Scholars@Duke
Isaac David Smith

Isaac David Smith

Assistant Professor of Medicine
Medicine, Rheumatology and Immunology
isaac.smith063@duke.edu
40 Duke Medicine Circle, Clinic 1J, Durham, NC 27710

Selected Publications

Agreement of Administrative Pharmacy Dispensing With Self-Reported Use of Oral Prednisone in US Veterans With Rheumatoid Arthritis.

Journal Article Arthritis Care Res (Hoboken) · November 2025 OBJECTIVE: Administrative claims are used to evaluate oral glucocorticoid use in rheumatoid arthritis (RA), despite limited evidence to support accuracy. We aimed to evaluate the performance of claims-based algorithms for glucocorticoid use compared to sel ... Full text Link to item Cite

Medication adherence in rheumatoid arthritis: implications for cardiovascular disease risk and strategies to address in U.S. veterans.

Journal Article Expert Rev Pharmacoecon Outcomes Res · April 2025 INTRODUCTION: Rheumatoid arthritis (RA) is a systemic inflammatory disease associated with an increased risk of cardiovascular disease (CVD) and premature mortality. The risk of CVD is closely associated with RA disease activity, and achieving RA remission ... Full text Link to item Cite

Lessons on Telemedicine in Rheumatology: Thinking beyond the Coronavirus Disease 2019 Pandemic.

Journal Article Rheum Dis Clin North Am · February 2025 During the COVID-19 pandemic, telemedicine was rapidly deployed to meet the clinical needs of patients with rheumatic diseases worldwide. Rheumatologists were forced to care for patients with all rheumatic diseases, regardless of disease activity, and limi ... Full text Link to item Cite

Evaluating Factors Associated With Telehealth Appropriateness in Outpatient Rheumatoid Arthritis Encounters Using the Encounter Appropriateness Score for You (EASY).

Journal Article J Rheumatol · August 1, 2024 OBJECTIVE: Telehealth has been proposed as a safe and effective alternative to in-person care for rheumatoid arthritis (RA). The purpose of this study was to evaluate factors associated with telehealth appropriateness in outpatient RA encounters. METHODS: ... Full text Open Access Link to item Cite

Evaluating Provider Perceptions of Telehealth Utility in Outpatient Rheumatology Telehealth Encounters.

Journal Article J Clin Rheumatol · March 1, 2024 OBJECTIVE: This study aims to explore the factors associated with rheumatology providers' perceptions of telehealth utility in real-world telehealth encounters. METHODS: From September 14, 2020 to January 31, 2021, 6 providers at an academic medical center ... Full text Link to item Cite

Encounter Appropriateness Score for You Model: Development and Pilot Implementation of a Predictive Model to Identify Visits Appropriate for Telehealth in Rheumatology.

Journal Article Arthritis Care Res (Hoboken) · January 2024 OBJECTIVE: We aimed to develop a decision-making tool to predict telehealth appropriateness for future rheumatology visits and expand telehealth care access. METHODS: The model was developed using the Encounter Appropriateness Score for You (EASY) and elec ... Full text Link to item Cite

Use of Structured Electronic Health Records Data Elements for the Development of Computable Phenotypes to Identify Potential Adverse Events Associated with Intravenous Immunoglobulin Infusion.

Journal Article Drug Saf · March 2023 INTRODUCTION: Detection of adverse reactions to drugs and biologic agents is an important component of regulatory approval and post-market safety evaluation. Real-world data, including insurance claims and electronic health records data, are increasingly u ... Full text Link to item Cite

Telehealth Made EASY: Understanding Provider Perceptions of Telehealth Appropriateness in Outpatient Rheumatology Encounters.

Journal Article ACR Open Rheumatol · October 2022 OBJECTIVE: The purpose of this study was to evaluate a novel scoring system, the Encounter Appropriateness Score for You (EASY), to assess provider perceptions of telehealth appropriateness in rheumatology encounters. METHODS: The EASY scoring system promp ... Full text Open Access Link to item Cite

Alcohol consumption and the risk of mortality and myocardial infarction in patients with rheumatoid arthritis.

Journal Article Clin Exp Rheumatol · September 2022 OBJECTIVES: Many studies have found that moderate alcohol consumption is associated with lower risks of mortality and myocardial infarction (MI). Our aim was to examine the potential effects of alcohol on all-cause mortality and MI in rheumatoid arthritis ... Full text Link to item Cite

The Relation of Accelerometer-Measured Physical Activity and Serum Uric Acid Using the National Health and Nutrition Survey (NHANES) 2003-2004.

Journal Article Front Sports Act Living · 2021 Objective: Gout is a crystal-induced inflammatory arthritis caused by elevated uric acid. Physical activity has the potential to reduce serum uric acid (SUA), thus improving the disease burden of gout. In this study, we examined the association of objectiv ... Full text Open Access Link to item Cite

Provider Assessment of Telehealth Utility During COVID-19

Conference ARTHRITIS & RHEUMATOLOGY · 2021 Cite

Rheumatology

Chapter · 2020 This new review brings you authoritative, trusted content designed to prepare you for success on licensing, certification, and recertification exams and hone your knowledge of internal medicine. ... Cite

Rheumatology

Chapter · 2019 The flagship volume in the popular Pocket Notebook series, Pocket Medicine, 7th Edition, is a must-have resource for fast answers to diagnostic questions you’ll face on rounds and exams. ... Cite

Recommendations for QTc Monitoring: Rational or Arbitrary?

Journal Article Prim Care Companion CNS Disord · October 4, 2018 Full text Link to item Cite