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Comparison of Local Medicare Guidance and Medicare Advantage Plans for Stereotactic Radiosurgery for Brain Metastases.

Publication ,  Journal Article
LaBella, D; Battershall, E; Reitman, ZJ; Floyd, SR; Vaios, EJ; Kirkpatrick, JP; Sperduto, P; Mullikin, TC
Published in: Adv Radiat Oncol
February 2026

PURPOSE: Medicare Advantage operates under a capitated payment model, where Medicare Advantage Organizations (MAOs) must provide services that meet or exceed Medicare Parts A and B standards, ensuring actuarial equivalence. MAOs are mandated to base their coverage determinations on medical necessity, aligning with Medicare's national and local coverage determinations (LCD) policies. METHODS AND MATERIALS: This study evaluates coverage policies for stereotactic radiosurgery (SRS) for brain metastases (BM) across our institution's local LCD and various MAOs, including Cigna, Aetna, UnitedHealthcare, Humana, and Anthem. The CMS LCD L39553 (CMS) serves as the benchmark, deeming SRS medically necessary for new BM and repeat BM therapy if the patient has each of the following: good performance status (Karnofsky Performance Status ≥70 or Eastern Cooperative Oncology Group Performance Status 0-2), absence of leptomeningeal metastases, and no primary diagnosis of lymphoma, germ cell tumor, or small cell carcinoma. For repeat BM, CMS also requires stable extracranial disease and a life expectancy over 6 months. Additionally, SRS may be indicated for relapses in previously irradiated cranial fields to minimize normal tissue injury. Five MAO policies were reviewed, revealing alignment with LCD criteria in several areas but also presenting additional, sometimes more restrictive, requirements. RESULTS: For new BM, all MAOs required good performance status, with most also considering histology and absence of leptomeningeal metastases. Some MAOs introduced criteria like systemic therapy options, lesion number/volume, and BM size. For repeat BM, most MAOs required stable extracranial disease and occasionally considered life expectancy. Additional criteria included the number of BM over a year and postoperative SRS guidelines for lesion size and number. CONCLUSIONS: Despite general concordance, the added criteria by MAOs could impose more stringent requirements than CMS, potentially resulting in coverage denials. It is important that MAO policies remain consistent with evidence-based guidelines to avoid disparities that could impact patient treatments.

Duke Scholars

Published In

Adv Radiat Oncol

DOI

ISSN

2452-1094

Publication Date

February 2026

Volume

11

Issue

2

Start / End Page

101974

Location

United States

Related Subject Headings

  • 3211 Oncology and carcinogenesis
 

Citation

APA
Chicago
ICMJE
MLA
NLM
LaBella, D., Battershall, E., Reitman, Z. J., Floyd, S. R., Vaios, E. J., Kirkpatrick, J. P., … Mullikin, T. C. (2026). Comparison of Local Medicare Guidance and Medicare Advantage Plans for Stereotactic Radiosurgery for Brain Metastases. Adv Radiat Oncol, 11(2), 101974. https://doi.org/10.1016/j.adro.2025.101974
LaBella, Dominic, Eileen Battershall, Zachary J. Reitman, Scott R. Floyd, Eugene J. Vaios, John P. Kirkpatrick, Paul Sperduto, and Trey C. Mullikin. “Comparison of Local Medicare Guidance and Medicare Advantage Plans for Stereotactic Radiosurgery for Brain Metastases.Adv Radiat Oncol 11, no. 2 (February 2026): 101974. https://doi.org/10.1016/j.adro.2025.101974.
LaBella D, Battershall E, Reitman ZJ, Floyd SR, Vaios EJ, Kirkpatrick JP, et al. Comparison of Local Medicare Guidance and Medicare Advantage Plans for Stereotactic Radiosurgery for Brain Metastases. Adv Radiat Oncol. 2026 Feb;11(2):101974.
LaBella, Dominic, et al. “Comparison of Local Medicare Guidance and Medicare Advantage Plans for Stereotactic Radiosurgery for Brain Metastases.Adv Radiat Oncol, vol. 11, no. 2, Feb. 2026, p. 101974. Pubmed, doi:10.1016/j.adro.2025.101974.
LaBella D, Battershall E, Reitman ZJ, Floyd SR, Vaios EJ, Kirkpatrick JP, Sperduto P, Mullikin TC. Comparison of Local Medicare Guidance and Medicare Advantage Plans for Stereotactic Radiosurgery for Brain Metastases. Adv Radiat Oncol. 2026 Feb;11(2):101974.
Journal cover image

Published In

Adv Radiat Oncol

DOI

ISSN

2452-1094

Publication Date

February 2026

Volume

11

Issue

2

Start / End Page

101974

Location

United States

Related Subject Headings

  • 3211 Oncology and carcinogenesis