Journal ArticleJCO Oncol Pract · April 2023
PURPOSE: The implications of high prices for cancer drugs on health care costs and patients' financial burdens are a growing concern. Patients with metastatic castrate-resistant prostate cancer (mCRPC) are often candidates for multiple first-line systemic ...
Full textLink to itemCite
Journal ArticleBreast Cancer Res Treat · January 2023
PURPOSE: SOLAR-1 investigated alpelisib-fulvestrant (ALP + FLV) in patients with HR + /HER2-, PIK3CA-mutated advanced breast cancer and demonstrated a clinically significant increase in all-grade and grade (G) 3-4 hyperglycemia (HG) compared to placebo-ful ...
Full textLink to itemCite
Journal ArticleJMIR Perioper Med · October 26, 2022
BACKGROUND: Digital health solutions have been shown to enhance outcomes for individuals with chronic medical illnesses, but few have been validated for surgical patients. The digital health platform ManageMySurgery (MMS) has been validated for spine surge ...
Full textLink to itemCite
Journal ArticleProg Transplant · September 2022
Introduction: Knowledge about living donor kidney transplant (LDKT) is associated with greater access. Yet, little is known about factors associated with high living donor transplant knowledge. Research Questions: Is receipt of LDKT information from health ...
Full textLink to itemCite
Journal ArticleJ Cardiothorac Vasc Anesth · September 2022
OBJECTIVE: To evaluate the effect of anticoagulation targets and intensity on bleeding events, thrombotic events, and transfusion requirements in patients with acute respiratory distress syndrome (ARDS) receiving venovenous extracorporeal membrane oxygenat ...
Full textLink to itemCite
Journal ArticleJ Pediatr Urol · June 2022
INTRODUCTION/BACKGROUND: Comorbidity-driven surgical risk assessment is essential for informed patient counseling, risk-stratification, and outcomes-based health-services research. Existing mortality-focused comorbidity indices have had mixed success at ri ...
Full textLink to itemCite
Journal ArticleHeredity · August 2021
Mutations are the raw material on which evolution acts, and knowledge of their frequency and genomic distribution is crucial for understanding how evolution operates at both long and short timescales. At present, the rate and spectrum of de novo mutations ...
Full textCite
Journal ArticleInt J Pediatr Otorhinolaryngol · July 2021
OBJECTIVES: We aimed to assess procedural trends for tracheostomy placement in the management of children with subglottic stenosis. We hypothesize that with increased use of less invasive airway interventions for subglottic stenosis, tracheostomy may be pe ...
Full textLink to itemCite
Journal ArticleNeurol Clin Pract · April 2021
OBJECTIVE: To examine the longitudinal health care resource utilization, in-hospital mortality, and incidence of downstream complications of bacterial meningitis in the United States. METHODS: Using IBM MarketScan, we retrieved data on adult patients with ...
Full textLink to itemCite
Journal ArticleJournal of the American Pharmacists Association : JAPhA · March 2021
ObjectivesThis study aimed to identify the prevalence and risk factors for occupational burnout in community pharmacists.MethodsCommunity pharmacists were solicited through a professional network e-mail Listserv to complete an anonymous, ...
Full textCite
Journal ArticleJ Med Microbiol · January 2021
Introduction. Paediatric bacterial meningitis remains a costly disease, both financially and clinically.Hypothesis/Gap Statement. Previous epidemiological and cost studies of bacterial meningitis (BM) have largely focused on adult populations or single pat ...
Full textLink to itemCite
Journal ArticleStat Med · September 30, 2020
With heighted interest in causal inference based on real-world evidence, this empirical study sought to understand differences between the results of observational analyses and long-term randomized clinical trials. We hypothesized that patients deemed "eli ...
Full textLink to itemCite
Journal ArticleJ Heart Lung Transplant · April 2020
BACKGROUND: Lung transplantation offers a survival benefit for patients with end-stage lung disease. When suitable donors are identified, centers must accept or decline the offer for a matched candidate on their waitlist. The degree to which variability in ...
Full textLink to itemCite
Journal ArticleInt J Pediatr Otorhinolaryngol · January 2020
OBJECTIVE: Identify current trends, adverse events, and clinical predictors in children treated with thyroglossal duct cyst surgery. METHODS: Cross-sectional analysis using American College of Surgeons (ACS) National Surgical Quality Improvement Program® ( ...
Full textLink to itemCite
Journal ArticleClin Teach · October 2019
BACKGROUND: Resident physicians at teaching hospitals write many discharge summaries (DCSs), but receive little formal training or feedback. Poor DCS quality poses a potential patient safety risk. METHODS: We developed a curriculum to train fourth-year med ...
Full textLink to itemCite
Journal ArticleInt J Pediatr Otorhinolaryngol · May 2019
OBJECTIVE: Quantify the rates influenza vaccination and RSV prophylaxis for children with airway stenosis and/or other disorders and assess impact on resource utilization. METHODS: This was a retrospective study with data extracted from Duke Enterprise Dat ...
Full textLink to itemCite