John P. Kirkpatrick | Scholars@Duke

John P. Kirkpatrick
Professor of Radiation Oncology

Malignant and benign tumors of the brain, spine and base of skull. Mathematical modelling of tumor metabolism, mass transfer and the response to ionizing radiation. Enhancing clinical outcome in stereotactic radiosurgery, fractionated stereotactic radiotherapy and stereotactic body radiotherapy.

Current Appointments & Affiliations

Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2018
Associate Professor in Neurosurgery, Neurosurgery, Neurosurgery 2014
Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2000

Contact Information

DUMC Box 3085, Durham, NC 27710
Department Of Radiation Oncology, Durham, NC 27710
john.kirkpatrick@duke.edu (919) 668-7342

Background
Education, Training, & Certifications
- M.D., University of Texas Health Science Center San Antonio 1999
- Ph.D., Rice University 1978
Duke Appointment History
- Associate Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2014 - 2018
- Associate Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2009 - 2014
- Assistant Professor in Surgery, Neurosurgery, Neurosurgery 2011 - 2014
- Assistant Professor of Radiation Oncology, Radiation Oncology, Clinical Science Departments 2004 - 2009
Research
Selected Grants
- Developing knowledge models to enable rapid learning in radiation therapy awarded by National Institutes of Health 2016 - 2020
- Validation of Novel Therapeutic Approach for Leptomeningeal Metastases awarded by Minnetronix, Inc 2018 - 2019
- BMX-001 AS A THERAPEUTIC AGENT FOR TREATMENT OF MULTIPLE BRAIN METASTASES awarded by BioMimetix JV LLC 2018 - 2019
- Decision support for dose prescription in radiation treatment planning awarded by University of North Carolina - Charlotte 2013 - 2015
- Robotic SPECT for Biological Imaging Onboard Radiation Therapy Machines awarded by National Institutes of Health 2011 - 2013
- Cross-disciplinary Training in Medical Physics awarded by National Institutes of Health 2007 - 2013
Publications & Artistic Works
Selected Publications
- Book Sections
  - Kirkpatrick, JP, Kim, G, and Sampson, JH. "Radiation therapy for gliomas." In The Duke Glioma Handbook: Pathology, Diagnosis, and Management, 49-75. March 31, 2016. Full Text
- Conference Papers
  - Birer, SR, Olson, AC, Adamson, J, Hood, R, Susen, M, Kim, G, Salama, JK, and Kirkpatrick, JP. "Hippocampal dose from stereotactic radiosurgery for 4 to 10 brain metastases: Risk factors, feasibility of dose reduction via re-optimization, and patient outcomes." December 2017. Full Text
  - Babatunde, O, Kent, C, Mowery, Y, McSherry, F, II, HJE, Wright, A, Clough, R, Sperduto, W, and Kirkpatrick, JP. "LONG-TERM OUTCOMES FOLLOWING SURGERY AND/OR RADIATION THERAPY IN PATIENTS WITH HIGH-GRADE MENINGIOMA." November 2017. Link to Item
  - Johnson, MO, Kirkpatrick, JP, Weant, MP, Dunn-Pirio, A, Desjardins, A, Randazzo, D, Friedman, HS, and Peters, KB. "A RETROSPECTIVE, SINGLE INSTITUTION STUDY OF CENTRAL NEUROCYTOMA (2004-2016): SURVIVAL, TREATMENT, AND SUPPORTIVE CARE." November 2017. Link to Item
  - Sperduto, P, Deegan, B, Li, J, Jethwa, K, Brown, P, Lockney, N, Beal, K, Rana, N, Attia, A, Shanley, R, Lou, E, Zahra, A, Buatti, J, Molitoris, J, Yu, J, Chiang, V, Masucci, G, Roberge, D, Olson, A, Kirkpatrick, J, Braunstein, S, Sneed, P, Shi, D, Shih, H, and Mehta, M. "Prognostic Factors in Patients with Renal Cell Carcinoma and Brain Metastases." October 2017. Full Text
  - Wang, C, Sun, W, Kirkpatrick, JP, Sampson, J, Chang, Z, and Yin, FF. "Assessment of Concurrent Stereotactic Radiosurgery and Bevacizumab Treatment of Recurrent Malignant Gliomas Using Multiparametric MRI Imaging and Radiomics Analysis." October 1, 2017. Link to Item
  - Xie, T, Ge, Y, Kirkpatrick, J, Yoo, S, Yin, F, and Wu, Q. "An Efficient Tool for Structure Label Harmonization." October 2017. Full Text
  - Narloch, J, Luedke, C, Broadwater, G, Priedigkeit, N, Hall, A, Hyslop, T, Sammons, SL, Huggins-Puhalla, SL, Leone, JP, Ramirez, J, Kirkpatrick, JP, Ewend, MG, Fecci, PE, Brufsky, A, Lee, AV, Anders, CK, and Blackwell, KL. "Number of tumor-infiltrating lymphocytes in breast cancer brain metastases compared to matched breast primaries." May 20, 2017. Full Text Link to Item
  - Affronti, ML, Woodring, S, Allen, K, Kirkpatrick, J, Peters, KB, Herndon, JE, McSherry, F, Healy, PN, Desjardins, A, Vredenburgh, JJ, and Friedman, HS. "Phase II study to evaluate the safety and efficacy of intravenous palonosetron (PAL) in primary malignant glioma (MG) patients receiving standard radiotherapy (RT) and concomitant temozolomide (TMZ)." October 2016. Full Text
  - Birer, SR, Olson, AC, Adamson, J, Kim, GJ, Salama, JK, and Kirkpatrick, JP. "Hippocampal Dose From Stereotactic Radiosurgery for 4 to 10 Brain Metastases: Risk Factors and Feasibility of Dose Reduction Via Reoptimization." October 1, 2016. Link to Item
  - Kent, CL, Mowery, YM, Wright, AO, Kim, GJ, Desjardins, A, Peters, KB, Vlahovic, G, Friedman, HS, Cummings, TJ, McLendon, RE, Friedman, AH, Sampson, JH, and Kirkpatrick, JP. "Long-Term Outcomes for Patients With Atypical or Malignant Meningiomas Treated With Radiation Therapy: A Single-Institution Retrospective Analysis." October 1, 2016. Full Text Link to Item
  - Limon, D, Kim, GJ, McSherry, F, Herndon, J, Fecci, PE, Adamson, J, Sampson, JH, Floyd, SR, Wang, Z, Vlahovic, G, Yin, FF, and Kirkpatrick, JP. "Single-Fraction Radiosurgery for 4 or More Brain Metastases." October 1, 2016. Full Text Link to Item
  - Olson, AC, Patel, K, Mowery, YM, Wynne, J, Ready, N, Kirkpatrick, JP, Salama, AK, and Khan, MK. "Anti-PD-1 Therapy and Stereotactic Radiation for Melanoma and Non-Small Cell Lung Cancer Patients with Brain Metastases: A 2-Institution Series." October 1, 2016. Full Text Link to Item
  - Sperduto, PW, Jiang, W, Brown, PD, Braunstein, SE, Sneed, PK, Wattson, DA, Shih, HA, Bangdiwala, A, Shanley, R, Lockney, NA, Beal, K, Lou, E, Amatruda, T, Sperduto, WA, Kirkpatrick, JP, Yeh, N, Gaspar, LE, Molitoris, JK, Masucci, L, Roberge, D, Yu, JB, Chiang, VL, and Mehta, MP. "The Effect of Gene Mutations on Survival in Patients With Melanoma Following the Development of Brain Metastases." October 1, 2016. Full Text Link to Item
  - Sperduto, PW, Jiang, W, Brown, PD, Braunstein, SE, Sneed, PK, Wattson, DA, Shih, HA, Bangdiwala, A, Shanley, R, Lockney, NA, Beal, K, Lou, E, Amatruda, T, Sperduto, WA, Kirkpatrick, JP, Yeh, N, Gaspar, LE, Molitoris, JK, Masucci, L, Roberge, D, Yu, JB, Chiang, VL, and Mehta, MP. "The Effect of Gene Mutations on Survival in Patients With Melanoma Following the Development of Brain Metastases." October 1, 2016. Link to Item
  - Stanhope, C, Chang, Z, Wang, Z, Yin, F-F, Kim, G, Salama, JK, Kirkpatrick, J, and Adamson, J. "Physics considerations for single-isocenter, volumetric modulated arc radiosurgery for treatment of multiple intracranial targets." May 2016. Full Text
  - Boyle, J, Chino, J, Sampson, J, Desjardins, A, and Kirkpatrick, J. "Stereotactic Radiosurgery for Recurrent High Grade Gliomas: Patterns of Failure." November 2015. Full Text
  - Brownstein, J, Randazzo, D, Kim, G, Peters, K, and Kirkpatrick, J. "A Simple Kinetic Model Provides an Early Prediction of Thrombocytopenia in Malignant Glioma Patients Treated With Radiation and Temozolomide." November 2015. Full Text
  - Kim, G, Barkdoll, T, Sampson, J, Wang, Z, Hoang, J, Fecci, P, Yin, F, and Kirkpatrick, J. "Pathologic Evaluation of Radiographically Enlarging Lesions After Stereotactic Radiosurgery for Brain Metastases." November 2015. Full Text
  - Mowery, Y, Kim, G, Wright, A, Desjardins, A, Peters, K, Vlahovic, G, Friedman, H, Sampson, J, and Kirkpatrick, J. "Outcomes for Patients With Intracranial Meningiomas Treated With Radiation therapy and Bevacizumab: A Single-Institution Retrospective Analysis." November 2015. Full Text
  - Olson, AC, Qin, R, Singh, B, Bhavsar, N, Wolf, S, Salama, JK, Kirkpatrick, JP, and Salama, AK. "Radiosurgery for Brain Metastases in Melanoma Patients Receiving Ipilimumab." November 2015. Full Text
  - Sperduto, P, Yang, T, Beal, K, Pan, H, Brown, P, Ho, Y, Yeh, N, Gaspar, L, Braunstein, S, Sneed, P, Boyle, J, Kirkpatrick, J, Mak, K, Shih, H, Engelman, A, Roberge, D, Arvold, N, Yu, J, Hardie, J, and Mehta, M. "The Effect of Gene Mutations on Survival in Patients With Adenocarcinoma of the Lung Following the Development of Brain Metastases." November 2015. Full Text
  - Wang, Z, Kirkpatrick, J, Kim, G, Kelsey, C, and Yin, F. "Rotational Corrections for Stereotactic Radiosurgery (SRS) of Multiple Brain Metastases Treated With Single Isocenter Technique." November 2015. Full Text
  - Liu, J, Wu, QJ, Yin, FF, Kirkpatrick, JP, Cabrera, A, and Ge, Y. "An active optical flow model for dose prediction in spinal SBRT plans." January 1, 2015. Full Text
  - Lee, C-T, Blackley, A, Landon, C, Spasojevic, I, Kirkpatrick, JP, and Dewhirst, MW. "Abstract 3774: Hyperthermia treatment overcomes temozolomide resistance in glioma cells by downregulating MGMT expression and increasing temozolomide uptake." October 1, 2014. Full Text
  - Liu, J, Wu, Q, Yin, F, Kirkpatrick, J, Cabrera, A, and Ge, Y. "Predicting Dose Distributions in Spinal SBRT Plans Using An Active Appearance Model (AAM)." September 2014. Full Text
  - Kirkpatrick, JP, Wang, Z, Sampson, J, Kelsey, C, Allen, K, Duffy, E, Green, S, Cabrera, A, Palta, M, and Yin, F. "Early Results of a Randomized Trial to Identify an Optimal PTV in Stereotactic Radiosurgery of Brain Metastases." October 1, 2013. Full Text Link to Item
  - Cuneo, KC, Vredenburgh, J, Desjardins, A, Peters, K, Sampson, J, Allen, K, Chang, Z, Duffy, E, Peterson, B, and Kirkpatrick, JP. "Impact of Concurrent and Adjuvant Bevacizumab on the Risk of Radiation Necrosis Following Radiosurgery for Recurrent Glioma." November 1, 2012. Full Text Link to Item
  - Lewis, S, Vredenburgh, J, Desjardins, A, Peters, K, Green, S, Hood, R, Yang, Y, Sampson, J, Wang, Z, and Kirkpatrick, JP. "Patterns of Failure as a Function of Clinical Target Volumes in Patients With GBM Treated With Radiation Therapy (RT), Temozolomide, and Bevacizumab." November 1, 2012. Full Text Link to Item
  - Chang, Z, Kirkpatrick, J, Cai, J, Wang, Z, and Yin, F. "WE-A-217A-09: Evaluating Radiation-Induced White Matter Changes in Patients with Recurrent Malignant Gliomas under Treatment of Stereotactic Radiosurgery Using Diffusion Tensor Imaging." June 2012. Full Text
  - Ge, Y, Minta, T, Kirkpatrick, J, Yuan, L, and Wu, Q. "SU-E-T-23: Ontological Representation of Radiation Treatment Guidelines." June 2011. Full Text
  - Cuneo, KC, Vredenburgh, JJ, Sampson, JH, Reardon, DA, Desjardins, A, Peters, KL, and Kirkpatrick, JP. "USE OF BIOCHEMOTHERAPY AND STEREOTACTIC RADIOSURGERY IN THE MANAGEMENT OF RECURRENT MALIGNANT GLIOMA." November 2010. Link to Item
  - Desjardins, A, Reardon, DA, Peters, KB, II, HJE, Kirkpatrick, JP, Friedman, HS, and Vredenburgh, JJ. "SURVIVAL AND TOXICITY UPDATE OF THE PHASE 2 TRIAL OF BEVACIZUMAB (BV) IN COMBINATION WITH TEMOZOLOMIDE (TMZ) AND RADIATION THERAPY (RT) FOLLOWED BY BV, TMZ, AND IRINOTECAN (CPT-11) FOR NEWLY DIAGNOSED GLIOBLASTOMA MULTIFORME (GBM) PATIENTS." November 2010. Link to Item
  - Adamson, J, Kirkpatrick, J, and Yin, F. "SU-GG-T-483: Does Breath-Hold Immobilization Affect Tumor Radioresistance in Breast?." June 2010. Full Text
  - Wang, Z, Kirkpatrick, J, Chang, Z, Cai, J, Zhuang, T, and Yin, F. "SU-GG-T-530: Comparison of Coplanar and Non-Coplanar Intensity Modulated Arc Techniques for Treatment of Intracranial Multi-Focal Stereotactic Radiosurgery." June 2010. Full Text
  - Kirkpatrick, JP, Yoo, S, Light, K, Antoine, P, Walker, R, Clough, R, Robbins, M, Cozart, H, Tabor, J, and Willett, C. "Implementing a Clinically Driven Electronic Medical Record for Radiation Oncology in a Major Medical Center." 2010. Full Text Link to Item
  - Oh, DS, Reardon, DA, Prosnitz, LR, Gockerman, JP, Sampson, J, and Kirkpatrick, JP. "Low-dose Whole Brain Radiotherapy followed by Radiosurgery for Primary CNS Lymphoma Achieving Partial Response to Induction Chemotherapy." 2010. Full Text Link to Item
  - Brooks, A, Yin, F, Kirkpatrick, J, and Wang, Z. "SU-FF-T-673: Application of RapidArc Technique to Cervical Spine Stereotactic Treatment." June 2009. Full Text
  - Chang, Z, Wang, Z, Wu, Q, Kirkpatrick, J, and Yin, F. "SU-EE-A3-02: Imaging Guided Frameless Stereotactic RadioSurgery Using CBCT 6D Image Registration and 6D Couch On Novalis Tx™ System." June 2009. Full Text
  - Wang, Z, Kirkpatrick, J, Chang, Z, O'Daniel, J, Willett, C, and Yin, F. "SU-FF-T-545: Feasibility Study for Treatment of Intracranial Multi-Focal Stereotactic Radiosurgery with Multiple Intensity Modulated Arc Technique." June 2009. Full Text
  - Wang, Z, Kirkpatrick, J, Wu, Q, Chang, Z, Willett, C, and Yin, F. "SU-FF-T-548: Comparison of Cone-Beam CT and Frame-Based Localizations for Stereotactic Radiosurgery with Fixed Head Rings and Removable Frames." June 2009. Full Text
  - Wu, Q, Yoo, S, Kirkpatrick, J, McMahon, R, Thongphiew, D, and Yin, F. "SU-FF-T-567: Volumetric Modulated Arc Therapy for Spine Body Radiotherapy: Comparison with Static Intensity Modulated Treatment." June 2009. Full Text
  - Kirkpatrick, JP, Vredenburgh, JJ, Desjardins, A, Gururangan, S, Peters, KB, Boulton, ST, Friedman, AH, Friedman, HS, and Reardon, DA. "Phase I study of vandetanib, imatinib mesylate, and hydroxyurea for recurrent malignant glioma." May 20, 2009. Link to Item
  - Brizel, DM, Yoo, DS, Ready, N, Kirkpatrick, JP, Dewhirst, MW, Scher, RL, Cleland, E, MacFall, J, Barboriak, D, and Craciunescu, O. "Synchronous Chemoradiation and Multiple Targeted Drugs for Advanced Head and Neck Cancer." 2009. Full Text Link to Item
  - Cuneo, KC, Vredenburgh, JJ, Sampson, JH, Reardon, DA, Desjardins, A, Willett, CG, and Kirkpatrick, JP. "Bevacizumab in Patients Treated with Stereotactic Radiosurgery for Recurrent Malignant Gliomas is Associated with Improved Overall Survival." 2009. Full Text Link to Item
  - Kirkpatrick, JP, Desjardins, A, Reardon, DA, Friedman, AH, Friedman, HS, and Vredenburgh, JJ. "Radiotherapy, Temozolomide and Bevacizumab followed by Irinotecan, Temozolomide and Bevacizumab Appears Well-tolerated and Efficacious in Newly Diagnosed Glioblastoma Multiforme: Results from a Phase II Trial." 2009. Full Text Link to Item
  - Wang, Z, Kirkpatrick, JP, Wu, QJ, Chang, Z, Willett, CG, and Yin, F. "Imaging Guided Stereotactic Radiosurgery and its Accuracy Compared to Frame-based Localization." 2009. Full Text Link to Item
  - Hosfeld, V, Kirkpatrick, J, and Oldham, M. "SU-GG-T-438: Rind Radiosurgery: Investigation of a Novel Radiation Therapy Technique for the Treatment of Intracranial Lesions." June 2008. Full Text
  - Wang, Z, Wu, Q, Chang, Z, Kirkpatrick, J, and Yin, F. "SU-GG-T-454: Localization Accuracy of Cone-Beam CT Guided Radiosurgery as Investigated Utilizing a Geometric Phantom." June 2008. Full Text
  - Boyd, JA, Kim, DW, Meyer, JJ, Wang, Z, Britz, GW, Wu, J, Yin, F, and Kirkpatrick, JP. "High-definition micro-multileaf collimator in radiosurgery treatment planning for arteriovenous malformations." 2008. Full Text Link to Item
  - Kirkpatrick, JP, Desjardins, A, Reardon, DA, and Vredenburgh, JJ. "Radiotherapy, temozolomide, and bevacizumab followed by irinotecan, temozolomide and bevacizumab in newly diagnosed glioblastoma multiforme: Preliminary results front an ongoing phase II trial." 2008. Full Text Link to Item
  - Nelson, JW, Yoo, DS, Sampson, JH, Isaacs, RE, Larrier, NA, Marks, LB, Yin, FF, Wu, QJ, Wang, Z, and Kirkpatrick, JP. "Stereotactic body radiosurgery of the spine: The duke experience." 2008. Full Text Link to Item
  - Wang, Z, Kirkpatrick, JP, Wu, QJ, Chang, Z, Willett, CG, and Yin, F. "Can cone beam CT replace frame-based localization for stereotactic radiosurgery?." 2008. Full Text Link to Item
  - Wu, QJ, Wang, Z, Kirkpatrick, JP, Chang, Z, Zhou, S, Willett, CG, and Yin, F. "Dosimetrical evaluation of SRS/SBRT techniques." 2008. Full Text Link to Item
  - Yoo, DS, Craciunescu, O, Cleland, E, Barboriak, D, Muradyan, N, Dolguikh, M, Kirkpatrick, JP, Carroll, MD, and Brizel, DM. "Dynamic contrast enhanced magnetic resonance imaging (DCE-MRI) to assess changes in tumor physiology caused by molecular targeted agents in locally advanced head and neck cancer (LAHNC)." 2008. Full Text Link to Item
  - Wang, Z, Nelson, J, Yoo, S, Wu, QJ, Kirkpatrick, J, Larrier, N, Meyer, J, Willett, C, and Yin, F. "SU-FF-T-252: Improvement of Localization Accuracy by Using 3D Cone Beam CT for Stereotactic Body Radiation Therapy of Liver, Lung and Spine Lesions." June 2007. Full Text
  - Kelsey, CR, Mukundan, S, Wang, Z, Fabregas, M, Kelley, K, and Kirkpatrick, JP. "Assessing neurotoxicity from radiosurgery: Results from a prospective study using magnetic resonance spectroscopy." 2007. Full Text Link to Item
  - Kirkpatrick, JP, and Wang, Z. "Increasing the number of orthogonal beam pairs does not improve the biologic effect in normal tissue in a phantom model." 2007. Full Text Link to Item
  - Wang, Z, Wu, Q, Kirkpatrick, JP, Willett, CG, and Yin, F. "Localization for MRI-based radiation treatment of intracranial lesions by using three-dimensional MRI and cone-beam CT matching." 2007. Full Text Link to Item
  - Yin, F, Marks, L, Wang, Z, Kirkpatrick, J, Wu, J, Yoo, S, Larrier, N, Meyer, J, and Willett, C. "SU-FF-T-66: A Technique for Cone-Beam CT-Guided Stereotactic Body Radiation Therapy." June 2006. Full Text
  - Kirkpatrick, JP, Irani, FR, Johnston, SE, Stalnecker, AM, Cooney, TM, Georgas, DL, and Oldham, M. "A novel water-clear, low-modulus bolus material." 2006. Full Text Link to Item
  - Rabbani, ZN, Kirkpatrick, JP, Salahuddin, FK, Bentley, RC, Secord, AA, Greenberg, CS, Havrilesky, LJ, Vujaskovic, Z, Jones, E, and Dewhirst, MW. "Tissue transglutaminase expression in early-stage cervical cancer." 2006. Full Text Link to Item
  - Zhou, S, Hahn, C, Shafman, T, Kirkpatrick, J, Tisch, A, Marks, L, Hawk, T, Turkington, T, Wong, T, and Coleman, R. "SU-FF-T-366: Radiation Dose Response Curve of Human Cerebral Cortex Measured with [F-18]-FDG and [O-15]-H2O PET Imaging." June 2005. Full Text
  - Kirkpatrick, JP, Rabbani, Z, Bentley, R, Hardee, M, Karol, S, Meyer, J, Oosterwijk, E, Havrilesky, L, Secord, A, Vujaskovic, Z, Dewhirst, M, and Jones, E. "Elevated CAIX expression is associated with an increased risk of distant failure in early-stage cervical cancer." 2005. Full Text Link to Item
  - KIRKPATRICK, J, CALINGAERT, B, CLOUGH, R, OLESON, J, QUARANTA, B, HAHN, C, MONTANA, G, INGRAM, S, and ANSCHER, M. "Adjuvant and salvage radiotherapy following radical prostatectomy." September 2004. Full Text
  - Hardee, ME, Kirkpatrick, JP, Snyder, S, Shan, S, Vujaskovic, Z, Rabbani, ZN, Dewhirst, MW, and Blackwell, KL. "Erythropoietin (EPO) has no direct effect on tumor growth or angiogenesis in animal models." July 15, 2004. Link to Item
  - Kirkpatrick, JP, Clough, R, Anscher, MS, and Montana, GS. "Patterns of failure in prostate cancer after primary or post-prostatectomy salvage radiotherapy in the PSA era." November 2002. Link to Item
- Journal Articles
  - Kirkpatrick, JP, Laack, NN, Halasz, LM, Minniti, G, and Chan, MD. "Proton Therapy for Brain Metastases: A Question of Value." International Journal of Radiation Oncology, Biology, Physics 101, no. 4 (July 2018): 830-832. Full Text
  - Sperduto, PW, Deegan, BJ, Li, J, Jethwa, KR, Brown, PD, Lockney, N, Beal, K, Rana, NG, Attia, A, Tseng, C-L, Sahgal, A, Shanley, R, Sperduto, WA, Lou, E, Zahra, A, Buatti, JM, Yu, JB, Chiang, V, Molitoris, JK, Masucci, L, Roberge, D, Shi, DD, Shih, HA, Olson, A, Kirkpatrick, JP, Braunstein, S, Sneed, P, and Mehta, MP. "Effect of Targeted Therapies on Prognostic Factors, Patterns of Care, and Survival in Patients With Renal Cell Carcinoma and Brain Metastases." International Journal of Radiation Oncology, Biology, Physics 101, no. 4 (July 2018): 845-853. Full Text
  - Soliman, H, Ruschin, M, Angelov, L, Brown, PD, Chiang, VLS, Kirkpatrick, JP, Lo, SS, Mahajan, A, Oh, KS, Sheehan, JP, Soltys, SG, and Sahgal, A. "Consensus Contouring Guidelines for Postoperative Completely Resected Cavity Stereotactic Radiosurgery for Brain Metastases." International journal of radiation oncology, biology, physics 100, no. 2 (February 2018): 436-442. Full Text
  - Milano, MT, Grimm, J, Soltys, SG, Yorke, E, Moiseenko, V, Tomé, WA, Sahgal, A, Xue, J, Ma, L, Solberg, TD, Kirkpatrick, JP, Constine, LS, Flickinger, JC, Marks, LB, and El Naqa, I. "Single- and Multi-Fraction Stereotactic Radiosurgery Dose Tolerances of the Optic Pathways." International Journal of Radiation Oncology, Biology, Physics (January 31, 2018). Full Text
  - Sperduto, PW, Jiang, W, Brown, PD, Braunstein, S, Sneed, P, Wattson, DA, Shih, HA, Bangdiwala, A, Shanley, R, Lockney, NA, Beal, K, Lou, E, Amatruda, T, Sperduto, WA, Kirkpatrick, JP, Yeh, N, Gaspar, LE, Molitoris, JK, Masucci, L, Roberge, D, Yu, J, Chiang, V, and Mehta, M. "Estimating Survival in Melanoma Patients With Brain Metastases: An Update of the Graded Prognostic Assessment for Melanoma Using Molecular Markers (Melanoma-molGPA)." International Journal of Radiation Oncology, Biology, Physics 99, no. 4 (November 2017): 812-816. Full Text
  - Limon, D, McSherry, F, Herndon, J, Sampson, J, Fecci, P, Adamson, J, Wang, Z, Yin, F-F, Floyd, S, Kirkpatrick, J, and Kim, GJ. "Single fraction stereotactic radiosurgery for multiple brain metastases." Advances in Radiation Oncology 2, no. 4 (October 2017): 555-563. Full Text Open Access Copy
  - Narloch, JL, Farber, SH, Sammons, S, McSherry, F, Herndon, JE, Hoang, JK, Yin, F-F, Sampson, JH, Fecci, PE, Blackwell, KL, Kirkpatrick, JP, and Kim, GJ. "Biopsy of enlarging lesions after stereotactic radiosurgery for brain metastases frequently reveals radiation necrosis." Neuro Oncology 19, no. 10 (October 2017): 1391-1397. Full Text
  - Kirkpatrick, JP, Laack, NN, Shih, HA, and Gondi, V. "Management of GBM: a problem of local recurrence." Journal of neuro-oncology 134, no. 3 (September 2017): 487-493. (Review) Full Text
  - Lee, C-T, Zhou, Y, Roy-Choudhury, K, Siamakpour-Reihani, S, Young, K, Hoang, P, Kirkpatrick, JP, Chi, J-TA, Dewhirst, MW, and Horton, JK. "Subtype-Specific Radiation Response and Therapeutic Effect of FAS Death Receptor Modulation in Human Breast Cancer." Radiation Research 188, no. 2 (August 2017): 169-180. Full Text
  - Sperduto, PW, Jiang, W, Brown, PD, Braunstein, S, Sneed, P, Wattson, DA, Shih, HA, Bangdiwala, A, Shanley, R, Lockney, NA, Beal, K, Lou, E, Amatruda, T, Sperduto, WA, Kirkpatrick, JP, Yeh, N, Gaspar, LE, Molitoris, JK, Masucci, L, Roberge, D, Yu, J, Chiang, V, and Mehta, M. "The Prognostic Value of BRAF, C-KIT, and NRAS Mutations in Melanoma Patients With Brain Metastases." International Journal of Radiation Oncology, Biology, Physics 98, no. 5 (August 2017): 1069-1077. Full Text
  - Wang, C, Yin, F-F, Kirkpatrick, JP, and Chang, Z. "Accelerated Brain DCE-MRI Using Iterative Reconstruction With Total Generalized Variation Penalty for Quantitative Pharmacokinetic Analysis: A Feasibility Study." Technology in Cancer Research & Treatment 16, no. 4 (August 2017): 446-460. Full Text
  - Halasz, LM, Soltys, SG, Breneman, JC, Chan, MD, Laack, NN, Minniti, G, and Kirkpatrick, JP. "Treatment of Gliomas: A Changing Landscape." International Journal of Radiation Oncology, Biology, Physics 98, no. 2 (June 2017): 255-258. Full Text
  - Sperduto, PW, Yang, TJ, Beal, K, Pan, H, Brown, PD, Bangdiwala, A, Shanley, R, Yeh, N, Gaspar, LE, Braunstein, S, Sneed, P, Boyle, J, Kirkpatrick, JP, Mak, KS, Shih, HA, Engelman, A, Roberge, D, Arvold, ND, Alexander, B, Awad, MM, Contessa, J, Chiang, V, Hardie, J, Ma, D, Lou, E, Sperduto, W, and Mehta, MP. "Estimating Survival in Patients With Lung Cancer and Brain Metastases: An Update of the Graded Prognostic Assessment for Lung Cancer Using Molecular Markers (Lung-molGPA)." Jama Oncology 3, no. 6 (June 2017): 827-831. Full Text
  - Kirkpatrick, JP, Soltys, SG, Lo, SS, Beal, K, Shrieve, DC, and Brown, PD. "The radiosurgery fractionation quandary: single fraction or hypofractionation?." Neuro Oncology 19, no. suppl_2 (April 2017): ii38-ii49. Full Text
  - Adamson, JD, Cooney, T, Demehri, F, Stalnecker, A, Georgas, D, Yin, F-F, and Kirkpatrick, J. "Characterization of Water-Clear Polymeric Gels for Use as Radiotherapy Bolus." Technology in Cancer Research & Treatment (January 2017): 1533034617710579-null. Full Text
  - Morrison, J, Hood, R, Yin, F-F, Salama, JK, Kirkpatrick, J, and Adamson, J. "Is a single isocenter sufficient for volumetric modulated arc therapy radiosurgery when multiple itracranial metastases are spatially dispersed?." Medical Dosimetry : Official Journal of the American Association of Medical Dosimetrists 41, no. 4 (December 2016): 285-289. Full Text
  - Birer, SR, Olson, AC, Adamson, J, Kim, GJ, Salama, JK, and Kirkpatrick, JP. "Hippocampal Dose From Stereotactic Radiosurgery for 4 to 10 Brain Metastases: Risk Factors and Feasibility of Dose Reduction Via Reoptimization." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): E608-E609. Full Text
  - Faught, AM, Trager, M, Yin, F-F, Kirkpatrick, J, and Adamson, J. "Re-examining TG-142 recommendations in light of modern techniques for linear accelerator based radiosurgery." Medical Physics 43, no. 10 (October 2016): 5437-null. Full Text
  - Kent, CL, Mowery, YM, Wright, AO, Kim, GJ, Desjardins, A, Peters, KB, Vlahovic, G, Friedman, HS, Cummings, TJ, McLendon, RE, Friedman, AH, Sampson, JH, and Kirkpatrick, JP. "Long-Term Outcomes for Patients With Atypical or Malignant Meningiomas Treated With Radiation Therapy: A Single-Institution Retrospective Analysis." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): E83-E84. Full Text
  - Limon, D, Kim, GJ, McSherry, F, Herndon, J, Fecci, PE, Adamson, J, Sampson, JH, Floyd, SR, Wang, Z, Vlahovic, G, Yin, FF, and Kirkpatrick, JP. "Single-Fraction Radiosurgery for 4 or More Brain Metastases." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): E84-E85. Full Text
  - Olson, AC, Patel, K, Mowery, YM, Wynne, J, Ready, N, Kirkpatrick, JP, Salama, AK, and Khan, MK. "Anti-PD-1 Therapy and Stereotactic Radiation for Melanoma and Non-Small Cell Lung Cancer Patients with Brain Metastases: A 2-Institution Series." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): E97-E98. Full Text
  - Sperduto, PW, Jiang, W, Brown, PD, Braunstein, SE, Sneed, PK, Wattson, DA, Shih, HA, Bangdiwala, A, Shanley, R, Lockney, NA, Beal, K, Lou, E, Amatruda, T, Sperduto, WA, Kirkpatrick, JP, Yeh, N, Gaspar, LE, Molitoris, JK, Masucci, L, Roberge, D, Yu, JB, Chiang, VL, and Mehta, MP. "The Effect of Gene Mutations on Survival in Patients With Melanoma Following the Development of Brain Metastases." International journal of radiation oncology, biology, physics 96, no. 2S (October 2016): S178-. Full Text
  - Sperduto, PW, Yang, TJ, Beal, K, Pan, H, Brown, PD, Bangdiwala, A, Shanley, R, Yeh, N, Gaspar, LE, Braunstein, S, Sneed, P, Boyle, J, Kirkpatrick, JP, Mak, KS, Shih, HA, Engelman, A, Roberge, D, Arvold, ND, Alexander, B, Awad, MM, Contessa, J, Chiang, V, Hardie, J, Ma, D, Lou, E, Sperduto, W, and Mehta, MP. "The Effect of Gene Alterations and Tyrosine Kinase Inhibition on Survival and Cause of Death in Patients With Adenocarcinoma of the Lung and Brain Metastases." International Journal of Radiation Oncology, Biology, Physics 96, no. 2 (October 2016): 406-413. Full Text
  - Cabrera, AR, Kirkpatrick, JP, Fiveash, JB, Shih, HA, Koay, EJ, Lutz, S, Petit, J, Chao, ST, Brown, PD, Vogelbaum, M, Reardon, DA, Chakravarti, A, Wen, PY, and Chang, E. "Radiation therapy for glioblastoma: Executive summary of an American Society for Radiation Oncology Evidence-Based Clinical Practice Guideline." Practical Radiation Oncology 6, no. 4 (July 2016): 217-225. Full Text
  - Farber, SH, Tsvankin, V, Narloch, JL, Kim, GJ, Salama, AKS, Vlahovic, G, Blackwell, KL, Kirkpatrick, JP, and Fecci, PE. "Embracing rejection: Immunologic trends in brain metastasis." Oncoimmunology 5, no. 7 (July 2016): e1172153-null. (Review) Full Text
  - Soltys, SG, Kirkpatrick, JP, Laack, NN, Kavanagh, BD, Breneman, JC, and Shih, HA. "Is Less, More? The Evolving Role of Radiation Therapy for Brain Metastases." International Journal of Radiation Oncology*Biology*Physics 92, no. 5 (August 2015): 963-966. Full Text
  - Elsamadicy, AA, Babu, R, Kirkpatrick, JP, and Adamson, DC. "Radiation-induced malignant gliomas: a current review." World Neurosurgery 83, no. 4 (April 2015): 530-542. (Review) Full Text
  - Liu, J, Wu, QJ, Kirkpatrick, JP, Yin, F-F, Yuan, L, and Ge, Y. "From active shape model to active optical flow model: a shape-based approach to predicting voxel-level dose distributions in spine SBRT." Physics in medicine and biology 60, no. 5 (March 2015): N83-N92. Full Text
  - Kirkpatrick, JP, Wang, Z, Sampson, JH, McSherry, F, Herndon, JE, Allen, KJ, Duffy, E, Hoang, JK, Chang, Z, Yoo, DS, Kelsey, CR, and Yin, F-F. "Defining the optimal planning target volume in image-guided stereotactic radiosurgery of brain metastases: results of a randomized trial." International Journal of Radiation Oncology, Biology, Physics 91, no. 1 (January 2015): 100-108. Full Text
  - Liu, J, Jackie Wu, Q, Yin, FF, Kirkpatrick, JP, Cabrera, A, and Ge, Y. "An active optical flow model for dose prediction in spinal sbrt plans." Lecture Notes in Computational Vision and Biomechanics 20 (January 1, 2015): 27-35. Full Text
  - Sperduto, PW, Song, CW, Kirkpatrick, JP, and Glatstein, E. "A hypothesis: indirect cell death in the radiosurgery era." International Journal of Radiation Oncology, Biology, Physics 91, no. 1 (January 2015): 11-13. Full Text
  - Kirkpatrick, JP, and Sampson, JH. "Recurrent malignant gliomas." Seminars in radiation oncology 24, no. 4 (October 2014): 289-298. (Review) Full Text
  - Chang, Z, Kirkpatrick, JP, Wang, Z, Cai, J, Adamson, J, and Yin, F-F. "Evaluating radiation-induced white matter changes in patients treated with stereotactic radiosurgery using diffusion tensor imaging: a pilot study." Technology in Cancer Research & Treatment 13, no. 1 (February 2014): 21-28. Full Text
  - Kirkpatrick, JP, Kelsey, CR, Palta, M, Cabrera, AR, Salama, JK, Patel, P, Perez, BA, Lee, J, and Yin, F-F. "Stereotactic body radiotherapy: A critical review for non-radiation oncologists." Cancer (2014).
  - Kirkpatrick, JP, Kelsey, CR, Palta, M, Cabrera, AR, Salama, JK, Patel, P, Perez, BA, Lee, J, and Yin, FF. "Stereotactic body radiotherapy: A critical review for nonradiation oncologists." Cancer 120, no. 7 (January 1, 2014): 942-954. (Review) Full Text
  - Cabrera, AR, Cuneo, KC, Desjardins, A, Sampson, JH, McSherry, F, Herndon, JE, Peters, KB, Allen, K, Hoang, JK, Chang, Z, Craciunescu, O, Vredenburgh, JJ, Friedman, HS, and Kirkpatrick, JP. "Concurrent stereotactic radiosurgery and bevacizumab in recurrent malignant gliomas: a prospective trial." International Journal of Radiation Oncology, Biology, Physics 86, no. 5 (August 2013): 873-879. Full Text
  - Thomas, A, Niebanck, M, Wang, Z, Kirkpatrick, J, and Oldham, M. "MO-F-108-11: 3D Verification for Multifocal Single Isocenter SRS." Medical Physics 40, no. 6Part24 (June 2013): 409-null. Full Text
  - Cabrera, AR, Cuneo, KC, Desjardins, A, Sampson, JH, McSherry, F, II, JEH, Peters, KB, Allen, K, Hoang, JK, Chang, Z, Craciunescu, O, Vredenburgh, JJ, Friedman, HS, and Kirkpatrick, JP. "Concurrent stereotactic radiosurgery and bevacizumab in recurrent malignant gliomas: A prospective trial." International Journal of Radiation Oncology Biology Physics 86, no. 5 (2013): 873-879. Full Text
  - Kirkpatrick, JP, Light, KL, Walker, RM, Georgas, DL, Antoine, PA, Clough, RW, Cozart, HB, Yin, F-F, Yoo, S, and Willett, CG. "Implementing and integrating a clinically driven electronic medical record for radiation oncology in a large medical enterprise. (Published online)" Front Oncol 3 (2013): 69-. Full Text Link to Item
  - Kirkpatrick, JP, Yin, F-F, and Sampson, JH. "Radiotherapy and Radiosurgery for Tumors of the Central Nervous System." Surgical Oncology Clinics of North America (2013). Full Text
  - Kirkpatrick, JP, Yin, F-F, and Sampson, JH. "Radiotherapy and Radiosurgery for Tumors of the Central Nervous System." Surgical Oncology Clinics of North America 22, no. 3 (2013): 445-461. Full Text
  - Kirkpatrick, JP. "Oncology scan - Low-grade gliomas: Predicting and changing outcome." International Journal of Radiation Oncology Biology Physics 87, no. 2 (2013): 234-236. Full Text
  - Sperduto, PW, Kased, N, Roberge, D, Chao, ST, Shanley, R, Luo, X, Sneed, PK, Suh, J, Weil, RJ, Jensen, AW, Brown, PD, Shih, HA, Kirkpatrick, J, Gaspar, LE, Fiveash, JB, Chiang, V, Knisely, JPS, Sperduto, CM, Lin, N, and Mehta, M. "The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer." Journal of Neuro-Oncology 112, no. 3 (2013): 467-472. Full Text
  - Sperduto, PW, Kased, N, Roberge, D, Chao, ST, Shanley, R, Luo, X, Sneed, PK, Suh, J, Weil, RJ, Jensen, AW, and al, E. "The effect of tumor subtype on the time from primary diagnosis to development of brain metastases and survival in patients with breast cancer." Journal of Neuro-Oncology (2013): 1-6. Full Text
  - Oh, DS, Adamson, DC, and Kirkpatrick, JP. "Targeted radiotherapy for malignant gliomas." Curr Drug Discov Technol 9, no. 4 (December 2012): 268-279. (Review) Link to Item
  - Salama, JK, Kirkpatrick, JP, and Yin, F-F. "Stereotactic body radiotherapy treatment of extracranial metastases." Nature Reviews. Clinical Oncology 9, no. 11 (November 2012): 654-665. (Review) Full Text
  - Yuan, L, Ge, Y, Lee, WR, Yin, FF, Kirkpatrick, JP, and Wu, QJ. "Quantitative analysis of the factors which affect the interpatient organ-at-risk dose sparing variation in IMRT plans." Medical Physics 39, no. 11 (November 2012): 6868-6878. Full Text
  - Oldham, M, Thomas, A, O'Daniel, J, Juang, T, Ibbott, G, Adamovics, J, and Kirkpatrick, JP. "A quality assurance method that utilizes 3D dosimetry and facilitates clinical interpretation." Int J Radiat Oncol Biol Phys 84, no. 2 (October 1, 2012): 540-546. Full Text Link to Item
  - Cabrera, AR, Cuneo, KC, Vredenburgh, JJ, Sampson, JH, and Kirkpatrick, JP. "Stereotactic radiosurgery and bevacizumab for recurrent glioblastoma multiforme." J Natl Compr Canc Netw 10, no. 6 (June 1, 2012): 695-699. Link to Item
  - Cuneo, KC, Zagar, TM, Brizel, DM, Yoo, DS, Hoang, JK, Chang, Z, Wang, Z, Yin, FF, Das, SK, Green, S, Ready, N, Bhatti, MT, Kaylie, DM, Becker, A, Sampson, JH, and Kirkpatrick, JP. "Stereotactic radiotherapy for malignancies involving the trigeminal and facial nerves." Technol Cancer Res Treat 11, no. 3 (June 2012): 221-228. Full Text Link to Item
  - Huang, C, Ren, L, Kirkpatrick, J, and Wang, Z. "SU-E-T-645: Treatment of Multiple Brain Metastases Using Stereotactic Radiosurgery with Single-Isocenter Volumetric Modulated Arc Therapy: Comparison with Conventional Dynamic Conformal Arc and Static Beam Stereotactic Radiosurgery." Medical Physics 39, no. 6Part20 (June 2012): 3854-null. Full Text
  - Wang, Z, Newton, J, Niebanck, M, Juang, T, Kirkpatrick, J, and Oldham, M. "TU-E-BRB-09: Validation of Multi-Focal Stereotactic Radiosurgery with Volumetric Modulated Arc Therapy with High-Resolution 3D Dosimetry." Medical Physics 39, no. 6Part24 (June 2012): 3910-null. Full Text
  - Cuneo, KC, Vredenburgh, JJ, Sampson, JH, Reardon, DA, Desjardins, A, Peters, KB, Friedman, HS, Willett, CG, and Kirkpatrick, JP. "Safety and efficacy of stereotactic radiosurgery and adjuvant bevacizumab in patients with recurrent malignant gliomas." International Journal of Radiation Oncology, Biology, Physics 82, no. 5 (April 2012): 2018-2024. Full Text
  - Sperduto, PW, Kased, N, Roberge, D, Xu, Z, Shanley, R, Luo, X, Sneed, PK, Chao, ST, Weil, RJ, Suh, J, Bhatt, A, Jensen, AW, Brown, PD, Shih, HA, Kirkpatrick, J, Gaspar, LE, Fiveash, JB, Chiang, V, Knisely, JPS, Sperduto, CM, Lin, N, and Mehta, M. "Effect of tumor subtype on survival and the graded prognostic assessment for patients with breast cancer and brain metastases." International Journal of Radiation Oncology, Biology, Physics 82, no. 5 (April 2012): 2111-2117. Full Text
  - Yoo, DS, Kirkpatrick, JP, Craciunescu, O, Broadwater, G, Peterson, BL, Carroll, MD, Clough, R, MacFall, JR, Hoang, J, Scher, RL, Esclamado, RM, Dunphy, FR, Ready, NE, and Brizel, DM. "Prospective trial of synchronous bevacizumab, erlotinib, and concurrent chemoradiation in locally advanced head and neck cancer." Clin Cancer Res 18, no. 5 (March 1, 2012): 1404-1414. Full Text Link to Item
  - Sperduto, PW, Kased, N, Roberge, D, Xu, Z, Shanley, R, Luo, X, Sneed, PK, Chao, ST, Weil, RJ, Suh, J, Bhatt, A, Jensen, AW, Brown, PD, Shih, HA, Kirkpatrick, J, Gaspar, LE, Fiveash, JB, Chiang, V, Knisely, JPS, Sperduto, CM, Lin, N, and Mehta, M. "Summary report on the graded prognostic assessment: an accurate and facile diagnosis-specific tool to estimate survival for patients with brain metastases." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 30, no. 4 (February 2012): 419-425. Full Text
  - Sperduto, PW, Kased, N, Roberge, D, Xu, Z, Shanley, R, Luo, X, Sneed, PK, Chao, ST, Weil, RJ, Suh, J, Bhatt, A, Jensen, AW, Brown, PD, Shih, HA, Kirkpatrick, J, Gaspar, LE, Fiveash, JB, Chiang, V, Knisely, JPS, Sperduto, CM, Lin, N, and Mehta, M. "Reply to M.C. Chamberlain et al." Journal of Clinical Oncology 30, no. 26 (2012): 3316-3317. Full Text
  - Sperduto, PW, Sneed, PK, Roberge, D, Shanley, R, Luo, X, Weil, RJ, Suh, J, Bhatt, A, Jensen, AW, Brown, PD, Shih, HA, Kirkpatrick, J, Gaspar, LE, Fiveash, JB, Knisely, JPS, Lin, N, and Mehta, M. "In Regard to Yamamoto et al." International Journal of Radiation Oncology Biology Physics 84, no. 4 (2012): 875-876. Full Text
  - Vredenburgh, JJ, Desjardins, A, Kirkpatrick, JP, Reardon, DA, Peters, KB, Herndon, JE, Marcello, J, Bailey, L, Threatt, S, Sampson, J, Friedman, A, and Friedman, HS. "Addition of bevacizumab to standard radiation therapy and daily temozolomide is associated with minimal toxicity in newly diagnosed glioblastoma multiforme." Int J Radiat Oncol Biol Phys 82, no. 1 (January 1, 2012): 58-66. Full Text Link to Item
  - Vredenburgh, JJ, Desjardins, A, Reardon, DA, Peters, KB, Kirkpatrick, JP, II, HJE, Coan, AD, Bailey, L, Janney, D, Lu, C, and Friedman, HS. "THE ADDITION OF BEVACIZUMAB TO TEMOZOLOMIDE AND RADIATION THERAPY FOLLOWED BY BEVACIZUMAB, TEMOZOLOMIDE, AND ORAL TOPOTECAN FOR NEWLY DIAGNOSED GLIOBLASTOMA MULTIFORME." NEURO-ONCOLOGY 13 (November 2011): 89-90. Link to Item
  - Vredenburgh, JJ, Desjardins, A, Reardon, DA, Peters, KB, Herndon, JE, Marcello, J, Kirkpatrick, JP, Sampson, JH, Bailey, L, Threatt, S, Friedman, AH, Bigner, DD, and Friedman, HS. "The addition of bevacizumab to standard radiation therapy and temozolomide followed by bevacizumab, temozolomide, and irinotecan for newly diagnosed glioblastoma." Clinical Cancer Research : an Official Journal of the American Association for Cancer Research 17, no. 12 (June 2011): 4119-4124. Full Text
  - Reardon, DA, Turner, S, Peters, KB, Desjardins, A, Gururangan, S, Sampson, JH, McLendon, RE, Herndon, JE, Jones, LW, Kirkpatrick, JP, Friedman, AH, Vredenburgh, JJ, Bigner, DD, and Friedman, HS. "A review of VEGF/VEGFR-targeted therapeutics for recurrent glioblastoma." J Natl Compr Canc Netw 9, no. 4 (April 2011): 414-427. (Review) Link to Item
  - Keir, ST, Dewhirst, MW, Kirkpatrick, JP, Bigner, DD, and Batinic-Haberle, I. "Cellular redox modulator, ortho Mn(III) meso-tetrakis(N-n-hexylpyridinium-2-yl)porphyrin, MnTnHex-2-PyP(5+) in the treatment of brain tumors." Anticancer Agents Med Chem 11, no. 2 (February 2011): 202-212. Link to Item
  - Cabrera, AR, Craciunescu, O, Cuneo, KC, Chang, Z, and Kirkpatrick, JP. "Evaluating Recurrent Gliomas with Diffusion-weighted MR Imaging Before and After Concurrent Radiosurgery and Bevacizumab." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S793-S793. Full Text Link to Item
  - Cuneo, KC, Cabrera, AR, Sampson, J, Allen, K, Duffy, E, Vredenburgh, JJ, Peters, KB, Chang, Z, Desjardins, A, and Kirkpatrick, JP. "Bevacizumab and Radiosurgery for Recurrent Malignant Glioma: Toxicity Results from a Prospective Pilot Study." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S185-S185. Full Text Link to Item
  - Horton, JK, Fels, DR, Chi, JA, Kung, H, Kirkpatrick, JP, and Dewhirst, M. "Protein Pathway Activation after Ionizing Radiation in Luminal and Basal Breast Cancer Cell Lines." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S160-S161. Full Text Link to Item
  - Kirkpatrick, JP, Green, S, Zagar, T, and Wang, Z. "Balancing Tumor Kill and Normal Tissue Toxicity in Radiosurgery: Critical Impact of the Peritumoral Zone." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S866-S866. Full Text Link to Item
  - Palta, M, Riedel, RF, Vredenburgh, JJ, Cummings, TJ, Green, S, Chang, Z, and Kirkpatrick, JP. "Primary meningeal rhabdomyosarcoma." Sarcoma 2011 (January 2011): 312802-null. Full Text
  - Sperduto, PW, Chao, ST, Suh, J, Sneed, PK, Luo, X, Roberge, D, Bhatt, A, Mehta, MP, Jensen, AW, Brown, PD, Shih, H, Kirkpatrick, J, Gaspar, LE, Fiveash, JB, Chiang, V, Knisely, J, and Sperduto, CM. "Reply to Drs. mulvenna and holt." International Journal of Radiation Oncology Biology Physics 81, no. 4 (2011): 1194-1195. Full Text
  - Wang, Z, Yin, F, Chang, Z, Sampson, J, and Kirkpatrick, JP. "Imaging-Guided Localization for Stereotactic Radiosurgery of Multiple Intracranial Lesions with a Single Isocenter Setup." INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS 81, no. 2 (2011): S860-S860. Full Text Link to Item
  - Sperduto, PW, Chao, ST, Sneed, PK, Luo, X, Suh, J, Roberge, D, Bhatt, A, Jensen, AW, Brown, PD, Shih, H, Kirkpatrick, J, Schwer, A, Gaspar, LE, Fiveash, JB, Chiang, V, Knisely, J, Sperduto, CM, and Mehta, M. "Diagnosis-specific prognostic factors, indexes, and treatment outcomes for patients with newly diagnosed brain metastases: a multi-institutional analysis of 4,259 patients." International Journal of Radiation Oncology, Biology, Physics 77, no. 3 (July 2010): 655-661. Full Text
  - Chong, GT, Mukundan, S, Kirkpatrick, JP, Zomorodi, A, Sampson, JH, and Bhatti, MT. "Stereotactic radiosurgery in the treatment of a dural carotid-cavernous fistula." J Neuroophthalmol 30, no. 2 (June 2010): 138-144. Full Text Link to Item
  - Chang, Z, Wang, Z, Ma, J, O'Daniel, JC, Kirkpatrick, J, and Yin, F-F. "6D image guidance for spinal non-invasive stereotactic body radiation therapy: Comparison between ExacTrac X-ray 6D with kilo-voltage cone-beam CT." Radiother Oncol 95, no. 1 (April 2010): 116-121. Full Text Link to Item
  - Kirkpatrick, JP, van der Kogel, AJ, and Schultheiss, TE. "Radiation dose-volume effects in the spinal cord." International Journal of Radiation Oncology, Biology, Physics 76, no. 3 Suppl (March 2010): S42-S49. (Review) Full Text
  - Mayo, C, Martel, MK, Marks, LB, Flickinger, J, Nam, J, and Kirkpatrick, J. "Radiation dose-volume effects of optic nerves and chiasm." International Journal of Radiation Oncology, Biology, Physics 76, no. 3 Suppl (March 2010): S28-S35. (Review) Full Text
  - Kelsey, CR, Mukundan, S, Wang, Z, Hahn, CA, Soher, BJ, and Kirkpatrick, JP. "Assessing neurotoxicity from the low-dose radiation component of radiosurgery using magnetic resonance spectroscopy." Neuro Oncol 12, no. 2 (February 2010): 145-152. Full Text Link to Item
  - Ma, J, Chang, Z, Wang, Z, Jackie Wu, Q, Kirkpatrick, JP, and Yin, F-F. "ExacTrac X-ray 6 degree-of-freedom image-guidance for intracranial non-invasive stereotactic radiotherapy: comparison with kilo-voltage cone-beam CT." Radiother Oncol 93, no. 3 (December 2009): 602-608. Full Text Link to Item
  - Wu, QJ, Yoo, S, Kirkpatrick, JP, Thongphiew, D, and Yin, F-F. "Volumetric arc intensity-modulated therapy for spine body radiotherapy: comparison with static intensity-modulated treatment." Int J Radiat Oncol Biol Phys 75, no. 5 (December 1, 2009): 1596-1604. Full Text Link to Item
  - Kirkpatrick, JP, Brenner, DJ, and Orton, CG. "The linear-quadratic model is inappropriate to model high dose per fraction effects in radiosurgery." Medical Physics 36, no. 8 (August 2009): 3381-3384. Full Text
  - Kirkpatrick, JP, Brenner, DJ, and Orton, CG. "Point/Counterpoint. The linear-quadratic model is inappropriate to model high dose per fraction effects in radiosurgery." Medical Physics 36, no. 8 (August 2009): 3381-3384. Full Text
  - Chino, JP, Sampson, JH, Tucci, DL, Brizel, DM, and Kirkpatrick, JP. "Paraganglioma of the head and neck: long-term local control with radiotherapy." Am J Clin Oncol 32, no. 3 (June 2009): 304-307. Full Text Link to Item
  - Kirkpatrick, JP, Vredenburgh, JJ, Desjardins, A, Gururangan, S, Peters, KB, Boulton, ST, Friedman, AH, Friedman, HS, and Reardon, DA. "Phase I study of vandetanib, imatinib mesylate, and hydroxyurea for recurrent malignant glioma." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 27, no. 15_suppl (May 2009): e13007-.
  - Nelson, JW, Yoo, DS, Sampson, JH, Isaacs, RE, Larrier, NA, Marks, LB, Yin, F-F, Wu, QJ, Wang, Z, and Kirkpatrick, JP. "Stereotactic body radiotherapy for lesions of the spine and paraspinal regions." Int J Radiat Oncol Biol Phys 73, no. 5 (April 1, 2009): 1369-1375. Full Text Link to Item
  - Hahn, CA, Zhou, S-M, Raynor, R, Tisch, A, Light, K, Shafman, T, Wong, T, Kirkpatrick, J, Turkington, T, Hollis, D, and Marks, LB. "Dose-dependent effects of radiation therapy on cerebral blood flow, metabolism, and neurocognitive dysfunction." International Journal of Radiation Oncology, Biology, Physics 73, no. 4 (March 2009): 1082-1087. Full Text
  - Reese, AS, Das, SK, Kirkpatrick, JP, and Marks, LB. "Quantifying the dosimetric trade-offs when using intensity-modulated radiotherapy to treat concave targets containing normal tissues." Int J Radiat Oncol Biol Phys 73, no. 2 (February 1, 2009): 585-593. Full Text Link to Item
  - Wang, Z, Nelson, JW, Yoo, S, Wu, QJ, Kirkpatrick, JP, Marks, LB, and Yin, F-F. "Refinement of treatment setup and target localization accuracy using three-dimensional cone-beam computed tomography for stereotactic body radiotherapy." International Journal of Radiation Oncology, Biology, Physics 73, no. 2 (February 2009): 571-577. Full Text
  - Wu, QJ, Wang, Z, Kirkpatrick, JP, Chang, Z, Meyer, JJ, Lu, M, Huntzinger, C, and Yin, F-F. "Impact of collimator leaf width and treatment technique on stereotactic radiosurgery and radiotherapy plans for intra- and extracranial lesions." Radiation Oncology (London, England) 4 (January 21, 2009): 3-null. Full Text
  - Wu, QJ, Wang, Z, Kirkpatrick, JP, Chang, Z, Meyer, JJ, Lu, M, Huntzinger, C, and Yin, F-F. "Impact of collimator leaf width and treatment technique on stereotactic radiosurgery and radiotherapy plans for intra- and extracranial lesions." Radiation oncology (London, England) 4 (2009): 3--. Full Text
  - Kirkpatrick, JP, Meyer, JJ, and Marks, LB. "The linear-quadratic model is inappropriate to model high dose per fraction effects in radiosurgery." Seminars in Radiation Oncology 18, no. 4 (October 2008): 240-243. Full Text
  - Boyd, JA, Hubbs, JL, Hollis, DR, Kirkpatrick, JP, Kim, DW, Marks, LB, and Kelsey, CR. "The actuarial incidence of brain metastases in 975 patients undergoing surgery for early-stage lung cancer." J Clin Oncol 26, no. 15_suppl (May 20, 2008): 8094-. Link to Item
  - Boyd, JA, Hubbs, JL, Hollis, DR, Kirkpatrick, JP, Kim, DW, Marks, LB, and Kelsey, CR. "The actuarial incidence of brain metastases in 975 patients undergoing surgery for early-stage lung cancer." JOURNAL OF CLINICAL ONCOLOGY 26, no. 15 (May 20, 2008). Full Text Link to Item
  - Kirkpatrick, JP, Rich, JN, Vredenburgh, JJ, Desjardins, A, Quinn, JA, Gururangan, S, Sathornsumetee, S, Egorin, MJ, Friedman, HS, and Reardon, DA. "Final report: Phase I trial of imatinib mesylate, hydroxyurea, and vatalanib for patients with recurrent malignant glioma (MG)." JOURNAL OF CLINICAL ONCOLOGY 26, no. 15 (May 20, 2008). Link to Item
  - Kirkpatrick, JP, Rich, JN, Vredenburgh, JJ, Desjardins, A, Quinn, JA, Gururangan, S, Sathornsumetee, S, Egorin, MJ, Friedman, HS, and Reardon, DA. "Final report: Phase I trial of imatinib mesylate, hydroxyurea, and vatalanib for patients with recurrent malignant glioma (MG)." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 26, no. 15_suppl (May 2008): 2057-.
  - Yin, F-F, Wang, Z, Yoo, S, Wu, QJ, Kirkpatrick, J, Larrier, N, Meyer, J, Willett, CG, and Marks, LB. "Integration of cone-beam CT in stereotactic body radiation therapy." Technology in Cancer Research & Treatment 7, no. 2 (April 2008): 133-139. Full Text
  - Kirkpatrick, JP, and Dewhirst, MW. "Analytic solution to steady-state radial diffusion of a substrate with first-order reaction kinetics in the tissue of a Krogh's cylinder." Radiat Res 169, no. 3 (March 2008): 350-354. Full Text Link to Item
  - Kirkpatrick, JP, Rabbani, ZN, Bentley, RC, Hardee, ME, Karol, S, Meyer, J, Oosterwijk, E, Havrilesky, L, Secord, AA, Vujaskovic, Z, Dewhirst, MW, and Jones, EL. "Elevated CAIX Expression is Associated with an Increased Risk of Distant Failure in Early-Stage Cervical Cancer. (Published online)" Biomark Insights 3 (February 1, 2008): 45-55. Link to Item
  - Scott, AW, Cummings, TJ, Kirkpatrick, JP, and Mruthyunjaya, P. "Choroidal metastasis of follicular thyroid adenocarcinoma diagnosed by 25-gauge transretinal biopsy." Ann Ophthalmol (Skokie) 40, no. 2 (2008): 110-112. Link to Item
  - Kasibhatla, M, Kirkpatrick, JP, and Brizel, DM. "How much radiation is the chemotherapy worth in advanced head and neck cancer?." Int J Radiat Oncol Biol Phys 68, no. 5 (August 1, 2007): 1491-1495. Full Text Link to Item
  - Miles, EF, Kelsey, CR, Kirkpatrick, JP, and Marks, LB. "Estimating the magnitude and field-size dependence of radiotherapy-induced mortality and tumor control after postoperative radiotherapy for non-small-cell lung cancer: calculations from clinical trials." Int J Radiat Oncol Biol Phys 68, no. 4 (July 15, 2007): 1047-1052. Full Text Link to Item
  - Fleckenstein, K, Zgonjanin, L, Chen, L, Rabbani, Z, Jackson, IL, Thrasher, B, Kirkpatrick, J, Foster, WM, and Vujaskovic, Z. "Temporal onset of hypoxia and oxidative stress after pulmonary irradiation." International Journal of Radiation Oncology, Biology, Physics 68, no. 1 (May 2007): 196-204. Full Text
  - Soper, JT, Spillman, M, Sampson, JH, Kirkpatrick, JP, Wolf, JK, and Clarke-Pearson, DL. "High-risk gestational trophoblastic neoplasia with brain metastases: individualized multidisciplinary therapy in the management of four patients." Gynecol Oncol 104, no. 3 (March 2007): 691-694. Full Text Link to Item
  - Kirkpatrick, JP. "Tumor hypoxia and prognosis in human gliomas." Cancer J 12, no. 6 (November 2006): 451-454. Link to Item
  - Oldham, M, Sakhalkar, H, Oliver, T, Wang, YM, Kirpatrick, J, Cao, Y, Badea, C, Johnson, GA, and Dewhirst, M. "Three-dimensional imaging of xenograft tumors using optical computed and emission tomography." Medical Physics 33, no. 9 (September 2006): 3193-3202. Full Text
  - Yin, F-F, Das, S, Kirkpatrick, J, Oldham, M, Wang, Z, and Zhou, S-M. "Physics and imaging for targeting of oligometastases." Semin Radiat Oncol 16, no. 2 (April 2006): 85-101. (Review) Full Text Link to Item
  - Hardee, ME, Rabbani, ZN, Arcasoy, MO, Kirkpatrick, JP, Vujaskovic, Z, Dewhirst, MW, and Blackwell, KL. "Erythropoietin inhibits apoptosis in breast cancer cells via an Akt-dependent pathway without modulating in vivo chemosensitivity." Mol Cancer Ther 5, no. 2 (February 2006): 356-361. Full Text Link to Item
  - Kirkpatrick, JP, Hardee, ME, Snyder, SA, Peltz, CM, Zhao, Y, Brizel, DM, Dewhirst, MW, and Blackwell, KL. "The effect of darbepoetin alfa on growth, oxygenation and radioresponsiveness of a breast adenocarcinoma." Radiat Res 165, no. 2 (February 2006): 192-201. Link to Item
  - Koontz, BF, Kirkpatrick, JP, Clough, RW, Prosnitz, RG, Gockerman, JP, Moore, JO, and Prosnitz, LR. "Combined-modality therapy versus radiotherapy alone for treatment of early-stage Hodgkin's disease: cure balanced against complications." J Clin Oncol 24, no. 4 (February 1, 2006): 605-611. Full Text Link to Item
  - Hardee, ME, Arcasoy, MO, Blackwell, KL, Kirkpatrick, JP, and Dewhirst, MW. "Erythropoietin biology in cancer." Clin Cancer Res 12, no. 2 (January 15, 2006): 332-339. (Review) Full Text Link to Item
  - Kirkpatrick, JP, and Friedman, AH. "Multisession CyberKnife radiosurgery for intramedullary spinal cord arteriovenous malformations: Commentary." Neurosurgery 58, no. 6 (2006): 1089--. Full Text
  - Meyer, JJ, Marks, LB, Halperin, EC, and Kirkpatrick, JP. "Kinetic modeling of tumor growth and dissemination in the craniospinal axis: implications for craniospinal irradiation." Radiation Oncology (London, England) 1 (January 2006): 48-null. Full Text
  - Hardee, ME, Kirkpatrick, JP, Shan, S, Snyder, SA, Vujaskovic, Z, Rabbani, ZN, Dewhirst, MW, and Blackwell, KL. "Human recombinant erythropoietin (rEpo) has no effect on tumour growth or angiogenesis." Br J Cancer 93, no. 12 (December 12, 2005): 1350-1355. Full Text Link to Item
  - Kirkpatrick, JP, and Anscher, MS. "Radiotherapy for locally recurrent prostate cancer." Clinical Advances in Hematology & Oncology : H&O 3, no. 12 (December 2005): 933-942. (Review)
  - Liu, S, Wang, H, Yang, Z, Kon, T, Zhu, J, Cao, Y, Li, F, Kirkpatrick, J, Nicchitta, CV, and Li, C-Y. "Enhancement of cancer radiation therapy by use of adenovirus-mediated secretable glucose-regulated protein 94/gp96 expression." Cancer Res 65, no. 20 (October 15, 2005): 9126-9131. Full Text Link to Item
  - Zhang, X, Kon, T, Wang, H, Li, F, Huang, Q, Rabbani, ZN, Kirkpatrick, JP, Vujaskovic, Z, Dewhirst, MW, and Li, C-Y. "Enhancement of hypoxia-induced tumor cell death in vitro and radiation therapy in vivo by use of small interfering RNA targeted to hypoxia-inducible factor-1alpha." Cancer Res 64, no. 22 (November 15, 2004): 8139-8142. Full Text Link to Item
  - Hardee, ME, Kirkpatrick, JP, Snyder, S, Shan, S, Vujaskovic, Z, Rabbani, ZN, Dewhirst, MW, and Blackwell, KL. "Erythropoietin (EPO) has no direct effect on tumor growth or angiogenesis in animal models." Journal of clinical oncology : official journal of the American Society of Clinical Oncology 22, no. 14_suppl (July 2004): 9530-.
  - Kirkpatrick, JP, Cárdenas-Navia, LI, and Dewhirst, MW. "Predicting the effect of temporal variations in PO2 on tumor radiosensitivity." Int J Radiat Oncol Biol Phys 59, no. 3 (July 1, 2004): 822-833. Full Text Link to Item
  - Huang, Q, Zhang, X, Wang, H, Yan, B, Kirkpatrick, J, Dewhrist, MW, and Li, C-Y. "A novel conditionally replicative adenovirus vector targeting telomerase-positive tumor cells." Clin Cancer Res 10, no. 4 (February 15, 2004): 1439-1445. Link to Item
  - Kirkpatrick, JP, and Marks, LB. "Modeling killing and repopulation kinetics of subclinical cancer: direct calculations from clinical data." International Journal of Radiation Oncology, Biology, Physics 58, no. 2 (February 2004): 641-654. Full Text
  - Blackwell, KL, Kirkpatrick, JP, Snyder, SA, Broadwater, G, Farrell, F, Jolliffe, L, Brizel, DM, and Dewhirst, MW. "Human recombinant erythropoietin significantly improves tumor oxygenation independent of its effects on hemoglobin." Cancer Res 63, no. 19 (October 1, 2003): 6162-6165. Link to Item
  - Kang, SK, Kirkpatrick, JP, and Halperin, EC. "Low-dose radiation for posttransplant lymphoproliferative disorder." American Journal of Clinical Oncology 26, no. 2 (April 2003): 210-214. Full Text
  - Kirkpatrick, JP, Brizel, DM, and Dewhirst, MW. "A mathematical model of tumor oxygen and glucose mass transport and metabolism with complex reaction kinetics." Radiat Res 159, no. 3 (March 2003): 336-344. Link to Item
  - Braaten, JV, Handt, S, Jerome, WG, Kirkpatrick, J, Lewis, JC, and Hantgan, RR. "Regulation of fibrinolysis by platelet-released plasminogen activator inhibitor 1: light scattering and ultrastructural examination of lysis of a model platelet-fibrin thrombus." Blood 81, no. 5 (March 1993): 1290-1299.
  - Kirkpatrick, JP, McIntire, LV, Moake, JL, and Cimo, PL. "Differential effects of cytochalasin B on platelet release, aggregation and contractility: evidence against a contractile mechanism for the release of platelet granular contents." Thromb Haemost 42, no. 5 (February 29, 1980): 1483-1489. Link to Item
  - Kirkpatrick, JP, McIntire, LV, Moake, JL, and Peterson, DM. "Metabolic requirements of contractile force generation in platelet rich plasma - a rheological study." Biorheology 17, no. 5-6 (1980): 411-418. Link to Item
  - Kirkpatrick, JP, McIntire, LV, and Characklis, WG. "Mass and heat transfer in a circular tube with biofouling." Water Research 14, no. 2 (1980): 117-127. Full Text
  - Kirkpatrick, JP, McIntire, LV, Moake, JL, and Peterson, DL. "DYNAMIC RHEOLOGICAL STUDIES OF COAGULATION AND FIBRINOLYSIS." Journal of Rheology 23, no. 6 (1979): 769-787. Full Text
  - Kirkpatrick, JP, McIntire, LV, and Moake, JL. "Streptokinase-induced degradation of crosslinked and uncrosslinked clots." Thromb Res 13, no. 3 (September 1978): 569-575. Link to Item

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