Jenna Merenstein

Journal Article NeuroImage: Reports · December 1, 2024 As a surgical treatment following amputation or loss of an upper limb, nearly 200 hand transplantations have been completed to date. We report here a magnetic resonance imaging (MRI) investigation of functional and structural brain connectivity for a bilat ... Full text Cite

Age-related differences in resting-state, task-related, and structural brain connectivity: graph theoretical analyses and visual search performance.

Journal Article Brain Struct Funct · September 2024 Previous magnetic resonance imaging (MRI) research suggests that aging is associated with a decrease in the functional interconnections within and between groups of locally organized brain regions (modules). Further, this age-related decrease in the segreg ... Full text Link to item Cite

Depth- and curvature-based quantitative susceptibility mapping analyses of cortical iron in Alzheimer's disease.

Journal Article Cereb Cortex · January 31, 2024 In addition to amyloid beta plaques and neurofibrillary tangles, Alzheimer's disease (AD) has been associated with elevated iron in deep gray matter nuclei using quantitative susceptibility mapping (QSM). However, only a few studies have examined cortical ... Full text Open Access Link to item Cite

Iron content affects age group differences in associative learning-related fMRI activity.

Journal Article NeuroImage · January 2024 Brain regions accumulate different amounts of iron with age, with older adults having higher iron in the basal ganglia (globus pallidus, putamen, caudate) relative to the hippocampus. This has important implications for functional magnetic resonance imagin ... Full text Cite

Quantitative susceptibility mapping of brain iron in healthy aging and cognition.

Journal Article Neuroimage · November 15, 2023 Quantitative susceptibility mapping (QSM) is a magnetic resonance imaging (MRI) technique that can assess the magnetic properties of cerebral iron in vivo. Although brain iron is necessary for basic neurobiological functions, excess iron content disrupts h ... Full text Open Access Link to item Cite

High-resolution multi-shot diffusion imaging of structural networks in healthy neurocognitive aging.

Journal Article Neuroimage · July 15, 2023 Featured Publication Healthy neurocognitive aging has been associated with the microstructural degradation of white matter pathways that connect distributed gray matter regions, assessed by diffusion-weighted imaging (DWI). However, the relatively low spatial resolution of sta ... Full text Open Access Link to item Cite

Age-related differences in frontoparietal activation for target and distractor singletons during visual search.

Journal Article Atten Percept Psychophys · April 2023 Age-related decline in visual search performance has been associated with different patterns of activation in frontoparietal regions using functional magnetic resonance imaging (fMRI), but whether these age-related effects represent specific influences of ... Full text Open Access Link to item Cite

White matter microstructural correlates of associative learning in the oldest-old.

Journal Article Cognitive, affective & behavioral neuroscience · February 2023 The ability to learn associations between events is critical for everyday functioning (e.g., decision making, social interactions) and has been attributed to structural differences in white matter tracts connecting cortical regions to the hippocampus (e.g. ... Full text Cite

Iron content affects age group differences in associative learning-related fMRI activity

Preprint · 2023 Full text Cite

Neuroimaging studies of mental disorders

Chapter · January 1, 2023 Neuroimaging has transformed our understanding of the neurobiological substrates of mental disorders by revealing images of the brain in living individuals. In this article, we first summarize neuroimaging studies that have revealed differences in brain st ... Full text Cite

Anxiety symptoms and puberty interactively predict lower cingulum microstructure in preadolescent Latina girls.

Journal Article Scientific reports · December 2022 Preadolescence is a period of increased vulnerability for anxiety, especially among Latina girls. Reduced microstructure (fractional anisotropy; FA) of white matter tracts between limbic and prefrontal regions may underlie regulatory impairments in anxiety ... Full text Cite

Bridging patterns of neurocognitive aging across the older adult lifespan.

Journal Article Neuroscience and biobehavioral reviews · April 2022 Magnetic resonance imaging (MRI) studies of brain and neurocognitive aging rarely include oldest-old adults (ages 80 +). But predictions of neurocognitive aging theories derived from MRI findings in younger-old adults (ages ~55-80) may not generalize into ... Full text Cite

Age group differences in learning-related activity reflect task stage, not learning stage.

Journal Article Behavioural brain research · January 2022 Healthy aging is accompanied by declines in the ability to learn associations between events, even when their relationship cannot be described. Previous functional magnetic resonance imaging (fMRI) studies have attributed these implicit associative learnin ... Full text Cite

Age affects white matter microstructure and episodic memory across the older adult lifespan.

Journal Article Neurobiology of aging · October 2021 Diffusion imaging studies have observed age-related degradation of white matter that contributes to cognitive deficits separately in younger-old (ages 65-89) and oldest-old (ages 90+) adults. But it remains unclear whether these age effects are magnified i ... Full text Cite

Neural substrates of mnemonic discrimination: A whole-brain fMRI investigation.

Journal Article Brain and behavior · March 2020 IntroductionA fundamental component of episodic memory is the ability to differentiate new and highly similar events from previously encountered events. Numerous functional magnetic resonance imaging (fMRI) studies have identified hippocampal invo ... Full text Cite