Jamie Rae Privratsky
Associate Professor of Anesthesiology
Dr. Jamie Privratsky is an Assistant Professor in the Department of Anesthesiology at Duke University Medical Center. He is an anesthesiologist and intensive care physician scientist who practices critical care medicine at Duke University Hospital and Duke Regional Hospital. Dr. Privratsky’s research interests involve investigating strategies to treat postoperative and critical illness acute kidney injury (AKI) and prevent its transition to chronic kidney disease. In pre-clinical studies, he investigates mechanisms of injury and repair in mouse models of AKI. He also participates in epidemiologic studies in humans to better understand mechanisms of post-surgical and critical illness AKI. Dr. Privratsky is currently funded by a K08 award from NIGMS and an R01 award from NIDDK. He is also Assistant Director of the Duke Anesthesiology Academic Career Enrichment Scholars (ACES) residency research track.
Current Research Interests
Acute kidney injury (AKI) dramatically increases morbidity and mortality and is one of the most common forms of organ failure in perioperative and critically ill patients. Unresolved AKI leads to ongoing renal injury, fibrosis, and subsequent chronic kidney disease (CKD), which is a major risk factor for future cardiovascular events. Although AKI is not always preventable, interventions designed to promote renal healing and prevent CKD can improve long-term renal and cardiovascular health. My long-term goal is to develop targeted immunomodulatory and mitochondrial protective therapies for acute kidney injury (AKI) to prevent its transition to chronic kidney disease (CKD). Currently, we study mechanisms of injury and repair in mouse models of ischemic and septic AKI. We use a variety of genetically floxed mice in order to explore the mechanisms by which cytokines, immune cells, and metabolic pathways modulate kidney injury. We are also undertaking translational studies on humans to better understand mechanisms of post-surgical and critical illness AKI. For these studies we use patient medical and epidemiological data to better understand contributors to post-surgical AKI.
Current Appointments & Affiliations
- Associate Professor of Anesthesiology, Anesthesiology, Critical Care Medicine, Anesthesiology 2022
- Associate Professor in Pharmacology and Cancer Biology, Pharmacology & Cancer Biology, Basic Science Departments 2023
Contact Information
- 2301 Erwin Rd, DUMC Box 3094, Durham, NC 27710
- DUMC Box 3094, Durham, NC 27710
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jamie.privratsky@duke.edu
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LinkedIn for Jamie Privratsky
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Privratsky Lab website
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Twitter profile
- Background
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Education, Training, & Certifications
- Anesthesiology, Duke University 2016 - 2017
- Anesthesiology, Duke University 2013 - 2016
- M.D., Medical College of Wisconsin 2012
- Ph.D., Medical College of Wisconsin 2010
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Medical Licensure
- 2016-02185. North Carolina. 2016
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Previous Appointments & Affiliations
- Assistant Professor of Anesthesiology, Anesthesiology, Critical Care Medicine, Anesthesiology 2021 - 2022
- Assistant Professor of Anesthesiology, Anesthesiology, Critical Care Medicine, Anesthesiology 2017 - 2020
- Expertise
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Subject Headings
- Research
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Selected Grants
- Novel mitochondrial protective properties of annexin A1 awarded by National Institutes of Health 2021 - 2026
- The Role of the IL-1 Receptor in the AKI to CKD transition awarded by National Institutes of Health 2019 - 2024
- The role of macrophage IL-1 signaling in acute kidney injury and recovery awarded by International Anesthesia Research Society 2017 - 2019
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External Relationships
- McGraw-Hill Publishing
- Montefiore Medical Center
- Vanderbilt University
- Publications & Artistic Works
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Selected Publications
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Academic Articles
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Privratsky, Jamie R., Shintaro Ide, Yanting Chen, Hiroki Kitai, Jiafa Ren, Helene Fradin, Xiaohan Lu, Tomokazu Souma, and Steven D. Crowley. “A macrophage-endothelial immunoregulatory axis ameliorates septic acute kidney injury.” Kidney Int 103, no. 3 (March 2023): 514–28. https://doi.org/10.1016/j.kint.2022.10.008.Full Text Link to Item
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Privratsky, Jamie R., Matthew Fuller, Karthik Raghunathan, Tetsu Ohnuma, Raquel R. Bartz, Rebecca Schroeder, Thomas M. Price, et al. “Postoperative Acute Kidney Injury by Age and Sex: A Retrospective Cohort Association Study.” Anesthesiology 138, no. 2 (February 1, 2023): 184–94. https://doi.org/10.1097/ALN.0000000000004436.Full Text Link to Item
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Andrew, Benjamin Y., Carl F. Pieper, Anne D. Cherry, Jane F. Pendergast, Jamie R. Privratsky, Joseph P. Mathew, and Mark Stafford-Smith. “Identification of Trajectory-Based Acute Kidney Injury Phenotypes Among Cardiac Surgery Patients.” Ann Thorac Surg 114, no. 6 (December 2022): 2235–43. https://doi.org/10.1016/j.athoracsur.2021.11.047.Full Text Link to Item
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Leisman, Daniel E., Jamie R. Privratsky, Jake R. Lehman, Mabel N. Abraham, Omar Y. Yaipan, Mariana R. Brewer, Ana Nedeljkovic-Kurepa, et al. “Angiotensin II enhances bacterial clearance via myeloid signaling in a murine sepsis model.” Proc Natl Acad Sci U S A 119, no. 34 (August 23, 2022): e2211370119. https://doi.org/10.1073/pnas.2211370119.Full Text Link to Item
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Ren, Jiafa, Xiaohan Lu, Gentzon Hall, Jamie R. Privratsky, Matthew J. Robson, Randy D. Blakely, and Steven D. Crowley. “IL-1 receptor signaling in podocytes limits susceptibility to glomerular damage.” Am J Physiol Renal Physiol 322, no. 2 (February 1, 2022): F164–74. https://doi.org/10.1152/ajprenal.00353.2021.Full Text Link to Item
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Privratsky, Jamie R., Vijay Krishnamoorthy, Karthik Raghunathan, Tetsu Ohnuma, Mohammad R. Rasouli, Thorir E. Long, and Martin I. Sigurdsson. “Postoperative Acute Kidney Injury Is Associated With Progression of Chronic Kidney Disease Independent of Severity.” Anesth Analg 134, no. 1 (January 1, 2022): 49–58. https://doi.org/10.1213/ANE.0000000000005702.Full Text Link to Item
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Luu, David, Jordan Komisarow, Brianna M. Mills, Monica S. Vavilala, Daniel T. Laskowitz, Joseph Mathew, Michael L. James, et al. “Association of Severe Acute Kidney Injury with Mortality and Healthcare Utilization Following Isolated Traumatic Brain Injury.” Neurocrit Care 35, no. 2 (October 2021): 434–40. https://doi.org/10.1007/s12028-020-01183-z.Full Text Open Access Copy Link to Item
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Ren, Jiafa, Yuemei Xu, Xiaohan Lu, Liming Wang, Shintaro Ide, Gentzon Hall, Tomokazu Souma, Jamie R. Privratsky, Robert F. Spurney, and Steven D. Crowley. “Twist1 in podocytes ameliorates podocyte injury and proteinuria by limiting CCL2-dependent macrophage infiltration.” Jci Insight 6, no. 15 (August 9, 2021). https://doi.org/10.1172/jci.insight.148109.Full Text Link to Item
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Ren, Jiafa, Xiaohan Lu, Robert Griffiths, Jamie R. Privratsky, and Steven D. Crowley. “Twist1 in T Lymphocytes Augments Kidney Fibrosis after Ureteral Obstruction.” Kidney360 2, no. 5 (May 27, 2021): 784–94. https://doi.org/10.34067/KID.0007182020.Full Text Link to Item
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Suliman, Hagir, Qing Ma, Zhiquan Zhang, Jiafa Ren, Benjamin T. Morris, Steven D. Crowley, Luis Ulloa, and Jamie R. Privratsky. “Annexin A1 Tripeptide Mimetic Increases Sirtuin-3 and Augments Mitochondrial Function to Limit Ischemic Kidney Injury.” Front Physiol 12 (2021): 683098. https://doi.org/10.3389/fphys.2021.683098.Full Text Link to Item
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Privratsky, Jamie R., Yi-Ju Li, Carol Haynes, Mihai Podgoreanu, Joseph Mathew, Svati H. Shah, and Mark Stafford-Smith. “Apolipoprotein L1 (APOL1) Coding Variants Are Associated With Creatinine Rise After Cardiac Surgery.” J Cardiothorac Vasc Anesth 34, no. 12 (December 2020): 3314–20. https://doi.org/10.1053/j.jvca.2020.04.017.Full Text Link to Item
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Cherry, Anne D., Jennifer N. Hauck, Benjamin Y. Andrew, Yi-Ju Li, Jamie R. Privratsky, Lakshmi D. Kartha, Alina Nicoara, Annemarie Thompson, Joseph P. Mathew, and Mark Stafford-Smith. “Intraoperative renal resistive index threshold as an acute kidney injury biomarker.” J Clin Anesth 61 (May 2020): 109626. https://doi.org/10.1016/j.jclinane.2019.109626.Full Text Link to Item
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Ide, Shintaro, Yasuhito Yahara, Yoshihiko Kobayashi, Sarah A. Strausser, Kana Ide, Anisha Watwe, Shengjie Xu-Vanpala, et al. “Yolk-sac-derived macrophages progressively expand in the mouse kidney with age.” Elife 9 (April 17, 2020). https://doi.org/10.7554/eLife.51756.Full Text Link to Item
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Wen, Yi, Nathan P. Rudemiller, Jiandong Zhang, Xiaohan Lu, Jiafa Ren, Jamie R. Privratsky, Robert Griffiths, Junyi J. Zhang, Gianna E. Hammer, and Steven D. Crowley. “C-C Motif Chemokine Receptor 7 Exacerbates Hypertension Through Effects on T Lymphocyte Trafficking.” Hypertension 75, no. 3 (March 2020): 869–76. https://doi.org/10.1161/HYPERTENSIONAHA.119.14148.Full Text Link to Item
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Lu, Xiaohan, Nathan P. Rudemiller, Jamie R. Privratsky, Jiafa Ren, Yi Wen, Robert Griffiths, and Steven D. Crowley. “Classical Dendritic Cells Mediate Hypertension by Promoting Renal Oxidative Stress and Fluid Retention.” Hypertension 75, no. 1 (January 2020): 131–38. https://doi.org/10.1161/HYPERTENSIONAHA.119.13667.Full Text Link to Item
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Ren, Jiafa, Nathan P. Rudemiller, Yi Wen, Xiaohan Lu, Jamie R. Privratsky, and Steven D. Crowley. “The transcription factor Twist1 in the distal nephron but not in macrophages propagates aristolochic acid nephropathy.” Kidney Int 97, no. 1 (January 2020): 119–29. https://doi.org/10.1016/j.kint.2019.07.016.Full Text Link to Item
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Wen, Yi, Nathan P. Rudemiller, Jiandong Zhang, Taylor Robinette, Xiaohan Lu, Jiafa Ren, Jamie R. Privratsky, Sergei A. Nedospasov, and Steven D. Crowley. “TNF-α in T lymphocytes attenuates renal injury and fibrosis during nephrotoxic nephritis.” Am J Physiol Renal Physiol 318, no. 1 (January 1, 2020): F107–16. https://doi.org/10.1152/ajprenal.00347.2019.Full Text Link to Item
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Lu, Xiaohan, Nathan P. Rudemiller, Yi Wen, Jiafa Ren, Gianna E. Hammer, Robert Griffiths, Jamie R. Privratsky, Bo Yang, Matthew A. Sparks, and Steven D. Crowley. “A20 in Myeloid Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T-Cell Activation.” Circ Res 125, no. 12 (December 6, 2019): 1055–66. https://doi.org/10.1161/CIRCRESAHA.119.315343.Full Text Link to Item
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Lu, Xiaohan, Nathan P. Rudemiller, Jiafa Ren, Yi Wen, Bo Yang, Robert Griffiths, Jamie R. Privratsky, Babita Madan, David M. Virshup, and Steven D. Crowley. “Opposing actions of renal tubular- and myeloid-derived porcupine in obstruction-induced kidney fibrosis.” Kidney Int 96, no. 6 (December 2019): 1308–19. https://doi.org/10.1016/j.kint.2019.06.020.Full Text Link to Item
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Wen, Yi, Xiaohan Lu, Jiafa Ren, Jamie R. Privratsky, Bo Yang, Nathan P. Rudemiller, Jiandong Zhang, et al. “KLF4 in Macrophages Attenuates TNFα-Mediated Kidney Injury and Fibrosis.” J Am Soc Nephrol 30, no. 10 (October 2019): 1925–38. https://doi.org/10.1681/ASN.2019020111.Full Text Link to Item
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Ren, Jiafa, Jiandong Zhang, Nathan P. Rudemiller, Robert Griffiths, Yi Wen, Xiaohan Lu, Jamie R. Privratsky, Michael D. Gunn, and Steven D. Crowley. “Twist1 in Infiltrating Macrophages Attenuates Kidney Fibrosis via Matrix Metallopeptidase 13-Mediated Matrix Degradation.” J Am Soc Nephrol 30, no. 9 (September 2019): 1674–85. https://doi.org/10.1681/ASN.2018121253.Full Text Link to Item
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Yang, Bo, Lili Fu, Jamie R. Privratsky, Xiaohan Lu, Jiafa Ren, Changlin Mei, and Steven D. Crowley. “Interleukin-1 receptor activation aggravates autosomal dominant polycystic kidney disease by modulating regulated necrosis.” Am J Physiol Renal Physiol 317, no. 2 (August 1, 2019): F221–28. https://doi.org/10.1152/ajprenal.00104.2019.Full Text Link to Item
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Wen, Yi, Nathan P. Rudemiller, Jiandong Zhang, Alexander D. Jeffs, Robert Griffiths, Xiaohan Lu, Jiafa Ren, Jamie Privratsky, and Steven D. Crowley. “Stimulating Type 1 Angiotensin Receptors on T Lymphocytes Attenuates Renal Fibrosis.” Am J Pathol 189, no. 5 (May 2019): 981–88. https://doi.org/10.1016/j.ajpath.2019.02.004.Full Text Link to Item
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“Corrigendum.” American Journal of Physiology Renal Physiology 316, no. 5 (May 1, 2019): F1090–F1090. https://doi.org/10.1152/ajprenal.zh2-8545-corr.2019.Full Text
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Privratsky, Jamie R., Nian Wang, Yi Qi, Jiafa Ren, Benjamin T. Morris, John C. Hunting, G Allan Johnson, and Steven D. Crowley. “Dynamic contrast-enhanced MRI promotes early detection of toxin-induced acute kidney injury.” Am J Physiol Renal Physiol 316, no. 2 (February 1, 2019): F351–59. https://doi.org/10.1152/ajprenal.00416.2018.Full Text Link to Item
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Privratsky, Jamie R., Vanessa T. Schroder, Nazish Hashmi, and Yuriy S. Bronshteyn. “Initial Evaluation for Low-Pressure Cardiac Tamponade Using Focused Cardiac Ultrasound.” A a Pract 11, no. 12 (December 15, 2018): 356–58. https://doi.org/10.1213/XAA.0000000000000822.Full Text Link to Item
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Privratsky, Jamie R., Jiandong Zhang, Xiaohan Lu, Nathan Rudemiller, Qingqing Wei, Yen-Rei Yu, Michael D. Gunn, and Steven D. Crowley. “Interleukin 1 receptor (IL-1R1) activation exacerbates toxin-induced acute kidney injury.” Am J Physiol Renal Physiol 315, no. 3 (September 1, 2018): F682–91. https://doi.org/10.1152/ajprenal.00104.2018.Full Text Link to Item
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Privratsky, Jamie R., Sebastian Diaz, Alina Nicoara, and Mani A. Daneshmand. “In reply to: "Intra-aortic balloon pump protects against hydrostatic pulmonary oedema during peripheral venoarterial-extracorporeal membrane oxygenation".” Eur Heart J Acute Cardiovasc Care, May 1, 2018, 2048872618779772. https://doi.org/10.1177/2048872618779772.Full Text Link to Item
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Zhang, Jiandong, Nathan P. Rudemiller, Mehul B. Patel, QingQing Wei, Norah S. Karlovich, Alexander D. Jeffs, Min Wu, et al. “Competing Actions of Type 1 Angiotensin II Receptors Expressed on T Lymphocytes and Kidney Epithelium during Cisplatin-Induced AKI.” J Am Soc Nephrol 27, no. 8 (August 2016): 2257–64. https://doi.org/10.1681/ASN.2015060683.Full Text Open Access Copy Link to Item
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Privratsky, J. R., S. L. McCartney, T. K. Allen, and A. S. Habib. “Management of persistent cerebrospinal fluid leak using tissue adhesive.” Int J Obstet Anesth 24, no. 1 (February 2015): 87–88. https://doi.org/10.1016/j.ijoa.2014.07.007.Full Text Open Access Copy Link to Item
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Privratsky, Jamie R., and Peter J. Newman. “PECAM-1: regulator of endothelial junctional integrity.” Cell Tissue Res 355, no. 3 (March 2014): 607–19. https://doi.org/10.1007/s00441-013-1779-3.Full Text Link to Item
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Privratsky, Jamie R., Sarah B. Tilkens, Debra K. Newman, and Peter J. Newman. “PECAM-1 dampens cytokine levels during LPS-induced endotoxemia by regulating leukocyte trafficking.” Life Sci 90, no. 5–6 (January 30, 2012): 177–84. https://doi.org/10.1016/j.lfs.2011.11.002.Full Text Link to Item
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Privratsky, Jamie R., Nima Almassi, Michael L. Guralnick, Bradley J. Anderson, and R Corey O’Connor. “Outcomes of grafted bulbar urethroplasty in men with class II or III obesity.” Urology 78, no. 6 (December 2011): 1420–23. https://doi.org/10.1016/j.urology.2011.07.1429.Full Text Link to Item
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Privratsky, Jamie R., Cathy M. Paddock, Oliver Florey, Debra K. Newman, William A. Muller, and Peter J. Newman. “Relative contribution of PECAM-1 adhesion and signaling to the maintenance of vascular integrity.” J Cell Sci 124, no. Pt 9 (May 1, 2011): 1477–85. https://doi.org/10.1242/jcs.082271.Full Text Link to Item
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Privratsky, Jamie R., Debra K. Newman, and Peter J. Newman. “PECAM-1: conflicts of interest in inflammation.” Life Sci 87, no. 3–4 (July 17, 2010): 69–82. https://doi.org/10.1016/j.lfs.2010.06.001.Full Text Link to Item
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Privratsky, Jamie R., Benjamin E. Tourdot, Debra K. Newman, and Peter J. Newman. “The anti-inflammatory actions of platelet endothelial cell adhesion molecule-1 do not involve regulation of endothelial cell NF-kappa B.” J Immunol 184, no. 6 (March 15, 2010): 3157–63. https://doi.org/10.4049/jimmunol.0901944.Full Text Link to Item
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Ceylan-Isik, Asli F., Kelly K. Guo, Edward C. Carlson, Jamie R. Privratsky, Song-Jie Liao, Lu Cai, Alex F. Chen, and Jun Ren. “Metallothionein abrogates GTP cyclohydrolase I inhibition-induced cardiac contractile and morphological defects: role of mitochondrial biogenesis.” Hypertension 53, no. 6 (June 2009): 1023–31. https://doi.org/10.1161/HYPERTENSIONAHA.108.123422.Full Text Link to Item
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Ren, Jun, Jamie R. Privratsky, Xiaoping Yang, Feng Dong, and Edward C. Carlson. “Metallothionein alleviates glutathione depletion-induced oxidative cardiomyopathy in murine hearts.” Crit Care Med 36, no. 7 (July 2008): 2106–16. https://doi.org/10.1097/CCM.0b013e31817bf925.Full Text Link to Item
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Wold, Loren E., Asli F. Ceylan-Isik, Cindy X. Fang, Xiaoping Yang, Shi-Yan Li, Nair Sreejayan, Jamie R. Privratsky, and Jun Ren. “Metallothionein alleviates cardiac dysfunction in streptozotocin-induced diabetes: role of Ca2+ cycling proteins, NADPH oxidase, poly(ADP-Ribose) polymerase and myosin heavy chain isozyme.” Free Radic Biol Med 40, no. 8 (April 15, 2006): 1419–29. https://doi.org/10.1016/j.freeradbiomed.2005.12.009.Full Text Link to Item
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Li, Shi-Yan, Kish L. Golden, Yang Jiang, Guei-Jane Wang, Jamie R. Privratsky, Xiaochun Zhang, Anna R. Eason, Bruce Culver, and Jun Ren. “Inhibition of sarco(endo)plasmic reticulum Ca2+-ATPase differentially regulates contractile function in cardiac myocytes from normotensive and spontaneously hypertensive rats: role of Ca2+ regulatory proteins.” Cell Biochem Biophys 42, no. 1 (2005): 1–12. https://doi.org/10.1385/CBB:42:1:001.Full Text Link to Item
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Privratsky, Jamie R., Loren E. Wold, James R. Sowers, Mark T. Quinn, and Jun Ren. “AT1 blockade prevents glucose-induced cardiac dysfunction in ventricular myocytes: role of the AT1 receptor and NADPH oxidase.” Hypertension 42, no. 2 (August 2003): 206–12. https://doi.org/10.1161/01.HYP.0000082814.62655.85.Full Text Link to Item
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Aberle, Nicholas S., Jamie R. Privratsky, Larry Burd, and Jun Ren. “Combined acetaldehyde and nicotine exposure depresses cardiac contraction in ventricular myocytes: prevention by folic acid.” Neurotoxicol Teratol 25, no. 6 (2003): 731–36. https://doi.org/10.1016/j.ntt.2003.07.008.Full Text Link to Item
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Book Sections
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Cherry, A. D., B. Y. Andrew, J. R. Privratsky, and M. Stafford-Smith. “Renal Failure and Dialysis.” In Evidence-Based Practice in Perioperative Cardiac Anesthesia and Surgery, 597–618, 2020. https://doi.org/10.1007/978-3-030-47887-2_54.Full Text
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Conference Papers
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Johnson, Selby, Matthew Fuller, Riley League, Raquel R. Bartz, Ryan McDevitt, Krista L. Haines, Tetsu Ohnuma, et al. “Disparities in Survival after Severe COVID-19-related Critical Illness: A Nationwide Study in 466 ICUs in the US.” In Anesthesia and Analgesia, 134:230–34, 2022.Link to Item
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Martinez, Michael, Matthew Fuller, Karthik Raghunathan, Tetsu Ohnuma, Raquel R. Bartz, Rebecca Schroder, Thomas Price, et al. “Pre-menopausal age in females is associated with protection from development of post-operative acute kidney injury, but not mortality following AKI.” In Anesthesia and Analgesia, 134:256–57, 2022.Link to Item
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Huang, Hsin-I, Mark L. Jewell, Nourhan Youssef, Min-Nung Huang, Elizabeth R. Hauser, Brian E. Fee, Nathan P. Rudemiller, et al. “Th17 Immunity in the Colon Is Controlled by Two Novel Subsets of Colon-Specific Mononuclear Phagocytes.” In Front Immunol, 12:661290, 2021. https://doi.org/10.3389/fimmu.2021.661290.Full Text Link to Item
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Privratsky, Jamie, Vijay Krishnamoorthy, Karthik Raghunathan, Tetsu Ohnuma, Mohammed Rasouli, Thorir E. Long, and Martin I. Sigurdsson. “Postoperative Acute Kidney Injury is Associated with Progression of Chronic Kidney Disease Independent of Severity.” In Anesthesia and Analgesia, 132:209–11, 2021.Link to Item
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Privratsky, Jamie R., Jiafa Ren, Benjamin Morris, and Steven Crowley. “PROTECTIVE ROLE OF CX3CR1+MACROPHAGES IN MURINE SEPTIC AKI.” In Shock, 53:11–12, 2020.Link to Item
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Privratsky, Jamie R., Jiafa Ren, Benjamin T. Morris, and Steven D. Crowley. “INFLAMMATORY PROFILE OF MURINE SEPTIC AKI: ROLE OF CD11C+/CX3CR1+ANTIGEN PRESENTING CELLS.” In Shock, 51:56–56. LIPPINCOTT WILLIAMS & WILKINS, 2019.Link to Item
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Lu, Xiaohan, Nathan Rudemiller, Jamie Privratsky, Jiafa Ren, Yi Wen, Robert Griffiths, Michael D. Gunn, and Steven D. Crowley. “Classical Dendritic Cells Mediate Hypertension by Promoting Oxidative Stress and Renal Fluid Retention.” In Hypertension, Vol. 74, 2019.Link to Item
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Privratsky, Jamie, Jiafa Ren, Benjamin Morris, and Steven D. Crowley. “INFLAMMATORY PROFILE OF MURINE SEPTIC AKI: ROLE OF CD11C+/CX3CR1+ANTIGEN PRESENTING CELLS.” In Anesthesia and Analgesia, 128:206–206, 2019.Link to Item
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Lu, Xiaohan, Nathan Rudemiller, Jiandong Zhang, Jamie Privratsky, Gianna Hammer, Joyce Zhang, Yi Wen, Jiafa Ren, and Steven D. Crowley. “A20 in Dendritic Cells Protects Against Hypertension by Inhibiting Dendritic Cell-Mediated T Cell Activation.” In Hypertension, Vol. 72, 2018.Link to Item
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Privratsky, Jamie R., Benjamin E. Tourdot, Debra K. Newman, and Peter J. Newman. “The Anti-inflammatory Actions of PECAM-1 Do Not Involve Regulation of Endothelial Cell NF kappa B.” In Arteriosclerosis Thrombosis and Vascular Biology, 30:E257–E257. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Privratsky, Jamie R., Cathy M. Paddock, and Peter J. Newman. “Relative Contribution of PECAM-1 Adhesion and Signaling to the Maintenance of Vascular Integrity.” In Arteriosclerosis Thrombosis and Vascular Biology, 30:E304–E304. LIPPINCOTT WILLIAMS & WILKINS, 2010.Link to Item
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Privratsky, J. R., E. C. Carlson, and J. Ren. “Cardiac-specific overexpression of metallothionein prevents glutathione depletion-induced oxidative cardiomyopathy in isolated ventricular myocytes.” In Circulation, 106:201–2. LIPPINCOTT WILLIAMS & WILKINS, 2002.Link to Item
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Privratsky, Jamie R., Loren E. Wold, and Jun Ren. “06 AT1A receptor blockade by L-158,809 prevents the development of high [glucose]-induced diabetic cardiomyopathy: Role of NADPH oxidase.” In Journal of Molecular and Cellular Cardiology, 34:A12–A12. Elsevier BV, 2002. https://doi.org/10.1016/s0022-2828(02)90112-4.Full Text
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- Teaching & Mentoring
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Teaching Activities
- Critical Care Fellow Lecture series: block leader 2017-2018
- Scholarly, Clinical, & Service Activities
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Service to the Profession
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Clinical Activities
- I am an intensivist in the Duke Regional Hospital Critical Care Unit and the Duke University Hospital Surgical Intensive Care Unit. I also am an anesthesiologist in the General, Vascular, Transplant division of the Department of Anesthesiology.
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