Huiman Xie Barnhart | Scholars@Duke

Huiman Xie Barnhart
Professor of Biostatistics and Bioinformatics

My research interests include both statistical methodology and disease-specific clinical research biostatistics. My statistical research areas include methods for assessing reliability/agreement between methods or raters, evaluating performance of new medical diagnostic tests, missing data, correlated categorical data and methods for clinical trials. My collaborative research include the following clinical areas: cardiovascular imaging, radiology imaging, cardiovascular disease, renal disease, reproductive medicine, Parkinson disease, and aging.

Current Appointments & Affiliations

Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2009
Member in the Duke Clinical Research Institute, Duke Clinical Research Institute, Institutes and Centers 2003

Contact Information

7th Floor North Pavilion, Durham, NC 27710
Duke Box 3850, Durham, NC 27710
huiman.barnhart@duke.edu (919) 668-8403

Background
Education, Training, & Certifications
- Associate Professor (with Tenure), Biostatistics, Emory University 1998 - 2003
- Assistant Professor (Tenure Track), Biostatistics, Emory University 1992 - 1998
- Grad Student Researcher, Epid. Data Coord. Ctr., Epidemiology, University of Pittsburgh 1989 - 1992
- Ph.D., University of Pittsburgh 1992
- Teaching Assistant, Mathematics And Statistics, University of Pittsburgh 1986 - 1989
- M.A., University of Pittsburgh 1988
Duke Appointment History
- Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2006 - 2009
- Associate Professor of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2004 - 2006
- Instructor, Temporary of Biostatistics and Bioinformatics, Biostatistics & Bioinformatics, Basic Science Departments 2003 - 2004
Research
Selected Grants
- Coordinating Center for the Drug Induced Liver Injury Network (DILIN) awarded by National Institutes of Health 2003 - 2023
- Coordinating Center for the Drug Induced Liver Injury Network (DILIN)- Supplement awarded by National Institute of Diabetes and Digestive and Kidney Diseases 2003 - 2023
- 2/2 A comparison of individualized vs. weight based protocols to treat vaso-occlusive episodes in Sickle Cell Disease (COMPARE VOE) awarded by National Institutes of Health 2018 - 2022
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2020
- PACTTE-Partnership for Anemia: Clinical and Translational Trials in the Elderly awarded by National Institutes of Health 2009 - 2020
- Integrated Biostatistical Training for CVD Research awarded by North Carolina State University 2017 - 2019
- AASLD Innovation Fund awarded by University of North Carolina - Chapel Hill 2017 - 2019
- Coordinating Center for the Drug Induced Liver Injury Network (DILIN) awarded by National Institutes of Health 2008 - 2018
- Simultaneous Emission and Transmission Mammotomography awarded by National Institutes of Health 2002 - 2014
- Analysis of associations between anemia correction in CKD and mortality: CHOIR awarded by National Institutes of Health 2008 - 2012
- Nitric Oxide Metabolism in Statin-treated Pediatric SLE awarded by National Institutes of Health 2003 - 2011
- Blood pressure, endothelial cell dysfunction and outcomes in kidney disease awarded by National Institutes of Health 2008
- Cooperative Multi-Center Reproductive Medicine Network awarded by National Institutes of Health 2000 - 2008
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Stolz, Andrew, Victor Navarro, Paul H. Hayashi, Robert J. Fontana, Huiman X. Barnhart, Jiezhun Gu, Naga P. Chalasani, et al. “Severe and protracted cholestasis in 44 young men taking bodybuilding supplements: assessment of genetic, clinical and chemical risk factors..” Alimentary Pharmacology & Therapeutics 49, no. 9 (May 2019): 1195–1204. https://doi.org/10.1111/apt.15211.
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  - Ahmad, Jawad, K Rajender Reddy, Hans L. Tillmann, Paul H. Hayashi, Naga Chalasani, Robert J. Fontana, Victor J. Navarro, et al. “Importance of Hepatitis C Virus RNA Testing in Patients with Suspected Drug-Induced Liver Injury..” Dig Dis Sci, March 29, 2019. https://doi.org/10.1007/s10620-019-05591-w.
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  - Ambrosy, Andrew P., Jerry H. Gurwitz, Grace H. Tabada, Andrew Artz, Stanley Schrier, Sunil V. Rao, Huiman X. Barnhart, et al. “Incident Anemia in Older Adults with Heart Failure Rate, Etiology, and Association with Outcomes..” European Heart Journal. Quality of Care & Clinical Outcomes, March 7, 2019. https://doi.org/10.1093/ehjqcco/qcz010.
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  - Ahmad, Jawad, Simona Rossi, Shuchi K. Rodgers, Marwan Ghabril, Robert J. Fontana, Andrew Stolz, Paul H. Hayashi, Huiman Barnhart, David E. Kleiner, and Einar S. Bjornsson. “Sclerosing Cholangitis-Like Changes on Magnetic Resonance Cholangiography in Patients With Drug Induced Liver Injury..” Clinical Gastroenterology and Hepatology : The Official Clinical Practice Journal of the American Gastroenterological Association 17, no. 4 (March 2019): 789–90. https://doi.org/10.1016/j.cgh.2018.06.035.
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  - Daubert, Melissa A., Kirkwood Adams, Eric Yow, Huiman X. Barnhart, Pamela S. Douglas, Susan Rimmer, Casey Norris, et al. “NT-proBNP Goal Achievement Is Associated With Significant Reverse Remodeling and Improved Clinical Outcomes in HFrEF..” Jacc. Heart Failure 7, no. 2 (February 2019): 158–68. https://doi.org/10.1016/j.jchf.2018.10.014.
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  - Fontana, Robert John, Elizabeth Theresa Cirulli, Jiezhun Gu, David Kleiner, David Ostrov, Elizabeth Phillips, Ryan Schutte, et al. “The role of HLA-A*33:01 in patients with cholestatic hepatitis attributed to terbinafine..” Journal of Hepatology 69, no. 6 (December 2018): 1317–25. https://doi.org/10.1016/j.jhep.2018.08.004.
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  - Li, Zixiao, Xianwei Wang, Huiman Xie Barnhart, and Yongjun Wang. “Working With Statisticians in Clinical Research..” Stroke 49, no. 11 (November 2018): e311–13. https://doi.org/10.1161/strokeaha.118.022266.
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  - Diamantidis, Clarissa J., Hayden B. Bosworth, Megan M. Oakes, Clemontina A. Davenport, Jane F. Pendergast, Sejal Patel, Jivan Moaddeb, et al. “Simultaneous Risk Factor Control Using Telehealth to slOw Progression of Diabetic Kidney Disease (STOP-DKD) study: Protocol and baseline characteristics of a randomized controlled trial..” Contemp Clin Trials 69 (June 2018): 28–39. https://doi.org/10.1016/j.cct.2018.04.003.
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  - Khouri, Michel G., Bonnie Ky, Gary Dunn, Ted Plappert, Virginia Englefield, Dawn Rabineau, Eric Yow, Huiman X. Barnhart, Martin St John Sutton, and Pamela S. Douglas. “Echocardiography Core Laboratory Reproducibility of Cardiac Safety Assessments in Cardio-Oncology..” J Am Soc Echocardiogr 31, no. 3 (March 2018): 361-371.e3. https://doi.org/10.1016/j.echo.2017.11.018.
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  - Tyson, Crystal C., Huiman Barnhart, Shelly Sapp, Victor Poon, Pao-Hwa Lin, and Laura P. Svetkey. “Ambulatory blood pressure in the dash diet trial: Effects of race and albuminuria..” J Clin Hypertens (Greenwich) 20, no. 2 (February 2018): 308–14. https://doi.org/10.1111/jch.13170.
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  - Bonkovsky, Herbert L., Huiman X. Barnhart, David M. Foureau, Nury Steuerwald, William M. Lee, Jiezhun Gu, Robert J. Fontana, et al. “Cytokine profiles in acute liver injury-Results from the US Drug-Induced Liver Injury Network (DILIN) and the Acute Liver Failure Study Group..” Plos One 13, no. 10 (January 2018). https://doi.org/10.1371/journal.pone.0206389.
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  - Ahmad, Jawad, Joseph A. Odin, Paul H. Hayashi, Naga Chalasani, Robert J. Fontana, Huiman Barnhart, Elizabeth T. Cirulli, David E. Kleiner, and Jay H. Hoofnagle. “Identification and Characterization of Fenofibrate-Induced Liver Injury..” Dig Dis Sci 62, no. 12 (December 2017): 3596–3604. https://doi.org/10.1007/s10620-017-4812-7.
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  - Daubert, Melissa A., Eric Yow, Gary Dunn, Sotir Marchev, Huiman Barnhart, Pamela S. Douglas, Christopher O’Connor, Sidney Goldstein, James E. Udelson, and Hani N. Sabbah. “Novel Mitochondria-Targeting Peptide in Heart Failure Treatment: A Randomized, Placebo-Controlled Trial of Elamipretide..” Circ Heart Fail 10, no. 12 (December 2017). https://doi.org/10.1161/CIRCHEARTFAILURE.117.004389.
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  - Zullig, Leah L., Clarissa J. Diamantidis, Hayden B. Bosworth, Manjushri V. Bhapkar, Huiman Barnhart, Megan M. Oakes, Jane F. Pendergast, Julie J. Miller, and Uptal D. Patel. “Racial differences in nocturnal dipping status in diabetic kidney disease: Results from the STOP-DKD (Simultaneous Risk Factor Control Using Telehealth to Slow Progression of Diabetic Kidney Disease) study..” J Clin Hypertens (Greenwich) 19, no. 12 (December 2017): 1327–35. https://doi.org/10.1111/jch.13088.
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  - Suzuki, Ayako, Huiman Barnhart, Jiezhun Gu, Herbert L. Bonkovsky, Hans L. Tillmann, Robert J. Fontana, David E. Kleiner, and David E. Drug-induced Liver Injury Network (DILIN). “Associations of gender and a proxy of female menopausal status with histological features of drug-induced liver injury..” Liver Int 37, no. 11 (November 2017): 1723–30. https://doi.org/10.1111/liv.13380.
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  - Hayashi, Paul H., Don C. Rockey, Robert J. Fontana, Hans L. Tillmann, Neil Kaplowitz, Huiman X. Barnhart, Jiezhan Gu, et al. “Death and liver transplantation within 2 years of onset of drug-induced liver injury..” Hepatology 66, no. 4 (October 2017): 1275–85. https://doi.org/10.1002/hep.29283.
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  - Chalasani, Naga, K Rajender K. Reddy, Robert J. Fontana, Huiman Barnhart, Jiezhun Gu, Paul H. Hayashi, Jawad Ahmad, Andrew Stolz, Victor Navarro, and Jay H. Hoofnagle. “Idiosyncratic Drug Induced Liver Injury in African-Americans Is Associated With Greater Morbidity and Mortality Compared to Caucasians..” Am J Gastroenterol 112, no. 9 (September 2017): 1382–88. https://doi.org/10.1038/ajg.2017.215.
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  - Wang, Xianwei, Yilong Wang, Uptal D. Patel, Huiman Xie Barnhart, Zixiao Li, Hao Li, Chunxue Wang, et al. “Comparison of Associations of Reduced Estimated Glomerular Filtration Rate With Stroke Outcomes Between Hypertension and No Hypertension..” Stroke 48, no. 6 (June 2017): 1691–94. https://doi.org/10.1161/STROKEAHA.117.016864.
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  - Bonkovsky, Herbert L., David E. Kleiner, Jiezhun Gu, Joseph A. Odin, Mark W. Russo, Victor M. Navarro, Robert J. Fontana, et al. “Clinical presentations and outcomes of bile duct loss caused by drugs and herbal and dietary supplements..” Hepatology 65, no. 4 (April 2017): 1267–77. https://doi.org/10.1002/hep.28967.
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  - Nicoletti, Paola, Guruprasad P. Aithal, Einar S. Bjornsson, Raul J. Andrade, Ashley Sawle, Marco Arrese, Huiman X. Barnhart, et al. “Association of Liver Injury From Specific Drugs, or Groups of Drugs, With Polymorphisms in HLA and Other Genes in a Genome-Wide Association Study..” Gastroenterology 152, no. 5 (April 2017): 1078–89. https://doi.org/10.1053/j.gastro.2016.12.016.
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  - Pan, Yi, and Huiman X. Barnhart. “Methods for assessing the reliability of quality of life based on SF-36..” Stat Med 35, no. 30 (December 30, 2016): 5656–65. https://doi.org/10.1002/sim.7085.
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  - Barnhart, Huiman X., Eric Yow, Anna Lisa Crowley, Melissa A. Daubert, Dawn Rabineau, Robert Bigelow, Michael Pencina, and Pamela S. Douglas. “Choice of agreement indices for assessing and improving measurement reproducibility in a core laboratory setting..” Stat Methods Med Res 25, no. 6 (December 2016): 2939–58. https://doi.org/10.1177/0962280214534651.
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  - Crowley, Anna Lisa, Eric Yow, Huiman X. Barnhart, Melissa A. Daubert, Robert Bigelow, Daniel C. Sullivan, Michael Pencina, and Pamela S. Douglas. “Critical Review of Current Approaches for Echocardiographic Reproducibility and Reliability Assessment in Clinical Research..” J Am Soc Echocardiogr 29, no. 12 (December 2016): 1144-1154.e7. https://doi.org/10.1016/j.echo.2016.08.006.
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  - Barnhart, Huiman X. “Assessing agreement with relative area under the coverage probability curve..” Stat Med 35, no. 18 (August 15, 2016): 3153–65. https://doi.org/10.1002/sim.6903.
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  - Tyson, Crystal C., Pao-Hwa Lin, Leonor Corsino, Bryan C. Batch, Jenifer Allen, Shelly Sapp, Huiman Barnhart, Chinazo Nwankwo, Jasmine Burroughs, and Laura P. Svetkey. “Short-term effects of the DASH diet in adults with moderate chronic kidney disease: a pilot feeding study..” Clin Kidney J 9, no. 4 (August 2016): 592–98. https://doi.org/10.1093/ckj/sfw046.
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  - deLemos, Andrew S., Marwan Ghabril, Don C. Rockey, Jiezhun Gu, Huiman X. Barnhart, Robert J. Fontana, David E. Kleiner, Herbert L. Bonkovsky, and Herbert L. Drug-Induced Liver Injury Network (DILIN). “Amoxicillin-Clavulanate-Induced Liver Injury..” Dig Dis Sci 61, no. 8 (August 2016): 2406–16. https://doi.org/10.1007/s10620-016-4121-6.
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  - Lauridsen, Trine Kiilerich, Christine Selton-Suty, Steven Tong, Luis Afonso, Enrico Cecchi, Lawrence Park, Eric Yow, et al. “Echocardiographic agreement in the diagnostic evaluation for infective endocarditis..” Int J Cardiovasc Imaging 32, no. 7 (July 2016): 1041–51. https://doi.org/10.1007/s10554-016-0873-5.
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  - Burke, Christopher John, Manjiri M. Didolkar, Huiman X. Barnhart, and Emily N. Vinson. “The use of routine non density calibrated clinical computed tomography data as a potentially useful screening tool for identifying patients with osteoporosis..” Clin Cases Miner Bone Metab 13, no. 2 (May 2016): 135–40. https://doi.org/10.11138/ccmbm/2016.13.2.135.
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  - Obuchowski, Nancy A., Andrew Buckler, Paul Kinahan, Heather Chen-Mayer, Nicholas Petrick, Daniel P. Barboriak, Jennifer Bullen, Huiman Barnhart, and Daniel C. Sullivan. “Statistical Issues in Testing Conformance with the Quantitative Imaging Biomarker Alliance (QIBA) Profile Claims..” Acad Radiol 23, no. 4 (April 2016): 496–506. https://doi.org/10.1016/j.acra.2015.12.020.
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  - Lin, Lawrence, Yi Pan, A. S. Hedayat, Huiman X. Barnhart, and Michael Haber. “A simulation study of nonparametric total deviation index as a measure of agreement based on quantile regression..” J Biopharm Stat 26, no. 5 (2016): 937–50. https://doi.org/10.1080/10543406.2015.1094812.
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  - Lyles, Robert H., Lawrence L. Kupper, Huiman X. Barnhart, and Sandra L. Martin. “Numeric score-based conditional and overall change-in-status indices for ordered categorical data..” Stat Med 34, no. 27 (November 30, 2015): 3622–36. https://doi.org/10.1002/sim.6559.
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  - Fontana, Robert J., Paul H. Hayashi, Huiman Barnhart, David E. Kleiner, K Rajender Reddy, Naga Chalasani, William M. Lee, et al. “Persistent liver biochemistry abnormalities are more common in older patients and those with cholestatic drug induced liver injury..” Am J Gastroenterol 110, no. 10 (October 2015): 1450–59. https://doi.org/10.1038/ajg.2015.283.
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  - Uller, Wibke, and Ahmad I. Alomari. “Abernethy Malformation..” Radiographics 35, no. 5 (September 2015). https://doi.org/10.1148/rg.2015150089.
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  - Hayes, M Geoffrey, Margrit Urbanek, David A. Ehrmann, Loren L. Armstrong, Ji Young Lee, Ryan Sisk, Tugce Karaderi, et al. “Genome-wide association of polycystic ovary syndrome implicates alterations in gonadotropin secretion in European ancestry populations..” Nat Commun 6 (August 18, 2015). https://doi.org/10.1038/ncomms8502.
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  - Daubert, Melissa A., Eric Yow, Huiman X. Barnhart, Dawn Rabineau, Anna Lisa Crowley, and Pamela S. Douglas. “Quality Improvement Implementation: Improving Reproducibility in the Echocardiography Laboratory..” J Am Soc Echocardiogr 28, no. 8 (August 2015): 959–68. https://doi.org/10.1016/j.echo.2015.03.004.
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  - Chalasani, Naga, Herbert L. Bonkovsky, Robert Fontana, William Lee, Andrew Stolz, Jayant Talwalkar, K Rajendar Reddy, et al. “Features and Outcomes of 899 Patients With Drug-Induced Liver Injury: The DILIN Prospective Study..” Gastroenterology 148, no. 7 (June 2015): 1340-52.e7. https://doi.org/10.1053/j.gastro.2015.03.006.
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  - Forsha, Daniel, Niels Risum, Sudarshan Rajagopal, Stephen Dolgner, Christoph Hornik, Huiman Barnhart, Joseph Kisslo, and Piers Barker. “The influence of angle of insonation and target depth on speckle-tracking strain..” J Am Soc Echocardiogr 28, no. 5 (May 2015): 580–86. https://doi.org/10.1016/j.echo.2014.12.015.
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  - Hayashi, Paul H., Huiman X. Barnhart, Robert J. Fontana, Naga Chalasani, Timothy J. Davern, Jayant A. Talwalkar, K Rajender Reddy, Andrew A. Stolz, Jay H. Hoofnagle, and Don C. Rockey. “Reliability of causality assessment for drug, herbal and dietary supplement hepatotoxicity in the Drug-Induced Liver Injury Network (DILIN)..” Liver Int 35, no. 5 (May 2015): 1623–32. https://doi.org/10.1111/liv.12540.
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  - Kessler, Larry G., Huiman X. Barnhart, Andrew J. Buckler, Kingshuk Roy Choudhury, Marina V. Kondratovich, Alicia Toledano, Alexander R. Guimaraes, et al. “The emerging science of quantitative imaging biomarkers terminology and definitions for scientific studies and regulatory submissions..” Stat Methods Med Res 24, no. 1 (February 2015): 9–26. https://doi.org/10.1177/0962280214537333.
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  - Obuchowski, Nancy A., Anthony P. Reeves, Erich P. Huang, Xiao-Feng Wang, Andrew J. Buckler, Hyun J Grace Kim, Huiman X. Barnhart, et al. “Quantitative imaging biomarkers: a review of statistical methods for computer algorithm comparisons..” Stat Methods Med Res 24, no. 1 (February 2015): 68–106. https://doi.org/10.1177/0962280214537390.
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  - Obuchowski, Nancy A., Huiman X. Barnhart, Andrew J. Buckler, Gene Pennello, Xiao-Feng Wang, Jayashree Kalpathy-Cramer, Hyun J Grace Kim, Anthony P. Reeves, and Anthony P. Case Example Working Group. “Statistical issues in the comparison of quantitative imaging biomarker algorithms using pulmonary nodule volume as an example..” Stat Methods Med Res 24, no. 1 (February 2015): 107–40. https://doi.org/10.1177/0962280214537392.
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  - Price, Elizabeth, Andrew S. Artz, Huiman Barnhart, Shelly Sapp, Gordon Chelune, William B. Ershler, Jeremy D. Walston, et al. “A prospective randomized wait list control trial of intravenous iron sucrose in older adults with unexplained anemia and serum ferritin 20-200 ng/mL..” Blood Cells Mol Dis 53, no. 4 (December 2014): 221–30. https://doi.org/10.1016/j.bcmd.2014.06.003.
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  - Navarro, Victor J., Huiman Barnhart, Herbert L. Bonkovsky, Timothy Davern, Robert J. Fontana, Lafaine Grant, K Rajender Reddy, et al. “Liver injury from herbals and dietary supplements in the U.S. Drug-Induced Liver Injury Network..” Hepatology 60, no. 4 (October 2014): 1399–1408. https://doi.org/10.1002/hep.27317.
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  - Russo, Mark W., Jay H. Hoofnagle, Jiezhun Gu, Robert J. Fontana, Huiman Barnhart, David E. Kleiner, Naga Chalasani, and Herbert L. Bonkovsky. “Spectrum of statin hepatotoxicity: experience of the drug-induced liver injury network..” Hepatology 60, no. 2 (August 2014): 679–86. https://doi.org/10.1002/hep.27157.
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  - Fontana, Robert J., Paul H. Hayashi, Jiezhun Gu, K Rajender Reddy, Huiman Barnhart, Paul B. Watkins, Jose Serrano, et al. “Idiosyncratic drug-induced liver injury is associated with substantial morbidity and mortality within 6 months from onset..” Gastroenterology 147, no. 1 (July 2014): 96-108.e4. https://doi.org/10.1053/j.gastro.2014.03.045.
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  - Ardoin, Stacy P., Laura Eve Schanberg, Christy I. Sandborg, Huiman X. Barnhart, Greg W. Evans, Eric Yow, Kelly L. Mieszkalski, et al. “Secondary analysis of APPLE study suggests atorvastatin may reduce atherosclerosis progression in pubertal lupus patients with higher C reactive protein..” Ann Rheum Dis 73, no. 3 (March 2014): 557–66. https://doi.org/10.1136/annrheumdis-2012-202315.
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  - Kleiner, David E., Naga P. Chalasani, William M. Lee, Robert J. Fontana, Herbert L. Bonkovsky, Paul B. Watkins, Paul H. Hayashi, et al. “Hepatic histological findings in suspected drug-induced liver injury: systematic evaluation and clinical associations..” Hepatology 59, no. 2 (February 2014): 661–70. https://doi.org/10.1002/hep.26709.
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  - Kleiner, D. E., N. P. Chalasani, W. M. Lee, R. J. Fontana, H. L. Bonkovsky, P. B. Watkins, P. H. Hayashi, et al. “Hepatic histological findings in suspected drug-induced liver injury: Systematic evaluation and clinical associations.” Hepatology 59, no. 2 (2014): 661–70. https://doi.org/10.1002/hep.26709.
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  - Chen, Baiyu, Huiman Barnhart, Samuel Richard, Marthony Robins, James Colsher, and Ehsan Samei. “Volumetric quantification of lung nodules in CT with iterative reconstruction (ASiR and MBIR)..” Med Phys 40, no. 11 (November 2013). https://doi.org/10.1118/1.4823463.
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  - Navarro, Victor J., Herbert L. Bonkovsky, Sun-Il Hwang, Maricruz Vega, Huiman Barnhart, and Jose Serrano. “Catechins in dietary supplements and hepatotoxicity..” Dig Dis Sci 58, no. 9 (September 2013): 2682–90. https://doi.org/10.1007/s10620-013-2687-9.
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  - Chen, Baiyu, Daniele Marin, Samuel Richard, Daniela Husarik, Rendon Nelson, and Ehsan Samei. “Precision of iodine quantification in hepatic CT: effects of iterative reconstruction with various imaging parameters..” Ajr Am J Roentgenol 200, no. 5 (May 2013): W475–82. https://doi.org/10.2214/AJR.12.9658.
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  - Chen, C. C., and H. X. Barnhart. “Assessing agreement with intraclass correlation coefficient and concordance correlation coefficient for data with repeated measures.” Computational Statistics and Data Analysis 60, no. 1 (January 1, 2013): 132–45. https://doi.org/10.1016/j.csda.2012.11.004.
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  - McCullough, Peter A., Huiman X. Barnhart, Jula K. Inrig, Donal Reddan, Shelly Sapp, Uptal D. Patel, Ajay K. Singh, Lynda A. Szczech, and Robert M. Califf. “Cardiovascular toxicity of epoetin-alfa in patients with chronic kidney disease..” Am J Nephrol 37, no. 6 (2013): 549–58. https://doi.org/10.1159/000351175.
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  - Steuerwald, Nury M., David M. Foureau, H James Norton, Jie Zhou, Judith C. Parsons, Naga Chalasani, Robert J. Fontana, et al. “Profiles of serum cytokines in acute drug-induced liver injury and their prognostic significance..” Plos One 8, no. 12 (2013). https://doi.org/10.1371/journal.pone.0081974.
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  - Wang, Zongyao, John S. Sundy, Catherine M. Foss, Huiman X. Barnhart, Scott M. Palmer, Sallie D. Allgood, Evan Trudeau, Katie M. Alexander, and Marc C. Levesque. “Racial differences in the association of CD14 polymorphisms with serum total IgE levels and allergen skin test reactivity..” J Asthma Allergy 6 (2013): 81–92. https://doi.org/10.2147/JAA.S42695.
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  - Daubert, Melissa A., Huiman X. Barnhart, Eric Yow, Dawn Rabineau, and Pamela S. Douglas. “A Practical Approach to Quality Assurance Implementation in Clinical Echocardiographic Laboratories.” Circulation 126, no. 21 (November 20, 2012).
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  - Pan, Yi, Michael Haber, Jingjing Gao, and Huiman X. Barnhart. “A new permutation-based method for assessing agreement between two observers making replicated quantitative readings..” Stat Med 31, no. 20 (September 10, 2012): 2249–61. https://doi.org/10.1002/sim.5323.
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  - Inrig, Jula K., Huiman X. Barnhart, Donal Reddan, Uptal D. Patel, Shelly Sapp, Robert M. Califf, Ajay K. Singh, and Lynda A. Szczech. “Effect of hemoglobin target on progression of kidney disease: a secondary analysis of the CHOIR (Correction of Hemoglobin and Outcomes in Renal Insufficiency) trial..” Am J Kidney Dis 60, no. 3 (September 2012): 390–401. https://doi.org/10.1053/j.ajkd.2012.03.009.
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  - Inrig, Jula K., Shelly Sapp, Huiman Barnhart, Uptal D. Patel, Donal Reddan, Ajay Singh, Robert M. Califf, and Lynda Szczech. “Impact of higher hemoglobin targets on blood pressure and clinical outcomes: a secondary analysis of CHOIR..” Nephrol Dial Transplant 27, no. 9 (September 2012): 3606–14. https://doi.org/10.1093/ndt/gfs123.
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  - Lungren, Matthew P., Eshan Samei, Huiman Barnhart, H Page McAdams, Richard A. Leder, Jared D. Christensen, John D. Wylie, Jin W. Tan, Xiang Li, and Lynne M. Hurwitz. “Gray-scale inversion radiographic display for the detection of pulmonary nodules on chest radiographs..” Clin Imaging 36, no. 5 (September 2012): 515–21. https://doi.org/10.1016/j.clinimag.2012.01.009.
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  - Ardoin, S. P., G. Evans, C. Sandborg, H. X. Barnhart, and L. E. Schanberg. “Reply.” Arthritis and Rheumatism 64, no. 8 (August 1, 2012): 2805–6. https://doi.org/10.1002/art.34518.
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  - Mazurowski, Maciej A., Huiman X. Barnhart, Jay A. Baker, and Georgia D. Tourassi. “Identifying error-making patterns in assessment of mammographic BI-RADS descriptors among radiology residents using statistical pattern recognition..” Acad Radiol 19, no. 7 (July 2012): 865–71. https://doi.org/10.1016/j.acra.2012.01.012.
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  - Chalasani, Naga, Raj Vuppalanchi, Victor Navarro, Robert Fontana, Herbert Bonkovsky, Huiman Barnhart, David E. Kleiner, and Jay H. Hoofnagle. “Acute liver injury due to flavocoxid (Limbrel), a medical food for osteoarthritis: a case series..” Ann Intern Med 156, no. 12 (June 19, 2012): 857-W300. https://doi.org/10.7326/0003-4819-156-12-201206190-00006.
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  - Ho, Lisa M., Daniele Marin, Amy M. Neville, Huiman X. Barnhart, Rajan T. Gupta, Erik K. Paulson, and Daniel T. Boll. “Characterization of adrenal nodules with dual-energy CT: can virtual unenhanced attenuation values replace true unenhanced attenuation values?.” Ajr Am J Roentgenol 198, no. 4 (April 2012): 840–45. https://doi.org/10.2214/AJR.11.7316.
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  - Chen, Baiyu, Huiman Barnhart, Samuel Richard, James Colsher, Maxwell Amurao, and Ehsan Samei. “Quantitative CT: technique dependence of volume estimation on pulmonary nodules..” Phys Med Biol 57, no. 5 (March 7, 2012): 1335–48. https://doi.org/10.1088/0031-9155/57/5/1335.
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  - Allen, Brian C., Huiman Barnhart, Mustafa Bashir, Christopher Nieman, Steven Breault, and Tracy A. Jaffe. “Diagnostic accuracy of intra-abdominal fluid collection characterization in the era of multidetector computed tomography..” Am Surg 78, no. 2 (February 2012): 185–89.
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  - Schanberg, L. E., C. Sandborg, H. X. Barnhart, S. P. Ardoin, E. Yow, G. W. Evans, K. L. Mieszkalski, et al. “Use of atorvastatin in systemic lupus erythematosus in children and adolescents..” Arthritis Rheum 64, no. 1 (January 2012): 285–96. https://doi.org/10.1002/art.30645.
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  - Chen, Chia-Cheng, and Huiman X. Barnhart. “Assessing agreement with repeated measures for random observers..” Stat Med 30, no. 30 (December 30, 2011): 3546–59. https://doi.org/10.1002/sim.4353.
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  - Patel, Manesh R., Richard W. Smalling, Holger Thiele, Huiman X. Barnhart, Yi Zhou, Praveen Chandra, Derek Chew, et al. “Intra-aortic balloon counterpulsation and infarct size in patients with acute anterior myocardial infarction without shock: the CRISP AMI randomized trial..” Jama 306, no. 12 (September 28, 2011): 1329–37. https://doi.org/10.1001/jama.2011.1280.
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  - Marin, Daniele, Rendon C. Nelson, Antonino Guerrisi, Huiman Barnhart, Sebastian T. Schindera, Roberto Passariello, and Carlo Catalano. “64-section multidetector CT of the upper abdomen: optimization of a saline chaser injection protocol for improved vascular and parenchymal contrast enhancement..” Eur Radiol 21, no. 9 (September 2011): 1938–47. https://doi.org/10.1007/s00330-011-2139-x.
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  - Guerrisi, A., D. Marin, R. C. Nelson, G. De Filippis, M. Di Martino, H. Barnhart, R. Masciangelo, I. Guerrisi, R. Passariello, and C. Catalano. “Effect of varying contrast material iodine concentration and injection technique on the conspicuity of hepatocellular carcinoma during 64-section MDCT of patients with cirrhosis..” Br J Radiol 84, no. 1004 (August 2011): 698–708. https://doi.org/10.1259/bjr/21539234.
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  - Lessne, Mark L., Pratish Shah, Michael J. Alexander, Huiman X. Barnhart, Ciaran J. Powers, Kiarash Golshani, Andrew Ferrell, et al. “Thromboembolic complications after Neuroform stent-assisted treatment of cerebral aneurysms: the Duke Cerebrovascular Center experience in 235 patients with 274 stents..” Neurosurgery 69, no. 2 (August 2011): 369–75. https://doi.org/10.1227/NEU.0b013e31821bc49c.
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  - Kilani, Ramsey K., Ben E. Paxton, Sandra S. Stinnett, Huiman X. Barnhart, Vishal Bindal, and Matthew P. Lungren. “Self-referral in medical imaging: a meta-analysis of the literature..” J Am Coll Radiol 8, no. 7 (July 2011): 469–76. https://doi.org/10.1016/j.jacr.2011.01.016.
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  - Li, Xiang, Ehsan Samei, Huiman X. Barnhart, Ana Maria Gaca, Caroline L. Hollingsworth, Charles M. Maxfield, Caroline W. T. Carrico, James G. Colsher, and Donald P. Frush. “Lung nodule detection in pediatric chest CT: quantitative relationship between image quality and radiologist performance..” Med Phys 38, no. 5 (May 2011): 2609–18. https://doi.org/10.1118/1.3582975.
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  - Pan, Yi, Michael Haber, and Huiman X. Barnhart. “A new permutation-based method for assessing agreement between two observers making replicated binary readings..” Stat Med 30, no. 8 (April 15, 2011): 839–53. https://doi.org/10.1002/sim.4136.
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  - Ardoin, S. P., L. E. Schanberg, C. Sandborg, E. Yow, H. X. Barnhart, K. L. Mieszkalski, N. T. Ilowite, et al. “Laboratory markers of cardiovascular risk in pediatric SLE: the APPLE baseline cohort..” Lupus 19, no. 11 (October 2010): 1315–25. https://doi.org/10.1177/0961203310373937.
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  - Pagidas, Kelly, Sandra A. Carson, Peter G. McGovern, Huiman X. Barnhart, Evan R. Myers, Richard S. Legro, Michael P. Diamond, et al. “Intercourse compliance, ovulation, and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome (PPCOS) Trial..” Fertil Steril 94, no. 4 (September 2010): 1444–46. https://doi.org/10.1016/j.fertnstert.2009.05.047.
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  - Pagidas, Kelly, Sandra A. Carson, Peter G. McGovern, Huiman X. Barnhart, Evan R. Myers, Richard S. Legro, Michael P. Diamond, et al. “Body mass index and intercourse compliance..” Fertil Steril 94, no. 4 (September 2010): 1447–50. https://doi.org/10.1016/j.fertnstert.2009.05.048.
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  - Marin, Daniele, Rendon C. Nelson, Huiman Barnhart, Sebastian T. Schindera, Lisa M. Ho, Tracy A. Jaffe, Terry T. Yoshizumi, Richard Youngblood, and Ehsan Samei. “Detection of pancreatic tumors, image quality, and radiation dose during the pancreatic parenchymal phase: effect of a low-tube-voltage, high-tube-current CT technique--preliminary results..” Radiology 256, no. 2 (August 2010): 450–59. https://doi.org/10.1148/radiol.10091819.
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  - Gupta, Rajan T., Lisa M. Ho, Daniele Marin, Daniel T. Boll, Huiman X. Barnhart, and Rendon C. Nelson. “Dual-energy CT for characterization of adrenal nodules: initial experience..” Ajr Am J Roentgenol 194, no. 6 (June 2010): 1479–83. https://doi.org/10.2214/AJR.09.3476.
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  - Pan, Yi, Jingjing Gao, Michael Haber, and Huiman X. Barnhart. “Estimation of coefficients of individual agreement (CIAs) for quantitative and binary data using SAS and R..” Comput Methods Programs Biomed 98, no. 2 (May 2010): 214–19. https://doi.org/10.1016/j.cmpb.2009.12.002.
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  - Cutler, S. J., K. L. Perez, H. X. Barnhart, and M. P. Tornai. “Observer detection limits for a dedicated SPECT breast imaging system..” Phys Med Biol 55, no. 7 (April 7, 2010): 1903–16. https://doi.org/10.1088/0031-9155/55/7/008.
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  - Mazurowski, Maciej A., Jay A. Baker, Huiman X. Barnhart, and Georgia D. Tourassi. “Individualized computer-aided education in mammography based on user modeling: concept and preliminary experiments..” Med Phys 37, no. 3 (March 2010): 1152–60. https://doi.org/10.1118/1.3301575.
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  - Gaca, Ana Maria, Huiman X. Barnhart, and George S. Bisset. “Evaluation of wedging of lower thoracic and upper lumbar vertebral bodies in the pediatric population..” Ajr Am J Roentgenol 194, no. 2 (February 2010): 516–20. https://doi.org/10.2214/AJR.09.3065.
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  - Marin, Daniele, Lisa M. Ho, Huiman Barnhart, Amy M. Neville, Rebekah R. White, and Erik K. Paulson. “Percutaneous abscess drainage in patients with perforated acute appendicitis: effectiveness, safety, and prediction of outcome..” Ajr Am J Roentgenol 194, no. 2 (February 2010): 422–29. https://doi.org/10.2214/AJR.09.3098.
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  - Szczech, Lynda A., Huiman X. Barnhart, Shelly Sapp, G Michael Felker, Adrian Hernandez, Donal Reddan, Robert M. Califf, Jula K. Inrig, Uptal D. Patel, and Ajay K. Singh. “A secondary analysis of the CHOIR trial shows that comorbid conditions differentially affect outcomes during anemia treatment..” Kidney Int 77, no. 3 (February 2010): 239–46. https://doi.org/10.1038/ki.2009.415.
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  - Rausch, M. E., R. S. Legro, H. X. Barnhart, W. D. Schlaff, B. R. Carr, M. P. Diamond, S. A. Carson, et al. “Predictors of pregnancy in women with polycystic ovary syndrome.” Obstetrical and Gynecological Survey 65, no. 1 (January 1, 2010): 30–32. https://doi.org/10.1097/01.ogx.0000367515.48912.b1.
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  - Barnhart, Huiman X., and Daniel P. Barboriak. “Applications of the repeatability of quantitative imaging biomarkers: a review of statistical analysis of repeat data sets..” Transl Oncol 2, no. 4 (December 2009): 231–35. https://doi.org/10.1593/tlo.09268.
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  - Rausch, Mary E., Richard S. Legro, Huiman X. Barnhart, William D. Schlaff, Bruce R. Carr, Michael P. Diamond, Sandra A. Carson, et al. “Predictors of pregnancy in women with polycystic ovary syndrome..” J Clin Endocrinol Metab 94, no. 9 (September 2009): 3458–66. https://doi.org/10.1210/jc.2009-0545.
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  - Schanberg, Laura E., Christy Sandborg, Huiman X. Barnhart, Stacy P. Ardoin, Eric Yow, Gregory W. Evans, Kelly L. Mieszkalski, et al. “Premature atherosclerosis in pediatric systemic lupus erythematosus: risk factors for increased carotid intima-media thickness in the atherosclerosis prevention in pediatric lupus erythematosus cohort..” Arthritis Rheum 60, no. 5 (May 2009): 1496–1507. https://doi.org/10.1002/art.24469.
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  - Chen, C. C., and H. X. Barnhart. “Comparison of ICC and CCC for assessing agreement for data without and with replications.” Computational Statistics and Data Analysis 53, no. 2 (December 15, 2008): 554–64. https://doi.org/10.1016/j.csda.2008.09.026.
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  - May, Chris, and Huiman X. Barnhart. “Use of concordance correlation coefficient in objective and subjective assessment of limb function..” Vet Surg 37, no. 7 (October 2008): 706–7. https://doi.org/10.1111/j.1532-950X.2008.00453.x.
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  - McGovern, Peter G., Sandra A. Carson, Huiman X. Barnhart, Evan R. Myers, Richard S. Legro, Michael P. Diamond, Bruce R. Carr, et al. “Medication adherence and treatment success in the National Institute of Child Health and Human Development-Reproductive Medicine Network's Pregnancy in Polycystic Ovary Syndrome Trial..” Fertil Steril 90, no. 4 (October 2008): 1283–86. https://doi.org/10.1016/j.fertnstert.2007.09.004.
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  - Szczech, Lynda A., Huiman X. Barnhart, Jula K. Inrig, Donal N. Reddan, Shelly Sapp, Robert M. Califf, Uptal D. Patel, and Ajay K. Singh. “Secondary analysis of the CHOIR trial epoetin-alpha dose and achieved hemoglobin outcomes..” Kidney Int 74, no. 6 (September 2008): 791–98. https://doi.org/10.1038/ki.2008.295.
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  - Cataldo, Nicholas A., Huiman X. Barnhart, Richard S. Legro, Evan R. Myers, William D. Schlaff, Bruce R. Carr, Michael P. Diamond, et al. “Extended-release metformin does not reduce the clomiphene citrate dose required to induce ovulation in polycystic ovary syndrome..” J Clin Endocrinol Metab 93, no. 8 (August 2008): 3124–27. https://doi.org/10.1210/jc.2008-0287.
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  - Haber, Michael, and Huiman X. Barnhart. “A general approach to evaluating agreement between two observers or methods of measurement from quantitative data with replicated measurements..” Stat Methods Med Res 17, no. 2 (April 2008): 151–69. https://doi.org/10.1177/0962280206075527.
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  - Trimble, Mark A., Eric J. Velazquez, George L. Adams, Emily F. Honeycutt, Robert A. Pagnanelli, Huiman X. Barnhart, Ji Chen, Ami E. Iskandrian, Ernest V. Garcia, and Salvador Borges-Neto. “Repeatability and reproducibility of phase analysis of gated single-photon emission computed tomography myocardial perfusion imaging used to quantify cardiac dyssynchrony..” Nucl Med Commun 29, no. 4 (April 2008): 374–81. https://doi.org/10.1097/MNM.0b013e3282f81380.
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  - Legro, Richard S., Huiman X. Barnhart, William D. Schlaff, Bruce R. Carr, Michael P. Diamond, Sandra A. Carson, Michael P. Steinkampf, et al. “Ovulatory response to treatment of polycystic ovary syndrome is associated with a polymorphism in the STK11 gene..” J Clin Endocrinol Metab 93, no. 3 (March 2008): 792–800. https://doi.org/10.1210/jc.2007-1736.
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  - Jung, Sin-Ho, Huiman X. Barnhart, Insuk Sohn, Sandra S. Stinnett, and David K. Wallace. “Sample size for comparing correlated concordance rates..” J Biopharm Stat 18, no. 2 (2008): 359–69. https://doi.org/10.1080/10543400701697216.
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  - Crawford, Sara B., Andrzej S. Kosinski, Hung-Mo Lin, John M. Williamson, and Huiman X. Barnhart. “Computer programs for the concordance correlation coefficient..” Comput Methods Programs Biomed 88, no. 1 (October 2007): 62–74. https://doi.org/10.1016/j.cmpb.2007.07.003.
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  - Barnhart, H. X. “Guest editor's note for the special issue on assessing agreement.” Journal of Biopharmaceutical Statistics 17, no. 4 (July 1, 2007): 525–27. https://doi.org/10.1080/10543400701376472.
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  - Singh, Ajay K., Lynda Szczech, Kezhen L. Tang, Huiman Barnhart, Shelly Sapp, Marsha Wolfson, and Donal Reddan. “Anaemia of CKD--the CHOIR study revisited..” Nephrol Dial Transplant 22, no. 7 (July 2007): 1806–10. https://doi.org/10.1093/ndt/gfm185.
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  - Legro, Richard S., Huiman X. Barnhart, William D. Schlaff, Bruce R. Carr, Michael P. Diamond, Sandra A. Carson, Michael P. Steinkampf, et al. “Clomiphene, metformin, or both for infertility in the polycystic ovary syndrome..” N Engl J Med 356, no. 6 (February 8, 2007): 551–66. https://doi.org/10.1056/NEJMoa063971.
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  - McGovern, Peter G., Richard S. Legro, Evan R. Myers, Huiman X. Barnhart, Sandra A. Carson, Michael P. Diamond, Bruce R. Carr, et al. “Utility of screening for other causes of infertility in women with "known" polycystic ovary syndrome..” Fertil Steril 87, no. 2 (February 2007): 442–44. https://doi.org/10.1016/j.fertnstert.2006.06.050.
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  - Barnhart, Huiman X., Andrzej S. Kosinski, and Michael J. Haber. “Assessing individual agreement..” J Biopharm Stat 17, no. 4 (2007): 697–719. https://doi.org/10.1080/10543400701329489.
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  - Barnhart, Huiman X., Michael J. Haber, and Lawrence I. Lin. “An overview on assessing agreement with continuous measurements..” J Biopharm Stat 17, no. 4 (2007): 529–69. https://doi.org/10.1080/10543400701376480.
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  - Barnhart, Huiman X., Yuliya Lokhnygina, Andrzej S. Kosinski, and Michael Haber. “Comparison of concordance correlation coefficient and coefficient of individual agreement in assessing agreement..” J Biopharm Stat 17, no. 4 (2007): 721–38. https://doi.org/10.1080/10543400701329497.
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  - Haber, Michael, Jingjing Gao, and Huiman X. Barnhart. “Assessing observer agreement in studies involving replicated binary observations..” J Biopharm Stat 17, no. 4 (2007): 757–66. https://doi.org/10.1080/10543400701329547.
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  - Singh, Ajay K., Lynda Szczech, Kezhen L. Tang, Huiman Barnhart, Shelly Sapp, Marsha Wolfson, Donal Reddan, and Donal CHOIR Investigators. “Correction of anemia with epoetin alfa in chronic kidney disease..” N Engl J Med 355, no. 20 (November 16, 2006): 2085–98. https://doi.org/10.1056/NEJMoa065485.
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  - Legro, Richard S., Evan R. Myers, Huiman X. Barnhart, Sandra A. Carson, Michael P. Diamond, Bruce R. Carr, William D. Schlaff, et al. “The Pregnancy in Polycystic Ovary Syndrome study: baseline characteristics of the randomized cohort including racial effects..” Fertil Steril 86, no. 4 (October 2006): 914–33. https://doi.org/10.1016/j.fertnstert.2006.03.037.
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  - Lin, Carol Y., Huiman X. Barnhart, and Andrzej S. Kosinski. “The weighted generalized estimating equations approach for the evaluation of medical diagnostic test at subunit level..” Biom J 48, no. 5 (August 2006): 758–71.
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  - Kuklina, Elena V., Usha Ramakrishnan, Aryeh D. Stein, Huiman H. Barnhart, and Reynaldo Martorell. “Early childhood growth and development in rural Guatemala..” Early Hum Dev 82, no. 7 (July 2006): 425–33. https://doi.org/10.1016/j.earlhumdev.2005.10.018.
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  - Haber, Michael, and Huiman X. Barnhart. “Coefficients of agreement for fixed observers..” Stat Methods Med Res 15, no. 3 (June 2006): 255–71. https://doi.org/10.1191/0962280206sm441oa.
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  - Barnhart, Huiman X., Jingli Song, and Robert H. Lyles. “Assay validation for left-censored data..” Stat Med 24, no. 21 (November 15, 2005): 3347–60. https://doi.org/10.1002/sim.2225.
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  - Kutner, Nancy G., Rebecca Zhang, Huiman Barnhart, and Allan J. Collins. “Health status and quality of life reported by incident patients after 1 year on haemodialysis or peritoneal dialysis..” Nephrol Dial Transplant 20, no. 10 (October 2005): 2159–67. https://doi.org/10.1093/ndt/gfh973.
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  - Webb, Aimee L., Andrea J. Conlisk, Huiman X. Barnhart, Reynaldo Martorell, Rubén Grajeda, and Aryeh D. Stein. “Maternal and childhood nutrition and later blood pressure levels in young Guatemalan adults..” Int J Epidemiol 34, no. 4 (August 2005): 898–904. https://doi.org/10.1093/ije/dyi097.
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  - Barnhart, Huiman X., Jingli Song, and Michael J. Haber. “Assessing intra, inter and total agreement with replicated readings..” Stat Med 24, no. 9 (May 15, 2005): 1371–84. https://doi.org/10.1002/sim.2006.
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  - Kuklina, Elena V., Usha Ramakrishnan, Aryeh D. Stein, Huiman H. Barnhart, and Reynaldo Martorell. “Growth and diet quality are associated with the attainment of walking in rural Guatemalan infants..” J Nutr 134, no. 12 (December 2004): 3296–3300. https://doi.org/10.1093/jn/134.12.3296.
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  - Conlisk, Andrea J., Huiman X. Barnhart, Reynaldo Martorell, Ruben Grajeda, and Aryeh D. Stein. “Maternal and child nutritional supplementation are inversely associated with fasting plasma glucose concentration in young Guatemalan adults..” J Nutr 134, no. 4 (April 2004): 890–97. https://doi.org/10.1093/jn/134.4.890.
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  - Stein, Aryeh D., Huiman X. Barnhart, Meng Wang, Moshe B. Hoshen, Karen Ologoudou, Usha Ramakrishnan, Ruben Grajeda, Manuel Ramirez-Zea, and Reynaldo Martorell. “Comparison of linear growth patterns in the first three years of life across two generations in Guatemala..” Pediatrics 113, no. 3 Pt 1 (March 2004): e270–75. https://doi.org/10.1542/peds.113.3.e270.
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  - Li, Haojie, Ann M. DiGirolamo, Huiman X. Barnhart, Aryeh D. Stein, and Reynaldo Martorell. “Relative importance of birth size and postnatal growth for women's educational achievement..” Early Hum Dev 76, no. 1 (January 2004): 1–16.
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  - Stein, A. D., H. X. Barnhart, M. Wang, M. B. Hoshen, K. Ologoudou, U. Ramakrishnan, R. Grajeda, M. Ramirez-Zea, and R. Martorell. “Comparison of linear growth patterns in the first three years of life across two generations in Guatemala..” Pediatrics 113, no. 3 Pt 1 (January 1, 2004).
  - Wolf, Steven L., Huimnan X. Barnhart, Nancy G. Kutner, Elizabeth McNeely, Carol Coogler, Tingsen Xu, and Tingsen Atlanta FICSIT Group. “Selected as the best paper in the 1990s: Reducing frailty and falls in older persons: an investigation of tai chi and computerized balance training..” J Am Geriatr Soc 51, no. 12 (December 2003): 1794–1803.
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  - Li, Haojie, Huiman X. Barnhart, Aryeh D. Stein, and Reynaldo Martorell. “Effects of early childhood supplementation on the educational achievement of women..” Pediatrics 112, no. 5 (November 2003): 1156–62. https://doi.org/10.1542/peds.112.5.1156.
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  - Kosinski, Andrzej S., and Huiman X. Barnhart. “A global sensitivity analysis of performance of a medical diagnostic test when verification bias is present..” Stat Med 22, no. 17 (September 15, 2003): 2711–21. https://doi.org/10.1002/sim.1517.
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  - Barnhart, Huiman X., and Andrzej S. Kosinski. “Evaluating medical diagnostic tests at the subunit level in the presence of verification bias..” Stat Med 22, no. 13 (July 15, 2003): 2161–76. https://doi.org/10.1002/sim.1436.
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  - Berkowitz, Zahava, Huiman X. Barnhart, and Wendy E. Kaye. “Factors associated with severity of injury resulting from acute releases of hazardous substances in the manufacturing industry..” J Occup Environ Med 45, no. 7 (July 2003): 734–42. https://doi.org/10.1097/01.jom.0000079084.95532.7b.
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  - Dana Flanders, W., H. X. Barnhart, and A. S. Kosinski. “An estimated score method for missing and auxiliary covariates in two stage studies.” Journal of Statistical Planning and Inference 115, no. 1 (July 1, 2003): 145–70. https://doi.org/10.1016/S0378-3758(02)00149-0.
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  - Stein, Aryeh D., Huiman X. Barnhart, Morgen Hickey, Usha Ramakrishnan, Dirk G. Schroeder, and Reynaldo Martorell. “Prospective study of protein-energy supplementation early in life and of growth in the subsequent generation in Guatemala..” Am J Clin Nutr 78, no. 1 (July 2003): 162–67. https://doi.org/10.1093/ajcn/78.1.162.
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  - Li, Haojie, Aryeh D. Stein, Huiman X. Barnhart, Usha Ramakrishnan, and Reynaldo Martorell. “Associations between prenatal and postnatal growth and adult body size and composition..” Am J Clin Nutr 77, no. 6 (June 2003): 1498–1505. https://doi.org/10.1093/ajcn/77.6.1498.
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  - Vitek, Jerrold L., Roy A. E. Bakay, Alan Freeman, Marian Evatt, Joanne Green, William McDonald, Michael Haber, et al. “Randomized trial of pallidotomy versus medical therapy for Parkinson's disease..” Ann Neurol 53, no. 5 (May 2003): 558–69. https://doi.org/10.1002/ana.10517.
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  - Kosinski, Andrzej S., and Huiman X. Barnhart. “Accounting for nonignorable verification bias in assessment of diagnostic tests..” Biometrics 59, no. 1 (March 2003): 163–71.
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  - Zhao, Xue-Qiao, Andrzej S. Kosinski, Huiman X. Barnhart, H. R. Superko, and Spencer B. King. “Prediction of native coronary artery disease progression following PTCA or CABG in the Emory Angioplasty Versus Surgery Trial..” Med Sci Monit 9, no. 2 (February 2003): CR48–54.
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  - Allen, Andrew S., and Huiman X. Barnhart. “Joint models for toxicology studies with dose-dependent number of implantations..” Risk Anal 22, no. 6 (December 2002): 1165–73.
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  - Barnhart, Huiman X., Michael Haber, and Jingli Song. “Overall concordance correlation coefficient for evaluating agreement among multiple observers..” Biometrics 58, no. 4 (December 2002): 1020–27.
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  - Barnhart, Huiman X., and John M. Williamson. “Weighted least-squares approach for comparing correlated kappa..” Biometrics 58, no. 4 (December 2002): 1012–19.
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  - Green, J., W. M. McDonald, J. L. Vitek, M. Haber, H. Barnhart, R. A. E. Bakay, M. Evatt, et al. “Neuropsychological and psychiatric sequelae of pallidotomy for PD: clinical trial findings..” Neurology 58, no. 6 (March 26, 2002): 858–65. https://doi.org/10.1212/wnl.58.6.858.
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  - Barnhart, H. X., and J. M. Williamson. “Modeling concordance correlation via GEE to evaluate reproducibility..” Biometrics 57, no. 3 (September 2001): 931–40.
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  - Green, J., and H. Barnhart. “The impact of lesion laterality on neuropsychological change following posterior pallidotomy: A review of current findings.” Brain and Cognition 42, no. 3 (2000): 379–98. https://doi.org/10.1006/brcg.1999.1111.
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  - Ramakrishnan, U., H. Barnhart, D. G. Schroeder, A. D. Stein, and R. Martorell. “Early childhood nutrition, education and fertility milestones in Guatemala..” J Nutr 129, no. 12 (December 1999): 2196–2202. https://doi.org/10.1093/jn/129.12.2196.
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  - Stiger, T. R., H. X. Barnhart, and J. M. Williamson. “Testing proportionality in the proportional odds model fitted with GEE..” Stat Med 18, no. 11 (June 15, 1999): 1419–33.
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  - Barnhart, H. X., A. S. Kosinski, and A. R. Sampson. “A regression model for multivariate random length data..” Stat Med 18, no. 2 (January 30, 1999): 199–211.
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  - Kutner, N. G., E. F. Mistretta, H. X. Barnhart, and B. F. Belodoff. “Family members' perceptions of quality of life change in dementia SCU residents.” Journal of Applied Gerontology 18, no. 4 (January 1, 1999): 423–39. https://doi.org/10.1177/073346489901800402.
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  - Zhao, X. Q., A. S. Kosinski, R. Malinow, H. X. Barnhart, J. W. Davis, B. G. Brown, and S. B. King. “Association of plasma homocyst(e)ine levels and atherogenic risk factors with native coronary new lesion formation and graft disease after PTCA or CABG in EAST.” Circulation 98, no. 17 (October 27, 1998): 439–439.
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  - Barnhart, H. X., and J. M. Williamson. “Goodness-of-fit tests for GEE modeling with binary responses..” Biometrics 54, no. 2 (June 1998): 720–29.
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  - Zhao, X. “Effect of Plasma Homocyst(e)ine Levels on Adverse Cardiovascular Outcomes After PTCA or CABG in EAST.” Journal of the American College of Cardiology 31, no. 2 (February 1998): 89A-89A. https://doi.org/10.1016/s0735-1097(97)84095-8.
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  - Barnhart, H. X. “A probit model for multivariate random length ordinal data.” Communications in Statistics Theory and Methods 27, no. 7 (January 1, 1998): 1693–1713. https://doi.org/10.1080/03610929808832185.
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  - Stiger, T. R., A. S. Kosinski, H. X. Barnhart, and D. G. Kleinbaum. “ANOVA for repeated ordinal data with small sample size? A comparison of ANOVA, MANOVA, WLS and GEE methods by simulation.” Communications in Statistics Part B: Simulation and Computation 27, no. 2 (January 1, 1998): 357–75. https://doi.org/10.1080/03610919808813485.
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  - Albert, P. S., D. A. Follmann, and H. X. Barnhart. “A generalized estimating equation approach for modeling random length binary vector data..” Biometrics 53, no. 3 (September 1997): 1116–24.
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  - Kutner, N. G., H. Barnhart, S. L. Wolf, E. McNeely, and T. Xu. “Self-report benefits of Tai Chi practice by older adults..” J Gerontol B Psychol Sci Soc Sci 52, no. 5 (September 1997): P242–46. https://doi.org/10.1093/geronb/52b.5.p242.
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  - King, S. B., H. X. Barnhart, A. S. Kosinski, W. S. Weintraub, N. J. Lembo, J. Y. Petersen, J. S. Douglas, et al. “Angioplasty or surgery for multivessel coronary artery disease: comparison of eligible registry and randomized patients in the EAST trial and influence of treatment selection on outcomes. Emory Angioplasty versus Surgery Trial Investigators..” Am J Cardiol 79, no. 11 (June 1, 1997): 1453–59. https://doi.org/10.1016/s0002-9149(97)00170-7.
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  - Wolf, S. L., H. X. Barnhart, G. L. Ellison, and C. E. Coogler. “The effect of Tai Chi Quan and computerized balance training on postural stability in older subjects.” Physical Therapy 77, no. 4 (May 6, 1997): 371–84.
  - Wolf, S. L., H. X. Barnhart, G. L. Ellison, and C. E. Coogler. “The effect of Tai Chi Quan and computerized balance training on postural stability in older subjects. Atlanta FICSIT Group. Frailty and Injuries: Cooperative Studies on Intervention Techniques..” Phys Ther 77, no. 4 (April 1997): 371–81. https://doi.org/10.1093/ptj/77.4.371.
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  - Zhao, X. Q., B. G. Brown, D. K. Stewart, L. A. Hillger, H. X. Barnhart, A. S. Kosinski, W. S. Weintraub, and S. B. King. “Effectiveness of revascularization in the Emory angioplasty versus surgery trial. A randomized comparison of coronary angioplasty with bypass surgery..” Circulation 93, no. 11 (June 1, 1996): 1954–62. https://doi.org/10.1161/01.cir.93.11.1954.
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  - Barnhart, H. X., M. B. Caldwell, P. Thomas, L. Mascola, I. Ortiz, H. W. Hsu, J. Schulte, R. Parrott, Y. Maldonado, and R. Byers. “Natural history of human immunodeficiency virus disease in perinatally infected children: an analysis from the Pediatric Spectrum of Disease Project..” Pediatrics 97, no. 5 (May 1996): 710–16.
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  - Wolf, S. L., H. X. Barnhart, N. G. Kutner, E. McNeely, C. Coogler, and T. Xu. “Reducing frailty and falls in older persons: an investigation of Tai Chi and computerized balance training. Atlanta FICSIT Group. Frailty and Injuries: Cooperative Studies of Intervention Techniques..” J Am Geriatr Soc 44, no. 5 (May 1996): 489–97. https://doi.org/10.1111/j.1532-5415.1996.tb01432.x.
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  - KOSINSKI, A. S., H. X. BARNHART, W. S. WEINTRAUB, R. A. GUYTON, and S. P. KING. “5-YEAR OUTCOME AFTER CORONARY SURGERY OR CORONARY ANGIOPLASTY - RESULTS FROM THE EMORY ANGIOPLASTY VS SURGERY TRIAL (EAST).” Circulation 92, no. 8 (October 15, 1995): 2594–2594.
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  - King, S. B., N. J. Lembo, W. S. Weintraub, A. S. Kosinski, H. X. Barnhart, and M. H. Kutner. “Emory Angioplasty Versus Surgery Trial (EAST): design, recruitment, and baseline description of patients..” Am J Cardiol 75, no. 9 (March 23, 1995): 42C-59C.
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  - Barnhart, H. X., and A. R. Sampson. “Multiple population models for multivariate random length data--with applications in clinical trials..” Biometrics 51, no. 1 (March 1995): 195–204.
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  - King, S. B., N. J. Lembo, W. S. Weintraub, A. S. Kosinski, H. X. Barnhart, M. H. Kutner, N. P. Alazraki, R. A. Guyton, and X. Q. Zhao. “A randomized trial comparing coronary angioplasty with coronary bypass surgery. Emory Angioplasty versus Surgery Trial (EAST).” N Engl J Med 331, no. 16 (October 20, 1994): 1044–50. https://doi.org/10.1056/NEJM199410203311602.
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  - Barnhart, H. X., and A. R. Sampson. “Overview of multinomial models for ordinal data.” Communications in Statistics Theory and Methods 23, no. 12 (January 1, 1994): 3395–3416. https://doi.org/10.1080/03610929408831454.
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  - Barnhart, H. X. “Models for multivariate random length data with applications in clinical trials.” Drug Information Journal 27, no. 4 (1993): 1147–57.
- Conference Papers
  - Crowley, Anna Lisa, Eric Yow, Dawn Rabineau, Casey Norris, Jennifer White, Melissa A. Daubert, Eric J. Velazquez, et al. “The Impact of a Rigorous Quality Program on 3D Echocardiography Data Quality in an International Multisite Randomized Trial..” In Jacc Cardiovasc Imaging, 11:1918–20, 2018. https://doi.org/10.1016/j.jcmg.2018.05.024.
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  - Ahmad, Jawad, K Rajender Reddy, Hans L. Tillmann, Naga P. Chalasani, Paul H. Hayashi, Robert J. Fontana, Victor J. Navarro, et al. “Testing for Hepatitis C Virus RNA is Recommended in Patients with Suspected Drug Induced Liver Injury (DILI).” In Hepatology, 66:5A-6A. WILEY, 2017.
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  - DiPaola, Frank, Jean Molleston, Huiman X. Barnhart, Naga P. Chalasani, Sherry Gu, David E. Kleiner, Jay H. Hoofnagle, and Robert J. Fontana. “Minocycline and anti-epileptics are the leading causes of DILI in Children.” In Hepatology, 66:4A-4A. WILEY, 2017.
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  - Urban, Thomas Jacob, Paola Nicoletti, Naga Chalasani, José Serrano, Andrew Stolz, Ann K. Daly, Guruprasad P. Aithal, et al. “Minocycline hepatotoxicity: Clinical characterization and identification of HLA-B∗35:02 as a risk factor..” In J Hepatol, 67:137–44, 2017. https://doi.org/10.1016/j.jhep.2017.03.010.
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  - Ahmad, Jawad, Simona Rossi, Shuchi K. Rodgers, Robert J. Fontana, Naga P. Chalasani, Andrew Stolz, Paul H. Hayashi, Huiman X. Barnhart, David E. Kleiner, and Einar Bjornsson. “Drug Induced Liver Injury Associated with Sclerosing Cholangitis Like Changes on Magnetic Resonance Cholangiography Imaging.” In Hepatology, 64:65A-65A. WILEY, 2016.
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  - Chalasani, Naga P., Marwan Ghabril, Robert J. Fontana, Huiman X. Barnhart, Paul H. Hayashi, Jawad Ahmad, Andrew Stolz, Victor J. Navarro, and Jay H. Hoofnagle. “Idiosyncratic drug induced liver injury in African Americans: Causes, Clinical Features and Outcomes.” In Hepatology, 64:64A-64A. WILEY, 2016.
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  - Tillmann, Hans L., Huiman X. Barnhart, Jose Serrano, and Don C. Rockey. “A Novel Computerized Drug Induced Liver Injury Causality Assessment Tool (DILI-CAT).” In Hepatology, 64:320A-321A. WILEY, 2016.
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  - Aithal, Guruprasad P., Paola Nicoletti, Einar Bjornsson, M. I. Lucena, Raul J. Andrade, Jane Grove, C. Stephens, et al. “HLA-A*33:01 is strongly associated with drug-induced liver injury (DILI) due to terbinafine and several other unrelated compounds.” In Hepatology, 62:325A-326A. WILEY-BLACKWELL, 2015.
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  - Hayashi, Paul H., Don C. Rockey, Robert J. Fontana, Hans L. Tillmann, Neil Kaplowitz, Huiman X. Barnhart, Jiezhun Gu, et al. “Death and Liver Transplantations Occurring Within Two Years of Drug-Induced Liver Injury.” In Hepatology, 62:1145A-1146A. WILEY-BLACKWELL, 2015.
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  - Navarro, Victor J., Manisha Verma, Huiman X. Barnhart, Marwan Ghabril, Robert J. Fontana, Joseph A. Odin, Andrew Stolz, Maricruz Vega, and Paul B. Watkins. “The Epidemiology of Suspected Drug Induced Liver Injury in the US: The Delaware Liver Injury Study.” In Hepatology, 62:1150A-1150A. WILEY-BLACKWELL, 2015.
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  - Stolz, Andrew, Victor J. Navarro, Paul H. Hayashi, Naga P. Chalasani, Robert J. Fontana, Herbert L. Bonkovsky, Sunil Hwang, Jay H. Hoofnagle, David E. Kleiner, and Huiman X. Barnhart. “Severe and prolonged jaundice associated with body building supplements (BBS): review of 44 cases from the Drug-Induced Liver Injury Network (DILIN).” In Hepatology, 62:1146A-1146A. WILEY-BLACKWELL, 2015.
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  - Urban, Thomas J., Paola Nicoletti, Robert J. Fontana, Andrew Stolz, Ann K. Daly, Guruprasad P. Aithal, M. I. Lucena, Huiman X. Barnhart, Paul Watkins, and Naga P. Chalasani. “Genome-wide investigation identifies common SNPs on Chr9p22.2 as risk factors for liver injury due to sulfa-methoxazole/trimethoprim.” In Hepatology, 62:1151A-1151A. WILEY-BLACKWELL, 2015.
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  - Khouri, Michel Georges, Bonnie Ky, Gary Dunn, Theodore Plappert, Virginia Englefield, Eric Yow, Huiman X. Barnhart, Martin St John Sutton, and Pamela Douglas. “ECHOCARDIOGRAPHY CORE LAB REPRODUCIBILITY OF CARDIAC SAFETY ASSESSMENTS IN CARDIO-ONCOLOGY.” In Journal of the American College of Cardiology, 65:A1323–A1323. Elsevier BV, 2015. https://doi.org/10.1016/s0735-1097(15)61323-7.
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  - Rockey, Don C. “To transfuse or not to transfuse in upper gastrointestinal hemorrhage? That is the question..” In Hepatology, 60:422–24, 2014. https://doi.org/10.1002/hep.26994.
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  - Fontana, Robert J., Paul H. Hayashi, Rajender Reddy, David E. Kleiner, Thomas Phillips, Huiman X. Barnhart, Jayant A. Talwalkar, et al. “Cholestatic Drug reactions are more likely to cause persistent liver injury and impaired Quality of Life during prolonged follow-up: Results from the DILIN Prospective study.” In Hepatology, 60:719A-720A. WILEY-BLACKWELL, 2014.
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  - Navarro, Victor J., Huiman X. Barnhart, Herbert L. Bonkovsky, Timothy J. Davern, Robert J. Fontana, Lafaine Grant, Jay H. Hoofnagle, et al. “The Rising Burden of Herbal and Dietary Supplement Induced Hepatotoxicity in the U. S. A.” In Hepatology, 58:264A-264A. WILEY-BLACKWELL, 2013.
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  - Fontana, Robert J., Jiezhun Gu, Huiman X. Barnhart, Paul H. Hayashi, K Rajender Reddy, Jayant Talwalkar, Naga P. Chalasani, et al. “Subject race and liver biochemical profile are strongly associated with clinical outcomes and chronic liver injury: Results from the DILIN Prospective study.” In Hepatology, 56:601A-601A. WILEY-BLACKWELL, 2012.
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  - Foureau, David M., Tracy L. Walling, David E. Kleiner, William A. Ahrens, W Carl Jacobs, Lain H. McKillop, Huiman X. Barnhart, Jose Serrano, and Herbert L. Bonkovsky. “Profiles of Leukocytes Infiltrating Livers of Subjects with Drug-Induced Liver Injury (DILI).” In Hepatology, 56:596A-597A. WILEY-BLACKWELL, 2012.
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  - Hayashi, Paul H., Huiman X. Barnhart, Robert J. Fontana, Naga P. Chalasani, Timothy J. Davern, Jayant Talwalkar, K Rajender Reddy, Andrew Stolz, Jay H. Hoofnagle, and Don C. Rockey. “Reliability of the Drug Induced Liver Injury Network (DILIN) Expert Opinion Process in the Diagnosis of DILI.” In Hepatology, 56:596A-596A. WILEY-BLACKWELL, 2012.
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  - Urban, Thomas J., Kevin Shianna, Huiman X. Barnhart, Naga P. Chalasani, Robert J. Fontana, Jose Serrano, Andrew Stolz, David B. Goldstein, and Paul B. Watkins. “Whole-exome sequencing identifies rare genetic variants that may contribute to isoniazid (INH)-induced liver injury.” In Hepatology, 56:593A-594A. WILEY-BLACKWELL, 2012.
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  - Navarro, V. J., H. X. Barnhart, H. L. Bonkovsky, K. R. Reddy, L. Seeff, J. Serrano, J. A. Talwalkar, M. Vega, and R. Vuppalanchi. “1364 DIAGNOSING HEPATOTOXICITY ATTRIBUTABLE TO HERBAL & DIETARY SUPPLEMENTS (HDS): TEST-RETEST RELIABILITY OF A NOVEL CAUSALITY ASSESSMENT TOOL.” In Journal of Hepatology, 56:S536–S536. Elsevier BV, 2012. https://doi.org/10.1016/s0168-8278(12)61375-0.
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  - Navarro, Victor J., Huiman X. Barnhart, Herbert L. Bonkovsky, and Sun-il Hwang. “GREEN TEA EXTRACT CONTAINING HERBAL & DIETARY SUPPLEMENTS ARE FREQUENTLY MISLABELED IN THE USA: THE US DRUG-INDUCED LIVER INJURY NETWORK (DILIN) EXPERIENCE.” In Hepatology, 54:526A-527A. WILEY-BLACKWELL, 2011.
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  - Chen, B., S. Richard, H. Barnhart, J. Colsher, M. Amurao, and E. Samei. “Quantitative CT: Technique dependency of volume assessment for pulmonary nodules.” In Progress in Biomedical Optics and Imaging Proceedings of Spie, Vol. 7622, 2010. https://doi.org/10.1117/12.845493.
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  - Cataldo, N. A., R. S. Legro, E. R. Myers, and H. X. Barnhart. “Co-treatment with metformin XR does not reduce the threshold dose of clomiphene to induce ovulation in polycystic ovary syndrome: results from the pregnancy in polycystic ovary syndrome (PPCOS) study.” In Fertility and Sterility, 88:S73–74. Elsevier BV, 2007. https://doi.org/10.1016/j.fertnstert.2007.07.246.
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  - Legro, R. S., E. R. Myers, H. X. Barnhart, S. A. Carson, M. P. Diamond, B. A. Carr, W. D. Schlaff, et al. “Pregnancy in polycystic ovary syndrome (PPCOS) baseline characteristics: Effect of race and ethnicity on the PCOS phenotype..” In Journal of the Society for Gynecologic Investigation, 13:268A-269A. ELSEVIER SCIENCE INC, 2006.
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  - Legro, R. S., E. R. Myers, H. X. Barnhart, S. A. Carson, M. P. Diamond, B. A. Carr, W. D. Schlaff, et al. “Pregnancy in polycystic ovary syndrome (PPCOS): Study design and baseline characteristics of the randomized cohort..” In Journal of the Society for Gynecologic Investigation, 13:269A-269A. ELSEVIER SCIENCE INC, 2006.
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  - Kosinski, A. S., H. X. Barnhart, and W. S. Weintraub. “"Ignorance region" of sensitivity and specificity of a diagnostic test when not all patients are verified with a gold standard.” In American Heart Journal, 144:884–884. MOSBY, INC, 2002.
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