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John David Norris

Associate Research Professor in Pharmacology & Cancer Biology
Pharmacology & Cancer Biology
Duke Box 3813, Durham, NC 27710
Research Drive, LSRC Bldg, C251, Durham, NC 27710

Selected Grants


Manipulating normal estrogen physiology as a therapeutic approach in cancer

ResearchAssociate Research Professor · Awarded by National Institutes of Health · 2023 - 2028

Elucidation of the mechanisms by which cells recognize and respond to different levels of androgens

ResearchAssociate Research Professor · Awarded by National Institutes of Health · 2022 - 2027

HOXB13 as a therapeutic target in prostate cancer

ResearchAssociate Research Professor · Awarded by Prostate Cancer Foundation · 2020 - 2024

Cancer cell intrinsic and extrinsic actions of steroid hormones in breast tumors

ResearchAssociate Research Professor · Awarded by Department of Defense · 2018 - 2023

Role of ER RNA Binding Domain in Breast Cancer

ResearchAssistant Research Professor · Awarded by Ribometrix LLC · 2022 - 2022

Manipulating normal estrogen physiology as a therapeutic approach in cancer

ResearchAssociate Research Professor · Awarded by National Institutes of Health · 2023 - 2028

Elucidation of the mechanisms by which cells recognize and respond to different levels of androgens

ResearchAssociate Research Professor · Awarded by National Institutes of Health · 2022 - 2027

HOXB13 as a therapeutic target in prostate cancer

ResearchAssociate Research Professor · Awarded by Prostate Cancer Foundation · 2020 - 2024

Cancer cell intrinsic and extrinsic actions of steroid hormones in breast tumors

ResearchAssociate Research Professor · Awarded by Department of Defense · 2018 - 2023

Role of ER RNA Binding Domain in Breast Cancer

ResearchAssistant Research Professor · Awarded by Ribometrix LLC · 2022 - 2022

Identification of Novel Targets in Treatment Resistant Prostate Cancer

ResearchAssociate Research Professor · Awarded by Celgene Corporation · 2017 - 2022

Androgen Receptor Cofactor Profiling of Nido AR Ligands

ResearchPrincipal Investigator · Awarded by Nido Biosciences, Inc. · 2021 - 2022

Evaluation of G1 antiestrogens in models of estrogen action

ResearchAssociate Research Professor · Awarded by G1 Therapeutics Inc. · 2018 - 2019

Evaluation of G1T48 in models of estrogen action

ResearchAssociate Research Professor · Awarded by G1 Therapeutics Inc. · 2017 - 2018

Optimization of ERalpa-LBD-based CAR-T switch

ResearchAssociate Research Professor · Awarded by Cell Design Labs, Inc · 2017 - 2018

Evaluation of the SERD XR5-28 in models of estrogen action

ResearchAssociate Research Professor · Awarded by G1 Therapeutics Inc. · 2016 - 2017

Evaluation of the therapeutic potential of combining VT464 and G1T38 in treatment-resistant prostate and breast cancer models

ResearchAssociate Research Professor · Awarded by Innocrin Pharmaceutical, Inc. · 2016 - 2017

Targeting the CDK 4/6 axis in Castration Resistant Prostate Cancer

ResearchAssociate Research Professor · Awarded by G1 Therapeutics Inc. · 2015 - 2016

Evaluation of VT-464 in AR positive and ER positive breast cancer models

ResearchAssociate Research Professor · Awarded by Innocrin Pharmaceutical, Inc. · 2015 - 2016

Determination of the antiandrogenic properties of VT-464, a novel CYP17 lyase inhibitor

ResearchAssociate Research Professor · Awarded by Viamet Pharmaceuticals · 2014 - 2015

Molecular Determinants of Androgen Receptor Pharmacology

ResearchAssociate Research Professor · Awarded by National Institutes of Health · 2003 - 2013

Integrated instrument systems for maintenance and delivery of RNAi libraries

EquipmentCo Investigator · Awarded by National Institutes of Health · 2008 - 2009

External Relationships


  • BMS Corporation
  • Nido

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.