. Butt, Heather M. Stapleton, Kerri Pleskach, Geemitha Ratnayake, Chae Yoon Song, Nicole Riddell, Alex Konstantinov, and Gregg T. Tomy. “Impacts of Unregulated Novel Brominated Flame Retardants on Human Liver Thyroid Deiodination and Sulfotransferation.” Environmental Science & Technology 51, no. 12 (June 2017): 7245–53. https://doi.org/10.1021/acs.est.7b01143.Full Text
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Preston, Emma V., Michael D. McClean, Birgit Claus Henn, Heather M. Stapleton, Lewis E. Braverman, Elizabeth N. Pearce, Colleen M. Makey, and Thomas F. Webster. “Associations between urinary diphenyl phosphate and thyroid function.” Environment International 101 (April 2017): 158–64. https://doi.org/10.1016/j.envint.2017.01.020.Full Text
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Hoffman, Kate, Craig M. Butt, Thomas F. Webster, Emma V. Preston, Stephanie C. Hammel, Colleen Makey, Amelia M. Lorenzo, et al. “Temporal Trends in Exposure to Organophosphate Flame Retardants in the United States.” Environ Sci Technol Lett 4, no. 3 (March 14, 2017): 112–18. https://doi.org/10.1021/acs.estlett.6b00475.Full Text Link to Item
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Cowell, Whitney J., Heather M. Stapleton, Darrell Holmes, Lehyla Calero, Catherine Tobon, Matthew Perzanowski, and Julie B. Herbstman. “Prevalence of historical and replacement brominated flame retardant chemicals in New York City homes.” Emerging Contaminants 3, no. 1 (March 2017): 32–39. https://doi.org/10.1016/j.emcon.2017.01.001.Full Text
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Hoffman, Kate, Thomas F. Webster, Andreas Sjödin, and Heather M. Stapleton. “Toddler's behavior and its impacts on exposure to polybrominated diphenyl ethers.” Journal of Exposure Science & Environmental Epidemiology 27, no. 2 (March 2017): 193–97. https://doi.org/10.1038/jes.2016.11.Full Text
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Ferguson, P Lee, and Heather M. Stapleton. “Comment on "Mutagenic Azo Dyes, Rather Than Flame Retardants, Are the Predominant Brominated Compounds in House Dust".” Environmental Science & Technology 51, no. 6 (March 2017): 3588–90. https://doi.org/10.1021/acs.est.7b00372.Full Text
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Kassotis, Christopher D., Lauren Masse, Stephanie Kim, Jennifer J. Schlezinger, Thomas F. Webster, and Heather M. Stapleton. “Characterization of Adipogenic Chemicals in Three Different Cell Culture Systems: Implications for Reproducibility Based on Cell Source and Handling.” Scientific Reports 7 (February 2017): 42104. https://doi.org/10.1038/srep42104.Full Text
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Lewis, Jessica J., John W. Hollingsworth, Ryan T. Chartier, Ellen M. Cooper, William Michael Foster, Genna L. Gomes, Peter S. Kussin, et al. “Biogas Stoves Reduce Firewood Use, Household Air Pollution, and Hospital Visits in Odisha, India.” Environ Sci Technol 51, no. 1 (January 3, 2017): 560–69. https://doi.org/10.1021/acs.est.6b02466.Full Text Link to Item
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Macaulay, Laura J., Melissa Chernick, Albert Chen, David E. Hinton, Jordan M. Bailey, Seth W. Kullman, Edward D. Levin, and Heather M. Stapleton. “Exposure to a PBDE/OH-BDE mixture alters juvenile zebrafish (Danio rerio) development.” Environ Toxicol Chem 36, no. 1 (January 2017): 36–48. https://doi.org/10.1002/etc.3535.Full Text Link to Item
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Hoffman, Kate, Amelia Lorenzo, Craig M. Butt, Linda Adair, Amy H. Herring, Heather M. Stapleton, and Julie L. Daniels. “Predictors of urinary flame retardant concentration among pregnant women.” Environment International 98 (January 2017): 96–101. https://doi.org/10.1016/j.envint.2016.10.007.Full Text
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Hoffman, Kate, Julie A. Sosa, and Heather M. Stapleton. “Do flame retardant chemicals increase the risk for thyroid dysregulation and cancer?” Current Opinion in Oncology 29, no. 1 (January 2017): 7–13. https://doi.org/10.1097/cco.0000000000000335.Full Text
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Soubry, Adelheid, Cathrine Hoyo, Craig M. Butt, Steffen Fieuws, Thomas M. Price, Susan K. Murphy, and Heather M. Stapleton. “Human exposure to flame-retardants is associated with aberrant DNA methylation at imprinted genes in sperm.” Environ Epigenet 3, no. 1 (January 2017): dvx003. https://doi.org/10.1093/eep/dvx003.Full Text Link to Item
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Leonetti, Christopher, Craig M. Butt, Kate Hoffman, Stephanie C. Hammel, Marie Lynn Miranda, and Heather M. Stapleton. “Brominated flame retardants in placental tissues: associations with infant sex and thyroid hormone endpoints.” Environmental Health : A Global Access Science Source 15, no. 1 (November 2016): 113. https://doi.org/10.1186/s12940-016-0199-8.Full Text
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Cooper, Ellen M., Gretchen Kroeger, Katherine Davis, Charlotte R. Clark, P Lee Ferguson, and Heather M. Stapleton. “Results from Screening Polyurethane Foam Based Consumer Products for Flame Retardant Chemicals: Assessing Impacts on the Change in the Furniture Flammability Standards.” Environmental Science & Technology 50, no. 19 (October 2016): 10653–60. https://doi.org/10.1021/acs.est.6b01602.Full Text Open Access Copy
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Phillips, Allison L., Albert Chen, Kylie D. Rock, Brian Horman, Heather B. Patisaul, and Heather M. Stapleton. “Editor's Highlight: Transplacental and Lactational Transfer of Firemaster® 550 Components in Dosed Wistar Rats.” Toxicological Sciences : An Official Journal of the Society of Toxicology 153, no. 2 (October 2016): 246–57. https://doi.org/10.1093/toxsci/kfw122.Full Text
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Butt, Craig M., Kate Hoffman, Albert Chen, Amelia Lorenzo, Johanna Congleton, and Heather M. Stapleton. “Regional comparison of organophosphate flame retardant (PFR) urinary metabolites and tetrabromobenzoic acid (TBBA) in mother-toddler pairs from California and New Jersey.” Environment International 94 (September 2016): 627–34. https://doi.org/10.1016/j.envint.2016.06.029.Full Text
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Carignan, Courtney C., Mingliang Fang, Heather M. Stapleton, Wendy Heiger-Bernays, Michael D. McClean, and Thomas F. Webster. “Urinary biomarkers of flame retardant exposure among collegiate U.S. gymnasts.” Environment International 94 (September 2016): 362–68. https://doi.org/10.1016/j.envint.2016.06.030.Full Text
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Hammel, Stephanie C., Kate Hoffman, Thomas F. Webster, Kim A. Anderson, and Heather M. Stapleton. “Correction to Measuring Personal Exposure to Organophosphate Flame Retardants using Silicone Wristbands and Hand Wipes.” Environmental Science & Technology 50, no. 18 (September 2016): 10291. https://doi.org/10.1021/acs.est.6b04169.Full Text
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Volz, David C., Jessica K. Leet, Albert Chen, Heather M. Stapleton, Neerja Katiyar, Rakesh Kaundal, Yang Yu, and Yinsheng Wang. “Tris(1,3-dichloro-2-propyl)phosphate Induces Genome-Wide Hypomethylation within Early Zebrafish Embryos.” Environmental Science & Technology 50, no. 18 (September 2016): 10255–63. https://doi.org/10.1021/acs.est.6b03656.Full Text
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Gomes, Genna, Peyton Ward, Amelia Lorenzo, Kate Hoffman, and Heather M. Stapleton. “Characterizing Flame Retardant Applications and Potential Human Exposure in Backpacking Tents.” Environmental Science & Technology 50, no. 10 (May 2016): 5338–45. https://doi.org/10.1021/acs.est.6b00923.Full Text
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Butt, Craig M., Marie Lynn Miranda, and Heather M. Stapleton. “Development of an analytical method to quantify PBDEs, OH-BDEs, HBCDs, 2,4,6-TBP, EH-TBB, and BEH-TEBP in human serum.” Analytical and Bioanalytical Chemistry 408, no. 10 (April 2016): 2449–59. https://doi.org/10.1007/s00216-016-9340-3.Full Text
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Hammel, Stephanie C., Kate Hoffman, Thomas F. Webster, Kim A. Anderson, and Heather M. Stapleton. “Measuring Personal Exposure to Organophosphate Flame Retardants Using Silicone Wristbands and Hand Wipes.” Environmental Science & Technology 50, no. 8 (April 2016): 4483–91. https://doi.org/10.1021/acs.est.6b00030.Full Text
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Su, Guanyong, Robert J. Letcher, Hongxia Yu, David M. Gooden, and Heather M. Stapleton. “Determination of glucuronide conjugates of hydroxyl triphenyl phosphate (OH-TPHP) metabolites in human urine and its use as a biomarker of TPHP exposure.” Chemosphere 149 (April 2016): 314–19. https://doi.org/10.1016/j.chemosphere.2016.01.114.Full Text
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Leonetti, Christopher, Craig M. Butt, Kate Hoffman, Marie Lynn Miranda, and Heather M. Stapleton. “Concentrations of polybrominated diphenyl ethers (PBDEs) and 2,4,6-tribromophenol in human placental tissues.” Environment International 88 (March 2016): 23–29. https://doi.org/10.1016/j.envint.2015.12.002.Full Text
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Lefevre, Emilie, Ellen Cooper, Heather M. Stapleton, and Claudia K. Gunsch. “Characterization and Adaptation of Anaerobic Sludge Microbial Communities Exposed to Tetrabromobisphenol A.” Plos One 11, no. 7 (January 2016): e0157622. https://doi.org/10.1371/journal.pone.0157622.Full Text
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Mendelsohn, Emma, Audrey Hagopian, Kate Hoffman, Craig M. Butt, Amelia Lorenzo, Johanna Congleton, Thomas F. Webster, and Heather M. Stapleton. “Nail polish as a source of exposure to triphenyl phosphate.” Environment International 86 (January 2016): 45–51. https://doi.org/10.1016/j.envint.2015.10.005.Full Text
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Czaplicki, L. M., E. Cooper, P. L. Ferguson, H. M. Stapleton, R. Vilgalys, and C. K. Gunsch. “A New Perspective on Sustainable Soil Remediation-Case Study Suggests Novel Fungal Genera Could Facilitate in situ Biodegradation of Hazardous Contaminants.” Remediation (New York, N.Y.) 26, no. 2 (January 2016): 59–72. https://doi.org/10.1002/rem.21458.Full Text
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Hoffman, Kate, Craig M. Butt, Albert Chen, Alexander T. Limkakeng, and Heather M. Stapleton. “High Exposure to Organophosphate Flame Retardants in Infants: Associations with Baby Products.” Environ Sci Technol 49, no. 24 (December 15, 2015): 14554–59. https://doi.org/10.1021/acs.est.5b03577.Full Text Link to Item
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Miranda, Marie Lynn, Rebecca Anthopolos, Amy Wolkin, and Heather M. Stapleton. “Associations of birth outcomes with maternal polybrominated diphenyl ethers and thyroid hormones during pregnancy.” Environment International 85 (December 2015): 244–53. https://doi.org/10.1016/j.envint.2015.09.015.Full Text
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Macaulay, Laura J., Albert Chen, Kylie D. Rock, Laura V. Dishaw, Wu Dong, David E. Hinton, and Heather M. Stapleton. “Developmental toxicity of the PBDE metabolite 6-OH-BDE-47 in zebrafish and the potential role of thyroid receptor β.” Aquatic Toxicology (Amsterdam, Netherlands) 168 (November 2015): 38–47. https://doi.org/10.1016/j.aquatox.2015.09.007.Full Text
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Maley, A. M., K. A. Falk, L. Hoover, E. B. Earlywine, M. D. Seymour, P. A. Deyoung, A. Blum, H. M. Stapleton, and G. F. Peaslee. “Detection of halogenated flame retardants in polyurethane foam by particle induced X-ray emission.” Nuclear Instruments and Methods in Physics Research, Section B: Beam Interactions With Materials and Atoms 358 (September 1, 2015): 21–25. https://doi.org/10.1016/j.nimb.2015.05.006.Full Text
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Fang, Mingliang, Thomas F. Webster, and Heather M. Stapleton. “Effect-Directed Analysis of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) Ligands in Indoor Dust.” Environmental Science & Technology 49, no. 16 (August 2015): 10065–73. https://doi.org/10.1021/acs.est.5b01524.Full Text
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Fang, Mingliang, Thomas F. Webster, and Heather M. Stapleton. “Activation of Human Peroxisome Proliferator-Activated Nuclear Receptors (PPARγ1) by Semi-Volatile Compounds (SVOCs) and Chemical Mixtures in Indoor Dust.” Environmental Science & Technology 49, no. 16 (August 2015): 10057–64. https://doi.org/10.1021/acs.est.5b01523.Full Text
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Scanlan, Leona D., Alexandre V. Loguinov, Quincy Teng, Philipp Antczak, Kathleen P. Dailey, Daniel T. Nowinski, Jonah Kornbluh, et al. “Gene transcription, metabolite and lipid profiling in eco-indicator daphnia magna indicate diverse mechanisms of toxicity by legacy and emerging flame-retardants.” Environmental Science & Technology 49, no. 12 (June 2015): 7400–7410. https://doi.org/10.1021/acs.est.5b00977.Full Text
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Roberts, Simon C., Antonio C. Bianco, and Heather M. Stapleton. “Disruption of type 2 iodothyronine deiodinase activity in cultured human glial cells by polybrominated diphenyl ethers.” Chemical Research in Toxicology 28, no. 6 (June 2015): 1265–74. https://doi.org/10.1021/acs.chemrestox.5b00072.Full Text
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Davis, Elizabeth F., Claudia K. Gunsch, and Heather M. Stapleton. “Fate of flame retardants and the antimicrobial agent triclosan in planted and unplanted biosolid-amended soils.” Environmental Toxicology and Chemistry 34, no. 5 (May 2015): 968–76. https://doi.org/10.1002/etc.2854.Full Text
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Su, G., R. J. Letcher, D. Crump, D. M. Gooden, and H. M. Stapleton. “In vitro metabolism of the flame retardant triphenyl phosphate in chicken embryonic hepatocytes and the importance of the hydroxylation pathway.” Environmental Science and Technology Letters 2, no. 4 (April 14, 2015): 100–104. https://doi.org/10.1021/acs.estlett.5b00041.Full Text
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Isales, Gregory M., Rachel A. Hipszer, Tara D. Raftery, Albert Chen, Heather M. Stapleton, and David C. Volz. “Triphenyl phosphate-induced developmental toxicity in zebrafish: potential role of the retinoic acid receptor.” Aquatic Toxicology (Amsterdam, Netherlands) 161 (April 2015): 221–30. https://doi.org/10.1016/j.aquatox.2015.02.009.Full Text
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Fang, Mingliang, Thomas F. Webster, P Lee Ferguson, and Heather M. Stapleton. “Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust.” Environmental Health Perspectives 123, no. 2 (February 2015): 166–72. https://doi.org/10.1289/ehp.1408522.Full Text
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Hoffman, Kate, Stavros Garantziotis, Linda S. Birnbaum, and Heather M. Stapleton. “Monitoring indoor exposure to organophosphate flame retardants: hand wipes and house dust.” Environmental Health Perspectives 123, no. 2 (February 2015): 160–65. https://doi.org/10.1289/ehp.1408669.Full Text
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Fang, M., T. F. Webster, P. L. Ferguson, and H. M. Stapleton. “Characterizing the peroxisome proliferator-activated receptor (PPARγ) ligand binding potential of several major flame retardants, their metabolites, and chemical mixtures in house dust.” Environmental Health Perspectives 123, no. 2 (January 1, 2015): 166–72. https://doi.org/10.1289/ehp.1408522.Full Text
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Freitag, A. R., L. A. R. Thayer, C. Leonetti, H. M. Stapleton, and H. J. Hamlin. “Effects of elevated nitrate on endocrine function in Atlantic salmon, Salmo salar.” Aquaculture 436 (January 1, 2015): 8–12. https://doi.org/10.1016/j.aquaculture.2014.10.041.Full Text
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McIntyre, Rebecca L., Heidi L. Kenerson, Savitha Subramanian, Shari A. Wang, Machiko Kazami, Heather M. Stapleton, and Raymond S. Yeung. “Polybrominated diphenyl ether congener, BDE-47, impairs insulin sensitivity in mice with liver-specific Pten deficiency.” Bmc Obesity 2 (January 2015): 3. https://doi.org/10.1186/s40608-014-0031-3.Full Text
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Macaulay, Laura J., Jordan M. Bailey, Edward D. Levin, and Heather M. Stapleton. “Persisting effects of a PBDE metabolite, 6-OH-BDE-47, on larval and juvenile zebrafish swimming behavior.” Neurotoxicol Teratol 52, no. Pt B (2015): 119–26. https://doi.org/10.1016/j.ntt.2015.05.002.Full Text Link to Item
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Dishaw, Laura V., Deborah L. Hunter, Beth Padnos, Stephanie Padilla, and Heather M. Stapleton. “Developmental exposure to organophosphate flame retardants elicits overt toxicity and alters behavior in early life stage zebrafish (Danio rerio).” Toxicological Sciences : An Official Journal of the Society of Toxicology 142, no. 2 (December 2014): 445–54. https://doi.org/10.1093/toxsci/kfu194.Full Text
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Dishaw, Laura V., Laura J. Macaulay, Simon C. Roberts, and Heather M. Stapleton. “Exposures, mechanisms, and impacts of endocrine-active flame retardants.” Current Opinion in Pharmacology 19 (December 2014): 125–33. https://doi.org/10.1016/j.coph.2014.09.018.Full Text
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Fang, Mingliang, Gordon J. Getzinger, Ellen M. Cooper, Bryan W. Clark, Lindsey V. T. Garner, Richard T. Di Giulio, P Lee Ferguson, and Heather M. Stapleton. “Effect-directed analysis of Elizabeth River porewater: developmental toxicity in zebrafish (Danio rerio).” Environmental Toxicology and Chemistry 33, no. 12 (December 2014): 2767–74. https://doi.org/10.1002/etc.2738.Full Text
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Stapleton, Heather M., John Misenheimer, Kate Hoffman, and Thomas F. Webster. “Flame retardant associations between children's handwipes and house dust.” Chemosphere 116 (December 2014): 54–60. https://doi.org/10.1016/j.chemosphere.2013.12.100.Full Text
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Pillai, Hari K., Mingliang Fang, Dmitri Beglov, Dima Kozakov, Sandor Vajda, Heather M. Stapleton, Thomas F. Webster, and Jennifer J. Schlezinger. “Ligand binding and activation of PPARγ by Firemaster® 550: effects on adipogenesis and osteogenesis in vitro.” Environmental Health Perspectives 122, no. 11 (November 2014): 1225–32. https://doi.org/10.1289/ehp.1408111.Full Text
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Fang, Mingliang, and Heather M. Stapleton. “Evaluating the bioaccessibility of flame retardants in house dust using an in vitro Tenax bead-assisted sorptive physiologically based method.” Environmental Science & Technology 48, no. 22 (November 2014): 13323–30. https://doi.org/10.1021/es503918m.Full Text
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Holzem, R. M., H. M. Stapleton, and C. K. Gunsch. “Response to comment on "Determining the ecological impacts of organic contaminants in biosolids using a high-throughput colorimetric denitrification assay: a case study with antimicrobial agents".” Environmental Science & Technology 48, no. 20 (October 2014): 12470–71. https://doi.org/10.1021/es5036305.Full Text
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Butt, Craig M., Johanna Congleton, Kate Hoffman, Mingliang Fang, and Heather M. Stapleton. “Metabolites of organophosphate flame retardants and 2-ethylhexyl tetrabromobenzoate in urine from paired mothers and toddlers.” Environmental Science & Technology 48, no. 17 (September 2014): 10432–38. https://doi.org/10.1021/es5025299.Full Text
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Hoffman, Kate, Mingliang Fang, Brian Horman, Heather B. Patisaul, Stavros Garantziotis, Linda S. Birnbaum, and Heather M. Stapleton. “Urinary tetrabromobenzoic acid (TBBA) as a biomarker of exposure to the flame retardant mixture Firemaster® 550.” Environmental Health Perspectives 122, no. 9 (September 2014): 963–69. https://doi.org/10.1289/ehp.1308028.Full Text
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Martin, Negin P., Ezequiel Marron Fernandez de Velasco, Fengxia Mizuno, Erica L. Scappini, Bernd Gloss, Christian Erxleben, Jason G. Williams, Heather M. Stapleton, Saverio Gentile, and David L. Armstrong. “A rapid cytoplasmic mechanism for PI3 kinase regulation by the nuclear thyroid hormone receptor, TRβ, and genetic evidence for its role in the maturation of mouse hippocampal synapses in vivo.” Endocrinology 155, no. 9 (September 2014): 3713–24. https://doi.org/10.1210/en.2013-2058.Full Text
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Belcher, Scott M., Clifford J. Cookman, Heather B. Patisaul, and Heather M. Stapleton. “In vitro assessment of human nuclear hormone receptor activity and cytotoxicity of the flame retardant mixture FM 550 and its triarylphosphate and brominated components.” Toxicology Letters 228, no. 2 (July 2014): 93–102. https://doi.org/10.1016/j.toxlet.2014.04.017.Full Text
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Wolf, C. J., M. Fang, H. M. Stapleton, and B. D. Abbott. “Activation of Human Peroxisome Proliferator-Activated Receptor-Gamma (PPAR gamma) by House Dust Extracts.” Birth Defects Research Part a Clinical and Molecular Teratology 100, no. 5 (May 1, 2014): 393–393.Link to Item
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Hoffman, Kate, Julie L. Daniels, and Heather M. Stapleton. “Urinary metabolites of organophosphate flame retardants and their variability in pregnant women.” Environment International 63 (February 2014): 169–72. https://doi.org/10.1016/j.envint.2013.11.013.Full Text
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Keller, Alexander S., Nikhilesh P. Raju, Thomas F. Webster, and Heather M. Stapleton. “Flame Retardant Applications in Camping Tents and Potential Exposure.” Environmental Science & Technology Letters 1, no. 2 (February 2014): 152–55. https://doi.org/10.1021/ez400185y.Full Text
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Muzzio, Amanda M., Pamela D. Noyes, Heather M. Stapleton, and Sean C. Lema. “Tissue distribution and thyroid hormone effects on mRNA abundance for membrane transporters Mct8, Mct10, and organic anion-transporting polypeptides (Oatps) in a teleost fish.” Comparative Biochemistry and Physiology. Part A, Molecular & Integrative Physiology 167 (January 2014): 77–89. https://doi.org/10.1016/j.cbpa.2013.09.019.Full Text
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Noyes, P. D., and H. M. Stapleton. “PBDE flame retardants: Toxicokinetics and thyroid hormone endocrine disruption in fish.” Endocrine Disruptors 2, no. 1 (January 1, 2014): e29430-1-e29430-25. https://doi.org/10.4161/endo.29430.Full Text
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Noyes, Pamela D., Sean C. Lema, Simon C. Roberts, Ellen M. Cooper, and Heather M. Stapleton. “Rapid method for the measurement of circulating thyroid hormones in low volumes of teleost fish plasma by LC-ESI/MS/MS.” Analytical and Bioanalytical Chemistry 406, no. 3 (January 2014): 715–26. https://doi.org/10.1007/s00216-013-7528-3.Full Text
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Dong, Wu, Laura J. Macaulay, Kevin Wh Kwok, David E. Hinton, P Lee Ferguson, and Heather M. Stapleton. “The PBDE metabolite 6-OH-BDE 47 affects melanin pigmentation and THRβ MRNA expression in the eye of zebrafish embryos.” Endocrine Disruptors (Austin, Tex.) 2, no. 1 (January 2014): e969072. https://doi.org/10.4161/23273739.2014.969072.Full Text
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Holzem, R. M., H. M. Stapleton, and C. K. Gunsch. “Determining the ecological impacts of organic contaminants in biosolids using a high-throughput colorimetric denitrification assay: a case study with antimicrobial agents.” Environmental Science & Technology 48, no. 3 (January 2014): 1646–55. https://doi.org/10.1021/es404431k.Full Text
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Levin, Edward D., Marty Cauley, Joshua E. Johnson, Ellen M. Cooper, Heather M. Stapleton, P Lee Ferguson, Frederic J. Seidler, and Theodore A. Slotkin. “Prenatal dexamethasone augments the neurobehavioral teratology of chlorpyrifos: significance for maternal stress and preterm labor.” Neurotoxicol Teratol 41 (2014): 35–42. https://doi.org/10.1016/j.ntt.2013.10.004.Full Text Link to Item
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Carignan, Courtney C., Wendy Heiger-Bernays, Michael D. McClean, Simon C. Roberts, Heather M. Stapleton, Andreas Sjödin, and Thomas F. Webster. “Flame retardant exposure among collegiate United States gymnasts.” Environmental Science & Technology 47, no. 23 (December 2013): 13848–56. https://doi.org/10.1021/es4037868.Full Text
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Butt, Craig M., and Heather M. Stapleton. “Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants and halogenated phenolics.” Chemical Research in Toxicology 26, no. 11 (November 2013): 1692–1702. https://doi.org/10.1021/tx400342k.Full Text
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Meeker, John D., Ellen M. Cooper, Heather M. Stapleton, and Russ Hauser. “Exploratory analysis of urinary metabolites of phosphorus-containing flame retardants in relation to markers of male reproductive health.” Endocrine Disruptors (Austin, Tex.) 1, no. 1 (October 2013): e26306. https://doi.org/10.4161/endo.26306.Full Text
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Noyes, Pamela D., Sean C. Lema, Laura J. Macaulay, Nora K. Douglas, and Heather M. Stapleton. “Low level exposure to the flame retardant BDE-209 reduces thyroid hormone levels and disrupts thyroid signaling in fathead minnows.” Environmental Science & Technology 47, no. 17 (September 2013): 10012–21. https://doi.org/10.1021/es402650x.Full Text
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Watkins, Deborah J., Michael D. McClean, Alicia J. Fraser, Janice Weinberg, Heather M. Stapleton, and Thomas F. Webster. “Associations between PBDEs in office air, dust, and surface wipes.” Environment International 59 (September 2013): 124–32. https://doi.org/10.1016/j.envint.2013.06.001.Full Text
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Clark, Bryan W., Ellen M. Cooper, Heather M. Stapleton, and Richard T. Di Giulio. “Compound- and mixture-specific differences in resistance to polycyclic aromatic hydrocarbons and PCB-126 among Fundulus heteroclitus subpopulations throughout the Elizabeth River estuary (Virginia, USA).” Environmental Science & Technology 47, no. 18 (September 2013): 10556–66. https://doi.org/10.1021/es401604b.Full Text
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Slotkin, Theodore A., Ellen M. Cooper, Heather M. Stapleton, and Frederic J. Seidler. “Does thyroid disruption contribute to the developmental neurotoxicity of chlorpyrifos?” Environ Toxicol Pharmacol 36, no. 2 (September 2013): 284–87. https://doi.org/10.1016/j.etap.2013.04.003.Full Text Link to Item
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Lohmann, Rainer, Heather M. Stapleton, and Ronald A. Hites. “Science In TSCA Reform.” Chemical & Engineering News 91, no. 32 (August 12, 2013): 3–3.Link to Item
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Lohmann, Rainer, Heather M. Stapleton, and Ronald A. Hites. “Science should guide TSCA reform.” Environmental Science & Technology 47, no. 16 (August 2013): 8995–96. https://doi.org/10.1021/es403027y.Full Text
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Carignan, Courtney C., Michael D. McClean, Ellen M. Cooper, Deborah J. Watkins, Alicia J. Fraser, Wendy Heiger-Bernays, Heather M. Stapleton, and Thomas F. Webster. “Predictors of tris(1,3-dichloro-2-propyl) phosphate metabolite in the urine of office workers.” Environment International 55 (May 2013): 56–61. https://doi.org/10.1016/j.envint.2013.02.004.Full Text
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Dong, Wu, Laura J. Macaulay, Kevin W. H. Kwok, David E. Hinton, and Heather M. Stapleton. “Using whole mount in situ hybridization to examine thyroid hormone deiodinase expression in embryonic and larval zebrafish: a tool for examining OH-BDE toxicity to early life stages.” Aquatic Toxicology (Amsterdam, Netherlands) 132–133 (May 2013): 190–99. https://doi.org/10.1016/j.aquatox.2013.02.008.Full Text
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Fang, Mingliang, Thomas F. Webster, David Gooden, Ellen M. Cooper, Michael D. McClean, Courtney Carignan, Colleen Makey, and Heather M. Stapleton. “Investigating a novel flame retardant known as V6: measurements in baby products, house dust, and car dust.” Environmental Science & Technology 47, no. 9 (May 2013): 4449–54. https://doi.org/10.1021/es400032v.Full Text
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McGee, Sean P., Alex Konstantinov, Heather M. Stapleton, and David C. Volz. “Aryl phosphate esters within a major PentaBDE replacement product induce cardiotoxicity in developing zebrafish embryos: potential role of the aryl hydrocarbon receptor.” Toxicological Sciences : An Official Journal of the Society of Toxicology 133, no. 1 (May 2013): 144–56. https://doi.org/10.1093/toxsci/kft020.Full Text
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Meeker, John D., Ellen M. Cooper, Heather M. Stapleton, and Russ Hauser. “Urinary metabolites of organophosphate flame retardants: temporal variability and correlations with house dust concentrations.” Environmental Health Perspectives 121, no. 5 (May 2013): 580–85. https://doi.org/10.1289/ehp.1205907.Full Text
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Webster, T. F., and H. M. Stapleton. “Human exposure assessment of indoor dust: Webster and Stapleton respond.” Environmental Health Perspectives 121, no. 4 (April 1, 2013).
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Webster, Thomas F., and Heather M. Stapleton. “Human exposure assessment of indoor dust: Webster and Stapleton respond.” Environmental Health Perspectives 121, no. 4 (April 2013): A110–11. https://doi.org/10.1289/ehp.1206470r.Full Text
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Patisaul, Heather B., Simon C. Roberts, Natalie Mabrey, Katherine A. McCaffrey, Robin B. Gear, Joe Braun, Scott M. Belcher, and Heather M. Stapleton. “Accumulation and endocrine disrupting effects of the flame retardant mixture Firemaster® 550 in rats: an exploratory assessment.” Journal of Biochemical and Molecular Toxicology 27, no. 2 (February 2013): 124–36. https://doi.org/10.1002/jbt.21439.Full Text
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Allen, Joseph G., Heather M. Stapleton, Jose Vallarino, Eileen McNeely, Michael D. McClean, Stuart J. Harrad, Cassandra B. Rauert, and John D. Spengler. “Exposure to flame retardant chemicals on commercial airplanes.” Environmental Health : A Global Access Science Source 12 (February 2013): 17. https://doi.org/10.1186/1476-069x-12-17.Full Text
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Webster, T. F., H. M. Stapleton, and M. D. McClean. “Exposure to Polybrominated Diphenyl Ethers in the Indoor Environment.” Fire Technology, 2013, 1–11. https://doi.org/10.1007/s10694-013-0334-9.Full Text
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Collins, Terrence J., Cynthia de Wit, Martin J. Mulvihill, David H. Roberts, Ruthann Rudel, David Sedlak, Heather Stapleton, and Marta Venier. “OBSERVATIONS ON FLAME RETARDANTS ARTICLES.” Chemical & Engineering News 90, no. 51 (December 17, 2012): 4–5.Link to Item
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Springer, Cecilia, Edward Dere, Susan J. Hall, Elizabeth V. McDonnell, Simon C. Roberts, Craig M. Butt, Heather M. Stapleton, et al. “Rodent thyroid, liver, and fetal testis toxicity of the monoester metabolite of bis-(2-ethylhexyl) tetrabromophthalate (tbph), a novel brominated flame retardant present in indoor dust.” Environmental Health Perspectives 120, no. 12 (December 2012): 1711–19. https://doi.org/10.1289/ehp.1204932.Full Text
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Stapleton, Heather M., Smriti Sharma, Gordon Getzinger, P Lee Ferguson, Michelle Gabriel, Thomas F. Webster, and Arlene Blum. “Novel and high volume use flame retardants in US couches reflective of the 2005 PentaBDE phase out.” Environmental Science & Technology 46, no. 24 (December 2012): 13432–39. https://doi.org/10.1021/es303471d.Full Text
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Bearr, Jonathan S., Carys L. Mitchelmore, Simon C. Roberts, and Heather M. Stapleton. “Species specific differences in the in vitro metabolism of the flame retardant mixture, Firemaster® BZ-54.” Aquatic Toxicology (Amsterdam, Netherlands) 124–125 (November 2012): 41–47. https://doi.org/10.1016/j.aquatox.2012.06.006.Full Text
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McGee, Sean P., Ellen M. Cooper, Heather M. Stapleton, and David C. Volz. “Early zebrafish embryogenesis is susceptible to developmental TDCPP exposure.” Environmental Health Perspectives 120, no. 11 (November 2012): 1585–91. https://doi.org/10.1289/ehp.1205316.Full Text
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Klosterhaus, Susan L., Heather M. Stapleton, Mark J. La Guardia, and Denise J. Greig. “Brominated and chlorinated flame retardants in San Francisco Bay sediments and wildlife.” Environment International 47 (October 2012): 56–65. https://doi.org/10.1016/j.envint.2012.06.005.Full Text
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Ashley, J. T. F., M. A. Vasquez, P. Zelanko, E. McKinley, M. Schafer, L. Zaoudeh, R. Horwitz, H. M. Stapleton, and D. J. Velinsky. “Trophic transfer of polybrominated diphenyl ethers and polychlorinated biphenyls in a tidal freshwater marsh.” Chemistry and Ecology 28, no. 4 (August 1, 2012): 305–25. https://doi.org/10.1080/02757540.2012.656608.Full Text
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Roberts, Simon C., Laura J. Macaulay, and Heather M. Stapleton. “In vitro metabolism of the brominated flame retardants 2-ethylhexyl-2,3,4,5-tetrabromobenzoate (TBB) and bis(2-ethylhexyl) 2,3,4,5-tetrabromophthalate (TBPH) in human and rat tissues.” Chemical Research in Toxicology 25, no. 7 (July 2012): 1435–41. https://doi.org/10.1021/tx300086x.Full Text
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Stapleton, Heather M., Sarah Eagle, Andreas Sjödin, and Thomas F. Webster. “Serum PBDEs in a North Carolina toddler cohort: associations with handwipes, house dust, and socioeconomic variables.” Environmental Health Perspectives 120, no. 7 (July 2012): 1049–54. https://doi.org/10.1289/ehp.1104802.Full Text
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Watkins, D. J., M. D. McClean, A. J. Fraser, J. Weinberg, H. M. Stapleton, and A. Sjoedin. “Exposure to polybrominated diphenyl ethers (PBDEs) in offices.” Environnement Risques & Sante 11, no. 4 (July 1, 2012): 274–75.Link to Item
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Davis, Elizabeth F., Susan L. Klosterhaus, and Heather M. Stapleton. “Measurement of flame retardants and triclosan in municipal sewage sludge and biosolids.” Environment International 40 (April 2012): 1–7. https://doi.org/10.1016/j.envint.2011.11.008.Full Text
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Webster, T. F., and H. M. Stapleton. “Flame Retardants: Polybrominated Diphenyl Ethers and their Replacements,” March 30, 2012, 89–108. https://doi.org/10.1002/9781118184141.ch4.Full Text
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McClain, Valerie, Heather M. Stapleton, Fred Tilton, and Evan P. Gallagher. “BDE 49 and developmental toxicity in zebrafish.” Comparative Biochemistry and Physiology. Toxicology & Pharmacology : Cbp 155, no. 2 (March 2012): 253–58. https://doi.org/10.1016/j.cbpc.2011.09.004.Full Text
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Fraser, Alicia J., Thomas F. Webster, Deborah J. Watkins, Jessica W. Nelson, Heather M. Stapleton, Antonia M. Calafat, Kayoko Kato, Mahiba Shoeib, Verónica M. Vieira, and Michael D. McClean. “Polyfluorinated compounds in serum linked to indoor air in office environments.” Environmental Science & Technology 46, no. 2 (January 2012): 1209–15. https://doi.org/10.1021/es2038257.Full Text
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Johnson, P. J., H. M. Stapleton, B. Mukherjee, R. Hauser, and J. D. Meeker. “Associations between brominated flame retardants in house dust and hormone levels in men. (Accepted)” Sci Total Environ, 2012.
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McGee, S. P., E. Cooper, H. M. Stapleton, and D. Volz. “Early Zebrafish Embryogenesis Is Susceptible to Developmental TDCPP Exposure.” Environmental Health Perspectives 120, no. 11 (2012): 1586–91.
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Watkins, Deborah J., Michael D. McClean, Alicia J. Fraser, Janice Weinberg, Heather M. Stapleton, Andreas Sjödin, and Thomas F. Webster. “Impact of dust from multiple microenvironments and diet on PentaBDE body burden.” Environmental Science & Technology 46, no. 2 (January 2012): 1192–1200. https://doi.org/10.1021/es203314e.Full Text
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Buttke, D. E., A. Wolkin, H. M. Stapleton, and M. L. Miranda. “Associations between serum levels of Polybrominated Diphenyl Ether (PBDE) flame retardants and environmental and behavioral factors in pregnant women.” Journal of Exposure Science and Environmental Epidemiology, 2012.Link to Item
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Butt, Craig M., Dongli Wang, and Heather M. Stapleton. “Halogenated phenolic contaminants inhibit the in vitro activity of the thyroid-regulating deiodinases in human liver.” Toxicological Sciences : An Official Journal of the Society of Toxicology 124, no. 2 (December 2011): 339–47. https://doi.org/10.1093/toxsci/kfr117.Full Text
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Jung, Dawoon, Cole W. Matson, Leonard B. Collins, Geoff Laban, Heather M. Stapleton, John W. Bickham, James A. Swenberg, and Richard T. Di Giulio. “Genotoxicity in Atlantic killifish (Fundulus heteroclitus) from a PAH-contaminated Superfund site on the Elizabeth River, Virginia.” Ecotoxicology (London, England) 20, no. 8 (November 2011): 1890–99. https://doi.org/10.1007/s10646-011-0727-9.Full Text
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Dishaw, Laura V., Christina M. Powers, Ian T. Ryde, Simon C. Roberts, Frederic J. Seidler, Theodore A. Slotkin, and Heather M. Stapleton. “Is the PentaBDE replacement, tris (1,3-dichloro-2-propyl) phosphate (TDCPP), a developmental neurotoxicant? Studies in PC12 cells.” Toxicol Appl Pharmacol 256, no. 3 (November 1, 2011): 281–89. https://doi.org/10.1016/j.taap.2011.01.005.Full Text Link to Item
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Cooper, E. M., A. Covaci, A. L. N. van Nuijs, T. F. Webster, and H. M. Stapleton. “Analysis of the flame retardant metabolites bis(1,3-dichloro-2-propyl) phosphate (BDCPP) and diphenyl phosphate (DPP) in urine using liquid chromatography-tandem mass spectrometry.” Analytical and Bioanalytical Chemistry 401, no. 7 (October 2011): 2123–32. https://doi.org/10.1007/s00216-011-5294-7.Full Text
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Watkins, Deborah J., Michael D. McClean, Alicia J. Fraser, Janice Weinberg, Heather M. Stapleton, Andreas Sjödin, and Thomas F. Webster. “Exposure to PBDEs in the office environment: evaluating the relationships between dust, handwipes, and serum.” Environmental Health Perspectives 119, no. 9 (September 2011): 1247–52. https://doi.org/10.1289/ehp.1003271.Full Text
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Noyes, Pamela D., David E. Hinton, and Heather M. Stapleton. “Accumulation and debromination of decabromodiphenyl ether (BDE-209) in juvenile fathead minnows (Pimephales promelas) induces thyroid disruption and liver alterations.” Toxicological Sciences : An Official Journal of the Society of Toxicology 122, no. 2 (August 2011): 265–74. https://doi.org/10.1093/toxsci/kfr105.Full Text
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Stapleton, Heather M., Susan Klosterhaus, Alex Keller, P Lee Ferguson, Saskia van Bergen, Ellen Cooper, Thomas F. Webster, and Arlene Blum. “Identification of flame retardants in polyurethane foam collected from baby products.” Environmental Science & Technology 45, no. 12 (June 2011): 5323–31. https://doi.org/10.1021/es2007462.Full Text
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Roberts, Simon C., Pamela D. Noyes, Evan P. Gallagher, and Heather M. Stapleton. “Species-specific differences and structure-activity relationships in the debromination of PBDE congeners in three fish species.” Environmental Science & Technology 45, no. 5 (March 2011): 1999–2005. https://doi.org/10.1021/es103934x.Full Text
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Stapleton, H. M., S. D. Eagle, A. Sjodin, and T. F. Webster. “Serum PBDEs in US Toddlers: Associations with Hand Wipes, House Dust and Socioeconomic Variables (Submitted).” Environmental Health Perspectives, 2011.
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Stapleton, Heather M., Sarah Eagle, Rebecca Anthopolos, Amy Wolkin, and Marie Lynn Miranda. “Associations between Polybrominated Diphenyl Ether (PBDE) Flame Retardants, Phenolic Metabolites, and Thyroid Hormones during Pregnancy.” Environmental Health Perspectives 119, no. 10 (2011): 1454–59.
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Tomy, Gregg T., Vince Palace, Chris Marvin, Heather M. Stapleton, Adrian Covaci, and Stuart Harrad. “Biotransformation of HBCD in biological systems can confound temporal-trend studies.” Environmental Science & Technology 45, no. 2 (January 2011): 364–65. https://doi.org/10.1021/es1039369.Full Text
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Cooper, Ellen M., Heather M. Stapleton, Cole W. Matson, Richard T. Di Giulio, and Andrew J. Schuler. “Ultraviolet treatment and biodegradation of dibenzothiophene: Identification and toxicity of products.” Environmental Toxicology and Chemistry 29, no. 11 (November 2010): 2409–16. https://doi.org/10.1002/etc.312.Full Text
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Ashley, J. T. F., J. S. Ward, M. W. Schafer, H. M. Stapleton, and D. J. Velinsky. “Evaluating daily exposure to polychlorinated biphenyls and polybrominated diphenyl ethers in fish oil supplements.” Food Additives & Contaminants. Part A, Chemistry, Analysis, Control, Exposure & Risk Assessment 27, no. 8 (August 2010): 1177–85. https://doi.org/10.1080/19440041003793298.Full Text
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Johnson, Paula I., Heather M. Stapleton, Andreas Sjodin, and John D. Meeker. “Relationships between polybrominated diphenyl ether concentrations in house dust and serum.” Environmental Science & Technology 44, no. 14 (July 2010): 5627–32. https://doi.org/10.1021/es100697q.Full Text Open Access Copy
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Wang, Dongli, and Heather M. Stapleton. “Analysis of thyroid hormones in serum by liquid chromatography-tandem mass spectrometry.” Analytical and Bioanalytical Chemistry 397, no. 5 (July 2010): 1831–39. https://doi.org/10.1007/s00216-010-3705-9.Full Text
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Kim, Gi Beum, and Heather M. Stapleton. “PBDEs, methoxylated PBDEs and HBCDs in Japanese common squid (Todarodes pacificus) from Korean offshore waters.” Marine Pollution Bulletin 60, no. 6 (June 2010): 935–40. https://doi.org/10.1016/j.marpolbul.2010.03.025.Full Text
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Noyes, Pamela D., Shannon M. Kelly, Carys L. Mitchelmore, and Heather M. Stapleton. “Characterizing the in vitro hepatic biotransformation of the flame retardant BDE 99 by common carp.” Aquatic Toxicology (Amsterdam, Netherlands) 97, no. 2 (April 2010): 142–50. https://doi.org/10.1016/j.aquatox.2009.12.013.Full Text
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Bearr, Jonathan S., Heather M. Stapleton, and Carys L. Mitchelmore. “Accumulation and DNA damage in fathead minnows (Pimephales promelas) exposed to 2 brominated flame-retardant mixtures, Firemaster 550 and Firemaster BZ-54.” Environmental Toxicology and Chemistry 29, no. 3 (March 2010): 722–29. https://doi.org/10.1002/etc.94.Full Text
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Meeker, John D., and Heather M. Stapleton. “House dust concentrations of organophosphate flame retardants in relation to hormone levels and semen quality parameters.” Environmental Health Perspectives 118, no. 3 (March 2010): 318–23. https://doi.org/10.1289/ehp.0901332.Full Text
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Stapleton, Heather M., Susan Klosterhaus, Sarah Eagle, Jennifer Fuh, John D. Meeker, Arlene Blum, and Thomas F. Webster. “Detection of organophosphate flame retardants in furniture foam and U.S. house dust.” Environmental Science & Technology 43, no. 19 (October 2009): 7490–95. https://doi.org/10.1021/es9014019.Full Text
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Stapleton, Heather M., and Elizabeth F. Davis. “Response to "Comment on 'Photodegradation Pathways of Nonabrominated Diphenyl Ethers, 2-Ethylhexyltetrabromobenzoate, and Di(2-ethylhexyl)tetrabromophthalate: Identifying Potential Markers of Photodegradation'".” Environmental Science & Technology 43, no. 20 (October 2009): 7994. https://doi.org/10.1021/es902576n.Full Text
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Davis, Elizabeth F., and Heather M. Stapleton. “Photodegradation pathways of nonabrominated diphenyl ethers, 2-ethylhexyltetrabromobenzoate and di(2-ethylhexyl)tetrabromophthalate: identifying potential markers of photodegradation.” Environmental Science & Technology 43, no. 15 (August 2009): 5739–46. https://doi.org/10.1021/es901019w.Full Text
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Browne, Eva P., Heather M. Stapleton, Shannon M. Kelly, Susan C. Tilton, and Evan P. Gallagher. “In vitro hepatic metabolism of 2,2',4,4',5-pentabromodiphenyl ether (BDE 99) in Chinook salmon (Onchorhynchus tshawytscha).” Aquatic Toxicology (Amsterdam, Netherlands) 92, no. 4 (May 2009): 281–87. https://doi.org/10.1016/j.aquatox.2009.02.017.Full Text
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Webster, Thomas F., Stuart Harrad, James R. Millette, R David Holbrook, Jeffrey M. Davis, Heather M. Stapleton, Joseph G. Allen, et al. “Identifying transfer mechanisms and sources of decabromodiphenyl ether (BDE 209) in indoor environments using environmental forensic microscopy.” Environmental Science & Technology 43, no. 9 (May 2009): 3067–72. https://doi.org/10.1021/es803139w.Full Text
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Stapleton, Heather M., Shannon M. Kelly, Ruoting Pei, Robert J. Letcher, and Claudia Gunsch. “Metabolism of polybrominated diphenyl ethers (PBDEs) by human hepatocytes in vitro.” Environmental Health Perspectives 117, no. 2 (February 2009): 197–202. https://doi.org/10.1289/ehp.11807.Full Text
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Stapleton, H. M., S. M. Kelly, J. G. Allen, D. J. Watkins, W. J. Heiger-Bernays, M. D. McClean, T. F. Webster, A. Konstantinov, and S. Klosterhaus. “Response to comment on "Altemate and new brominated flame retardants detected in U.S. house dust".” Environmental Science and Technology 42, no. 24 (December 15, 2008): 9455–56. https://doi.org/10.1021/es8026192.Full Text
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Allen, Joseph G., Michael D. McClean, Heather M. Stapleton, and Thomas F. Webster. “Critical factors in assessing exposure to PBDEs via house dust.” Environment International 34, no. 8 (November 2008): 1085–91. https://doi.org/10.1016/j.envint.2008.03.006.Full Text
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Stapleton, Heather M., Joseph G. Allen, Shannon M. Kelly, Alex Konstantinov, Susan Klosterhaus, Deborah Watkins, Michael D. McClean, and Thomas F. Webster. “Alternate and new brominated flame retardants detected in U.S. house dust.” Environmental Science & Technology 42, no. 18 (September 2008): 6910–16. https://doi.org/10.1021/es801070p.Full Text
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Allen, Joseph G., Michael D. McClean, Heather M. Stapleton, and Thomas F. Webster. “Linking PBDEs in house dust to consumer products using X-ray fluorescence.” Environmental Science & Technology 42, no. 11 (June 2008): 4222–28. https://doi.org/10.1021/es702964a.Full Text
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Stapleton, Heather M., Andreas Sjödin, Richard S. Jones, Sara Niehüser, Yalin Zhang, and Donald G. Patterson. “Serum levels of polybrominated diphenyl ethers (PBDEs) in foam recyclers and carpet installers working in the United States.” Environmental Science & Technology 42, no. 9 (May 2008): 3453–58. https://doi.org/10.1021/es7028813.Full Text
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Stapleton, Heather M., Shannon M. Kelly, Joseph G. Allen, Michael D. Mcclean, and Thomas F. Webster. “Measurement of polybrominated diphenyl ethers on hand wipes: estimating exposure from hand-to-mouth contact.” Environmental Science & Technology 42, no. 9 (May 2008): 3329–34. https://doi.org/10.1021/es7029625.Full Text
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Huwe, Janice K., Heldur Hakk, David J. Smith, Janet J. Diliberto, Vicki Richardson, Heather M. Stapleton, and Linda S. Birnbaum. “Comparative absorption and bioaccumulation of polybrominated diphenyl ethers following ingestion via dust and oil in male rats.” Environmental Science & Technology 42, no. 7 (April 2008): 2694–2700. https://doi.org/10.1021/es702644k.Full Text
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Stapleton, Heather M., and Nathan G. Dodder. “Photodegradation of decabromodiphenyl ether in house dust by natural sunlight.” Environmental Toxicology and Chemistry 27, no. 2 (February 2008): 306–12. https://doi.org/10.1897/07-301r.1.Full Text
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Allen, J. G., M. D. McClean, H. M. Stapleton, and T. F. Webster. “Longitudinal Analysis of Polybrominated Diphenyl Ethers (PBDEs) in Household Microenvironments: Characterization of Dust and Relationship to Indoor Air.” Environment International 34, no. 8 (2008): 1085–91.
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Stapleton, H. M., A. Sjodin, R. S. Jones, S. Niehauser, Y. Zhang, and D. G. Patterson. “Serum PBDE Levels in Occupationally Exposed Individuals in the United States.” Environ Sci & Technol 42, no. 9 (2008): 3453–58.
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Stapleton, H. M., S. M. Kelly, J. G. Allen, M. D. McClean, and T. F. Webster. “Measurement of Polybrominated Diphenyl Ethers on Hand Wipes: Estimating Exposure from Hand to Mouth Contact.” Environ Sci & Technol 49, no. 9 (2008): 3329–34.
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Benedict, Rae T., Heather M. Stapleton, Robert J. Letcher, and Carys L. Mitchelmore. “Debromination of polybrominated diphenyl ether-99 (BDE-99) in carp (Cyprinus carpio) microflora and microsomes.” Chemosphere 69, no. 6 (October 2007): 987–93. https://doi.org/10.1016/j.chemosphere.2007.05.010.Full Text
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Schantz, Michele M., Jennifer M. Keller, Stefan Leigh, Donald G. Patterson, Katherine E. Sharpless, Andreas Sjödin, Heather M. Stapleton, Robert Swarthout, Wayman E. Turner, and Stephen A. Wise. “Certification of SRM 1589a PCBs, pesticides, PBDEs, and dioxins/furans in human serum.” Analytical and Bioanalytical Chemistry 389, no. 4 (October 2007): 1201–8. https://doi.org/10.1007/s00216-007-1519-1.Full Text
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Schantz, B. M. M., J. M. Keller, J. R. Kucklick, D. L. Poster, H. M. Stapleton, S. S. V. Pol, and S. A. Wise. “New standard reference material (srm) 2585: Organic contaminants in house dust to support exposure assessment measurements.” American Laboratory 39, no. 15 (August 1, 2007): 22–28.
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Allen, Joseph G., Michael D. McClean, Heather M. Stapleton, Jessica W. Nelson, and Thomas F. Webster. “Personal exposure to polybrominated diphenyl ethers (PBDEs) in residential indoor air.” Environmental Science & Technology 41, no. 13 (July 2007): 4574–79. https://doi.org/10.1021/es0703170.Full Text
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Ashley, J. T. F., D. Libero, E. Halscheid, L. Zaoudeh, and H. M. Stapleton. “Polybrominated diphenyl ethers in American eels (Anguilla rostrata) from the Delaware River, USA.” Bulletin of Environmental Contamination and Toxicology 79, no. 1 (July 2007): 99–103. https://doi.org/10.1007/s00128-007-9090-1.Full Text
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Stapleton, Heather M., Jennifer M. Keller, Michele M. Schantz, John R. Kucklick, Stefan D. Leigh, and Stephen A. Wise. “Determination of polybrominated diphenyl ethers in environmental standard reference materials.” Analytical and Bioanalytical Chemistry 387, no. 7 (April 2007): 2365–79. https://doi.org/10.1007/s00216-006-1054-5.Full Text
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Stapleton, Heather M. “Instrumental methods and challenges in quantifying polybrominated diphenyl ethers in environmental extracts: a review.” Analytical and Bioanalytical Chemistry 386, no. 4 (October 2006): 807–17. https://doi.org/10.1007/s00216-006-0400-y.Full Text
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Stapleton, Heather M., Brian Brazil, R David Holbrook, Carys L. Mitchelmore, Rae Benedict, Alex Konstantinov, and Dave Potter. “In vivo and in vitro debromination of decabromodiphenyl ether (BDE 209) by juvenile rainbow trout and common carp.” Environmental Science & Technology 40, no. 15 (August 2006): 4653–58. https://doi.org/10.1021/es060573x.Full Text
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Stapleton, H. M., N. G. Dodder, J. R. Kucklick, C. M. Reddy, M. M. Schantz, P. R. Becker, F. Gulland, B. J. Porter, and S. A. Wise. “Determination of HBCD, PBDEs and MeO-BDEs in California sea lions (Zalophus californianus) stranded between 1993 and 2003.” Marine Pollution Bulletin 52, no. 5 (May 2006): 522–31. https://doi.org/10.1016/j.marpolbul.2005.09.045.Full Text
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Stapleton, Heather M., Tom Harner, Mahiba Shoeib, Jennifer M. Keller, Michele M. Schantz, Stefan D. Leigh, and Stephen A. Wise. “Determination of polybrominated diphenyl ethers in indoor dust standard reference materials.” Analytical and Bioanalytical Chemistry 384, no. 3 (February 2006): 791–800. https://doi.org/10.1007/s00216-005-0227-y.Full Text
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Stapleton, Heather M., Nathan G. Dodder, John H. Offenberg, Michele M. Schantz, and Stephen A. Wise. “Polybrominated diphenyl ethers in house dust and clothes dryer lint.” Environmental Science & Technology 39, no. 4 (February 2005): 925–31. https://doi.org/10.1021/es0486824.Full Text
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Tuerk, Karen J. S., John R. Kucklick, Paul R. Becker, Heather M. Stapleton, and Joel E. Baker. “Persistent organic pollutants in two dolphin species with focus on toxaphene and polybrominated diphenyl ethers.” Environmental Science & Technology 39, no. 3 (February 2005): 692–98. https://doi.org/10.1021/es0487675.Full Text
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Stapleton, Heather M., Robert J. Letcher, Juliana Li, and Joel E. Baker. “Dietary accumulation and metabolism of polybrominated diphenyl ethers by juvenile carp (Cyprinus carpio).” Environmental Toxicology and Chemistry 23, no. 8 (August 2004): 1939–46. https://doi.org/10.1897/03-462.Full Text
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Stapleton, Heather M., Robert J. Letcher, and Joel E. Baker. “Debromination of polybrominated diphenyl ether congeners BDE 99 and BDE 183 in the intestinal tract of the common carp (Cyprinus carpio).” Environmental Science & Technology 38, no. 4 (February 2004): 1054–61. https://doi.org/10.1021/es0348804.Full Text
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Stapleton, Heather M., Mehran Alaee, Robert J. Letcher, and Joel E. Baker. “Debromination of the flame retardant decabromodiphenyl ether by juvenile carp (Cyprinus carpio) following dietary exposure.” Environmental Science & Technology 38, no. 1 (January 2004): 112–19. https://doi.org/10.1021/es034746j.Full Text
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Hale, Robert C., Mehran Alaee, Jon B. Manchester-Neesvig, Heather M. Stapleton, and Michael G. Ikonomou. “Polybrominated diphenyl ether flame retardants in the North American environment.” Environment International 29, no. 6 (September 2003): 771–79. https://doi.org/10.1016/s0160-4120(03)00113-2.Full Text
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Stapleton, H. M., and J. E. Baker. “Comparing polybrominated diphenyl ether and polychlorinated biphenyl bioaccumulation in a food web in Grand Traverse Bay, Lake Michigan.” Archives of Environmental Contamination and Toxicology 45, no. 2 (August 2003): 227–34. https://doi.org/10.1007/s00244-003-0165-7.Full Text
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Ashley, J. T. F., A. Moore, H. M. Stapleton, D. J. Velinsky, and M. P. Wilhelm. “Sedimentary nonylphenol contamination in an urbanized, industrialized segment of the Delaware River estuary, USA.” Bulletin of Environmental Contamination and Toxicology 70, no. 5 (May 2003): 978–84. https://doi.org/10.1007/s00128-003-0078-1.Full Text
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Stapleton, H. M., J. Skubinna, and J. E. Baker. “Seasonal dynamics of PCB and toxaphene bioaccumulation within a Lake Michigan food web.” Journal of Great Lakes Research 28, no. 1 (January 1, 2002): 52–64. https://doi.org/10.1016/S0380-1330(02)70562-5.Full Text
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Stapleton, H. M., R. J. Letcher, and J. E. Baker. “Metabolism of PCBs by the deepwater sculpin (Myoxocephalus thompsoni).” Environmental Science & Technology 35, no. 24 (December 2001): 4747–52. https://doi.org/10.1021/es015571l.Full Text
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Schneider, A. R., H. M. Stapleton, J. Cornwell, and J. E. Baker. “Recent declines in PAH, PCB, and toxaphene levels in the northern Great Lakes as determined from high resolution sediment cores.” Environmental Science & Technology 35, no. 19 (October 2001): 3809–15. https://doi.org/10.1021/es002044d.Full Text
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Stapleton, H. M., C. Masterson, J. Skubinna, P. Ostrom, N. E. Ostrom, and J. E. Baker. “Accumulation of atmospheric and sedimentary PCBs and toxaphene in a Lake Michigan food web.” Environmental Science & Technology 35, no. 16 (August 2001): 3287–93. https://doi.org/10.1021/es0019225.Full Text
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Stapleton, H., and A. O’Grady. “Isolation techniques fur high-resolution data-acquisition systems.” Edn 46, no. 3 (February 1, 2001): 113-+.Link to Item
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Stapleton, H. M., R. J. Letcher, and J. E. Baker. “Metabolism of highly chlorinated PCBs by a Lake Michigan fish.” Environ. Sci. Technol. 35, no. 24 (2001): 4747–52.
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Stapleton, H. “Measure temperature in remote locations.” Edn 45, no. 21 (October 12, 2000): 194–194.Link to Item
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Conference Papers
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Curras-Collazo, Margarita, Elena Kozlova, Heather Stapleton, Gwen Gonzalez, Bhuvana D. Chinthirla, and Julia M. Krum. “Sex‐Dependent Metabolic Syndrome Phenotype Produced By Developmental Exposure to Indoor Flame Retardants.” In The Faseb Journal, 34:1–1. Wiley, 2020. https://doi.org/10.1096/fasebj.2020.34.s1.07444.Full Text
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Ruis, M. T., and H. M. Stapleton. “The Placenta: A Mediator of Thyroid Hormone Disruption Following Gestational Exposure to Flame Retardants.” In International Journal of Toxicology, 39:52–52. SAGE PUBLICATIONS INC, 2020.Link to Item
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Blake, B. E., H. Cope, S. Hall, R. Keys, B. Mahler, J. Mccord, B. Scott, et al. “Gestational Exposure to Perfluorooctanoic Acid (PFOA) or Its Replacement GenX Induces Adverse Pregnancy Outcomes and Disrupts the Placenta.” In Birth Defects Research, 112:823–823, 2020.Link to Item
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Hoffman, Kate, and Heather M. Stapleton. “Papillary thyroid cancer clusters in North Carolina 1997-2017.” In Cancer Prevention Research, 13:36–36, 2020.Link to Item
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Chanti-Ketterl, Marianne, brenda Plassman, Christine Parks, Nicholas Herkert, Julie Fleenor, Sharon Zhang, and Heather Stapleton. “Validating Silicone Wristbands to Measure Pesticide Exposures Among Older Adults -- Proof-of-Concept Study,” 2019. https://doi.org/10.1093/geroni/igz038.3298.Full Text Link to Item
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Phillips, Allison L., and Heather M. Stapleton. “Inhibition of Human Liver Carboxylesterase (hCE1) by Organophosphate Ester Flame Retardants and Plasticizers: Implications for Pharmacotherapy.” In Toxicological Sciences : An Official Journal of the Society of Toxicology, 171:396–405, 2019. https://doi.org/10.1093/toxsci/kfz149.Full Text
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Ruis, M. T., K. R. Baldwin, S. M. Hall, B. Horman, H. Patisaul, and H. M. Stapleton. “Tissue-Specific Accumulation of PBDEs in the Placenta and Effects on Thyroid Regulation.” In International Journal of Toxicology, 38:42–43. SAGE PUBLICATIONS INC, 2019.Link to Item
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Abdulrahim, Jawan W., Heather M. Stapleton, Maggie Nguyen, Lydia C. Kwee, Olga Ilkayeva, Cherry M. Beasley, John W. Stanifer, and Svati H. Shah. “Metabolites Associated With Per- and Polyfluoroalkyl Substance (PFAS) Levels in an Ethnically Diverse Underserved At-Risk Rural Population.” In Circulation, Vol. 140, 2019.Link to Item
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Mitchell, C. A., S. Dasgupta, S. Zhang, H. Stapleton, and D. C. Volz. “Disruption of Nuclear Receptor Signaling Alters Triphenyl Phosphate-Induced Cardiotoxicity in Zebrafish Embryos.” In Birth Defects Research, 110:785–785. WILEY, 2018.Link to Item
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Phillips, A., and H. Stapleton. “Inhibition of Carboxylesterase Enzymes by Isopropylated Triarylphosphate Ester Flame Retardants: Implications for Pharmacotherapy and Cardiovascular Disease.” In International Journal of Toxicology, 37:70–70. SAGE PUBLICATIONS INC, 2018.Link to Item
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Dishaw, Laura, and Heather Stapleton. “Halogenated organophosphate flame retardants: Developmental neurotoxicity and possible mechanisms of action.” In Neurotoxicology and Teratology, 49:106–106. Elsevier BV, 2015. https://doi.org/10.1016/j.ntt.2015.04.026.Full Text
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Leonetti, Christopher, Thomas Neufeld, Craig Butt, and Heather Stapleton. “Inhibition of thyroid hormone sulfotransferase activity by brominated flame retardants in a human choriocarcinoma cell line, BeWo.” In Abstracts of Papers of the American Chemical Society, Vol. 249. AMER CHEMICAL SOC, 2015.Link to Item
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Bailey, Jordan, Anthony Oliveri, Heather Stapleton, and Edward Levin. “Behavioral effects of short-term exposure to Firemaster 550.” In Neurotoxicology and Teratology, 37:86–86. Elsevier BV, 2013. https://doi.org/10.1016/j.ntt.2013.03.046.Full Text
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Muzzio, A. M., P. D. Noyes, H. M. Stapleton, and S. C. Lema. “The Organic Anion Transporting Protein (OATP) Family in a Teleost Fish Model.” In Integrative and Comparative Biology, 53:E340–E340. OXFORD UNIV PRESS INC, 2013.Link to Item
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Webster, Thomas, Heather Stapleton, and Michael McClean. “Exposure to Polybrominated Diphenyl Ethers in Indoor Environments.” In Epidemiology, 22:S117–S117. Ovid Technologies (Wolters Kluwer Health), 2011. https://doi.org/10.1097/01.ede.0000392027.72377.2c.Full Text
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Johnson, Paula I., Heather M. Stapleton, Russ Hauser, and John D. Meeker. “Relationships Between Brominated Flame Retardant Concentrations in House Dust and Serum Hormone Levels in Men.” In Epidemiology, 20:S162–63. Ovid Technologies (Wolters Kluwer Health), 2009. https://doi.org/10.1097/01.ede.0000362553.06292.cd.Full Text
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Allen, J. G., M. D. McClean, H. M. Stapleton, and T. F. Webster. “Televisions as Sources of DecaBDE in House Dust.” In Epidemiology, 19:S76–S76. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Huwe, J. K., H. Hakk, H. M. Stapleton, and L. S. Birnbaum. “Tissue Distribution of Polybrominated Diphenyl Ethers in Rats Following Oral Exposure and the Relationship to Body Burdens.” In Epidemiology, 19:S76–S76. LIPPINCOTT WILLIAMS & WILKINS, 2008.Link to Item
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Allen, J., M. Mcclean, H. Stapleton, J. Nelson, G. Sanchez, A. Fraser, and T. Webster. “PBDE Levels in Indoor Air and Dust Collected From US Urban Residences.” In Epidemiology, 17:S375–S375. Ovid Technologies (Wolters Kluwer Health), 2006. https://doi.org/10.1097/00001648-200611001-00997.Full Text
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Schantz, M. M., J. R. Kucklick, D. Poster, H. M. Stapleton, and S. A. Wise. “Certification of a house dust standard reference material for determination of organic contaminants.” In Abstracts of Papers of the American Chemical Society, 230:U209–U209. AMER CHEMICAL SOC, 2005.Link to Item
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Letcher, R. J., M. McKinney, H. M. Stapleton, J. Verreault, G. Gabrielsen, F. Scipione, S. G. Chu, and K. Valters. “Biotransformation and persistent metabolites of organohalogen contaminants in model marine and aquatic wildlife and populations.” In Drug Metabolism Reviews, 36:25–25. TAYLOR & FRANCIS INC, 2004.Link to Item
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- Teaching & Mentoring
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Recent Courses
- CEE 563: Chemical Fate of Organic Compounds 2023
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- CEE 563: Chemical Fate of Organic Compounds 2022
- ENVIRON 360: Environmental Health: Pollutant Chemistry and Toxicology 2022
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Outreach & Engaged Scholarship
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