James Morizio | Scholars@Duke

James Morizio
Adjunct Associate Professor in the Department of Electrical and Computer Engineering

Over the last two decades Dr. Morizio's research has been focused on CMOS mixed-signal microelectronics and ASICs used in translational closed-loop, bioelectronic therapies for wireless neural interfaces. These interfaces include sub-system architectures for neural recording and modulation and analog circuits for low noise preamplifier, high channel count multiplexer and programmable current sources. Dr. Morizio's current research is focused on biomedical instrumentation intended for neurological, digestive and immune system disorders with the research goal for human clinical translation. He has over 35 years of analog circuit design experience in industry and academics and co-inventor of 8 patents.

Current Research Interests

Mixed-Signal CMOS circuit design, layout and testing

Bioelectronic circuits for wireless neural interfaces: Recording and Stimulation

Sigma Delta ADC and DACs architecture and circuit design

Ultrasound Pre-Amplifier and multiplexing

Liquid Crystal on Silicon (LCOS) Pixel driver and interface

Broadband Phase Lock Loop Design and Modeling

Ultra Wide Band (Ghz) Transceiver Design: VCOs, PLLs, Antenna Drivers, Buffers

Current Appointments & Affiliations

Adjunct Associate Professor in the Department of Electrical and Computer Engineering, Electrical and Computer Engineering, Pratt School of Engineering 2011
Faculty Network Member of The Energy Initiative, Nicholas Institute-Energy Initiative, Initiatives 2012

Contact Information

219 Hudson Hall, Durham, NC 27708
Box 90291, Durham, NC 27708-0291
jmorizio@ee.duke.edu (919) 201-7759
Website link for Dr. Morizio
click link here

Background
Education, Training, & Certifications
- Ph.D., Duke University 1995
- M.S.E.E., University of Colorado - Denver 1984
- B.S., Virginia Polytech Institute and State University 1982
Previous Appointments & Affiliations
- Assistant Research Professor of Electrical and Computer Engineering, Electrical and Computer Engineering, Pratt School of Engineering 2002 - 2011
Academic Positions Outside Duke
- Visiting Lecturer, Xidian University, Xi’an, China RMB 22914. 2020 - 2022
Recognition
Awards & Honors
- 15 year service award at Triangle BioSystems International. Harvard Bioscience Inc.. December 1, 2016
Expertise
Subject Headings
Research
Selected Grants
- Neuro-CROWN:Optimized Ultra-Flexible CMOS Electrode Arrays for 3D, Low-Noise Neural Interfaces awarded by National Institutes of Health 2021 - 2025
- Development of a digital acoustofluidic system for automating liquid handling in biomedical research awarded by National Institutes of Health 2021 - 2025
- Development of the Osseointegrated Neural Interface for prosthetic control into a pre-clinical translational sheep model awarded by University of Wisconsin - Madison 2020 - 2023
- Multi-axis prosthesis control through an osseointegrated neural interface awarded by University of Wisconsin - Madison 2020 - 2022
- Brain-Machine Interfaces for Monitoring and Modeling Sensorimotor Learning in Primates awarded by National Science Foundation 1999 - 2004
External Relationships
- Triangle Electronic Systems
Publications & Artistic Works
Selected Publications
- Academic Articles
  - Zaer, Hamed, Ashlesha Deshmukh, Dariusz Orlowski, Wei Fan, Pierre-Hugues Prouvot, Andreas Nørgaard Glud, Morten Bjørn Jensen, et al. “An Intracortical Implantable Brain-Computer Interface for Telemetric Real-Time Recording and Manipulation of Neuronal Circuits for Closed-Loop Intervention.” Frontiers in Human Neuroscience 15 (January 2021): 618626. https://doi.org/10.3389/fnhum.2021.618626.
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  - Zhong, Zhanwei, Haodong Zhu, Peiran Zhang, James Morizio, Tony Jun Huang, and Krishnendu Chakrabarty. “Hardware Design and Fault-Tolerant Synthesis for Digital Acoustofluidic Biochips.” Ieee Transactions on Biomedical Circuits and Systems 14, no. 5 (October 2020): 1065–78. https://doi.org/10.1109/tbcas.2020.3018136.
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  - Deshmukh, Ashlesha, Logan Brown, Mary F. Barbe, Alan S. Braverman, Ekta Tiwari, Lucas Hobson, Sudha Shunmugam, et al. “Fully implantable neural recording and stimulation interfaces: Peripheral nerve interface applications.” Journal of Neuroscience Methods 333 (March 2020): 108562. https://doi.org/10.1016/j.jneumeth.2019.108562.
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  - Li, Xiaoran, Shunan Zhong, and James Morizio. “16-Channel biphasic current-mode programmable charge balanced neural stimulation.” Biomedical Engineering Online 16, no. 1 (August 14, 2017): 104. https://doi.org/10.1186/s12938-017-0385-0.
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  - Rossi, Mark A., Vinson Go, Tracy Murphy, Quanhai Fu, James Morizio, and Henry H. Yin. “A wirelessly controlled implantable LED system for deep brain optogenetic stimulation.” Frontiers in Integrative Neuroscience 9 (January 2015): 8. https://doi.org/10.3389/fnint.2015.00008.
    Full Text Open Access Copy
  - Fan, David, Dylan Rich, Tahl Holtzman, Patrick Ruther, Jeffrey W. Dalley, Alberto Lopez, Mark A. Rossi, et al. “A wireless multi-channel recording system for freely behaving mice and rats.” Plos One 6, no. 7 (January 2011): e22033. https://doi.org/10.1371/journal.pone.0022033.
    Full Text Open Access Copy
  - Arora, H., N. Klemmer, J. C. Morizio, and P. D. Wolf. “Enhanced phase noise modeling of fractional-N frequency synthesizers.” Ieee Transactions on Circuits and Systems I: Regular Papers 52, no. 2 (January 1, 2005): 379–95. https://doi.org/10.1109/TCSI.2004.841594.
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  - Lee, S., J. C. Morizio, and K. M. Johnson. “Novel frame buffer pixel circuits for liquid-crystal-on-silicon microdisplays.” Ieee Journal of Solid State Circuits 39, no. 1 (January 1, 2004): 132–39. https://doi.org/10.1109/JSSC.2003.820875.
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  - Obeid, Iyad, James C. Morizio, Karen A. Moxon, Miguel A. L. Nicolelis, and Patrick D. Wolf. “Two multichannel integrated circuits for neural recording and signal processing.” Ieee Trans Biomed Eng 50, no. 2 (February 2003): 255–58. https://doi.org/10.1109/TBME.2002.807643.
    Full Text Link to Item
  - Lee, S., J. C. Morizio, and K. M. Johnson. “A LCOS microdisplay driver with frame buffer pixels.” Information Sciences 149, no. 1–3 (January 1, 2003): 3–11. https://doi.org/10.1016/S0020-0255(02)00239-6.
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  - Won, D. S., I. Obeid, J. C. Morizio, M. A. L. Nicolelis, and P. D. Wolf. “A multichannel CMOS analog front end IC for neural recordings.” Annual International Conference of the Ieee Engineering in Medicine and Biology Proceedings 3 (December 1, 2002): 2070–71.
  - Morizio, J. C., M. Hoke, T. Kocak, C. Geddie, C. Hughes, J. Perry, S. Madhavapeddi, et al. “14-bit 2.2-MS/s sigma-delta ADC's.” Ieee Journal of Solid State Circuits 35, no. 7 (July 1, 2000): 968–76. https://doi.org/10.1109/4.848205.
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- Book Sections
  - Moxon, K. A., J. Morizio, J. K. Chapin, M. A. L. Nicolelis, and P. D. Wolf. “Designing a brain- machine interface for neuroprosthetic control.” In Neural Prostheses for Restoration of Sensory and Motor Function, 179–219, 2000.
- Conference Papers
  - Zhong, Z., H. Zhu, P. Zhang, J. Morizio, T. J. Huang, and K. Chakrabarty. “Hardware Design and Experimental Demonstrations for Digital Acoustofluidic Biochips.” In Biocas 2019 Biomedical Circuits and Systems Conference, Proceedings, 2019. https://doi.org/10.1109/BIOCAS.2019.8919148.
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  - Morizio, J., P. Irazoqui, V. Go, and J. Parmentier. “Wireless headstage for neural prosthetics.” In 2nd International Ieee Embs Conference on Neural Engineering, 2005:414–17, 2005. https://doi.org/10.1109/CNE.2005.1419647.
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  - Lee, S., J. C. Morizio, and K. M. Johnson. “Optimization of frame buffer pixels for an LCOS microdisplay.” In Proceedings of the 7th Joint Conference on Information Sciences, 1470–73, 2003.
    Link to Item
  - Morizio, J., D. Won, I. Obeid, C. Bossetti, M. Nicolelis, and P. Wolf. “16-channel neural pre-conditioning device.” In International Ieee/Embs Conference on Neural Engineering, Ner, 2003-January:104–7, 2003. https://doi.org/10.1109/CNE.2003.1196767.
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  - Morizio, J., S. Guhados, J. Castellucci, and O. Von Ramm. “64-Channel ultrasound transducer amplifier.” In 2003 Southwest Symposium on Mixed Signal Design, Ssmsd 2003, 228–32, 2003. https://doi.org/10.1109/SSMSD.2003.1190432.
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  - Lee, S., J. C. Morizio, and K. M. Johnson. “A LCOS Microdisplay Driver with Frame Buffering Pixels.” In Proceedings of the Joint Conference on Information Sciences, 6:1353–56, 2002.
  - Morizio, J., M. Hoke, T. Kocak, C. Geddie, C. Hughes, J. Perry, S. Madhavapeddi, et al. “SNDR sensitivity analysis for cascaded ΣΔ modulators.” In Proceedings Ieee International Symposium on Circuits and Systems, Vol. 3, 2000. https://doi.org/10.1109/ISCAS.2000.856172.
    Full Text
  - Morizio, J., M. Hoke, T. Kocak, C. Geddie, C. Hughes, J. Perry, S. Madhavapeddi, et al. “14-bit, 2.2MS/s sigma delta ADCs.” In European Solid State Circuits Conference, 82–85, 1999.
Teaching & Mentoring
Recent Courses

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Education, Training, & Certifications

Previous Appointments & Affiliations

Academic Positions Outside Duke

Awards & Honors

Subject Headings

Selected Grants

External Relationships

Selected Publications

Academic Articles

Book Sections

Conference Papers

Recent Courses