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Jiyong Hong

Professor of Chemistry
Chemistry
Box 90346, Durham, NC 27708-0347
3220 French Science Center, 124 Science Drive, Durham, NC 27708

Selected Grants


TRPM8 in eye health and disease

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2020 - 2029

Inhibiting Rev1-mediated DNA translesion synthesis for cancer therapy

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2028

Identifying essential molecular mechanisms for advanced prostate cancer growth by a new chemical compound

ResearchCollaborator · Awarded by Department of Defense · 2024 - 2027

DART.3-Revolutionizing Neuropsychiatric Treatment through Noninvasive, Programmable Cell-Type-Specific Neuropharmacology

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2027

Developing equilibrative nucleoside transporter inhibitors as non-opioid pain therapeutics

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2026

TRPM8 in eye health and disease

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2020 - 2029

Inhibiting Rev1-mediated DNA translesion synthesis for cancer therapy

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2024 - 2028

Identifying essential molecular mechanisms for advanced prostate cancer growth by a new chemical compound

ResearchCollaborator · Awarded by Department of Defense · 2024 - 2027

DART.3-Revolutionizing Neuropsychiatric Treatment through Noninvasive, Programmable Cell-Type-Specific Neuropharmacology

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2027

Developing equilibrative nucleoside transporter inhibitors as non-opioid pain therapeutics

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2024 - 2026

Neuroactive steroids as novel psychiatric treatments: mechanistic studies

ResearchCo Investigator · Awarded by Washington University in St. Louis · 2021 - 2026

Pharmacological Sciences Training Grant

Inst. Training Prgm or CMEPreceptor · Awarded by National Institutes of Health · 2020 - 2025

Interrogating the cholinergic basis of opioid reinforcement with subcellular precision

ResearchCo Investigator · Awarded by National Institutes of Health · 2020 - 2025

Development of MESH1 inhibitors to treat ferroptosis-associated neurodegeneration

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2024

Structural and chemical biology of human equilibrative nucleoside transporters

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2020 - 2024

Testing D5 compounds in a human version of a published ELISA system

ResearchCo Investigator · Awarded by D5 Therapeutics, Inc · 2021 - 2022

Structural Biological Development of Fungal-Specific Calcineurin Inhibitors

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2014 - 2022

Structure guided design of novel adenosine reuptake inhibitors

FellowshipCollaborating Investigator · Awarded by American Heart Association · 2020 - 2021

Structural and Mechanistic Characterization of MraY Catalysis and Inhibition

ResearchCo Investigator · Awarded by National Institutes of Health · 2017 - 2020

Pharmacological Sciences Training Program

Inst. Training Prgm or CMEParticipating Faculty Member · Awarded by National Institutes of Health · 1975 - 2020

GAANN - Department of Chemistry

Inst. Training Prgm or CMEMentor · Awarded by Department of Education · 2015 - 2019

Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer

EquipmentMajor User · Awarded by National Institutes of Health · 2018 - 2019

Study of Subglutinol A as a Potential Immunomodulatory Agent

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2016 - 2018

Human Stringent Response as Novel Therapeutic Approaches for Breast Cancers

ResearchCo Investigator · Awarded by Department of Defense · 2015 - 2018

MRI: Acquisition of a Triple Quadrupole LC/MS System

EquipmentMajor User · Awarded by National Science Foundation · 2015 - 2018

Targeting Rev1-mediated Translesion Synthesis for Cancer Therapy

ResearchCo-Principal Investigator · Awarded by National Institutes of Health · 2015 - 2017

PKC zeta-Specific Inhibitors for Treatment of Methamphetamine Addiction

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2009 - 2011

Purchase of a Q-TOF LC/MS System

EquipmentMajor User · Awarded by National Institutes of Health · 2010 - 2011

External Relationships


  • D5 Therapeutics

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.