Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • M.B.B.Ch., University of Witwatersrand (South Africa) 1968
• 

  Previous Appointments & Affiliations

  • Associate Professor of Community and Family Medicine, Family Medicine and Community Health, Clinical Science Departments 1994 - 2011
  • Associate Professor of Medicine, Neurology, Clinical Science Departments 1985 - 2010
• Research
• 

  Selected Grants

  • Aging And Cognitive After Cardiac Surgery awarded by National Institutes of Health 1996 - 1999
  • Aging And Cognition After Cardiac Surgery awarded by National Institutes of Health 1994 - 1999
  • Aging And Cognition After Cardiac Surgery awarded by National Institutes of Health 1991 - 1999
  • Antiarrhythmic Mechanisms In Ischemic Myocardium awarded by National Institutes of Health 1988 - 1991
  • Antiarrhythmic Mechanisms In Ischemic Myocardium awarded by National Institutes of Health 1985 - 1990
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Hurwitz, Barrie J. “Analysis of current multiple sclerosis registries.” Neurology 76, no. 1 Suppl 1 (January 4, 2011): S7-13. https://doi.org/10.1212/WNL.0b013e31820502f6.
       Full Text  Link to Item
    • Hurwitz, Barrie J. “Registry studies of long-term multiple sclerosis outcomes: description of key registries.” Neurology 76, no. 1 Suppl 1 (January 4, 2011): S3–6. https://doi.org/10.1212/WNL.0b013e3182050225.
       Full Text  Link to Item
    • Lövblad, K. -. O., N. Anzalone, A. Dörfler, M. Essig, B. Hurwitz, L. Kappos, S. -. K. Lee, and M. Filippi. “MR imaging in multiple sclerosis: review and recommendations for current practice.” Ajnr Am J Neuroradiol 31, no. 6 (June 2010): 983–89. https://doi.org/10.3174/ajnr.A1906.
       Full Text  Link to Item
    • Hurwitz, Barrie J. “The diagnosis of multiple sclerosis and the clinical subtypes.” Ann Indian Acad Neurol 12, no. 4 (October 2009): 226–30. https://doi.org/10.4103/0972-2327.58276.
       Full Text  Link to Item
    • Coyle, P., B. Arnason, B. Hurwitz, and F. Lublin. “Optimizing outcomes in multiple sclerosis - A consensus initiative.” Multiple Sclerosis 15, no. SUPPL. 2 (April 27, 2009). https://doi.org/10.1177/1352458508101134.
       Full Text
    • Hurwitz, B. J. “Important sources of variability in clinical studies of neutralizing antibodies against interferon beta.” J Neurol Sci 272, no. 1–2 (September 15, 2008): 8–19. https://doi.org/10.1016/j.jns.2008.05.004.
       Full Text  Link to Item
    • Hurwitz, Barrie J., Douglas Jeffery, Barry Arnason, Kim Bigley, Patricia Coyle, Douglas Goodin, Samer Kaba, et al. “Tolerability and safety profile of 12- to 28-week treatment with interferon beta-1b 250 and 500 microg QOD in patients with relapsing-remitting multiple sclerosis: a multicenter, randomized, double-blind, parallel-group pilot study.” Clin Ther 30, no. 6 (June 2008): 1102–12. https://doi.org/10.1016/j.clinthera.2008.06.013.
       Full Text  Link to Item
    • Goodin, D. S., B. Hurwitz, and A. Noronha. “Neutralizing antibodies to interferon β-1b are not associated with disease worsening in multiple sclerosis.” Journal of International Medical Research 35, no. 2 (January 1, 2007): 173–87. https://doi.org/10.1177/147323000703500202.
       Full Text
    • Mikol, D., M. Lopez-Bresnahan, S. Taraskiewicz, P. Chang, J. Rangnow, and J. Rebiject Study Group. “A randomized, multicentre, open-label, parallel-group trial of the tolerability of interferon beta-1a (Rebif) administered by autoinjection or manual injection in relapsing-remitting multiple sclerosis.” Mult Scler 11, no. 5 (October 2005): 585–91. https://doi.org/10.1191/1352458505ms1197oa.
       Full Text  Link to Item
    • Hurwitz, Barrie. “Editorial: Licensing and Use of New Therapies in MS: Where Are We Going?” Int Ms J 12, no. 2 (August 2005): 39–41.
       Link to Item
    • Sandberg-Wollheim, M., C. Bever, J. Carter, M. Färkkilä, B. Hurwitz, Y. Lapierre, P. Chang, G. S. Francis, and G. S. EVIDENCE Study Group. “Comparative tolerance of IFN beta-1a regimens in patients with relapsing multiple sclerosis. The EVIDENCE study.” J Neurol 252, no. 1 (January 2005): 8–13. https://doi.org/10.1007/s00415-005-0589-2.
       Full Text  Link to Item
    • Croughwell, N. D., M. F. Newman, J. A. Blumenthal, W. D. White, J. B. Lewis, P. E. Frasco, L. R. Smith, E. A. Thyrum, B. J. Hurwitz, and B. J. Leone. “Jugular bulb saturation and cognitive dysfunction after cardiopulmonary bypass.” Ann Thorac Surg 58, no. 6 (December 1994): 1702–8. https://doi.org/10.1016/0003-4975(94)91666-7.
       Full Text  Link to Item
    • NEWMAN, M. F., N. D. CROUGHWELL, J. A. BLUMENTHAL, W. D. WHITE, J. B. LEWIS, L. R. SMITH, P. FRASCO, et al. “EFFECT OF AGING ON CEREBRAL AUTOREGULATION DURING CARDIOPULMONARY BYPASS - ASSOCIATION WITH POSTOPERATIVE COGNITIVE DYSFUNCTION.” Circulation 90, no. 5 (November 1, 1994): 243–49.
       Link to Item
    • Newman, M. F., N. D. Croughwell, J. A. Blumenthal, W. D. White, J. B. Lewis, L. R. Smith, P. Frasco, E. A. Towner, R. M. Schell, and B. J. Hurwitz. “Effect of aging on cerebral autoregulation during cardiopulmonary bypass. Association with postoperative cognitive dysfunction.” Circulation 90, no. 5 Pt 2 (November 1994): II243–49.
       Link to Item
    • Newman, M. F., N. D. Croughwell, J. A. Blumenthal, W. D. White, J. B. Lewis, L. R. Smith, P. Frasco, et al. “Effect of aging on cerebral autoregulation during cardiopulmonary bypass: Association with postoperative cognitive dysfunction.” Circulation 90, no. 5 II (November 1, 1994).
    • Cavazos, J. E., J. B. Caress, V. R. Chilukuri, T. Devlin, L. Gray, and B. J. Hurwitz. “Sumatriptan-induced stroke in sagittal sinus thrombosis.” Lancet 343, no. 8905 (April 30, 1994): 1105–6. https://doi.org/10.1016/s0140-6736(94)90220-8.
       Full Text  Link to Item
    • Ondo, W. G., and B. J. Hurwitz. “Tardive dyskinesia and pseudo-parkinsonism. In a nursing home patient who itched.” N C Med J 54, no. 11 (November 1993): 605–7.
       Link to Item
    • Ehrlich, G. D., J. B. Glaser, V. Bryz-Gornia, J. Maese, T. A. Waldmann, B. J. Poiesz, and S. J. Greenberg. “Multiple sclerosis, retroviruses, and PCR. The HTLV-MS Working Group.” Neurology 41, no. 3 (March 1991): 335–43. https://doi.org/10.1212/wnl.41.3.335.
       Full Text  Link to Item
    • Morgenlander, J. C., B. J. Hurwitz, and E. W. Massey. “Capsaicin for the treatment of pain in Guillain-Barré syndrome.” Ann Neurol 28, no. 2 (August 1990): 199. https://doi.org/10.1002/ana.410280222.
       Full Text  Link to Item
    • “Efficacy and toxicity of cyclosporine in chronic progressive multiple sclerosis: a randomized, double-blinded, placebo-controlled clinical trial. The Multiple Sclerosis Study Group.” Ann Neurol 27, no. 6 (June 1990): 591–605. https://doi.org/10.1002/ana.410270603.
       Full Text  Link to Item
    • Greenberg, S. J., G. D. Ehrlich, M. A. Abbott, B. J. Hurwitz, T. A. Waldmann, and B. J. Poiesz. “Detection of sequences homologous to human retroviral DNA in multiple sclerosis by gene amplification.” Proc Natl Acad Sci U S A 86, no. 8 (April 1989): 2878–82. https://doi.org/10.1073/pnas.86.8.2878.
       Full Text  Link to Item
    • Greenberg, S. J., L. Marcon, B. J. Hurwitz, T. A. Waldmann, and D. L. Nelson. “Elevated levels of soluble interleukin-2 receptors in multiple sclerosis.” N Engl J Med 319, no. 15 (October 13, 1988): 1019–20. https://doi.org/10.1056/NEJM198810133191517.
       Full Text  Link to Item
    • Nelson, L. M., G. M. Franklin, and M. C. Jones. “Risk of multiple sclerosis exacerbation during pregnancy and breast-feeding.” Jama 259, no. 23 (June 17, 1988): 3441–43.
       Link to Item
    • Drayer, B. P., P. Burger, B. Hurwitz, D. Dawson, J. Cain, J. Leong, R. Herfkens, and G. A. Johnson. “Magnetic resonance imaging in multiple sclerosis: decreased signal in thalamus and putamen.” Ann Neurol 22, no. 4 (October 1987): 546–50. https://doi.org/10.1002/ana.410220418.
       Full Text  Link to Item
    • Heyman, A., W. E. Wilkinson, B. J. Hurwitz, M. J. Helms, C. S. Haynes, C. M. Utley, and L. P. Gwyther. “Early-onset Alzheimer's disease: clinical predictors of institutionalization and death.” Neurology 37, no. 6 (June 1987): 980–84. https://doi.org/10.1212/wnl.37.6.980.
       Full Text  Link to Item
    • Hurwitz, B. J., A. Heyman, P. C. Burger, and B. P. Drayer. “Subcortical arteriosclerotic encephalopathy (Binswanger's disease). Report of a case simulating psychiatric disease and normal pressure hydrocephalus.” N C Med J 48, no. 4 (April 1987): 182–86.
       Link to Item
    • Drayer, B., P. Burger, B. Hurwitz, D. Dawson, and J. Cain. “Reduced signal intensity on MR images of thalamus and putamen in multiple sclerosis: Increased iron content?” American Journal of Roentgenology 149, no. 2 (January 1, 1987): 357–63. https://doi.org/10.2214/ajr.149.2.357.
       Full Text
    • Drayer, B., P. Burger, and B. Hurwitz. “Reduced signal intensity on MR images of thalamus and putamen in multiple sclerosis: Increased iron content?” American Journal of Neuroradiology 8, no. 3 (January 1, 1987): 413–19.
    • Belkin, R. N., B. J. Hurwitz, and J. Kisslo. “Atrial septal aneurysm: association with cerebrovascular and peripheral embolic events.” Stroke 18, no. 5 (1987): 856–62. https://doi.org/10.1161/01.str.18.5.856.
       Full Text  Link to Item
    • Hurwitz, B. J., A. Heyman, W. E. Wilkinson, C. S. Haynes, and C. M. Utley. “Comparison of amaurosis fugax and transient cerebral ischemia: a prospective clinical and arteriographic study.” Ann Neurol 18, no. 6 (December 1985): 698–704. https://doi.org/10.1002/ana.410180612.
       Full Text  Link to Item
    • Heyman, A., W. E. Wilkinson, B. J. Hurwitz, C. S. Haynes, C. M. Utley, R. A. Rosati, J. G. Burch, and T. B. Gore. “Risk of ischemic heart disease in patients with TIA.” Neurology 34, no. 5 (May 1984): 626–30. https://doi.org/10.1212/wnl.34.5.626.
       Full Text  Link to Item
    • Hodson, A. K., B. J. Hurwitz, and R. Albrecht. “Dysautonomia in Guillain-Barré syndrome with dorsal root ganglioneuropathy, wallerian degeneration, and fatal myocarditis.” Ann Neurol 15, no. 1 (January 1984): 88–95. https://doi.org/10.1002/ana.410150116.
       Full Text  Link to Item
    • Heyman, A., W. E. Wilkinson, B. J. Hurwitz, D. Schmechel, A. H. Sigmon, T. Weinberg, M. J. Helms, and M. Swift. “Alzheimer's disease: genetic aspects and associated clinical disorders.” Ann Neurol 14, no. 5 (November 1983): 507–15. https://doi.org/10.1002/ana.410140503.
       Full Text  Link to Item
    • Kinney, H. C., P. C. Burger, B. J. Hurwitz, J. C. Hijmans, and J. P. Grant. “Degeneration of the central nervous system associated with celiac disease.” J Neurol Sci 53, no. 1 (January 1982): 9–22. https://doi.org/10.1016/0022-510x(82)90076-4.
       Full Text  Link to Item
    • Kaufman, M. D., L. C. Hopkins, and B. J. Hurwitz. “Progressive sensory neuropathy in patients without carcinoma: a disorder with distinctive clinical and electrophysiological findings.” Ann Neurol 9, no. 3 (March 1981): 237–42. https://doi.org/10.1002/ana.410090306.
       Full Text  Link to Item
    • Rottenberg, D. A., B. J. Hurwitz, and J. B. Posner. “The effect of oral glycerol on intraventricular pressure in man.” Neurology 27, no. 7 (July 1977): 600–608. https://doi.org/10.1212/wnl.27.7.600.
       Full Text  Link to Item
    • Hurwitz, B. J., and J. B. Posner. “Cerebral infarction complicating subclavian vein catheterization .” Ann Neurol 1, no. 3 (March 1977): 253–54. https://doi.org/10.1002/ana.410010310.
       Full Text  Link to Item
    • Hurwitz, B. J., and D. A. Rottenberg. “Letter: Impaired clycerol clearance in obesity.” Lancet 2, no. 7941 (November 8, 1975): 933. https://doi.org/10.1016/s0140-6736(75)92179-0.
       Full Text  Link to Item
    • Hurwitz, B. J., and D. A. Rottenberg. “Letter: Glycerol, cerebral oedema, and diabetes.” Lancet 2, no. 7930 (August 23, 1975): 369. https://doi.org/10.1016/s0140-6736(75)92815-9.
       Full Text  Link to Item

  • Other Articles

    • Harshaw-Ellis, Karol. “Letter to the Editor,” n.d. https://doi.org/10.1016/j.nurpra.2021.04.006.
       Full Text  Open Access Copy

  • Conference Papers

    • Goodin, D. S., A. Noronha, and B. J. Hurwitz. “Neutralising antibodies to interferon-beta-1b have no impact on clinical response in multiple sclerosis.” In Multiple Sclerosis, 12:S205–S205. SAGE PUBLICATIONS LTD, 2006.
       Link to Item
    • Kirzinger, S. S., B. J. Hurwitz, B. G. Arnason, G. K. Bigley, P. K. Coyle, D. S. Goodin, D. R. Jeffery, et al. “First phase of the BEYOND programme: 1-year interim analysis of an open-label, extension study comparing 500 mcg and 250 mcg interferon beta-1b.” In Journal of Neurology, 252:126–27. DR DIETRICH STEINKOPFF VERLAG, 2005.
       Link to Item
    • BELKIN, R. N., B. J. HURWITZ, and J. KISSLO. “ATRIAL SEPTAL ANEURYSM - ASSOCIATION WITH CEREBROVASCULAR AND PERIPHERAL EMBOLIC EVENTS.” In Circulation, 74:178–178. AMER HEART ASSOC, 1986.
       Link to Item
    • HEYMAN, A., W. E. WILKINSON, B. J. HURWITZ, and D. E. SCHMECHEL. “GENETIC-STUDIES OF ALZHEIMERS-DISEASE.” In Annals of Neurology, 14:150–51. LIPPINCOTT-RAVEN PUBL, 1983.
       Link to Item
    • HEYMAN, A., T. GORE, W. E. WILKINSON, B. J. HURWITZ, J. G. BURCH, C. S. HAYNES, and C. M. UTLEY. “TIA WITH BENIGN OUTCOME.” In Stroke, 13:112–112. AMER HEART ASSOC, 1982.
       Link to Item

Some information on this profile has been compiled automatically from Duke databases and external sources. (Our About page explains how this works.) If you see a problem with the information, please write to Scholars@Duke and let us know. We will reply promptly.