Huiman Xie Barnhart | Scholars@Duke

Huiman Xie Barnhart
Professor of Biostatistics and Bioinformatics

My research interests include both statistical methodology and disease-specific clinical research biostatistics. My statistical research areas include methods for assessing reliability/agreement between methods or raters, evaluating performance of new medical diagnostic tests, missing data, correlated categorical data and methods for clinical trials. My collaborative research include the following clinical areas: cardiovascular imaging, radiology imaging, cardiovascular disease, renal disease, reproductive medicine, Parkinson disease, and aging.

Current Appointments & Affiliations

Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2009
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2003

Contact Information

7th Floor North Pavilion, Durham, NC 27710
Duke Box 3850, Durham, NC 27710
huiman.barnhart@duke.edu (919) 668-8403

Background
Education, Training, & Certifications
- Associate Professor (with Tenure), Biostatistics, Emory University 1998 - 2003
- Assistant Professor (Tenure Track), Biostatistics, Emory University 1992 - 1998
- Grad Student Researcher, Epid. Data Coord. Ctr., Epidemiology, University of Pittsburgh 1989 - 1992
- Ph.D., University of Pittsburgh 1992
- Teaching Assistant, Mathematics And Statistics, University of Pittsburgh 1986 - 1989
- M.A., University of Pittsburgh 1988
Duke Appointment History
- Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2006 - 2009
- Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2004 - 2006
- Instructor, Temporary of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2003 - 2004
Research
Selected Grants
- Coordinating Center for the Drug Induced Liver Injury Network (DILIN) awarded by National Institutes of Health 2003 - 2023
- Coordinating Center for the Drug Induced Liver Injury Network (DILIN)- Supplement awarded by National Institute of Diabetes and Digestive and Kidney Diseases 2003 - 2023
- 2/2 A comparison of individualized vs. weight based protocols to treat vaso-occlusive episodes in Sickle Cell Disease (COMPARE VOE) awarded by National Institutes of Health 2018 - 2022
- Duke Training Grant in Digestive Diseases and Nutrition awarded by National Institutes of Health 1988 - 2021
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2019
- AASLD Innovation Fund awarded by University of North Carolina - Chapel Hill 2017 - 2019
- PACTTE-Partnership for Anemia: Clinical and Translational Trials in the Elderly awarded by National Institutes of Health 2009 - 2019
- Coordinating Center for the Drug Induced Liver Injury Network (DILIN) awarded by National Institutes of Health 2008 - 2018
- Simultaneous Emission and Transmission Mammotomography awarded by National Institutes of Health 2002 - 2014
- Analysis of associations between anemia correction in CKD and mortality: CHOIR awarded by National Institutes of Health 2008 - 2012
- Nitric Oxide Metabolism in Statin-treated Pediatric SLE awarded by National Institutes of Health 2003 - 2011
- Blood pressure, endothelial cell dysfunction and outcomes in kidney disease awarded by National Institutes of Health 2008
- Cooperative Multi-Center Reproductive Medicine Network awarded by National Institutes of Health 2000 - 2008
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Daubert, MA, Adams, K, Yow, E, Barnhart, HX, Douglas, PS, Rimmer, S, Norris, C, Cooper, L, Leifer, E, Desvigne-Nickens, P, Anstrom, K, Fiuzat, M, Ezekowitz, J, Mark, DB, O'Connor, CM, Januzzi, J, and Felker, GM. "NT-proBNP Goal Achievement Is Associated With Significant Reverse Remodeling and Improved Clinical Outcomes in HFrEF." Jacc. Heart Failure 7, no. 2 (February 2019): 158-168. Full Text
  - Fontana, RJ, Cirulli, ET, Gu, J, Kleiner, D, Ostrov, D, Phillips, E, Schutte, R, Barnhart, H, Chalasani, N, Watkins, PB, and Hoofnagle, JH. "The role of HLA-A*33:01 in patients with cholestatic hepatitis attributed to terbinafine." Journal of Hepatology 69, no. 6 (December 2018): 1317-1325. Full Text
  - Li, Z, Wang, X, Barnhart, HX, and Wang, Y. "Working With Statisticians in Clinical Research." Stroke 49, no. 11 (November 2018): e311-e313. Full Text Link to Item
  - Diamantidis, CJ, Bosworth, HB, Oakes, MM, Davenport, CA, Pendergast, JF, Patel, S, Moaddeb, J, Barnhart, HX, Merrill, PD, Baloch, K, Crowley, MJ, and Patel, UD. "Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD) study: Protocol and baseline characteristics of a randomized controlled trial." Contemporary Clinical Trials 69 (June 2018): 28-39. Full Text
  - Khouri, MG, Ky, B, Dunn, G, Plappert, T, Englefield, V, Rabineau, D, Yow, E, Barnhart, HX, St John Sutton, M, and Douglas, PS. "Echocardiography Core Laboratory Reproducibility of Cardiac Safety Assessments in Cardio-Oncology." Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography 31, no. 3 (March 2018): 361-371.e3. Full Text
  - Tyson, CC, Barnhart, H, Sapp, S, Poon, V, Lin, P-H, and Svetkey, LP. "Ambulatory blood pressure in the dash diet trial: Effects of race and albuminuria." Journal of Clinical Hypertension (Greenwich, Conn.) 20, no. 2 (February 2018): 308-314. Full Text
  - Ahmad, J, Rossi, S, Rodgers, SK, Ghabril, M, Fontana, RJ, Stolz, A, Hayashi, PH, Barnhart, H, Kleiner, DE, and Bjornsson, ES. "Sclerosing Cholangitis–Like Changes on Magnetic Resonance Cholangiography in Patients With Drug Induced Liver Injury(Accepted)." Clinical Gastroenterology and Hepatology (January 1, 2018). Full Text
  - Bonkovsky, HL, Barnhart, HX, Foureau, DM, Steuerwald, N, Lee, WM, Gu, J, Fontana, RJ, Hayashi, PJ, Chalasani, N, Navarro, VM, Odin, J, Stolz, A, Watkins, PB, Serrano, J, and US Drug-Induced Liver Injury Network and the Acute Liver Failure Study Group, . "Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group." Plos One 13, no. 10 (January 2018): e0206389-null. Full Text
  - Ahmad, J, Odin, JA, Hayashi, PH, Chalasani, N, Fontana, RJ, Barnhart, H, Cirulli, ET, Kleiner, DE, and Hoofnagle, JH. "Identification and Characterization of Fenofibrate-Induced Liver Injury." Digestive diseases and sciences 62, no. 12 (December 2017): 3596-3604. Full Text
  - Daubert, MA, Yow, E, Dunn, G, Marchev, S, Barnhart, H, Douglas, PS, O'Connor, C, Goldstein, S, Udelson, JE, and Sabbah, HN. "Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide." Circulation. Heart Failure 10, no. 12 (December 2017). Full Text
  - Zullig, LL, Diamantidis, CJ, Bosworth, HB, Bhapkar, MV, Barnhart, H, Oakes, MM, Pendergast, JF, Miller, JJ, and Patel, UD. "Racial differences in nocturnal dipping status in diabetic kidney disease: Results from the STOP-DKD (Simultaneous Risk Factor Control Using Telehealth to Slow Progression of Diabetic Kidney Disease) study." Journal of Clinical Hypertension (Greenwich, Conn.) 19, no. 12 (December 2017): 1327-1335. Full Text
  - Suzuki, A, Barnhart, H, Gu, J, Bonkovsky, HL, Tillmann, HL, Fontana, RJ, Kleiner, DE, and Drug-induced Liver Injury Network (DILIN), . "Associations of gender and a proxy of female menopausal status with histological features of drug-induced liver injury." Liver International : Official Journal of the International Association for the Study of the Liver 37, no. 11 (November 2017): 1723-1730. Full Text
  - Hayashi, PH, Rockey, DC, Fontana, RJ, Tillmann, HL, Kaplowitz, N, Barnhart, HX, Gu, J, Chalasani, NP, Reddy, KR, Sherker, AH, Hoofnagle, JH, and Drug-Induced Liver Injury Network (DILIN) Investigators, . "Death and liver transplantation within 2 years of onset of drug-induced liver injury." Hepatology (Baltimore, Md.) 66, no. 4 (October 2017): 1275-1285. Full Text
  - Chalasani, N, Reddy, KRK, Fontana, RJ, Barnhart, H, Gu, J, Hayashi, PH, Ahmad, J, Stolz, A, Navarro, V, and Hoofnagle, JH. "Idiosyncratic Drug Induced Liver Injury in African-Americans Is Associated With Greater Morbidity and Mortality Compared to Caucasians." The American Journal of Gastroenterology 112, no. 9 (September 2017): 1382-1388. Full Text
  - Wang, X, Wang, Y, Patel, UD, Barnhart, HX, Li, Z, Li, H, Wang, C, Zhao, X, Liu, L, Wang, Y, and Laskowitz, DT. "Comparison of Associations of Reduced Estimated Glomerular Filtration Rate With Stroke Outcomes Between Hypertension and No Hypertension." Stroke 48, no. 6 (June 2017): 1691-1694. Full Text
  - Bonkovsky, HL, Kleiner, DE, Gu, J, Odin, JA, Russo, MW, Navarro, VM, Fontana, RJ, Ghabril, MS, Barnhart, H, Hoofnagle, JH, and U.S. Drug Induced Liver Injury Network Investigators, . "Clinical presentations and outcomes of bile duct loss caused by drugs and herbal and dietary supplements." Hepatology (Baltimore, Md.) 65, no. 4 (April 2017): 1267-1277. Full Text
  - Nicoletti, P, Aithal, GP, Bjornsson, ES, Andrade, RJ, Sawle, A, Arrese, M, Barnhart, HX, Bondon-Guitton, E, Hayashi, PH, Bessone, F, Carvajal, A, Cascorbi, I, Cirulli, ET, Chalasani, N, Conforti, A, Coulthard, SA, Daly, MJ, Day, CP, Dillon, JF, Fontana, RJ, Grove, JI, Hallberg, P, Hernández, N, Ibáñez, L, Kullak-Ublick, GA, Laitinen, T, Larrey, D, Lucena, MI, Maitland-van der Zee, AH, Martin, JH, Molokhia, M, Pirmohamed, M, Powell, EE, Qin, S, Serrano, J, Stephens, C, Stolz, A, Wadelius, M, Watkins, PB, Floratos, A, Shen, Y, Nelson, MR, Urban, TJ, Daly, AK, International Drug-Induced Liver Injury Consortium, Drug-Induced Liver Injury Network Investigators, and and International Serious Adverse Events Consortium, . "Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study." Gastroenterology 152, no. 5 (April 2017): 1078-1089. Full Text
  - Barnhart, HX, Yow, E, Crowley, AL, Daubert, MA, Rabineau, D, Bigelow, R, Pencina, M, and Douglas, PS. "Choice of agreement indices for assessing and improving measurement reproducibility in a core laboratory setting." Statistical methods in medical research 25, no. 6 (December 2016): 2939-2958. Full Text
  - Crowley, AL, Yow, E, Barnhart, HX, Daubert, MA, Bigelow, R, Sullivan, DC, Pencina, M, and Douglas, PS. "Critical Review of Current Approaches for Echocardiographic Reproducibility and Reliability Assessment in Clinical Research." Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography 29, no. 12 (December 2016): 1144-1154.e7. (Review) Full Text
  - Pan, Y, and Barnhart, HX. "Methods for assessing the reliability of quality of life based on SF-36." Statistics in medicine 35, no. 30 (December 2016): 5656-5665. Full Text
  - Barnhart, HX. "Assessing agreement with relative area under the coverage probability curve." Statistics in medicine 35, no. 18 (August 2016): 3153-3165. Full Text
  - Tyson, CC, Lin, P-H, Corsino, L, Batch, BC, Allen, J, Sapp, S, Barnhart, H, Nwankwo, C, Burroughs, J, and Svetkey, LP. "Short-term effects of the DASH diet in adults with moderate chronic kidney disease: a pilot feeding study." Clinical Kidney Journal 9, no. 4 (August 2016): 592-598. Full Text Open Access Copy
  - deLemos, AS, Ghabril, M, Rockey, DC, Gu, J, Barnhart, HX, Fontana, RJ, Kleiner, DE, Bonkovsky, HL, and Drug-Induced Liver Injury Network (DILIN), . "Amoxicillin-Clavulanate-Induced Liver Injury." Digestive Diseases and Sciences 61, no. 8 (August 2016): 2406-2416. Full Text
  - Lauridsen, TK, Selton-Suty, C, Tong, S, Afonso, L, Cecchi, E, Park, L, Yow, E, Barnhart, HX, Paré, C, Samad, Z, Levine, D, Peterson, G, Stancoven, AB, Johansson, MC, Dickerman, S, Tamin, S, Habib, G, Douglas, PS, Bruun, NE, and Crowley, AL. "Echocardiographic agreement in the diagnostic evaluation for infective endocarditis." The international journal of cardiovascular imaging 32, no. 7 (July 2016): 1041-1051. Full Text
  - Burke, CJ, Didolkar, MM, Barnhart, HX, and Vinson, EN. "The use of routine non density calibrated clinical computed tomography data as a potentially useful screening tool for identifying patients with osteoporosis." Clinical cases in mineral and bone metabolism : the official journal of the Italian Society of Osteoporosis, Mineral Metabolism, and Skeletal Diseases 13, no. 2 (May 2016): 135-140. Full Text
  - Obuchowski, NA, Buckler, A, Kinahan, P, Chen-Mayer, H, Petrick, N, Barboriak, DP, Bullen, J, Barnhart, H, and Sullivan, DC. "Statistical Issues in Testing Conformance with the Quantitative Imaging Biomarker Alliance (QIBA) Profile Claims." Academic radiology 23, no. 4 (April 2016): 496-506. (Review) Full Text
  - Lin, L, Pan, Y, Hedayat, AS, Barnhart, HX, and Haber, M. "A simulation study of nonparametric total deviation index as a measure of agreement based on quantile regression." Journal of biopharmaceutical statistics 26, no. 5 (January 2016): 937-950. Full Text
  - Lyles, RH, Kupper, LL, Barnhart, HX, and Martin, SL. "Numeric score-based conditional and overall change-in-status indices for ordered categorical data." Statistics in medicine 34, no. 27 (November 2015): 3622-3636. Full Text
  - Fontana, RJ, Hayashi, PH, Barnhart, H, Kleiner, DE, Reddy, KR, Chalasani, N, Lee, WM, Stolz, A, Phillips, T, Serrano, J, Watkins, PB, and DILIN Investigators, . "Persistent liver biochemistry abnormalities are more common in older patients and those with cholestatic drug induced liver injury." The American Journal of Gastroenterology 110, no. 10 (October 2015): 1450-1459. Full Text
  - Uller, W, and Alomari, AI. "Abernethy Malformation." Radiographics : a review publication of the Radiological Society of North America, Inc 35, no. 5 (September 2015): 1623-. (Letter) Full Text
  - Hayes, MG, Urbanek, M, Ehrmann, DA, Armstrong, LL, Lee, JY, Sisk, R, Karaderi, T, Barber, TM, McCarthy, MI, Franks, S, Lindgren, CM, Welt, CK, Diamanti-Kandarakis, E, Panidis, D, Goodarzi, MO, Azziz, R, Zhang, Y, James, RG, Olivier, M, Kissebah, AH, Reproductive Medicine Network, , Stener-Victorin, E, Legro, RS, and Dunaif, A. "Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations." Nature Communications 6 (August 18, 2015): 7502-null. Full Text
  - Daubert, MA, Yow, E, Barnhart, HX, Rabineau, D, Crowley, AL, and Douglas, PS. "Quality Improvement Implementation: Improving Reproducibility in the Echocardiography Laboratory." Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 28, no. 8 (August 2015): 959-968. Full Text
  - Daubert, MA, Yow, E, Barnhart, HX, Rabineau, D, Crowley, AL, and Douglas, PS. "Quality Improvement Implementation: Improving Reproducibility in the Echocardiography Laboratory." Journal of the American Society of Echocardiography 28, no. 8 (August 1, 2015): 959-968. Full Text
  - Chalasani, N, Bonkovsky, HL, Fontana, R, Lee, W, Stolz, A, Talwalkar, J, Reddy, KR, Watkins, PB, Navarro, V, Barnhart, H, Gu, J, Serrano, J, and United States Drug Induced Liver Injury Network, . "Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study." Gastroenterology 148, no. 7 (June 2015): 1340-52.e7. Full Text
  - Forsha, D, Risum, N, Rajagopal, S, Dolgner, S, Hornik, C, Barnhart, H, Kisslo, J, and Barker, P. "The influence of angle of insonation and target depth on speckle-tracking strain." Journal of the American Society of Echocardiography : Official Publication of the American Society of Echocardiography 28, no. 5 (May 2015): 580-586. Full Text
  - Hayashi, PH, Barnhart, HX, Fontana, RJ, Chalasani, N, Davern, TJ, Talwalkar, JA, Reddy, KR, Stolz, AA, Hoofnagle, JH, and Rockey, DC. "Reliability of causality assessment for drug, herbal and dietary supplement hepatotoxicity in the Drug-Induced Liver Injury Network (DILIN)." Liver International : Official Journal of the International Association for the Study of the Liver 35, no. 5 (May 2015): 1623-1632. Full Text
  - Kessler, LG, Barnhart, HX, Buckler, AJ, Choudhury, KR, Kondratovich, MV, Toledano, A, Guimaraes, AR, Filice, R, Zhang, Z, Sullivan, DC, and QIBA Terminology Working Group, . "The emerging science of quantitative imaging biomarkers terminology and definitions for scientific studies and regulatory submissions." Statistical Methods in Medical Research 24, no. 1 (February 2015): 9-26. Full Text Open Access Copy
  - Obuchowski, NA, Barnhart, HX, Buckler, AJ, Pennello, G, Wang, X-F, Kalpathy-Cramer, J, Kim, HJG, Reeves, AP, and Case Example Working Group, . "Statistical issues in the comparison of quantitative imaging biomarker algorithms using pulmonary nodule volume as an example." Statistical Methods in Medical Research 24, no. 1 (February 2015): 107-140. Full Text
  - Obuchowski, NA, Reeves, AP, Huang, EP, Wang, X-F, Buckler, AJ, Kim, HJG, Barnhart, HX, Jackson, EF, Giger, ML, Pennello, G, Toledano, AY, Kalpathy-Cramer, J, Apanasovich, TV, Kinahan, PE, Myers, KJ, Goldgof, DB, Barboriak, DP, Gillies, RJ, Schwartz, LH, Sullivan, DC, and Algorithm Comparison Working Group, . "Quantitative imaging biomarkers: a review of statistical methods for computer algorithm comparisons." Statistical Methods in Medical Research 24, no. 1 (February 2015): 68-106. (Review) Full Text
  - Price, E, Artz, AS, Barnhart, H, Sapp, S, Chelune, G, Ershler, WB, Walston, JD, Gordeuk, VR, Berger, NA, Reuben, D, Prchal, J, Rao, SV, Roy, CN, Supiano, MA, Schrier, SL, and Cohen, HJ. "A prospective randomized wait list control trial of intravenous iron sucrose in older adults with unexplained anemia and serum ferritin 20-200 ng/mL." Blood Cells, Molecules & Diseases 53, no. 4 (December 2014): 221-230. Full Text
  - Price, E, Artz, AS, Barnhart, H, Sapp, S, Chelune, G, Ershler, WB, Walston, JD, Gordeuk, VR, Berger, NA, Reuben, D, Prchal, J, Rao, SV, Roy, CN, Supiano, MA, Schrier, SL, and Cohen, HJ. "A prospective randomized wait list control trial of intravenous iron sucrose in older adults with unexplained anemia and serum ferritin 20-200ng/mL." Blood Cells, Molecules, and Diseases 53, no. 4 (December 1, 2014): 221-230. Full Text
  - Navarro, VJ, Barnhart, H, Bonkovsky, HL, Davern, T, Fontana, RJ, Grant, L, Reddy, KR, Seeff, LB, Serrano, J, Sherker, AH, Stolz, A, Talwalkar, J, Vega, M, and Vuppalanchi, R. "Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network." Hepatology (Baltimore, Md.) 60, no. 4 (October 2014): 1399-1408. Full Text
  - Russo, MW, Hoofnagle, JH, Gu, J, Fontana, RJ, Barnhart, H, Kleiner, DE, Chalasani, N, and Bonkovsky, HL. "Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network." Hepatology (Baltimore, Md.) 60, no. 2 (August 2014): 679-686. Full Text
  - Fontana, RJ, Hayashi, PH, Gu, J, Reddy, KR, Barnhart, H, Watkins, PB, Serrano, J, Lee, WM, Chalasani, N, Stolz, A, Davern, T, Talwakar, JA, and DILIN Network, . "Idiosyncratic drug-induced liver injury is associated with substantial morbidity and mortality within 6 months from onset." Gastroenterology 147, no. 1 (July 2014): 96-108.e4. Full Text
  - "Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein." Annals of the Rheumatic Diseases 73, no. 3 (March 1, 2014): 557-566. Full Text
  - Ardoin, SP, Schanberg, LE, Sandborg, CI, Barnhart, HX, Evans, GW, Yow, E, Mieszkalski, KL, Ilowite, NT, Eberhard, A, Imundo, LF, Kimura, Y, Levy, D, von Scheven, E, Silverman, E, Bowyer, SL, Punaro, L, Singer, NG, Sherry, DD, McCurdy, DK, Klein-Gitelman, M, Wallace, C, Silver, RM, Wagner-Weiner, L, Higgins, GC, Brunner, HI, Jung, L, Soep, JB, Reed, AM, Thompson, SD, and APPLE investigators, . "Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein." Annals of the Rheumatic Diseases 73, no. 3 (March 2014): 557-566. Full Text
  - Kleiner, DE, Chalasani, NP, Lee, WM, Fontana, RJ, Bonkovsky, HL, Watkins, PB, Hayashi, PH, Davern, TJ, Navarro, V, Reddy, R, Talwalkar, JA, Stolz, A, Gu, J, Barnhart, H, Hoofnagle, JH, and Drug-Induced Liver Injury Network (DILIN), . "Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations." Hepatology (Baltimore, Md.) 59, no. 2 (February 2014): 661-670. Full Text
  - Kleiner, DE, Chalasani, NP, Lee, WM, Fontana, RJ, Bonkovsky, HL, Watkins, PB, Hayashi, PH, Davern, TJ, Navarro, V, Reddy, R, Talwalkar, JA, Stolz, A, Gu, J, Barnhart, H, and Hoofnagle, JH. "Hepatic histological findings in suspected drug-induced liver injury: Systematic evaluation and clinical associations." Hepatology 59, no. 2 (2014): 661-670. Full Text
  - Navarro, VJ, Barnhart, H, Bonkovsky, HL, Davern, T, Fontana, RJ, Grant, L, Reddy, KR, Seeff, LB, Serrano, J, Sherker, AH, Stolz, A, Talwalkar, J, Vega, M, and Vuppalanchi, R. "Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network." Hepatology 60, no. 4 (2014): 1399-1408. Full Text
  - Chen, B, Barnhart, H, Richard, S, Robins, M, Colsher, J, and Samei, E. "Volumetric quantification of lung nodules in CT with iterative reconstruction (ASiR and MBIR)." Medical Physics 40, no. 11 (November 2013): 111902-null. Full Text
  - Navarro, VJ, Bonkovsky, HL, Hwang, S-I, Vega, M, Barnhart, H, and Serrano, J. "Catechins in dietary supplements and hepatotoxicity." Digestive Diseases and Sciences 58, no. 9 (September 2013): 2682-2690. Full Text
  - Chen, B, Marin, D, Richard, S, Husarik, D, Nelson, R, and Samei, E. "Precision of iodine quantification in hepatic CT: effects of iterative reconstruction with various imaging parameters." AJR Am J Roentgenol 200, no. 5 (May 2013): W475-W482. Full Text Link to Item
  - Chen, C-C, and Barnhart, HX. "Assessing agreement with intraclass correlation coefficient and concordance correlation coefficient for data with repeated measures." Computational Statistics & Data Analysis 60 (April 2013): 132-145. Full Text
  - Chen, C-C, and Barnhart, HX. "Assessing agreement with intraclass correlation coefficient and concordance correlation coefficient for data with repeated measures." Computational Statistics and Data Analysis 60, no. 1 (2013): 132-145. Full Text
  - McCullough, PA, Barnhart, HX, Inrig, JK, Reddan, D, Sapp, S, Patel, UD, Singh, AK, Szczech, LA, and Califf, RM. "Cardiovascular toxicity of epoetin-alfa in patients with chronic kidney disease." American Journal of Nephrology 37, no. 6 (January 2013): 549-558. Full Text
  - Navarro, VJ, Bonkovsky, HL, Hwang, S-I, Vega, M, Barnhart, H, and Serrano, J. "Catechins in dietary supplements and hepatotoxicity." Digestive Diseases and Sciences 58, no. 9 (2013): 2682-2690. Full Text
  - Steuerwald, NM, Foureau, DM, Norton, HJ, Zhou, J, Parsons, JC, Chalasani, N, Fontana, RJ, Watkins, PB, Lee, WM, Reddy, KR, Stolz, A, Talwalkar, J, Davern, T, Saha, D, Bell, LN, Barnhart, H, Gu, J, Serrano, J, and Bonkovsky, HL. "Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance." PloS one 8, no. 12 (January 2013): e81974-. Full Text
  - Wang, Z, Sundy, JS, Foss, CM, Barnhart, HX, Palmer, SM, Allgood, SD, Trudeau, E, Alexander, KM, and Levesque, MC. "Racial differences in the association of CD14 polymorphisms with serum total IgE levels and allergen skin test reactivity." Journal of Asthma and Allergy 6 (January 2013): 81-92. Full Text
  - Daubert, MA, Barnhart, HX, Yow, E, Rabineau, D, and Douglas, PS. "A Practical Approach to Quality Assurance Implementation in Clinical Echocardiographic Laboratories." CIRCULATION 126, no. 21 (November 20, 2012). Link to Item
  - Inrig, JK, Barnhart, HX, Reddan, D, Patel, UD, Sapp, S, Califf, RM, Singh, AK, and Szczech, LA. "Effect of hemoglobin target on progression of kidney disease: a secondary analysis of the CHOIR (Correction of Hemoglobin and Outcomes in Renal Insufficiency) trial." American Journal of Kidney Diseases : the Official Journal of the National Kidney Foundation 60, no. 3 (September 2012): 390-401. Full Text
  - Inrig, JK, Sapp, S, Barnhart, H, Patel, UD, Reddan, D, Singh, A, Califf, RM, and Szczech, L. "Impact of higher hemoglobin targets on blood pressure and clinical outcomes: a secondary analysis of CHOIR." Nephrology, Dialysis, Transplantation : Official Publication of the European Dialysis and Transplant Association European Renal Association 27, no. 9 (September 2012): 3606-3614. Full Text
  - Lungren, MP, Samei, E, Barnhart, H, McAdams, HP, Leder, RA, Christensen, JD, Wylie, JD, Tan, JW, Li, X, and Hurwitz, LM. "Gray-scale inversion radiographic display for the detection of pulmonary nodules on chest radiographs." Clin Imaging 36, no. 5 (September 2012): 515-521. Full Text Link to Item
  - Ardoin, SP, Evans, G, Sandborg, C, Barnhart, HX, and Schanberg, LE. "Reply." Arthritis & Rheumatism 64, no. 8 (August 2012): 2805-2806. Full Text
  - Mazurowski, MA, Barnhart, HX, Baker, JA, and Tourassi, GD. "Identifying error-making patterns in assessment of mammographic BI-RADS descriptors among radiology residents using statistical pattern recognition." Acad Radiol 19, no. 7 (July 2012): 865-871. Full Text Link to Item
  - Ho, LM, Marin, D, Neville, AM, Barnhart, HX, Gupta, RT, Paulson, EK, and Boll, DT. "Characterization of adrenal nodules with dual-energy CT: can virtual unenhanced attenuation values replace true unenhanced attenuation values?." Ajr. American Journal of Roentgenology 198, no. 4 (April 2012): 840-845. Full Text
  - Chen, B, Barnhart, H, Richard, S, Colsher, J, Amurao, M, and Samei, E. "Quantitative CT: technique dependence of volume estimation on pulmonary nodules." Phys Med Biol 57, no. 5 (March 7, 2012): 1335-1348. Full Text Link to Item
  - Allen, BC, Barnhart, H, Bashir, M, Nieman, C, Breault, S, and Jaffe, TA. "Diagnostic accuracy of intra-abdominal fluid collection characterization in the era of multidetector computed tomography." The American Surgeon 78, no. 2 (February 2012): 185-189.
  - Chalasani, N, Vuppalanchi, R, Navarro, V, Fontana, R, Bonkovsky, H, Barnhart, H, Kleiner, DE, and Hoofnagle, JH. "Acute liver injury due to flavocoxid (Limbrel), A medical food for osteoarthritis: A case series." Annals of Internal Medicine 156, no. 12 (2012): 857-860. Full Text
  - Pan, Y, Haber, M, Gao, J, and Barnhart, HX. "A new permutation-based method for assessing agreement between two observers making replicated quantitative readings." Statistics in Medicine 31, no. 20 (2012): 2249-2261. Full Text
  - Schanberg, LE, Sandborg, C, Barnhart, HX, Ardoin, SP, Yow, E, Evans, GW, Mieszkalski, KL, Ilowite, NT, Eberhard, A, Imundo, LF, Kimura, Y, von Scheven, E, Silverman, E, Bowyer, SL, Punaro, M, Singer, NG, Sherry, DD, McCurdy, D, Klein-Gitelman, M, Wallace, C, Silver, R, Wagner-Weiner, L, Higgins, GC, Brunner, HI, Jung, L, Soep, JB, Reed, AM, Provenzale, J, Thompson, SD, and Atherosclerosis Prevention in Pediatric Lupus Erythematosus Investigators, . "Use of atorvastatin in systemic lupus erythematosus in children and adolescents." Arthritis and Rheumatism 64, no. 1 (January 2012): 285-296. Full Text
  - Marin, D, Nelson, RC, Guerrisi, A, Barnhart, H, Schindera, ST, Passariello, R, and Catalano, C. "64-section multidetector CT of the upper abdomen: optimization of a saline chaser injection protocol for improved vascular and parenchymal contrast enhancement." Eur Radiol 21, no. 9 (September 2011): 1938-1947. Full Text Link to Item
  - Patel, MR, Smalling, RW, Thiele, H, Barnhart, HX, Zhou, Y, Chandra, P, Chew, D, Cohen, M, French, J, Perera, D, and Ohman, EM. "Intra-aortic balloon counterpulsation and infarct size in patients with acute anterior myocardial infarction without shock: the CRISP AMI randomized trial." Jama 306, no. 12 (September 2011): 1329-1337. Full Text
  - Lessne, ML, Shah, P, Alexander, MJ, Barnhart, HX, Powers, CJ, Golshani, K, Ferrell, A, Enterline, D, Zomorodi, A, Smith, T, and Britz, GW. "Thromboembolic complications after Neuroform stent-assisted treatment of cerebral aneurysms: the Duke Cerebrovascular Center experience in 235 patients with 274 stents." Neurosurgery 69, no. 2 (August 2011): 369-375. Full Text Link to Item
  - Kilani, RK, Paxton, BE, Stinnett, SS, Barnhart, HX, Bindal, V, and Lungren, MP. "Self-referral in medical imaging: a meta-analysis of the literature." J Am Coll Radiol 8, no. 7 (July 2011): 469-476. Full Text Link to Item
  - Li, X, Samei, E, Barnhart, HX, Gaca, AM, Hollingsworth, CL, Maxfield, CM, Carrico, CWT, Colsher, JG, and Frush, DP. "Lung nodule detection in pediatric chest CT: quantitative relationship between image quality and radiologist performance." Med Phys 38, no. 5 (May 2011): 2609-2618. Full Text Link to Item
  - Chen, B, Samei, E, Colsher, J, Barnhart, H, Marin, D, and Nelson, R. "Precision of iodine quantification in hepatic CT: Effects of reconstruction (FBP and MBIR) and imaging parameters." Progress in Biomedical Optics and Imaging - Proceedings of SPIE 7961 (2011). Full Text
  - Chen, C-C, and Barnhart, HX. "Assessing agreement with repeated measures for random observers." Statistics in Medicine 30, no. 30 (2011): 3546-3559. Full Text
  - Guerrisi, A, Marin, D, Nelson, RC, Filippis, GD, Martino, MD, Barnhart, H, Masciangelo, R, Guerrisi, I, Passariello, R, and Catalano, C. "Effect of varying contrast material iodine concentration and injection technique on the conspicuity of hepatocellular carcinoma during 64-section MDCT of patients with cirrhosis." British Journal of Radiology 84, no. 1004 (2011): 698-708. Full Text
  - Kilani, RK, Paxton, BE, Stinnett, SS, Barnhart, HX, Bindal, V, and Lungren, MP. "Self-referral in medical imaging: A meta-analysis of the literature." Journal of the American College of Radiology 8, no. 7 (2011): 469-476. Full Text
  - Pan, Y, Haber, M, and Barnhart, HX. "A new permutation-based method for assessing agreement between two observers making replicated binary readings." Statistics in Medicine 30, no. 8 (2011): 839-853. Full Text
  - Ardoin, SP, Schanberg, LE, Sandborg, C, Yow, E, Barnhart, HX, Mieszkalski, KL, Ilowite, NT, von Scheven, E, Eberhard, A, Levy, DM, Kimura, Y, Silverman, E, Bowyer, SL, Punaro, L, Singer, NG, Sherry, DD, McCurdy, D, Klein-Gitelman, M, Wallace, C, Silver, R, Wagner-Weiner, L, Higgins, GC, Brunner, HI, Jung, LK, Imundo, L, Soep, JB, Reed, AM, and APPLE investigators, . "Laboratory markers of cardiovascular risk in pediatric SLE: the APPLE baseline cohort." Lupus 19, no. 11 (October 2010): 1315-1325. Full Text
  - Pagidas, K, Carson, SA, McGovern, PG, Barnhart, HX, Myers, ER, Legro, RS, Diamond, MP, Carr, BR, Schlaff, WD, Coutifaris, C, Steinkampf, MP, Cataldo, NA, Nestler, JE, Gosman, G, Giudice, LC, and National Institute of Child Health and Human Development-Reproductive Medicine Network, . "Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial." Fertil Steril 94, no. 4 (September 2010): 1444-1446. Full Text Link to Item
  - Pagidas, K, Carson, SA, McGovern, PG, Barnhart, HX, Myers, ER, Legro, RS, Diamond, MP, Carr, BR, Schlaff, WD, Coutifaris, C, Steinkampf, MP, Cataldo, NA, Nestler, JE, Gosman, G, Giudice, LC, and National Institute of Child Health and Human Development-Reproductive Medicine Network, . "Body mass index and intercourse compliance." Fertil Steril 94, no. 4 (September 2010): 1447-1450. Full Text Link to Item
  - Marin, D, Nelson, RC, Barnhart, H, Schindera, ST, Ho, LM, Jaffe, TA, Yoshizumi, TT, Youngblood, R, and Samei, E. "Detection of pancreatic tumors, image quality, and radiation dose during the pancreatic parenchymal phase: effect of a low-tube-voltage, high-tube-current CT technique--preliminary results." Radiology 256, no. 2 (August 2010): 450-459. Full Text
  - Gupta, RT, Ho, LM, Marin, D, Boll, DT, Barnhart, HX, and Nelson, RC. "Dual-energy CT for characterization of adrenal nodules: initial experience." AJR Am J Roentgenol 194, no. 6 (June 2010): 1479-1483. Full Text Link to Item
  - Cutler, SJ, Perez, KL, Barnhart, HX, and Tornai, MP. "Observer detection limits for a dedicated SPECT breast imaging system." Phys Med Biol 55, no. 7 (April 7, 2010): 1903-1916. Full Text Link to Item
  - Mazurowski, MA, Baker, JA, Barnhart, HX, and Tourassi, GD. "Individualized computer-aided education in mammography based on user modeling: concept and preliminary experiments." Med Phys 37, no. 3 (March 2010): 1152-1160. Full Text Link to Item
  - Gaca, AM, Barnhart, HX, and Bisset, GS. "Evaluation of wedging of lower thoracic and upper lumbar vertebral bodies in the pediatric population." AJR Am J Roentgenol 194, no. 2 (February 2010): 516-520. Full Text Link to Item
  - Marin, D, Ho, LM, Barnhart, H, Neville, AM, White, RR, and Paulson, EK. "Percutaneous abscess drainage in patients with perforated acute appendicitis: effectiveness, safety, and prediction of outcome." Ajr. American Journal of Roentgenology 194, no. 2 (February 2010): 422-429. Full Text
  - Szczech, LA, Barnhart, HX, Sapp, S, Felker, GM, Hernandez, A, Reddan, D, Califf, RM, Inrig, JK, Patel, UD, and Singh, AK. "A secondary analysis of the CHOIR trial shows that comorbid conditions differentially affect outcomes during anemia treatment." Kidney International 77, no. 3 (February 2010): 239-246. Full Text
  - Pan, Y, Gao, J, Haber, M, and Barnhart, HX. "Estimation of coefficients of individual agreement (CIAs) for quantitative and binary data using SAS and R." Computer Methods and Programs in Biomedicine 98, no. 2 (2010): 214-219. Full Text
  - Rausch, ME, Legro, RS, Barnhart, HX, Schlaff, WD, Carr, BR, Diamond, MP, Carson, SA, Steinkampf, MP, McGovern, PG, Cataldo, NA, Gosman, GG, Nestler, JE, Giudice, LC, Leppert, PC, Myers, ER, and Coutifaris, C. "Predictors of Pregnancy in Women With Polycystic Ovary Syndrome." Obstetrical & Gynecological Survey 65, no. 1 (January 2010): 30-32. Full Text
  - Barnhart, HX, and Barboriak, DP. "Applications of the repeatability of quantitative imaging biomarkers: a review of statistical analysis of repeat data sets." Translational Oncology 2, no. 4 (December 2009): 231-235. Full Text
  - Rausch, ME, Legro, RS, Barnhart, HX, Schlaff, WD, Carr, BR, Diamond, MP, Carson, SA, Steinkampf, MP, McGovern, PG, Cataldo, NA, Gosman, GG, Nestler, JE, Giudice, LC, Leppert, PC, Myers, ER, Coutifaris, C, and Reproductive Medicine Network, . "Predictors of pregnancy in women with polycystic ovary syndrome." J Clin Endocrinol Metab 94, no. 9 (September 2009): 3458-3466. Full Text Link to Item
  - Schanberg, LE, Sandborg, C, Barnhart, HX, Ardoin, SP, Yow, E, Evans, GW, Mieszkalski, KL, Ilowite, NT, Eberhard, A, Levy, DM, Kimura, Y, von Scheven, E, Silverman, E, Bowyer, SL, Punaro, L, Singer, NG, Sherry, DD, McCurdy, D, Klein-Gitelman, M, Wallace, C, Silver, R, Wagner-Weiner, L, Higgins, GC, Brunner, HI, Jung, L, Soep, JB, Reed, A, and Atherosclerosis Prevention in Pediatric Lupus Erythematosus Investigators, . "Premature atherosclerosis in pediatric systemic lupus erythematosus: risk factors for increased carotid intima-media thickness in the atherosclerosis prevention in pediatric lupus erythematosus cohort." Arthritis and Rheumatism 60, no. 5 (May 2009): 1496-1507. Full Text
  - Chen, CC, and Barnhart, HX. "Comparison of ICC and CCC for assessing agreement for data without and with replications." Computational Statistics and Data Analysis 53, no. 2 (December 15, 2008): 554-564. Full Text
  - May, C, and Barnhart, HX. "Use of concordance correlation coefficient in objective and subjective assessment of limb function." Vet Surg 37, no. 7 (October 2008): 706-707. (Letter) Full Text Link to Item
  - McGovern, PG, Carson, SA, Barnhart, HX, Myers, ER, Legro, RS, Diamond, MP, Carr, BR, Schlaff, WD, Coutifaris, C, Cataldo, NA, Steinkampf, MP, Nestler, JE, Gosman, G, Leppert, PC, Giudice, LC, and National Institute of Child Health and Human Development-Reproductive Medicine Network, . "Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial." Fertility and Sterility 90, no. 4 (October 2008): 1283-1286. Full Text
  - Szczech, LA, Barnhart, HX, Inrig, JK, Reddan, DN, Sapp, S, Califf, RM, Patel, UD, and Singh, AK. "Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes." Kidney International 74, no. 6 (September 2008): 791-798. Full Text
  - Cataldo, NA, Barnhart, HX, Legro, RS, Myers, ER, Schlaff, WD, Carr, BR, Diamond, MP, Carson, SA, Steinkampf, MP, Coutifaris, C, McGovern, PG, Gosman, G, Nestler, JE, Giudice, LC, and Reproductive Medicine Network, . "Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome." The Journal of Clinical Endocrinology and Metabolism 93, no. 8 (August 2008): 3124-3127. Full Text
  - Haber, M, and Barnhart, HX. "A general approach to evaluating agreement between two observers or methods of measurement from quantitative data with replicated measurements." Stat Methods Med Res 17, no. 2 (April 2008): 151-169. Full Text Link to Item
  - Trimble, MA, Velazquez, EJ, Adams, GL, Honeycutt, EF, Pagnanelli, RA, Barnhart, HX, Chen, J, Iskandrian, AE, Garcia, EV, and Borges-Neto, S. "Repeatability and reproducibility of phase analysis of gated single-photon emission computed tomography myocardial perfusion imaging used to quantify cardiac dyssynchrony." Nuclear Medicine Communications 29, no. 4 (April 2008): 374-381. Full Text
  - Legro, RS, Barnhart, HX, Schlaff, WD, Carr, BR, Diamond, MP, Carson, SA, Steinkampf, MP, Coutifaris, C, McGovern, PG, Cataldo, NA, Gosman, GG, Nestler, JE, Giudice, LC, Ewens, KG, Spielman, RS, Leppert, PC, Myers, ER, and Reproductive Medicine Network, . "Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene." The Journal of Clinical Endocrinology and Metabolism 93, no. 3 (March 2008): 792-800. Full Text
  - Jung, S-H, Barnhart, HX, Sohn, I, Stinnett, SS, and Wallace, DK. "Sample size for comparing correlated concordance rates." J Biopharm Stat 18, no. 2 (2008): 359-369. Full Text Link to Item
  - Crawford, SB, Kosinski, AS, Lin, H-M, Williamson, JM, and Barnhart, HX. "Computer programs for the concordance correlation coefficient." Comput Methods Programs Biomed 88, no. 1 (October 2007): 62-74. Full Text Link to Item
  - Barnhart, HX. "Guest editor's note for the special issue on assessing agreement." Journal of Biopharmaceutical Statistics 17, no. 4 (July 1, 2007): 525-527. Full Text
  - Legro, RS, Barnhart, HX, Schlaff, WD, Carr, BR, Diamond, MP, Carson, SA, Steinkampf, MP, Coutifaris, C, McGovern, PG, Cataldo, NA, Gosman, GG, Nestler, JE, Giudice, LC, Leppert, PC, Myers, ER, and Cooperative Multicenter Reproductive Medicine Network, . "Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome." The New England Journal of Medicine 356, no. 6 (February 2007): 551-566. Full Text
  - McGovern, PG, Legro, RS, Myers, ER, Barnhart, HX, Carson, SA, Diamond, MP, Carr, BR, Schlaff, WD, Coutifaris, C, Steinkampf, MP, Nestler, JE, Gosman, G, Leppert, PC, Giudice, LC, and National Institutes for Child Health and Human Development-Reproductive Medicine Network, . "Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome." Fertil Steril 87, no. 2 (February 2007): 442-444. Full Text Link to Item
  - Barnhart, HX, Haber, MJ, and Lin, LI. "An overview on assessing agreement with continuous measurements." Journal of Biopharmaceutical Statistics 17, no. 4 (January 2007): 529-569. (Review) Full Text
  - Barnhart, HX, Kosinski, AS, and Haber, MJ. "Assessing individual agreement." J Biopharm Stat 17, no. 4 (2007): 697-719. Full Text Link to Item
  - Barnhart, HX, Lokhnygina, Y, Kosinski, AS, and Haber, M. "Comparison of concordance correlation coefficient and coefficient of individual agreement in assessing agreement." J Biopharm Stat 17, no. 4 (2007): 721-738. Full Text Link to Item
  - Haber, M, Gao, J, and Barnhart, HX. "Assessing observer agreement in studies involving replicated binary observations." J Biopharm Stat 17, no. 4 (2007): 757-766. Full Text Link to Item
  - Singh, AK, Szczech, L, Tang, KL, Barnhart, H, Sapp, S, Wolfson, M, and Reddan, D. "Anaemia of CKD - The CHOIR study revisited." Nephrology Dialysis Transplantation 22, no. 7 (2007): 1806-1810. Full Text
  - Singh, AK, Szczech, L, Tang, KL, Barnhart, H, Sapp, S, Wolfson, M, Reddan, D, and CHOIR Investigators, . "Correction of anemia with epoetin alfa in chronic kidney disease." The New England Journal of Medicine 355, no. 20 (November 2006): 2085-2098. Full Text
  - Legro, RS, Myers, ER, Barnhart, HX, Carson, SA, Diamond, MP, Carr, BR, Schlaff, WD, Coutifaris, C, McGovern, PG, Cataldo, NA, Steinkampf, MP, Nestler, JE, Gosman, G, Guidice, LC, Leppert, PC, and Reproductive Medicine Network, . "The Pregnancy in Polycystic Ovary Syndrome study: baseline characteristics of the randomized cohort including racial effects." Fertility and Sterility 86, no. 4 (October 2006): 914-933. Full Text
  - Lin, CY, Barnhart, HX, and Kosinski, AS. "The weighted generalized estimating equations approach for the evaluation of medical diagnostic test at subunit level." Biom J 48, no. 5 (August 2006): 758-771. Link to Item
  - Haber, M, and Barnhart, HX. "Coefficients of agreement for fixed observers." Stat Methods Med Res 15, no. 3 (June 2006): 255-271. Full Text Link to Item
  - Kuklina, EV, Ramakrishnan, U, Stein, AD, Barnhart, HH, and Martorell, R. "Early childhood growth and development in rural Guatemala." Early Human Development 82, no. 7 (2006): 425-433. Full Text
  - Barnhart, HX, Song, J, and Lyles, RH. "Assay validation for left-censored data." Stat Med 24, no. 21 (November 15, 2005): 3347-3360. Full Text Link to Item
  - Webb, AL, Conlisk, AJ, Barnhart, HX, Martorell, R, Grajeda, R, and Stein, AD. "Maternal and childhood nutrition and later blood pressure levels in young Guatemalan adults." Int J Epidemiol 34, no. 4 (August 2005): 898-904. Full Text Link to Item
  - Barnhart, HX, Song, J, and Haber, MJ. "Assessing intra, inter and total agreement with replicated readings." Stat Med 24, no. 9 (May 15, 2005): 1371-1384. Full Text Link to Item
  - Kutner, NG, Zhang, R, Barnhart, H, and Collins, AJ. "Health status and quality of life reported by incident patients after 1 year on haemodialysis or peritoneal dialysis." Nephrology Dialysis Transplantation 20, no. 10 (2005): 2159-2167. Full Text
  - Conlisk, AJ, Barnhart, HX, Martorell, R, Grajeda, R, and Stein, AD. "Maternal and child nutritional supplementation are inversely associated with fasting plasma glucose concentration in young Guatemalan adults." J Nutr 134, no. 4 (April 2004): 890-897. Link to Item
  - Stein, AD, Barnhart, HX, Wang, M, Hoshen, MB, Ologoudou, K, Ramakrishnan, U, Grajeda, R, Ramirez-Zea, M, and Martorell, R. "Comparison of linear growth patterns in the first three years of life across two generations in Guatemala." Pediatrics 113, no. 3 Pt 1 (March 2004): e270-e275. Link to Item
  - Kuklina, EV, Ramakrishnan, U, Stein, AD, Barnhart, HH, and Martorell, R. "Growth and diet quality are associated with the attainment of walking in rural Guatemalan infants." Journal of Nutrition 134, no. 12 (2004): 3296-3300.
  - Li, H, DiGirolamo, AM, Barnhart, HX, Stein, AD, and Martorell, R. "Relative importance of birth size and postnatal growth for women's educational achievement." Early Hum Dev 76, no. 1 (January 2004): 1-16. Link to Item
  - Stein, AD, Barnhart, HX, Wang, M, Hoshen, MB, Ologoudou, K, Ramakrishnan, U, Grajeda, R, Ramirez-Zea, M, and Martorell, R. "Comparison of linear growth patterns in the first three years of life across two generations in Guatemala." Pediatrics 113, no. 3 Pt 1 (January 1, 2004).
  - Wolf, SL, Barnhart, HX, Kutner, NG, McNeely, E, Coogler, C, Xu, T, and Atlanta FICSIT Group, . "Selected as the best paper in the 1990s: Reducing frailty and falls in older persons: an investigation of tai chi and computerized balance training." Journal of the American Geriatrics Society 51, no. 12 (December 2003): 1794-1803. Full Text
  - Li, H, Barnhart, HX, Stein, AD, and Martorell, R. "Effects of early childhood supplementation on the educational achievement of women." Pediatrics 112, no. 5 (November 2003): 1156-1162. Link to Item
  - Kosinski, AS, and Barnhart, HX. "A global sensitivity analysis of performance of a medical diagnostic test when verification bias is present." Stat Med 22, no. 17 (September 15, 2003): 2711-2721. Full Text Link to Item
  - Barnhart, HX, and Kosinski, AS. "Evaluating medical diagnostic tests at the subunit level in the presence of verification bias." Stat Med 22, no. 13 (July 15, 2003): 2161-2176. Full Text Link to Item
  - Berkowitz, Z, Barnhart, HX, and Kaye, WE. "Factors associated with severity of injury resulting from acute releases of hazardous substances in the manufacturing industry." Journal of Occupational and Environmental Medicine 45, no. 7 (July 2003): 734-742. Full Text
  - Dana Flanders, W, Barnhart, HX, and Kosinski, AS. "An estimated score method for missing and auxiliary covariates in two stage studies." Journal of Statistical Planning and Inference 115, no. 1 (July 2003): 145-170. Full Text
  - Stein, AD, Barnhart, HX, Hickey, M, Ramakrishnan, U, Schroeder, DG, and Martorell, R. "Prospective study of protein-energy supplementation early in life and of growth in the subsequent generation in Guatemala." Am J Clin Nutr 78, no. 1 (July 2003): 162-167. Link to Item
  - Li, H, Stein, AD, Barnhart, HX, Ramakrishnan, U, and Martorell, R. "Associations between prenatal and postnatal growth and adult body size and composition." Am J Clin Nutr 77, no. 6 (June 2003): 1498-1505. Link to Item
  - Kosinski, AS, and Barnhart, HX. "Accounting for nonignorable verification bias in assessment of diagnostic tests." Biometrics 59, no. 1 (March 2003): 163-171. Link to Item
  - Zhao, X-Q, Kosinski, AS, Barnhart, HX, Superko, HR, and King, SB. "Prediction of native coronary artery disease progression following PTCA or CABG in the Emory Angioplasty Versus Surgery Trial." Med Sci Monit 9, no. 2 (February 2003): CR48-CR54. Link to Item
  - Vitek, JL, Bakay, RAE, Freeman, A, Evatt, M, Green, J, McDonald, W, Haber, M, Barnhart, H, Wahlay, N, Triche, S, Mewes, K, Chockkan, V, Zhang, J-Y, and DeLong, MR. "Randomized trial of pallidotomy versus medical therapy for Parkinson's disease." Annals of Neurology 53, no. 5 (2003): 558-569. Full Text
  - Allen, AS, and Barnhart, HX. "Joint models for toxicology studies with dose-dependent number of implantations." Risk Anal 22, no. 6 (December 2002): 1165-1173. Link to Item
  - Barnhart, HX, Haber, M, and Song, J. "Overall concordance correlation coefficient for evaluating agreement among multiple observers." Biometrics 58, no. 4 (December 2002): 1020-1027. Link to Item
  - Barnhart, HX, and Williamson, JM. "Weighted least-squares approach for comparing correlated kappa." Biometrics 58, no. 4 (December 2002): 1012-1019. Link to Item
  - Green, J, McDonald, WM, Vitek, JL, Haber, M, Barnhart, H, Bakay, RAE, Evatt, M, Freeman, A, Wahlay, N, Triche, S, Sirockman, B, and DeLong, MR. "Neuropsychological and psychiatric sequelae of pallidotomy for PD: Clinical trial findings." Neurology 58, no. 6 (2002): 858-865.
  - Barnhart, HX, and Williamson, JM. "Modeling concordance correlation via GEE to evaluate reproducibility." Biometrics 57, no. 3 (September 2001): 931-940. Full Text
  - Green, J, and Barnhart, H. "The impact of lesion laterality on neuropsychological change following posterior pallidotomy: A review of current findings." Brain and Cognition 42, no. 3 (2000): 379-398. Full Text
  - Kutner, NG, Mistretta, EF, Barnhart, HX, and Belodoff, BF. "Family Members' Perceptions of Quality of Life Change in Dementia SCU Residents." Journal of Applied Gerontology 18, no. 4 (December 1999): 423-439. Full Text
  - Stiger, TR, Barnhart, HX, and Williamson, JM. "Testing proportionality in the proportional odds model fitted with GEE." Statistics in Medicine 18, no. 11 (June 15, 1999): 1419-1433. Full Text
  - Stiger, TR, Barnhart, HX, and Williamson, JM. "Testing proportionality in the proportional odds model fitted with GEE." Stat Med 18, no. 11 (June 15, 1999): 1419-1433. Link to Item
  - Barnhart, HX, Kosinski, AS, and Sampson, AR. "A regression model for multivariate random length data." Statistics in Medicine 18, no. 2 (January 1999): 199-211. Full Text
  - Ramakrishnan, U, Barnhart, H, Schroeder, DG, Stein, AD, and Martorell, R. "Early childhood nutrition, education and fertility milestones in Guatemala." Journal of Nutrition 129, no. 12 (1999): 2196-2202.
  - Zhao, XQ, Kosinski, AS, Malinow, R, Barnhart, HX, Davis, JW, Brown, BG, and King, SB. "Association of plasma homocyst(e)ine levels and atherogenic risk factors with native coronary new lesion formation and graft disease after PTCA or CABG in EAST." CIRCULATION 98, no. 17 (October 27, 1998): 439-439. Link to Item
  - Barnhart, HX, and Williamson, JM. "Goodness-of-fit tests for GEE modeling with binary responses." Biometrics 54, no. 2 (June 1998): 720-729. Full Text
  - Zhao, X. "Effect of Plasma Homocyst(e)ine Levels on Adverse Cardiovascular Outcomes After PTCA or CABG in EAST." Journal of the American College of Cardiology 31, no. 2 (February 1998): 89A-89A. Full Text
  - Barnhart, HX. "A probit model for multivariate random length ordinal data." Communications in Statistics - Theory and Methods 27, no. 7 (1998): 1693-1713.
  - Stiger, TR, Kosinski, AS, Barnhart, HX, and Kleinbaum, DG. "ANOVA for repeated ordinal data with small sample size? A comparison of ANOVA, MANOVA, WLS and GEE methods by simulation." Communications in Statistics Part B: Simulation and Computation 27, no. 2 (January 1, 1998): 357-375. Full Text
  - Albert, PS, Follmann, DA, and Barnhart, HX. "A generalized estimating equation approach for modeling random length binary vector data." Biometrics 53, no. 3 (September 1997): 1116-1124. Link to Item
  - King, SB, Barnhart, HX, Kosinski, AS, Weintraub, WS, Lembo, NJ, Petersen, JY, Douglas, JS, Jones, EL, Craver, JM, Guyton, RA, Morris, DC, and Liberman, HA. "Angioplasty or surgery for multivessel coronary artery disease: comparison of eligible registry and randomized patients in the EAST trial and influence of treatment selection on outcomes. Emory Angioplasty versus Surgery Trial Investigators." Am J Cardiol 79, no. 11 (June 1, 1997): 1453-1459. Link to Item
  - King, SB, Barnhart, HX, Kosinski, AS, Weintraub, WS, Lembo, NJ, Petersen, JY, Douglas, JS, Jones, EL, Craver, JM, Guyton, RA, Morris, DC, and Liberman, HA. "Angioplasty or surgery for multivessel coronary artery disease: Comparison of eligible registry and randomized patients in the EAST trial and influence of treatment selection on outcomes." American Journal of Cardiology 79, no. 11 (June 1, 1997): 1453-1459. Full Text
  - Wolf, SL, Barnhart, HX, Ellison, GL, and Coogler, CE. "The effect of Tai Chi Quan and computerized balance training on postural stability in older subjects." Physical Therapy 77, no. 4 (May 6, 1997): 371-384.
  - Wolf, SL, Barnhart, HX, Ellison, GL, and Coogler, CE. "The effect of Tai Chi Quan and computerized balance training on postural stability in older subjects. Atlanta FICSIT Group. Frailty and Injuries: Cooperative Studies on Intervention Techniques." Phys Ther 77, no. 4 (April 1997): 371-381. Link to Item
  - Kutner, NG, Barnhart, H, Wolf, SL, McNeely, E, and Xu, T. "Self-report benefits of Tai Chi practice by older adults." Journals of Gerontology - Series B Psychological Sciences and Social Sciences 52, no. 5 (1997): P242-P246.
  - Zhao, XQ, Brown, BG, Stewart, DK, Hillger, LA, Barnhart, HX, Kosinski, AS, Weintraub, WS, and King, SB. "Effectiveness of revascularization in the Emory angioplasty versus surgery trial. A randomized comparison of coronary angioplasty with bypass surgery." Circulation 93, no. 11 (June 1, 1996): 1954-1962. Link to Item
  - Barnhart, HX, Caldwell, MB, Thomas, P, Mascola, L, Ortiz, I, Hsu, HW, Schulte, J, Parrott, R, Maldonado, Y, and Byers, R. "Natural history of human immunodeficiency virus disease in perinatally infected children: an analysis from the Pediatric Spectrum of Disease Project." Pediatrics 97, no. 5 (May 1996): 710-716.
  - Wolf, SL, Barnhart, HX, Kutner, NG, McNeely, E, Coogler, C, and Xu, T. "Reducing frailty and falls in older persons: an investigation of Tai Chi and computerized balance training. Atlanta FICSIT Group. Frailty and Injuries: Cooperative Studies of Intervention Techniques." J Am Geriatr Soc 44, no. 5 (May 1996): 489-497. Link to Item
  - Wolf, SL, Barnhart, HX, Kutner, NG, McNeely, E, Coogler, C, and Xu, T. "Reducing frailty and falls in older persons: An investigation of Tai Chi and computerized balance training." Journal of the American Geriatrics Society 44, no. 5 (January 1, 1996): 489-497. Full Text
  - KOSINSKI, AS, BARNHART, HX, WEINTRAUB, WS, GUYTON, RA, and KING, SP. "5-YEAR OUTCOME AFTER CORONARY SURGERY OR CORONARY ANGIOPLASTY - RESULTS FROM THE EMORY ANGIOPLASTY VS SURGERY TRIAL (EAST)." CIRCULATION 92, no. 8 (October 15, 1995): 2594-2594. Link to Item
  - King, SB, Lembo, NJ, Weintraub, WS, Kosinski, AS, Barnhart, HX, and Kutner, MH. "Emory Angioplasty Versus Surgery Trial (EAST): design, recruitment, and baseline description of patients." Am J Cardiol 75, no. 9 (March 23, 1995): 42C-59C. Link to Item
  - Barnhart, HX, and Sampson, AR. "Multiple population models for multivariate random length data--with applications in clinical trials." Biometrics 51, no. 1 (March 1995): 195-204. Link to Item
  - King, SB, Lembo, NJ, Weintraub, WS, Kosinski, AS, Barnhart, HX, Kutner, MH, Alazraki, NP, Guyton, RA, and Zhao, XQ. "A randomized trial comparing coronary angioplasty with coronary bypass surgery. Emory Angioplasty versus Surgery Trial (EAST)." The New England Journal of Medicine 331, no. 16 (October 1994): 1044-1050. Full Text
  - Barnhart, HX, and Sampson, AR. "Overview of multinomial models for ordinal data." Communications in Statistics - Theory and Methods 23, no. 12 (January 1994): 3395-3416. Full Text
  - Barnhart, HX. "Models for Multivariate Random Length Data with Applications in Clinical Trials." Drug Information Journal 27, no. 4 (October 1993): 1147-1157. Full Text
  - Barnhart, HX. "Models for multivariate random length data with applications in clinical trials." Drug Information Journal 27, no. 4 (January 1, 1993): 1147-1157. (Review)
- Conference Papers
  - Crowley, AL, Yow, E, Rabineau, D, Norris, C, White, J, Daubert, MA, Velazquez, EJ, Barnhart, H, Krucoff, MW, Rao, SV, and Douglas, PS. "The Impact of a Rigorous Quality Program on 3D Echocardiography Data Quality in an International Multisite Randomized Trial." August 6, 2018. Full Text
  - Ahmad, J, Reddy, KR, Tillmann, HL, Chalasani, NP, Hayashi, PH, Fontana, RJ, Navarro, VJ, Stolz, A, Barnhart, HX, Cloherty, GA, and Hoofnagle, JH. "Testing for Hepatitis C Virus RNA is Recommended in Patients with Suspected Drug Induced Liver Injury (DILI)." October 2017. Link to Item
  - DiPaola, F, Molleston, J, Barnhart, HX, Chalasani, NP, Gu, S, Kleiner, DE, Hoofnagle, JH, Fontana, RJ, and Grp, DILINS. "Minocycline and anti-epileptics are the leading causes of DILI in Children." October 2017. Link to Item
  - Urban, TJ, Nicoletti, P, Chalasani, N, Serrano, J, Stolz, A, Daly, AK, Aithal, GP, Dillon, J, Navarro, V, Odin, J, Barnhart, H, Ostrov, D, Long, N, Cirulli, ET, Watkins, PB, Fontana, RJ, Drug-Induced Liver Injury Network (DILIN), , Pharmacogenetics of Drug-Induced Liver Injury group (DILIGEN), , and International Serious Adverse Events Consortium (iSAEC), . "Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B∗35:02 as a risk factor." July 2017. Full Text
  - Ahmad, J, Rossi, S, Rodgers, SK, Fontana, RJ, Chalasani, NP, Stolz, A, Hayashi, PH, Barnhart, HX, Kleiner, DE, and Bjornsson, E. "Drug Induced Liver Injury Associated with Sclerosing Cholangitis Like Changes on Magnetic Resonance Cholangiography Imaging." October 2016. Link to Item
  - Chalasani, NP, Ghabril, M, Fontana, RJ, Barnhart, HX, Hayashi, PH, Ahmad, J, Stolz, A, Navarro, VJ, and Hoofnagle, JH. "Idiosyncratic drug induced liver injury in African Americans: Causes, Clinical Features and Outcomes." October 2016. Link to Item
  - Tillmann, HL, Barnhart, HX, Serrano, J, and Rockey, DC. "A Novel Computerized Drug Induced Liver Injury Causality Assessment Tool (DILI-CAT)." October 2016. Link to Item
  - Aithal, GP, Nicoletti, P, Bjornsson, E, Lucena, MI, Andrade, RJ, Grove, J, Stephens, C, Hallberg, P, Maitland-van der Zee, AH, Martin, JH, Cascorbi, I, Dillon, JF, Laitinen, T, Larrey, DG, Molokhia, M, Kullak-Ublick, GA, Ibanez, L, Pirmohamed, M, Qin, S, Sawle, A, Bessone, F, Hernandez, N, Stolz, A, Chalasani, NP, Serrano, J, Barnhart, HX, Fontana, RJ, Watkins, P, Urban, TJ, and Daly, AK. "HLA-A*33:01 is strongly associated with drug-induced liver injury (DILI) due to terbinafine and several other unrelated compounds." October 2015. Link to Item
  - Hayashi, PH, Rockey, DC, Fontana, RJ, Tillmann, HL, Kaplowitz, N, Barnhart, HX, Gu, J, Sherker, AH, Chalasani, NP, Navarro, VJ, Ahmad, J, and Hoofnagle, JH. "Death and Liver Transplantations Occurring Within Two Years of Drug-Induced Liver Injury." October 2015. Link to Item
  - Navarro, VJ, Verma, M, Barnhart, HX, Ghabril, M, Fontana, RJ, Odin, JA, Stolz, A, Vega, M, and Watkins, PB. "The Epidemiology of Suspected Drug Induced Liver Injury in the US: The Delaware Liver Injury Study." October 2015. Link to Item
  - Stolz, A, Navarro, VJ, Hayashi, PH, Chalasani, NP, Fontana, RJ, Bonkovsky, HL, Hwang, S, Hoofnagle, JH, Kleiner, DE, and Barnhart, HX. "Severe and prolonged jaundice associated with body building supplements (BBS): review of 44 cases from the Drug-Induced Liver Injury Network (DILIN)." October 2015. Link to Item
  - Urban, TJ, Nicoletti, P, Fontana, RJ, Stolz, A, Daly, AK, Aithal, GP, Lucena, MI, Barnhart, HX, Watkins, P, and Chalasani, NP. "Genome-wide investigation identifies common SNPs on Chr9p22.2 as risk factors for liver injury due to sulfa-methoxazole/trimethoprim." October 2015. Link to Item
  - Khouri, MG, Ky, B, Dunn, G, Plappert, T, Englefield, V, Yow, E, Barnhart, HX, Sutton, MSJ, and Douglas, P. "ECHOCARDIOGRAPHY CORE LAB REPRODUCIBILITY OF CARDIAC SAFETY ASSESSMENTS IN CARDIO-ONCOLOGY." March 2015. Full Text
  - Rockey, DC. "To transfuse or not to transfuse in upper gastrointestinal hemorrhage? That is the question." July 2014. Full Text
  - Fontana, RJ, Hayashi, PH, Reddy, R, Kleiner, DE, Phillips, T, Barnhart, HX, Talwalkar, JA, Chalasani, NP, Lee, WM, Stolz, A, Davern, TJ, Watkins, PB, and Serrano, J. "Cholestatic Drug reactions are more likely to cause persistent liver injury and impaired Quality of Life during prolonged follow-up: Results from the DILIN Prospective study." 2014. Link to Item
  - Navarro, VJ, Barnhart, HX, Bonkovsky, HL, Davern, TJ, Fontana, RJ, Grant, L, Hoofnagle, JH, Reddy, KR, Seeff, LB, Serrano, J, Sherker, AH, Stolz, A, Talwalkar, JA, Vega, M, and Vuppalanchi, R. "The Rising Burden of Herbal and Dietary Supplement Induced Hepatotoxicity in the U. S. A." October 2013. Link to Item
  - Fontana, RJ, Gu, J, Barnhart, HX, Hayashi, PH, Reddy, KR, Talwalkar, J, Chalasani, NP, Lee, WM, Stolz, A, Davern, TJ, Watkins, P, and Serrano, J. "Subject race and liver biochemical profile are strongly associated with clinical outcomes and chronic liver injury: Results from the DILIN Prospective study." October 2012. Link to Item
  - Foureau, DM, Walling, TL, Kleiner, DE, Ahrens, WA, Jacobs, WC, McKillop, LH, Barnhart, HX, Serrano, J, and Bonkovsky, HL. "Profiles of Leukocytes Infiltrating Livers of Subjects with Drug-Induced Liver Injury (DILI)." October 2012. Link to Item
  - Hayashi, PH, Barnhart, HX, Fontana, RJ, Chalasani, NP, Davern, TJ, Talwalkar, J, Reddy, KR, Stolz, A, Hoofnagle, JH, and Rockey, DC. "Reliability of the Drug Induced Liver Injury Network (DILIN) Expert Opinion Process in the Diagnosis of DILI." October 2012. Link to Item
  - Urban, TJ, Shianna, K, Barnhart, HX, Chalasani, NP, Fontana, RJ, Serrano, J, Stolz, A, Goldstein, DB, and Watkins, PB. "Whole-exome sequencing identifies rare genetic variants that may contribute to isoniazid (INH)-induced liver injury." October 2012. Link to Item
  - Navarro, VJ, Barnhart, HX, Bonkovsky, HL, Reddy, KR, Seeff, L, Serrano, J, Talwalkar, JA, Vega, M, Vuppalanchi, R, and Investigators, DILIN. "DIAGNOSING HEPATOTOXICITY ATTRIBUTABLE TO HERBAL & DIETARY SUPPLEMENTS (HDS): TEST-RETEST RELIABILITY OF A NOVEL CAUSALITY ASSESSMENT TOOL." April 2012. Full Text Link to Item
  - Navarro, VJ, Barnhart, HX, Bonkovsky, HL, and Hwang, S-I. "GREEN TEA EXTRACT CONTAINING HERBAL & DIETARY SUPPLEMENTS ARE FREQUENTLY MISLABELED IN THE USA: THE US DRUG-INDUCED LIVER INJURY NETWORK (DILIN) EXPERIENCE." October 2011. Link to Item
  - Chen, B, Richard, S, Barnhart, H, Colsher, J, Amurao, M, and Samei, E. "Quantitative CT: Technique dependency of volume assessment for pulmonary nodules." December 1, 2010. Full Text
  - Cataldo, NA, Legro, RS, Myers, ER, and Barnhart, HX. "Co-treatment with metformin XR does not reduce the threshold dose of clomiphene to induce ovulation in polycystic ovary syndrome: results from the pregnancy in polycystic ovary syndrome (PPCOS) study." : Elsevier BV, September 2007. Full Text
  - Legro, RS, Myers, ER, Barnhart, HX, Carson, SA, Diamond, MP, Carr, BA, Schlaff, WD, Coutifaris, C, McGovern, PG, Cataldo, NA, Steinkampf, MP, Nestler, JE, Gosman, G, Giudice, LC, and Leppert, PC. "Pregnancy in polycystic ovary syndrome (PPCOS) baseline characteristics: Effect of race and ethnicity on the PCOS phenotype." February 2006. Link to Item
  - Legro, RS, Myers, ER, Barnhart, HX, Carson, SA, Diamond, MP, Carr, BA, Schlaff, WD, Coutifaris, C, McGovern, PG, Cataldo, NA, Steinkampf, MP, Nestler, JE, Gosman, G, Giudice, LC, and Leppert, PC. "Pregnancy in polycystic ovary syndrome (PPCOS): Study design and baseline characteristics of the randomized cohort." February 2006. Link to Item
  - Kosinski, AS, Barnhart, HX, and Weintraub, WS. ""Ignorance region" of sensitivity and specificity of a diagnostic test when not all patients are verified with a gold standard." November 2002. Link to Item
Teaching & Mentoring
Recent Courses
- BIOSTAT 720: Master's Project 2019
- BIOSTAT 740: Continuation 2019
- BIOSTAT 900: Current Problems in Biostatistics 2019
- BIOSTAT 908: Independent Study (Rotations) 2019
- BIOSTAT 909: Internship Course 2019
- BIOSTAT 714: Categorical Data Analysis 2018

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