Skip to main content

Joe Chakkalakal

Associate Professor in Orthopaedic Surgery
Orthopaedic Surgery

Selected Grants


Engineering Heterocellular Human Skeletal Muscle Tissues to Recreate and Study Native Stem Cell Niche Function

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2029

Engineering a Human Skeletal Muscle Tissue Model of LGMD2B

ResearchCo Investigator · Awarded by National Institutes of Health · 2023 - 2028

Training Program in Developmental and Stem Cell Biology

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2001 - 2027

Cell and Molecular Biology Training Program

Inst. Training Prgm or CMEMentor · Awarded by National Institutes of Health · 2021 - 2026

Genetic and Therapeutic Approaches to Alleviate the Pathology of Massive Rotator Cuff Tears

ResearchCo Investigator · Awarded by National Institutes of Health · 2024 - 2026

Chondrocyte DNA Double-Strand Breaks in the Pathogenesis of Osteoarthritis

ResearchPrincipal Investigator · Awarded by University of Rochester · 2022 - 2025

Understanding and engineering the relationship of muscle stem cells with the neuromuscular junction in aging

ResearchPrincipal Investigator · Awarded by University of Michigan · 2023 - 2025

Cellular Basis for Radiation induced acceleration of sarcopenia in juvenile cancer survivors

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2023

Notch Signaling in non-myogenic mesenchymal cells regulates muscle development

FellowshipMentor · Awarded by National Institutes of Health · 2020 - 2023

Fellowships, Gifts, and Supported Research


Cellular Basis for Radiation induced acceleration of sarcopenia in juvenile cancer survivors · August 1, 2017 - July 31, 2022 Awarded by: National Cancer Institute (Rockville, US)
Interrelationships between age-related skeletal muscle stem cell and NMJ decline · September 30, 2015 - May 31, 2020 Awarded by: National Institute on Aging (Bethesda, US)
Cellular Basis for ADT-Induced Acceleration of Sarcopenia · September 1, 2014 - July 31, 2017 Awarded by: Congressionally Directed Medical Research Programs (Fort Detrick, US)
The Establishment of Motor Unit Homogeneity during Development and after Axon Regeneration · October 1, 2006 - September 30, 2009 Awarded by: Canadian Institutes of Health Research (Ottawa, CA)
Transcriptional and post-transcriptional regulation of utrophin expression in fast versus slow skeletal muscles · May 1, 2003 - April 30, 2006 Awarded by: Canadian Institutes of Health Research (Ottawa, CA)