Glenn Jay Jaffe
Robert Machemer M.D. Distinguished Professor of Ophthalmology
I have an active basic and clinical research program. I have been principal investigator on several funded clinical studies including investigations of an oral ganciclovir prodrug to treat CMV retinitis and a study to determine the safety of a cyclosporine sustained drug delivery implant in the treatment of uveitis. I am principal investigator of an ongoing multicenter trial of a fluocinolone sustained drug delivery implant to treat patients with severe uveitis and a trial of this same implant to treat diabetic macular edema. Recently, I have investigated the use of ultrasonography and optical coherence tomography to diagnose macular edema in a variety of ocular diseases. I have maintained an ongoing basic research program to test the hypothesis that cytokines are important in the development of proliferative vitreoretinopathy, an important intraocular wound healing disorder. Education: I am actively involved in resident and fellow education. I give lectures to residents and fellows on a variety of topics related to uveitis and vitreoretinal diseases and train fellows to perform vitreoretinal surgery. I train post-doctoral students and medical students to conduct clinically relevant research. I serve as a mentor for the Duke third year medical school research program. I have served on a yearly basis as course faculty at many national and international meetings.
Current Appointments & Affiliations
- Robert Machemer M.D. Distinguished Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology 2013
- Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology 1998
- Chief, Division of Retinal Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology 2008
Contact Information
- Box 3802 Med Ctr, Durham, NC 27710
- Duke Eye Center, 2351 Erwin Ro, Durham, NC 27710
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jaffe001@mc.duke.edu
(919) 684-4458
- Background
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Education, Training, & Certifications
- Vitreoretinal Fellowship, The Eye Institute, Medical College of Wisconsin 1987 - 1989
- Residency, University of California San Francisco at Fresno, School of Medicine 1984 - 1987
- M.D., University of California San Francisco, School of Medicine 1983
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Previous Appointments & Affiliations
- Associate Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology 1994 - 1998
- Assistant Professor of Ophthalmology, Ophthalmology, Vitreoretinal Diseases & Surgery, Ophthalmology 1989 - 1994
- Recognition
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In the News
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SEP 8, 2016 Duke Health News
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- Research
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Selected Grants
- A Phase 2 Randomized, Controlled, Double-Masked Trial to Evaluate the Safety and Efficacy of Intravitreal 4D-150 Gene Therapy in Adults with Diabetic Macular Edema (SPECTRA Study) awarded by 4D Molecular Therapeutics 2023 - 2027
- NAC Attack, a phase-3, multicenter, randomized, placebo-controlled trial with retinitis pigmentosa: OCT Reading Center awarded by National Institutes of Health 2022 - 2027
- Genentech-A MULTICENTER, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND TOLERABILITY OF THE RANIBIZUMAB PORT DELIVERY SYSTEM IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION WHO HAVE COMPLETED A GENENTECH SPONSORED STUDY awarded by Genentech, Inc. 2018 - 2026
- Novartis DRC An open-label first-in-human single ascending dose study to explore the safety, tolerability and efficacy of subretinal administration of CPK850 gene therapy in patients with retinitis pigmentosa caused by mutations in the RLBP1 gene awarded by Novartis Pharma AG 2018 - 2026
- A Phase 1/2 Dose-Escalation and Dose-Randomized, Masked Expansion Trial of Intravitreal 4D-150 Gene Therapy in Adults with Neovascular (Wet) Age-Related Macular Degeneration awarded by 4D Molecular Therapeutics 2021 - 2025
- Rate of Progression of PCDH15-Related Retinal Degeneration in Usher Syndrome 1F (RUSH1F) awarded by Jaeb Center For Health Research 2021 - 2025
- Rate of Progression in EYS-Related Retinal Degeneration (PRO-EYS) awarded by Jaeb Center For Health Research 2019 - 2025
- Rate of Progression in USH2A Related Retinal Degeneration (RUSH2A) awarded by Jaeb Center For Health Research 2017 - 2025
- Novartis DRC Basic human research study of novel glaucoma endpoints and identification of optimal patient populations for neuroprotection trials awarded by Novartis Pharma AG 2020 - 2025
- A MULTICENTER, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND TOLERABILITY OF FARICIMAB IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION awarded by Genentech, Inc. 2021 - 2024
- A Multi-Center, Randomized, Double-Masked Phase 2 Study to Assess Safety and Efficacy of ADVM-022 (AAV.7m8-aflibercept) in Anti-VEGF Treatment- Experienced Patients with Neovascular (Wet) Age-related Macular Degeneration (nAMD) awarded by Adverum Biotechnologies, Inc 2022 - 2024
- Genentech DRC A PHASE III, MULTICENTER, RANDOMIZED STUDY OF THE EFFICACY, SAFETY, AND PHARMACOKINETICS OF THE PORT DELIVERY SYSTEM WITH RANIBIZUMAB IN PATIENTS WITH DIABETIC RETINOPATHY (PAVILION) awarded by Genentech, Inc. 2020 - 2024
- A MULTICENTER, OPEN-LABEL EXTENSION STUDY TO EVALUATE THE LONG-TERM SAFETY AND TOLERABILITY OF FARICIMAB IN PATIENTS WITH DIABETIC MACULAR EDEMA awarded by Genentech, Inc. 2020 - 2024
- A 2-part study of an open-label multiple ascending dose (MAD) safety study, and a dose-finding single-masked comparative safety and preliminary efficacy study of intravitreal EYE103 (Restoret®) in a mixed population of participants with DME and NVAMD awarded by Eyebiotech Ltd. 2023 - 2024
- A Phase 1/2a, Randomized, Double-Blind, Placebo-Controlled, Multicenter Dose-Ranging Study to Evaluate the Safety and Tolerability of Oral PIPE-307 in Subjects with Relapsing-Remitting Multiple Sclerosis awarded by Pipeline Therapeutics, Inc 2022 - 2024
- A PHASE II, MULTICENTER, RANDOMIZED, DOUBLE MASKED, ACTIVE COMPARATOR-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY, SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF RO7200220 ADMINISTERED INTRAVITREALLY IN PATIENTS WITH DIABETIC MACULA awarded by Roche TCRC, Inc 2021 - 2024
- A PHASE II, MULTICENTER, RANDOMIZED, DOUBLE MASKED, ACTIVE COMPARATOR-CONTROLLED STUDY TO INVESTIGATE THE EFFICACY, SAFETY, TOLERABILITY, PHARMACOKINETICS, AND PHARMACODYNAMICS OF RO7200220 IN COMBINATION WITH RANIBIZUMB ADMINISTERED INTRAVITREALLY I awarded by Roche TCRC, Inc 2021 - 2024
- A Phase 2, Multicenter, Randomized, Parallel-Group, Double-Masked, 4-Arm, Sham-Controlled Study of the Efficacy, Safety, and Tolerability of ANX007 Administered by Intravitreal Injection in Patients with Geographic Atrophy (GA) Secondary to AMD awarded by Annexon Biosciences 2020 - 2023
- Genentech DRC A MULTICENTER, RANDOMIZED, VISUAL ASSESSOR-MASKED, ACTIVE-COMPARATOR STUDY OF THE EFFICACY, SAFETY, AND PHARMACOKINETICS OF THE PORT DELIVERY SYSTEM WITH RANIBIZUMAB IN PATIENTS WITH DIABETIC RETINOPATHY WITH OR WITHOUT DME awarded by Genentech, Inc. 2020 - 2023
- IONIS DRC A Phase 2, Placebo-Controlled, Double-Masked Study to Assess Safety and Efficacy of Multiple Doses of IONIS-FB-LRX, an Antisense Inhibitor of Complement Factor B, in Patients with Geographic Atrophy Secondary to AMD awarded by Ionis Pharmaceuticals Inc 2019 - 2023
- Diabetic Retinopathy Clinical Research Network (DRCR.net) awarded by Jaeb Center For Health Research 2010 - 2023
- ROCHE DRC PH 1 STUDY TO INVESTIGATE THE SAFETY, TOLERABILITY, AND PHARMACOKINETICS OF RO7250284 FOLLOWING ITV ADMINISTRATION OF UNMASKED MULTIPLE ASCENDING DOSES AND MASKED SUSTAINED DELIVERY FROM THE PORT DELIVERY SYSTEM IN PATIENTS WITH NAMD awarded by Hoffman-La Roche, Inc. 2020 - 2023
- Ripple DRC Ph 2 Evaluation of Safety and Efficacy of IBE-814 IVT Implant - A Sustained, Low Dose Dexamethasone Therapy for the Treatment of Patients with Diabetic Macular Edema (DMO) and Macular Edema due to Retinal Vein Occlusion (RVO). awarded by Ripple Therapeutics 2020 - 2023
- LMRI DRC Phase 3 Clinical Trial of CNTF for MacTel Type 2-NTMT-03 awarded by The Lowy Medical Research Institute 2017 - 2023
- A Ph3, Multicenter, Prospective, Randomized, Masked, Controlled, Safety/Efficacy Study of a Fluocinolone Acetonide Intravitreal 0.05 mg Insert (Yutiq 0.05 mg) in Subjects with Chronic Non-Infectious Uveitis Affecting the Posterior Segment of the Eye awarded by Eyepoint Pharmaceuticals 2021 - 2023
- A 52-week multicenter, randomized, double-masked, 2-arm parallel study to compare efficacy, safety and immunogenicity of SOK583A1 to Eylea, administered intravitreally, in patients with neovascular age-related macular degeneration. awarded by Hexal AG 2020 - 2023
- Genentech DRC A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE-MASKED, ACTIVE COMPARATOR-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF FARICIMAB IN PATIENTS WITH MACULAR EDEMA SECONDARY TO CENTRAL RETINAL VEIN OCCLUSION awarded by Genentech, Inc. 2020 - 2023
- GENENTECH DRC A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE-MASKED, ACTIVE COMPARATOR-CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF FARICIMAB IN PATIENTS WITH MACULAR EDEMA SECONDARY TO BRANCH RETINAL VEIN OCCLUSION awarded by Genentech, Inc. 2020 - 2023
- A PHASE 2A, RANDOMIZED, PLACEBO-CONTROLLED, DOSE-RANGING STUDY TO EVALUATE THE SAFETY AND EFFICACY OF PTC518 IN SUBJECTS WITH HUNTINGTON'S DISEASE awarded by PTC Therapeutics, Inc 2022 - 2023
- Evaluation of KPI-012's protective effects on RPE cells awarded by Combangio, Inc. 2022 - 2023
- A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE-MASKED, ACTIVE COMPARATOR¿CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF FARICIMAB IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION (TENAYA) awarded by Genentech, Inc. 2018 - 2023
- Randomized, Placebo-Controlled, Double-Masked Study of the Safety and Efficacy of Orally Administered APX3330 in Subjects with Moderately Severe to Severe Non-Proliferative Diabetic Retinopathy and Mild Proliferative Diabetic Retinopathy awarded by Ocuphire Pharma, Inc. 2021 - 2023
- Novartis DRC A 96-week, two-arm, randomized, single-masked, multi-center, phase III study assessing the efficacy and safety of brolucizumab 6 mg compared to panretinal photocoagulation laser in patients with proliferative diabetic retinopathy awarded by Novartis Pharma AG 2020 - 2023
- A Phase 1b, Prospective, Multicenter, Randomized, Single Masked, Sham-Controlled Study to Assess the Safety, Tolerability and Evidence of Activity of a Single Intravitreal Injection of UBX1325 in Patients with Diabetic Macular Edema (DME) awarded by UNITY Biotechnology 2020 - 2023
- IVERIC DRC PH 3 MULTICENTER, RANDOMIZED, DOUBLE-MASKED, SHAM-CONTROLLED CLINICAL TRIAL TO ASSESS THE SAFETY AND EFFICACY OF INTRAVITREAL ADMINISTRATION OF ZIMURA¿ (COMPLEMENT C5 INHIBITOR) IN PATIENTS WITH GEOGRAPHIC ATROPHY SECONDARY TO DRY AMD awarded by IVERIC bio, Inc. 2020 - 2023
- Evaluation of the Heidelberg Engineering SPECTRALIS with Flex Module for In-vivo Imaging in the Supine Position awarded by Heidelberg Engineering 2020 - 2022
- ONL DRC A Phase 1 Open-Label, Dose Escalation Study to Assess the Safety and Tolerability of Intravitreal ONL1204 in Patients with Macula-off, Rhegmatogenous Retinal Detachment awarded by ONL Therapeutics 2019 - 2022
- SCD DRC A Phase 3 Randomized, Double-Masked, Parallel Group, Multicenter Study to Compare the Efficacy, Safety, Tolerability, Pharmacokinetics and Immunogenicity between SCD411 and Eylea® in Subjects with Neovascular Age-related Macular Degeneration awarded by Sam Chun Dang Pharm. Co., Ltd 2019 - 2022
- A PHASE III, MULTICENTER, RANDOMIZED, DOUBLE-MASKED, ACTIVE COMPARATOR¿CONTROLLED STUDY TO EVALUATE THE EFFICACY AND SAFETY OF FARICIMAB IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION (LUCERNE) awarded by Genentech, Inc. 2018 - 2022
- A Phase 2a, Prospective, Multicenter, Randomized, Double-Masked, Sham-Controlled Study to Assess the Safety, Tolerability and Evidence of Activity of a Single Intravitreal Injection of UBX1325 in Patients with nAMD awarded by UNITY Biotechnology 2021 - 2022
- Novartis DRC A one-year, single-arm, open-label, multicenter study assessing the effect of brolucizumab on disease control in adult patients with suboptimal anatomically controlled neovascular age-related macular degeneration (SWIFT) awarded by Novartis Pharma AG 2020 - 2022
- Gemini DRC A Prospective Natural History Study to Evaluate Clinical Characteristics and Disease Progression in Subjects with Non-central Geographic Atrophy (GA) Who Are Carriers of High-risk Genetic Variants of Complement Factor H (CFH) awarded by Gemini Therapeutics 2018 - 2022
- Gemini DRC NH01 Genetic Screening and Registry Study to Evaluate Long-term Clinical Outcomes and Disease Progression in Subjects with Non-central GA Who Are Carriers of High-risk Genetic Complement Variants Associated with Dry AMD awarded by Gemini Therapeutics 2018 - 2022
- Roche DRC Multi-center, non-randomized, open-label, multiple ascending dose study to investigate the safety, tolerability,pharmacokinetics, and pharmacodynamics of RO7200394 following intravitreal administration in patients with nAMD awarded by Hoffman-La Roche, Inc. 2019 - 2022
- Gemini DRC A Multicenter, Open-label, Multiple Dose Study in Patients with Geographic Atrophy Secondary to Dry AMD to Evaluate the Safety, Tolerability, Pharmacodynamics, and Immunogenicity of Repeat Intravitreal Injections of GEM103 awarded by Gemini Therapeutics 2020 - 2022
- Genentech -A PHASE III RANDOMIZED, VISUAL ASSESSOR MASKED, ACTIVE COMPARATOR, MULTICENTER EVALUATION OF THE EFFICACY, SAFETY AND PHARMACOKINETICS OF THE RANIBIZUMAB PORT DELIVERY SYSTEM FOR SUSTAINED DELIVERY OF RANIBIZUMAB IN PATIENTS WITH nAMD awarded by Genentech, Inc. 2018 - 2022
- Brolucizumab Switch and Extend Ph IIIb Study: A Canadian, multi-center, single-arm, open label study assessing the efficacy and safety of brolucizumab 6mg in a Treat and Extend regimen in patients with nAMD with prior anti-VEGF exposure (PEREGRINE) awarded by Novartis Pharmaceuticals Corporation 2020 - 2022
- Novartis DRC A multicenter, randomized, double-masked Phase 3a study to assess safety and efficacy of brolucizumab 6mg dosed Q4 weeks compared to Q8 weeks in high anti-VEGF-need patients with neovascular age-related macular degeneration (nAMD) awarded by Novartis Pharmaceuticals Corporation 2018 - 2022
- A Phase I/II, open-label, multicentre, dose escalation study assessing the safety and tolerability of pEYS606 when administered by electrotransfer (ET) in the ciliary muscle of patients with non infectious posterior, intermediate or panuveitis. awarded by Eyevensys 2017 - 2022
- Regenxbio DRC A Phase I, Open-label, Multiple-cohort, Dose-escalation Study to Evaluate the Safety and Tolerability of Gene Therapy with RGX-314 in Subjects with Neovascular AMD (nAMD) awarded by Regenxbio, Inc. 2018 - 2022
- GEMINI DRC Ph1, Multicenter, Open-label, Single-dose, Dose-escalation Study in Patients with Geographic Atrophy (GA) Secondary to Dry AMD to Evaluate the Safety, Tolerability, Pharmacodynamics, and Immunogenicity of Intravitreal Injections of GEM103 awarded by Gemini Therapeutics 2019 - 2022
- Lumithera DRC A Double-Masked, Randomized, Sham-Controlled, Parallel Group, Multi-Center Study to Assess the Safety and Efficacy of Photobiomodulation (PBM) in Subjects with Dry Age-Related Macular Degeneration (AMD) (LIGHTSITE III) awarded by LumiThera, Inc. 2019 - 2022
- Novartis DRC HAWK Centralized Imaging and Adjudication services, RTH258A/C1001502/I150 RTH258A2301 awarded by Novartis Pharma AG 2020 - 2021
- Kato DRC Safety and Treatment Benefit of RESOLV ER¿ in Subjects with Mild to Moderate Non-Proliferative Diabetic Retinopathy awarded by Kato Pharmaceuticals, Inc 2019 - 2021
- A 48 Week Phase II, Randomized, Open-Label, Multicenter, Study to Evaluate the Efficacy and Safety of Two (2) EYS606 (pEYS606 administered by injection and electrotransfer to the ciliary muscle) Treatment Regimens in Patients with CNIU awarded by Eyevensys 2019 - 2021
- LMRI DRC MacTel Phase II awarded by The Lowy Medical Research Institute 2013 - 2021
- Santen DRC AVANTE Study (Phase II) - Assess Efficacy, Safety of Intravitreal Injections of DE-122 in combination with Lucentis® Compared to Lucentis® Monotherapy in Subjects with Wet AMD awarded by Santen, Ltd. 2017 - 2021
- Regeneron DRC A Randomized, Single-Masked, Active-Controlled Phase 2 Study of the Safety, Tolerability, and Efficacy of Repeated Doses of High Dose Aflibercept in Patients with Neovascular Age-Related Macular Degeneration awarded by Regeneron Pharmaceuticals, Inc. 2019 - 2021
- Hemera DRC A Phase 2 Multi-Center Trial Evaluating Intravitreal AAVCAGsCD59 Compared to Sham Injection for the Treatment of Advanced Dry Age-Related Macular Degeneration with Geographic Atrophy awarded by Hemera Biosciences 2020 - 2021
- QLT DRC RET IRD 04: A Study of the Efficacy and Safety of QLT091001 in Subjects with Inherited Retinal Disease (IRD) Caused by Mutation in Retinal Pigment Epithelium Protein 65 (RPE65) or Lecithin:Retinol Acyltransferase (LRAT) awarded by QLT, Inc. 2016 - 2021
- A PHASE 2/3 RANDOMIZED, DOUBLE-MASKED, SHAM-CONTROLLED TRIAL OF QPI-1007 DELIVERED BY SINGLE OR MULTI-DOSE INTRAVITREAL INJECTIONS TO SUBJECTS WITH ACUTE NON ARTERITIC ANTERIOR ISCHEMIC OPTIC NEUROPATHY (NAION) awarded by Quark Pharmaceuticals, Inc 2015 - 2021
- Senju DRC A Double-Masked, Randomized, Multicenter, Placebo-Controlled, Parallel-Group Study to Assess the Safety, Tolerability, and Efficacy of MT-0814 for the Treatment of Patients with Age-Related Macular Degeneration awarded by Senju Pharmaceutical Co, Ltd. 2019 - 2021
- Astellas DRC Phase 1b, Dose Escalation Evaluation of Safety and Tolerability and a Ph 2, Randomized, Parallel Group, Controlled, Proof of Concept Investigation of Efficacy and Safety of ASP7317 for Atrophy Secondary to AMD awarded by Astellas Institute for Regenerative Medicine 2017 - 2021
- A PHASE IIIb OPEN-LABEL, SINGLE-ARM STUDY IN PATIENTS WITH NEOVASCULAR AGE-RELATED MACULAR DEGENERATION TO EVALUATE THE USABILITY OF RANIBIZUMAB 10 mg/0.1 mL PREFILLED SYRINGE WITH THE PORT DELIVERY SYSTEM awarded by Genentech, Inc. 2020 - 2021
- Thrombogenics DRC A Phase 1, open-label, multicenter, dose escalation study to evaluate the safety and tolerability of a single intravitreal injection of THR-687 for the treatment of diabetic macular edema (DME) awarded by ThromboGenics Inc 2018 - 2021
- Thrombogenics DRC - A Phase 1, open-label, multicenter, dose escalation study to evaluate the safety and tolerability of a single intravitreal injection of THR-149 for the treatment of diabetic macular edema (DME) awarded by ThromboGenics Inc 2018 - 2021
- UPENN - Additional Analysis of Data from the Comparison of Age-related Macular Degeneration Treatments Trials CATT and CATT Follow-up Study (CATT FS) awarded by University of Pennsylvania 2019 - 2021
- Mallinckrodt DRC A Multicenter, Open Label Pilot Study to Explore the Efficacy and Safety of H.P. Acthar® Gel in Subjects With Severe Noninfectious Intermediate, Posterior, or Panuveitis awarded by Mallinckrodt Pharmaceuticals 2019 - 2020
- Allgenesis DRC A Multicenter, Prospective, Randomized, Double-masked Study Evaluating the Safety, Tolerability, and Efficacy of Topical AG-86893 in Patients with Pterygium awarded by Allgenesis Biotherapeutics 2018 - 2020
- Evaluation of retinal cavitations in macular telangiectasia type 2 and response to ciliary neutrophic factor (CNTF) awarded by VitreoRetinal Surgery Foundation 2018 - 2020
- DRC Editas Natural History Study of CEP290-Related Retinal Degeneration awarded by Editas Medicine Inc. 2018 - 2020
- An Observational Change-From-Baseline Evaluation of Corneal Endothelial Cell Density in Eyes Treated with a Flucinolone Acetonide Intravitreal Implant awarded by Bausch & Lomb Incorporated 2016 - 2020
- AN OBSERVATIONAL BILATERAL EVALUATION OF CORNEAL ENDOTHELIAL CELL DENSITY IN SUBJECTS WHO HAVE HAD A FLUOCINOLONE ACETONIDE IMPLANT FOR AT LEAST ONE YEAR awarded by Bausch & Lomb Incorporated 2016 - 2020
- A PHASE Ib STUDY EVALUATING COBIMETINIB PLUS ATEZOLIZUMAB IN PATIENTS WITH ADVANCED BRAFV600 WILD-TYPE MELANOMA WHO HAVE PROGRESSED DURING OR AFTER TREATMENT WITH ANTI¿PD-1 THERAPY awarded by F. Hoffmann-La Roche Ltd 2017 - 2020
- Macular Edema Treatment Trials Associated with MUST (META-MUST) awarded by Johns Hopkins University 2016 - 2020
- A Multi-Center, Open-Label, Parallel-Arm, Randomized, Dose-Ranging Study of ENV515 (travoprost) Intracameral Implant in Subjects with Bilateral Ocular Hypertension or Early Primary Open-Angle Glaucoma awarded by Envisia Therapeutics 2015 - 2020
- A CONTROLLED, MULTI-CENTER STUDY OF THE UTILIZATION AND SAFETY OF THE MK II INSERTER AND THE SAFETY OF THE FAI INSERT IN SUBJECTS WITH NON-INFECTIOUS UVEITIS AFFECTING THE POSTERIOR SEGMENT OF THE EYE awarded by pSivida Corporation 2016 - 2020
- A RANDOMIZED, CONTROLLED, DOUBLE-MASKED, CROSSOVER CLINICAL TRIAL DESIGNED TO EVALUATE THE SAFETY AND EXPLORATORY EFFICACY OF 1.0 mg LUMINATE® (ALG-1001) AS A TREATMENT FOR NON-EXUDATIVE MACULAR DEGENERATION awarded by Allegro Ophthalmics, LLC 2017 - 2019
- Ophthotech DRC Phase 2 OPH2007 - A Phase 2A Open-Label Trial to ASSESS the Safety of Zimura¿ (anti-c5) Administered in Combination With Lucentis® 0.5 mg in Treatment naive subjecTs with Neovascular Age related macular degeneration awarded by Ophthotech Corp. 2018 - 2019
- pSivida PSV-FAI-001 Duke as Site awarded by pSivida Corporation 2013 - 2019
- SciFluor DRC Wet AMD study awarded by SciFluor Life Sciences 2018 - 2019
- A prospective, single-center, randomized, double masked, sham controlled study to evaluate the safety, efficacy and tolerability of OTX-TI (sustained release travoprost) Intracameral Depot compared to topical travoprost in subjects with OA & OHT. awarded by Ocular Therapeutix Inc 2017 - 2019
- PRN/Stealth DRC An Open-Label, Phase 1 Clinical Study to Evaluate the Safety and Tolerability of Subcutaneous Elamipretide in Subjects with Intermediate Age-Related Macular Degeneration awarded by PRN Pharmaceutical Research Network, LLC 2016 - 2018
- Computer Aided Classification of Diabetic Macular Edema awarded by National Institutes of Health 2012 - 2018
- A Randomized, Double Masked, Active Controlled Phase 2 Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal REGN910-3 in Patients with Neovascular Age-Related Macular Degeneration awarded by Regeneron Pharmaceuticals, Inc. 2016 - 2018
- A Randomized, Double Masked, Active Controlled Phase 2 Study of the Efficacy, Safety, and Tolerability of Repeated Doses of Intravitreal REGN910-3 in Patients with Diabetic Macular Edema awarded by Regeneron Pharmaceuticals, Inc. 2016 - 2018
- Acucela DRC A Phase 2a Multicenter, Randomized, Masked Study Evaluating the Pharmacodynamics of Emixustat Hydrochloride in Subjects with Macular Atrophy Secondary to Stargardt Disease awarded by Acucela Inc. 2016 - 2018
- A Phase 1, Dose-Escalation/Dose-Expansion Study Evaluating the Safety, Pharmacokinetics, and Pharmacodynamic Effects of Orally Administered CB-5083 in Subjects with Lymphoid Hematological Malignancies awarded by Cleave Biosciences 2016 - 2018
- ThromboGenics DRC OASIS study - provide raw images awarded by ThromboGenics Inc 2017 - 2018
- A Phase 1b/2a, Randomized, Double-Blinded, Placebo-Controlled, Multicenter Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of BMS-936559 in Subjects with Severe Sepsis awarded by Bristol-Myers Squibb Company 2015 - 2017
- UPenn - NEI Follow-up Study: Comparison of AMD Treatment Trials (CATT) YR3 awarded by University of Pennsylvania 2013 - 2017
- Neurotech DRC NT-503 (GEN 3) awarded by Neurotech USA, Inc. 2014 - 2017
- Evaluate Systemic Immunosuppression Regimens as Graft Rejection Prophylaxis Following Sub-retinal Transplantation of Human Embryonic Stem Cell Derived Retinal Pigmented Epithelial Cells in Patients with Geographic Atrophy Secondary to AMD awarded by Ocata Therapeutics, Inc. 2015 - 2017
- Competitive Renewal for Multicenter Uveitis Steroid Treatment (MUST) Trial awarded by Johns Hopkins University 2009 - 2017
- A Randomized-Withdrawal, Double-Masked, Placebo-Controlled Study of the Efficacy and Safety of Gevokizumab in Treating Subjects with Behcet's Disease Uveitis awarded by XOMA (US) LLC 2014 - 2017
- River Vision DRC DME awarded by River Vision Development Corporation 2014 - 2017
- Alcon DRC OVID II RTH255-P001 awarded by Alcon Research, Inc. 2015 - 2017
- A 12-month study to investigate the efficacy, safety and pharmacokinetics of a monthly dosing regimen of ranibizumab (0.5 mg) in combination with pegpleranib (1.5mg), compared to monthly raranibizumab (0.5 mg) monotherapy, in patients with nAMD awarded by Novartis Pharma AG 2016
- A 12-month, multi-center, open-label study to investigate the safety of pegpleranib (1.5 mg) in combination with anti-VEGF agents, ranibizumab (0.5 mg) or aflibercept (2 mg), in Japanese patients with neovascular age-related macular degeneration awarded by Novartis Pharma AG 2016
- Coordinating Center for the Comparison of AMD Treatments Trials awarded by University of Pennsylvania 2014 - 2015
- Comparison of AMD Treatment Trials-OCT Reading Center awarded by National Institutes of Health 2006 - 2013
- CATT OCT Reading Center awarded by National Institutes of Health 2009 - 2011
- Cytokine Modulation in Proliferative Vitreoretinopathy awarded by National Institutes of Health 1992 - 2006
- Cytokine Modulation In Proleferative Vitreoretinopathy awarded by National Institutes of Health 1997 - 1999
- Cytokine Modulation In Proliferative Vitreoretinopathy awarded by National Institutes of Health 1996
- Cytokine Modulation In Proliferative Vtreoretinopathy awarded by National Institutes of Health 1992 - 1996
- Modulation Of Na+K+ Atpase In Retinal Detachment awarded by National Institutes of Health 1989 - 1990
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External Relationships
- 4D Molecular Therapeutics
- Adverum Biotechnoligies
- Annexon Biosciences, Inc.
- BlueRock Therapeutics
- EyePoint
- Gemini Therapeuticx
- Genentech Roche
- Iveric Bio
- Neurotech
- Novartis
- Oxurion
- Publications & Artistic Works
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Selected Publications
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Books
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Jaffe, G. J., P. Ashton, and P. A. Pearson. Preface, 2006.
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Jaffe, G. J., P. Ashton, and P. A. Pearson. Intraocular drug delivery, 2006.
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Academic Articles
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Deaner, Jordan D., Danny Mammo, Andrew Gross, Terry Lee, Sumit Sharma, Sunil K. Srivastava, Glenn J. Jaffe, and Dilraj S. Grewal. “0.18 mg fluocinolone acetonide insert for the treatment of chronic post-operative pseudophakic cystoid macular edema.” Retina, February 15, 2023. https://doi.org/10.1097/IAE.0000000000003765.Full Text Link to Item
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Lad, Eleonora M., Jacque L. Duncan, Wendi Liang, Maureen G. Maguire, Allison R. Ayala, Isabelle Audo, David G. Birch, et al. “Baseline Microperimetry and OCT in the RUSH2A Study: Structure-Function Association and Correlation With Disease Severity.” Am J Ophthalmol 244 (December 2022): 98–116. https://doi.org/10.1016/j.ajo.2022.08.013.Full Text Link to Item
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Abraham, Joseph R., Glenn J. Jaffe, Peter K. Kaiser, Stephanie J. Chiu, Jessica Loo, Sina Farsiu, Laurens Bouckaert, et al. “Impact of Baseline Quantitative OCT Features on Response to Risuteganib for the Treatment of Dry Age-Related Macular Degeneration: The Importance of Outer Retinal Integrity.” Ophthalmol Retina 6, no. 11 (November 2022): 1019–27. https://doi.org/10.1016/j.oret.2022.05.002.Full Text Link to Item
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Jabs, Douglas A., Peter McCluskey, Alan G. Palestine, Jennifer E. Thorne, and Jennifer E. Standardization of Uveitis Nomenclature (SUN) Working Group. “The standardisation of uveitis nomenclature (SUN) project.” Clin Exp Ophthalmol, September 27, 2022. https://doi.org/10.1111/ceo.14175.Full Text Link to Item
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Jaffe, Glenn J., Briana Cameron, David Kardatzke, Jane Ives, Giulio Barteselli, and Shamika Gune. “Prevalence and Progression of Macular Atrophy in Eyes with Neovascular Age-Related Macular Degeneration in the Phase 2 Ladder Trial of the Port Delivery System with Ranibizumab.” Ophthalmol Retina 6, no. 9 (September 2022): 786–95. https://doi.org/10.1016/j.oret.2022.04.006.Full Text Link to Item
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Khanani, Arshad M., David M. Brown, Glenn J. Jaffe, Charles C. Wykoff, Eser Adiguzel, Randall Wong, Xiangyi Meng, Jeffrey S. Heier, and Jeffrey S. MERLIN Investigators. “MERLIN: Phase 3a, Multicenter, Randomized, Double-Masked Trial of Brolucizumab in Participants with Neovascular Age-Related Macular Degeneration and Persistent Retinal Fluid.” Ophthalmology 129, no. 9 (September 2022): 974–85. https://doi.org/10.1016/j.ophtha.2022.04.028.Full Text Link to Item
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Loo, Jessica, Glenn J. Jaffe, Jacque L. Duncan, David G. Birch, and Sina Farsiu. “VALIDATION OF A DEEP LEARNING-BASED ALGORITHM FOR SEGMENTATION OF THE ELLIPSOID ZONE ON OPTICAL COHERENCE TOMOGRAPHY IMAGES OF AN USH2A-RELATED RETINAL DEGENERATION CLINICAL TRIAL.” Retina 42, no. 7 (July 1, 2022): 1347–55. https://doi.org/10.1097/IAE.0000000000003448.Full Text Link to Item
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Ogura, Yuichiro, Glenn J. Jaffe, Chui Ming Gemmy Cheung, Gregg T. Kokame, Tomohiro Iida, Kanji Takahashi, Won Ki Lee, et al. “Efficacy and safety of brolucizumab versus aflibercept in eyes with polypoidal choroidal vasculopathy in Japanese participants of HAWK.” Br J Ophthalmol 106, no. 7 (July 2022): 994–99. https://doi.org/10.1136/bjophthalmol-2021-319090.Full Text Link to Item
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Thomas, Akshay S., Luc Duchateau, Petra Kozma-Wiebe, and Glenn Jaffe. “Resolution of outer retinal abnormalities in eyes with vitreomacular traction without macular hole in the OASIS trial.” Br J Ophthalmol, March 14, 2022. https://doi.org/10.1136/bjophthalmol-2021-319500.Full Text Link to Item
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Jaffe, Glenn J. “Bacillary Layer Retinal Detachment in Neovascular Age-Related Macular Degeneration.” Ophthalmol Retina 6, no. 3 (March 2022): 183–84. https://doi.org/10.1016/j.oret.2021.11.002.Full Text Link to Item
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Wu, Zhichao, Maximilian Pfau, Barbara A. Blodi, Frank G. Holz, Glenn J. Jaffe, Sandra Liakopoulos, Srinivas R. Sadda, et al. “OCT Signs of Early Atrophy in Age-Related Macular Degeneration: Interreader Agreement: Classification of Atrophy Meetings Report 6.” Ophthalmol Retina 6, no. 1 (January 2022): 4–14. https://doi.org/10.1016/j.oret.2021.03.008.Full Text Link to Item
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Dugel, Pravin U., Arshad M. Khanani, Brian B. Berger, Sunil Patel, Mitchell Fineman, Glenn J. Jaffe, Petra Kozma-Wiebe, and Jeffrey Heier. “Phase 1 Dose-Escalation Study of Plasma Kallikrein Inhibitor THR-149 for the Treatment of Diabetic Macular Edema.” Transl Vis Sci Technol 10, no. 14 (December 1, 2021): 28. https://doi.org/10.1167/tvst.10.14.28.Full Text Link to Item
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Jaffe, Glenn J., Keith Westby, Karl G. Csaky, Jordi Monés, Joel A. Pearlman, Sunil S. Patel, Brian C. Joondeph, John Randolph, Harvey Masonson, and Kourous A. Rezaei. “Reply.” Ophthalmology 128, no. 12 (December 2021): e219–20. https://doi.org/10.1016/j.ophtha.2021.08.019.Full Text Link to Item
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Sun, Jennifer K., Kristin Josic, Michele Melia, Adam R. Glassman, Clare Bailey, Kakarla V. Chalam, Emily Y. Chew, et al. “Conversion of Central Subfield Thickness Measurements of Diabetic Macular Edema Across Cirrus and Spectralis Optical Coherence Tomography Instruments.” Transl Vis Sci Technol 10, no. 14 (December 1, 2021): 34. https://doi.org/10.1167/tvst.10.14.34.Full Text Link to Item
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Chan, Clement K., Calvin E. Mein, Adam R. Glassman, Wesley T. Beaulieu, Claire T. Calhoun, Glenn J. Jaffe, Lee M. Jampol, et al. “Pneumatic Vitreolysis with Perfluoropropane for Vitreomacular Traction with and without Macular Hole: DRCR Retina Network Protocols AG and AH.” Ophthalmology 128, no. 11 (November 2021): 1592–1603. https://doi.org/10.1016/j.ophtha.2021.05.005.Full Text Link to Item
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Core, Jason Q., Maxwell Pistilli, Ebenezer Daniel, Juan E. Grunwald, Cynthia A. Toth, Glenn J. Jaffe, Peiying Hua, et al. “Predominantly Persistent Subretinal Fluid in the Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmol Retina 5, no. 10 (October 2021): 962–74. https://doi.org/10.1016/j.oret.2021.06.003.Full Text Link to Item
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Grewal, Dilraj S., Glenn J. Jaffe, and Robert T. Keenan. “SARILUMAB FOR RECALCITRANT CYSTOID MACULAR EDEMA IN NON-PARANEOPLASTIC AUTOIMMUNE RETINOPATHY.” Retin Cases Brief Rep 15, no. 5 (September 1, 2021): 504–8. https://doi.org/10.1097/ICB.0000000000000872.Full Text Link to Item
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Jaffe, Glenn J., Usha Chakravarthy, K Bailey Freund, Robyn H. Guymer, Frank G. Holz, Sandra Liakopoulos, Jordi M. Monés, et al. “Imaging Features Associated with Progression to Geographic Atrophy in Age-Related Macular Degeneration: Classification of Atrophy Meeting Report 5.” Ophthalmol Retina 5, no. 9 (September 2021): 855–67. https://doi.org/10.1016/j.oret.2020.12.009.Full Text Link to Item
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Khanani, Arshad M., Sunil S. Patel, Victor H. Gonzalez, Suk J. Moon, Glenn J. Jaffe, John A. Wells, Petra Kozma, Pravin U. Dugel, and Raj K. Maturi. “Phase 1 Study of THR-687, a Novel, Highly Potent Integrin Antagonist for the Treatment of Diabetic Macular Edema.” Ophthalmol Sci 1, no. 3 (September 2021): 100040. https://doi.org/10.1016/j.xops.2021.100040.Full Text Link to Item
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Kim, Dong Yoon, Jessica Loo, Sina Farsiu, and Glenn J. Jaffe. “COMPARISON OF SINGLE DRUSEN SIZE ON COLOR FUNDUS PHOTOGRAPHY AND SPECTRAL-DOMAIN OPTICAL COHERENCE TOMOGRAPHY.” Retina 41, no. 8 (August 1, 2021): 1715–22. https://doi.org/10.1097/IAE.0000000000003099.Full Text Link to Item
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Monés, Jordi, Sunil K. Srivastava, Glenn J. Jaffe, Ramin Tadayoni, Thomas A. Albini, Peter K. Kaiser, Frank G. Holz, et al. “Risk of Inflammation, Retinal Vasculitis, and Retinal Occlusion-Related Events with Brolucizumab: Post Hoc Review of HAWK and HARRIER.” Ophthalmology 128, no. 7 (July 2021): 1050–59. https://doi.org/10.1016/j.ophtha.2020.11.011.Full Text Link to Item
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Suhler, Eric B., Glenn J. Jaffe, Eric Fortin, Lyndell L. Lim, Pauline T. Merrill, Andrew D. Dick, Antoine P. Brezin, et al. “Long-Term Safety and Efficacy of Adalimumab in Patients with Noninfectious Intermediate Uveitis, Posterior Uveitis, or Panuveitis.” Ophthalmology 128, no. 6 (June 2021): 899–909. https://doi.org/10.1016/j.ophtha.2020.10.036.Full Text Link to Item
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Jaffe, Glenn J., Keith Westby, Karl G. Csaky, Jordi Monés, Joel A. Pearlman, Sunil S. Patel, Brian C. Joondeph, John Randolph, Harvey Masonson, and Kourous A. Rezaei. “Reply.” Ophthalmology 128, no. 5 (May 2021): e26–27. https://doi.org/10.1016/j.ophtha.2020.12.031.Full Text Link to Item
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Brodie, Frank L., and Glenn J. Jaffe. “Choroidal Neovascularization in Familial Transthyretin Amyloidosis.” Retina 41, no. 5 (May 1, 2021): e44–45. https://doi.org/10.1097/IAE.0000000000003165.Full Text Link to Item
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Tomkins-Netzer, Oren, Susan L. Lightman, Alyce E. Burke, Elizabeth A. Sugar, Lyndell L. Lim, Glenn J. Jaffe, Michael M. Altaweel, et al. “Seven-Year Outcomes of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial and Follow-up Study Results.” Ophthalmology 128, no. 5 (May 2021): 719–28. https://doi.org/10.1016/j.ophtha.2020.08.035.Full Text Link to Item
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Jaffe, Glenn J., Keith Westby, Karl G. Csaky, Jordi Monés, Joel A. Pearlman, Sunil S. Patel, Brian C. Joondeph, John Randolph, Harvey Masonson, and Kourous A. Rezaei. “C5 Inhibitor Avacincaptad Pegol for Geographic Atrophy Due to Age-Related Macular Degeneration: A Randomized Pivotal Phase 2/3 Trial.” Ophthalmology 128, no. 4 (April 2021): 576–86. https://doi.org/10.1016/j.ophtha.2020.08.027.Full Text Link to Item
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Finn, Avni P., Maxwell Pistilli, Vincent Tai, Ebenezer Daniel, Gui-Shuang Ying, Maureen G. Maguire, Juan E. Grunwald, et al. “Localized Optical Coherence Tomography Precursors of Macular Atrophy and Fibrotic Scar in the Comparison of Age-Related Macular Degeneration Treatments Trials.” Am J Ophthalmol 223 (March 2021): 338–47. https://doi.org/10.1016/j.ajo.2020.11.002.Full Text Link to Item
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Kumar, Jaya B., Sandra Stinnett, Jung Il Han, and Glenn J. Jaffe. “Reply.” Retina 41, no. 3 (March 1, 2021): e39. https://doi.org/10.1097/IAE.0000000000003121.Full Text Link to Item
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Yang, Ping, Samantha E. Neal, Kristen L. Buehne, Grace M. Tewkesbury, Mikael Klingeborn, Yae-Young Yang, Peter Baciu, and Glenn J. Jaffe. “Complement-mediated release of fibroblast growth factor 2 from human RPE cells.” Exp Eye Res 204 (March 2021): 108471. https://doi.org/10.1016/j.exer.2021.108471.Full Text Link to Item
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Brodie, Frank, Michael Repka, Stephen Allan Burns, S Grace Prakalapakorn, Christie Morse, Joel S. Schuman, Michael R. Duenas, et al. “Development, Validation, and Innovation in Ophthalmic Laser-Based Imaging: Report From a US Food and Drug Administration-Cosponsored Forum.” Jama Ophthalmol 139, no. 1 (January 1, 2021): 113–18. https://doi.org/10.1001/jamaophthalmol.2020.4994.Full Text Link to Item
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Jaffe, G. J. “The utility of CAM OCT criteria for AMD clinical trials.” Retina Today 2021, no. May-June (January 1, 2021): 41–42.
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Cheong, Kai Xiong, Dilraj Singh Grewal, Kelvin Yi Chong Teo, Alfred Tau Liang Gan, Glenn Jay Jaffe, and Gemmy Chui Ming Cheung. “The relationship between pigment epithelial detachment and visual outcome in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.” Eye (Lond) 34, no. 12 (December 2020): 2257–63. https://doi.org/10.1038/s41433-020-0803-6.Full Text Link to Item
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Bodaghi, B., Q. D. Nguyen, G. Jaffe, R. Khoramnia, and C. Pavesio. “Preventing relapse in non-infectious uveitis affecting the posterior segment of the eye – evaluating the 0.2 μg/day fluocinolone acetonide intravitreal implant (ILUVIEN®).” Journal of Ophthalmic Inflammation and Infection 10, no. 1 (December 1, 2020). https://doi.org/10.1186/s12348-020-00225-z.Full Text
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Duncan, Jacque L., Wendi Liang, Maureen G. Maguire, Isabelle Audo, Allison R. Ayala, David G. Birch, Joseph Carroll, et al. “Baseline Visual Field Findings in the RUSH2A Study: Associated Factors and Correlation With Other Measures of Disease Severity.” Am J Ophthalmol 219 (November 2020): 87–100. https://doi.org/10.1016/j.ajo.2020.05.024.Full Text Open Access Copy Link to Item
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Jaffe, Glenn J., Carlos E. Pavesio, and Carlos E. Study Investigators. “Effect of a Fluocinolone Acetonide Insert on Recurrence Rates in Noninfectious Intermediate, Posterior, or Panuveitis: Three-Year Results.” Ophthalmology 127, no. 10 (October 2020): 1395–1404. https://doi.org/10.1016/j.ophtha.2020.04.001.Full Text Link to Item
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Yang, Ping, Zixuan Shao, Nicholas A. Besley, Samantha E. Neal, Kristen L. Buehne, John Park, Hampar Karageozian, et al. “Risuteganib Protects against Hydroquinone-induced Injury in Human RPE Cells.” Invest Ophthalmol Vis Sci 61, no. 10 (August 3, 2020): 35. https://doi.org/10.1167/iovs.61.10.35.Full Text Link to Item
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Kumar, Jaya B., Sandra Stinnett, Jung I. L. Han, and Glenn J. Jaffe. “CORRELATION OF SUBRETINAL HYPERREFLECTIVE MATERIAL MORPHOLOGY AND VISUAL ACUITY IN NEOVASCULAR AGE-RELATED MACULAR DEGENERATION.” Retina 40, no. 5 (May 2020): 845–56. https://doi.org/10.1097/IAE.0000000000002552.Full Text Link to Item
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Cai, Cindy X., Cindy Skalak, Robert T. Keenan, Dilraj S. Grewal, and Glenn J. Jaffe. “Time to disease recurrence in noninfectious uveitis following long-acting injectable fluocinolone acetonide implant.” Graefes Arch Clin Exp Ophthalmol 258, no. 5 (May 2020): 1023–30. https://doi.org/10.1007/s00417-020-04614-x.Full Text Link to Item
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Sadda, SriniVas R., Robyn Guymer, Jordi M. Monés, Adnan Tufail, and Glenn J. Jaffe. “Anti-Vascular Endothelial Growth Factor Use and Atrophy in Neovascular Age-Related Macular Degeneration: Systematic Literature Review and Expert Opinion.” Ophthalmology 127, no. 5 (May 2020): 648–59. https://doi.org/10.1016/j.ophtha.2019.11.010.Full Text Link to Item
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Neal, Samantha E., Kristen L. Buehne, Nicholas A. Besley, Ping Yang, Peter Silinski, Jiyong Hong, Ian T. Ryde, Joel N. Meyer, and Glenn J. Jaffe. “Resveratrol Protects Against Hydroquinone-Induced Oxidative Threat in Retinal Pigment Epithelial Cells.” Invest Ophthalmol Vis Sci 61, no. 4 (April 9, 2020): 32. https://doi.org/10.1167/iovs.61.4.32.Full Text Link to Item
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Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group, Frederick L., Frederick L. Writing Committee:, Daniel F. Martin, Maureen G. Maguire, Stuart L. Fine, Gui-Shuang Ying, Glenn J. Jaffe, et al. “Ranibizumab and Bevacizumab for Treatment of Neovascular Age-related Macular Degeneration: Two-Year Results.” Ophthalmology 127, no. 4S (April 2020): S135–45. https://doi.org/10.1016/j.ophtha.2020.01.029.Full Text Link to Item
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Guymer, Robyn H., Philip J. Rosenfeld, Christine A. Curcio, Frank G. Holz, Giovanni Staurenghi, K Bailey Freund, Steffen Schmitz-Valckenberg, et al. “Incomplete Retinal Pigment Epithelial and Outer Retinal Atrophy in Age-Related Macular Degeneration: Classification of Atrophy Meeting Report 4.” Ophthalmology 127, no. 3 (March 2020): 394–409. https://doi.org/10.1016/j.ophtha.2019.09.035.Full Text Link to Item
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Scoles, Drew, Gui-Shuang Ying, Wei Pan, Peiying Hua, Juan E. Grunwald, Ebenezer Daniel, Glenn J. Jaffe, et al. “Characteristics of Eyes With Good Visual Acuity at 5 Years After Initiation of Treatment for Age-Related Macular Degeneration but Not Receiving Treatment From Years 3 to 5: Post Hoc Analysis of the CATT Randomized Clinical Trial.” Jama Ophthalmol 138, no. 3 (March 1, 2020): 276–84. https://doi.org/10.1001/jamaophthalmol.2019.5831.Full Text Link to Item
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Dugel, Pravin U., Adrian Koh, Yuichiro Ogura, Glenn J. Jaffe, Ursula Schmidt-Erfurth, David M. Brown, Andre V. Gomes, et al. “HAWK and HARRIER: Phase 3, Multicenter, Randomized, Double-Masked Trials of Brolucizumab for Neovascular Age-Related Macular Degeneration.” Ophthalmology 127, no. 1 (January 2020): 72–84. https://doi.org/10.1016/j.ophtha.2019.04.017.Full Text Link to Item
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Finn, Avni P., Robert T. Keenan, and Glenn J. Jaffe. “RECONSTITUTION OF THE ELLIPSOID ZONE WITH TOCILIZUMAB IN AUTOIMMUNE RETINOPATHY.” Retin Cases Brief Rep 14, no. 4 (2020): 297–300. https://doi.org/10.1097/ICB.0000000000000766.Full Text Link to Item
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Dugel, Pravin U., Adrian Koh, Yuichiro Ogura, Glenn J. Jaffe, Ursula Schmidt-Erfurth, David M. Brown, Andre V. Gomes, et al. “Reply.” Ophthalmology 126, no. 12 (December 2019): e96–97. https://doi.org/10.1016/j.ophtha.2019.08.016.Full Text Link to Item
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Cheung, Chui Ming Gemmy, Dilraj S. Grewal, Kelvin Yi Chong Teo, Alfred Gan, Aditi Mohla, Usha Chakravarthy, Tien Yin Wong, and Glenn J. Jaffe. “The Evolution of Fibrosis and Atrophy and Their Relationship with Visual Outcomes in Asian Persons with Neovascular Age-Related Macular Degeneration.” Ophthalmol Retina 3, no. 12 (December 2019): 1045–55. https://doi.org/10.1016/j.oret.2019.06.002.Full Text Link to Item
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Hsu, S Tammy, Hoan T. Ngo, Sandra S. Stinnett, Nathan L. Cheung, Robert J. House, Michael P. Kelly, Xi Chen, et al. “Assessment of Macular Microvasculature in Healthy Eyes of Infants and Children Using OCT Angiography.” Ophthalmology 126, no. 12 (December 2019): 1703–11. https://doi.org/10.1016/j.ophtha.2019.06.028.Full Text Open Access Copy Link to Item
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Albini, Thomas, Natalia F. Callaway, Glenn J. Jaffe, William Feuer, Janet Davis, Debra Goldstein, Careen Lowder, et al. “MUST Beg to Differ.” Ophthalmic Surg Lasers Imaging Retina 50, no. 5 (May 1, 2019): 266–68. https://doi.org/10.3928/23258160-20190503-01.Full Text Link to Item
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Thomas, Akshay S., Angel L. Hatef, Sandra S. Stinnett, Robert T. Keenan, and Glenn J. Jaffe. “PERIVASCULAR THICKENING ON OPTICAL COHERENCE TOMOGRAPHY AS A MARKER OF INFLAMMATION IN BIRDSHOT RETINOCHOROIDITIS.” Retina 39, no. 5 (May 2019): 956–63. https://doi.org/10.1097/IAE.0000000000002038.Full Text Link to Item
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Daniel, Ebenezer, Gui-Shuang Ying, Benjamin J. Kim, Cynthia A. Toth, Frederick Ferris, Daniel F. Martin, Juan E. Grunwald, et al. “Five-Year Follow-up of Nonfibrotic Scars in the Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmology 126, no. 5 (May 2019): 743–51. https://doi.org/10.1016/j.ophtha.2018.11.020.Full Text Link to Item
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Chew, Emily Y., Traci E. Clemons, Glenn J. Jaffe, Charles A. Johnson, Sina Farsiu, Eleonora M. Lad, Robyn Guymer, et al. “Effect of Ciliary Neurotrophic Factor on Retinal Neurodegeneration in Patients with Macular Telangiectasia Type 2: A Randomized Clinical Trial.” Ophthalmology 126, no. 4 (April 2019): 540–49. https://doi.org/10.1016/j.ophtha.2018.09.041.Full Text Link to Item
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Ervin, Ann-Margret, Rupert W. Strauss, Mohamed I. Ahmed, David Birch, Janet Cheetham, Frederick L. Ferris, Michael S. Ip, et al. “A Workshop on Measuring the Progression of Atrophy Secondary to Stargardt Disease in the ProgStar Studies: Findings and Lessons Learned.” Transl Vis Sci Technol 8, no. 2 (April 2019): 16. https://doi.org/10.1167/tvst.8.2.16.Full Text Link to Item
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Jaffe, Glenn J., C Stephen Foster, Carlos E. Pavesio, Dario A. Paggiarino, and Gerard E. Riedel. “Effect of an Injectable Fluocinolone Acetonide Insert on Recurrence Rates in Chronic Noninfectious Uveitis Affecting the Posterior Segment: Twelve-Month Results.” Ophthalmology 126, no. 4 (April 2019): 601–10. https://doi.org/10.1016/j.ophtha.2018.10.033.Full Text Link to Item
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Toth, Cynthia A., Vincent Tai, Maxwell Pistilli, Stephanie J. Chiu, Katrina P. Winter, Ebenezer Daniel, Juan E. Grunwald, et al. “Distribution of OCT Features within Areas of Macular Atrophy or Scar after 2 Years of Anti-VEGF Treatment for Neovascular AMD in CATT.” Ophthalmol Retina 3, no. 4 (April 2019): 316–25. https://doi.org/10.1016/j.oret.2018.11.011.Full Text Link to Item
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Thorne, Jennifer E., Elizabeth A. Sugar, Janet T. Holbrook, Alyce E. Burke, Michael M. Altaweel, Albert T. Vitale, Nisha R. Acharya, John H. Kempen, Douglas A. Jabs, and Douglas A. Multicenter Uveitis Steroid Treatment Trial Research Group. “Periocular Triamcinolone vs. Intravitreal Triamcinolone vs. Intravitreal Dexamethasone Implant for the Treatment of Uveitic Macular Edema: The PeriOcular vs. INTravitreal corticosteroids for uveitic macular edema (POINT) Trial.” Ophthalmology 126, no. 2 (February 2019): 283–95. https://doi.org/10.1016/j.ophtha.2018.08.021.Full Text Link to Item
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Yu, Jeannette J., Elvira Agrón, Traci E. Clemons, Amitha Domalpally, Freekje van Asten, Tiarnan D. Keenan, Catherine Cukras, Emily Y. Chew, and Emily Y. Age-Related Eye Disease Study 2 Research Group. “Natural History of Drusenoid Pigment Epithelial Detachment Associated with Age-Related Macular Degeneration: Age-Related Eye Disease Study 2 Report No. 17.” Ophthalmology 126, no. 2 (February 2019): 261–73. https://doi.org/10.1016/j.ophtha.2018.08.017.Full Text Link to Item
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Thomas, Akshay S., Francisco A. Folgar, Glenn J. Jaffe, Cynthia A. Toth, and Tamer H. Mahmoud. “Subfoveal Lucency after Treatment of Vitreomacular Traction without Macular Hole in the Phase 3 Trials of Ocriplasmin Vitreolysis.” Ophthalmol Retina 3, no. 1 (January 2019): 42–52. https://doi.org/10.1016/j.oret.2018.05.004.Full Text Link to Item
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Goto, Hiroshi, Masahiro Zako, Kenichi Namba, Noriyasu Hashida, Toshikatsu Kaburaki, Masanori Miyazaki, Koh-Hei Sonoda, et al. “Adalimumab in Active and Inactive, Non-Infectious Uveitis: Global Results from the VISUAL I and VISUAL II Trials.” Ocul Immunol Inflamm 27, no. 1 (2019): 40–50. https://doi.org/10.1080/09273948.2018.1491605.Full Text Link to Item
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Jampol, Lee M., Isoken Odia, Adam R. Glassman, Carl W. Baker, Anjali M. Bhorade, Dennis P. Han, Glenn J. Jaffe, et al. “PANRETINAL PHOTOCOAGULATION VERSUS RANIBIZUMAB FOR PROLIFERATIVE DIABETIC RETINOPATHY: Comparison of Peripapillary Retinal Nerve Fiber Layer Thickness in a Randomized Clinical Trial.” Retina 39, no. 1 (January 2019): 69–78. https://doi.org/10.1097/IAE.0000000000001909.Full Text Link to Item
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Agarwal, Aniruddha, Dilraj S. Grewal, Glenn J. Jaffe, Michael W. Stewart, Sunil Srivastava, and Vishali Gupta. “Current role of optical coherence tomography angiography: Expert panel discussion.” Indian J Ophthalmol 66, no. 12 (December 2018): 1696–99. https://doi.org/10.4103/ijo.IJO_1048_18.Full Text Link to Item
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Keenan, Tiarnan D., Elvira Agrón, Amitha Domalpally, Traci E. Clemons, Freekje van Asten, Wai T. Wong, Ronald G. Danis, et al. “Progression of Geographic Atrophy in Age-related Macular Degeneration: AREDS2 Report Number 16.” Ophthalmology 125, no. 12 (December 2018): 1913–28. https://doi.org/10.1016/j.ophtha.2018.05.028.Full Text Link to Item
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Ahmad, Meleha, Rosa Dolz-Marco, Yale L. Fisher, Lawrence A. Yannuzzi, Wenlan Zhang, Miguel Materin, and Glenn J. Jaffe. “Diagnostic and Therapeutic Challenges.” Retina 38, no. 11 (November 2018): 2260–66. https://doi.org/10.1097/IAE.0000000000001894.Full Text Link to Item
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Finn, Avni P., Akshay S. Thomas, Sandra S. Stinnett, Robert T. Keenan, Dilraj S. Grewal, and Glenn J. Jaffe. “The role of cystoid macular edema as a marker in the progression of non-paraneoplastic autoimmune retinopathy.” Graefes Arch Clin Exp Ophthalmol 256, no. 10 (October 2018): 1867–73. https://doi.org/10.1007/s00417-018-4084-8.Full Text Link to Item
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Jaffe, Glenn J. “DUKE ADVANCED VITREOUS SURGERY COURSE AND THE DUKE FELLOWS ADVANCED VITREOUS SURGERY COURSE.” Retina 38 Suppl 1 (September 2018): S1. https://doi.org/10.1097/IAE.0000000000002317.Full Text Link to Item
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Birnbaum, Faith A., Avni P. Finn, and Glenn J. Jaffe. “Bilateral Retinal Detachments Presenting With Acute Angle Closure.” Jama Ophthalmol 136, no. 8 (August 1, 2018): 954–55. https://doi.org/10.1001/jamaophthalmol.2017.6805.Full Text Link to Item
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Jaffe, G. J. “Less invasive treatment for uveitis.” Retina Today 2018, no. July-August (July 1, 2018): 53–55.
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Daniel, Ebenezer, Wei Pan, Gui-Shuang Ying, Benjamin J. Kim, Juan E. Grunwald, Frederick L. Ferris, Glenn J. Jaffe, et al. “Development and Course of Scars in the Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmology 125, no. 7 (July 2018): 1037–46. https://doi.org/10.1016/j.ophtha.2018.01.004.Full Text Link to Item
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Jampol, Lee M., Adam R. Glassman, Danni Liu, Lloyd Paul Aiello, Neil M. Bressler, Elia J. Duh, Susan Quaggin, John A. Wells, Charles C. Wykoff, and Charles C. Diabetic Retinopathy Clinical Research Network. “Plasma Vascular Endothelial Growth Factor Concentrations after Intravitreous Anti-Vascular Endothelial Growth Factor Therapy for Diabetic Macular Edema.” Ophthalmology 125, no. 7 (July 2018): 1054–63. https://doi.org/10.1016/j.ophtha.2018.01.019.Full Text Link to Item
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Suhler, Eric B., Alfredo Adán, Antoine P. Brézin, Eric Fortin, Hiroshi Goto, Glenn J. Jaffe, Toshikatsu Kaburaki, et al. “Safety and Efficacy of Adalimumab in Patients with Noninfectious Uveitis in an Ongoing Open-Label Study: VISUAL III.” Ophthalmology 125, no. 7 (July 2018): 1075–87. https://doi.org/10.1016/j.ophtha.2017.12.039.Full Text Link to Item
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Loo, Jessica, Leyuan Fang, David Cunefare, Glenn J. Jaffe, and Sina Farsiu. “Deep longitudinal transfer learning-based automatic segmentation of photoreceptor ellipsoid zone defects on optical coherence tomography images of macular telangiectasia type 2.” Biomed Opt Express 9, no. 6 (June 1, 2018): 2681–98. https://doi.org/10.1364/BOE.9.002681.Full Text Link to Item
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Ying, Gui-Shuang, Maureen G. Maguire, Wei Pan, Juan E. Grunwald, Ebenezer Daniel, Glenn J. Jaffe, Cynthia A. Toth, Stephanie A. Hagstrom, Daniel F. Martin, and Daniel F. CATT Research Group. “Baseline Predictors for Five-Year Visual Acuity Outcomes in the Comparison of AMD Treatment Trials.” Ophthalmol Retina 2, no. 6 (June 2018): 525–30. https://doi.org/10.1016/j.oret.2017.10.003.Full Text Link to Item
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Toth, Cynthia A., Vincent Tai, Stephanie J. Chiu, Katrina Winter, Monica B. Sevilla, Ebenezer Daniel, Juan E. Grunwald, et al. “Linking OCT, Angiographic, and Photographic Lesion Components in Neovascular Age-Related Macular Degeneration.” Ophthalmol Retina 2, no. 5 (May 2018): 481–93. https://doi.org/10.1016/j.oret.2017.09.016.Full Text Link to Item
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Thompson, Atalie C., Avni P. Finn, and Glenn J. Jaffe. “Chronic Inflammation After YAG Capsulotomy.” Jama Ophthalmol 136, no. 4 (April 1, 2018): 444–45. https://doi.org/10.1001/jamaophthalmol.2017.4372.Full Text Link to Item
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Sadda, Srinivas R., Robyn Guymer, Frank G. Holz, Steffen Schmitz-Valckenberg, Christine A. Curcio, Alan C. Bird, Barbara A. Blodi, et al. “Consensus Definition for Atrophy Associated with Age-Related Macular Degeneration on OCT: Classification of Atrophy Report 3.” Ophthalmology 125, no. 4 (April 2018): 537–48. https://doi.org/10.1016/j.ophtha.2017.09.028.Full Text Link to Item
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Jabs, Douglas A., Andrew Dick, John T. Doucette, Amod Gupta, Susan Lightman, Peter McCluskey, Annabelle A. Okada, et al. “Interobserver Agreement Among Uveitis Experts on Uveitic Diagnoses: The Standardization of Uveitis Nomenclature Experience.” Am J Ophthalmol 186 (February 2018): 19–24. https://doi.org/10.1016/j.ajo.2017.10.028.Full Text Link to Item
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Singh, Rishi P., Robert Lehmann, Joseph Martel, Kevin Jong, Ayala Pollack, Alexis Tsorbatzoglou, Giovanni Staurenghi, et al. “Re: Singh et al.: Nepafenac 0.3% after cataract surgery in patients with diabetic retinopathy: result of 2 randomized phase 3 studies (Ophthalmology. 2017; 124: 776-785) REPLY.” Ophthalmology 125, no. 1 (January 1, 2018): E9–10.Link to Item
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Singh, Rishi P., Robert Lehmann, Joseph Martel, Kevin Jong, Ayala Pollack, Alexis Tsorbatzoglou, Giovanni Staurenghi, et al. “Re: Re: Singh et al.: Nepafenac 0.3% after cataract surgery in patients with diabetic retinopathy: results of 2 randomized phase 3 studies (Ophthalmology. 2017;124:776-785) REPLY.” Ophthalmology 125, no. 1 (January 1, 2018): E11–12.Link to Item
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Maturi, Raj K., Adam R. Glassman, Danni Liu, Roy W. Beck, Abdhish R. Bhavsar, Neil M. Bressler, Lee M. Jampol, et al. “Effect of Adding Dexamethasone to Continued Ranibizumab Treatment in Patients With Persistent Diabetic Macular Edema: A DRCR Network Phase 2 Randomized Clinical Trial.” Jama Ophthalmol 136, no. 1 (January 1, 2018): 29–38. https://doi.org/10.1001/jamaophthalmol.2017.4914.Full Text Link to Item
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Singh, Rishi P., Robert Lehmann, Joseph Martel, Kevin Jong, Ayala Pollack, Alexis Tsorbatzoglou, Giovanni Staurenghi, et al. “Reply.” Ophthalmology 125, no. 1 (January 2018): e9–10. https://doi.org/10.1016/j.ophtha.2017.08.026.Full Text Link to Item
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Singh, Rishi P., Robert Lehmann, Joseph Martel, Kevin Jong, Ayala Pollack, Alexis Tsorbatzoglou, Giovanni Staurenghi, et al. “Reply.” Ophthalmology 125, no. 1 (January 2018): e11–12. https://doi.org/10.1016/j.ophtha.2017.08.023.Full Text Link to Item
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Singh, Rishi P., Robert Lehmann, Joseph Martel, Kevin Jong, Ayala Pollack, Alexis Tsorbatzoglou, Giovanni Staurenghi, et al. “Reply.” Ophthalmology 125, no. 1 (January 2018): e4–6. https://doi.org/10.1016/j.ophtha.2017.07.024.Full Text Link to Item
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Veerappan, Malini, David Fleischman, J Niklas Ulrich, Sandra S. Stinnett, Glenn J. Jaffe, and R Rand Allingham. “The Relationship of Vogt-Koyanagi-Harada Syndrome to Ocular Hypertension and Glaucoma.” Ocul Immunol Inflamm 25, no. 6 (December 2017): 748–52. https://doi.org/10.1080/09273948.2016.1189578.Full Text Link to Item
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Dugel, Pravin U., Glenn J. Jaffe, Peter Sallstig, James Warburton, Andreas Weichselberger, Mark Wieland, and Lawrence Singerman. “Brolucizumab Versus Aflibercept in Participants with Neovascular Age-Related Macular Degeneration: A Randomized Trial.” Ophthalmology 124, no. 9 (September 2017): 1296–1304. https://doi.org/10.1016/j.ophtha.2017.03.057.Full Text Link to Item
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Ong, Sally S., Edward G. Buckley, Brooks W. McCuen, Glenn J. Jaffe, Eric A. Postel, Tamer H. Mahmoud, Sandra S. Stinnett, Cynthia A. Toth, Lejla Vajzovic, and Prithvi Mruthyunjaya. “Comparison of Visual Outcomes in Coats' Disease: A 20-Year Experience.” Ophthalmology 124, no. 9 (September 2017): 1368–76. https://doi.org/10.1016/j.ophtha.2017.03.051.Full Text Link to Item
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Jaffe, Glenn J. “Reply.” Ophthalmology 124, no. 8 (August 2017): e62–63. https://doi.org/10.1016/j.ophtha.2017.03.024.Full Text Link to Item
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Böni, Christian, Jennifer E. Thorne, Richard F. Spaide, Trucian A. Ostheimer, David Sarraf, Ralph D. Levinson, Debra A. Goldstein, et al. “Fundus Autofluorescence Findings in Eyes With Birdshot Chorioretinitis.” Invest Ophthalmol Vis Sci 58, no. 10 (August 1, 2017): 4015–25. https://doi.org/10.1167/iovs.17-21897.Full Text Link to Item
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Yang, Ping, Nikolai P. Skiba, Grace M. Tewkesbury, Victoria M. Treboschi, Peter Baciu, and Glenn J. Jaffe. “Complement-Mediated Regulation of Apolipoprotein E in Cultured Human RPE Cells.” Invest Ophthalmol Vis Sci 58, no. 7 (June 1, 2017): 3073–85. https://doi.org/10.1167/iovs.16-20083.Full Text Open Access Copy Link to Item
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Singh, Rishi P., Robert Lehmann, Joseph Martel, Kevin Jong, Ayala Pollack, Alexis Tsorbatzoglou, Giovanni Staurenghi, et al. “Nepafenac 0.3% after Cataract Surgery in Patients with Diabetic Retinopathy: Results of 2 Randomized Phase 3 Studies.” Ophthalmology 124, no. 6 (June 2017): 776–85. https://doi.org/10.1016/j.ophtha.2017.01.036.Full Text Link to Item
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Grewal, Dilraj S., Matthew L. O’Sullivan, Martina Kron, and Glenn J. Jaffe. “Association of Disorganization of Retinal Inner Layers With Visual Acuity In Eyes With Uveitic Cystoid Macular Edema.” Am J Ophthalmol 177 (May 2017): 116–25. https://doi.org/10.1016/j.ajo.2017.02.017.Full Text Link to Item
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Mukherjee, Dibyendu, Eleonora M. Lad, Ryan R. Vann, Stephanie J. Jaffe, Traci E. Clemons, Martin Friedlander, Emily Y. Chew, Glenn J. Jaffe, Sina Farsiu, and Sina MacTel Study Group. “Correlation Between Macular Integrity Assessment and Optical Coherence Tomography Imaging of Ellipsoid Zone in Macular Telangiectasia Type 2.” Invest Ophthalmol Vis Sci 58, no. 6 (May 1, 2017): BIO291–99. https://doi.org/10.1167/iovs.17-21834.Full Text Link to Item
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Jaffe, Glenn J. “Reply.” Ophthalmology 124, no. 4 (April 2017): e45. https://doi.org/10.1016/j.ophtha.2016.08.045.Full Text Link to Item
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Jaffe, Glenn J. “Re: Jaffe et al.: Injectable fluocinolone acetonide long-acting implant for noninfectious intermediate uveitis, posterior uveitis, and panuveitis: two-year results REPLY.” Ophthalmology 124, no. 4 (April 1, 2017): E45–E45.Link to Item
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Grewal, Dilraj S., Seenu M. Hariprasad, and Glenn J. Jaffe. “Role of Disorganization of Retinal Inner Layers as an Optical Coherence Tomography Biomarker in Diabetic and Uveitic Macular Edema.” Ophthalmic Surg Lasers Imaging Retina 48, no. 4 (April 1, 2017): 282–88. https://doi.org/10.3928/23258160-20170329-02.Full Text Link to Item
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Holz, Frank G., SriniVas R. Sadda, Giovanni Staurenghi, Moritz Lindner, Alan C. Bird, Barbara A. Blodi, Ferdinando Bottoni, et al. “Imaging Protocols in Clinical Studies in Advanced Age-Related Macular Degeneration: Recommendations from Classification of Atrophy Consensus Meetings.” Ophthalmology 124, no. 4 (April 2017): 464–78. https://doi.org/10.1016/j.ophtha.2016.12.002.Full Text Link to Item
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Cadavid, Diego, Laura Balcer, Steven Galetta, Orhan Aktas, Tjalf Ziemssen, Ludo Vanopdenbosch, Jette Frederiksen, et al. “Safety and efficacy of opicinumab in acute optic neuritis (RENEW): a randomised, placebo-controlled, phase 2 trial.” Lancet Neurol 16, no. 3 (March 2017): 189–99. https://doi.org/10.1016/S1474-4422(16)30377-5.Full Text Link to Item
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Jaffe, Glenn J., Thomas A. Ciulla, Antonio P. Ciardella, Francois Devin, Pravin U. Dugel, Chiara M. Eandi, Harvey Masonson, et al. “Dual Antagonism of PDGF and VEGF in Neovascular Age-Related Macular Degeneration: A Phase IIb, Multicenter, Randomized Controlled Trial.” Ophthalmology 124, no. 2 (February 2017): 224–34. https://doi.org/10.1016/j.ophtha.2016.10.010.Full Text Link to Item
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Jaffe, Glenn J., and Glenn J. CATT Research Group. “Reply.” Ophthalmology 124, no. 2 (February 2017): e19. https://doi.org/10.1016/j.ophtha.2016.05.017.Full Text Link to Item
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Willoughby, Alex S., Stephanie J. Chiu, Rachel K. Silverman, Sina Farsiu, Clare Bailey, Henry E. Wiley, Frederick L. Ferris, and Glenn J. Jaffe. “Platform-Independent Cirrus and Spectralis Thickness Measurements in Eyes with Diabetic Macular Edema Using Fully Automated Software.” Transl Vis Sci Technol 6, no. 1 (February 2017): 9. https://doi.org/10.1167/tvst.6.1.9.Full Text Link to Item
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Zhang, Wenlan, Dilraj S. Grewal, Glenn J. Jaffe, Tamer H. Mahmoud, and Sharon Fekrat. “Spontaneous Closure of Full-Thickness Macular Hole With Epiretinal Membrane in Vitrectomized Eyes: Case Series and Review of Literature.” Ophthalmic Surg Lasers Imaging Retina 48, no. 2 (February 1, 2017): 183–90. https://doi.org/10.3928/23258160-20170130-15.Full Text Link to Item
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Daniel, Ebenezer, Juan E. Grunwald, Benjamin J. Kim, Maureen G. Maguire, Glenn J. Jaffe, Cynthia A. Toth, Frederick L. Ferris, et al. “Visual and Morphologic Outcomes in Eyes with Hard Exudate in the Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmol Retina 1, no. 1 (2017): 25–33. https://doi.org/10.1016/j.oret.2016.09.001.Full Text Link to Item
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Folgar, Francisco A., Glenn J. Jaffe, Cynthia A. Toth, and Tamer H. Mahmoud. “Recovery of Foveal Anatomy and Subfoveal Lucency after Pharmacologic and Surgical Macular Hole Closure in the Ocriplasmin Phase III Trials.” Ophthalmol Retina 1, no. 3 (2017): 240–48. https://doi.org/10.1016/j.oret.2016.11.013.Full Text Link to Item
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Grunwald, Juan E., Maxwell Pistilli, Ebenezer Daniel, Gui-Shuang Ying, Wei Pan, Glenn J. Jaffe, Cynthia A. Toth, et al. “Incidence and Growth of Geographic Atrophy during 5 Years of Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmology 124, no. 1 (January 2017): 97–104. https://doi.org/10.1016/j.ophtha.2016.09.012.Full Text Link to Item
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Tsai, Andrew S. H., Ning Cheung, Alfred T. L. Gan, Glenn J. Jaffe, Sobha Sivaprasad, Tien Yin Wong, and Chui Ming Gemmy Cheung. “Retinal angiomatous proliferation.” Surv Ophthalmol 62, no. 4 (2017): 462–92. https://doi.org/10.1016/j.survophthal.2017.01.008.Full Text Link to Item
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Altaweel, Michael M., Sapna S. Gangaputra, Jennifer E. Thorne, James P. Dunn, Susan G. Elner, Glenn J. Jaffe, Rosa Y. Kim, et al. “Morphological assessment of the retina in uveitis.” J Ophthalmic Inflamm Infect 6, no. 1 (December 2016): 33. https://doi.org/10.1186/s12348-016-0103-2.Full Text Link to Item
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McNabb, Ryan P., Dilraj S. Grewal, Rajvi Mehta, Stefanie G. Schuman, Joseph A. Izatt, Tamer H. Mahmoud, Glenn J. Jaffe, Prithvi Mruthyunjaya, and Anthony N. Kuo. “Wide field of view swept-source optical coherence tomography for peripheral retinal disease.” Br J Ophthalmol 100, no. 10 (October 2016): 1377–82. https://doi.org/10.1136/bjophthalmol-2015-307480.Full Text Link to Item
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Nguyen, Quan Dong, Pauline T. Merrill, Glenn J. Jaffe, Andrew D. Dick, Shree Kumar Kurup, John Sheppard, Ariel Schlaen, et al. “Adalimumab for prevention of uveitic flare in patients with inactive non-infectious uveitis controlled by corticosteroids (VISUAL II): a multicentre, double-masked, randomised, placebo-controlled phase 3 trial.” Lancet 388, no. 10050 (September 17, 2016): 1183–92. https://doi.org/10.1016/S0140-6736(16)31339-3.Full Text Link to Item
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Jaffe, Glenn J., Andrew D. Dick, Antoine P. Brézin, Quan Dong Nguyen, Jennifer E. Thorne, Philippe Kestelyn, Talin Barisani-Asenbauer, et al. “Adalimumab in Patients with Active Noninfectious Uveitis.” N Engl J Med 375, no. 10 (September 8, 2016): 932–43. https://doi.org/10.1056/NEJMoa1509852.Full Text Link to Item
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Jaffe, Glenn J., Phoebe Lin, Robert T. Keenan, Paul Ashton, Cindy Skalak, and Sandra S. Stinnett. “Injectable Fluocinolone Acetonide Long-Acting Implant for Noninfectious Intermediate Uveitis, Posterior Uveitis, and Panuveitis: Two-Year Results.” Ophthalmology 123, no. 9 (September 2016): 1940–48. https://doi.org/10.1016/j.ophtha.2016.05.025.Full Text Link to Item
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Jaffe, Glenn J., Peter K. Kaiser, Desmond Thompson, Andrea Gibson, Namrata Saroj, Robert Vitti, Alyson J. Berliner, and Jeffrey S. Heier. “Differential Response to Anti-VEGF Regimens in Age-Related Macular Degeneration Patients with Early Persistent Retinal Fluid.” Ophthalmology 123, no. 9 (September 2016): 1856–64. https://doi.org/10.1016/j.ophtha.2016.05.016.Full Text Link to Item
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Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group, Stuart L., Maureen G. Maguire, Daniel F. Martin, Gui-Shuang Ying, Glenn J. Jaffe, Ebenezer Daniel, Juan E. Grunwald, Cynthia A. Toth, Frederick L. Ferris, and Stuart L. Fine. “Five-Year Outcomes with Anti-Vascular Endothelial Growth Factor Treatment of Neovascular Age-Related Macular Degeneration: The Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmology 123, no. 8 (August 2016): 1751–61. https://doi.org/10.1016/j.ophtha.2016.03.045.Full Text Link to Item
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Jaffe, G. J. “Combination therapy for neovascular AMD: Could the combination of an anti-VEGF agent and an anti-PDGF drug solve some of the issues seen with anti-VEGF monotherapy? Trial data may soon tell.” Retina Today 2016July-August (July 1, 2016): 88–91.
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Jaffe, G. J. “Combination therapy for neovascular AMD: Could the combination of an anti-VEGF agent and an anti-PDGF drug solve some of the issues seen with anti-VEGF monotherapy? Trial data may soon tell.” Retina Today 2016July-August (July 1, 2016): 88–91.
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Waldstein, Sebastian M., Christian Simader, Giovanni Staurenghi, N Victor Chong, Paul Mitchell, Glenn J. Jaffe, Chengxing Lu, Todd A. Katz, and Ursula Schmidt-Erfurth. “Morphology and Visual Acuity in Aflibercept and Ranibizumab Therapy for Neovascular Age-Related Macular Degeneration in the VIEW Trials.” Ophthalmology 123, no. 7 (July 2016): 1521–29. https://doi.org/10.1016/j.ophtha.2016.03.037.Full Text Link to Item
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Böni, Christian, Jennifer E. Thorne, Richard F. Spaide, Trucian A. Ostheimer, David Sarraf, Ralph D. Levinson, Debra A. Goldstein, et al. “Choroidal Findings in Eyes With Birdshot Chorioretinitis Using Enhanced-Depth Optical Coherence Tomography.” Invest Ophthalmol Vis Sci 57, no. 9 (July 1, 2016): OCT591–99. https://doi.org/10.1167/iovs.15-18832.Full Text Link to Item
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Maguire, Maureen G., Gui-Shuang Ying, Glenn J. Jaffe, Cynthia A. Toth, Ebenezer Daniel, Juan Grunwald, Daniel F. Martin, Stephanie A. Hagstrom, and Stephanie A. CATT Research Group. “Single-Nucleotide Polymorphisms Associated With Age-Related Macular Degeneration and Lesion Phenotypes in the Comparison of Age-Related Macular Degeneration Treatments Trials.” Jama Ophthalmol 134, no. 6 (June 1, 2016): 674–81. https://doi.org/10.1001/jamaophthalmol.2016.0669.Full Text Link to Item
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Holbrook, Janet T., Elizabeth A. Sugar, Alyce E. Burke, Albert T. Vitale, Jennifer E. Thorne, Janet L. Davis, Douglas A. Jabs, and Douglas A. Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. “Dissociations of the Fluocinolone Acetonide Implant: The Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study.” Am J Ophthalmol 164 (April 2016): 29–36. https://doi.org/10.1016/j.ajo.2015.12.028.Full Text Link to Item
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Shah, Neepa, Maureen G. Maguire, Daniel F. Martin, James Shaffer, Gui-Shuang Ying, Juan E. Grunwald, Cynthia A. Toth, Glenn J. Jaffe, Ebenezer Daniel, and Ebenezer Comparison of Age-related Macular Degeneration Treatments Trials Research Group. “Angiographic Cystoid Macular Edema and Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmology 123, no. 4 (April 2016): 858–64. https://doi.org/10.1016/j.ophtha.2015.11.030.Full Text Link to Item
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Sharma, Sumit, Cynthia A. Toth, Ebenezer Daniel, Juan E. Grunwald, Maureen G. Maguire, Gui-Shuang Ying, Jiayan Huang, Daniel F. Martin, Glenn J. Jaffe, and Glenn J. Comparison of Age-related Macular Degeneration Treatments Trials Research Group. “Macular Morphology and Visual Acuity in the Second Year of the Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmology 123, no. 4 (April 2016): 865–75. https://doi.org/10.1016/j.ophtha.2015.12.002.Full Text Link to Item
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Chang, Petrus, Anna Tan, Glenn J. Jaffe, Monika Fleckenstein, Frank G. Holz, Steffen Schmitz-Valckenberg, and Steffen GAP Study Group. “Analysis of Peripapillary Atrophy in Relation to Macular Geographic Atrophy in Age-Related Macular Degeneration.” Invest Ophthalmol Vis Sci 57, no. 4 (April 1, 2016): 2277–82. https://doi.org/10.1167/iovs.15-18629.Full Text Link to Item
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Wiley, Henry E., Darby J. S. Thompson, Clare Bailey, Emily Y. Chew, Catherine A. Cukras, Glenn J. Jaffe, Richard W. J. Lee, et al. “A Crossover Design for Comparative Efficacy: A 36-Week Randomized Trial of Bevacizumab and Ranibizumab for Diabetic Macular Edema.” Ophthalmology 123, no. 4 (April 2016): 841–49. https://doi.org/10.1016/j.ophtha.2015.11.021.Full Text Link to Item
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Daniel, Ebenezer, James Shaffer, Gui-shuang Ying, Juan E. Grunwald, Daniel F. Martin, Glenn J. Jaffe, Maureen G. Maguire, and Maureen G. Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Research Group. “Outcomes in Eyes with Retinal Angiomatous Proliferation in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT).” Ophthalmology 123, no. 3 (March 2016): 609–16. https://doi.org/10.1016/j.ophtha.2015.10.034.Full Text Link to Item
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Oellers, Patrick, Glenn J. Jaffe, and Alan D. Proia. “Clinical-Pathological Correlation of Vogt-Koyanagi-Harada Disease.” Jama Ophthalmol 134, no. 3 (March 2016): 343–45. https://doi.org/10.1001/jamaophthalmol.2015.5464.Full Text Link to Item
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Schmitz-Valckenberg, Steffen, José-Alain Sahel, Ronald Danis, Monika Fleckenstein, Glenn J. Jaffe, Sebastian Wolf, Christian Pruente, and Frank G. Holz. “Natural History of Geographic Atrophy Progression Secondary to Age-Related Macular Degeneration (Geographic Atrophy Progression Study).” Ophthalmology 123, no. 2 (February 2016): 361–68. https://doi.org/10.1016/j.ophtha.2015.09.036.Full Text Link to Item
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Jaffe, Glenn J., Dean Eliott, John A. Wells, Jonathan L. Prenner, Andras Papp, and Samir Patel. “A Phase 1 Study of Intravitreous E10030 in Combination with Ranibizumab in Neovascular Age-Related Macular Degeneration.” Ophthalmology 123, no. 1 (January 2016): 78–85. https://doi.org/10.1016/j.ophtha.2015.09.004.Full Text Link to Item
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Reichel, Elias, Glenn J. Jaffe, Srinivas R. Sadda, Stefanie Schuman, Amir H. Hariri, Keegan Skidmore, and Jake Duker. “Prevalence of vitreomacular adhesion: an optical coherence tomography analysis in the retina clinic setting.” Clin Ophthalmol 10 (2016): 627–33. https://doi.org/10.2147/OPTH.S95524.Full Text Link to Item
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Moore, Daniel B., Sandra Stinnett, Glenn J. Jaffe, and Sanjay Asrani. “Improved Surgical Success of Combined Glaucoma Tube Shunt and Retisert(®) Implantation in Uveitic Eyes: A Retrospective Study.” Ophthalmol Ther 4, no. 2 (December 2015): 103–13. https://doi.org/10.1007/s40123-015-0041-3.Full Text Link to Item
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Jaffe, Glenn J., Steffen Schmitz-Valckenberg, David Boyer, Jeffrey Heier, Ute Wolf-Schnurrbusch, Giovanni Staurenghi, Ursula Schmidt-Erfurth, and Frank G. Holz. “Randomized Trial to Evaluate Tandospirone in Geographic Atrophy Secondary to Age-Related Macular Degeneration: The GATE Study.” Am J Ophthalmol 160, no. 6 (December 2015): 1226–34. https://doi.org/10.1016/j.ajo.2015.08.024.Full Text Link to Item
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Kempen, John H., Mark L. Van Natta, Michael M. Altaweel, James P. Dunn, Douglas A. Jabs, Susan L. Lightman, Jennifer E. Thorne, Janet T. Holbrook, and Janet T. Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. “Factors Predicting Visual Acuity Outcome in Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial.” Am J Ophthalmol 160, no. 6 (December 2015): 1133-1141.e9. https://doi.org/10.1016/j.ajo.2015.09.017.Full Text Link to Item
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Kempen, John H., Mark L. Van Natta, Michael M. Altaweel, James P. Dunn, Douglas A. Jabs, Susan L. Lightman, Jennifer E. Thorne, Janet T. Holbrook, and Janet T. Multicenter Uveitis Steroid Treatment (MUST) Trial Research Group. “Factors Predicting Visual Acuity Outcome in Intermediate, Posterior, and Panuveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial.” Am J Ophthalmol 160, no. 6 (December 2015): 1133-1141.e9. https://doi.org/10.1016/j.ajo.2015.09.017.Full Text Link to Item
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Ying, Gui-shuang, Maureen G. Maguire, Ebenezer Daniel, Frederick L. Ferris, Glenn J. Jaffe, Juan E. Grunwald, Cynthia A. Toth, Jiayan Huang, Daniel F. Martin, and Daniel F. Comparison of Age-Related Macular Degeneration Treatments Trials (CATT) Research Group. “Association of Baseline Characteristics and Early Vision Response with 2-Year Vision Outcomes in the Comparison of AMD Treatments Trials (CATT).” Ophthalmology 122, no. 12 (December 2015): 2523-31.e1. https://doi.org/10.1016/j.ophtha.2015.08.015.Full Text Link to Item
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Tomkins-Netzer, Oren, Susan Lightman, Lea Drye, John Kempen, Gary N. Holland, Narsing A. Rao, Richard J. Stawell, Albert Vitale, Douglas A. Jabs, and Douglas A. Multicenter Uveitis Steroid Treatment Trial Research Group. “Outcome of Treatment of Uveitic Macular Edema: The Multicenter Uveitis Steroid Treatment Trial 2-Year Results.” Ophthalmology 122, no. 11 (November 2015): 2351–59. https://doi.org/10.1016/j.ophtha.2015.07.036.Full Text Link to Item
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Munk, Marion R., Lee M. Jampol, Christian Simader, Wolfgang Huf, Tamara J. Mittermüller, Glenn J. Jaffe, and Ursula Schmidt-Erfurth. “Differentiation of Diabetic Macular Edema From Pseudophakic Cystoid Macular Edema by Spectral-Domain Optical Coherence Tomography.” Invest Ophthalmol Vis Sci 56, no. 11 (October 2015): 6724–33. https://doi.org/10.1167/iovs.15-17042.Full Text Link to Item
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Willoughby, Alex S., Gui-Shuang Ying, Cynthia A. Toth, Maureen G. Maguire, Russell E. Burns, Juan E. Grunwald, Ebenezer Daniel, Glenn J. Jaffe, and Glenn J. Comparison of Age-Related Macular Degeneration Treatments Trials Research Group. “Subretinal Hyperreflective Material in the Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmology 122, no. 9 (September 2015): 1846-53.e5. https://doi.org/10.1016/j.ophtha.2015.05.042.Full Text Link to Item
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Toth, Cynthia A., Francis Char Decroos, Gui-Shuang Ying, Sandra S. Stinnett, Cynthia S. Heydary, Russell Burns, Maureen Maguire, Daniel Martin, and Glenn J. Jaffe. “IDENTIFICATION OF FLUID ON OPTICAL COHERENCE TOMOGRAPHY BY TREATING OPHTHALMOLOGISTS VERSUS A READING CENTER IN THE COMPARISON OF AGE-RELATED MACULAR DEGENERATION TREATMENTS TRIALS.” Retina 35, no. 7 (July 2015): 1303–14. https://doi.org/10.1097/IAE.0000000000000483.Full Text Link to Item
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Ciulla, Thomas A., Gui-Shuang Ying, Maureen G. Maguire, Daniel F. Martin, Glenn J. Jaffe, Juan E. Grunwald, Ebenezer Daniel, Cynthia A. Toth, and Cynthia A. Comparison of Age-Related Macular Degeneration Treatments Trials Research Group. “Influence of the Vitreomacular Interface on Treatment Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials.” Ophthalmology 122, no. 6 (June 2015): 1203–11. https://doi.org/10.1016/j.ophtha.2015.02.031.Full Text Link to Item
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Gandorfer, Arnd, Matthew S. Benz, Julia A. Haller, Peter Stalmans, Stephen J. Pakola, Aniz Girach, Anselm Kampik, Cynthia A. Toth, Glenn J. Jaffe, and Glenn J. MIVI-TRUST Study Group. “Association between anatomical resolution and functional outcomes in the mivi-trust studies using ocriplasmin to treat symptomatic vitreomacular adhesion/vitreomacular traction, including when associated with macular hole.” Retina 35, no. 6 (June 2015): 1151–57. https://doi.org/10.1097/IAE.0000000000000508.Full Text Link to Item
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Mazumdar, Shahana, Neha Goel, Donald Park, and Brandon J. Lujan. “Diagnostic and therapeutic challenges.” Retina 35, no. 4 (April 2015): 829–33. https://doi.org/10.1097/IAE.0000000000000234.Full Text Link to Item
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Diabetic Retinopathy Clinical Research Network, Roy W., John A. Wells, Adam R. Glassman, Allison R. Ayala, Lee M. Jampol, Lloyd Paul Aiello, Andrew N. Antoszyk, et al. “Aflibercept, bevacizumab, or ranibizumab for diabetic macular edema.” N Engl J Med 372, no. 13 (March 26, 2015): 1193–1203. https://doi.org/10.1056/NEJMoa1414264.Full Text Link to Item
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Lou, Susan M., Kelly L. Larkin, Kevin Winthrop, James T. Rosenbaum, and James T. Uveitis Specialists Study Group. “Lack of consensus in the diagnosis and treatment for ocular tuberculosis among uveitis specialists.” Ocul Immunol Inflamm 23, no. 1 (February 2015): 25–31. https://doi.org/10.3109/09273948.2014.926936.Full Text Link to Item
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Bressler, Susan B., Allison R. Edwards, Christopher M. Andreoli, Paul Andrew Edwards, Adam R. Glassman, Glenn J. Jaffe, Michele Melia, Jennifer K. Sun, and Jennifer K. for the Diabetic Retinopathy Clinical Research Network/Writing Committee. “Reproducibility of Optovue RTVue Optical Coherence Tomography Retinal Thickness Measurements and Conversion to Equivalent Zeiss Stratus Metrics in Diabetic Macular Edema.” Transl Vis Sci Technol 4, no. 1 (January 2015): 5. https://doi.org/10.1167/tvst.4.1.5.Full Text Link to Item
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Haller, Julia A., Peter Stalmans, Matthew S. Benz, Arnd Gandorfer, Stephen J. Pakola, Aniz Girach, Anselm Kampik, Glenn J. Jaffe, Cynthia A. Toth, and Cynthia A. MIVI-TRUST Study Group. “Efficacy of intravitreal ocriplasmin for treatment of vitreomacular adhesion: subgroup analyses from two randomized trials.” Ophthalmology 122, no. 1 (January 2015): 117–22. https://doi.org/10.1016/j.ophtha.2014.07.045.Full Text Link to Item
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Korobelnik, Jean-François, Diana V. Do, Ursula Schmidt-Erfurth, David S. Boyer, Frank G. Holz, Jeffrey S. Heier, Edoardo Midena, et al. “Intravitreal aflibercept for diabetic macular edema.” Ophthalmology 121, no. 11 (November 2014): 2247–54. https://doi.org/10.1016/j.ophtha.2014.05.006.Full Text Link to Item
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Sugar, Elizabeth A., Janet T. Holbrook, John H. Kempen, Alyce E. Burke, Lea T. Drye, Jennifer E. Thorne, Thomas A. Louis, Douglas A. Jabs, Michael M. Altaweel, and Kevin D. Frick. “Cost-Effectiveness of Fluocinolone Acetonide Implant versus Systemic Therapy for Noninfectious Intermediate, Posterior, and Panuveitis.” Ophthalmology 121, no. 10 (October 2014): 1855–62. https://doi.org/10.1016/j.ophtha.2014.04.022.Full Text
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Diabetic Retinopathy Clinical Research Network Writing Committee, Oren Z., Susan B. Bressler, Allison R. Edwards, Kakarla V. Chalam, Neil M. Bressler, Adam R. Glassman, Glenn J. Jaffe, Michele Melia, David D. Saggau, and Oren Z. Plous. “Reproducibility of spectral-domain optical coherence tomography retinal thickness measurements and conversion to equivalent time-domain metrics in diabetic macular edema.” Jama Ophthalmol 132, no. 9 (September 2014): 1113–22. https://doi.org/10.1001/jamaophthalmol.2014.1698.Full Text Link to Item
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Walsh, David I., Gregory J. Sommer, Ulrich Y. Schaff, Paul S. Hahn, Glenn J. Jaffe, and Shashi K. Murthy. “A centrifugal fluidic immunoassay for ocular diagnostics with an enzymatically hydrolyzed fluorogenic substrate.” Lab Chip 14, no. 15 (August 7, 2014): 2673–80. https://doi.org/10.1039/c4lc00279b.Full Text Link to Item
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Ying, Gui-shuang, Benjamin J. Kim, Maureen G. Maguire, Jiayan Huang, Ebenezer Daniel, Glenn J. Jaffe, Juan E. Grunwald, et al. “Sustained visual acuity loss in the comparison of age-related macular degeneration treatments trials.” Jama Ophthalmol 132, no. 8 (August 2014): 915–21. https://doi.org/10.1001/jamaophthalmol.2014.1019.Full Text Link to Item
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Asrani, Sanjay, Daniel B. Moore, and Glenn J. Jaffe. “Paradoxical changes of retinal nerve fiber layer thickness in uveitic glaucoma.” Jama Ophthalmol 132, no. 7 (July 2014): 877–80. https://doi.org/10.1001/jamaophthalmol.2014.954.Full Text Link to Item
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Yang, Ping, Peter Baciu, Brittany C Parker Kerrigan, Menna Etheridge, Eric Sung, Brett A. Toimil, Jacob E. Berchuck, and Glenn J. Jaffe. “Retinal pigment epithelial cell death by the alternative complement cascade: role of membrane regulatory proteins, calcium, PKC, and oxidative stress.” Invest Ophthalmol Vis Sci 55, no. 5 (May 6, 2014): 3012–21. https://doi.org/10.1167/iovs.13-13554.Full Text Link to Item
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Daniel, E., C. A. Toth, J. E. Grunwald, G. J. Jaffe, D. F. Martin, S. L. Fine, J. Huang, et al. “Risk of scar in the comparison of Age-related Macular Degeneration Treatments Trials.” Ophthalmology 121, no. 3 (2014): 656–66.
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Walsh, D. I., S. K. Murthy, G. J. Sommer, U. Y. Schaff, P. S. Hahn, and G. J. Jaffe. “Lab-on-a-Disk Immunoassay for Ocular Diagnostics.” 40th Annual Northeast Bioengineering Conference, 2014.
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Lee, Joo Yong, Stephanie J. Chiu, Pratul P. Srinivasan, Joseph A. Izatt, Cynthia A. Toth, Sina Farsiu, and Glenn J. Jaffe. “Fully automatic software for retinal thickness in eyes with diabetic macular edema from images acquired by cirrus and spectralis systems.” Invest Ophthalmol Vis Sci 54, no. 12 (November 15, 2013): 7595–7602. https://doi.org/10.1167/iovs.13-11762.Full Text Link to Item
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Decroos, Francis Char, Sandra S. Stinnett, Cynthia S. Heydary, Russell E. Burns, and Glenn J. Jaffe. “Reading Center Characterization of Central Retinal Vein Occlusion Using Optical Coherence Tomography During the COPERNICUS Trial.” Transl Vis Sci Technol 2, no. 7 (November 2013): 7. https://doi.org/10.1167/tvst.2.7.7.Full Text Link to Item
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Hu, Peng, Rolf Herrmann, Amanda Bednar, Peter Saloupis, Mary A. Dwyer, Ping Yang, Xiaoping Qi, et al. “Aryl hydrocarbon receptor deficiency causes dysregulated cellular matrix metabolism and age-related macular degeneration-like pathology.” Proc Natl Acad Sci U S A 110, no. 43 (October 22, 2013): E4069–78. https://doi.org/10.1073/pnas.1307574110.Full Text Link to Item
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Pestana, N., D. Walsh, A. Hatch, P. Hahn, G. J. Jaffe, S. K. Murthy, and M. Niedre. “A dedicated low-cost fluorescence microfluidic device reader for point-of-care ocular diagnostics.” Journal of Medical Devices, Transactions of the Asme 7, no. 2 (June 24, 2013). https://doi.org/10.1115/1.4023995.Full Text
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Steinberg, Julia S., Jasmin Auge, Glenn J. Jaffe, Monika Fleckenstein, Frank G. Holz, Steffen Schmitz-Valckenberg, and Steffen GAP Study Group. “Longitudinal analysis of reticular drusen associated with geographic atrophy in age-related macular degeneration.” Invest Ophthalmol Vis Sci 54, no. 6 (June 10, 2013): 4054–60. https://doi.org/10.1167/iovs.12-11538.Full Text Link to Item
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Berchuck, Jacob E., Ping Yang, Brett A. Toimil, Zhe Ma, Peter Baciu, and Glenn J. Jaffe. “All-trans-retinal sensitizes human RPE cells to alternative complement pathway-induced cell death.” Invest Ophthalmol Vis Sci 54, no. 4 (April 12, 2013): 2669–77. https://doi.org/10.1167/iovs.12-11020.Full Text Link to Item
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Chalam, Kakarla V., Susan B. Bressler, Allison R. Edwards, Brian B. Berger, Neil M. Bressler, Adam R. Glassman, Sandeep Grover, Shailesh K. Gupta, and Jared S. Nielsen. “Retinal Thickness in People with Diabetes and Minimal or No Diabetic Retinopathy: Heidelberg Spectralis Optical Coherence Tomography.” Investigative Opthalmology &Amp; Visual Science 53, no. 13 (December 13, 2012): 8154–8154. https://doi.org/10.1167/iovs.12-10290.Full Text
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DeCroos, Francis Char, Cynthia A. Toth, Sandra S. Stinnett, Cynthia S. Heydary, Russell Burns, Glenn J. Jaffe, and Glenn J. CATT Research Group. “Optical coherence tomography grading reproducibility during the Comparison of Age-related Macular Degeneration Treatments Trials.” Ophthalmology 119, no. 12 (December 2012): 2549–57. https://doi.org/10.1016/j.ophtha.2012.06.040.Full Text Link to Item
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Folgar, Francisco A., Cynthia A. Toth, Francis Char DeCroos, Aniz Girach, Steve Pakola, and Glenn J. Jaffe. “Assessment of retinal morphology with spectral and time domain OCT in the phase III trials of enzymatic vitreolysis.” Invest Ophthalmol Vis Sci 53, no. 11 (October 25, 2012): 7395–7401. https://doi.org/10.1167/iovs.12-10379.Full Text Link to Item
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DeCroos, Francis Char, Cynthia A. Toth, Francisco A. Folgar, Stephen Pakola, Sandra S. Stinnett, Cynthia S. Heydary, Russell Burns, and Glenn J. Jaffe. “Characterization of vitreoretinal interface disorders using OCT in the interventional phase 3 trials of ocriplasmin.” Invest Ophthalmol Vis Sci 53, no. 10 (September 21, 2012): 6504–11. https://doi.org/10.1167/iovs.12-10370.Full Text Link to Item
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Scott, Adrienne W., Prithvi Mruthyunjaya, Rex M. McCallum, and Glenn J. Jaffe. “Diagnostic yield of vitreous biopsy in presumed sarcoidosis-related posterior segment inflammation.” Graefes Arch Clin Exp Ophthalmol 250, no. 9 (September 2012): 1379–85. https://doi.org/10.1007/s00417-012-1993-9.Full Text Link to Item
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Singh, R., L. Alpern, G. J. Jaffe, R. P. Lehmann, J. Lim, H. J. Reiser, K. Sall, T. Walters, and D. Sager. “Evaluation of nepafenac in prevention of macular edema following cataract surgery in patients with diabetic retinopathy.” Clinical Ophthalmology 6, no. 1 (August 2, 2012): 1259–69. https://doi.org/10.2147/OPTH.S31902.Full Text
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Mauschitz, Matthias M., Sofia Fonseca, Petrus Chang, Arno P. Göbel, Monika Fleckenstein, Glenn J. Jaffe, Frank G. Holz, Steffen Schmitz-Valckenberg, and Steffen GAP Study Group. “Topography of geographic atrophy in age-related macular degeneration.” Invest Ophthalmol Vis Sci 53, no. 8 (July 26, 2012): 4932–39. https://doi.org/10.1167/iovs.12-9711.Full Text Link to Item
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Comparison of Age-related Macular Degeneration Treatments Trials (CATT) Research Group, Frederick L., Daniel F. Martin, Maureen G. Maguire, Stuart L. Fine, Gui-shuang Ying, Glenn J. Jaffe, Juan E. Grunwald, Cynthia Toth, Maryann Redford, and Frederick L. Ferris. “Ranibizumab and bevacizumab for treatment of neovascular age-related macular degeneration: two-year results.” Ophthalmology 119, no. 7 (July 2012): 1388–98. https://doi.org/10.1016/j.ophtha.2012.03.053.Full Text Link to Item
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Taylor, Simon R. J., Susan L. Lightman, Elizabeth A. Sugar, Glen J. Jaffe, William R. Freeman, Michael M. Altaweel, Igor Kozak, Janet T. Holbrook, Douglas A. Jabs, and John H. Kempen. “The impact of macular edema on visual function in intermediate, posterior, and panuveitis.” Ocul Immunol Inflamm 20, no. 3 (June 2012): 171–81. https://doi.org/10.3109/09273948.2012.658467.Full Text Link to Item
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Sen, H Nida, Lea T. Drye, Debra A. Goldstein, Theresa A. Larson, Pauline T. Merrill, Peter R. Pavan, John D. Sheppard, Alyce Burke, Sunil K. Srivastava, and Douglas A. Jabs. “Hypotony in Patients with Uveitis: The Multicenter Uveitis Steroid Treatment (MUST) Trial.” Ocular Immunology and Inflammation 20, no. 2 (April 2012): 104–12. https://doi.org/10.3109/09273948.2011.647228.Full Text
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Frick, Kevin D., Lea T. Drye, John H. Kempen, James P. Dunn, Gary N. Holland, Paul Latkany, Narsing A. Rao, et al. “Associations among Visual Acuity and Vision- and Health-Related Quality of Life among Patients in the Multicenter Uveitis Steroid Treatment Trial.” Investigative Opthalmology &Amp; Visual Science 53, no. 3 (March 9, 2012): 1169–1169. https://doi.org/10.1167/iovs.11-8259.Full Text
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Jain, Nieraj, Sandra S. Stinnett, and Glenn J. Jaffe. “Prospective study of a fluocinolone acetonide implant for chronic macular edema from central retinal vein occlusion: thirty-six-month results.” Ophthalmology 119, no. 1 (January 2012): 132–37. https://doi.org/10.1016/j.ophtha.2011.06.019.Full Text Link to Item
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Dayani, Pouya N., Jessica Chow, Sandra S. Stinnett, and Glenn J. Jaffe. “Pars plana vitrectomy, fluocinolone acetonide implantation, and silicone oil infusion for the treatment of chronic, refractory uveitic hypotony.” Am J Ophthalmol 152, no. 5 (November 2011): 849-56.e1. https://doi.org/10.1016/j.ajo.2011.04.035.Full Text Link to Item
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Torre, Alejandra de-la-, Miles Stanford, Andre Curi, Glenn J. Jaffe, and Jorge E. Gomez-Marin. “Therapy for ocular toxoplasmosis.” Ocul Immunol Inflamm 19, no. 5 (October 2011): 314–20. https://doi.org/10.3109/09273948.2011.608915.Full Text Link to Item
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Schmitz-Valckenberg, Steffen, Christian K. Brinkmann, Florian Alten, Philipp Herrmann, Nina K. Stratmann, Arno P. Göbel, Monika Fleckenstein, Martin Diller, Glenn J. Jaffe, and Frank G. Holz. “Semiautomated image processing method for identification and quantification of geographic atrophy in age-related macular degeneration.” Invest Ophthalmol Vis Sci 52, no. 10 (September 29, 2011): 7640–46. https://doi.org/10.1167/iovs.11-7457.Full Text Link to Item
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Schmitz-Valckenberg, Steffen, Florian Alten, Julia S. Steinberg, Glenn J. Jaffe, Monika Fleckenstein, Bickol N. Mukesh, Thomas C. Hohman, Frank G. Holz, and Frank G. Geographic Atrophy Progression (GAP) Study Group. “Reticular drusen associated with geographic atrophy in age-related macular degeneration.” Invest Ophthalmol Vis Sci 52, no. 9 (August 24, 2011): 5009–15. https://doi.org/10.1167/iovs.11-7235.Full Text Link to Item
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Medearis, Sarah, Ian C. Han, Jessica K. Huang, Ping Yang, and Glenn J. Jaffe. “The role of Bcl-xL in mouse RPE cell survival.” Invest Ophthalmol Vis Sci 52, no. 9 (August 17, 2011): 6545–51. https://doi.org/10.1167/iovs.10-6772.Full Text Link to Item
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Gangaputra, Sapna S., Michael M. Altaweel, Qian Peng, David S. Friedman, P Kumar Rao, C Stephen Foster, Rosa Y. Kim, et al. “Morphologic Assessment for Glaucoma in the Multicenter Uveitis Steroid Treatment (MUST) Trial.” Ocular Immunology and Inflammation 19, no. 4 (August 2011): 267–74. https://doi.org/10.3109/09273948.2011.583376.Full Text
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CATT Research Group, Glenn J., Daniel F. Martin, Maureen G. Maguire, Gui-shuang Ying, Juan E. Grunwald, Stuart L. Fine, and Glenn J. Jaffe. “Ranibizumab and bevacizumab for neovascular age-related macular degeneration.” N Engl J Med 364, no. 20 (May 19, 2011): 1897–1908. https://doi.org/10.1056/NEJMoa1102673.Full Text Link to Item
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Zhang, Kang, Jill J. Hopkins, Jeffrey S. Heier, David G. Birch, Lawrence S. Halperin, Thomas A. Albini, David M. Brown, Glenn J. Jaffe, Weng Tao, and George A. Williams. “Ciliary neurotrophic factor delivered by encapsulated cell intraocular implants for treatment of geographic atrophy in age-related macular degeneration.” Proc Natl Acad Sci U S A 108, no. 15 (April 12, 2011): 6241–45. https://doi.org/10.1073/pnas.1018987108.Full Text Link to Item
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Han, Ian C., and Glenn J. Jaffe. “Evaluation of artifacts associated with macular spectral-domain optical coherence tomography.” Ophthalmology 117, no. 6 (June 2010): 1177-1189.e4. https://doi.org/10.1016/j.ophtha.2009.10.029.Full Text Link to Item
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Malone, Paula E., Leon W. Herndon, Kelly W. Muir, and Glenn J. Jaffe. “Combined fluocinolone acetonide intravitreal insertion and glaucoma drainage device placement for chronic uveitis and glaucoma.” Am J Ophthalmol 149, no. 5 (May 2010): 800-6.e1. https://doi.org/10.1016/j.ajo.2009.12.009.Full Text Link to Item
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“The Multicenter Uveitis Steroid Treatment Trial: Rationale, Design, and Baseline Characteristics.” American Journal of Ophthalmology 149, no. 4 (April 2010): 550-561.e10. https://doi.org/10.1016/j.ajo.2009.11.019.Full Text
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Castellano, Chelsea G., Sandra S. Stinnett, Priyatham S. Mettu, Rex M. McCallum, and Glenn J. Jaffe. “Retinal thickening in iridocyclitis.” Am J Ophthalmol 148, no. 3 (September 2009): 341–49. https://doi.org/10.1016/j.ajo.2009.03.034.Full Text Link to Item
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Yang, Ping, Jillian Tyrrell, Ian Han, and Glenn J. Jaffe. “Expression and modulation of RPE cell membrane complement regulatory proteins.” Invest Ophthalmol Vis Sci 50, no. 7 (July 2009): 3473–81. https://doi.org/10.1167/iovs.08-3202.Full Text Link to Item
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Han, Ian C., and Glenn J. Jaffe. “Comparison of spectral- and time-domain optical coherence tomography for retinal thickness measurements in healthy and diseased eyes.” Am J Ophthalmol 147, no. 5 (May 2009): 847-858.e1. https://doi.org/10.1016/j.ajo.2008.11.019.Full Text Link to Item
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Stepien, Kimberly E., Alexander M. Eaton, Glenn J. Jaffe, Janet L. Davis, Junaid Raja, and William Feuer. “Increased incidence of sterile endophthalmitis after intravitreal triamcinolone acetonide in spring 2006.” Retina 29, no. 2 (February 2009): 207–13. https://doi.org/10.1097/IAE.0b013e31818eccb3.Full Text Link to Item
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Chieh, Janet J., Alan N. Carlson, and Glenn J. Jaffe. “Combined fluocinolone acetonide intraocular delivery system insertion, phacoemulsification, and intraocular lens implantation for severe uveitis.” Am J Ophthalmol 146, no. 4 (October 2008): 589–94. https://doi.org/10.1016/j.ajo.2008.05.035.Full Text Link to Item
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Callanan, David G., Glenn J. Jaffe, Daniel F. Martin, P Andrew Pearson, and Timothy L. Comstock. “Treatment of posterior uveitis with a fluocinolone acetonide implant: three-year clinical trial results.” Arch Ophthalmol 126, no. 9 (September 2008): 1191–1201. https://doi.org/10.1001/archopht.126.9.1191.Full Text Link to Item
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Ramchandran, Rajeev S., Sharon Fekrat, Sandra S. Stinnett, and Glenn J. Jaffe. “Fluocinolone acetonide sustained drug delivery device for chronic central retinal vein occlusion: 12-month results.” Am J Ophthalmol 146, no. 2 (August 2008): 285–91. https://doi.org/10.1016/j.ajo.2008.03.025.Full Text Link to Item
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Jaffe, Glenn J. “Reimplantation of a fluocinolone acetonide sustained drug delivery implant for chronic uveitis.” Am J Ophthalmol 145, no. 4 (April 2008): 667–75. https://doi.org/10.1016/j.ajo.2007.11.008.Full Text Link to Item
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Ardoin, Stacy P., Deborah Kredich, Egla Rabinovich, Laura E. Schanberg, and Glenn J. Jaffe. “Infliximab to treat chronic noninfectious uveitis in children: retrospective case series with long-term follow-up.” Am J Ophthalmol 144, no. 6 (December 2007): 844–49. https://doi.org/10.1016/j.ajo.2007.08.018.Full Text Link to Item
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Goldstein, Debra A., David G. Godfrey, Anthony Hall, David G. Callanan, Glenn J. Jaffe, P Andrew Pearson, Dale W. Usner, and Timothy L. Comstock. “Intraocular pressure in patients with uveitis treated with fluocinolone acetonide implants.” Arch Ophthalmol 125, no. 11 (November 2007): 1478–85. https://doi.org/10.1001/archopht.125.11.ecs70063.Full Text Link to Item
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Zhang, Nanfei, James J. Peairs, Ping Yang, Jillian Tyrrell, Jennifer Roberts, Ryszard Kole, and Glenn J. Jaffe. “The importance of Bcl-xL in the survival of human RPE cells.” Invest Ophthalmol Vis Sci 48, no. 8 (August 2007): 3846–53. https://doi.org/10.1167/iovs.06-1145.Full Text Link to Item
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Yang, Ping, James J. Peairs, Ryotaro Tano, Nanfei Zhang, Jillian Tyrell, and Glenn J. Jaffe. “Caspase-8-mediated apoptosis in human RPE cells.” Invest Ophthalmol Vis Sci 48, no. 7 (July 2007): 3341–49. https://doi.org/10.1167/iovs.06-1340.Full Text Link to Item
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Zhang, Nanfei, Greg C. Hoffmeyer, Ellen S. Young, Russell E. Burns, Katrina P. Winter, Sandra S. Stinnett, Cynthia A. Toth, and Glenn J. Jaffe. “Optical coherence tomography reader agreement in neovascular age-related macular degeneration.” Am J Ophthalmol 144, no. 1 (July 2007): 37–44. https://doi.org/10.1016/j.ajo.2007.03.056.Full Text Link to Item
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Yang, Ping, James J. Peairs, Ryotaro Tano, and Glenn J. Jaffe. “Oxidant-mediated Akt activation in human RPE cells.” Invest Ophthalmol Vis Sci 47, no. 10 (October 2006): 4598–4606. https://doi.org/10.1167/iovs.06-0140.Full Text Link to Item
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Mruthyunjaya, Prithvi, Dara Khalatbari, Ping Yang, Sandra Stinnett, Ryotaro Tano, Paul Ashton, Hong Guo, Marty Nazzaro, and Glenn J. Jaffe. “Efficacy of low-release-rate fluocinolone acetonide intravitreal implants to treat experimental uveitis.” Arch Ophthalmol 124, no. 7 (July 2006): 1012–18. https://doi.org/10.1001/archopht.124.7.1012.Full Text Link to Item
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Jaffe, Glenn J., Daniel Martin, David Callanan, P Andrew Pearson, Brian Levy, Timothy Comstock, and Timothy Fluocinolone Acetonide Uveitis Study Group. “Fluocinolone acetonide implant (Retisert) for noninfectious posterior uveitis: thirty-four-week results of a multicenter randomized clinical study.” Ophthalmology 113, no. 6 (June 2006): 1020–27. https://doi.org/10.1016/j.ophtha.2006.02.021.Full Text Link to Item
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Rak, Daniel J., Katherine M. Hardy, Glenn J. Jaffe, and Brian S. McKay. “Ca++-switch induction of RPE differentiation.” Exp Eye Res 82, no. 4 (April 2006): 648–56. https://doi.org/10.1016/j.exer.2005.09.002.Full Text Link to Item
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Reeves, Sherman W., Frank A. Sloan, Paul P. Lee, and Glenn J. Jaffe. “Uveitis in the elderly: epidemiological data from the National Long-term Care Survey Medicare Cohort.” Ophthalmology 113, no. 2 (February 2006): 307.e1. https://doi.org/10.1016/j.ophtha.2005.10.008.Full Text Link to Item
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Cortez, Rafael, John P. Denny, Rafael Muci-Mendoza, Gema Ramirez, Darío Fuenmayor, and Glenn J. Jaffe. “Diffuse unilateral subacute neuroretinitis in Venezuela.” Ophthalmology 112, no. 12 (December 2005): 2110–14. https://doi.org/10.1016/j.ophtha.2005.05.029.Full Text Link to Item
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Cummings, Thomas J., Timothy T. Stenzel, Gordon Klintworth, and Glenn J. Jaffe. “Primary intraocular T-cell-rich large B-cell lymphoma.” Arch Pathol Lab Med 129, no. 8 (August 2005): 1050–53. https://doi.org/10.5858/2005-129-1050-PITLBL.Full Text Link to Item
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Jaffe, Glenn J., Rex M. McCallum, Brenda Branchaud, Cindy Skalak, Zuhal Butuner, and Paul Ashton. “Long-term follow-up results of a pilot trial of a fluocinolone acetonide implant to treat posterior uveitis.” Ophthalmology 112, no. 7 (July 2005): 1192–98. https://doi.org/10.1016/j.ophtha.2005.03.013.Full Text Link to Item
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Yang, Ping, Jessica L. Wiser, James J. Peairs, Jessica N. Ebright, Zachary J. Zavodni, Catherine Bowes Rickman, and Glenn J. Jaffe. “Human RPE expression of cell survival factors.” Invest Ophthalmol Vis Sci 46, no. 5 (May 2005): 1755–64. https://doi.org/10.1167/iovs.04-1039.Full Text Link to Item
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Ray, Robin, Sandra S. Stinnett, and Glenn J. Jaffe. “Evaluation of image artifact produced by optical coherence tomography of retinal pathology.” Am J Ophthalmol 139, no. 1 (January 2005): 18–29. https://doi.org/10.1016/j.ajo.2004.07.050.Full Text Link to Item
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Yang, Ping, Brian S. McKay, Janice B. Allen, and Glenn J. Jaffe. “Effect of NF-kappa B inhibition on TNF-alpha-induced apoptosis in human RPE cells.” Invest Ophthalmol Vis Sci 45, no. 7 (July 2004): 2438–46. https://doi.org/10.1167/iovs.03-0805.Full Text Link to Item
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Tseng, Wendy, Rafael T. Cortez, Gema Ramirez, Sandra Stinnett, and Glenn J. Jaffe. “Prevalence and risk factors for proliferative vitreoretinopathy in eyes with rhegmatogenous retinal detachment but no previous vitreoretinal surgery.” Am J Ophthalmol 137, no. 6 (June 2004): 1105–15. https://doi.org/10.1016/j.ajo.2004.02.008.Full Text Link to Item
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Khalatbari, Dara, Sandra Stinnett, Rex M. McCallum, and Glenn J. Jaffe. “Demographic-related variations in posterior segment ocular sarcoidosis.” Ophthalmology 111, no. 2 (February 2004): 357–62. https://doi.org/10.1016/S0161-6420(03)00793-0.Full Text Link to Item
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Jaffe, Glenn J., and Joseph Caprioli. “Optical coherence tomography to detect and manage retinal disease and glaucoma.” Am J Ophthalmol 137, no. 1 (January 2004): 156–69. https://doi.org/10.1016/s0002-9394(03)00792-x.Full Text Link to Item
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Park, Carl H., Glenn J. Jaffe, and Sharon Fekrat. “Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion.” Am J Ophthalmol 136, no. 3 (September 2003): 419–25. https://doi.org/10.1016/s0002-9394(03)00228-9.Full Text Link to Item
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Lai, James C., Sandra S. Stinnett, and Glenn J. Jaffe. “B-scan ultrasonography for the detection of macular thickening.” Am J Ophthalmol 136, no. 1 (July 2003): 55–61. https://doi.org/10.1016/s0002-9394(02)02273-0.Full Text Link to Item
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Stamer, W Daniel, Dean Bok, Jane Hu, Glenn J. Jaffe, and Brian S. McKay. “Aquaporin-1 channels in human retinal pigment epithelium: role in transepithelial water movement.” Invest Ophthalmol Vis Sci 44, no. 6 (June 2003): 2803–8. https://doi.org/10.1167/iovs.03-0001.Full Text Link to Item
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Yang, Ping, Brian S. McKay, Janice B. Allen, Wendy L. Roberts, and Glenn J. Jaffe. “Effect of mutant IkappaB on cytokine-induced activation of NF-kappaB in cultured human RPE cells.” Invest Ophthalmol Vis Sci 44, no. 3 (March 2003): 1339–47. https://doi.org/10.1167/iovs.02-0878.Full Text Link to Item
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Jaffe, Glenn J., Robert Brownlow, and John Hines. “Modified external needle drainage procedure for rhegmatogenous retinal detachment.” Retina 23, no. 1 (February 2003): 80–85. https://doi.org/10.1097/00006982-200302000-00013.Full Text Link to Item
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Meyer, Carsten H., Kazuki Hotta, Ward M. Peterson, Cynthia A. Toth, and Glenn J. Jaffe. “Effect of INS37217, a P2Y(2) receptor agonist, on experimental retinal detachment and electroretinogram in adult rabbits.” Invest Ophthalmol Vis Sci 43, no. 11 (November 2002): 3567–74.Link to Item
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Gilger, Brian C., Ping Yang, Jacklyn H. Salmon, Glenn J. Jaffe, and Janice B. Allen. “Expression of a chemokine by ciliary body epithelium in horses with naturally occurring recurrent uveitis and in cultured ciliary body epithelial cells.” Am J Vet Res 63, no. 7 (July 2002): 942–47. https://doi.org/10.2460/ajvr.2002.63.942.Full Text Link to Item
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Mruthyunjaya, Prithvi, J Michael Jumper, Rex McCallum, Divya J. Patel, Terry A. Cox, and Glenn J. Jaffe. “Diagnostic yield of vitrectomy in eyes with suspected posterior segment infection or malignancy.” Ophthalmology 109, no. 6 (June 2002): 1123–29. https://doi.org/10.1016/s0161-6420(02)01033-3.Full Text Link to Item
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Haupert, C. L., B. W. McCuen, G. J. Jaffe, E. R. Steuer, T. A. Cox, C. A. Toth, S. Fekrat, and E. A. Postel. “Pars plana vitrectomy, subretinal injection of tissue plasminogen activator, and fluid-gas exchange for displacement of thick submacular hemorrhage in age-related macular degeneration.” Am J Ophthalmol 131, no. 2 (February 2001): 208–15. https://doi.org/10.1016/s0002-9394(00)00734-0.Full Text Link to Item
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Elsing, S. H., E. A. Postel, M. K. Gill, L. M. Jampol, and G. J. Jaffe. “Management of eyes with both idiopathic macular hole and choroidal neovascularization.” Retina 21, no. 6 (2001): 613–18. https://doi.org/10.1097/00006982-200112000-00008.Full Text Link to Item
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Perkins, S. L., C. H. Yang, P. A. Ashton, and G. J. Jaffe. “Pharmacokinetics of the ganciclovir implant in the silicone-filled eye.” Retina 21, no. 1 (2001): 10–14. https://doi.org/10.1097/00006982-200102000-00002.Full Text Link to Item
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Jaffe, G. J., J. Ben-Nun, H. Guo, J. P. Dunn, and P. Ashton. “Fluocinolone acetonide sustained drug delivery device to treat severe uveitis.” Ophthalmology 107, no. 11 (November 2000): 2024–33. https://doi.org/10.1016/s0161-6420(00)00466-8.Full Text Link to Item
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Gilger, B. C., E. Malok, T. Stewart, D. Horohov, P. Ashton, T. Smith, G. J. Jaffe, and J. B. Allen. “Effect of an intravitreal cyclosporine implant on experimental uveitis in horses.” Vet Immunol Immunopathol 76, no. 3–4 (October 31, 2000): 239–55. https://doi.org/10.1016/s0165-2427(00)00219-1.Full Text Link to Item
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Bressler, N. M., S. B. Bressler, B. S. Hawkins, M. J. Marsh, P. Sternberg, M. A. Thomas, and M. A. Submacular Surgery Trials Pilot Study Investigators. “Submacular surgery trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: I. Ophthalmic outcomes submacular surgery trials pilot study report number 1.” Am J Ophthalmol 130, no. 4 (October 2000): 387–407. https://doi.org/10.1016/s0002-9394(00)00729-7.Full Text Link to Item
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Bressler, N. M., S. B. Bressler, B. S. Hawkins, M. J. Marsh, P. Sternberg, M. A. Thomas, and M. A. Submacular Surgery Trials Pilot Study Investigators. “Submacular surgery trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: I. Ophthalmic outcomes submacular surgery trials pilot study report number 1.” Am J Ophthalmol 130, no. 4 (October 2000): 387–407. https://doi.org/10.1016/s0002-9394(00)00729-7.Full Text Link to Item
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Jabs, D. A., J. T. Rosenbaum, C. S. Foster, G. N. Holland, G. J. Jaffe, J. S. Louie, R. B. Nussenblatt, et al. “Guidelines for the use of immunosuppressive drugs in patients with ocular inflammatory disorders: recommendations of an expert panel.” Am J Ophthalmol 130, no. 4 (October 2000): 492–513. https://doi.org/10.1016/s0002-9394(00)00659-0.Full Text Link to Item
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Jaffe, G. J., C. H. Yang, H. Guo, J. P. Denny, C. Lima, and P. Ashton. “Safety and pharmacokinetics of an intraocular fluocinolone acetonide sustained delivery device.” Invest Ophthalmol Vis Sci 41, no. 11 (October 2000): 3569–75.Link to Item
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“Submacular surgery trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: II. Quality of life outcomes submacular surgery trials pilot study report number 2.” Am J Ophthalmol 130, no. 4 (October 2000): 408–18. https://doi.org/10.1016/s0002-9394(00)00730-3.Full Text Link to Item
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“Submacular surgery trials randomized pilot trial of laser photocoagulation versus surgery for recurrent choroidal neovascularization secondary to age-related macular degeneration: II. Quality of life outcomes submacular surgery trials pilot study report number 2.” Am J Ophthalmol 130, no. 4 (October 2000): 408–18. https://doi.org/10.1016/s0002-9394(00)00730-3.Full Text Link to Item
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Stone, T. W., and G. J. Jaffe. “Reversible bull's-eye maculopathy associated with intravitreal fomivirsen therapy for cytomegalovirus retinitis.” Am J Ophthalmol 130, no. 2 (August 2000): 242–43. https://doi.org/10.1016/s0002-9394(00)00495-5.Full Text Link to Item
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Amin, H. I., H. R. McDonald, D. P. Han, G. J. Jaffe, M. W. Johnson, H. Lewis, P. F. Lopez, et al. “Vitrectomy update for macular traction in ocular toxocariasis.” Retina 20, no. 1 (2000): 80–85. https://doi.org/10.1097/00006982-200001000-00015.Full Text Link to Item
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Gallemore, R. P., J. M. Jumper, B. W. McCuen, G. J. Jaffe, E. A. Postel, and C. A. Toth. “Diagnosis of vitreoretinal adhesions in macular disease with optical coherence tomography.” Retina 20, no. 2 (2000): 115–20.Link to Item
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Gilger, B. C., E. Malok, T. Stewart, P. Ashton, T. Smith, G. J. Jaffe, and J. B. Allen. “Long-term effect on the equine eye of an intravitreal device used for sustained release of cyclosporine A.” Vet Ophthalmol 3, no. 2–3 (2000): 105–10. https://doi.org/10.1046/j.1463-5224.2000.00117.x.Full Text Link to Item
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Haupert, C. L., and G. J. Jaffe. “New and emerging treatments for patients with uveitis.” Int Ophthalmol Clin 40, no. 2 (2000): 205–20. https://doi.org/10.1097/00004397-200004000-00015.Full Text Link to Item
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Jaffe, G. J., P. A. Pearson, and P. Ashton. “Dexamethasone sustained drug delivery implant for the treatment of severe uveitis.” Retina 20, no. 4 (2000): 402–3. https://doi.org/10.1097/00006982-200004000-00015.Full Text Link to Item
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Jumper, J. M., R. Machemer, R. P. Gallemore, and G. J. Jaffe. “Exudative retinal detachment and retinitis associated with acquired syphilitic uveitis.” Retina 20, no. 2 (2000): 190–94.Link to Item
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Perkins, S. L., R. P. Gallemore, C. H. Yang, H. Guo, P. Ashton, and G. J. Jaffe. “Pharmacokinetics of the fluocinolone/5-fluorouracil codrug in the gas-filled eye.” Retina 20, no. 5 (2000): 514–19. https://doi.org/10.1097/00006982-200009000-00013.Full Text Link to Item
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Kylstra, J. A., J. C. Brown, G. J. Jaffe, T. A. Cox, R. Gallemore, C. M. Greven, J. G. Hall, and D. E. Eifrig. “The importance of fluorescein angiography in planning laser treatment of diabetic macular edema.” Ophthalmology 106, no. 11 (November 1999): 2068–73. https://doi.org/10.1016/S0161-6420(99)90485-2.Full Text Link to Item
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Montoya, J. G., S. Parmley, O. Liesenfeld, G. J. Jaffe, and J. S. Remington. “Use of the polymerase chain reaction for diagnosis of ocular toxoplasmosis.” Ophthalmology 106, no. 8 (August 1999): 1554–63. https://doi.org/10.1016/S0161-6420(99)90453-0.Full Text Link to Item
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Martin, D. F., J. P. Dunn, J. L. Davis, J. S. Duker, R. E. Engstrom, D. N. Friedberg, G. J. Jaffe, et al. “Use of the ganciclovir implant for the treatment of cytomegalovirus retinitis in the era of potent antiretroviral therapy: recommendations of the International AIDS Society-USA panel.” Am J Ophthalmol 127, no. 3 (March 1999): 329–39. https://doi.org/10.1016/s0002-9394(98)00441-3.Full Text Link to Item
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Wang, X. C., C. Jobin, J. B. Allen, W. L. Roberts, and G. J. Jaffe. “Suppression of NF-kappaB-dependent proinflammatory gene expression in human RPE cells by a proteasome inhibitor.” Invest Ophthalmol Vis Sci 40, no. 2 (February 1999): 477–86.Link to Item
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Dev, S., R. M. McCallum, and G. J. Jaffe. “Methotrexate treatment for sarcoid-associated panuveitis.” Ophthalmology 106, no. 1 (January 1999): 111–18. https://doi.org/10.1016/S0161-6420(99)90011-8.Full Text Link to Item
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Pearson, P. A., A. R. Piracha, H. A. Sen, and G. J. Jaffe. “Atovaquone for the treatment of toxoplasma retinochoroiditis in immunocompetent patients.” Ophthalmology 106, no. 1 (January 1999): 148–53. https://doi.org/10.1016/S0161-6420(99)90021-0.Full Text Link to Item
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Williams, D. F., E. J. Del Piero, P. J. Ferrone, G. J. Jaffe, H. R. McDonald, and M. A. Peters. “Management of complications in eyes containing two intraocular lenses.” Ophthalmology 105, no. 11 (November 1998): 2017–22. https://doi.org/10.1016/S0161-6420(98)91118-6.Full Text Link to Item
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Khawly, J. A., R. J. Lambert, and G. J. Jaffe. “Intraocular lens changes after short- and long-term exposure to intraocular silicone oil. An in vivo study.” Ophthalmology 105, no. 7 (July 1998): 1227–33. https://doi.org/10.1016/S0161-6420(98)97025-7.Full Text Link to Item
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Jaffe, G. J., C. S. Yang, X. C. Wang, S. W. Cousins, R. P. Gallemore, and P. Ashton. “Intravitreal sustained-release cyclosporine in the treatment of experimental uveitis.” Ophthalmology 105, no. 1 (January 1998): 46–56. https://doi.org/10.1016/s0161-6420(98)91176-9.Full Text Link to Item
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Yang, C. S., J. A. Khawly, D. P. Hainsworth, S. N. Chen, P. Ashton, H. Guo, and G. J. Jaffe. “An intravitreal sustained-release triamcinolone and 5-fluorouracil codrug in the treatment of experimental proliferative vitreoretinopathy.” Arch Ophthalmol 116, no. 1 (January 1998): 69–77. https://doi.org/10.1001/archopht.116.1.69.Full Text Link to Item
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Jaffe, G. J. “Management of condensation on a foldable acrylic intraocular lens after vitrectomy and fluid-air exchange.” Am J Ophthalmol 124, no. 5 (November 1997): 692–93. https://doi.org/10.1016/s0002-9394(14)70911-0.Full Text Link to Item
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Liu, N. P., W. L. Roberts, L. P. Hale, M. C. Levesque, D. D. Patel, C. L. Lu, and G. J. Jaffe. “Expression of CD44 and variant isoforms in cultured human retinal pigment epithelial cells.” Invest Ophthalmol Vis Sci 38, no. 10 (September 1997): 2027–37.Link to Item
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Merrill, P. T., J. Kim, T. A. Cox, C. C. Betor, R. M. McCallum, and G. J. Jaffe. “Uveitis in the southeastern United States.” Curr Eye Res 16, no. 9 (September 1997): 865–74. https://doi.org/10.1076/ceyr.16.9.865.5048.Full Text Link to Item
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Hainsworth, D. P., M. W. Johnson, and G. J. Jaffe. “Sustained closure of surgically repaired macular holes after retinal detachment with submacular fluid.” Am J Ophthalmol 123, no. 3 (March 1997): 364–69. https://doi.org/10.1016/s0002-9394(14)70132-1.Full Text Link to Item
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Arroyo, J. G., and G. J. Jaffe. “Spontaneous giant retinal pigment epithelial tear associated with panuveitis.” Retina 17, no. 3 (1997): 254–56. https://doi.org/10.1097/00006982-199705000-00014.Full Text Link to Item
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Johnson, M. W., G. M. Greven, G. J. Jaffe, H. Sudhalkar, and A. K. Vine. “Atypical, severe toxoplasmic retinochoroiditis in elderly patients.” Ophthalmology 104, no. 1 (January 1997): 48–57. https://doi.org/10.1016/s0161-6420(97)30362-5.Full Text Link to Item
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Berger, A. S., C. K. Cheng, P. A. Pearson, P. Ashton, P. A. Crooks, T. Cynkowski, G. Cynkowska, and G. J. Jaffe. “Intravitreal sustained release corticosteroid-5-fluoruracil conjugate in the treatment of experimental proliferative vitreoretinopathy.” Invest Ophthalmol Vis Sci 37, no. 11 (October 1996): 2318–25.Link to Item
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Handa, J. T., A. Pearson, and G. J. Jaffe. “Clearance of antitransferrin receptor immunotoxin from the rabbit eye.” Curr Eye Res 15, no. 10 (October 1996): 1039–44. https://doi.org/10.3109/02713689609017653.Full Text Link to Item
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Hainsworth, D. P., S. N. Chen, T. A. Cox, and G. J. Jaffe. “Condensation on polymethylmethacrylate, acrylic polymer, and silicone intraocular lenses after fluid-air exchange in rabbits.” Ophthalmology 103, no. 9 (September 1996): 1410–18. https://doi.org/10.1016/s0161-6420(96)30490-9.Full Text Link to Item
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Rubin, P., C. Hulette, J. A. Khawly, M. Elkordy, A. Hussein, J. J. Vredenburgh, G. J. Jaffe, and W. P. Peters. “Ocular toxicity following high dose chemotherapy and autologous transplant.” Bone Marrow Transplant 18, no. 1 (July 1996): 253–56.Link to Item
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Handa, J. T., M. A. Keithahn, and G. J. Jaffe. “Transferrin-ricin A chain toxin limits the development of experimental proliferative vitreoretinopathy.” Exp Eye Res 62, no. 6 (June 1996): 689–96. https://doi.org/10.1006/exer.1996.0079.Full Text Link to Item
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Enyedi, L. B., P. A. Pearson, P. Ashton, and G. J. Jaffe. “An intravitreal device providing sustained release of cyclosporine and dexamethasone.” Curr Eye Res 15, no. 5 (May 1996): 549–57. https://doi.org/10.3109/02713689609000766.Full Text Link to Item
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Pearson, P. A., G. J. Jaffe, D. F. Martin, G. J. Cordahi, H. Grossniklaus, E. T. Schmeisser, and P. Ashton. “Evaluation of a delivery system providing long-term release of cyclosporine.” Arch Ophthalmol 114, no. 3 (March 1996): 311–17. https://doi.org/10.1001/archopht.1996.01100130307014.Full Text Link to Item
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MacCumber, M. W., B. W. McCuen, C. A. Toth, P. J. Ferrone, and G. J. Jaffe. “Tissue plasminogen activator for preserving inferior peripheral iridectomy patency in eyes with silicone oil.” Ophthalmology 103, no. 2 (February 1996): 269–73. https://doi.org/10.1016/s0161-6420(96)30705-7.Full Text Link to Item
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Handa, J. T., B. A. Berkowitz, C. A. Wilson, N. Ando, H. A. Sen, and G. J. Jaffe. “Hypoxia precedes the development of experimental preretinal neovascularization.” Graefes Arch Clin Exp Ophthalmol 234, no. 1 (January 1996): 43–46. https://doi.org/10.1007/BF00186517.Full Text Link to Item
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Khawly, J. A., P. Rubin, W. Petros, W. P. Peters, and G. J. Jaffe. “Retinopathy and optic neuropathy in bone marrow transplantation for breast cancer.” Ophthalmology 103, no. 1 (January 1996): 87–95. https://doi.org/10.1016/s0161-6420(96)30728-8.Full Text Link to Item
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MacCumber, M. W., G. J. Jaffe, and B. W. McCuen. “Treatment of migraine headache after ocular surgery with intravenous metoclopramide hydrochloride.” Am J Ophthalmol 121, no. 1 (January 1996): 96–97. https://doi.org/10.1016/s0002-9394(14)70542-2.Full Text Link to Item
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Nasir, M. A., and G. J. Jaffe. “Cytomegalovirus retinitis associated with Hodgkin's disease.” Retina 16, no. 4 (1996): 324–27. https://doi.org/10.1097/00006982-199616040-00008.Full Text Link to Item
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Elner, S. G., V. M. Elner, G. J. Jaffe, A. Stuart, S. L. Kunkel, and R. M. Strieter. “Cytokines in proliferative diabetic retinopathy and proliferative vitreoretinopathy.” Curr Eye Res 14, no. 11 (November 1995): 1045–53. https://doi.org/10.3109/02713689508998529.Full Text Link to Item
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Eaton, A. M., G. J. Jaffe, B. W. McCuen, and G. J. Mincey. “Condensation on the posterior surface of silicone intraocular lenses during fluid-air exchange.” Ophthalmology 102, no. 5 (May 1995): 733–36. https://doi.org/10.1016/s0161-6420(95)30961-x.Full Text Link to Item
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Jaffe, G. J., W. L. Roberts, H. L. Wong, A. D. Yurochko, and G. J. Cianciolo. “Monocyte-induced cytokine expression in cultured human retinal pigment epithelial cells.” Exp Eye Res 60, no. 5 (May 1995): 533–43. https://doi.org/10.1016/s0014-4835(05)80068-5.Full Text Link to Item
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Moroi-Fetters, S. E., O. Earley, A. Hirakata, M. G. Caron, and G. J. Jaffe. “Binding, coupling, and mRNA subtype heterogeneity of alpha 1-adrenergic receptors in cultured human RPE.” Exp Eye Res 60, no. 5 (May 1995): 527–32. https://doi.org/10.1016/s0014-4835(05)80067-3.Full Text Link to Item
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Cheng, C. K., A. S. Berger, P. A. Pearson, P. Ashton, and G. J. Jaffe. “Intravitreal sustained-release dexamethasone device in the treatment of experimental uveitis.” Invest Ophthalmol Vis Sci 36, no. 2 (February 1995): 442–53.Link to Item
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Eaton, A. M., B. W. McCuen, G. J. Jaffe, and G. J. Mincey. “Authors' reply.” Ophthalmology 102, no. 10 (January 1, 1995): 1413. https://doi.org/10.1016/S0161-6420(13)30855-0.Full Text
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Melberg, N. S., D. F. Williams, M. W. Balles, G. J. Jaffe, T. A. Meredith, S. R. Sneed, and D. J. Westrich. “Vitrectomy for vitreomacular traction syndrome with macular detachment.” Retina 15, no. 3 (1995): 192–97. https://doi.org/10.1097/00006982-199515030-00002.Full Text Link to Item
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Pendergast, S. D., D. F. Martin, A. D. Proia, G. J. Jaffe, and B. W. McCuen. “Removal of optic disc stalks during diabetic vitrectomy.” Retina 15, no. 1 (1995): 25–28. https://doi.org/10.1097/00006982-199515010-00005.Full Text Link to Item
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Goins, K. M., J. R. Ortiz, S. F. Fulcher, J. T. Handa, G. J. Jaffe, G. N. Foulks, and L. M. Cobo. “Inhibition of proliferating lens epithelium with antitransferrin receptor immunotoxin.” J Cataract Refract Surg 20, no. 5 (September 1994): 513–16. https://doi.org/10.1016/s0886-3350(13)80230-1.Full Text Link to Item
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Jaffe, G. J., C. E. Harrison, G. M. Lui, W. L. Roberts, P. C. Goldsmith, S. Mesiano, and R. B. Jaffe. “Activin expression by cultured human retinal pigment epithelial cells.” Invest Ophthalmol Vis Sci 35, no. 7 (June 1994): 2924–31.Link to Item
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Martin, D. F., C. C. Awh, B. W. McCuen, G. J. Jaffe, J. H. Slott, and R. Machemer. “Treatment and pathogenesis of traumatic chorioretinal rupture (sclopetaria).” Am J Ophthalmol 117, no. 2 (February 15, 1994): 190–200. https://doi.org/10.1016/s0002-9394(14)73076-4.Full Text Link to Item
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Handa, J. T., S. Murad, and G. J. Jaffe. “Inhibition of cultured human RPE cell proliferation and lysyl hydroxylase activity by hydroxy derivatives of minoxidil.” Invest Ophthalmol Vis Sci 35, no. 2 (February 1994): 463–69.Link to Item
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Ashton, P., D. L. Blandford, P. A. Pearson, G. J. Jaffe, D. F. Martin, and R. B. Nussenblatt. “Review: implants.” J Ocul Pharmacol 10, no. 4 (1994): 691–701. https://doi.org/10.1089/jop.1994.10.691.Full Text Link to Item
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Han, D. P., Q. Wang, A. Hartz, G. J. Jaffe, T. G. Murray, H. C. Boldt, E. L. Arrindell, E. Coe, G. W. Abrams, and W. F. Mieler. “Postoperative fibrin formation and visual outcome after pars plana vitrectomy.” Retina 14, no. 3 (1994): 225–30. https://doi.org/10.1097/00006982-199414030-00007.Full Text Link to Item
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Handa, J. T., and G. J. Jaffe. “Lightning maculopathy. A case report.” Retina 14, no. 2 (1994): 169–72.Link to Item
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Shattuck, R. L., L. D. Wood, G. J. Jaffe, and A. Richmond. “MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells.” Mol Cell Biol 14, no. 1 (January 1994): 791–802. https://doi.org/10.1128/mcb.14.1.791-802.1994.Full Text Link to Item
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Handa, J. T., L. L. Houston, and G. J. Jaffe. “The antiproliferative effect of a transferrin-toxin on human retinal pigment epithelial cells and rabbit fibroblasts.” Invest Ophthalmol Vis Sci 34, no. 12 (November 1993): 3419–28.Link to Item
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Jaffe, G. J., A. Richmond, L. Van Le, R. L. Shattuck, Q. C. Cheng, F. Wong, and W. Roberts. “Expression of three forms of melanoma growth stimulating activity (MGSA)/gro in human retinal pigment epithelial cells.” Invest Ophthalmol Vis Sci 34, no. 9 (August 1993): 2776–85.Link to Item
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Jaffe, G. J., and D. Hickingbotham. “An illuminated cannula for subretinal operations.” Am J Ophthalmol 115, no. 6 (June 15, 1993): 816–17. https://doi.org/10.1016/s0002-9394(14)73656-6.Full Text Link to Item
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Jaffe, G. J. “Cataract extraction in the diabetic patient.” Semin Ophthalmol 8, no. 2 (June 1993): 79–86. https://doi.org/10.3109/08820539309060214.Full Text Link to Item
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Handa, J. T., S. Murad, and G. J. Jaffe. “Minoxidil inhibits ocular cell proliferation and lysyl hydroxylase activity.” Invest Ophthalmol Vis Sci 34, no. 3 (March 1993): 567–75.Link to Item
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Jaffe, G. J. “Diagnostic vitrectomy in the management of ocular disease.” Semin Ophthalmol 8, no. 1 (March 1993): 15–23. https://doi.org/10.3109/08820539309060206.Full Text Link to Item
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Handa, J. T., L. L. Houston, and G. J. Jaffe. “Monensin enhances the cytotoxic effect of antitransferrin receptor immunotoxin on cultured RPE cells.” Curr Eye Res 12, no. 1 (January 1993): 45–53. https://doi.org/10.3109/02713689308999495.Full Text Link to Item
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Arrindell, E. L., B. S. McKay, G. J. Jaffe, and J. M. Burke. “Modulation of potassium transport in cultured retinal pigment epithelium and retinal glial cells by serum and epidermal growth factor.” Exp Cell Res 203, no. 1 (November 1992): 192–97. https://doi.org/10.1016/0014-4827(92)90055-d.Full Text Link to Item
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Jaffe, G. J., T. C. Burton, E. Kuhn, A. Prescott, and A. Hartz. “Progression of nonproliferative diabetic retinopathy and visual outcome after extracapsular cataract extraction and intraocular lens implantation.” Am J Ophthalmol 114, no. 4 (October 15, 1992): 448–56. https://doi.org/10.1016/s0002-9394(14)71857-4.Full Text Link to Item
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Fulcher, S. F., G. N. Foulks, M. Wilkerson, L. M. Cobo, G. J. Jaffe, and D. L. Hatchell. “Inhibition of human corneal epithelium with immunotoxin 454A12-rRA.” Cornea 11, no. 5 (September 1992): 413–17. https://doi.org/10.1097/00003226-199209000-00010.Full Text Link to Item
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Jaffe, G. J., L. Van Le, F. Valea, S. Haskill, W. Roberts, W. P. Arend, A. Stuart, and W. P. Peters. “Expression of interleukin-1 alpha, interleukin-1 beta, and an interleukin-1 receptor antagonist in human retinal pigment epithelial cells.” Exp Eye Res 55, no. 2 (August 1992): 325–35. https://doi.org/10.1016/0014-4835(92)90197-z.Full Text Link to Item
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“Vitrectomy with silicone oil or sulfur hexafluoride gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 1.” Arch Ophthalmol 110, no. 6 (June 1992): 770–79. https://doi.org/10.1001/archopht.1992.01080180042027.Full Text Link to Item
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“Vitrectomy with silicone oil or perfluoropropane gas in eyes with severe proliferative vitreoretinopathy: results of a randomized clinical trial. Silicone Study Report 2.” Arch Ophthalmol 110, no. 6 (June 1992): 780–92. https://doi.org/10.1001/archopht.1992.01080180052028.Full Text Link to Item
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Jaffe, G. J., W. P. Peters, W. Roberts, J. Kurtzberg, A. Stuart, A. M. Wang, and J. B. Stoudemire. “Modulation of macrophage colony stimulating factor in cultured human retinal pigment epithelial cells.” Exp Eye Res 54, no. 4 (April 1992): 595–603. https://doi.org/10.1016/0014-4835(92)90138-i.Full Text Link to Item
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Murray, T. G., G. J. Jaffe, B. S. McKay, D. P. Han, J. M. Burke, and G. W. Abrams. “Collagen shield delivery of tissue plasminogen activator: functional and pharmacokinetic studies of anterior segment delivery.” Refract Corneal Surg 8, no. 1 (1992): 44–48.Link to Item
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Van Le, L., S. Haskill, G. J. Jaffe, and W. C. Fowler. “Expression of interleukin-1 and interleukin-1 receptor antagonists in endometrial cancer.” Gynecol Oncol 42, no. 2 (August 1991): 161–64. https://doi.org/10.1016/0090-8258(91)90338-6.Full Text Link to Item
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Burke, J. M., B. S. McKay, and G. J. Jaffe. “Retinal pigment epithelial cells of the posterior pole have fewer Na/K adenosine triphosphatase pumps than peripheral cells.” Invest Ophthalmol Vis Sci 32, no. 7 (June 1991): 2042–46.Link to Item
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Burke, J. M., G. J. Jaffe, and C. M. Brzeski. “The effect of culture density and proliferation rate on the expression of ouabain-sensitive Na/K ATPase pumps in cultured human retinal pigment epithelium.” Exp Cell Res 194, no. 2 (June 1991): 190–94. https://doi.org/10.1016/0014-4827(91)90353-v.Full Text Link to Item
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Haskill, S., G. Martin, L. Van Le, J. Morris, A. Peace, C. F. Bigler, G. J. Jaffe, C. Hammerberg, S. A. Sporn, and S. Fong. “cDNA cloning of an intracellular form of the human interleukin 1 receptor antagonist associated with epithelium.” Proc Natl Acad Sci U S A 88, no. 9 (May 1, 1991): 3681–85. https://doi.org/10.1073/pnas.88.9.3681.Full Text Link to Item
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Jaffe, G. J., S. Fulcher, and L. L. Houston. “Transferrin Receptor Expression by Retinal Pigment Epithelial Cells in Proliferative Vitreoretinopathy-Reply.” Archives of Ophthalmology 109, no. 9 (January 1, 1991): 1196. https://doi.org/10.1001/archopht.1991.01080090017008.Full Text
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Jaffe, G. J., K. Earnest, S. Fulcher, G. M. Lui, and L. L. Houston. “Antitransferrin receptor immunotoxin inhibits proliferating human retinal pigment epithelial cells.” Arch Ophthalmol 108, no. 8 (August 1990): 1163–68. https://doi.org/10.1001/archopht.1990.01070100119046.Full Text Link to Item
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Jaffe, G. J., D. Schwartz, D. P. Han, M. Gottlieb, A. Hartz, D. McCarty, W. F. Mieler, and G. W. Abrams. “Risk factors for postvitrectomy fibrin formation.” Am J Ophthalmol 109, no. 6 (June 15, 1990): 661–67. https://doi.org/10.1016/s0002-9394(14)72434-1.Full Text Link to Item
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Williams, D. F., S. R. Bennett, G. W. Abrams, D. P. Han, W. F. Mieler, G. J. Jaffe, and G. A. Williams. “Low-dose intraocular tissue plasminogen activator for treatment of postvitrectomy fibrin formation.” Am J Ophthalmol 109, no. 5 (May 15, 1990): 606–7. https://doi.org/10.1016/s0002-9394(14)70700-7.Full Text Link to Item
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Koenig, S. B., D. P. Han, W. F. Mieler, G. W. Abrams, G. J. Jaffe, and T. C. Burton. “Combined phacoemulsification and pars plana vitrectomy.” Arch Ophthalmol 108, no. 3 (March 1990): 362–64. https://doi.org/10.1001/archopht.1990.01070050060031.Full Text Link to Item
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Jaffe, G. J., G. W. Abrams, G. A. Williams, and D. P. Han. “Tissue plasminogen activator for postvitrectomy fibrin formation.” Ophthalmology 97, no. 2 (February 1990): 184–89. https://doi.org/10.1016/s0161-6420(90)32618-0.Full Text Link to Item
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Williams, D. F., W. F. Mieler, G. J. Jaffe, D. M. Robertson, and L. Hendrix. “Magnetic resonance imaging of juxtapapillary plaques in cadaver eyes.” Br J Ophthalmol 74, no. 1 (January 1990): 43–46. https://doi.org/10.1136/bjo.74.1.43.Full Text Link to Item
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Mieler, W. F., G. J. Jaffe, and R. A. Steeves. “Ferromagnetic hyperthermia and iodine 125 brachytherapy in the treatment of choroidal melanoma in a rabbit model.” Arch Ophthalmol 107, no. 10 (October 1989): 1524–28. https://doi.org/10.1001/archopht.1989.01070020598048.Full Text Link to Item
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Jaffe, G. J., H. Lewis, D. P. Han, G. A. Williams, and G. W. Abrams. “Treatment of postvitrectomy fibrin pupillary block with tissue plasminogen activator.” Am J Ophthalmol 108, no. 2 (August 15, 1989): 170–75. https://doi.org/10.1016/0002-9394(89)90013-5.Full Text Link to Item
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Jaffe, G. J., W. F. Mieler, R. L. Radius, M. C. Kincaid, B. M. Massaro, and G. W. Abrams. “Ab interno sclerostomy with a high-powered argon endolaser. Clinicopathologic correlation.” Arch Ophthalmol 107, no. 8 (August 1989): 1183–85. https://doi.org/10.1001/archopht.1989.01070020249034.Full Text Link to Item
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Jaffe, G. J., G. D. Green, and G. W. Abrams. “Stability of recombinant tissue plasminogen activator.” Am J Ophthalmol 108, no. 1 (July 15, 1989): 90–91. https://doi.org/10.1016/s0002-9394(14)73272-6.Full Text Link to Item
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Irvine, A. R., and G. Jaffe. “Authors' reply.” Ophthalmology 96, no. 6 (January 1, 1989): 926. https://doi.org/10.1016/S0161-6420(89)38015-8.Full Text
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Jaffe, G. J., J. M. Burke, and D. H. Geroski. “Ouabain-sensitive Na+-K+ ATPase pumps in cultured human retinal pigment epithelium.” Exp Eye Res 48, no. 1 (January 1989): 61–68. https://doi.org/10.1016/0014-4835(89)90019-5.Full Text Link to Item
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Jaffe, G. J., W. F. Mieler, J. M. Burke, and G. A. Williams. “Photoablation of ocular melanoma with a high-powered argon endolaser.” Arch Ophthalmol 107, no. 1 (January 1989): 113–18. https://doi.org/10.1001/archopht.1989.01070010115038.Full Text Link to Item
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Ortiz, J. R., S. D. Walker, P. E. McManus, L. A. Martinez, R. H. Brown, and G. J. Jaffe. “Filtering bleb thrombolysis with tissue plasminogen activator.” Am J Ophthalmol 106, no. 5 (November 15, 1988): 624–25. https://doi.org/10.1016/0002-9394(88)90598-3.Full Text Link to Item
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Jaffe, G. J., G. A. Williams, W. F. Mieler, and R. L. Radius. “Ab interno sclerostomy with a high-powered argon endolaser.” Am J Ophthalmol 106, no. 4 (October 15, 1988): 391–96. https://doi.org/10.1016/0002-9394(88)90872-0.Full Text Link to Item
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Williams, G. A., F. H. Lambrou, G. A. Jaffe, R. W. Snyder, G. D. Green, R. G. Devenyi, and G. W. Abrams. “Treatment of postvitrectomy fibrin formation with intraocular tissue plasminogen activator.” Arch Ophthalmol 106, no. 8 (August 1988): 1055–58. https://doi.org/10.1001/archopht.1988.01060140211025.Full Text Link to Item
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Jaffe, G. J., A. R. Irvine, I. S. Wood, J. W. Severinghaus, G. R. Pino, and C. Haugen. “Retinal phototoxicity from the operating microscope. The role of inspired oxygen.” Ophthalmology 95, no. 8 (August 1988): 1130–41. https://doi.org/10.1016/s0161-6420(88)33065-4.Full Text Link to Item
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Jaffe, G. J., G. D. Green, B. S. McKay, A. Hartz, and G. A. Williams. “Intravitreal clearance of tissue plasminogen activator in the rabbit.” Arch Ophthalmol 106, no. 7 (July 1988): 969–72. https://doi.org/10.1001/archopht.1988.01060140115036.Full Text Link to Item
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Jaffe, G. J., and H. Schatz. “Histopathologic features of adult-onset foveomacular pigment epithelial dystrophy.” Arch Ophthalmol 106, no. 7 (July 1988): 958–60. https://doi.org/10.1001/archopht.1988.01060140104034.Full Text Link to Item
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Jaffe, G. J., and T. C. Burton. “Progression of nonproliferative diabetic retinopathy following cataract extraction.” Arch Ophthalmol 106, no. 6 (June 1988): 745–49. https://doi.org/10.1001/archopht.1988.01060130815029.Full Text Link to Item
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Jaffe, G., and H. Schatz. “Ocular manifestations of preeclampsia.” Am J Ophthalmol 103, no. 3 Pt 1 (March 15, 1987): 309–15.Link to Item
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Jaffe, G. J., and W. H. Stern. “Pale-centered retinal hemorrhages following vitrectomy. Case report.” Arch Ophthalmol 105, no. 1 (January 1987): 25–26. https://doi.org/10.1001/archopht.1987.01060010031016.Full Text Link to Item
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Jaffe, G. J., J. P. Whitcher, R. Biswell, and A. R. Irvine. “Propionibacterium acnes endophthalmitis seven months after extracapsular cataract extraction and intraocular lens implantation.” Ophthalmic Surg 17, no. 12 (December 1986): 791–93.Link to Item
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Jaffe, G. J., J. A. Alvarado, and R. P. Juster. “Age-related changes of the normal visual field.” Arch Ophthalmol 104, no. 7 (July 1986): 1021–25. https://doi.org/10.1001/archopht.1986.01050190079043.Full Text Link to Item
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Book Sections
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Lin, P., and G. J. Jaffe. “Intermediate uveitis.” In Retina Fifth Edition, 1405–14, 2012. https://doi.org/10.1016/B978-1-4557-0737-9.00079-5.Full Text
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Cahill, M. T., and G. J. Jaffe. “Nondegradable intraocular sustained-release drug delivery devices.” In Intraocular Drug Delivery, 203–26, 2006.
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Cahill, M. T., and G. J. Jaffe. “Intraocular sustained-release drug delivery in Uveitis.” In Intraocular Drug Delivery, 265–78, 2006.
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Phillips, S. J., and G. J. Jaffe. “Drug delivery for proliferative vitreoretinopathy: Prevention and treatment.” In Intraocular Drug Delivery, 279–90, 2006.
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Park, C. H., and G. J. Jaffe. “Steroids in Macular Disease.” In Retina: Fourth Edition, 2–3:979–90, 2005. https://doi.org/10.1016/B978-0-323-02598-0.50061-6.Full Text
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Other Articles
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Jaffe, G. J. “Normative databases for SD-OCT: Only part of the story: Databases have their place, but individual serial measurements are the gold standard for tracking disease.” Retina Today, September 1, 2012.
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Jaffe, G. J., and J. D. Palmer. “AMD and imaging.” Retina Today, March 1, 2012.
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Jaffe, G. J. “CNTF-secreting implant for geographic atrophy: Eighteen-month results show device to be well-tolerated with no serious adverse events.” Retina Today, October 1, 2010.
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Jaffe, G. J. “Sustained drug-delivery for retinal disease: Current technologies include implanted and injected devices.” Retina Today, May 1, 2010.
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Jaffe, G. J. “CNTF-secreting implant for dry AMD: Phase 2 trial in patients with geographic atrophy shows safety, potential therapeutic effect.” Retina Today, October 1, 2009.
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Goldstein, D. A., D. G. Godfrey, A. Hall, D. G. Callanan, G. J. Jaffe, P. A. Pearson, D. W. Usner, and T. L. Comstock. “In reply.” Archives of Ophthalmology, January 1, 2009. https://doi.org/10.1001/archophthalmol.2008.555.Full Text
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Hee, Michael R. “Automated measurements of retinal thickness with optical coherence tomography.” Am J Ophthalmol, August 2005. https://doi.org/10.1016/j.ajo.2005.02.062.Full Text Link to Item
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Kwong, Yolanda Y. Y., Wico W. Lai, and Dennis S. C. Lam. “Intravitreal triamcinolone acetonide in eyes with cystoid macular edema associated with central retinal vein occlusion.” Am J Ophthalmol, March 2004. https://doi.org/10.1016/j.ajo.2003.11.052.Full Text Link to Item
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Park, Carl H., Glenn J. Jaffe, and Sharon Fekrat. “Author reply.” American Journal of Ophthalmology. Elsevier BV, March 2004. https://doi.org/10.1016/j.ajo.2003.11.063.Full Text
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Park, Carl H., Glenn J. Jaffe, and Sharon Fekrat. “Author reply.” American Journal of Ophthalmology. Elsevier BV, March 2004. https://doi.org/10.1016/j.ajo.2003.11.054.Full Text
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McDonald, H. R. “Diagnostic and therapeutic challenges.” Retina, 2001. https://doi.org/10.1097/00006982-200102000-00011.Full Text Link to Item
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Theodosiadis, P., I. Vergados, N. Markomichelakis, I. Ladas, and A. Skandali. “Retinopathy and optic neuropathy after transplantation.” Ophthalmology, February 1997. https://doi.org/10.1016/s0161-6420(97)38998-2.Full Text Link to Item
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Shattuck, R. L., L. D. Wood, G. J. Jaffe, and A. Richmond. “Erratum: MGSA/GRO transcription is differentially regulated in normal retinal pigment epithelial and melanoma cells (Molecular and Cellular Biology 14:1 (795)).” Molecular and Cellular Biology, January 1, 1995.
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Pearson, P. A., G. J. Jaffe, and P. Ashton. “Intravitreal foscarnet for cytomegalovirus retinitis in a patient with acquired immunodeficiency syndrome.” Am J Ophthalmol, May 15, 1993. https://doi.org/10.1016/s0002-9394(14)71487-4.Full Text Link to Item
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Avery, R. L., D. Hickingbotham, G. Jaffe, and E. de Juan. “Intraoperative fluorescein angioscopy in subretinal surgery.” Arch Ophthalmol, November 1992. https://doi.org/10.1001/archopht.1992.01080230016006.Full Text Link to Item
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Baudouin, C., F. Brignole, P. Gastaud, G. J. Jaffe, S. Fulcher, and L. L. Houston. “Transferrin receptor expression by retinal pigment epithelial cells in proliferative vitreoretinopathy [4].” Archives of Ophthalmology, 1991.
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Jaffe, G. “Control of subretinal fluid: Experimental and clinical studies. by M.F. Marmor. Eye 4:340-344, 1990.” Survey of Ophthalmology, January 1, 1990. https://doi.org/10.1016/0039-6257(90)90096-e.Full Text
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Jaffe, G. “Medical conditions underlying retinal vein occlusion in patients with glaucoma or ocular hypertension: Comment.” Survey of Ophthalmology, 1990. https://doi.org/10.1016/0039-6257(90)90135-I.Full Text
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Jaffe, G. “New hypotheses on the pathogenesis and treatment of serous retinal detachment. by M.F. Marmor. Graefe's Arch Clin Exp Ophthalmol 226:548-552, 1988.” Survey of Ophthalmology, January 1, 1989. https://doi.org/10.1016/0039-6257(89)90137-9.Full Text
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Jaffe, G. J., and I. S. Wood. “Retinal phototoxicity from the operating microscope: a protective effect by the fovea.” Arch Ophthalmol, April 1988. https://doi.org/10.1001/archopht.1988.01060130487004.Full Text Link to Item
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Conference Papers
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Dugel, Pravin U., Rishi P. Singh, Adrian Koh, Yuichiro Ogura, Georges Weissgerber, Kinfemichael Gedif, Glenn J. Jaffe, Ramin Tadayoni, Ursula Schmidt-Erfurth, and Frank G. Holz. “HAWK and HARRIER: Ninety-Six-Week Outcomes from the Phase 3 Trials of Brolucizumab for Neovascular Age-Related Macular Degeneration.” In Ophthalmology, 128:89–99, 2021. https://doi.org/10.1016/j.ophtha.2020.06.028.Full Text Link to Item
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Schneider, Eric W., and Glenn J. Jaffe. “BASELINE CHARACTERISTICS OF VITREOMACULAR TRACTION PROGRESSING TO FULL-THICKNESS MACULAR OR LAMELLAR HOLES IN THE PHASE III TRIALS OF ENZYMATIC VITREOLYSIS.” In Retina, 40:1579–84, 2020. https://doi.org/10.1097/IAE.0000000000002634.Full Text Link to Item
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Jaffe, Glenn J. “Treatment of non-infectious uveitis that affects the posterior segment with a single intravitreal fluocinolone acetonide insert (FAi)-3-year results.” In Investigative Ophthalmology & Visual Science, Vol. 60. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2019.Link to Item
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Loo, Jessica, Traci E. Clemons, Emily Y. Chew, Martin Friedlander, Glenn J. Jaffe, and Sina Farsiu. “Automatic Deep Learning OCT Analysis Algorithm Reliably Reproduces Expert-Evaluated Outcome of a Randomized Clinical Trial for Macular Telangiectasia Type 2 Treatment.” In Investigative Ophthalmology & Visual Science, Vol. 60. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2019.Link to Item
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Umunakwe, Obi, Susan Wakil, Atalie C. Thompson, Glenn J. Jaffe, Terry Kim, and Leon Herndon. “Clinical outcomes following the triple procedure.” In Investigative Ophthalmology & Visual Science, Vol. 60. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2019.Link to Item
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Yang, Ping, Samantha Erin Neal, and Glenn J. Jaffe. “Luminate protects against hydroquinone-induced injury in human RPE cells.” In Investigative Ophthalmology & Visual Science, Vol. 60. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2019.Link to Item
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Jaffe, Glenn J., Gui-Shuang Ying, Cynthia A. Toth, Ebenezer Daniel, Juan E. Grunwald, Daniel F. Martin, Maureen G. Maguire, and Maureen G. Comparison of Age-related Macular Degeneration Treatments Trials Research Group. “Macular Morphology and Visual Acuity in Year Five of the Comparison of Age-related Macular Degeneration Treatments Trials.” In Ophthalmology, 126:252–60, 2019. https://doi.org/10.1016/j.ophtha.2018.08.035.Full Text Link to Item
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Chew, Emily Y., Traci E. Clemons, Glenn J. Jaffe, Sina Farsiu, Eleonora Lad, and Martin Friedlander. “Phase 2 Trial of Ciliary Neurotrophic Factor for Macular Telangiectasia Type 2.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Clemons, Traci E., Emily Y. Chew, Eleonora M. Lad, Glenn J. Jaffe, Sina Farsiu, Sarah Duwel, David Cunefare, and Dibyendu Mukherji. “Longitudinal Structure/Function Correlation Between Microperimetry and OCT Imaging in Type 2 Macular Telangiectasia (MacTel).” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Daniel, Ebenezer, Benjamin J. Kim, Wei Pan, Juan E. Grunwald, Gui-Shuang Ying, Cynthia A. Toth, Glenn J. Jaffe, Daniel F. Martin, and Maureen G. Maguire. “Long term Follow up of non-fibrotic scars in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT).” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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DeSouza, Philip, Scott Walter, David Cunefare, Rajiv Shah, Sina Farsiu, and Glenn J. Jaffe. “Semi-Automated Segmentation of Hyperreflective Foci on Optical Coherence Tomography.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Jaffe, Glenn J., Adrian H. C. Koh, Yuichiro Ogura, Andreas Weichselberger, Frank G. Holz, and Pravin U. Dugel. “Phase III studies of brolucizumab versus aflibercept in nAMD: 48-week primary and key secondary outcomes from HAWK/HARRIER.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Loo, Jessica, Leyuan Fang, David Cunefare, Glenn J. Jaffe, and Sina Farsiu. “Deep learning-based automatic segmentation of ellipsoid zone defects in optical coherence tomography images of macular telangiectasia type 2.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Sugar, Elizabeth A., Janet A. Holbrook, Alyce E. Burke, Glenn J. Jaffe, Albert T. Vitale, Janet L. Davis, and Douglas A. Jabs. “Dissociations of the fluocinolone acetonide implant: experience from long-term follow-up during the Multicenter Uveitis Steroid Treatment (MUST) Trial and Follow-up Study.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Yang, Ping, Grace M. Tewkesbury, Kristen L. Buehne, Jae Yang, Peter Baciu, and Glenn J. Jaffe. “Effect of Tec Kinases Inhibitor on Complement-mediated Release of Basic Fibroblast Growth Factor from Human RPE Cells.” In Investigative Ophthalmology & Visual Science, Vol. 59. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2018.Link to Item
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Abu-Rmaileh, Muhammad Akef, Victoria Treboschi, Ping Yang, and Glenn J. Jaffe. “Effect of Bax Inhibitor 1 overexpression on Tunicamycin-induced ER Stress in Human RPE Cells.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Daniel, Ebenezer, Juan E. Grunwald, Maureen G. Maguire, Wei Pan, Cynthia A. Toth, Glenn Jay Jaffe, Daniel F. Martin, and Gui-Shuang Ying. “Risk factors for retinal scar development in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT).” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Finn, Avni P., Akshay Thomas, Dilraj Singh Grewal, and Glenn Jay Jaffe. “Cystoid Macular Edema as a Marker in the Progression of Autoimmune Retinopathy.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Jaffe, Glenn J., Dario Paggiarino, and Gerald Riedel. “An Injectable Fluocinolone Acetonide Intravitreal Insert Decreases the Incidence of Recurrence in Patients with Chronic Non-infectious Uveitis Affecting the Posterior Segment of the Eye: 12 Month Results.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Maguire, Maureen G., Wei Pan, Juan E. Grunwald, Ebenezer Daniel, Glenn Jay Jaffe, Cynthia A. Toth, Stephanie A. Hagstrom, Gui-Shuang Ying, and Daniel F. Martin. “Incidence and risk factors for neovascular AMD in the fellow eye in the Comparison of AMD Treatment Trials (GATT) Follow-up Study.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Martin, Daniel F., Stuart L. Fine, Wei Pan, Juan E. Grunwald, Ebenezer Daniel, Glenn J. Jaffe, Cynthia A. Toth, Gui-Shuang Ying, and Maureen G. Maguire. “Characteristics of Patients with Good Visual Acuity at 5 Years Despite No Treatment after 2 Years in the Comparison of AMID Treatment Trials (CATT) Follow-up Study.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Tai, Vincent, Stephanie Chiu, Katrina Winter, Ebenezer Daniel, Juan E. Grunwald, Maxwell Pistilli, Monica Sevilla, et al. “Linking optical coherence tomographic, angiographic and photographic lesion components in neovascular age-related macular degeneration in the Comparison of Age-related Macular Degeneration Treatments Trials.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Toth, Cynthia A., Vincent Tai, Maxwell Pistilli, Stephanie Chiu, Katrina Winter, Ebenezer Daniel, Juan E. Grunwald, et al. “Distribution of optical coherence tomographic morphologic components within areas appearing as atrophic or scarred after two years of anti-VEGF treatment for neovascular age-related macular degeneration in the Comparison of Age-related Macular Degeneration Treatments Trials.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Yang, Ping, Muhammad Abu-Rmaileh, Peter Baciu, and Glenn J. Jaffe. “Complement Membrane Attack Complex Release Basic Fibroblast Growth Factor from Human RPE Cells.” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Ying, Gui-Shuang, Maureen G. Maguire, Wei Pan, Juan E. Grunwald, Ebenezer Daniel, Glenn J. Jaffe, Cynthia A. Toth, and Daniel F. Martin. “Baseline Predictors of Five-Year Visual Acuity in the Comparison of AMD Treatment Trials (CATT).” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Zhang, Wenlan, Gui-Shuang Ying, Daniel F. Martin, Maureen G. Maguire, Cynthia A. Toth, and Glenn J. Jaffe. “Associations of retinal and choroidal thickness with visual acuity at year 5 in the Comparison of Age-Related Macular Degeneration Treatment Trials (GATT).” In Investigative Ophthalmology & Visual Science, Vol. 58. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2017.Link to Item
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Heier, Jeffrey S., Jean-François Korobelnik, David M. Brown, Ursula Schmidt-Erfurth, Diana V. Do, Edoardo Midena, David S. Boyer, et al. “Intravitreal Aflibercept for Diabetic Macular Edema: 148-Week Results from the VISTA and VIVID Studies.” In Ophthalmology, 123:2376–85, 2016. https://doi.org/10.1016/j.ophtha.2016.07.032.Full Text Link to Item
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Suhler, Eric B., Glenn J. Jaffe, Quan Dong Nguyen, Antoine P. Brezin, Manfred Zierhut, Albert Vitale, Mirjam van Velthoven, et al. “Long-Term Safety and Efficacy of Adalimumab in Patients with Non-Infectious Intermediate, Posterior, or Panuveitis in an Ongoing Open-Label Study.” In Arthritis & Rheumatology, Vol. 68. WILEY, 2016.Link to Item
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Baciu, Peter, Jia-Ying Yang, Iona Raymond, Ping Yang, Victoria Treboschi, and Glenn J. Jaffe. “Combined Complement Deregulation and Oxidative Stress in SOD1/CD59a null Mice Develop AMD-like Phenotypes.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Brezin, Antoine P., Andrew D. Dick, Glenn J. Jaffe, Shigeaki Ohno, Kenichi Namba, Hiroshi Goto, Noritaka Inomata, et al. “Adalimumab in patients with active and inactive, non-infectious uveitis: VISUAL I and VISUAL II trials.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Ciulla, Thomas A., Glenn J. Jaffe, and Samir Patel. “Assessment of Retinal Pigment Epithelium (RPE) Atrophy in a Phase 2b Study of a Platelet Derived Growth Factor inhibitor (Fovista (R)), in combination with a Vascular Endothelial Growth Factor inhibitor (Ranibizumab) for Neovascular Age-Related Macular Degeneration (NAMD).” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Daniel, Ebenezer, Juan E. Grunwald, Benjamin J. Kim, Maureen G. Maguire, James A. Shaffer, Glenn J. Jaffe, Cynthia A. Toth, Daniel F. Martin, Frederick L. Ferris, and Gui-Shuang Ying. “Hard Exudates and Treatment Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT).” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Grunwald, Juan E., Maxwell Pistilli, Ebenezer Daniel, Gui-Shuang Ying, Glenn J. Jaffe, Stuart L. Fine, Daniel F. Martin, and Maureen G. Maguire. “Size and Growth of Geographic Atrophy During 5 Years of Follow Up in the Comparison of Age-related Macular Degeneration Treatments Trials (GATT).” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Lad, Eleonora M., Dibyendu Mukherjee, Ryan R. Vann, Traci E. Clemons, Emily Y. Chew, Glenn J. Jaffe, and Sina Farsiu. “Novel software to assess correlation between MAIA microperimetry and OCT imaging of ellipsoid zone in type 2 idiopathic macular telangiectasia.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Treboschi, Victoria, Zhe Ma, Grace Tewkesbury, Ping Yang, and Glenn J. Jaffe. “The Protective Effect of Bax Inhibitor 1 (BI-1) on Tunicamycin-induced Human RPE Cell Death.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Yang, Ping, Victoria Treboschi, Peter Baciu, and Glenn J. Jaffe. “The Association of Apolipoprotein E and Membrane Attack Complex in Human RPE Cell.” In Investigative Ophthalmology & Visual Science, Vol. 57. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2016.Link to Item
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Brezin, Antoine P., Phillippe Kestelyn, Joachim Van Calster, Glenn J. Jaffe, Jennifer E. Thorne, David Scales, Pablo Franco, et al. “Adalimumab in Patients with Active, Noninfectious Uveitis Using High-Dose Corticosteroids.” In Arthritis & Rheumatology, Vol. 67. WILEY-BLACKWELL, 2015.Link to Item
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Ciulla, Thomas A., Gui-Shuang Ying, Maureen G. Maguire, Daniel F. Martin, Glenn J. Jaffe, Juan E. Grunwald, Ebenezer Daniel, and Cynthia A. Toth. “Influence of the Vitreomacular Interface on Treatment Outcomes in the Comparison of AMD Treatments Trials (CATT).” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Daniel, Ebenezer, Maureen G. Maguire, James Shaffer, Gui-Shuang Ying, Juan E. Grunwald, Glenn J. Jaffe, and Daniel F. Martin. “Retinal Angiomatous Proliferation and Treatment Outcomes in the Comparison of Age-Related Macular Degeneration Treatments Trials (CATT).” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Jaffe, Glenn J., Jennifer E. Thorne, David Scales, Pablo Franco, Samir R. Tari, Anne Camez, Alexandra P. Song, Martina Kron, Talin Barisani-Asenbauer, and Andrew D. Dick. “Adalimumab in Patients With Active, Non-infectious Uveitis Requiring High-dose Corticosteroids: the VISUAL-1 Trial.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Munk, Marion Ronit, Lee M. Jampol, Christian Simader, Wolfgang Huf, Tamara Mittermueller, Glenn J. Jaffe, and Ursula Schmidt-Erfurth. “Automated, software based differentiation of diabetic macular edema from pseudophakic cystoid macular edema using SD-OCT.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Pistilli, Maxwell, Gui-Shuang Ying, Cynthia A. Toth, Glenn J. Jaffe, and Daniel F. Martin. “Resolution of Retinal Fluid on Optical Coherence Tomography in the Comparison of AMD Treatments Trials (CATT).” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Shah, Neepa, Maureen G. Maguire, Daniel F. Martin, James Shaffer, Gui-Shuang Ying, Juan E. Grunwald, Cynthia A. Toth, Glenn J. Jaffe, and Ebenezer Daniel. “Petaloid Macular Edema and Outcomes in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT).” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Wiley, Henry, Clare Bailey, Catherine A. Cukras, Glenn J. Jaffe, Richard W. J. Lee, Erin Loken, Catherine Meyerle, Darby J. S. Thompson, Wai T. Wong, and Frederick L. Ferris. “A randomized 36-week crossover trial comparing ranibizumab and bevacizumab for diabetic macular edema.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Willoughby, Alex, Gui-Shuang Ying, Maureen G. Maguire, Cynthia A. Toth, Russell Burns, Ebenezer Daniel, and Glenn J. Jaffe. “The Association of Subretinal Hyper-Reflective Material (SHRM) and Visual Acuity in the Comparison of Age-related Macular Degeneration Treatments Trials (CATT).” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Yang, Ping, Nikolai P. Skiba, Grace M. Tewkesbury, Peter Baciu, and Glenn J. Jaffe. “Complement-mediated Apolipoprotein E Accumulation in Cultured Human RPE Cell.” In Investigative Ophthalmology & Visual Science, Vol. 56. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2015.Link to Item
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Walsh, D. I., S. K. Murthy, P. S. Hahn, G. J. Jaffe, G. J. Sommer, and U. Y. Schaff. “Lab-on-a-disk immunoassay for ocular diagnostics.” In Proceedings of the Ieee Annual Northeast Bioengineering Conference, Nebec, Vol. 2014-December, 2014. https://doi.org/10.1109/NEBEC.2014.6972966.Full Text
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Bao, Michelle, Zhe Ma, Ping Yang, Peter Baciu, and Glenn J. Jaffe. “The Role of Nrf-2 in Alternative Pathway (AP) Complement and Hydroquinone (HQ)-mediated Heme Oxygenase-1 (HO1) Expression in Human RPE (hRPE) Cells.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Long, Angel, Michelle Bao, Ping Yang, and Glenn J. Jaffe. “Complement Attack by the Alternative Pathway Increases Gene Expression and Protein Expression of ER Stress Markers in Human RPE Cells.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Simader, Christian, Sebastian M. Waldstein, Michael Larsen, Paul Mitchell, Giovanni Staurenghi, Glenn J. Jaffe, and Ursula Schmidt-Erfurth. “Structure-function correlation of optical coherence tomography features and visual outcome in a fixed and a PRN regimen in neovascular AMD.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Yang, Ping, Nikolai P. Skiba, Michelle Bao, Angel Long, Peter Baciu, and Glenn J. Jaffe. “Proteomics Analysis of Protein Expression in Human RPE Cells Exposed to Oxidant and Complement Attack through Alternative Pathway.” In Investigative Ophthalmology & Visual Science, Vol. 55. ASSOC RESEARCH VISION OPHTHALMOLOGY INC, 2014.Link to Item
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Guo, H., T. Cynkowski, G. Cynkowska, P. A. Crooks, G. J. Jaffe, and P. Ashton. “"Smart" co-drugs. Rapid intravitreal delivery of 5-FU and prolonged delivery of steroid from the same erodible device.” In Investigative Ophthalmology and Visual Science, Vol. 38, 1997.
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Khawly, J. A., R. J. Lamben, and G. J. Jaffe. “Short and long term exposure of intraocular lenses to silicone oil after vitrectomy and silicone oil tamponade.” In Investigative Ophthalmology and Visual Science, Vol. 38, 1997.
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Chen, J., G. J. Jaffe, D. C. S. Yang, J. A. Khawly, and P. Ashton. “Development of a 1.5 year ganciclovir implant for CMV retinitis.” In Investigative Ophthalmology and Visual Science, Vol. 37, 1996.
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Chen, S. N., D. P. Hainsworth, T. A. Cox, and G. J. Jaffe. “Condensation on polymethylmethacrylate, acrylic polymer and silicone intraocular lenses after vitrectomy and fluid-air exchange.” In Investigative Ophthalmology and Visual Science, Vol. 37, 1996.
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Khawly, J. A., D. C. S. Yang, T. Cynkowski, A. Cynkowska, P. A. Crooks, P. Ashton, and G. J. Jaffe. “Pharmacologic inhibition of experimental proliferative vitreoretinopathy (PVR) using a triamcinolone/5-fluorouracil codrug sustained release pellet.” In Investigative Ophthalmology and Visual Science, Vol. 37, 1996.
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Yang, D. C. S., J. A. Khawly, D. P. Hainsworth, S. Chen, P. Ashton, H. Guo, and G. J. Jaffe. “Efficacy and pharmacokinetics of intravitreal sustained release triamcinolone/5-FU codrug suspension in the treatment of experimental PVR.” In Investigative Ophthalmology and Visual Science, Vol. 37, 1996.
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