Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellow in Cardiology, Medicine, Duke University School of Medicine 2005 - 2011
  • Resident, Medicine, Duke University School of Medicine 2002 - 2005
  • M.D., Harvard University 2002
• 

  Duke Appointment History

  • Assistant Professor of Medicine, Medicine, Cardiology, Medicine 2013 - 2018
  • Medical Instructor in the Department of Medicine, Medicine, Cardiology, Medicine 2011 - 2013
• Research
• 

  Selected Grants

  • APPRAISE ATP 2017 - 2022
  • Miracle-EF 2013 - 2014
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Gaeta, Stephen, Jacob N. Schroder, Mani A. Daneshmand, Kevin L. Thomas, Donald D. Hegland, Jonathan P. Piccini, James P. Daubert, Jason I. Koontz, and Albert Y. Sun. “Catheter Ablation of Mid-Myocardial Ventricular Tachycardia by Simultaneous Unipolar Radiofrequency Ablation With Half-Normal Saline Irrigation..” Jacc Clin Electrophysiol 4, no. 9 (September 2018): 1263–64. https://doi.org/10.1016/j.jacep.2018.05.004.
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    • Black-Maier, Eric, Xinru Ren, Benjamin A. Steinberg, Cynthia L. Green, Adam S. Barnett, Normita Sta Rosa, Sana M. Al-Khatib, et al. “Catheter ablation of atrial fibrillation in patients with heart failure and preserved ejection fraction..” Heart Rhythm 15, no. 5 (May 2018): 651–57. https://doi.org/10.1016/j.hrthm.2017.12.001.
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    • Il’Giovine, Zachary J., Adam D. DeVore, Chetan B. Patel, Jason Koontz, and Jacob Schroder. “Rethinking papillary muscle resection for refractory ventricular tachycardia in the LVAD era. A case report..” J Electrocardiol 50, no. 6 (November 2017): 964–65. https://doi.org/10.1016/j.jelectrocard.2017.07.007.
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    • Koontz, Jason, and James P. Daubert. “Do new tools help us identify substrate to target for ablation in ventricular tachycardia?.” J Cardiovasc Electrophysiol 28, no. 9 (September 2017): 1068–69. https://doi.org/10.1111/jce.13299.
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    • Dittrich, Howard C., Gregory K. Feld, Tristram D. Bahnson, A John Camm, Sergey Golitsyn, Amos Katz, Jason I. Koontz, Peter R. Kowey, Albert L. Waldo, and Arthur M. Brown. “COR-ART: A multicenter, randomized, double-blind, placebo-controlled dose-ranging study to evaluate single oral doses of vanoxerine for conversion of recent-onset atrial fibrillation or flutter to normal sinus rhythm..” Heart Rhythm 12, no. 6 (June 2015): 1105–12. https://doi.org/10.1016/j.hrthm.2015.02.014.
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    • Eyerly, Stephanie A., Tristram D. Bahnson, Jason I. Koontz, David P. Bradway, Douglas M. Dumont, Gregg E. Trahey, and Patrick D. Wolf. “Contrast in intracardiac acoustic radiation force impulse images of radiofrequency ablation lesions..” Ultrason Imaging 36, no. 2 (April 2014): 133–48. https://doi.org/10.1177/0161734613519602.
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    • Jackson, Kevin P., Donald D. Hegland, Camille Frazier-Mills, Jonathan P. Piccini, Jason I. Koontz, Brett D. Atwater, James P. Daubert, and Seth J. Worley. “Impact of using a telescoping-support catheter system for left ventricular lead placement on implant success and procedure time of cardiac resynchronization therapy..” Pacing Clin Electrophysiol 36, no. 5 (May 2013): 553–58. https://doi.org/10.1111/pace.12103.
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    • Shah, Svati H., Happy Thakkar, Asad A. Shah, Nicholas D. Andersen, James Bain, Carol Haynes, Michael Muehlbauer, et al. “Metabolites Reporting on Mitochondrial Function Predict Response to Biventricular Pacing.” Circulation 126, no. 21 (November 20, 2012).
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    • Eyerly, Stephanie A., Tristram D. Bahnson, Jason I. Koontz, David P. Bradway, Douglas M. Dumont, Gregg E. Trahey, and Patrick D. Wolf. “Intracardiac acoustic radiation force impulse imaging: a novel imaging method for intraprocedural evaluation of radiofrequency ablation lesions..” Heart Rhythm 9, no. 11 (November 2012): 1855–62. https://doi.org/10.1016/j.hrthm.2012.07.003.
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    • Williams, Eric S., Svati H. Shah, Jonathan P. Piccini, Albert Y. Sun, Jason I. Koontz, Sana M. Al-Khatib, and Patrick M. Hranitzky. “Predictors of mortality in patients with chronic kidney disease and an implantable defibrillator: an EPGEN substudy..” Europace 13, no. 12 (December 2011): 1717–22. https://doi.org/10.1093/europace/eur253.
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    • Piccini, Jonathan P., Jason I. Koontz, and Kevin P. Jackson. “Use of ventricular synchronized triggered atrial pacing to facilitate hemodynamic support during mapping and catheter ablation of ventricular vachycardia..” J Cardiovasc Electrophysiol 22, no. 10 (October 2011): 1174–78. https://doi.org/10.1111/j.1540-8167.2011.02034.x.
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    • Sun, Albert Y., Jason I. Koontz, Svati H. Shah, Jonathan P. Piccini, Kent R. Nilsson, Damian Craig, Carol Haynes, Simon G. Gregory, Patrick M. Hranitzky, and Geoffrey S. Pitt. “The S1103Y cardiac sodium channel variant is associated with implantable cardioverter-defibrillator events in blacks with heart failure and reduced ejection fraction..” Circ Cardiovasc Genet 4, no. 2 (April 2011): 163–68. https://doi.org/10.1161/CIRCGENETICS.110.958652.
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    • Koontz, Jason I., Daniel Haithcock, Valerie Cumbea, Anthony Waldron, Kristie Stricker, Amy Hughes, Kent Nilsson, et al. “Rationale and design of the Duke Electrophysiology Genetic and Genomic Studies (EPGEN) biorepository..” Am Heart J 158, no. 5 (November 2009): 719–25. https://doi.org/10.1016/j.ahj.2009.08.011.
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    • Koontz, Bridget F., Shiva Das, Kathy Temple, Sigrun Bynum, Suzanne Catalano, Jason I. Koontz, Gustavo S. Montana, and James R. Oleson. “Dosimetric and radiobiologic comparison of 3D conformal versus intensity modulated planning techniques for prostate bed radiotherapy..” Med Dosim 34, no. 3 (2009): 256–60. https://doi.org/10.1016/j.meddos.2008.10.005.
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    • Li, Hui, Xianyong Ma, Jinglan Wang, Jason Koontz, Marisa Nucci, and Jeffrey Sklar. “Effects of rearrangement and allelic exclusion of JJAZ1/SUZ12 on cell proliferation and survival..” Proc Natl Acad Sci U S A 104, no. 50 (December 11, 2007): 20001–6. https://doi.org/10.1073/pnas.0709986104.
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    • Nucci, Marisa R., David Harburger, Jason Koontz, Paola Dal Cin, and Jeffrey Sklar. “Molecular analysis of the JAZF1-JJAZ1 gene fusion by RT-PCR and fluorescence in situ hybridization in endometrial stromal neoplasms..” Am J Surg Pathol 31, no. 1 (January 2007): 65–70. https://doi.org/10.1097/01.pas.0000213327.86992.d1.
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    • Potti, Anil, Sayan Mukherjee, Rebecca Petersen, Holly K. Dressman, Andrea Bild, Jason Koontz, Robert Kratzke, et al. “A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer..” N Engl J Med 355, no. 6 (August 10, 2006): 570–80. https://doi.org/10.1056/NEJMoa060467.
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    • Koontz, J. I., A. L. Soreng, M. Nucci, F. C. Kuo, P. Pauwels, H. van Den Berghe, P. Dal Cin, J. A. Fletcher, and J. Sklar. “Frequent fusion of the JAZF1 and JJAZ1 genes in endometrial stromal tumors..” Proc Natl Acad Sci U S A 98, no. 11 (May 22, 2001): 6348–53. https://doi.org/10.1073/pnas.101132598.
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    • Morgan, J. A., Y. Yin, A. D. Borowsky, F. Kuo, N. Nourmand, J. I. Koontz, C. Reynolds, et al. “Breakpoints of the t(11;18)(q21;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma lie within or near the previously undescribed gene MALT1 in chromosome 18..” Cancer Res 59, no. 24 (December 15, 1999): 6205–13.
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    • Mashal, R. D., J. Koontz, and J. Sklar. “Detection of mutations by cleavage of DNA heteroduplexes with bacteriophage resolvases..” Nat Genet 9, no. 2 (February 1995): 177–83. https://doi.org/10.1038/ng0295-177.
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    • Gonzalez, J., J. I. Koontz, L. M. Hodges, K. R. Nilsson, M. Sabat, W. D. Harman, L. K. Neely, and W. H. Myers. “Osmium-Promoted Dipolar Cycloadditions with Pyrroles: An Efficient, Stereoselective Synthesis of 7-Azanorbornanes.” Journal of the American Chemical Society 117, no. 12 (January 1, 1995): 3405–21. https://doi.org/10.1021/ja00117a010.
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    • Hodges, L. M., J. Gonzalez, J. I. Koontz, W. H. Myers, and W. D. Harman. “β-Electrophilic Additions of Pentaammineosmium(II) β ² -Pyrrole Complexes.” Journal of Organic Chemistry 60, no. 7 (January 1, 1995): 2125–46. https://doi.org/10.1021/jo00112a037.
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    • Hodges, L. M., J. Gonzalez, J. I. Koontz, W. H. Myers, and W. D. Harman. “η²-Pyrrole Complexes as Synthons to Alkaloid Derivatives.” Journal of Organic Chemistry 58, no. 18 (January 1, 1993): 4788–90. https://doi.org/10.1021/jo00070a006.
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    • Myers, W. H., J. I. Koontz, and W. D. Harman. “Tautomerizations, Protonations, and Electrophilic Additions of η²-Coordinated Pyrroles.” Journal of the American Chemical Society 114, no. 14 (July 1, 1992): 5684–92. https://doi.org/10.1021/ja00040a030.
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  • Other Articles

    • Potti, Anil, Sayan Mukherjee, Rebecca Petersen, Holly K. Dressman, Andrea Bild, Jason Koontz, Robert Kratzke, et al. “Retraction: A genomic strategy to refine prognosis in early-stage non-small-cell lung cancer. N Engl J Med 2006;355:570-80..” N Engl J Med, March 24, 2011. https://doi.org/10.1056/NEJMc1101915.
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  • Conference Papers

    • Eyerly, S. A., T. D. Bahnson, J. I. Koontz, D. P. Bradway, D. M. Dumont, G. E. Trahey, and P. D. Wolf. “Confirmation of cardiac radiofrequency ablation treatment using intra-procedure acoustic radiation force impulse imaging.” In Ieee International Ultrasonics Symposium, Ius, 2037–40, 2012. https://doi.org/10.1109/ULTSYM.2012.0509.
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