Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Residency, Anesthesiology, Columbia University, College of Physicians and Surgeons 2002 - 2005
  • Internship and Residency, Anesthesiology, University of Toronto, Faculty of Medicine (Canada) 1999 - 2002
  • M.D., Queens University 1999
• Research
• 

  Selected Grants

  • Mallinckrodt Hip IV vs. PO acetaminophen awarded by Mallinckrodt Pharmaceuticals 2016 - 2020
  • Pacira 327 - Brachial Plexus Block with Exparel for Shoulder Repair PostOp Analgesia awarded by Pacira Pharmaceuticals 2016 - 2018
  • A Multicenter, Randomized, Double-Blind, Placebo-Controlled Study Evaluating the Efficacy, Safety, and Pharmacokinetics of Femoral Nerve Block with EXPAREL for Postsurgical Analgesia in Subjects Undergoing Total Knee Arthroplasty awarded by Pacira Pharmaceuticals 2016 - 2017
• 

  External Relationships

  • Pacira Biosciences, Inc.
• Publications & Artistic Works
• 

  Selected Publications

  • Books

    • Jones, Dean, and Jeff Gadsden. Anesthesiology Self-Assessment and Board Review: BASIC Exam. McGraw-Hill Education / Medical, 2017.
    • Gadsden, J. Regional anesthesia in trauma: A case-based approach, 2012. https://doi.org/10.1017/CBO9781139060202.
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    • Gadsden, J. C., and D. R. Jones. Anesthesiology Oral Board Flash Cards. New York: McGraw-Hill Education/Medical, 2011.

  • Academic Articles

    • Nedeljkovic, Srdjan S., Attila Kett, Manuel C. Vallejo, Jean-Louis Horn, Brendan Carvalho, Xiaodong Bao, Naida M. Cole, et al. “Transversus Abdominis Plane Block With Liposomal Bupivacaine for Pain After Cesarean Delivery in a Multicenter, Randomized, Double-Blind, Controlled Trial.” Anesth Analg 131, no. 6 (December 2020): 1830–39. https://doi.org/10.1213/ANE.0000000000005075.
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    • Dooley, Joshua, William Michael Bullock, Amanda H. Kumar, David B. MacLeod, and Jeffrey Gadsden. “Systematic sonographic and evoked motor identification of the nerve to vastus medialis during adductor canal block.” Reg Anesth Pain Med 45, no. 11 (November 2020): 937–38. https://doi.org/10.1136/rapm-2019-101232.
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    • Gadsden, Jeff C., Siddharth Sata, W Michael Bullock, Amanda H. Kumar, Stuart A. Grant, and Joshua R. Dooley. “The relative analgesic value of a femoral nerve block versus adductor canal block following total knee arthroplasty: a randomized, controlled, double-blinded study.” Korean J Anesthesiol 73, no. 5 (October 2020): 417–24. https://doi.org/10.4097/kja.20269.
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    • Nobuhara, Chloe K., W Michael Bullock, Thomas Bunning, Brian Colin, Mary Cooter, Michael J. Devinney, Michael N. Ferrandino, et al. “A protocol to reduce self-reported pain scores and adverse events following lumbar punctures in older adults.” J Neurol 267, no. 7 (July 2020): 2002–6. https://doi.org/10.1007/s00415-020-09797-1.
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    • Cieslak, Jamie R., Andi N. Rice, Jeffrey C. Gadsden, and Charles A. Vacchiano. “Does Ultrasonographic Measurement of Gastric Content Influence Airway Management Decisions?” Aana J 88, no. 2 (April 2020): 107–13.
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    • VanDusen, Keith W., Sarada Eleswarpu, Eugene W. Moretti, Michael J. Devinney, Donna M. Crabtree, Daniel T. Laskowitz, Marty G. Woldorff, et al. “The MARBLE Study Protocol: Modulating ApoE Signaling to Reduce Brain Inflammation, DeLirium, and PostopErative Cognitive Dysfunction.” J Alzheimers Dis 75, no. 4 (2020): 1319–28. https://doi.org/10.3233/JAD-191185.
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    • Berger, Miles, David M. Murdoch, Janet S. Staats, Cliburn Chan, Jake P. Thomas, Grant E. Garrigues, Jeffrey N. Browndyke, et al. “Flow Cytometry Characterization of Cerebrospinal Fluid Monocytes in Patients With Postoperative Cognitive Dysfunction: A Pilot Study.” Anesth Analg 129, no. 5 (November 2019): e150–54. https://doi.org/10.1213/ANE.0000000000004179.
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    • Gadsden, Jeff, and Steven Orebaugh. “Targeted intracluster supraclavicular brachial plexus block: too close for comfort.” Br J Anaesth 122, no. 6 (June 2019): 713–15. https://doi.org/10.1016/j.bja.2019.02.020.
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    • Gaines, Riley R., Andi N. Rice, Jeffrey C. Gadsden, Brett T. Morgan, and Charles A. Vacchiano. “Use of Near-Infrared Spectroscopy to Measure Tissue Oxygen Saturation During Total Knee Arthroplasty With Use of a Tourniquet.” Aana J 87, no. 3 (June 2019): 192–98.
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    • Berger, Miles, Deborah Oyeyemi, Mobolaji O. Olurinde, Heather E. Whitson, Kent J. Weinhold, Marty G. Woldorff, Lewis A. Lipsitz, et al. “The INTUIT Study: Investigating Neuroinflammation Underlying Postoperative Cognitive Dysfunction.” J Am Geriatr Soc 67, no. 4 (April 2019): 794–98. https://doi.org/10.1111/jgs.15770.
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    • Rambhia, Milly, and Jeff Gadsden. “Pressure monitoring: The evidence so far.” Best Pract Res Clin Anaesthesiol 33, no. 1 (March 2019): 47–56. https://doi.org/10.1016/j.bpa.2019.03.001.
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    • Kumar, Lisa, Amanda H. Kumar, Stuart A. Grant, and Jeff Gadsden. “Updates in Enhanced Recovery Pathways for Total Knee Arthroplasty.” Anesthesiol Clin 36, no. 3 (September 2018): 375–86. https://doi.org/10.1016/j.anclin.2018.04.007.
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    • Gadsden, Jeff. “Current devices used for the monitoring of injection pressure during peripheral nerve blocks.” Expert Rev Med Devices 15, no. 8 (August 2018): 571–78. https://doi.org/10.1080/17434440.2018.1507731.
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    • Kumar, Amanda, Alina Hulsey, Hector Martinez-Wilson, James Kim, and Jeff Gadsden. “The Use of Liposomal Bupivacaine in Erector Spinae Plane Block to Minimize Opioid Consumption for Breast Surgery: A Case Report.” A a Pract 10, no. 9 (May 1, 2018): 239–41. https://doi.org/10.1213/XAA.0000000000000674.
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    • Afonso, Anoushka M., Martin I. Newman, Neil Seeley, Jacob Hutchins, Kevin L. Smith, Gabriel Mena, Jesse C. Selber, Michel H. Saint-Cyr, and Jeffrey C. Gadsden. “Multimodal Analgesia in Breast Surgical Procedures: Technical and Pharmacological Considerations for Liposomal Bupivacaine Use.” Plast Reconstr Surg Glob Open 5, no. 9 (September 2017): e1480. https://doi.org/10.1097/GOX.0000000000001480.
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    • Kumar, Amanda, Neda Sadeghi, Chris Wahal, Jeff Gadsden, and Stuart A. Grant. “Quadratus Lumborum Spares Paravertebral Space in Fresh Cadaver Injection.” Anesth Analg 125, no. 2 (August 2017): 708–9. https://doi.org/10.1213/ANE.0000000000002245.
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    • Gadsden, Jeff. “Enhanced Recovery for Orthopedic Surgery.” Int Anesthesiol Clin 55, no. 4 (2017): 116–34. https://doi.org/10.1097/AIA.0000000000000161.
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    • Giattino, Charles M., Jacob E. Gardner, Faris M. Sbahi, Kenneth C. Roberts, Mary Cooter, Eugene Moretti, Jeffrey N. Browndyke, et al. “Intraoperative Frontal Alpha-Band Power Correlates with Preoperative Neurocognitive Function in Older Adults.” Front Syst Neurosci 11 (2017): 24. https://doi.org/10.3389/fnsys.2017.00024.
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    • Joshi, Girish, Kishor Gandhi, Nishant Shah, Jeff Gadsden, and Shelby L. Corman. “Peripheral nerve blocks in the management of postoperative pain: challenges and opportunities.” J Clin Anesth 35 (December 2016): 524–29. https://doi.org/10.1016/j.jclinane.2016.08.041.
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    • Sutton, Evan, W Michael Bullock, Tayyab Khan, Matthew Eng, and Jeff Gadsden. “Hand Sanitizer as an Alternative to Ultrasound Transmission Gel.” Reg Anesth Pain Med 41, no. 5 (September 2016): 655–56. https://doi.org/10.1097/AAP.0000000000000435.
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    • Sutton, Evan, W Michael Bullock, Jeff Gadsden, and Stuart A. Grant. “The "Step-Off" Technique Can Confirm a Successful Peripheral Nerve Block.” Reg Anesth Pain Med 41, no. 3 (May 2016): 417. https://doi.org/10.1097/AAP.0000000000000395.
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    • Gadsden, Jeff, Malikah Latmore, D Matt Levine, and Allegra Robinson. “High Opening Injection Pressure Is Associated With Needle-Nerve and Needle-Fascia Contact During Femoral Nerve Block.” Reg Anesth Pain Med 41, no. 1 (January 2016): 50–55. https://doi.org/10.1097/AAP.0000000000000346.
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    • Gadsden, Jeffrey, and William J. Long. “Time to Analgesia Onset and Pharmacokinetics After Separate and Combined Administration of Liposome Bupivacaine and Bupivacaine HCl: Considerations for Clinicians.” Open Orthop J 10 (2016): 94–104. https://doi.org/10.2174/1874325001610010094.
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    • Gadsden, Jeff. “Injection pressure monitoring: no more excuses.” J Clin Monit Comput 29, no. 6 (December 2015): 671–72. https://doi.org/10.1007/s10877-015-9712-9.
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    • Sutton, Evan M., W Michael Bullock, and Jeff Gadsden. “The Retroclavicular Brachial Plexus Block: Additional Advantages.” Reg Anesth Pain Med 40, no. 6 (November 2015): 733–34. https://doi.org/10.1097/AAP.0000000000000318.
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    • Gadsden, Jeff, Malikah Latmore, and Daniel M. Levine. “Evaluation of the eZono 4000 with eZGuide for ultrasound-guided procedures.” Expert Rev Med Devices 12, no. 3 (May 2015): 251–61. https://doi.org/10.1586/17434440.2015.995095.
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    • Gadsden, Jeff, and Alicia Warlick. “Regional anesthesia for the trauma patient: improving patient outcomes.” Local Reg Anesth 8 (2015): 45–55. https://doi.org/10.2147/LRA.S55322.
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    • Gadsden, Jeffrey, Sabry Ayad, Jeffrey J. Gonzales, Jaideep Mehta, Jan Boublik, and Jacob Hutchins. “Evolution of transversus abdominis plane infiltration techniques for postsurgical analgesia following abdominal surgeries.” Local Reg Anesth 8 (2015): 113–17. https://doi.org/10.2147/LRA.S96253.
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    • Gadsden, Jeff C., Jason J. Choi, Emily Lin, and Allegra Robinson. “Opening injection pressure consistently detects needle-nerve contact during ultrasound-guided interscalene brachial plexus block.” Anesthesiology 120, no. 5 (May 2014): 1246–53. https://doi.org/10.1097/ALN.0000000000000133.
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    • Levine, M., M. Latmore, C. Vandepitte, J. Gadsden, and A. Hadzic. “It is 3 a.m....do you know where your catheter tip is?” Br J Anaesth 112, no. 4 (April 2014): 757–58. https://doi.org/10.1093/bja/aeu069.
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    • DeOrio, James K., and Jeffrey Gadsden. “Total ankle arthroplasty and perioperative pain.” J Surg Orthop Adv 23, no. 4 (2014): 193–97.
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    • Kwofie, M Kwesi, Uma D. Shastri, and Jeff C. Gadsden. “Reply to Drs Egeler, Jayakumar, and Ford.” Reg Anesth Pain Med 39, no. 1 (January 2014): 82. https://doi.org/10.1097/AAP.0000000000000041.
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    • Hadzic, Admir, Jeff Gadsden, Ali Shariat, Daquan Xu, Uma Shastri, Kwesi Kwofie, Catherine Vandepitte, Kishore Gandhi, Colleen Mitgang, and Kim Gratenstein. “Reply to Drs Rowley and Emamdee.” Reg Anesth Pain Med 38, no. 5 (September 2013): 459. https://doi.org/10.1097/AAP.0b013e3182a26a21.
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    • Choi, Jason J., Emily Lin, and Jeff Gadsden. “Regional anesthesia for trauma outside the operating theatre.” Curr Opin Anaesthesiol 26, no. 4 (August 2013): 495–500. https://doi.org/10.1097/ACO.0b013e3283625ce3.
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    • Kwofie, M Kwesi, Uma D. Shastri, Jeff C. Gadsden, Sanjay K. Sinha, Jonathan H. Abrams, Daquan Xu, and Emine A. Salviz. “The effects of ultrasound-guided adductor canal block versus femoral nerve block on quadriceps strength and fall risk: a blinded, randomized trial of volunteers.” Reg Anesth Pain Med 38, no. 4 (July 2013): 321–25. https://doi.org/10.1097/AAP.0b013e318295df80.
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    • Shariat, Ali N., Admir Hadzic, Daquan Xu, Uma Shastri, Kwesi Kwofie, Kishor Gandhi, Colleen Mitgang McCally, et al. “Fascia lliaca block for analgesia after hip arthroplasty: a randomized double-blind, placebo-controlled trial.” Reg Anesth Pain Med 38, no. 3 (May 2013): 201–5. https://doi.org/10.1097/AAP.0b013e31828a3c7c.
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    • Ripley, Amy, Jose Castro, and Jeff Gadsden. “Local anesthetics, neuraxial anesthesia, and the Brugada syndrome.” J Clin Anesth 25, no. 1 (February 2013): 78–79. https://doi.org/10.1016/j.jclinane.2012.06.012.
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    • Gadsden, Jeff, Ali Shariat, Admir Hadzic, Daquan Xu, Vijay Patel, and Thomas Maliakal. “The sequence of administration of 1.5% mepivacaine and 0.5% bupivacaine does not affect latency of block onset or duration of analgesia in ultrasound-guided interscalene block.” Anesth Analg 115, no. 4 (October 2012): 963–67. https://doi.org/10.1213/ANE.0b013e318265ba9a.
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    • Gadsden, Jeff, Kwesi Kwofie, and Uma Shastri. “Continuous intercostal versus paravertebral blockade for multiple fractured ribs.” J Trauma Acute Care Surg 73, no. 1 (July 2012): 293–94. https://doi.org/10.1097/TA.0b013e31825aaeb5.
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    • Vandepitte, Catherine, Jerry Vloka, Jeff Gadsden, and Admir Hadzic. “Evoked motor response of the sartorius muscle and femoral nerve blockade.” Anesth Analg 114, no. 5 (May 2012): 1140. https://doi.org/10.1213/ANE.0b013e31824bed05.
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    • Gandhi, Kishor, Danielle M. Lindenmuth, Admir Hadzic, Daquan Xu, Vijay S. Patel, Thomas J. Maliakal, and Jeff C. Gadsden. “The effect of stimulating versus conventional perineural catheters on postoperative analgesia following ultrasound-guided femoral nerve localization.” J Clin Anesth 23, no. 8 (December 2011): 626–31. https://doi.org/10.1016/j.jclinane.2011.04.006.
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    • Gadsden, Jeff, Admir Hadzic, Kishor Gandhi, Ali Shariat, Daquan Xu, Thomas Maliakal, and Vijay Patel. “The effect of mixing 1.5% mepivacaine and 0.5% bupivacaine on duration of analgesia and latency of block onset in ultrasound-guided interscalene block.” Anesth Analg 112, no. 2 (February 2011): 471–76. https://doi.org/10.1213/ANE.0b013e3182042f7f.
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    • Gadsden, Jeff, Colleen McCally, and Admir Hadzic. “Monitoring during peripheral nerve blockade.” Curr Opin Anaesthesiol 23, no. 5 (October 2010): 656–61. https://doi.org/10.1097/ACO.0b013e32833d4f99.
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    • Hadzic, A., J. Gadsden, and A. N. Shariat. “Local and nerve block techniques for analgesia after shoulder surgery.” Anaesthesia 65, no. 6 (June 2010): 547–48. https://doi.org/10.1111/j.1365-2044.2010.06385.x.
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    • Wasnick, John D., Laura Chang, Cortessa Russell, and Jeff Gadsden. “Do residency applicants know what the ACGME core competencies are? One program's experience.” Acad Med 85, no. 5 (May 2010): 791–93. https://doi.org/10.1097/ACM.0b013e3181d71d7b.
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    • Gadsden, J. “Reply.” Journal of Clinical Anesthesia 22, no. 2 (March 1, 2010): 151–52. https://doi.org/10.1016/j.jclinane.2010.01.001.
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    • Gadsden, Jeff, Kimberly Gratenstein, and Admir Hadzic. “Intraneural injection and peripheral nerve injury.” Int Anesthesiol Clin 48, no. 4 (2010): 107–15. https://doi.org/10.1097/AIA.0b013e3181f89b10.
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    • Patel, Vijay, Admir Hadzic, Jeff Gadsden, and Kishor Gandhi. “An electrocardiograph artifact caused by peripheral nerve stimulation during an interscalene brachial plexus nerve block.” Reg Anesth Pain Med 35, no. 1 (January 2010): 118–19. https://doi.org/10.1097/AAP.0b013e3181c69c61.
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    • Gadsden, Jeff. “Blocks in anesthetized patients.” Reg Anesth Pain Med 34, no. 6 (November 2009): 604. https://doi.org/10.1097/AAP.0b013e3181ada5ff.
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    • Robards, Christopher, Admir Hadzic, Lakshmanasamy Somasundaram, Takashige Iwata, Jeff Gadsden, Daquan Xu, and Xavier Sala-Blanch. “Intraneural injection with low-current stimulation during popliteal sciatic nerve block.” Anesth Analg 109, no. 2 (August 2009): 673–77. https://doi.org/10.1213/ane.0b013e3181aa2d73.
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    • Gadsden, Jeff C., Tony Tsai, Takeshige Iwata, Lakshmanisamy Somasundarum, Christopher Robards, and Admir Hadzic. “Low interscalene block provides reliable anesthesia for surgery at or about the elbow.” J Clin Anesth 21, no. 2 (March 2009): 98–102. https://doi.org/10.1016/j.jclinane.2008.06.031.
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    • Gadsden, J. “Lumbar plexus or lumbar paravertebral blocks?” Anesthesiology 110, no. 5 (January 1, 2009): 1197. https://doi.org/10.1097/ALN.0b013e31819fde67.
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    • Gadsden, Jeff C., Danielle M. Lindenmuth, Admir Hadzic, Daquan Xu, Lakshmanasamy Somasundarum, and Kamil A. Flisinski. “Lumbar plexus block using high-pressure injection leads to contralateral and epidural spread.” Anesthesiology 109, no. 4 (October 2008): 683–88. https://doi.org/10.1097/ALN.0b013e31818631a7.
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    • Gadsden, Jeff, Stuart Hart, and Alan C. Santos. “Post-cesarean delivery analgesia.” Anesth Analg 101, no. 5 Suppl (November 2005): S62–69. https://doi.org/10.1213/01.ane.0000177100.08599.c8.
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    • Oldman, Matthew, Colin J. L. McCartney, Andrea Leung, Regan Rawson, Anahi Perlas, Jeff Gadsden, and Vincent W. S. Chan. “A survey of orthopedic surgeons' attitudes and knowledge regarding regional anesthesia.” Anesth Analg 98, no. 5 (May 2004): 1486–90. https://doi.org/10.1213/01.ane.0000113549.98873.b1.
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    • Wong, David T., and Jeff C. Gadsden. “Acute upper airway angioedema secondary to acquired C1 esterase inhibitor deficiency: a case report.” Can J Anaesth 50, no. 9 (November 2003): 900–903. https://doi.org/10.1007/BF03018736.
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    • Bansal, Vikram, Uma Shastri, Christopher Canlas, and Jeffrey C. Gadsden. “Diaphragm-Sparing Nerve Blocks for Shoulder Surgery: An Alternative Approach.” Reg Anesth Pain Med 42, no. 4 (n.d.): 544–45. https://doi.org/10.1097/AAP.0000000000000606.
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    • Chin, Ki Jinn, John G. McDonnell, Brendan Carvalho, Aidan Sharkey, Amit Pawa, and Jeffrey Gadsden. “Essentials of Our Current Understanding: Abdominal Wall Blocks.” Reg Anesth Pain Med 42, no. 2 (n.d.): 133–83. https://doi.org/10.1097/AAP.0000000000000545.
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    • Kim, James K., Amanda Kumar, Neda Sadeghi, Michael Shaughnessy, Jeff Gadsden, Karen C. Nielsen, M Steve Melton, and Stephen Klein. “Decreasing the Incidence of Tuohy-Borst Clamp Connector Disconnections From Perineural Catheters: A Quality Improvement Study.” Reg Anesth Pain Med 42, no. 6 (n.d.): 797–98. https://doi.org/10.1097/AAP.0000000000000655.
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    • Yalamuri, Suraj, Rebecca Y. Klinger, W Michael Bullock, Donald D. Glower, Brandi A. Bottiger, and Jeffrey C. Gadsden. “Pectoral Fascial (PECS) I and II Blocks as Rescue Analgesia in a Patient Undergoing Minimally Invasive Cardiac Surgery.” Reg Anesth Pain Med 42, no. 6 (n.d.): 764–66. https://doi.org/10.1097/AAP.0000000000000661.
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  • Book Sections

    • Kim, J., and J. Gadsden. “Monitoring and sedation in regional anesthesia.” In Essentials of Regional Anesthesia: Second Edition, 107–20, 2018. https://doi.org/10.1007/978-3-319-74838-2_6.
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    • Kumar, A., and J. Gadsden. “Future trends in regional anesthesia techniques.” In Essentials of Regional Anesthesia: Second Edition, 695–703, 2018. https://doi.org/10.1007/978-3-319-74838-2_39.
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    • Sadeghi, N., and J. Gadsden. “Future trends in equipment.” In Essentials of Regional Anesthesia: Second Edition, 685–94, 2018. https://doi.org/10.1007/978-3-319-74838-2_38.
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    • Gadsden, J. “Anesthesia considerations for musculoskeletal trauma.” In Trauma Anesthesia, Second Edition, 471–81, 2015. https://doi.org/10.1017/CBO9781139814713.033.
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    • Gadsden, J. “Introduction to pain management.” In Essential Emergency Procedural Sedation and Pain Management, 2012.
    • Gadsden, J. “Monitoring for regional anesthesia.” In Essentials of Regional Anesthesia, 21–36, 2012. https://doi.org/10.1007/978-1-4614-1013-3_2.
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  • Conference Papers

    • Berger, M., J. Browndyke, M. Cooter, W. Bullock, B. Colin, J. Gadsden, E. Iboaya, et al. “Postoperative Changes in CSF AD Markers, Cognition, and fMRI activity.” In Journal of the American Geriatrics Society, 66:S5–S5. WILEY, 2018.
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    • Grant, Stuart A., Christopher Wahal, Amanda Kumar, Neda Sadeghi, Joshua Dooley, Christopher Horazeck, and Jeffrey Gadsden. “A Radiographic Cadaveric Comparison of Transmuscular Quadratus Lumborum Block and Lower Thoracic Paravertebral Block.” In Anesthesia and Analgesia, 124:1041–42. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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    • Grant, Stuart A., Thomas J. Van de Ven, Katherine Grichnik, Michelle Scouras, Jeffrey Gadsden, Gavin Martin, and Joseph P. Mathew. “A Dose Finding Study of the Ideal Analgesic Dose of Intravenous Dexamethasone for Total Knee Arthroplasty.” In Anesthesia and Analgesia, 124:1039–40. LIPPINCOTT WILLIAMS & WILKINS, 2017.
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