Scholars@Duke
Elizabeth Jane Costello

Elizabeth Jane Costello

Professor Emerita in Psychiatry and Behavioral Sciences
Psychiatry, Child & Family Mental Health & Community Psychiatry
jcostell@psych.mc.duke.edu
Box 3454 Med Ctr, Durham, NC 27710
Brightleaf SQ Ste 22, 905 W Main St, Durham, NC 27701

Selected Publications

Long-term Outcomes of Childhood Family Income Supplements on Adult Functioning.

Journal Article JAMA Pediatr · October 1, 2022 IMPORTANCE: During an ongoing longitudinal cohort study, a casino opening created a natural cash transfer experiment. Some participating families received income supplements, and others did not. The children in this study are now adults. OBJECTIVE: To asse ... Full text Link to item Cite

From Birth in a British Orphanage to Assessments of American Indians’ Development

Chapter · January 1, 2021 Jane Costello, Professor Emerita of Psychiatry and Behavioral Sciences at Duke University (United States) was born in England (1939) and received her PhD in social psychology from the University of London School of Economics. She participated in two Nation ... Full text Cite

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium.

Journal Article Mol Psychiatry · August 2020 To provide insights into the biology of opioid dependence (OD) and opioid use (i.e., exposure, OE), we completed a genome-wide analysis comparing 4503 OD cases, 4173 opioid-exposed controls, and 32,500 opioid-unexposed controls, including participants of E ... Full text Link to item Cite

Associations of Despair With Suicidality and Substance Misuse Among Young Adults.

Journal Article JAMA Netw Open · June 1, 2020 IMPORTANCE: Deaths of despair is a term that has recently been used to describe the increases in premature mortality from suicides, drug overdoses (particularly from opiates), and alcohol-related liver disease among US adults. Despite the use of the term d ... Full text Link to item Cite

Income dividends and subjective survival in a Cherokee Indian cohort: a quasi-experiment.

Journal Article Biodemography and social biology · April 2020 Persons with high temporal discounting tend to value immediate gratification over future gains. Low self-reported lifespan (SRL)-an individual's assessment of a relatively short future lifespan-concentrates in low-income populations and may reflect high te ... Full text Cite

Early Pubertal Timing and Testosterone Associated With Higher Levels of Adolescent Depression in Girls.

Journal Article J Am Acad Child Adolesc Psychiatry · December 2019 OBJECTIVE: The prevalence of depression increases dramatically during puberty in girls. Earlier work in this sample reported that the sex steroids estradiol and testosterone were associated with increased depression in girls. Using three additional data wa ... Full text Link to item Cite

Association of Parental Incarceration With Psychiatric and Functional Outcomes of Young Adults.

Journal Article JAMA Netw Open · August 2, 2019 IMPORTANCE: In 2016, an estimated 8% of US children younger than 18 years had experienced the incarceration of a parent, and rates were substantially higher among children from racial and ethnic minority backgrounds and disadvantaged groups. Little is know ... Full text Open Access Link to item Cite

Does Despair Really Kill? A Roadmap for an Evidence-Based Answer.

Journal Article Am J Public Health · June 2019 Two seemingly associated demographic trends have generated considerable interest: income stagnation and rising premature mortality from suicides, drug poisoning, and alcoholic liver disease among US non-Hispanic Whites with low education. Economists interp ... Full text Link to item Cite

Association of Childhood Trauma Exposure With Adult Psychiatric Disorders and Functional Outcomes.

Journal Article JAMA Netw Open · November 2, 2018 IMPORTANCE: Being exposed to trauma is a common childhood experience associated with symptoms and impairments in childhood. OBJECTIVE: To assess the association between cumulative childhood trauma exposure and adult psychiatric and functional outcomes. DES ... Full text Link to item Cite

Self- and parent-reported depressive symptoms rated by the mood and feelings questionnaire.

Journal Article Psychiatry Res · October 2018 The Mood and Feelings Questionnaire (MFQ) was developed to measure depressive symptoms in children and adolescents. It includes a self-report and a parent-report part. This study set out to test the psychometric properties of the MFQ in a Danish population ... Full text Link to item Cite

How Does Household Income Affect Child Personality Traits and Behaviors?

Journal Article Am Econ Rev · March 2018 We examine the effects of a quasi-experimental unconditional household income transfer on child emotional and behavioral health and personality traits. Using longitudinal data, we find that there are large beneficial effects on children's emotional and beh ... Full text Link to item Cite

Predicting Persistent, Limited, and Delayed Problematic Cannabis Use in Early Adulthood: Findings From a Longitudinal Study.

Journal Article J Am Acad Child Adolesc Psychiatry · November 2017 OBJECTIVE: To identify risk profiles associated with patterns of problematic cannabis use in early adulthood. METHOD: Data came from 1,229 participants in the Great Smoky Mountains Study, a prospective 20-year cohort study from 1993 to 2015 that is represe ... Full text Link to item Cite

Adult Associations of Childhood Suicidal Thoughts and Behaviors: A Prospective, Longitudinal Analysis.

Journal Article J Am Acad Child Adolesc Psychiatry · November 2017 OBJECTIVE: Suicidal thoughts and behavior (STBs) have their peak period of onset in adolescence, but little is known about how such behavior is associated with later functioning. The aim of this study is to test whether childhood STBs are related to adult ... Full text Link to item Cite

Deep Sequencing of 71 Candidate Genes to Characterize Variation Associated with Alcohol Dependence.

Journal Article Alcohol Clin Exp Res · April 2017 BACKGROUND: Previous genomewide association studies (GWASs) have identified a number of putative risk loci for alcohol dependence (AD). However, only a few loci have replicated and these replicated variants only explain a small proportion of AD risk. Using ... Full text Link to item Cite

Cannabis Use and Disorder From Childhood to Adulthood in a Longitudinal Community Sample With American Indians.

Journal Article J Am Acad Child Adolesc Psychiatry · February 2017 OBJECTIVE: Recent changes in DSM criteria require new documentation of the prevalence and developmental sequences of cannabis use disorder (CUD). The goal of this study was to investigate the early course of DSM-5 CUD and its overlap with DSM-IV and consum ... Full text Link to item Cite

Use, Persistence, and Intensity: Patterns of Care for Children’s Mental Health Across One Year

Chapter · January 1, 2017 This paper explores the use, persistence, and intensity of services for children’s mental health problems across a variety of service sectors during a one year period. Data come from the Great Smoky Mountains Study. Analyses focus on children’s psychiatric ... Full text Cite

The Great Smoky Mountains Study: developmental epidemiology in the southeastern United States.

Journal Article Soc Psychiatry Psychiatr Epidemiol · May 2016 AIMS: To describe the Great Smoky Mountains Study (GSMS). METHODS: GSMS is a longitudinal study of child psychiatric disorders that began in 1992 to look at need for mental health services in a rural area of the USA. Over 20 years it has expanded its range ... Full text Link to item Cite

Early Detection and Prevention of Mental Health Problems: Developmental Epidemiology and Systems of Support.

Journal Article J Clin Child Adolesc Psychol · 2016 This article reviews the role of developmental epidemiology in the prevention of child and adolescent mental disorders and the implications for systems of support. The article distinguishes between universal or primary prevention, which operates at the lev ... Full text Link to item Cite

Does childhood bullying predict eating disorder symptoms? A prospective, longitudinal analysis.

Journal Article Int J Eat Disord · December 2015 OBJECTIVE: Bullying is a common childhood experience with enduring psychosocial consequences. The aim of this study was to test whether bullying increases risk for eating disorder symptoms. METHOD: Ten waves of data on 1,420 participants between ages 9 and ... Full text Link to item Cite

Developmental Epidemiology

Chapter · September 8, 2015 This chapter discusses developmental psychopathology from the viewpoint of epidemiology, "the study of health and illness in human populations". After a brief introduction to some of the basic concepts of the epidemiological method, it discusses what moder ... Full text Cite

Adult Functional Outcomes of Common Childhood Psychiatric Problems: A Prospective, Longitudinal Study.

Journal Article JAMA Psychiatry · September 2015 IMPORTANCE: Psychiatric problems are among the most common health problems of childhood. OBJECTIVE: To test whether these health problems adversely affect adult functioning even if the problems themselves do not persist. DESIGN, SETTING, AND PARTICIPANTS: ... Full text Link to item Cite

Genome-Wide Meta-Analysis of Longitudinal Alcohol Consumption Across Youth and Early Adulthood.

Journal Article Twin Res Hum Genet · August 2015 The public health burden of alcohol is unevenly distributed across the life course, with levels of use, abuse, and dependence increasing across adolescence and peaking in early adulthood. Here, we leverage this temporal patterning to search for common gene ... Full text Link to item Cite

Normative Irritability in Youth: Developmental Findings From the Great Smoky Mountains Study.

Journal Article J Am Acad Child Adolesc Psychiatry · August 2015 OBJECTIVE: The goal of this study is to examine the developmental epidemiology of normative irritability and its tonic and phasic components in a longitudinal community sample of youth. METHOD: Eight waves of data from the prospective, community Great Smok ... Full text Link to item Cite

Childhood somatic complaints predict generalized anxiety and depressive disorders during young adulthood in a community sample.

Journal Article Psychol Med · June 2015 BACKGROUND: Children with somatic complaints are at increased risk for emotional disorders during childhood. Whether this elevated risk extends into young adulthood - and to which specific disorders - has rarely been tested with long-term prospective-longi ... Full text Link to item Cite

Adult mental health consequences of peer bullying and maltreatment in childhood: two cohorts in two countries.

Journal Article Lancet Psychiatry · June 2015 BACKGROUND: The adult mental health consequences of childhood maltreatment are well documented. Maltreatment by peers (ie, bullying) has also been shown to have long-term adverse effects. We aimed to determine whether these effects are just due to being ex ... Full text Link to item Cite

A heavy burden on young minds: the global burden of mental and substance use disorders in children and youth.

Journal Article Psychol Med · May 2015 BACKGROUND: Mental and substance use disorders are common and often persistent, with many emerging in early life. Compared to adult mental and substance use disorders, the global burden attributable to these disorders in children and youth has received rel ... Full text Link to item Cite

Increase in untreated cases of psychiatric disorders during the transition to adulthood.

Journal Article Psychiatr Serv · April 1, 2015 OBJECTIVE: During the transition to adulthood, youths face challenges that may limit their likelihood of obtaining services for psychiatric problems. The goal of this analysis was to estimate changes in rates of service use and untreated psychiatric disord ... Full text Link to item Cite

Annual research review: Optimal outcomes of child and adolescent mental illness.

Journal Article J Child Psychol Psychiatry · March 2015 BACKGROUND: 'Optimal outcomes' of child and adolescent psychiatric disorders may mean the best possible outcome, or the best considering a child's history. Most research into the outcomes of child and adolescent psychiatric disorder concentrates on the lik ... Full text Link to item Cite

Are children and adolescents with food allergies at increased risk for psychopathology?

Journal Article J Psychosom Res · December 2014 OBJECTIVE: Living with food allergy is a unique and potentially life-threatening stressor that requires constant vigilance to food-related stimuli, but little is known about whether adolescents with food allergies are at increased risk for psychopathology- ... Full text Link to item Cite

Adult diagnostic and functional outcomes of DSM-5 disruptive mood dysregulation disorder.

Journal Article Am J Psychiatry · June 2014 OBJECTIVE: Disruptive mood dysregulation disorder (DMDD) is a new disorder for DSM-5 that is uncommon and frequently co-occurs with other psychiatric disorders. Here, the authors test whether meeting diagnostic criteria for this disorder in childhood predi ... Full text Link to item Cite

Childhood bullying involvement predicts low-grade systemic inflammation into adulthood.

Journal Article Proc Natl Acad Sci U S A · May 27, 2014 Bullying is a common childhood experience that involves repeated mistreatment to improve or maintain one's status. Victims display long-term social, psychological, and health consequences, whereas bullies display minimal ill effects. The aim of this study ... Full text Open Access Link to item Cite

Sleep problems predict and are predicted by generalized anxiety/depression and oppositional defiant disorder.

Journal Article J Am Acad Child Adolesc Psychiatry · May 2014 OBJECTIVE: We tested whether sleep problems co-occur with, precede, and/or follow common psychiatric disorders during childhood and adolescence. We also clarified the role of comorbidity and tested for specificity of associations among sleep problems and p ... Full text Link to item Cite

Services for adolescents with psychiatric disorders: 12-month data from the National Comorbidity Survey-Adolescent.

Journal Article Psychiatr Serv · March 1, 2014 OBJECTIVE: This study examined 12-month rates of service use for mental, emotional, and behavioral disorders among adolescents. METHODS: Data were from the National Comorbidity Survey Adolescent Supplement (NCS-A), a survey of DSM-IV mental, emotional, and ... Full text Link to item Cite

Longitudinal patterns of anxiety from childhood to adulthood: the Great Smoky Mountains Study.

Journal Article J Am Acad Child Adolesc Psychiatry · January 2014 OBJECTIVE: The aims of this study were 2-fold: to provide a brief introduction to the prospective longitudinal Great Smoky Mountains Study and review recent findings; and to use this sample to conduct an epidemiologic analysis of common childhood anxiety d ... Full text Link to item Cite

Estimating the causal effect of conduct disorder on the time from first substance use to substance use disorders using g-estimation.

Journal Article Subst Abus · 2014 BACKGROUND: The effect of conduct disorder (CD) as a major risk factor of substance use disorder (SUD), controlling for other psychiatric problems, has been well established in the literature. However, other psychiatric problems are associated as confounde ... Full text Link to item Cite

Preschool anxiety disorders in pediatric primary care: prevalence and comorbidity.

Journal Article J Am Acad Child Adolesc Psychiatry · December 2013 OBJECTIVE: We sought to establish prevalence rates and detail patterns of comorbidity for generalized anxiety disorder, separation anxiety disorder, and social phobia in preschool-aged children. METHOD: The Duke Preschool Anxiety Study, a screen-stratified ... Full text Link to item Cite

C-reactive protein and substance use disorders in adolescence and early adulthood: a prospective analysis.

Journal Article Drug Alcohol Depend · December 1, 2013 BACKGROUND: Dysregulated immune function and elevated inflammation markers are seen in adults with chronic diseases, including some psychiatric disorders, but evidence on inflammation in the case of drug abuse is conflicting. OBJECTIVE: To test the concurr ... Full text Link to item Cite

Children with both asthma and depression are at risk for heightened inflammation.

Journal Article J Pediatr · November 2013 OBJECTIVE: To test whether children and adolescents with co-occurring asthma and depression are at risk for elevated inflammation-concurrently and at the next assessment. STUDY DESIGN: Up to 6 yearly assessments per person from the prospective, population- ... Full text Link to item Cite

Sex-differentiated changes in C-reactive protein from ages 9 to 21: the contributions of BMI and physical/sexual maturation.

Journal Article Psychoneuroendocrinology · October 2013 BACKGROUND: Sex differences in levels of C-reactive protein (CRP) are well established in adulthood, but little is known about when and why they emerge. Here, we tested longitudinal models of CRP levels from ages 9 to 21, when marked physical and behaviora ... Full text Link to item Cite

Impact of bullying in childhood on adult health, wealth, crime, and social outcomes.

Journal Article Psychol Sci · October 2013 Bullying is a serious problem for schools, parents, and public-policymakers alike. Bullying creates risks of health and social problems in childhood, but it is unclear if such risks extend into adulthood. A large cohort of children was assessed for bullyin ... Full text Link to item Cite

Irritable mood as a symptom of depression in youth: prevalence, developmental, and clinical correlates in the Great Smoky Mountains Study.

Journal Article J Am Acad Child Adolesc Psychiatry · August 2013 OBJECTIVE: DSM-IV grants episodic irritability an equal status to low mood as a cardinal criterion for the diagnosis of depression in youth, yet not in adults; however, evidence for irritability as a major criterion of depression in youth is lacking. This ... Full text Link to item Cite

Diagnostic transitions from childhood to adolescence to early adulthood.

Journal Article J Child Psychol Psychiatry · July 2013 BACKGROUND: Quantifying diagnostic transitions across development is needed to estimate the long-term burden of mental illness. This study estimated patterns of diagnostic transitions from childhood to adolescence and from adolescence to early adulthood. M ... Full text Link to item Cite

School mental health resources and adolescent mental health service use.

Journal Article J Am Acad Child Adolesc Psychiatry · May 2013 OBJECTIVE: Although schools are identified as critical for detecting youth mental disorders, little is known about whether the number of mental health providers and types of resources that they offer influence student mental health service use. Such inform ... Full text Link to item Cite

High quality methylome-wide investigations through next-generation sequencing of DNA from a single archived dry blood spot.

Journal Article Epigenetics · May 2013 The potential importance of DNA methylation in the etiology of complex diseases has led to interest in the development of methylome-wide association studies (MWAS) aimed at interrogating all methylation sites in the human genome. When using blood as biomat ... Full text Link to item Cite

Genes, environments, and developmental research: methods for a multi-site study of early substance abuse.

Journal Article Twin Res Hum Genet · April 2013 The importance of including developmental and environmental measures in genetic studies of human pathology is widely acknowledged, but few empirical studies have been published. Barriers include the need for longitudinal studies that cover relevant develop ... Full text Link to item Cite

Young Adult Obesity and Household Income: Effects of Unconditional Cash Transfers.

Journal Article Am Econ J Appl Econ · April 1, 2013 We investigate the effect of household cash transfers during childhood on young adult body mass indexes (BMI). The effects of extra income differ depending on the household's initial socioeconomic status (SES). Children from the initially poorest household ... Full text Link to item Cite

Adult psychiatric outcomes of bullying and being bullied by peers in childhood and adolescence.

Journal Article JAMA Psychiatry · April 2013 IMPORTANCE: Both bullies and victims of bullying are at risk for psychiatric problems in childhood, but it is unclear if this elevated risk extends into early adulthood. OBJECTIVE: To test whether bullying and/or being bullied in childhood predicts psychia ... Full text Link to item Cite

Prevalence, comorbidity, and correlates of DSM-5 proposed disruptive mood dysregulation disorder.

Journal Article Am J Psychiatry · February 2013 OBJECTIVE: No empirical studies on the DSM-5 proposed disruptive mood dysregulation disorder have yet been published. This study estimated prevalence, comorbidity, and correlates of this proposed disorder in the community. METHOD: Prevalence rates were est ... Full text Link to item Cite

Indirect comorbidity in childhood and adolescence.

Journal Article Front Psychiatry · 2013 OBJECTIVE: Comorbidity between psychiatric disorders is common, but pairwise associations between two disorders may be explained by the presence of other diagnoses that are associated with both disorders or "indirect" comorbidity. MATERIALS AND METHODS: Co ... Full text Link to item Cite

Generalized anxiety and C-reactive protein levels: a prospective, longitudinal analysis.

Journal Article Psychol Med · December 2012 BACKGROUND: Generalized anxiety disorder (GAD) is highly co-morbid with depression. Depression is associated with elevated levels of the inflammation marker C-reactive protein (CRP), cross-sectionally and over time. To date, no studies have looked at the a ... Full text Link to item Cite

Food insecurity and mental disorders in a national sample of U.S. adolescents.

Journal Article J Am Acad Child Adolesc Psychiatry · December 2012 OBJECTIVE: To examine whether food insecurity is associated with past-year DSM-IV mental disorders after controlling for standard indicators of family socioeconomic status (SES) in a U.S. national sample of adolescents. METHOD: Data were drawn from 6,483 a ... Full text Link to item Cite

Predicting persistent alcohol problems: a prospective analysis from the Great Smoky Mountain Study.

Journal Article Psychol Med · September 2012 BACKGROUND: Rates of alcohol disorders peak in late adolescence and decrease substantially into the mid-20s. Our aim was to identify risk factors that predict alcohol problems that persist into the mid-20s. METHOD: Data are from the prospective, population ... Full text Link to item Cite

Socioeconomic status and adolescent mental disorders.

Journal Article Am J Public Health · September 2012 OBJECTIVES: Although previous research has shown that low socioeconomic status (SES) is associated with mental illness, it is unclear which aspects of SES are most important. We investigated this issue by examining associations between 5 aspects of SES and ... Full text Link to item Cite

Psychiatric diagnostic interviews for children and adolescents: a comparative study.

Journal Article J Am Acad Child Adolesc Psychiatry · May 2012 OBJECTIVE: To compare examples of three styles of psychiatric interviews for youth: the Diagnostic Interview Schedule for Children (DISC) ("respondent-based"), the Child and Adolescent Psychiatric Assessment (CAPA) ("interviewer-based"), and the Developmen ... Full text Link to item Cite

Severity of 12-month DSM-IV disorders in the National Comorbidity Survey Replication Adolescent Supplement.

Journal Article Arch Gen Psychiatry · April 2012 CONTEXT: Estimates of DSM-IV disorder prevalence are high; stringent criteria to define need for services are desired. OBJECTIVE: To present US national data on the prevalence and sociodemographic correlates of 12-month serious emotional disturbance (SED), ... Full text Link to item Cite

Prevalence, persistence, and sociodemographic correlates of DSM-IV disorders in the National Comorbidity Survey Replication Adolescent Supplement.

Journal Article Arch Gen Psychiatry · April 2012 CONTEXT: Community epidemiological data on the prevalence and correlates of adolescent mental disorders are needed for policy planning purposes. Only limited data of this sort are available. OBJECTIVE: To present estimates of 12-month and 30-day prevalence ... Full text Link to item Cite

Cumulative depression episodes predict later C-reactive protein levels: a prospective analysis.

Journal Article Biol Psychiatry · January 1, 2012 BACKGROUND: Depression is associated with elevated levels of the inflammation marker C-reactive protein (CRP); yet, the direction of this association remains unclear. This study tested bi-directional longitudinal associations between CRP and depression in ... Full text Link to item Cite

Child-, adolescent- and young adult-onset depressions: differential risk factors in development?

Journal Article Psychol Med · November 2011 BACKGROUND: Previous research reported that childhood adversity predicts juvenile- onset but not adult-onset depression, but studies confounded potentially genuine differences in adversity with differences in the recency with which adversity was experience ... Full text Link to item Cite

Overlooked and underserved: "action signs" for identifying children with unmet mental health needs.

Journal Article Pediatrics · November 2011 OBJECTIVE: The US Surgeon General has called for new approaches to close the mental health services gap for the large proportion of US children with significant mental health needs who have not received evaluation or services within the previous 6 to 12 mo ... Full text Link to item Cite

Trends in psychopathology across the adolescent years: what changes when children become adolescents, and when adolescents become adults?

Journal Article J Child Psychol Psychiatry · October 2011 BACKGROUND: Little is known about changes in the prevalence of psychiatric disorders between childhood and adolescence, and adolescence and adulthood. METHODS: We reviewed papers reporting prevalence rates of psychiatric disorders separately for childhood, ... Full text Link to item Cite

Child ÎĽ-opioid receptor gene variant influences parent-child relations.

Journal Article Neuropsychopharmacology · May 2011 Variation in the ÎĽ-opioid receptor gene has been associated with early social behavior in mice and rhesus macaques. The current study tested whether the functional OPRM1 A118G predicted various indices of social relations in children. The sample included 2 ... Full text Link to item Cite

Cumulative prevalence of psychiatric disorders by young adulthood: a prospective cohort analysis from the Great Smoky Mountains Study.

Journal Article J Am Acad Child Adolesc Psychiatry · March 2011 OBJECTIVE: No longitudinal studies beginning in childhood have estimated the cumulative prevalence of psychiatric illness from childhood into young adulthood. The objective of this study was to estimate the cumulative prevalence of psychiatric disorders by ... Full text Link to item Cite

The developmental epidemiology of anxiety disorders: Phenomenology, prevalence, and comorbidity

Chapter · January 1, 2011 In this chapter we review the prevalence and comorbidity of anxiety disorders in general, and where possible the specifics of separation anxiety disorder (SAD), generalized anxiety disorder (GAD), specific phobias, panic, social phobia, and panic disorder. ... Full text Cite

Developmental pathways in oppositional defiant disorder and conduct disorder.

Journal Article J Abnorm Psychol · November 2010 The Diagnostic and Statistical Manual of Mental Disorders, 4th edition (DSM-IV; American Psychiatric Association, 1994) specifies a developmental relationship between oppositional defiant disorder (ODD) and conduct disorder (CD). Evidence for this link is ... Full text Link to item Cite

Psychiatric symptoms in bereaved versus nonbereaved youth and young adults: a longitudinal epidemiological study.

Journal Article J Am Acad Child Adolesc Psychiatry · November 2010 OBJECTIVE: To examine potential differences in psychiatric symptoms between parent-bereaved youth (N = 172), youth who experienced the death of another relative (N = 815), and nonbereaved youth (N = 235), aged 11 to 21 years, above and beyond antecedent en ... Full text Link to item Cite

Outcomes of early pubertal timing in young women: a prospective population-based study.

Journal Article Am J Psychiatry · October 2010 OBJECTIVE: Early pubertal timing in girls is associated with psychosocial problems throughout adolescence, but it is unclear whether these problems persist into young adulthood. The authors analyzed outcomes in adolescence and young adulthood in girls in a ... Full text Link to item Cite

Posttraumatic stress without trauma in children.

Journal Article Am J Psychiatry · September 2010 OBJECTIVE: It remains unclear to what degree children show signs of posttraumatic stress disorder (PTSD) after experiencing low-magnitude stressors, or stressors milder than those required for the DSM-IV extreme stressor criterion. METHOD: A representative ... Full text Link to item Cite

In reply

Journal Article JAMA · September 1, 2010 Full text Cite

Longitudinal dimensionality of adolescent psychopathology: testing the differentiation hypothesis.

Journal Article J Child Psychol Psychiatry · August 2010 BACKGROUND: The differentiation hypothesis posits that the underlying liability distribution for psychopathology is of low dimensionality in young children, inflating diagnostic comorbidity rates, but increases in dimensionality with age as latent syndrome ... Full text Link to item Cite

Association of family income supplements in adolescence with development of psychiatric and substance use disorders in adulthood among an American Indian population.

Journal Article JAMA · May 19, 2010 CONTEXT: In a natural experiment in which some families received income supplements, prevalence of adolescent behavioral symptoms decreased significantly. These adolescents are now young adults. OBJECTIVE: To examine the effects of income supplements in ad ... Full text Link to item Cite

Predictors of nonmedical ADHD medication use by college students.

Journal Article J Atten Disord · May 2010 OBJECTIVE: To identify the predictors of nonmedical ADHD medication use by college students. PARTICIPANTS: A total of 843 undergraduates attending one public or one private university in southeastern United States. METHOD: Students completed a Web-based su ... Full text Link to item Cite

Specifying criminogenic strains: Stress dynamics and conduct disorder trajectories

Journal Article Deviant Behavior · January 1, 2010 This article examines family stress dynamics and conduct disorder trajectories prospectively in the lives of adolescents from the Great Smoky Mountains Study of Youth (n = 1,319). Semi-parametric mixture models are used to identify distinct trajectories of ... Full text Cite

Parents' Incomes and Children's Outcomes: A Quasi-Experiment.

Journal Article Am Econ J Appl Econ · January 2010 We examine the role that an exogenous increase in household income due to a government transfer unrelated to household characteristics plays in children's long run outcomes. Children in affected households have higher levels of education in their young adu ... Full text Open Access Link to item Cite

Motives and perceived consequences of nonmedical ADHD medication use by college students: are students treating themselves for attention problems?

Journal Article J Atten Disord · November 2009 OBJECTIVE: This study examines why college students without a prescription take ADHD medication, what they perceive the consequences of this to be, and whether attention problems are associated with this behavior. METHOD: More than 3,400 undergraduates att ... Full text Link to item Cite

Self-reported ADHD and adjustment in college: cross-sectional and longitudinal findings.

Journal Article J Atten Disord · November 2009 OBJECTIVE: To examine the association between self-reported ADHD and college adjustment. PARTICIPANTS: Study 1 included nearly 3400 undergraduates attending a public and private university. Study 2 included 846 students who participated during freshman and ... Full text Link to item Cite

Measurement and design for life course studies of individual differences and development

Journal Article · September 1, 2009 This chapter reviews methods for studying individual differences across the life course. It starts from the position that even when a life course study is basically observational or descriptive, there is an underlying concern to understand more about causa ... Full text Cite

The misuse and diversion of prescribed ADHD medications by college students.

Journal Article J Atten Disord · September 2009 OBJECTIVE: This study assesses the misuse and diversion of prescribed attention-deficit/hyperactivity disorder (ADHD) medications. METHOD: One hundred fifteen students, attending two universities, with prescriptions for ADHD medications completed a Web sur ... Full text Link to item Cite

Childhood and adolescent psychiatric disorders as predictors of young adult disorders.

Journal Article Arch Gen Psychiatry · July 2009 CONTEXT: Most adults with a psychiatric disorder first met diagnostic criteria during childhood and/or adolescence, yet specific homotypic and heterotypic patterns of prediction have not been firmly established. OBJECTIVE: To establish which childhood and ... Full text Link to item Cite

Lifecourse Priorities Among Appalachian Emerging Adults: Revisiting Wallace's Organization of Diversity.

Journal Article Ethos · June 2009 We examine how social demographics (gender, age, or race-ethnicity), census tract characteristics, and family environment during childhood relate to variability in the lifecourse priorities of 344 Cherokee and white youth during emerging adulthood (age 19- ... Full text Link to item Cite

Design and field procedures in the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A).

Journal Article Int J Methods Psychiatr Res · June 2009 An overview is presented of the design and field procedures of the US National Comorbidity Survey Replication Adolescent Supplement (NCS-A), a US face-to-face household survey of the prevalence and correlates of DSM-IV mental disorders. The survey was base ... Full text Link to item Cite

Configurations of common childhood psychosocial risk factors.

Journal Article J Child Psychol Psychiatry · April 2009 BACKGROUND: Co-occurrence of psychosocial risk factors is commonplace, but little is known about psychiatrically-predictive configurations of psychosocial risk factors. METHODS: Latent class analysis (LCA) was applied to 17 putative psychosocial risk facto ... Full text Link to item Cite

National comorbidity survey replication adolescent supplement (NCS-A): I. Background and measures.

Journal Article J Am Acad Child Adolesc Psychiatry · April 2009 OBJECTIVE: This article presents an overview of the background and measures used in the National Comorbidity Survey Replication Adolescent Supplement (NCS-A). METHOD: The NCS-A is a national psychiatric epidemiological survey of adolescents aged 13 to 17 y ... Full text Link to item Cite

National comorbidity survey replication adolescent supplement (NCS-A): II. Overview and design.

Journal Article J Am Acad Child Adolesc Psychiatry · April 2009 OBJECTIVE: To present an overview of the design and field procedures of the National Comorbidity Survey Replication Adolescent Supplement (NCS-A). METHOD: The NCS-A is a nationally representative face-to-face household survey of the prevalence and correlat ... Full text Link to item Cite

Editorial: How epidemiology helps.

Journal Article J Child Psychol Psychiatry · April 2009 Full text Link to item Cite

Response

Journal Article Science · March 18, 2009 Full text Cite

Moving from ethnography to epidemiology: lessons learned in Appalachia.

Journal Article Ann Hum Biol · 2009 BACKGROUND: Anthropologists are beginning to translate insights from ethnography into tools for population studies that assess the role of culture in human behavior, biology, and health. AIM: We describe several lessons learned in the creation and administ ... Full text Link to item Cite

Nosology and measurement in child and adolescent psychiatry.

Journal Article J Child Psychol Psychiatry · January 2009 The last 50 years have witnessed enormous strides in the measurement and classification of child and adolescent psychiatric disorders. Debates about whether we should continue to depend upon a categorical nosology still continue, but we argue that, despite ... Full text Link to item Cite

Tracking biocultural pathways in population health: the value of biomarkers.

Journal Article Ann Hum Biol · 2009 BACKGROUND: Cultural factors and biomarkers are emerging emphases in social epidemiology that readily ally with human biology and anthropology. Persistent health challenges and disparities have established biocultural roots, and environment plays an integr ... Full text Link to item Cite

Research ethics. Certificates of confidentiality and compelled disclosure of data.

Journal Article Science · November 14, 2008 Certificates of Confidentiality have gained prominence in the context of efforts to build large-scale research platforms and new requirements for an unprecedented degree of data sharing. There is, however, a remarkable paucity of evidence upon which to bas ... Full text Link to item Cite

Cultural and community determinants of subjective social status among Cherokee and White youth.

Journal Article Ethn Health · September 2008 BACKGROUND: . Subjective social status (SSS) is associated with physical and mental health in diverse samples. However, community, cultural, and ethnic influences on SSS are poorly understood, especially among rural and American Indian populations. OBJECTI ... Full text Link to item Cite

Editorial: Letter from America

Journal Article Journal of Child Psychology and Psychiatry and Allied Disciplines · July 1, 2008 Full text Cite

Adjustment to college in students with ADHD.

Journal Article J Atten Disord · May 2008 OBJECTIVE: To examine college adjustment in students reporting an ADHD diagnosis and the effect of medication treatment on students' adjustment. METHOD: 1,648 first-semester freshmen attending a public and a private university completed a Web-based survey ... Full text Link to item Cite

Specificity of putative psychosocial risk factors for psychiatric disorders in children and adolescents.

Journal Article J Child Psychol Psychiatry · January 2008 BACKGROUND: Most psychosocial risk factors appear to have general rather than specific patterns of association with common childhood and adolescence disorders. However, previous research has typically failed to 1) control for comorbidity among disorders, 2 ... Full text Link to item Cite

What do childhood anxiety disorders predict?

Journal Article J Child Psychol Psychiatry · December 2007 BACKGROUND: Few longitudinal studies of child and adolescent psychopathology have examined the links between specific childhood anxiety disorders and adolescent psychiatric disorder. In this paper we test the predictive specificity of separation anxiety di ... Full text Link to item Cite

Childhood psychiatric disorders and young adult crime: a prospective, population-based study.

Journal Article Am J Psychiatry · November 2007 OBJECTIVE: While psychopathology is common in criminal populations, knowing more about what kinds of psychiatric disorders precede criminal behavior could be helpful in delineating at-risk children. The authors determined rates of juvenile psychiatric diso ... Full text Link to item Cite

Traumatic events and posttraumatic stress in childhood.

Journal Article Arch Gen Psychiatry · May 2007 CONTEXT: Traumatic events are common and are related to psychiatric impairment in childhood. Little is known about the risk for posttraumatic stress disorder (PTSD) across different types of trauma exposure in children. OBJECTIVE: To examine the developmen ... Full text Link to item Cite

Pubertal maturation and the development of alcohol use and abuse.

Journal Article Drug Alcohol Depend · April 2007 OBJECTIVE: To examine the impact of various aspects of puberty on risk of using alcohol and developing alcohol use disorder (AUD). METHODS: Data come from the Great Smoky Mountains Study, a longitudinal study of a representative sample of 1420 youth aged 9 ... Full text Link to item Cite

Prediction from low birth weight to female adolescent depression: a test of competing hypotheses.

Journal Article Arch Gen Psychiatry · March 2007 CONTEXT: Low birth weight (LBW) predicts later-onset hypertension and diabetes mellitus. Its role as a predictor of depression is unclear. OBJECTIVES: To examine whether LBW predicts depression in male and female children and adolescents and to compare the ... Full text Link to item Cite

Differences among children whose mothers have been in contact with the criminal justice system

Journal Article Women and Criminal Justice · 2007 In order to effectively help children whose mothers become involved with the criminal justice system, it is important to understand their differing needs. To that end, the analyses described in this article explore the heterogeneity in parent and family ri ... Full text Cite

Service costs of caring for adolescents with mental illness in a rural community, 1993-2000.

Journal Article Am J Psychiatry · January 2007 OBJECTIVE: Costs of treating child psychiatric disorders fall on educational, primary care, juvenile justice, and social service agencies as well as on psychiatric services. The authors estimated multiagency mental health costs by integrating service unit ... Full text Link to item Cite

Environmental vulnerabilities and posttraumatic stress disorder (PTSD) among children with different personality styles

Journal Article · December 1, 2006 Children who survive traumatic events are at increased risk for serious emotional disturbance, including posttraumatic stress disorder (PTSD). Many factors influence children's emotional reactions to traumatic experiences, including the severity and durati ... Cite

Is there an epidemic of child or adolescent depression?

Journal Article J Child Psychol Psychiatry · December 2006 BACKGROUND: Both the professional and the general media have recently published concerns about an 'epidemic' of child and adolescent depression. Reasons for this concern include (1) increases in antidepressant prescriptions, (2) retrospective recall by suc ... Full text Link to item Cite

Bayesian semi-parametric ROC analysis.

Journal Article Stat Med · November 30, 2006 This paper describes a semi-parametric Bayesian approach for estimating receiver operating characteristic (ROC) curves based on mixtures of Dirichlet process priors (MDP). We address difficulties in modelling the underlying distribution of screening scores ... Full text Link to item Cite

Prevalence, clinical correlates, and longitudinal course of severe mood dysregulation in children.

Journal Article Biol Psychiatry · November 1, 2006 BACKGROUND: Controversy concerning the diagnosis of pediatric bipolar disorder (BD) has focused attention on children with chronic irritability and hyperarousal. This syndrome has been called the "broad BD phenotype" or severe mood dysregulation (SMD). Thi ... Full text Link to item Cite

Puberty and depression.

Journal Article Child Adolesc Psychiatr Clin N Am · October 2006 Unipolar depression only becomes more common in girls than boys after the age of 13, as a result of an increased incidence of depressive episodes in girls at that time. This article reviews evidence that links multiple dimensions of maturation in the hypot ... Full text Link to item Cite

Proximal psychiatric risk factors for suicidality in youth: the Great Smoky Mountains Study.

Journal Article Arch Gen Psychiatry · September 2006 CONTEXT: Psychiatric disorder is a major risk factor for suicidality but has poor positive predictive value. OBJECTIVES: To characterize proximal risks for suicidality associated with anxiety, depressive, disruptive behavior, and substance use disorders, a ... Full text Link to item Cite

About papers that are not accepted for publication.

Journal Article J Child Psychol Psychiatry · September 2006 Full text Link to item Cite

10-year research update review: the epidemiology of child and adolescent psychiatric disorders: II. Developmental epidemiology.

Journal Article J Am Acad Child Adolesc Psychiatry · January 2006 OBJECTIVE: To describe the growth of developmental epidemiology in the past decade and to illustrate it with examples of recent studies. METHOD: A review of publications on developmental epidemiology in the past 10 years and a discussion of some key exampl ... Full text Link to item Cite

The Life Trajectory Interview for Youth (LTI-Y): method development and psychometric properties of an instrument to assess life-course models and achievement.

Journal Article Int J Methods Psychiatr Res · 2006 This paper describes the rationale, development and psychometric properties of the Life Trajectory Interview for Youth (LTI-Y), an instrument designed to assess cognitive models of the life course and life-course achievement. This method was developed over ... Full text Link to item Cite

Editorial

Journal Article Journal of Child Psychology and Psychiatry and Allied Disciplines · January 1, 2006 Full text Cite

Defining oppositional defiant disorder.

Journal Article J Child Psychol Psychiatry · December 2005 BACKGROUND: ICD-10 and DSM-IV include similar criterial symptom lists for conduct disorder (CD) and oppositional defiant disorder (ODD), but while DSM-IV treats each list separately, ICD-10 considers them jointly. One consequence is that ICD-10 identifies ... Full text Link to item Cite

The developmental epidemiology of anxiety disorders: phenomenology, prevalence, and comorbidity.

Journal Article Child Adolesc Psychiatr Clin N Am · October 2005 This article argues that the quality of diagnostic tools used to measure anxiety disorders in children and adolescents has improved enormously in the past few years. As a result, prevalence estimates are less erratic, understanding of comorbidity is increa ... Full text Link to item Cite

10-year research update review: the epidemiology of child and adolescent psychiatric disorders: I. Methods and public health burden.

Journal Article J Am Acad Child Adolesc Psychiatry · October 2005 OBJECTIVE: To review recent progress in child and adolescent psychiatric epidemiology in the area of prevalence and burden. METHOD: The literature published in the past decade was reviewed under two headings: methods and findings. RESULTS: Methods for asse ... Full text Link to item Cite

Trauma, proximity, and developmental psychopathology: the effects of war and terrorism on children.

Journal Article Neuropsychopharmacology · October 2005 This report summarizes recent literature relevant to the effects of terrorism on children's mental health. The paper addresses three aspects of this topic. In the first section of the paper, data are reviewed concerning the relationships among stress, trau ... Full text Link to item Cite

Editorial

Journal Article Journal of Child Psychology and Psychiatry and Allied Disciplines · April 1, 2005 Full text Cite

Distant Trauma: A prospective study of the effects of september 11th on young adults in North Carolina

Journal Article Applied Developmental Science · October 1, 2004 In 2001, 730 young adults (aged 19–21) were given a detailed assessment as part of an ongoing longitudinal, epidemiological study of the development of psychiatric disorders across childhood and adolescence. Each participant had been interviewed up to 6 ti ... Full text Cite

Genetic and environmental influences on the relative timing of pubertal change.

Journal Article Twin Res · October 2004 A multicategory item-response theory model was developed to characterize developmental changes in three items relating to the assessment of puberty in adolescent twin girls and boys. The model allowed for the fixed effects of age on probability of endorsin ... Full text Link to item Cite

Effects of age at first substance use and psychiatric comorbidity on the development of substance use disorders.

Journal Article Drug Alcohol Depend · September 6, 2004 In this paper, we examine the effects of age at first substance use, and history of psychiatric disorders, on the development of substance use disorder (SUD) by age 16. We use a prospective, longitudinal design to disaggregate the effects of age at first u ... Full text Link to item Cite

Editorial

Journal Article Journal of Child Psychology and Psychiatry and Allied Disciplines · July 1, 2004 Full text Cite

Testosterone, antisocial behavior, and social dominance in boys: pubertal development and biosocial interaction.

Journal Article Biol Psychiatry · March 1, 2004 BACKGROUND: Studies linking testosterone and antisocial behavior in humans have produced mixed results. Adolescence offers a promising period to study this relationship; circulating testosterone increases dramatically in boys during puberty, and antisocial ... Full text Link to item Cite

Relationships between poverty and psychopathology: a natural experiment.

Journal Article JAMA · October 15, 2003 CONTEXT: Social causation (adversity and stress) vs social selection (downward mobility from familial liability to mental illness) are competing theories about the origins of mental illness. OBJECTIVE: To test the role of social selection vs social causati ... Full text Link to item Cite

Relations between Continuous Performance Test performance measures and ADHD behaviors.

Journal Article J Abnorm Child Psychol · October 2003 The Conners' Continuous Performance Test (CPT) is a neuropsychological task that has repeatedly been shown to differentiate ADHD from normal groups. Several variables may be derived from the Conners' CPT including errors of omission and commission, mean hi ... Full text Link to item Cite

Prevalence and development of psychiatric disorders in childhood and adolescence.

Journal Article Arch Gen Psychiatry · August 2003 BACKGROUND: This longitudinal community study assessed the prevalence and development of psychiatric disorders from age 9 through 16 years and examined homotypic and heterotypic continuity. METHODS: A representative population sample of 1420 children aged ... Full text Link to item Cite

School refusal and psychiatric disorders: a community study.

Journal Article J Am Acad Child Adolesc Psychiatry · July 2003 OBJECTIVE: To examine the association between anxious school refusal and truancy and psychiatric disorders in a community sample of children and adolescents using a descriptive rather than etiological definition of school refusal. METHOD: Data from eight a ... Full text Link to item Cite

Obesity and psychiatric disorder: developmental trajectories.

Journal Article Pediatrics · April 2003 OBJECTIVES: To identify age-related trajectories of obesity from childhood into adolescence, and to test the association of these trajectories with the development of psychiatric disorders (conduct disorder, oppositional defiant disorder, attention-deficit ... Full text Link to item Cite

Puberty and depression

Chapter · January 1, 2003 In this chapter we will examine evidence concerning the emergence of an excess of unipolar depression in females during adolescence. We will also present new data from the Great Smoky Mountains Study (GSMS) in support of an approach that combines considera ... Full text Cite

Pathways into and through mental health services for children and adolescents.

Journal Article Psychiatr Serv · January 2003 OBJECTIVE: This study examined points of entry into the mental health service system for children and adolescents as well as patterns of movement through five service sectors: specialty mental health services, education, general medicine, juvenile justice, ... Full text Link to item Cite

Community studies on adolescent substance use, abuse, or dependence and psychiatric comorbidity.

Journal Article J Consult Clin Psychol · December 2002 A literature review on community studies of adolescent substance use, abuse, or dependence (SU/AID) and psychiatric comorbidity yielded 22 articles from 15 studies with information on rates, specificity, timing, and differential patterns of comorbidity by ... Full text Link to item Cite

Depression scale scores in 8-17-year-olds: effects of age and gender.

Journal Article J Child Psychol Psychiatry · November 2002 BACKGROUND: The excess of unipolar depression in females emerges in adolescence. However, studies of age effects on depression scale scores have produced divergent estimates of changes from childhood to adolescence. METHOD: We explored possible reasons for ... Full text Link to item Cite

Psychiatric disorder, impairment, and service use in rural African American and white youth.

Journal Article Arch Gen Psychiatry · October 2002 BACKGROUND: The Caring for Children in the Community Study examined the prevalence of DSM-IV psychiatric disorders and correlates of mental health service use in rural African American and white youth. METHODS: Four thousand five hundred youth aged 9 to 17 ... Full text Link to item Cite

Development and natural history of mood disorders.

Journal Article Biol Psychiatry · September 15, 2002 To expand and accelerate research on mood disorders, the National Institute of Mental Health (NIMH) developed a project to formulate a strategic research plan for mood disorder research. One of the areas selected for review concerns the development and nat ... Full text Link to item Cite

The prevalence of potentially traumatic events in childhood and adolescence.

Journal Article J Trauma Stress · April 2002 This paper examines exposure to potentially traumatic events from middle childhood through adolescence, and vulnerability to such exposure. Analyses are based on the first 4 annual waves of data from a longitudinal general population study of youth in west ... Full text Link to item Cite

The relationship between DSM-IV oppositional defiant disorder and conduct disorder: findings from the Great Smoky Mountains Study.

Journal Article J Child Psychol Psychiatry · March 2002 BACKGROUND: We examine models of the relationship between oppositional defiant disorder (ODD) and conduct disorder (CD) in a community sample. Particular attention is paid to the generalisability of findings based on clinic-referred boys. METHODS: The anal ... Full text Link to item Cite

Epidemiology of psychiatric disability in childhood and adolescence.

Journal Article J Child Psychol Psychiatry · October 2001 The goal of the study was to ascertain the factor structure and prevalence of psychiatric disability in children and adolescents in relation to demographic variables and diagnosis. A representative sample of 1,420 children (9-13 years) from 11 countries in ... Full text Link to item Cite

Poverty, race/ethnicity, and psychiatric disorder: a study of rural children.

Journal Article Am J Public Health · September 2001 OBJECTIVES: This study examined the effect of poverty on the prevalence of psychiatric disorder in rural Black and White children. METHODS: A representative sample of 541 Black children and 379 White children aged 9 to 17 was drawn from 4 predominantly rur ... Full text Link to item Cite

The prospective relation between dimensions of anxiety and the initiation of adolescent alcohol use.

Journal Article J Clin Child Psychol · September 2001 Examined the relation between early anxiety symptomatology (generalized and separation) and initiation of alcohol use 4 years later in an epidemiological sample of 936 children (45% girls), assessed at ages 9, 11, and 13, while controlling for the effects ... Full text Link to item Cite

Reliability of the services assessment for children and adolescents.

Journal Article Psychiatr Serv · August 2001 OBJECTIVE: This study examined the test-retest reliability of a new instrument, the Services Assessment for Children and Adolescents (SACA), for children's use of mental health services. METHODS: A cross-sectional survey was undertaken at two sites. The St ... Full text Link to item Cite

Use of mental health services by youth in contact with social services

Journal Article Social Service Review · January 1, 2001 This article compares mental health service need and use among three groups of children: those with a history of foster care placement, those in contact with departments of social services but never in placement, and those from impoverished families who ha ... Full text Cite

Implications of early versus late onset of attention-deficit/hyperactivity disorder symptoms.

Journal Article J Am Acad Child Adolesc Psychiatry · December 2000 OBJECTIVE: The current diagnostic criteria for attention-deficit/hyperactivity disorder (ADHD) require that symptoms emerge prior to age 7 in order for a formal diagnosis to be considered. However, this age-of-onset criterion (AOC) has recently been questi ... Full text Link to item Cite

Stimulant treatment for children: a community perspective.

Journal Article J Am Acad Child Adolesc Psychiatry · August 2000 OBJECTIVE: To examine the use of prescribed stimulants in relation to research diagnoses of attention-deficit hyperactivity disorder (ADHD) in a community sample of children. METHOD: Data from 4 annual waves of interviews with 9- to 16-year-olds from the G ... Full text Link to item Cite

Effectiveness of nonresidential specialty mental health services for children and adolescents in the "real world".

Journal Article J Am Acad Child Adolesc Psychiatry · February 2000 OBJECTIVE: Although many studies demonstrate the efficacy of a variety of treatments for child and adolescent psychiatric disorders, studies showing the effectiveness of such treatments in ordinary clinical settings have not been forthcoming. This report p ... Full text Link to item Cite

The Child and Adolescent Psychiatric Assessment (CAPA).

Journal Article J Am Acad Child Adolesc Psychiatry · January 2000 OBJECTIVE: To describe the Child and Adolescent Psychiatric Assessment (CAPA). The base interview covers the age range from 9 to 17 years. METHOD: The interview glossary that provides detailed operational definitions of symptoms and severity ratings is des ... Full text Link to item Cite

Developmental psychopathology and public health: past, present, and future.

Journal Article Dev Psychopathol · 2000 Children's healthy mental development has never been the focus of long-term, committed public health policy in the way that early physical health and development have been. We discuss four types of societal response to illness-cure, care, control, and prev ... Full text Link to item Cite

Developmental Trajectories of Aggressive and Non-Aggressive Conduct Problems

Journal Article Journal of Quantitative Criminology · January 1, 2000 Modeling the heterogeneous trajectories along which antisocial behavior develops in childhood and adolescence may contribute in important ways to understanding antecedents of offending in adult life. This paper examines the development of aggressive and no ... Full text Cite

Epstein-Barr virus antibodies in whole blood spots: a minimally invasive method for assessing an aspect of cell-mediated immunity.

Journal Article Psychosom Med · 2000 OBJECTIVE: Study 1: Introduce and validate a method for measuring EBV p18-VCA antibodies in whole blood spots to provide a minimally invasive marker of cell-mediated immune function. Study 2: Apply this method to a large community-based study of psychopath ... Full text Link to item Cite

Bayesian inference for prevalence in longitudinal two-phase studies.

Journal Article Biometrics · December 1999 We consider Bayesian inference and model selection for prevalence estimation using a longitudinal two-phase design in which subjects initially receive a low-cost screening test followed by an expensive diagnostic test conducted on several occasions. The ch ... Full text Link to item Cite

Assessing Functional Impairment and Social Adaptation for Child Mental Health Services Research: A Review of Measures

Journal Article Mental Health Services Research · December 1, 1999 The need for assessing impairment in functioning as an integral part of child mental health services research is discussed. Methodologic difficulties related to problems in case definition, the conceptual definition of impairment and social adaptation, and ... Full text Cite

Development of psychiatric comorbidity with substance abuse in adolescents: effects of timing and sex.

Journal Article J Clin Child Psychol · September 1999 Examined the impact of childhood psychiatric disorders on the prevalence and timing of substance use and abuse and tested for sex differences. A representative population sample of 1,420 children, ages 9, 11, and 13 at intake, were interviewed annually. Am ... Full text Link to item Cite

Pubertal changes in hormone levels and depression in girls.

Journal Article Psychol Med · September 1999 BACKGROUND: Throughout their reproductive years, women suffer from a higher prevalence of depression than men. Before puberty, however, this is not the case. In an earlier study, we found that reaching Tanner Stage III of puberty was associated with increa ... Full text Link to item Cite

Somatic complaints and psychopathology in children and adolescents: stomach aches, musculoskeletal pains, and headaches.

Journal Article J Am Acad Child Adolesc Psychiatry · July 1999 OBJECTIVE: To examine the associations of somatic complaints with DSM-III-R-defined depression, anxiety disorders, conduct disorder, oppositional defiant disorder, and attention-deficit hyperactivity disorder in a population-based sample of children and ad ... Full text Link to item Cite

Use, persistence, and intensity: patterns of care for children's mental health across one year.

Journal Article Community Ment Health J · February 1999 This paper explores the use, persistence, and intensity of services for children's mental health problems across a variety of service sectors during a one year period. Data come from the Great Smoky Mountains Study. Analyses focus on children's psychiatric ... Full text Link to item Cite

Impaired but undiagnosed.

Journal Article J Am Acad Child Adolesc Psychiatry · February 1999 OBJECTIVE: To investigate the prevalence and outcomes of individuals with psychosocial impairment not meeting DSM-III-R criteria for any of 29 well-defined disorders and to suggest operational definitions for not otherwise specified (NOS) diagnoses and V c ... Full text Link to item Cite

Adolescent outcomes of childhood disorders: the consequences of severity and impairment.

Journal Article J Am Acad Child Adolesc Psychiatry · February 1999 OBJECTIVE: To examine the adolescent consequences of clinical and threshold-level psychiatric disorders, with and without significant functional impairment; to predict serious emotional disturbance (SED: clinical-level diagnosis with impairment); and to ex ... Full text Link to item Cite

Comorbidity.

Journal Article J Child Psychol Psychiatry · January 1999 We review recent research on the prevalence, causes, and effects of diagnostic comorbidity among the most common groups of child and adolescent psychiatric disorders; anxiety disorders, depressive disorders, attention deficit hyperactivity disorders, oppos ... Link to item Cite

Commentary on: Prevalence and impact of parent-reported disabling mental health conditions among U.S. children"

Journal Article Journal of the American Academy of Child and Adolescent Psychiatry · January 1, 1999 Full text Cite

Life events and post-traumatic stress: the development of a new measure for children and adolescents.

Journal Article Psychol Med · November 1998 BACKGROUND: A new interview measure of life events and post-traumatic stress disorder (PTSD) has been developed for children and adolescents aged 9 through 17, for use in both epidemiological and clinical studies. It includes 'high magnitude' events associ ... Full text Link to item Cite

Headaches and psychopathology in children and adolescents.

Journal Article J Am Acad Child Adolesc Psychiatry · September 1998 OBJECTIVE: To examine the association between chronic headaches and DSM-III-R-defined psychiatric disorders, including depression, anxiety disorders, conduct disorder, oppositional defiant disorder and attention-deficit hyperactivity disorder, in a populat ... Full text Link to item Cite

Perceived parental burden and service use for child and adolescent psychiatric disorders.

Journal Article Am J Public Health · January 1998 OBJECTIVES: Pediatric chronic physical illness and adult psychiatric disorders are substantial sources of burden for family care-takers, but little attention has been paid to parental burden resulting from children's or adolescents' psychiatric disorders. ... Full text Link to item Cite

Puberty and depression: the roles of age, pubertal status and pubertal timing.

Journal Article Psychol Med · January 1998 BACKGROUND: Previous work has indicated that the 2:1 female:male sex ratio in unipolar depressive disorders does not emerge until some time between ages 10 and 15. METHODS: Data from four annual waves of data collection from the Great Smoky Mountains Study ... Full text Link to item Cite

The prevalence of serious emotional disturbance: A re-analysis of community studies

Journal Article Journal of Child and Family Studies · January 1, 1998 The goal of these analyses was to use existing data to provide an empirically-based estimate of the prevalence in the population of Serious Emotional Disturbance (SED) in children and adolescents, to assist States in their task, required under PL 102-321, ... Full text Cite

Psychiatric disorders among American Indian and white youth in Appalachia: the Great Smoky Mountains Study.

Journal Article Am J Public Health · May 1997 OBJECTIVES: This study examined prevalence of psychiatric disorders, social and family risk factors for disorders, and met and unmet needs for mental health care among Appalachian youth. METHODS: All 9-, 11-, and 13-year-old American Indian children in an ... Full text Link to item Cite

Development of substance use and psychiatric comorbidity in an epidemiologic study of white and American Indian young adolescents the Great Smoky Mountains Study.

Journal Article Drug Alcohol Depend · March 14, 1997 The progression of substance use and the patterns of comorbidity of substance use and psychiatric disorders are explored prospectively in young adolescents enrolled in the Great Smoky Mountains Study. This study is an epidemiologic study of white and Ameri ... Full text Link to item Cite

Insurance coverage and mental health services use by adolescents with serious emotional disturbance

Journal Article Journal of Child and Family Studies · January 1, 1997 This paper examines the relationships between insurance coverage, need, and mental health services in a community-based sample of 1,015youths who were 9, 11, and 13 years old at the beginning of the study. They were followed over a two-year period. A stron ... Full text Cite

Impact of Children's Mental Health Problems on Families: Relationships with Service Use

Journal Article Journal of Emotional and Behavioral Disorders · January 1, 1997 Impact on the family resulting from children's emotional and behavioral problems, with particular attention to relationships between such family impact and use of mental health services, is explored in this article. Data come from the Great Smoky Mountains ... Full text Cite

The relative diagnostic utility of child and parent reports of oppositional defiant behaviors

Journal Article International Journal of Methods in Psychiatric Research · January 1, 1997 It has been suggested that parents are better reporters of oppositional defiant behaviors than are children themselves and that this may be a reason to ignore child reports in the assessment of Oppositional Defiant Disorder (ODD). Using data from the Great ... Full text Cite

The child and adolescent burden assessment (CABA): Measuring the family impact of emotional and behavioral problems

Journal Article International Journal of Methods in Psychiatric Research · January 1, 1997 Background: Though adult psychiatric disorders have been found to be substantial sources of burden for family caretakers, little attention has been paid to the measurement of burden resulting from children's psychiatric disturbance, or to its measurement. ... Full text Cite

The Great Smoky Mountains Study of Youth. Goals, design, methods, and the prevalence of DSM-III-R disorders.

Journal Article Arch Gen Psychiatry · December 1996 BACKGROUND: The Great Smoky Mountains Study of youth focuses on the relationship between the development of psychiatric disorder and the need for and use of mental health services. METHODS: A multistage, overlapping cohorts design was used, in which 4500 o ... Full text Link to item Cite

Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents: factor composition and structure across development

Journal Article International Journal of Methods in Psychiatric Research · December 1, 1996 In the present study, the factor composition of a new, brief, easy-to-administer, depression inventory for children and adolescents, the Short Mood and Feelings Questionnaire (SMFQ), was examined. Using longitudinal data from the Pittsburgh Youth Study, co ... Cite

Development of a short questionnaire for use in epidemiological studies of depression in children and adolescents

Journal Article International Journal of Methods in Psychiatric Research · December 1, 1996 The purpose of the present study was to describe the development and assess the psychometric properties of the Short Mood and Feelings Questionnaire (SMFQ). The SMFQ is a brief, easy-to-administer, self-report measure of childhood and adolescent depression ... Cite

Precision, reliability and accuracy in the dating of symptom onsets in child and adolescent psychopathology.

Journal Article J Child Psychol Psychiatry · September 1996 Dates of onset of psychiatric symptoms are required in determining whether diagnostic criteria are met for a number of disorders and for a variety of research questions. However, little attention has been paid to the precision and reliability of their reca ... Full text Link to item Cite

Toward establishing an empirical basis for the diagnosis of oppositional defiant disorder.

Journal Article J Am Acad Child Adolesc Psychiatry · September 1996 OBJECTIVES: (1) To determine the frequency of occurrence of oppositional defiant behaviors in the general population with a view to establishing empirical frequency cutoffs for the evaluation of oppositional defiant disorder (ODD). (2) To examine the effec ... Full text Link to item Cite

Disappearing Depression in a Population Sample of Boys

Journal Article Journal of Emotional and Behavioral Disorders · January 1, 1996 Although there is evidence that rules of depressive disorders increase during adolescence in girls, the data on the effects of age on depression in boys have been contradictory. In order to shed further light on this issue, the Short Mood and Feelings Ques ... Full text Cite

A test-retest reliability study of child-reported psychiatric symptoms and diagnoses using the Child and Adolescent Psychiatric Assessment (CAPA-C).

Journal Article Psychol Med · July 1995 Seventy-seven 10-18-year-old psychiatric in-patients and out-patients took part in a test-retest study of the Child and Adolescent Psychiatric Assessment (CAPA). They were interviewed on two occasions several days apart. Overall reliability of diagnosis ra ... Full text Link to item Cite

Children's mental health service use across service sectors.

Journal Article Health Aff (Millwood) · 1995 This DataWatch explores the roles of human service sectors (mental health, education, health, child welfare, and juvenile justice) in providing mental health services for children. The data are from the first wave of the Great Smoky Mountains Study of Yout ... Full text Link to item Cite

Developmental epidemiology.

Journal Article Epidemiol Rev · 1995 Full text Link to item Cite

Epidemiology and health care reform.

Journal Article J Am Acad Child Adolesc Psychiatry · September 1994 Full text Link to item Cite

Reliability of self-reported service use: Test-retest consistency of children's responses to the Child and Adolescent Services Assessment (CASA)

Journal Article Journal of Child and Family Studies · September 1, 1994 This paper reports on the reliability of children's responses on the Child and Adolescent Services Assessment (CASA) - a self-report instrument for use with 8- to 18-year-olds that gathers information about services used to address mental health problems. ... Full text Cite

Depressive comorbidity in children and adolescents: empirical, theoretical, and methodological issues.

Journal Article Am J Psychiatry · December 1993 OBJECTIVE: The purpose of the study was to examine comorbidity in the context of child and adolescent depression. METHOD: The authors reviewed recent epidemiological studies using standardized interviews and DSM-III or DSM-III-R criteria. RESULTS: There wa ... Full text Link to item Cite

How can epidemiology improve mental health services for children and adolescents?

Journal Article J Am Acad Child Adolesc Psychiatry · November 1993 Epidemiology, the study of patterns of disease distribution in time and space, can help to improve mental health services for children and adolescents by increasing understanding of the causes, development, and course of psychiatric disorders. For the purp ... Full text Link to item Cite

Toward a developmental epidemiology of the disruptive behavior disorders

Journal Article Development and Psychopathology · January 1, 1993 Epidemiology, the study of patterns of disease distribution in time and space, offers a powerful set of theories and methods for understanding and preventing illness. The disruptive behavior disorders (DBDs) can be studied from the point of view of whether ... Full text Cite

Epidemiology of depression for clinicians.

Journal Article Soc Work · March 1992 This article reviews the epidemiology of depression and the ways this information can be useful for clinicians. The article defines frequently used epidemiological terms, presents prevalence rates and risk factors; discusses the impact and consequences of ... Link to item Cite

Above and below the threshold: Severity of psychiatric symptoms and functional impairment in a pediatric sample

Journal Article Pediatrics · January 1, 1992 Pediatricians are sufficiently concerned about the importance of 'subthreshold' mental health problems to have joined in the movement to create a Diagnostic and Statistical Manual of Mental Disorders for the primary care setting (DSM-PC), with the aim of e ... Cite

Mood variability in adolescents: a study of depressed, nondepressed and comorbid patients.

Journal Article J Affect Disord · December 1991 In a study to examine the variability of mood in psychiatrically disturbed adolescents, 30 inpatients aged 13-17 reported on current depressive symptoms three times a day for seven consecutive days, using a set of visual analog scales (the Adolescent Mood ... Full text Link to item Cite

Married with children: predictors of mental and physical health in middle-aged women.

Journal Article Psychiatry · August 1991 The relationship between current mental and physical health and history of education, marriage, child-rearing and employment was studied in 541 women aged 42-50. Participants, recruited from the community for a longitudinal study of risk factors for cardio ... Full text Link to item Cite

Child mental health and primary pediatric care

Journal Article Current Opinion in Pediatrics · January 1, 1991 Full text Cite

Pervasive and situational hyperactivity--confounding effect of informant: a research note.

Journal Article J Child Psychol Psychiatry · January 1991 Several studies of children with problems of hyperactivity, impulsivity, and inattention (HIA) have suggested that when such behaviour occurs in more than one setting, associated conduct problems, emotional symptoms, and functional impairment are more seri ... Full text Link to item Cite

Who gets treated? Factors associated with referral in children with psychiatric disorders.

Journal Article Acta Psychiatr Scand · June 1990 There is evidence from several industrialized countries that only a small proportion of children with psychiatric disorders receive specialist treatment. It is unclear, however, why some disturbed children are brought for treatment while others are not. To ... Full text Link to item Cite

The pediatrician as gatekeeper to mental health care for children: do parents' concerns open the gate?

Journal Article J Am Acad Child Adolesc Psychiatry · May 1990 Data from a study of children seen for pediatric care in a Health Maintenance Organization are used to examine factors which influence the likelihood that a pediatrician will identify a psychiatric problem and refer an identified child to a mental health s ... Full text Link to item Cite

Anxiety disorders in a pediatric sample

Journal Article Journal of Anxiety Disorders · January 1, 1990 Three hundred children aged 7 to 11, selected from a sequential sample of 789 children enrolled in a health maintenance organization (HMO), were the subjects of this study of the prevalence and correlates of anxiety disorders. Psychiatric interviews with 3 ... Full text Cite

In Reply

Journal Article Archives of General Psychiatry · January 1, 1990 Full text Cite

Anxiety disorders in a pediatric sample

Journal Article Journal of Anxiety Disorders · 1990 Three hundred children aged 7 to 11, selected from a sequential sample of 789 children enrolled in a health maintenance organization (HMO), were the subjects of this study of the prevalence and correlates of anxiety disorders. Psychiatric interviews with 3 ... Cite

Influences of Natural Menopause on Psychological Characteristics and Symptoms of Middle-Aged Healthy Women

Journal Article Journal of Consulting and Clinical Psychology · January 1, 1990 We investigated the psychological and symptom consequences of the natural menopause in a longitudinal study of 541 initially premenopausal healthy women. All women were given an extensive evaluation at baseline. After 3 years of follow-up, 69 women ceased ... Full text Cite

Child psychiatric disorders and their correlates: a primary care pediatric sample.

Journal Article J Am Acad Child Adolesc Psychiatry · November 1989 Psychiatric interviews with 300 parents and children drawn from a first-stage screening sample of 789 children aged 7 to 11 attending primary care pediatric clinics, were carried out using the Diagnostic Interview Schedule for Children. The weighted preval ... Full text Link to item Cite

Developments in child psychiatric epidemiology.

Journal Article J Am Acad Child Adolesc Psychiatry · November 1989 Full text Link to item Cite

More on treated incidence data.

Journal Article J Am Acad Child Adolesc Psychiatry · September 1989 Full text Link to item Cite

The utility of care: Behavioral decision analysis and the development of depression

Journal Article Development and Psychopathology · January 1, 1989 The development of vulnerability to depression is examined from the point of view of one area of cognitive and affective functioning, the processing of information about the future. Drawing on research into how people make choices in an uncertain world, th ... Full text Cite

Psychiatric disorders in pediatric primary care. Prevalence and risk factors.

Journal Article Arch Gen Psychiatry · December 1988 Children aged 7 to 11 years visiting their primary care pediatrician for a wide range of reasons were studied to determine the one-year prevalence of DSM-III disorders and the risk factors associated with them. Parents completing the Child Behavior Checkli ... Full text Link to item Cite

Scales to assess child and adolescent depression: checklists, screens, and nets.

Journal Article J Am Acad Child Adolesc Psychiatry · November 1988 Full text Link to item Cite

Psychopathology in pediatric primary care: The new hidden morbidity

Journal Article Pediatrics · January 1, 1988 In a study of emotional and behavioral problems seen in children attending pediatric primary care clinics in a health maintenance organization, parents of 789 children 7 to 11 years of age completed a behavior screening questionnaire, the Child Behavior Ch ... Cite

Service utilization and psychiatric diagnosis in pediatric primary care: The role of the gatekeeper

Journal Article Pediatrics · January 1, 1988 Levels of morbidity in 789 children 7 to 11 years of age attending two primary care pediatric clinics in a health maintenance organization were examined in relation to psychiatric disturbance. Physical morbidity was measured as mean number of illness episo ... Cite

The new morbidity: who should treat it?

Journal Article J Dev Behav Pediatr · October 1987 Link to item Cite

Validity of the NIMH Diagnostic Interview Schedule for Children: a comparison between psychiatric and pediatric referrals.

Journal Article J Abnorm Child Psychol · December 1985 The NIMH Diagnostic Interview Schedule for Children (DISC) was used to evaluate 40 psychiatric referrals aged 7-11 and 40 pediatric referrals matched for age, sex, race, and socioeconomic status. Each parent and child was interviewed separately using paral ... Full text Link to item Cite

Locus of control and depression in students and psychiatric outpatients.

Journal Article J Clin Psychol · April 1982 Examined the relationship among depression, locus of control of reinforcement, and age in 26 depressed, female, psychiatric outpatients, 26 nondepressed controls, and 55 undergraduate students (23 male, 32 female), of whom 18 were depressed. The mean age o ... Full text Link to item Cite