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Jason Andrew Somarelli

Assistant Professor in Medicine
Medicine, Medical Oncology
Box 3053, Durham, NC 27710
3044 Gsrbi, LaSalle Street, Durham, NC 27710

Selected Grants


Inhibiting Rev1-mediated DNA translesion synthesis for cancer therapy

ResearchCo Investigator · Awarded by National Cancer Institute · 2024 - 2028

The Duke Preparing Research scholars In bioMEdical sciences (PRIME): Cancer Research Program

ResearchCo-Principal Investigator · Awarded by National Cancer Institute · 2023 - 2028

Duke Preparing Research Scholars in Biomedical Sciences- Post-Baccalaureate Research Education Program

Inst. Training Prgm or CMEMentor · Awarded by National Institute of General Medical Sciences · 2022 - 2027

Therapeutic Targeting of The Long Noncoding RNA SCHLAP1 in Aggressive Prostate Cancer

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2023 - 2025

Identifying novel CRM1 inhibitor combination therapies to treat sarcomas

ResearchPrincipal Investigator · Awarded by Karyopharm Therapeutics · 2021 - 2025

Defining the molecular physiologic impacts of stress on beaked whale hypoxia tolerance: implications for behavioral response

ResearchPrincipal Investigator · Awarded by Office of Naval Research · 2022 - 2025

Amgen Scholars Program at Duke

Inst. Training Prgm or CMEPrincipal Investigator · Awarded by Amgen Foundation, Inc. · 2023 - 2025

Targeting convergent oncogenic signaling during AR inhibition to overcome metastasis and immune evasion in prostate cancer

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2019 - 2025

An integrated physiology and genomics analysis to define molecular adaptations to diving

ResearchPrincipal Investigator · Awarded by Dolphin Quest · 2024 - 2025

Modeling tumor heterogeneity and therapy resistance in osteosarcoma using patient-derived organoids

ResearchCo Investigator · Awarded by Hyundai Hope on Wheels · 2021 - 2024

DIRECT - Diversifying Research and Experiential Learning in Cancer Training

Inst. Training Prgm or CMECo-Project Leader · Awarded by Emerson Collective · 2021 - 2024

Mitochondrial bioenergetics and colorectal cancer

ResearchPrincipal Investigator · Awarded by East Carolina University · 2024 - 2024

Evaluating the preclinical efficacy of multi-tyrosine kinase inhibitor TT-00420 in hormone therapy-resistant prostate cancer

ResearchPrincipal Investigator · Awarded by TransThera Biosciences Co. Ltd · 2024 - 2024

An integrated physiology and genomics analysis to define molecular adaptations to diving

ResearchPrincipal Investigator · Awarded by Dolphin Quest · 2022 - 2023

Investigating the role of LCP1 in metastatic progression of chondrosarcoma

ResearchSignificant Contributor · Awarded by The Musculoskeletal Tumor Society · 2022 - 2023

Systems Analysis of Epigenomic Architecture in Cancer Progression (Outreach Core)

ResearchCore Leader · Awarded by University of Texas Health Science Center at San Antonio · 2019 - 2023

The Duke University Marine Laboratory Scholars Program: Enhancing mentored research experiences for undergraduates

ResearchPrincipal Investigator · Awarded by Henry David Thoreau Foundation · 2021 - 2022

Targeting Convergent Mechanisms of Therapy Resistance, Metastasis, and Immune Evasion with CBP inhibitors

ResearchPrincipal Investigator · Awarded by FORMA Therapeutics, Inc. · 2020 - 2022

Targeting the p38/Snail/PD-L1 axis in hormone-therapy resistance and metastasis

ResearchPrincipal Investigator · Awarded by Department of Defense · 2018 - 2022

Bioengineering Plastic-Degrading Microbes To Eliminate Plastic Waste

ResearchPrincipal Investigator · Awarded by SeaWorld & Busch Gardens Conservation Fund · 2018 - 2020

Validation and interrogation of differentially expressed and alternatively spliced genes in African American prostate cancer

ResearchPostdoctoral Associate · Awarded by Department of Defense · 2014 - 2020

Marine Mammals Point the Way Toward New Therapies to Prevent Hypoxia

ResearchPrincipal Investigator · Awarded by Dolphin Quest · 2019 - 2020

Scholars in Marine Medicine: Mentored Research at the Nexus of the Marine Environment and Human Health.

ResearchPrincipal Investigator · Awarded by Dolphin Quest · 2019 - 2020

Testing the efficacy of AR degrading compounds in enzalutamide-resistant prostate cancer

ResearchPrincipal Investigator · Awarded by Arvinas Inc. · 2017 - 2019