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Jiyong Hong
Professor of Chemistry
Chemistry
jiyong.hong@duke.edu
Box 90346, Durham, NC 27708-0347
3220 French Science Center, 124 Science Drive, Durham, NC 27708
Research
More About This Person
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At a Glance
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Credentials
Education
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Academic Experience
Current Appointments & Affiliations
Previous Appointments & Affiliations
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Expertise
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Research
Selected Grants
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Publications
Selected Publications
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Artistic Works / Events
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Teaching
Recent Courses
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Advising & Mentoring
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Recognition
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Professional Activities
Selected Presentations & Appearances
Service to the Profession
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Selected Grants
LpxH Inhibitors as Novel Therapeutics Against Multidrug-resistant Enterobacterales
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2025 - 2030
TRPM8 in eye health and disease
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2020 - 2029
Inhibiting Rev1-mediated DNA translesion synthesis for cancer therapy
Research
Principal Investigator ·
Awarded by National Cancer Institute ·
2024 - 2028
Identifying essential molecular mechanisms for advanced prostate cancer growth by a new chemical compound
Research
Collaborator ·
Awarded by Department of Defense ·
2024 - 2027
DART.3-Revolutionizing Neuropsychiatric Treatment through Noninvasive, Programmable Cell-Type-Specific Neuropharmacology
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2024 - 2027
Unmasking neuromodulatory control of locomotion
Research
Collaborator ·
Awarded by Washington University in St. Louis ·
2024 - 2027
Developing equilibrative nucleoside transporter inhibitors as non-opioid pain therapeutics
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2024 - 2026
Neuroactive steroids as novel psychiatric treatments: mechanistic studies
Research
Co Investigator ·
Awarded by Washington University in St. Louis ·
2021 - 2026
Interrogating the cholinergic basis of opioid reinforcement with subcellular precision
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2020 - 2026
Pharmacological Sciences Training Grant
Inst. Training Prgm or CME
Preceptor ·
Awarded by National Institutes of Health ·
2020 - 2025
Development of MESH1 inhibitors to treat ferroptosis-associated neurodegeneration
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2022 - 2024
Structural and chemical biology of human equilibrative nucleoside transporters
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2020 - 2024
Discovery and validation of broadly effective LpxH inhibitors as novel therapeutics against multi-drug resistant Gram-negative pathogens
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2019 - 2023
Testing D5 compounds in a human version of a published ELISA system
Research
Co Investigator ·
Awarded by D5 Therapeutics, Inc ·
2021 - 2022
Structural Biological Development of Fungal-Specific Calcineurin Inhibitors
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2014 - 2022
Structure guided design of novel adenosine reuptake inhibitors
Fellowship
Collaborating Investigator ·
Awarded by American Heart Association ·
2020 - 2021
Structural and Mechanistic Characterization of MraY Catalysis and Inhibition
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2017 - 2020
Pharmacological Sciences Training Program
Inst. Training Prgm or CME
Participating Faculty Member ·
Awarded by National Institutes of Health ·
1975 - 2020
GAANN - Department of Chemistry
Inst. Training Prgm or CME
Mentor ·
Awarded by Department of Education ·
2015 - 2019
Thermo Lumos Tribrid High-Resolution Accurate-Mass Tandem Mass Spectrometer
Equipment
Major User ·
Awarded by National Institutes of Health ·
2018 - 2019
Discovery and validation of broadly effective LpxH inhibitors as novel therapeutics against multi-drug resistant Gram-negative pathogens
Research
Co Investigator ·
Awarded by National Institutes of Health ·
2018 - 2019
Study of Subglutinol A as a Potential Immunomodulatory Agent
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2016 - 2018
Human Stringent Response as Novel Therapeutic Approaches for Breast Cancers
Research
Co Investigator ·
Awarded by Department of Defense ·
2015 - 2018
MRI: Acquisition of a Triple Quadrupole LC/MS System
Equipment
Major User ·
Awarded by National Science Foundation ·
2015 - 2018
Targeting Rev1-mediated Translesion Synthesis for Cancer Therapy
Research
Co-Principal Investigator ·
Awarded by National Institutes of Health ·
2015 - 2017
PKC zeta-Specific Inhibitors for Treatment of Methamphetamine Addiction
Research
Principal Investigator ·
Awarded by National Institutes of Health ·
2009 - 2011
Purchase of a Q-TOF LC/MS System
Equipment
Major User ·
Awarded by National Institutes of Health ·
2010 - 2011
