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Elizabeth Jane Costello

Professor Emerita in Psychiatry and Behavioral Sciences
Psychiatry, Child & Family Mental Health & Community Psychiatry
Box 3454 Med Ctr, Durham, NC 27710
Brightleaf SQ Ste 22, 905 W Main St, Durham, NC 27701

Overview


Developmental epidemiology applies the research methods of findings of developmental science to epidemiology--the study of patterns of disease distribution in time and space. Developmental epidemiology can cover the life span, but my own work concentrates on childhood and adolescence. I study change and continuity in psychiatric disorders, in the context of change and
continuity in the risk factors for those disorders.

An important application of the work of the Developmental Epidemiology Program, of which I am Co-Director, is examining the need for, and use of, mental health services for children. This work sets the study of the mental health care system for children and adolescents within a conceptual framework which permits use of estimate unmet needs as well as identifying appropriate areas for preventive interventions. I am carrying out a longitudinal study based on 4,500 randomly selected children and adolescents living in the Appalachian mountains of western North Carolina. Findings from this study provide important information for federal and local policy makers, while at the same time testing ideas about the development of risk and resilience.

Current Appointments & Affiliations


Professor Emerita in Psychiatry and Behavioral Sciences · 2018 - Present Psychiatry, Child & Family Mental Health & Community Psychiatry, Psychiatry & Behavioral Sciences
Faculty Research Scholar of DuPRI's Population Research Center · 2010 - Present Duke Population Research Center, Duke Population Research Institute
Faculty Network Member of the Duke Institute for Brain Sciences · 2011 - Present Duke Institute for Brain Sciences, University Institutes and Centers
Affiliate of the Center for Child and Family Policy · 2015 - Present Center for Child and Family Policy, Sanford School of Public Policy

In the News


Published November 16, 2023
Which Duke Scholars Made the Most Cited List?
Published November 19, 2019
Global List of Highly Cited Puts Duke in Top Ten
Published November 4, 2016
Glad You Asked: Mental Illness Gets a Cold Shoulder

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Recent Publications


Long-term Outcomes of Childhood Family Income Supplements on Adult Functioning.

Journal Article JAMA Pediatr · October 1, 2022 IMPORTANCE: During an ongoing longitudinal cohort study, a casino opening created a natural cash transfer experiment. Some participating families received income supplements, and others did not. The children in this study are now adults. OBJECTIVE: To asse ... Full text Link to item Cite

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium.

Journal Article Mol Psychiatry · August 2020 To provide insights into the biology of opioid dependence (OD) and opioid use (i.e., exposure, OE), we completed a genome-wide analysis comparing 4503 OD cases, 4173 opioid-exposed controls, and 32,500 opioid-unexposed controls, including participants of E ... Full text Link to item Cite
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Recent Grants


Developmental methylomics of childhood trauma and its health consequences

ResearchCo Investigator · Awarded by Virginia Commonwealth University · 2014 - 2018

Diseases of Despair in Young Adulthood: Risk, Resilience, and Prevention

ResearchCo Investigator · Awarded by National Institutes of Health · 2018 - 2018

Early Substance Use in Rural American Indian and White/Anglo Youth

ResearchInvestigator · Awarded by National Institutes of Health · 2014 - 2018

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Education, Training & Certifications


University of London (United Kingdom) · 1981 Ph.D.