Scholars@Duke
John C Eppensteiner

John C Eppensteiner

Assistant Professor of Emergency Medicine
Emergency Medicine

Selected Publications

Utility of COVID-19 antigen testing in the emergency department.

Journal Article J Am Coll Emerg Physicians Open · February 2022 BACKGROUND: The BinaxNOW coronavirus disease 2019 (COVID-19) Ag Card test (Abbott Diagnostics Scarborough, Inc.) is a lateral flow immunochromatographic point-of-care test for the qualitative detection of severe acute respiratory syndrome coronavirus 2 (SA ... Full text Link to item Cite

Association of a Network of Immunologic Response and Clinical Features With the Functional Recovery From Crotalinae Snakebite Envenoming.

Journal Article Front Immunol · 2021 BACKGROUND: The immunologic pathways activated during snakebite envenoming (SBE) are poorly described, and their association with recovery is unclear. The immunologic response in SBE could inform a prognostic model to predict recovery. The purpose of this ... Full text Open Access Link to item Cite

Effect of Hydroxychloroquine on Clinical Status at 14 Days in Hospitalized Patients With COVID-19: A Randomized Clinical Trial.

Journal Article JAMA · December 1, 2020 IMPORTANCE: Data on the efficacy of hydroxychloroquine for the treatment of coronavirus disease 2019 (COVID-19) are needed. OBJECTIVE: To determine whether hydroxychloroquine is an efficacious treatment for adults hospitalized with COVID-19. DESIGN, SETTIN ... Full text Link to item Cite

Rationale and Design of ORCHID: A Randomized Placebo-controlled Clinical Trial of Hydroxychloroquine for Adults Hospitalized with COVID-19.

Journal Article Ann Am Thorac Soc · September 2020 The ORCHID (Outcomes Related to COVID-19 treated with Hydroxychloroquine among In-patients with symptomatic Disease) trial is a multicenter, blinded, randomized trial of hydroxychloroquine versus placebo for the treatment of adults hospitalized with corona ... Full text Link to item Cite

Damage- and pathogen-associated molecular patterns play differential roles in late mortality after critical illness.

Journal Article JCI Insight · August 22, 2019 Multiple organ failure (MOF) is the leading cause of late mortality and morbidity in patients who are admitted to intensive care units (ICUs). However, there is an epidemiologic discrepancy in the mechanism of underlying immunologic derangement dependent o ... Full text Link to item Cite

Tearing chest pain in adult male

Journal Article Visual Journal of Emergency Medicine · July 1, 2019 Full text Cite

Damage-associated molecular patterns in critical illness and multi-organ failure

Journal Article Journal of Emergency and Critical Care Medicine · October 2018 Full text Open Access Cite

Immunothrombotic Activity of Damage-Associated Molecular Patterns and Extracellular Vesicles in Secondary Organ Failure Induced by Trauma and Sterile Insults.

Journal Article Front Immunol · 2018 Despite significant improvements in injury prevention and emergency response, injury-related death and morbidity continues to increase in the US and worldwide. Patients with trauma, invasive operations, anti-cancer treatment, and organ transplantation prod ... Full text Link to item Cite

Preemptive exposure to Geriatrics: An Undergraduate Chronic Care Internship.

Conference JOURNAL OF THE AMERICAN GERIATRICS SOCIETY · 2010 Cite