Elizabeth Jane Costello | Scholars@Duke

Elizabeth Jane Costello
Professor Emeritus in Psychiatry and Behavioral Sciences

Developmental epidemiology applies the research methods of findings of developmental science to epidemiology--the study of patterns of disease distribution in time and space. Developmental epidemiology can cover the life span, but my own work concentrates on childhood and adolescence. I study change and continuity in psychiatric disorders, in the context of change and
continuity in the risk factors for those disorders.

An important application of the work of the Developmental Epidemiology Program, of which I am Co-Director, is examining the need for, and use of, mental health services for children. This work sets the study of the mental health care system for children and adolescents within a conceptual
framework which permits use of estimate unmet needs as well as identifying appropriate areas for preventive interventions. I am carrying out a longitudinal study based on 4,500 randomly selected children and adolescents living in the Appalachian mountains of western North Carolina. Findings from this study provide important information for federal and local policy makers, while at the same time testing ideas about the development of risk and resilience.

Current Appointments & Affiliations

Professor Emeritus in Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Developmental Neuroscience, Psychiatry & Behavioral Sciences 2018
Faculty Research Scholar of DuPRI's Population Research Center, Duke Population Research Center, Duke Population Research Institute 2010
Faculty Network Member of the Duke Institute for Brain Sciences, Duke Institute for Brain Sciences, University Institutes and Centers 2011
Affiliate of the Center for Child and Family Policy, Center for Child and Family Policy, Sanford School of Public Policy 2015

Contact Information

Box 3454 Med Ctr, Durham, NC 27710
Brightleaf Sq Ste 22, 905 W Main St, Durham, NC 27701
jcostell@psych.mc.duke.edu (919) 385-0835

Background
Education, Training, & Certifications
- Ph.D., University of London (United Kingdom) 1981
Duke Appointment History
- Professor in the Department of Psychology and Neuroscience, Psychology and Neuroscience, Trinity College of Arts & Sciences 2008 - 2018
- Adjunct Professor in the Department of Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Developmental Neuroscience, Psychiatry & Behavioral Sciences 2018
- Professor of Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Developmental Neuroscience, Psychiatry & Behavioral Sciences 2000 - 2018
- Professor of Psychology-Social and Health Sciences, Psychology and Neuroscience, Trinity College of Arts & Sciences 2006 - 2009
- Associate Professor of Medical Psychology in the Department of Psychiatry and Behavioral Sciences, Psychiatry & Behavioral Sciences, Medical Psychology, Psychiatry & Behavioral Sciences 1995 - 2000
- Associate Professor of Medical Psychology in the Department of Psychiatry and Behavioral Sciences, Psychiatry, Child & Family Mental Health & Developmental Neuroscience, Psychiatry & Behavioral Sciences 1992 - 1995
- Assistant Professor of Medical Psychology, Psychiatry & Behavioral Sciences, Clinical Science Departments 1988 - 1992
Recognition
In the News
- NOV 19, 2019
  
  Global List of Highly Cited Puts Duke in Top Ten
- NOV 4, 2016
  
  Glad You Asked: Mental Illness Gets a Cold Shoulder
- JUN 24, 2016 Salon
  
  A Case for Universal Income
- JUN 22, 2016 Salon
  
  Many countries are weighing cash payments to citizens. Could it work in the U.S.?
- OCT 9, 2015 The Washington Post
  
  The remarkable thing that happens to poor kids when you give their parents a little money
- JUN 23, 2014 The New York Times
  
  Jane Costello comments: Seeing sons' violent potential, but finding little help or hope
- FEB 27, 2014
  
  Duke Faculty Testify in Congressional Hearings on Child Development, Presidential Authority
- FEB 27, 2014 The News & Observer
  
  Duke study shows effect of casino money on Cherokee families
- JAN 21, 2014 The New York Times
  
  Commentary: What happens when the poor receive a stipend?
- NOV 20, 2013 TIME
  
  Note to mentally ill teens: You’re on your own
- NOV 19, 2013 WUNC Radio News
  
  Duke study: Many teens in need of psychiatric help don't seek it
- NOV 18, 2013
  
  Most Teen Psychiatric Disorders Go Untreated
Research
Selected Grants
- Developmental methylomics of childhood trauma and its health consequences awarded by Virginia Commonwealth University 2014 - 2018
- Diseases of Despair in Young Adulthood: Risk, Resilience, and Prevention awarded by National Institutes of Health 2018
- Early Substance Use in Rural American Indian and White/Anglo Youth awarded by National Institutes of Health 2014 - 2018
- Vulnerability to Drug Abuse:Pathways to Recovery awarded by National Institutes of Health 1997 - 2017
- Early Substance Use in Rural American Indian and White/Anglo Youth awarded by University of North Carolina - Chapel Hill 2016 - 2017
- Pathways From Maltreatment to Substance Abuse awarded by National Institutes of Health 2010 - 2016
- Gene-Environment Interplay, Development, and Emotional Disorders awarded by National Institutes of Health 2008 - 2014
- A developmental model of gene-environment interplay in SUDs awarded by National Institutes of Health 2007 - 2014
- Prefrontal Function in Adolescent Limited vs Life Course Persistent SUD awarded by National Institutes of Health 2008 - 2014
- Sex, stress, emotional disorders: uniting preclinical and epidemiologic research awarded by National Institutes of Health 2008 - 2012
- Stress and Behavior in Health and Disease awarded by National Institutes of Health 1989 - 2011
- Training in Psychological Intervention Research awarded by National Institutes of Health 2006 - 2011
- Non-medical Use of ADHD Medication by College Students awarded by National Institutes of Health 2005 - 2009
- Multi-Site Longitudinal Analysis of Psychiatric Risk of SUDs awarded by National Institutes of Health 2003 - 2007
- Validity Without a Gold Standard awarded by National Institutes of Health 2002 - 2007
- Growing Up Violent in Rural America awarded by National Institutes of Health 2002 - 2007
- Prepubertal Comorbidity: Gender and Developmental Heterotypy awarded by National Institutes of Health 2001 - 2006
- Applying Developmental Epidemiology to Youth Services awarded by National Institutes of Health 1993 - 2004
- Caring For Children In The Community awarded by National Institutes of Health 1996 - 1999
- Caring For Children In The Community awarded by National Institutes of Health 1994 - 1999
- Caring For Children In The Community awarded by National Institutes of Health 1994 - 1999
- Applying Developmental Epidemiolgy To Youth Services awarded by National Institutes of Health 1993 - 1998
- Applying Developmental Epidemiology To Services For Youth awarded by National Institutes of Health 1993 - 1998
- Applying Developmental Epidemology To Youth Services awarded by National Institutes of Health 1993 - 1998
- Applying Developmental Epidemiology To Youth Services awarded by National Institutes of Health 1993 - 1998
- Service Use For Adm Comorbidity In Rual Adolescents awarded by National Institutes of Health 1991 - 1997
- Service Use For Adm Comorbidity In Rural Adolescents awarded by National Institutes of Health 1991 - 1996
- Data Set Analyses: Estimates Of Prevalence Of Sed In Child awarded by National Institutes of Health 1994 - 1995
- Hmo And Psychiatric Child Assessments: A Followup Study awarded by National Institutes of Health 1991 - 1993
- Hmo & Psychiatric Child Assessments: A Follow-Up Study awarded by National Institutes of Health 1990 - 1992
- Hmo And Child Psychiatric Assessment: A Follow-Up Study awarded by National Institutes of Health 1989 - 1992
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Choo, Candy Sc, Yong Chen, and Merrill McHoney. “Regarding: Optimal timing for inguinal hernia repair in premature infants: A systematic review and meta-analysis.” J Pediatr Surg 56, no. 5 (May 2021): 1083–84. https://doi.org/10.1016/j.jpedsurg.2020.12.030.
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  - Polimanti, Renato, Raymond K. Walters, Emma C. Johnson, Jeanette N. McClintick, Amy E. Adkins, Daniel E. Adkins, Silviu-Alin Bacanu, et al. “Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium.” Mol Psychiatry 25, no. 8 (August 2020): 1673–87. https://doi.org/10.1038/s41380-020-0677-9.
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  - Copeland, William E., Lauren Gaydosh, Sherika N. Hill, Jennifer Godwin, Kathleen Mullan Harris, E Jane Costello, and Lilly Shanahan. “Associations of Despair With Suicidality and Substance Misuse Among Young Adults.” Jama Netw Open 3, no. 6 (June 1, 2020): e208627. https://doi.org/10.1001/jamanetworkopen.2020.8627.
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  - Singh, Parvati, Ryan Brown, William E. Copeland, E Jane Costello, and Tim A. Bruckner. “Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment.” Biodemography Soc Biol 65, no. 2 (April 2020): 172–87. https://doi.org/10.1080/19485565.2020.1730155.
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  - Copeland, William E., Carol Worthman, Lilly Shanahan, E Jane Costello, and Adrian Angold. “Early Pubertal Timing and Testosterone Associated With Higher Levels of Adolescent Depression in Girls.” J Am Acad Child Adolesc Psychiatry 58, no. 12 (December 2019): 1197–1206. https://doi.org/10.1016/j.jaac.2019.02.007.
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  - Gifford, Elizabeth J., Lindsey Eldred Kozecke, Megan Golonka, Sherika N. Hill, E Jane Costello, Lilly Shanahan, and William E. Copeland. “Association of Parental Incarceration With Psychiatric and Functional Outcomes of Young Adults.” Jama Netw Open 2, no. 8 (August 2, 2019): e1910005. https://doi.org/10.1001/jamanetworkopen.2019.10005.
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  - Shanahan, Lilly, Sherika N. Hill, Lauren M. Gaydosh, Annekatrin Steinhoff, E Jane Costello, Kenneth A. Dodge, Kathleen Mullan Harris, and William E. Copeland. “Does Despair Really Kill? A Roadmap for an Evidence-Based Answer.” Am J Public Health 109, no. 6 (June 2019): 854–58. https://doi.org/10.2105/AJPH.2019.305016.
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  - Copeland, William E., Lilly Shanahan, Jennifer Hinesley, Robin F. Chan, Karolina A. Aberg, John A. Fairbank, Edwin J. C. G. van den Oord, and E Jane Costello. “Association of Childhood Trauma Exposure With Adult Psychiatric Disorders and Functional Outcomes.” Jama Netw Open 1, no. 7 (November 2, 2018): e184493. https://doi.org/10.1001/jamanetworkopen.2018.4493.
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  - Eg, Julie, Niels Bilenberg, Elizabeth J. Costello, and Rikke Wesselhoeft. “Self- and parent-reported depressive symptoms rated by the mood and feelings questionnaire.” Psychiatry Res 268 (October 2018): 419–25. https://doi.org/10.1016/j.psychres.2018.07.016.
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  - Akee, Randall, William Copeland, E Jane Costello, and Emilia Simeonova. “How Does Household Income Affect Child Personality Traits and Behaviors?” Am Econ Rev 108, no. 3 (March 2018): 775–827. https://doi.org/10.1257/aer.20160133.
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  - Copeland, William E., David B. Goldston, and E Jane Costello. “Adult Associations of Childhood Suicidal Thoughts and Behaviors: A Prospective, Longitudinal Analysis.” J Am Acad Child Adolesc Psychiatry 56, no. 11 (November 2017): 958-965.e4. https://doi.org/10.1016/j.jaac.2017.08.015.
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  - Hill, Sherika, Lilly Shanahan, E Jane Costello, and William Copeland. “Predicting Persistent, Limited, and Delayed Problematic Cannabis Use in Early Adulthood: Findings From a Longitudinal Study.” J Am Acad Child Adolesc Psychiatry 56, no. 11 (November 2017): 966-974.e4. https://doi.org/10.1016/j.jaac.2017.08.012.
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  - Clark, Shaunna L., Joseph L. McClay, Daniel E. Adkins, Gaurav Kumar, Karolina A. Aberg, Srilaxmi Nerella, Linying Xie, et al. “Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence.” Alcohol Clin Exp Res 41, no. 4 (April 2017): 711–18. https://doi.org/10.1111/acer.13352.
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  - Copeland, William E., Sherika Hill, E Jane Costello, and Lilly Shanahan. “Cannabis Use and Disorder From Childhood to Adulthood in a Longitudinal Community Sample With American Indians.” J Am Acad Child Adolesc Psychiatry 56, no. 2 (February 2017): 124-132.e2. https://doi.org/10.1016/j.jaac.2016.11.006.
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  - Costello, E Jane. “Early Detection and Prevention of Mental Health Problems: Developmental Epidemiology and Systems of Support.” J Clin Child Adolesc Psychol 45, no. 6 (November 2016): 710–17. https://doi.org/10.1080/15374416.2016.1236728.
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  - Costello, E Jane, William Copeland, and Adrian Angold. “The Great Smoky Mountains Study: developmental epidemiology in the southeastern United States.” Soc Psychiatry Psychiatr Epidemiol 51, no. 5 (May 2016): 639–46. https://doi.org/10.1007/s00127-015-1168-1.
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  - Copeland, William E., Cynthia M. Bulik, Nancy Zucker, Dieter Wolke, Suzet Tanya Lereya, and Elizabeth Jane Costello. “Does childhood bullying predict eating disorder symptoms? A prospective, longitudinal analysis.” Int J Eat Disord 48, no. 8 (December 2015): 1141–49. https://doi.org/10.1002/eat.22459.
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  - Copeland, William E., Dieter Wolke, Lilly Shanahan, and E Jane Costello. “Adult Functional Outcomes of Common Childhood Psychiatric Problems: A Prospective, Longitudinal Study.” Jama Psychiatry 72, no. 9 (September 2015): 892–99. https://doi.org/10.1001/jamapsychiatry.2015.0730.
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  - Adkins, Daniel E., Shaunna L. Clark, William E. Copeland, Martin Kennedy, Kevin Conway, Adrian Angold, Hermine Maes, et al. “Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood.” Twin Res Hum Genet 18, no. 4 (August 2015): 335–47. https://doi.org/10.1017/thg.2015.36.
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  - Copeland, William E., Melissa A. Brotman, and E Jane Costello. “Normative Irritability in Youth: Developmental Findings From the Great Smoky Mountains Study.” J Am Acad Child Adolesc Psychiatry 54, no. 8 (August 2015): 635–42. https://doi.org/10.1016/j.jaac.2015.05.008.
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  - Lereya, Suzet Tanya, William E. Copeland, E Jane Costello, and Dieter Wolke. “Adult mental health consequences of peer bullying and maltreatment in childhood: two cohorts in two countries.” Lancet Psychiatry 2, no. 6 (June 2015): 524–31. https://doi.org/10.1016/S2215-0366(15)00165-0.
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  - Shanahan, L., N. Zucker, W. E. Copeland, C. L. Bondy, H. L. Egger, and E. J. Costello. “Childhood somatic complaints predict generalized anxiety and depressive disorders during young adulthood in a community sample.” Psychol Med 45, no. 8 (June 2015): 1721–30. https://doi.org/10.1017/S0033291714002840.
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  - Erskine, H. E., T. E. Moffitt, W. E. Copeland, E. J. Costello, A. J. Ferrari, G. Patton, L. Degenhardt, T. Vos, H. A. Whiteford, and J. G. Scott. “A heavy burden on young minds: the global burden of mental and substance use disorders in children and youth.” Psychol Med 45, no. 7 (May 2015): 1551–63. https://doi.org/10.1017/S0033291714002888.
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  - Copeland, William E., Lilly Shanahan, Maryann Davis, Barbara J. Burns, Adrian Angold, and E Jane Costello. “Increase in untreated cases of psychiatric disorders during the transition to adulthood.” Psychiatr Serv 66, no. 4 (April 1, 2015): 397–403. https://doi.org/10.1176/appi.ps.201300541.
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  - Costello, E Jane, and Barbara Maughan. “Annual research review: Optimal outcomes of child and adolescent mental illness.” J Child Psychol Psychiatry 56, no. 3 (March 2015): 324–41. https://doi.org/10.1111/jcpp.12371.
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  - Costello, E Jane. “Commentary: 'Diseases of the world': from epidemiology to etiology of child and adolescent psychopathology--a commentary on Polanczyk et al. (2015).” J Child Psychol Psychiatry 56, no. 3 (March 2015): 366–69. https://doi.org/10.1111/jcpp.12402.
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  - Shanahan, Lilly, Nancy Zucker, William E. Copeland, E Jane Costello, and Adrian Angold. “Are children and adolescents with food allergies at increased risk for psychopathology?” J Psychosom Res 77, no. 6 (December 2014): 468–73. https://doi.org/10.1016/j.jpsychores.2014.10.005.
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  - Costello, E Jane. “Adult outcomes of childhood bullying victimization.” Am J Psychiatry 171, no. 7 (July 2014): 709–11. https://doi.org/10.1176/appi.ajp.2014.14040466.
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  - Copeland, William E., Lilly Shanahan, Helen Egger, Adrian Angold, and E Jane Costello. “Adult diagnostic and functional outcomes of DSM-5 disruptive mood dysregulation disorder.” Am J Psychiatry 171, no. 6 (June 2014): 668–74. https://doi.org/10.1176/appi.ajp.2014.13091213.
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  - Copeland, William E., Dieter Wolke, Suzet Tanya Lereya, Lilly Shanahan, Carol Worthman, and E Jane Costello. “Childhood bullying involvement predicts low-grade systemic inflammation into adulthood.” Proc Natl Acad Sci U S A 111, no. 21 (May 27, 2014): 7570–75. https://doi.org/10.1073/pnas.1323641111.
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  - Shanahan, Lilly, William E. Copeland, Adrian Angold, Carmen L. Bondy, and E Jane Costello. “Sleep problems predict and are predicted by generalized anxiety/depression and oppositional defiant disorder.” J Am Acad Child Adolesc Psychiatry 53, no. 5 (May 2014): 550–58. https://doi.org/10.1016/j.jaac.2013.12.029.
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  - Costello, E Jane, Jian-ping He, Nancy A. Sampson, Ronald C. Kessler, and Kathleen Ries Merikangas. “Services for adolescents with psychiatric disorders: 12-month data from the National Comorbidity Survey-Adolescent.” Psychiatr Serv 65, no. 3 (March 1, 2014): 359–66. https://doi.org/10.1176/appi.ps.201100518.
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  - Copeland, William E., Adrian Angold, Lilly Shanahan, and E Jane Costello. “Longitudinal patterns of anxiety from childhood to adulthood: the Great Smoky Mountains Study.” J Am Acad Child Adolesc Psychiatry 53, no. 1 (January 2014): 21–33. https://doi.org/10.1016/j.jaac.2013.09.017.
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  - Sung, Minje, Al Erkanli, and E Jane Costello. “Estimating the causal effect of conduct disorder on the time from first substance use to substance use disorders using g-estimation.” Subst Abus 35, no. 2 (2014): 141–46. https://doi.org/10.1080/08897077.2013.816651.
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  - Costello, E Jane, William E. Copeland, Lilly Shanahan, Carol M. Worthman, and Adrian Angold. “C-reactive protein and substance use disorders in adolescence and early adulthood: a prospective analysis.” Drug Alcohol Depend 133, no. 2 (December 1, 2013): 712–17. https://doi.org/10.1016/j.drugalcdep.2013.08.027.
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  - Franz, Lauren, Adrian Angold, William Copeland, E Jane Costello, Nissa Towe-Goodman, and Helen Egger. “Preschool anxiety disorders in pediatric primary care: prevalence and comorbidity.” J Am Acad Child Adolesc Psychiatry 52, no. 12 (December 2013): 1294-1303.e1. https://doi.org/10.1016/j.jaac.2013.09.008.
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  - Shanahan, Lilly, William E. Copeland, Carol M. Worthman, Adrian Angold, and E Jane Costello. “Children with both asthma and depression are at risk for heightened inflammation.” J Pediatr 163, no. 5 (November 2013): 1443–47. https://doi.org/10.1016/j.jpeds.2013.06.046.
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  - Shanahan, Lilly, William E. Copeland, Carol M. Worthman, Alaattin Erkanli, Adrian Angold, and E Jane Costello. “Sex-differentiated changes in C-reactive protein from ages 9 to 21: the contributions of BMI and physical/sexual maturation.” Psychoneuroendocrinology 38, no. 10 (October 2013): 2209–17. https://doi.org/10.1016/j.psyneuen.2013.04.010.
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  - Wolke, Dieter, William E. Copeland, Adrian Angold, and E Jane Costello. “Impact of bullying in childhood on adult health, wealth, crime, and social outcomes.” Psychol Sci 24, no. 10 (October 2013): 1958–70. https://doi.org/10.1177/0956797613481608.
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  - Stringaris, Argyris, Barbara Maughan, William S. Copeland, E Jane Costello, and Adrian Angold. “Irritable mood as a symptom of depression in youth: prevalence, developmental, and clinical correlates in the Great Smoky Mountains Study.” J Am Acad Child Adolesc Psychiatry 52, no. 8 (August 2013): 831–40. https://doi.org/10.1016/j.jaac.2013.05.017.
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  - Copeland, William E., Carol E. Adair, Paul Smetanin, David Stiff, Carla Briante, Ian Colman, David Fergusson, et al. “Diagnostic transitions from childhood to adolescence to early adulthood.” J Child Psychol Psychiatry 54, no. 7 (July 2013): 791–99. https://doi.org/10.1111/jcpp.12062.
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  - Aberg, Karolina A., Lin Y. Xie, Srilaxmi Nerella, William E. Copeland, E Jane Costello, and Edwin J. C. G. van den Oord. “High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot.” Epigenetics 8, no. 5 (May 2013): 542–47. https://doi.org/10.4161/epi.24508.
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  - Green, Jennifer Greif, Katie A. McLaughlin, Margarita Alegría, E Jane Costello, Michael J. Gruber, Kimberly Hoagwood, Philip J. Leaf, Serene Olin, Nancy A. Sampson, and Ronald C. Kessler. “School mental health resources and adolescent mental health service use.” J Am Acad Child Adolesc Psychiatry 52, no. 5 (May 2013): 501–10. https://doi.org/10.1016/j.jaac.2013.03.002.
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  - Akee, Randall, Emilia Simeonova, William Copeland, Adrian Angold, and E Jane Costello. “Young Adult Obesity and Household Income: Effects of Unconditional Cash Transfers.” Am Econ J Appl Econ 5, no. 2 (April 1, 2013): 1–28. https://doi.org/10.1257/app.5.2.1.
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  - Copeland, William E., Dieter Wolke, Adrian Angold, and E Jane Costello. “Adult psychiatric outcomes of bullying and being bullied by peers in childhood and adolescence.” Jama Psychiatry 70, no. 4 (April 2013): 419–26. https://doi.org/10.1001/jamapsychiatry.2013.504.
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  - Costello, E Jane, Lindon Eaves, Patrick Sullivan, Martin Kennedy, Kevin Conway, Daniel E. Adkins, A. Angold, et al. “Genes, environments, and developmental research: methods for a multi-site study of early substance abuse.” Twin Res Hum Genet 16, no. 2 (April 2013): 505–15. https://doi.org/10.1017/thg.2013.6.
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  - Copeland, William E., Adrian Angold, E Jane Costello, and Helen Egger. “Prevalence, comorbidity, and correlates of DSM-5 proposed disruptive mood dysregulation disorder.” Am J Psychiatry 170, no. 2 (February 2013): 173–79. https://doi.org/10.1176/appi.ajp.2012.12010132.
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  - Copeland, William E., Lilly Shanahan, Alaattin Erkanli, E Jane Costello, and Adrian Angold. “Indirect comorbidity in childhood and adolescence.” Front Psychiatry 4 (2013): 144. https://doi.org/10.3389/fpsyt.2013.00144.
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  - Copeland, W. E., L. Shanahan, C. Worthman, A. Angold, and E. J. Costello. “Generalized anxiety and C-reactive protein levels: a prospective, longitudinal analysis.” Psychol Med 42, no. 12 (December 2012): 2641–50. https://doi.org/10.1017/S0033291712000554.
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  - McLaughlin, Katie A., Jennifer Greif Green, Margarita Alegría, E. Jane Costello, Michael J. Gruber, Nancy A. Sampson, and Ronald C. Kessler. “Food insecurity and mental disorders in a national sample of U.S. adolescents.” J Am Acad Child Adolesc Psychiatry 51, no. 12 (December 2012): 1293–1303. https://doi.org/10.1016/j.jaac.2012.09.009.
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  - Copeland, W. E., A. Angold, L. Shanahan, J. Dreyfuss, I. Dlamini, and E. J. Costello. “Predicting persistent alcohol problems: a prospective analysis from the Great Smoky Mountain Study.” Psychol Med 42, no. 9 (September 2012): 1925–35. https://doi.org/10.1017/S0033291711002790.
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  - McLaughlin, Katie A., E Jane Costello, William Leblanc, Nancy A. Sampson, and Ronald C. Kessler. “Socioeconomic status and adolescent mental disorders.” Am J Public Health 102, no. 9 (September 2012): 1742–50. https://doi.org/10.2105/AJPH.2011.300477.
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  - Angold, Adrian, Alaattin Erkanli, William Copeland, Robert Goodman, Prudence W. Fisher, and E Jane Costello. “Psychiatric diagnostic interviews for children and adolescents: a comparative study.” J Am Acad Child Adolesc Psychiatry 51, no. 5 (May 2012): 506–17. https://doi.org/10.1016/j.jaac.2012.02.020.
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  - Kessler, Ronald C., Shelli Avenevoli, E Jane Costello, Katholiki Georgiades, Jennifer Greif Green, Michael J. Gruber, Jian-ping He, et al. “Prevalence, persistence, and sociodemographic correlates of DSM-IV disorders in the National Comorbidity Survey Replication Adolescent Supplement.” Arch Gen Psychiatry 69, no. 4 (April 2012): 372–80. https://doi.org/10.1001/archgenpsychiatry.2011.160.
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  - Kessler, Ronald C., Shelli Avenevoli, Jane Costello, Jennifer Greif Green, Michael J. Gruber, Katie A. McLaughlin, Maria Petukhova, Nancy A. Sampson, Alan M. Zaslavsky, and Kathleen Ries Merikangas. “Severity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication Adolescent Supplement.” Arch Gen Psychiatry 69, no. 4 (April 2012): 381–89. https://doi.org/10.1001/archgenpsychiatry.2011.1603.
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  - Copeland, William E., Lilly Shanahan, Carol Worthman, Adrian Angold, and E Jane Costello. “Cumulative depression episodes predict later C-reactive protein levels: a prospective analysis.” Biol Psychiatry 71, no. 1 (January 1, 2012): 15–21. https://doi.org/10.1016/j.biopsych.2011.09.023.
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  - Jensen, Peter S., Eliot Goldman, David Offord, Elizabeth J. Costello, Robert Friedman, Barbara Huff, Maura Crowe, et al. “Overlooked and underserved: "action signs" for identifying children with unmet mental health needs.” Pediatrics 128, no. 5 (November 2011): 970–79. https://doi.org/10.1542/peds.2009-0367.
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  - Shanahan, L., W. E. Copeland, E. J. Costello, and A. Angold. “Child-, adolescent- and young adult-onset depressions: differential risk factors in development?” Psychol Med 41, no. 11 (November 2011): 2265–74. https://doi.org/10.1017/S0033291711000675.
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  - Costello, E Jane, William Copeland, and Adrian Angold. “Trends in psychopathology across the adolescent years: what changes when children become adolescents, and when adolescents become adults?” J Child Psychol Psychiatry 52, no. 10 (October 2011): 1015–25. https://doi.org/10.1111/j.1469-7610.2011.02446.x.
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  - Collins, Pamela Y., Vikram Patel, Sarah S. Joestl, Dana March, Thomas R. Insel, Abdallah S. Daar, Abdallah S. Scientific Advisory Board and the Executive Committee of the Grand Challenges on Global Mental Health, et al. “Grand challenges in global mental health.” Nature 475, no. 7354 (July 6, 2011): 27–30. https://doi.org/10.1038/475027a.
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  - Copeland, William E., Hui Sun, E Jane Costello, Adrian Angold, Markus A. Heilig, and Christina S. Barr. “Child μ-opioid receptor gene variant influences parent-child relations.” Neuropsychopharmacology 36, no. 6 (May 2011): 1165–70. https://doi.org/10.1038/npp.2010.251.
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  - Copeland, William, Lilly Shanahan, E Jane Costello, and Adrian Angold. “Cumulative prevalence of psychiatric disorders by young adulthood: a prospective cohort analysis from the Great Smoky Mountains Study.” J Am Acad Child Adolesc Psychiatry 50, no. 3 (March 2011): 252–61. https://doi.org/10.1016/j.jaac.2010.12.014.
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  - Kaplow, Julie B., Jessica Saunders, Adrian Angold, and E Jane Costello. “Psychiatric symptoms in bereaved versus nonbereaved youth and young adults: a longitudinal epidemiological study.” J Am Acad Child Adolesc Psychiatry 49, no. 11 (November 2010): 1145–54. https://doi.org/10.1016/j.jaac.2010.08.004.
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  - Rowe, Richard, E Jane Costello, Adrian Angold, William E. Copeland, and Barbara Maughan. “Developmental pathways in oppositional defiant disorder and conduct disorder.” J Abnorm Psychol 119, no. 4 (November 2010): 726–38. https://doi.org/10.1037/a0020798.
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  - Copeland, William, Lilly Shanahan, Shari Miller, E Jane Costello, Adrian Angold, and Barbara Maughan. “Outcomes of early pubertal timing in young women: a prospective population-based study.” Am J Psychiatry 167, no. 10 (October 2010): 1218–25. https://doi.org/10.1176/appi.ajp.2010.09081190.
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  - Copeland, William E., Gordon Keeler, Adrian Angold, and E Jane Costello. “Posttraumatic stress without trauma in children.” Am J Psychiatry 167, no. 9 (September 2010): 1059–65. https://doi.org/10.1176/appi.ajp.2010.09020178.
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  - Costello, E. J. “In reply.” Jama Journal of the American Medical Association 304, no. 9 (September 1, 2010): 963. https://doi.org/10.1001/jama.2010.1241.
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  - Sterba, Sonya K., William Copeland, Helen L. Egger, E. Jane Costello, Alaattin Erkanli, and Adrian Angold. “Longitudinal dimensionality of adolescent psychopathology: testing the differentiation hypothesis.” J Child Psychol Psychiatry 51, no. 8 (August 2010): 871–84. https://doi.org/10.1111/j.1469-7610.2010.02234.x.
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  - Costello, E Jane, Alaattin Erkanli, William Copeland, and Adrian Angold. “Association of family income supplements in adolescence with development of psychiatric and substance use disorders in adulthood among an American Indian population.” Jama 303, no. 19 (May 19, 2010): 1954–60. https://doi.org/10.1001/jama.2010.621.
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  - Rabiner, David L., Arthur D. Anastopoulos, E Jane Costello, Rick H. Hoyle, and H Scott Swartzwelder. “Predictors of nonmedical ADHD medication use by college students.” J Atten Disord 13, no. 6 (May 2010): 640–48. https://doi.org/10.1177/1087054709334505.
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  - Costello, E Jane, and Adrian Angold. “Developmental transitions to psychopathology: are there prodromes of substance use disorders?” J Child Psychol Psychiatry 51, no. 4 (April 2010): 526–32. https://doi.org/10.1111/j.1469-7610.2010.02221.x.
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  - Akee, Randall K. Q., William E. Copeland, Gordon Keeler, Adrian Angold, and Elizabeth J. Costello. “Parents' Incomes and Children's Outcomes: A Quasi-Experiment.” Am Econ J Appl Econ 2, no. 1 (January 2010): 86–115. https://doi.org/10.1257/app.2.1.86.
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  - Costello, E Jane. “Grand challenges in child and neurodevelopmental psychiatry.” Front Psychiatry 1 (2010): 14. https://doi.org/10.3389/fpsyt.2010.00014.
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  - Foster, H., D. S. Nagin, J. Hagan, A. Angold, and E. J. Costello. “Specifying criminogenic strains: Stress dynamics and conduct disorder trajectories.” Deviant Behavior 31, no. 5 (January 1, 2010): 440–75. https://doi.org/10.1080/01639620903231340.
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  - Blase, Stacey L., Adrianne N. Gilbert, Arthur D. Anastopoulos, E Jane Costello, Rick H. Hoyle, H Scott Swartzwelder, and David L. Rabiner. “Self-reported ADHD and adjustment in college: cross-sectional and longitudinal findings.” J Atten Disord 13, no. 3 (November 2009): 297–309. https://doi.org/10.1177/1087054709334446.
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  - Rabiner, David L., Arthur D. Anastopoulos, E Jane Costello, Rick H. Hoyle, Sean Esteban McCabe, and H Scott Swartzwelder. “Motives and perceived consequences of nonmedical ADHD medication use by college students: are students treating themselves for attention problems?” J Atten Disord 13, no. 3 (November 2009): 259–70. https://doi.org/10.1177/1087054708320399.
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  - Brown, Ryan, William E. Copeland, E Jane Costello, Alaattin Erkanli, and Carol M. Worthman. “Family and Community Influences on Educational Outcomes Among Appalachian Youth.” J Community Psychol 37, no. 7 (September 2009): 795–808. https://doi.org/10.1002/jcop.20331.
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  - Costello, J., and A. Angold. “Measurement and design for life course studies of individual differences and development,” September 1, 2009. https://doi.org/10.1093/acprof:oso/9780198528487.003.0002.
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  - Rabiner, David L., Arthur D. Anastopoulos, E Jane Costello, Rick H. Hoyle, Sean Esteban McCabe, and H Scott Swartzwelder. “The misuse and diversion of prescribed ADHD medications by college students.” J Atten Disord 13, no. 2 (September 2009): 144–53. https://doi.org/10.1177/1087054708320414.
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  - Copeland, William E., Lilly Shanahan, E Jane Costello, and Adrian Angold. “Childhood and adolescent psychiatric disorders as predictors of young adult disorders.” Arch Gen Psychiatry 66, no. 7 (July 2009): 764–72. https://doi.org/10.1001/archgenpsychiatry.2009.85.
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  - Brown, Ryan A., David H. Rehkopf, William E. Copeland, E Jane Costello, and Carol M. Worthman. “Lifecourse Priorities Among Appalachian Emerging Adults: Revisiting Wallace's Organization of Diversity.” Ethos 37, no. 2 (June 2009). https://doi.org/10.1111/j.1548-1352.2009.01040.x.
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  - Kessler, Ronald C., Shelli Avenevoli, E Jane Costello, Jennifer Greif Green, Michael J. Gruber, Steven Heeringa, Kathleen R. Merikangas, Beth-Ellen Pennell, Nancy A. Sampson, and Alan M. Zaslavsky. “Design and field procedures in the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A).” Int J Methods Psychiatr Res 18, no. 2 (June 2009): 69–83. https://doi.org/10.1002/mpr.279.
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  - Brown, Ryan A., Jennifer Kuzara, William E. Copeland, E Jane Costello, Adrian Angold, and Carol M. Worthman. “Moving from ethnography to epidemiology: lessons learned in Appalachia.” Ann Hum Biol 36, no. 3 (May 2009): 248–60. https://doi.org/10.1080/03014460902832942.
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  - Worthman, Carol M., and E Jane Costello. “Tracking biocultural pathways in population health: the value of biomarkers.” Ann Hum Biol 36, no. 3 (May 2009): 281–97. https://doi.org/10.1080/03014460902832934.
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  - Copeland, William, Lilly Shanahan, E Jane Costello, and Adrian Angold. “Configurations of common childhood psychosocial risk factors.” J Child Psychol Psychiatry 50, no. 4 (April 2009): 451–59. https://doi.org/10.1111/j.1469-7610.2008.02005.x.
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  - Costello, Jane. “Editorial: How epidemiology helps.” J Child Psychol Psychiatry 50, no. 4 (April 2009): 361–62. https://doi.org/10.1111/j.1469-7610.2009.02102.x.
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  - Kessler, Ronald C., Shelli Avenevoli, E Jane Costello, Jennifer Greif Green, Michael J. Gruber, Steven Heeringa, Kathleen R. Merikangas, Beth-Ellen Pennell, Nancy A. Sampson, and Alan M. Zaslavsky. “National comorbidity survey replication adolescent supplement (NCS-A): II. Overview and design.” J Am Acad Child Adolesc Psychiatry 48, no. 4 (April 2009): 380–85. https://doi.org/10.1097/CHI.0b013e3181999705.
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  - Merikangas, Kathleen R., Shelli Avenevoli, E Jane Costello, Doreen Koretz, and Ronald C. Kessler. “National comorbidity survey replication adolescent supplement (NCS-A): I. Background and measures.” J Am Acad Child Adolesc Psychiatry 48, no. 4 (April 2009): 367–79. https://doi.org/10.1097/CHI.0b013e31819996f1.
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  - Beskow, L. M., L. Dame, and E. J. Costello. “Response.” Science 323, no. 5919 (March 18, 2009): 1289–90. https://doi.org/10.1126/science.323.5919.1289.
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  - Costello, E. J. “Using Epidemiological and Longitudinal Approaches to Study Causal Hypotheses,” February 10, 2009, 58–70. https://doi.org/10.1002/9781444300895.ch5.
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  - Angold, Adrian, and E Jane Costello. “Nosology and measurement in child and adolescent psychiatry.” J Child Psychol Psychiatry 50, no. 1–2 (January 2009): 9–15. https://doi.org/10.1111/j.1469-7610.2008.01981.x.
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  - Beskow, Laura M., Lauren Dame, and E Jane Costello. “Research ethics. Certificates of confidentiality and compelled disclosure of data.” Science 322, no. 5904 (November 14, 2008): 1054–55. https://doi.org/10.1126/science.1164100.
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  - Brown, Ryan A., Nancy E. Adler, Carol M. Worthman, William E. Copeland, E Jane Costello, and Adrian Angold. “Cultural and community determinants of subjective social status among Cherokee and White youth.” Ethn Health 13, no. 4 (September 2008): 289–303. https://doi.org/10.1080/13557850701837302.
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  - Costello, J. “Editorial: Letter from America.” Journal of Child Psychology and Psychiatry and Allied Disciplines 49, no. 7 (July 1, 2008): 689–90. https://doi.org/10.1111/j.1469-7610.2008.01947.x.
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  - Rabiner, David L., Arthur D. Anastopoulos, Jane Costello, Rick H. Hoyle, and H Scott Swartzwelder. “Adjustment to college in students with ADHD.” J Atten Disord 11, no. 6 (May 2008): 689–99. https://doi.org/10.1177/1087054707305106.
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  - Shanahan, Lilly, William Copeland, E Jane Costello, and Adrian Angold. “Specificity of putative psychosocial risk factors for psychiatric disorders in children and adolescents.” J Child Psychol Psychiatry 49, no. 1 (January 2008): 34–42. https://doi.org/10.1111/j.1469-7610.2007.01822.x.
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  - Bittner, Antje, Helen L. Egger, Alaattin Erkanli, E. Jane Costello, Debra L. Foley, and Adrian Angold. “What do childhood anxiety disorders predict?” J Child Psychol Psychiatry 48, no. 12 (December 2007): 1174–83. https://doi.org/10.1111/j.1469-7610.2007.01812.x.
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  - Copeland, William E., Shari Miller-Johnson, Gordon Keeler, Adrian Angold, and E Jane Costello. “Childhood psychiatric disorders and young adult crime: a prospective, population-based study.” Am J Psychiatry 164, no. 11 (November 2007): 1668–75. https://doi.org/10.1176/appi.ajp.2007.06122026.
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  - Copeland, William E., Gordon Keeler, Adrian Angold, and E Jane Costello. “Traumatic events and posttraumatic stress in childhood.” Arch Gen Psychiatry 64, no. 5 (May 2007): 577–84. https://doi.org/10.1001/archpsyc.64.5.577.
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  - Costello, E Jane, Minje Sung, Carol Worthman, and Adrian Angold. “Pubertal maturation and the development of alcohol use and abuse.” Drug Alcohol Depend 88 Suppl 1 (April 2007): S50–59. https://doi.org/10.1016/j.drugalcdep.2006.12.009.
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  - Costello, E Jane. “Psychiatric predictors of adolescent and young adult drug use and abuse.” Drug Alcohol Depend 88 Suppl 1 (April 2007): S1–3. https://doi.org/10.1016/j.drugalcdep.2006.12.007.
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  - Costello, E Jane. “Psychiatric predictors of adolescent and young adult drug use and abuse: what have we learned?” Drug Alcohol Depend 88 Suppl 1 (April 2007): S97–99. https://doi.org/10.1016/j.drugalcdep.2006.12.027.
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  - Costello, Elizabeth Jane, Carol Worthman, Alaattin Erkanli, and Adrian Angold. “Prediction from low birth weight to female adolescent depression: a test of competing hypotheses.” Arch Gen Psychiatry 64, no. 3 (March 2007): 338–44. https://doi.org/10.1001/archpsyc.64.3.338.
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  - Costello, E Jane, William Copeland, Alexander Cowell, and Gordon Keeler. “Service costs of caring for adolescents with mental illness in a rural community, 1993-2000.” Am J Psychiatry 164, no. 1 (January 2007): 36–42. https://doi.org/10.1176/appi.ajp.2007.164.9.A36.
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  - Phillips, S. D., A. Erkanli, E. J. Costello, and A. Angold. “Differences among children whose mothers have been in contact with the criminal justice system.” Women and Criminal Justice 17, no. 2–3 (2007): 43–61. https://doi.org/10.1300/J012v17n02_04.
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  - Fairbank, J. A., J. S. Klaric, J. M. O’Dekirk, D. W. Fairbank, and E. J. Costello. “Environmental vulnerabilities and posttraumatic stress disorder (PTSD) among children with different personality styles,” December 1, 2006, 35–48.
  - Jane Costello, E., Alaattin Erkanli, and Adrian Angold. “Is there an epidemic of child or adolescent depression?” J Child Psychol Psychiatry 47, no. 12 (December 2006): 1263–71. https://doi.org/10.1111/j.1469-7610.2006.01682.x.
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  - Erkanli, Alaattin, Minje Sung, E Jane Costello, and Adrian Angold. “Bayesian semi-parametric ROC analysis.” Stat Med 25, no. 22 (November 30, 2006): 3905–28. https://doi.org/10.1002/sim.2496.
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  - Brotman, Melissa A., Mariana Schmajuk, Brendan A. Rich, Daniel P. Dickstein, Amanda E. Guyer, E Jane Costello, Helen L. Egger, Adrian Angold, Daniel S. Pine, and Ellen Leibenluft. “Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children.” Biol Psychiatry 60, no. 9 (November 1, 2006): 991–97. https://doi.org/10.1016/j.biopsych.2006.08.042.
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  - Angold, Adrian, and E Jane Costello. “Puberty and depression.” Child Adolesc Psychiatr Clin N Am 15, no. 4 (October 2006): 919–ix. https://doi.org/10.1016/j.chc.2006.05.013.
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  - Costello, Jane. “About papers that are not accepted for publication.” J Child Psychol Psychiatry 47, no. 9 (September 2006): 869–70. https://doi.org/10.1111/j.1469-7610.2006.01683.x.
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  - Foley, Debra L., David B. Goldston, E Jane Costello, and Adrian Angold. “Proximal psychiatric risk factors for suicidality in youth: the Great Smoky Mountains Study.” Arch Gen Psychiatry 63, no. 9 (September 2006): 1017–24. https://doi.org/10.1001/archpsyc.63.9.1017.
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  - Brown, Ryan A., Carol M. Worthman, E Jane Costello, and Alaattin Erkanli. “The Life Trajectory Interview for Youth (LTI-Y): method development and psychometric properties of an instrument to assess life-course models and achievement.” Int J Methods Psychiatr Res 15, no. 4 (2006): 192–206. https://doi.org/10.1002/mpr.195.
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  - Costello, E Jane, Debra L. Foley, and Adrian Angold. “10-year research update review: the epidemiology of child and adolescent psychiatric disorders: II. Developmental epidemiology.” J Am Acad Child Adolesc Psychiatry 45, no. 1 (January 2006): 8–25. https://doi.org/10.1097/01.chi.0000184929.41423.c0.
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  - Costello, J. “Editorial.” Journal of Child Psychology and Psychiatry and Allied Disciplines 47, no. 1 (January 1, 2006): 1–3. https://doi.org/10.1111/j.1469-7610.2005.01605.x.
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  - Rowe, Richard, Barbara Maughan, E Jane Costello, and Adrian Angold. “Defining oppositional defiant disorder.” J Child Psychol Psychiatry 46, no. 12 (December 2005): 1309–16. https://doi.org/10.1111/j.1469-7610.2005.01420.x.
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  - Costello, E Jane, Helen Egger, and Adrian Angold. “10-year research update review: the epidemiology of child and adolescent psychiatric disorders: I. Methods and public health burden.” J Am Acad Child Adolesc Psychiatry 44, no. 10 (October 2005): 972–86. https://doi.org/10.1097/01.chi.0000172552.41596.6f.
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  - Costello, E Jane, Helen L. Egger, and Adrian Angold. “The developmental epidemiology of anxiety disorders: phenomenology, prevalence, and comorbidity.” Child Adolesc Psychiatr Clin N Am 14, no. 4 (October 2005): 631–vii. https://doi.org/10.1016/j.chc.2005.06.003.
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  - Pine, Daniel S., Jane Costello, and Ann Masten. “Trauma, proximity, and developmental psychopathology: the effects of war and terrorism on children.” Neuropsychopharmacology 30, no. 10 (October 2005): 1781–92. https://doi.org/10.1038/sj.npp.1300814.
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  - Costello, J. “Editorial.” Journal of Child Psychology and Psychiatry and Allied Disciplines 46, no. 4 (April 1, 2005): 337–38. https://doi.org/10.1111/j.1469-7610.2005.01455.x.
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  - Costello, E. J., A. Erkanli, G. Keeler, and A. Angold. “Distant Trauma: A prospective study of the effects of september 11th on young adults in North Carolina.” Applied Developmental Science 8, no. 4 (October 1, 2004): 211–20. https://doi.org/10.1207/s1532480xads0804_4.
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  - Eaves, Lindon, Judy Silberg, Debra Foley, Cynthia Bulik, Hermine Maes, Alaattin Erkanli, Adrian Angold, E Jane Costello, and Carol Worthman. “Genetic and environmental influences on the relative timing of pubertal change.” Twin Res 7, no. 5 (October 2004): 471–81. https://doi.org/10.1375/1369052042335278.
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  - Sung, Minje, Al Erkanli, Adrian Angold, and E Jane Costello. “Effects of age at first substance use and psychiatric comorbidity on the development of substance use disorders.” Drug Alcohol Depend 75, no. 3 (September 6, 2004): 287–99. https://doi.org/10.1016/j.drugalcdep.2004.03.013.
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  - Costello, J. “Editorial.” Journal of Child Psychology and Psychiatry and Allied Disciplines 45, no. 5 (July 1, 2004): 897–98. https://doi.org/10.1111/j.1469-7610.2004.t01-1-00283.x.
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  - Rowe, Richard, Barbara Maughan, Carol M. Worthman, E Jane Costello, and Adrian Angold. “Testosterone, antisocial behavior, and social dominance in boys: pubertal development and biosocial interaction.” Biol Psychiatry 55, no. 5 (March 1, 2004): 546–52. https://doi.org/10.1016/j.biopsych.2003.10.010.
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  - Case, Brady. “Effect of poverty on emotional symptoms in children.” Jama 291, no. 4 (January 28, 2004): 424. https://doi.org/10.1001/jama.291.4.424-a.
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  - Costello, E Jane, Scott N. Compton, Gordon Keeler, and Adrian Angold. “Relationships between poverty and psychopathology: a natural experiment.” Jama 290, no. 15 (October 15, 2003): 2023–29. https://doi.org/10.1001/jama.290.15.2023.
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  - Epstein, Jeffery N., Alaatin Erkanli, C Keith Conners, John Klaric, Jane E. Costello, and Adrian Angold. “Relations between Continuous Performance Test performance measures and ADHD behaviors.” J Abnorm Child Psychol 31, no. 5 (October 2003): 543–54. https://doi.org/10.1023/a:1025405216339.
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  - Costello, E Jane, Sarah Mustillo, Alaattin Erkanli, Gordon Keeler, and Adrian Angold. “Prevalence and development of psychiatric disorders in childhood and adolescence.” Arch Gen Psychiatry 60, no. 8 (August 2003): 837–44. https://doi.org/10.1001/archpsyc.60.8.837.
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  - Egger, Helen Link, E Jane Costello, and Adrian Angold. “School refusal and psychiatric disorders: a community study.” J Am Acad Child Adolesc Psychiatry 42, no. 7 (July 2003): 797–807. https://doi.org/10.1097/01.CHI.0000046865.56865.79.
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  - Mustillo, Sarah, Carol Worthman, Alaattin Erkanli, Gordon Keeler, Adrian Angold, and E Jane Costello. “Obesity and psychiatric disorder: developmental trajectories.” Pediatrics 111, no. 4 Pt 1 (April 2003): 851–59. https://doi.org/10.1542/peds.111.4.851.
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  - Farmer, Elizabeth M. Z., Barbara J. Burns, Susan D. Phillips, Adrian Angold, and E Jane Costello. “Pathways into and through mental health services for children and adolescents.” Psychiatr Serv 54, no. 1 (January 2003): 60–66. https://doi.org/10.1176/appi.ps.54.1.60.
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  - Armstrong, Tonya D., and E Jane Costello. “Community studies on adolescent substance use, abuse, or dependence and psychiatric comorbidity.” J Consult Clin Psychol 70, no. 6 (December 2002): 1224–39. https://doi.org/10.1037//0022-006x.70.6.1224.
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  - Angold, Adrian, Alaattin Erkanli, Judy Silberg, Lindon Eaves, and E Jane Costello. “Depression scale scores in 8-17-year-olds: effects of age and gender.” J Child Psychol Psychiatry 43, no. 8 (November 2002): 1052–63. https://doi.org/10.1111/1469-7610.00232.
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  - Angold, Adrian, Alaattin Erkanli, Elizabeth M. Z. Farmer, John A. Fairbank, Barbara J. Burns, Gordon Keeler, and E Jane Costello. “Psychiatric disorder, impairment, and service use in rural African American and white youth.” Arch Gen Psychiatry 59, no. 10 (October 2002): 893–901. https://doi.org/10.1001/archpsyc.59.10.893.
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  - Costello, E Jane, Daniel S. Pine, Constance Hammen, John S. March, Paul M. Plotsky, Myrna M. Weissman, Joseph Biederman, et al. “Development and natural history of mood disorders.” Biol Psychiatry 52, no. 6 (September 15, 2002): 529–42. https://doi.org/10.1016/s0006-3223(02)01372-0.
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  - Costello, E Jane, Alaattin Erkanli, John A. Fairbank, and Adrian Angold. “The prevalence of potentially traumatic events in childhood and adolescence.” J Trauma Stress 15, no. 2 (April 2002): 99–112. https://doi.org/10.1023/A:1014851823163.
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  - Rowe, Richard, Barbara Maughan, Andrew Pickles, E Jane Costello, and Adrian Angold. “The relationship between DSM-IV oppositional defiant disorder and conduct disorder: findings from the Great Smoky Mountains Study.” J Child Psychol Psychiatry 43, no. 3 (March 2002): 365–73. https://doi.org/10.1111/1469-7610.00027.
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  - Ezpeleta, L., G. Keeler, A. Erkanli, E. J. Costello, and A. Angold. “Epidemiology of psychiatric disability in childhood and adolescence.” J Child Psychol Psychiatry 42, no. 7 (October 2001): 901–14. https://doi.org/10.1111/1469-7610.00786.
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  - Costello, E. J., G. P. Keeler, and A. Angold. “Poverty, race/ethnicity, and psychiatric disorder: a study of rural children.” Am J Public Health 91, no. 9 (September 2001): 1494–98. https://doi.org/10.2105/ajph.91.9.1494.
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  - Kaplow, J. B., P. J. Curran, A. Angold, and E. J. Costello. “The prospective relation between dimensions of anxiety and the initiation of adolescent alcohol use.” J Clin Child Psychol 30, no. 3 (September 2001): 316–26. https://doi.org/10.1207/S15374424JCCP3003_4.
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  - Horwitz, S. M., K. Hoagwood, A. R. Stiffman, T. Summerfeld, J. R. Weisz, E. J. Costello, K. Rost, et al. “Reliability of the services assessment for children and adolescents.” Psychiatr Serv 52, no. 8 (August 2001): 1088–94. https://doi.org/10.1176/appi.ps.52.8.1088.
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  - Farmer, E. M. Z., B. J. Burns, M. V. Chapman, S. D. Phillips, A. Angold, and E. J. Costello. “Use of mental health services by youth in contact with social services.” Social Service Review 75, no. 4 (January 1, 2001): 604–24. https://doi.org/10.1086/323165.
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  - Willoughby, M. T., P. J. Curran, E. J. Costello, and A. Angold. “Implications of early versus late onset of attention-deficit/hyperactivity disorder symptoms.” J Am Acad Child Adolesc Psychiatry 39, no. 12 (December 2000): 1512–19. https://doi.org/10.1097/00004583-200012000-00013.
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  - Angold, A., A. Erkanli, H. L. Egger, and E. J. Costello. “Stimulant treatment for children: a community perspective.” J Am Acad Child Adolesc Psychiatry 39, no. 8 (August 2000): 975–84. https://doi.org/10.1097/00004583-200008000-00009.
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  - McDade, T. W., J. F. Stallings, A. Angold, E. J. Costello, M. Burleson, J. T. Cacioppo, R. Glaser, and C. M. Worthman. “Epstein-Barr virus antibodies in whole blood spots: a minimally invasive method for assessing an aspect of cell-mediated immunity.” Psychosom Med 62, no. 4 (July 2000): 560–67. https://doi.org/10.1097/00006842-200007000-00015.
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  - Angold, A., E. J. Costello, B. J. Burns, A. Erkanli, and E. M. Farmer. “Effectiveness of nonresidential specialty mental health services for children and adolescents in the "real world".” J Am Acad Child Adolesc Psychiatry 39, no. 2 (February 2000): 154–60. https://doi.org/10.1097/00004583-200002000-00013.
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  - Angold, A., and E. J. Costello. “The Child and Adolescent Psychiatric Assessment (CAPA).” J Am Acad Child Adolesc Psychiatry 39, no. 1 (January 2000): 39–48. https://doi.org/10.1097/00004583-200001000-00015.
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  - Costello, E. J., and A. Angold. “Developmental psychopathology and public health: past, present, and future.” Dev Psychopathol 12, no. 4 (2000): 599–618. https://doi.org/10.1017/s095457940000403x.
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  - Maughan, B., A. Pickles, R. Rowe, E. J. Costello, and A. Angold. “Developmental Trajectories of Aggressive and Non-Aggressive Conduct Problems.” Journal of Quantitative Criminology 16, no. 2 (January 1, 2000): 199–221. https://doi.org/10.1023/A:1007516622688.
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  - Canino, G., E. J. Costello, and A. Angold. “Assessing Functional Impairment and Social Adaptation for Child Mental Health Services Research: A Review of Measures.” Mental Health Services Research 1, no. 2 (December 1, 1999): 93–108. https://doi.org/10.1023/A:1022334303731.
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  - Erkanli, A., R. Soyer, and E. J. Costello. “Bayesian inference for prevalence in longitudinal two-phase studies.” Biometrics 55, no. 4 (December 1999): 1145–50. https://doi.org/10.1111/j.0006-341x.1999.01145.x.
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  - Angold, A., E. J. Costello, A. Erkanli, and C. M. Worthman. “Pubertal changes in hormone levels and depression in girls.” Psychol Med 29, no. 5 (September 1999): 1043–53. https://doi.org/10.1017/s0033291799008946.
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  - Costello, E. J., A. Erkanli, E. Federman, and A. Angold. “Development of psychiatric comorbidity with substance abuse in adolescents: effects of timing and sex.” J Clin Child Psychol 28, no. 3 (September 1999): 298–311. https://doi.org/10.1207/S15374424jccp280302.
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  - Egger, H. L., E. J. Costello, A. Erkanli, and A. Angold. “Somatic complaints and psychopathology in children and adolescents: stomach aches, musculoskeletal pains, and headaches.” J Am Acad Child Adolesc Psychiatry 38, no. 7 (July 1999): 852–60. https://doi.org/10.1097/00004583-199907000-00015.
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  - Angold, A., E. J. Costello, E. M. Farmer, B. J. Burns, and A. Erkanli. “Impaired but undiagnosed.” J Am Acad Child Adolesc Psychiatry 38, no. 2 (February 1999): 129–37. https://doi.org/10.1097/00004583-199902000-00011.
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  - Costello, E. J., A. Angold, and G. P. Keeler. “Adolescent outcomes of childhood disorders: the consequences of severity and impairment.” J Am Acad Child Adolesc Psychiatry 38, no. 2 (February 1999): 121–28. https://doi.org/10.1097/00004583-199902000-00010.
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  - Farmer, E. M., D. K. Stangl, B. J. Burns, E. J. Costello, and A. Angold. “Use, persistence, and intensity: patterns of care for children's mental health across one year.” Community Ment Health J 35, no. 1 (February 1999): 31–46. https://doi.org/10.1023/a:1018743908617.
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  - Angold, A., E. J. Costello, and A. Erkanli. “Comorbidity.” J Child Psychol Psychiatry 40, no. 1 (January 1999): 57–87.
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  - Jane Costello, E. “Commentary on: Prevalence and impact of parent-reported disabling mental health conditions among U.S. children".” Journal of the American Academy of Child and Adolescent Psychiatry 38, no. 5 (January 1, 1999): 610–13. https://doi.org/10.1097/00004583-199905000-00024.
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  - Costello, E. J., A. Angold, J. March, and J. Fairbank. “Life events and post-traumatic stress: the development of a new measure for children and adolescents.” Psychol Med 28, no. 6 (November 1998): 1275–88. https://doi.org/10.1017/s0033291798007569.
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  - Egger, H. L., A. Angold, and E. J. Costello. “Headaches and psychopathology in children and adolescents.” J Am Acad Child Adolesc Psychiatry 37, no. 9 (September 1998): 951–58. https://doi.org/10.1097/00004583-199809000-00015.
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  - Angold, A., E. J. Costello, and C. M. Worthman. “Puberty and depression: the roles of age, pubertal status and pubertal timing.” Psychol Med 28, no. 1 (January 1998): 51–61. https://doi.org/10.1017/s003329179700593x.
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  - Angold, A., S. C. Messer, D. Stangl, E. M. Farmer, E. J. Costello, and B. J. Burns. “Perceived parental burden and service use for child and adolescent psychiatric disorders.” Am J Public Health 88, no. 1 (January 1998): 75–80. https://doi.org/10.2105/ajph.88.1.75.
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  - Costello, E. J., S. C. Messer, H. R. Bird, P. Cohen, and H. Z. Reinherz. “The prevalence of serious emotional disturbance: A re-analysis of community studies.” Journal of Child and Family Studies 7, no. 4 (January 1, 1998): 411–32. https://doi.org/10.1023/A:1022901909205.
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  - Costello, E. J., E. M. Farmer, A. Angold, B. J. Burns, and A. Erkanli. “Psychiatric disorders among American Indian and white youth in Appalachia: the Great Smoky Mountains Study.” Am J Public Health 87, no. 5 (May 1997): 827–32. https://doi.org/10.2105/ajph.87.5.827.
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  - Federman, E. B., E. J. Costello, A. Angold, E. M. Farmer, and A. Erkanli. “Development of substance use and psychiatric comorbidity in an epidemiologic study of white and American Indian young adolescents the Great Smoky Mountains Study.” Drug Alcohol Depend 44, no. 2–3 (March 14, 1997): 69–78. https://doi.org/10.1016/s0376-8716(96)01317-8.
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  - Angold, A., and E. Jane Costello. “The relative diagnostic utility of child and parent reports of oppositional defiant behaviors.” International Journal of Methods in Psychiatric Research 6, no. 4 (January 1, 1997): 253–59. https://doi.org/10.1002/(sici)1234-988x(199612)6:4<253::aid-mpr170>3.3.co;2-o.
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  - Burns, B. J., E. J. Costello, A. Erkanli, D. L. Tweed, E. M. Z. Farmer, and A. Angold. “Insurance coverage and mental health services use by adolescents with serious emotional disturbance.” Journal of Child and Family Studies 6, no. 1 (January 1, 1997): 89–111. https://doi.org/10.1023/A:1025024808146.
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  - Farmer, E. M. Z., B. J. Burns, A. Angold, and E. J. Costello. “Impact of Children's Mental Health Problems on Families: Relationships with Service Use.” Journal of Emotional and Behavioral Disorders 5, no. 4 (January 1, 1997): 230–38. https://doi.org/10.1177/106342669700500406.
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  - Messer, S. C., A. Angold, E. J. Costello, and B. J. Burns. “The child and adolescent burden assessment (CABA): Measuring the family impact of emotional and behavioral problems.” International Journal of Methods in Psychiatric Research 6, no. 4 (January 1, 1997): 261–84. https://doi.org/10.1002/(sici)1234-988x(199612)6:4<261::aid-mpr169>3.3.co;2-3.
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  - Angold, A., E. J. Costello, and S. C. Messer. “Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents.” International Journal of Methods in Psychiatric Research 5, no. 4 (December 1, 1996): 237–49.
  - Angold, A., J. Costello, W. Van Kämmen, and M. Stouthamer-Loeber. “Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents: factor composition and structure across development.” International Journal of Methods in Psychiatric Research 5, no. 4 (December 1, 1996): 251–62.
  - Costello, E. J., A. Angold, B. J. Burns, D. K. Stangl, D. L. Tweed, A. Erkanli, and C. M. Worthman. “The Great Smoky Mountains Study of Youth. Goals, design, methods, and the prevalence of DSM-III-R disorders.” Arch Gen Psychiatry 53, no. 12 (December 1996): 1129–36. https://doi.org/10.1001/archpsyc.1996.01830120067012.
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  - Angold, A., A. Erkanli, E. J. Costello, and M. Rutter. “Precision, reliability and accuracy in the dating of symptom onsets in child and adolescent psychopathology.” J Child Psychol Psychiatry 37, no. 6 (September 1996): 657–64. https://doi.org/10.1111/j.1469-7610.1996.tb01457.x.
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  - Angold, A., and E. J. Costello. “Toward establishing an empirical basis for the diagnosis of oppositional defiant disorder.” J Am Acad Child Adolesc Psychiatry 35, no. 9 (September 1996): 1205–12. https://doi.org/10.1097/00004583-199609000-00018.
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  - Bristol, M. M., D. J. Cohen, E. J. Costello, M. Denckla, T. J. Eckberg, R. Kallen, H. C. Kraemer, et al. “State of the science in autism: report to the National Institutes Health.” J Autism Dev Disord 26, no. 2 (April 1996): 121–54. https://doi.org/10.1007/BF02172002.
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  - Angold, A., A. Erkanli, R. Loebkr, E. J. Costello, W. Van Kammen, and M. Stouthamer-Loeber. “Disappearing Depression in a Population Sample of Boys.” Journal of Emotional and Behavioral Disorders 4, no. 2 (January 1, 1996): 95–104. https://doi.org/10.1177/106342669600400204.
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  - Angold, A., and E. J. Costello. “A test-retest reliability study of child-reported psychiatric symptoms and diagnoses using the Child and Adolescent Psychiatric Assessment (CAPA-C).” Psychol Med 25, no. 4 (July 1995): 755–62. https://doi.org/10.1017/s0033291700034991.
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  - Angold, A., and E. J. Costello. “Developmental epidemiology.” Epidemiol Rev 17, no. 1 (1995): 74–82. https://doi.org/10.1093/oxfordjournals.epirev.a036187.
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  - Burns, B. J., E. J. Costello, A. Angold, D. Tweed, D. Stangl, E. M. Farmer, and A. Erkanli. “Children's mental health service use across service sectors.” Health Aff (Millwood) 14, no. 3 (1995): 147–59. https://doi.org/10.1377/hlthaff.14.3.147.
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  - Costello, E. J., B. J. Burns, A. Angold, and P. J. Leaf. “Epidemiology and health care reform.” J Am Acad Child Adolesc Psychiatry 33, no. 7 (September 1994): 1058–59. https://doi.org/10.1097/00004583-199409000-00020.
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  - Farmer, E. M. Z., A. Angold, B. J. Burns, and E. J. Costello. “Reliability of self-reported service use: Test-retest consistency of children's responses to the Child and Adolescent Services Assessment (CASA).” Journal of Child and Family Studies 3, no. 3 (September 1, 1994): 307–25. https://doi.org/10.1007/BF02234688.
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  - Angold, A., and E. J. Costello. “Depressive comorbidity in children and adolescents: empirical, theoretical, and methodological issues.” Am J Psychiatry 150, no. 12 (December 1993): 1779–91. https://doi.org/10.1176/ajp.150.12.1779.
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  - Costello, E. J., B. J. Burns, A. Angold, and P. J. Leaf. “How can epidemiology improve mental health services for children and adolescents?” J Am Acad Child Adolesc Psychiatry 32, no. 6 (November 1993): 1106–14. https://doi.org/10.1097/00004583-199311000-00002.
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  - Costello, E. J., and A. Angold. “Toward a developmental epidemiology of the disruptive behavior disorders.” Development and Psychopathology 5, no. 1–2 (January 1, 1993): 91–101. https://doi.org/10.1017/S0954579400004284.
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  - Bromberger, J. T., and E. J. Costello. “Epidemiology of depression for clinicians.” Soc Work 37, no. 2 (March 1992): 120–25.
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  - Costello, E. J., and M. A. Shugart. “Above and below the threshold: Severity of psychiatric symptoms and functional impairment in a pediatric sample.” Pediatrics 90, no. 3 I (January 1, 1992): 359–68.
  - Costello, E. J., R. Benjamin, A. Angold, and D. Silver. “Mood variability in adolescents: a study of depressed, nondepressed and comorbid patients.” J Affect Disord 23, no. 4 (December 1991): 199–212. https://doi.org/10.1016/0165-0327(91)90101-w.
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  - Costello, E. J. “Married with children: predictors of mental and physical health in middle-aged women.” Psychiatry 54, no. 3 (August 1991): 292–305. https://doi.org/10.1080/00332747.1991.11024558.
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  - Costello, E. J., R. Loeber, and M. Stouthamer-Loeber. “Pervasive and situational hyperactivity--confounding effect of informant: a research note.” J Child Psychol Psychiatry 32, no. 2 (January 1991): 367–76. https://doi.org/10.1111/j.1469-7610.1991.tb00313.x.
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  - Costello, E. J., and M. A. Shugart. “Child mental health and primary pediatric care.” Current Opinion in Pediatrics 3, no. 4 (January 1, 1991): 636–41. https://doi.org/10.1097/00008480-199108000-00012.
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  - Costello, E. J., and S. Janiszewski. “Who gets treated? Factors associated with referral in children with psychiatric disorders.” Acta Psychiatr Scand 81, no. 6 (June 1990): 523–29. https://doi.org/10.1111/j.1600-0447.1990.tb05492.x.
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  - Dulcan, M. K., E. J. Costello, A. J. Costello, C. Edelbrock, D. Brent, and S. Janiszewski. “The pediatrician as gatekeeper to mental health care for children: do parents' concerns open the gate?” J Am Acad Child Adolesc Psychiatry 29, no. 3 (May 1990): 453–58. https://doi.org/10.1097/00004583-199005000-00018.
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  - Benjamin, R. S., E. J. Costello, and M. Warren. “Anxiety disorders in a pediatric sample.” Journal of Anxiety Disorders 4, no. 4 (January 1, 1990): 293–316. https://doi.org/10.1016/0887-6185(90)90027-7.
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  - Benjamin, R. S., E. J. Costello, and M. Warren. “Anxiety disorders in a pediatric sample.” Journal of Anxiety Disorders 4, no. 4 (1990): 293–316.
  - Costello, E. J. “In Reply.” Archives of General Psychiatry 47, no. 1 (January 1, 1990): 89–90. https://doi.org/10.1001/archpsyc.1990.01810130091013.
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  - Matthews, K. A., R. R. Wing, L. H. Kuller, E. N. Meilahn, S. F. Kelsey, E. J. Costello, and A. W. Caggiula. “Influences of Natural Menopause on Psychological Characteristics and Symptoms of Middle-Aged Healthy Women.” Journal of Consulting and Clinical Psychology 58, no. 3 (January 1, 1990): 345–51. https://doi.org/10.1037/0022-006X.58.3.345.
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  - Costello, E. J. “Child psychiatric disorders and their correlates: a primary care pediatric sample.” J Am Acad Child Adolesc Psychiatry 28, no. 6 (November 1989): 851–55. https://doi.org/10.1097/00004583-198911000-00007.
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  - Costello, E. J. “Developments in child psychiatric epidemiology.” J Am Acad Child Adolesc Psychiatry 28, no. 6 (November 1989): 836–41. https://doi.org/10.1097/00004583-198911000-00004.
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  - Costello, E. J. “More on treated incidence data.” J Am Acad Child Adolesc Psychiatry 28, no. 5 (September 1989): 803–4. https://doi.org/10.1097/00004583-198909000-00031.
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  - Costello, E. J. “The utility of care: Behavioral decision analysis and the development of depression.” Development and Psychopathology 1, no. 1 (January 1, 1989): 69–89. https://doi.org/10.1017/S0954579400000250.
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  - Costello, E. J., A. J. Costello, C. Edelbrock, B. J. Burns, M. K. Dulcan, D. Brent, and S. Janiszewski. “Psychiatric disorders in pediatric primary care. Prevalence and risk factors.” Arch Gen Psychiatry 45, no. 12 (December 1988): 1107–16. https://doi.org/10.1001/archpsyc.1988.01800360055008.
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  - Costello, E. J., and A. Angold. “Scales to assess child and adolescent depression: checklists, screens, and nets.” J Am Acad Child Adolesc Psychiatry 27, no. 6 (November 1988): 726–37. https://doi.org/10.1097/00004583-198811000-00011.
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  - Costello, E. J., B. J. Burns, A. J. Costello, C. Edelbrock, M. Dulcan, and D. Brent. “Service utilization and psychiatric diagnosis in pediatric primary care: The role of the gatekeeper.” Pediatrics 82, no. 3 II (January 1, 1988): 435–41.
  - Costello, E. J., C. Edelbrock, A. J. Costello, M. K. Dulcan, B. J. Burns, and D. Brent. “Psychopathology in pediatric primary care: The new hidden morbidity.” Pediatrics 82, no. 3 II (January 1, 1988): 415–24.
  - Costello, E. J., and T. Pantino. “The new morbidity: who should treat it?” J Dev Behav Pediatr 8, no. 5 (October 1987): 288–91.
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  - Costello, E. J. “Primary care pediatrics and child psychopathology: a review of diagnostic, treatment, and referral practices.” Pediatrics 78, no. 6 (December 1986): 1044–51.
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  - Costello, E. J., C. S. Edelbrock, and A. J. Costello. “Validity of the NIMH Diagnostic Interview Schedule for Children: a comparison between psychiatric and pediatric referrals.” J Abnorm Child Psychol 13, no. 4 (December 1985): 579–95. https://doi.org/10.1007/BF00923143.
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  - Costello, E. J., and C. S. Edelbrock. “Detection of psychiatric disorders in pediatric primary care: a preliminary report.” J Am Acad Child Psychiatry 24, no. 6 (November 1985): 771–74. https://doi.org/10.1016/s0002-7138(10)60122-7.
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  - Costello, E. J. “Information processing for decision making in depressed women. A study of subjective expected utilities.” J Affect Disord 5, no. 3 (August 1983): 239–51. https://doi.org/10.1016/0165-0327(83)90047-2.
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  - Costello, E. J. “Locus of control and depression in students and psychiatric outpatients.” J Clin Psychol 38, no. 2 (April 1982): 340–43. https://doi.org/10.1002/1097-4679(198204)38:2<340::aid-jclp2270380220>3.0.co;2-d.
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- Book Sections
  - Costello, E. J., and A. Angold. “Developmental Epidemiology.” In Developmental Psychopathology: Second Edition, 1:41–75, 2015. https://doi.org/10.1002/9780470939383.ch3.
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  - Loeber, R., D. M. Capaldi, and E. Costello. “Gender and the development of aggression, disruptive behavior, and delinquency from childhood to early adulthood.” In Disruptive Behavior Disorders, 137–60, 2013. https://doi.org/10.1007/978-1-4614-7557-6_6.
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  - Costello, E. J., H. L. Egger, W. Copeland, A. Erkanli, and A. Angold. “The developmental epidemiology of anxiety disorders: Phenomenology, prevalence, and comorbidity.” In Anxiety Disorders in Children and Adolescents, Second Edition, 56–75, 2011. https://doi.org/10.1017/CBO9780511994920.004.
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  - Costello, E. J. “Phobias in Childhood and Adolescence: Implications for Public Policy.” In Phobias, 7:297–99, 2005. https://doi.org/10.1002/0470014113.ch5.
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  - Angold, A., W. Carol, and E. J. Costello. “Puberty and depression.” In Gender Differences at Puberty, 137–64, 2003. https://doi.org/10.1017/CBO9780511489716.009.
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Scholarly, Clinical, & Service Activities
Presentations & Appearances
- Prevention of early psychiatric and substance use disorders. July 31, 2009 2009
- Preventing mental, emotional, and behavioral disorders among young people: progress and possibilities. February 1, 2009 2009

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