Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Emergency Medicine Resident, Surgery, Duke University School of Medicine 2015 - 2019
  • M.D., Wright State University, Boonshoft School of Medicine 2015
  • B.A., Saint Louis University 2011
• 

  Previous Appointments & Affiliations

  • Medical Instructor in the Department of Emergency Medicine, Emergency Medicine, Clinical Science Departments 2019 - 2023
• Expertise
• 

  Subject Headings

  • Blunt trauma
  • Emergency Medicine
  • Inflammation
  • Inflammation Mediators
• Research
• 

  Selected Grants

  • A Master Protocol Assessing the Safety, Tolerability, and Efficacy of Anti-Spike (S) SARS-COV-2 Monoclonal Antibodies for the Treatment of Ambulatory Patients with COVID-19 awarded by Regeneron Pharmaceuticals, Inc. 2020 - 2026
  • A PHASE 2 STUDY TO ASSESS THE VIROLOGIC EFFICACY OF REGN10933+REGN10987 ACROSS DIFFERENT DOSE REGIMENS IN OUTPATIENTS WITH SARS-CoV-2 INFECTION awarded by Regeneron Pharmaceuticals, Inc. 2020 - 2023
  • Surgical Critical Care Initiative (SC2I): Civilian application of military decision support tools for critically injured patients. awarded by Henry M. Jackson Foundation 2021 - 2023
  • Sc2i awarded by Henry M. Jackson Foundation 2020 - 2021
  • Outcomes Related to COVID-19 Treated with Hydroxychloroquine among In-patients with Symptomatic Disease awarded by Vanderbilt University Medical Center 2020
  • SC2i awarded by Henry M. Jackson Foundation 2014 - 2020
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Peacock, W Frank, Karina M. Soto-Ruiz, Stacey L. House, Chad M. Cannon, Gary Headden, Brian Tiffany, Sergey Motov, et al. “Utility of COVID-19 antigen testing in the emergency department.” J Am Coll Emerg Physicians Open 3, no. 1 (February 2022): e12605. https://doi.org/10.1002/emp2.12605.
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    • Gerardo, Charles J., Elizabeth Silvius, Seth Schobel, John C. Eppensteiner, Lauren M. McGowan, Eric A. Elster, Allan D. Kirk, and Alexander T. Limkakeng. “Association of a Network of Immunologic Response and Clinical Features With the Functional Recovery From Crotalinae Snakebite Envenoming.” Front Immunol 12 (2021): 628113. https://doi.org/10.3389/fimmu.2021.628113.
       Full Text  Open Access Copy  Link to Item
    • Self, Wesley H., Matthew W. Semler, Lindsay M. Leither, Jonathan D. Casey, Derek C. Angus, Roy G. Brower, Steven Y. Chang, et al. “Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.” Jama 324, no. 21 (December 1, 2020): 2165–76. https://doi.org/10.1001/jama.2020.22240.
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    • Casey, Jonathan D., Nicholas J. Johnson, Matthew W. Semler, Sean P. Collins, Neil R. Aggarwal, Roy G. Brower, Steven Y. Chang, et al. “Rationale and Design of ORCHID: A Randomized Placebo-controlled Clinical Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19.” Ann Am Thorac Soc 17, no. 9 (September 2020): 1144–53. https://doi.org/10.1513/AnnalsATS.202005-478SD.
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    • Eppensteiner, John, Jean Kwun, Uwe Scheuermann, Andrew Barbas, Alexander T. Limkakeng, Maggie Kuchibhatla, Eric A. Elster, Allan D. Kirk, and Jaewoo Lee. “Damage- and pathogen-associated molecular patterns play differential roles in late mortality after critical illness.” Jci Insight 4, no. 16 (August 22, 2019). https://doi.org/10.1172/jci.insight.127925.
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    • Eppensteiner, J., S. Galson, and A. Navas. “Tearing chest pain in adult male.” Visual Journal of Emergency Medicine 16 (July 1, 2019). https://doi.org/10.1016/j.visj.2019.100590.
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    • Eppensteiner, John, and Jaewoo Lee. “Damage-associated molecular patterns in critical illness and multi-organ failure.” Journal of Emergency and Critical Care Medicine 2 (October 2018): 80–80. https://doi.org/10.21037/jeccm.2018.10.04.
       Full Text  Open Access Copy
    • Eppensteiner, John, Robert Patrick Davis, Andrew S. Barbas, Jean Kwun, and Jaewoo Lee. “Immunothrombotic Activity of Damage-Associated Molecular Patterns and Extracellular Vesicles in Secondary Organ Failure Induced by Trauma and Sterile Insults.” Front Immunol 9 (2018): 190. https://doi.org/10.3389/fimmu.2018.00190.
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  • Conference Papers

    • Gerardo, C. J., E. Silvius, S. Schobel, J. Eppensteiner, L. McGowan, A. T. Limkakeng, A. D. Kirk, and E. A. Elster. “ASSOCIATION OF A CYTOKINE RESPONSE NETWORK WITH FUNCTIONAL RECOVERY FROM SNAKEBITE ENVENOMING.” In Toxicon, 182:S15–16, 2020.
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    • Waldron, M., J. C. Eppensteiner, and M. Paniagua. “Preemptive exposure to Geriatrics: An Undergraduate Chronic Care Internship.” In Journal of the American Geriatrics Society, 58:95–95, 2010.
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    • Waldron, M., J. Eppensteiner, M. A. Paniagua, and T. Malmstrom. “PREEMPTIVE EXPOSURE TO GERIATRICS: AN UNDERGRADUATE CHRONIC CARE INTERNSHIP.” In Gerontologist, 50:537–537, 2010.
       Link to Item

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