Scholars@Duke
Hui-Jie Lee

Hui-Jie Lee

Statistical Scientist
Biostatistics & Bioinformatics
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Selected Publications

Medication Payments by Insurers and Patients for the Treatment of Metastatic Castrate-Resistant Prostate Cancer.

Journal Article JCO Oncol Pract · April 2023 PURPOSE: The implications of high prices for cancer drugs on health care costs and patients' financial burdens are a growing concern. Patients with metastatic castrate-resistant prostate cancer (mCRPC) are often candidates for multiple first-line systemic ... Full text Link to item Cite

Evaluation of alpelisib-induced hyperglycemia prophylaxis and associated risk factors in PIK3CA-mutated hormone-receptor positive, human epidermal growth factor-2 negative advanced breast cancer.

Journal Article Breast Cancer Res Treat · January 2023 PURPOSE: SOLAR-1 investigated alpelisib-fulvestrant (ALP + FLV) in patients with HR + /HER2-, PIK3CA-mutated advanced breast cancer and demonstrated a clinically significant increase in all-grade and grade (G) 3-4 hyperglycemia (HG) compared to placebo-ful ... Full text Link to item Cite

Outcomes With a Mobile Digital Health Platform for Patients Undergoing Spine Surgery: Retrospective Analysis.

Journal Article JMIR Perioper Med · October 26, 2022 BACKGROUND: Digital health solutions have been shown to enhance outcomes for individuals with chronic medical illnesses, but few have been validated for surgical patients. The digital health platform ManageMySurgery (MMS) has been validated for spine surge ... Full text Link to item Cite

Receipt and Sharing of Information to Improve Knowledge About Living Donor Kidney Transplant among Transplant Candidates with Advanced Chronic Kidney Disease.

Journal Article Prog Transplant · September 2022 Introduction: Knowledge about living donor kidney transplant (LDKT) is associated with greater access. Yet, little is known about factors associated with high living donor transplant knowledge. Research Questions: Is receipt of LDKT information from health ... Full text Link to item Cite

Effect of Initial Anticoagulation Targets on Bleeding and Thrombotic Complications for Patients With Acute Respiratory Distress Syndrome Receiving Extracorporeal Membrane Oxygenation.

Journal Article J Cardiothorac Vasc Anesth · September 2022 OBJECTIVE: To evaluate the effect of anticoagulation targets and intensity on bleeding events, thrombotic events, and transfusion requirements in patients with acute respiratory distress syndrome (ARDS) receiving venovenous extracorporeal membrane oxygenat ... Full text Link to item Cite

Predicting postoperative complications in pediatric surgery: A novel pediatric comorbidity index.

Journal Article J Pediatr Urol · June 2022 INTRODUCTION/BACKGROUND: Comorbidity-driven surgical risk assessment is essential for informed patient counseling, risk-stratification, and outcomes-based health-services research. Existing mortality-focused comorbidity indices have had mixed success at ri ... Full text Link to item Cite

Pedigree-based and phylogenetic methods support surprising patterns of mutation rate and spectrum in the gray mouse lemur.

Journal Article Heredity · August 2021 Mutations are the raw material on which evolution acts, and knowledge of their frequency and genomic distribution is crucial for understanding how evolution operates at both long and short timescales. At present, the rate and spectrum of de novo mutations ... Full text Cite

Decreasing tracheostomy placement in hospitalized pediatric patients with subglottic stenosis - Kids' Inpatient Database (KID) analysis.

Journal Article Int J Pediatr Otorhinolaryngol · July 2021 OBJECTIVES: We aimed to assess procedural trends for tracheostomy placement in the management of children with subglottic stenosis. We hypothesize that with increased use of less invasive airway interventions for subglottic stenosis, tracheostomy may be pe ... Full text Link to item Cite

Outcomes and Health Care Resource Utilization of Adult Bacterial Meningitis in the United States.

Journal Article Neurol Clin Pract · April 2021 OBJECTIVE: To examine the longitudinal health care resource utilization, in-hospital mortality, and incidence of downstream complications of bacterial meningitis in the United States. METHODS: Using IBM MarketScan, we retrieved data on adult patients with ... Full text Link to item Cite

Prevalence and risk factors of burnout in community pharmacists.

Journal Article Journal of the American Pharmacists Association : JAPhA · March 2021 ObjectivesThis study aimed to identify the prevalence and risk factors for occupational burnout in community pharmacists.MethodsCommunity pharmacists were solicited through a professional network e-mail Listserv to complete an anonymous, ... Full text Cite

Paediatric bacterial meningitis in the USA: outcomes and healthcare resource utilization of nosocomial versus community-acquired infection.

Journal Article J Med Microbiol · January 2021 Introduction. Paediatric bacterial meningitis remains a costly disease, both financially and clinically.Hypothesis/Gap Statement. Previous epidemiological and cost studies of bacterial meningitis (BM) have largely focused on adult populations or single pat ... Full text Link to item Cite

Empirical use of causal inference methods to evaluate survival differences in a real-world registry vs those found in randomized clinical trials.

Journal Article Stat Med · September 30, 2020 With heighted interest in causal inference based on real-world evidence, this empirical study sought to understand differences between the results of observational analyses and long-term randomized clinical trials. We hypothesized that patients deemed "eli ... Full text Link to item Cite

Variability in donor organ offer acceptance and lung transplantation survival.

Journal Article J Heart Lung Transplant · April 2020 BACKGROUND: Lung transplantation offers a survival benefit for patients with end-stage lung disease. When suitable donors are identified, centers must accept or decline the offer for a matched candidate on their waitlist. The degree to which variability in ... Full text Link to item Cite

Current trends and 30-day surgical outcomes for thyroglossal duct cyst excision in children.

Journal Article Int J Pediatr Otorhinolaryngol · January 2020 OBJECTIVE: Identify current trends, adverse events, and clinical predictors in children treated with thyroglossal duct cyst surgery. METHODS: Cross-sectional analysis using American College of Surgeons (ACS) National Surgical Quality Improvement Program® ( ... Full text Link to item Cite

Discharge summary training curriculum: a novel approach to training medical students how to write effective discharge summaries.

Journal Article Clin Teach · October 2019 BACKGROUND: Resident physicians at teaching hospitals write many discharge summaries (DCSs), but receive little formal training or feedback. Poor DCS quality poses a potential patient safety risk. METHODS: We developed a curriculum to train fourth-year med ... Full text Link to item Cite

Does influenza vaccination or RSV prophylaxis impact resource utilization for children after the diagnosis of airway disorders?

Journal Article Int J Pediatr Otorhinolaryngol · May 2019 OBJECTIVE: Quantify the rates influenza vaccination and RSV prophylaxis for children with airway stenosis and/or other disorders and assess impact on resource utilization. METHODS: This was a retrospective study with data extracted from Duke Enterprise Dat ... Full text Link to item Cite