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Huihua Li

Assistant Professor of Pathology
Pathology
40 Duke Medicine Circle, Rm 214M, Durham, NC 27710
40 Duke Medicine Circle, Rm 214M, Durham, NC 27710

Current Appointments & Affiliations


Assistant Professor of Pathology · 2023 - Present Pathology, Clinical Science Departments

In the News


Published July 18, 2023
Dr. Huihua Li Joins Faculty

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Recent Publications


Clinical significance of C4d positivity within the first month after heart transplantation in detecting antibody-mediated rejection on endomyocardial biopsies.

Journal Article Cardiovasc Pathol · September 20, 2025 BACKGROUND: The pathologic definition for antibody-mediated rejection (AMR) includes both histopathological and immunopathological components. C4d is the most validated diagnostic marker for immunopathologic AMR; however, the clinical significance of early ... Full text Link to item Cite

Mechanisms of Cardiac Implantable Electronic Device Interference With the Tricuspid Valve Apparatus.

Journal Article Am J Cardiol · September 1, 2025 Cardiac implantable electronic devices (CIEDs) have been implicated in the development of tricuspid valve (TV) dysfunction. However, the mechanisms of dysfunction are not well characterized. We sought to define the prevalence, location and mechanisms of CI ... Full text Link to item Cite

Complement factor H targeting antibody GT103 in refractory non-small cell lung cancer: a phase 1b dose escalation trial.

Journal Article Nat Commun · January 2, 2025 GT103 is a first-in-class, fully human, IgG3 monoclonal antibody targeting complement factor H that kills tumor cells and promotes anti-cancer immunity in preclinical models. We conducted a first-in-human phase 1b study dose escalation trial of GT103 in re ... Full text Open Access Link to item Cite
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Recent Grants


CXCR2 expression in lung neuroendocrine neoplasms

ResearchPrincipal Investigator · Awarded by Lung Cancer Initiative of North Carolina · 2024 - 2025

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Education, Training & Certifications


Central South University, Xiangya School of Medicine (China) · 2010 Ph.D.
University of South China (China) · 2003 M.D.