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Paul Wayne Sperduto

Adjunct Professor in the Department of Radiation Oncology
Radiation Oncology
30 Duke Medicine Circle, Box 3085, Durham, NC 27710
30 Duke Medicine Circle, Box 3085, Durham, NC 27710

Overview


I am a board-certified radiation oncologist, have been active in clinical research and am now an adjunct professor of radiation oncology at Duke and senior editor of the 2022 textbook, Khan’s Treatment Planning in Radiation Oncology, 5thedition. My research focus involves the treatment and prognosis of patients with brain metastases.

Current Appointments & Affiliations


Adjunct Professor in the Department of Radiation Oncology · 2022 - Present Radiation Oncology, Clinical Science Departments

Recent Publications


Validation of the graded prognostic assessment and recursive partitioning analysis as prognostic tools using a modern cohort of patients with brain metastases.

Journal Article Neurooncol Pract · December 2024 BACKGROUND: Prognostic indices for patients with brain metastases (BM) are needed to individualize treatment and stratify clinical trials. Two frequently used tools to estimate survival in patients with BM are the recursive partitioning analysis (RPA) and ... Full text Link to item Cite

Concurrent Lapatinib With Brain Radiation Therapy in Patients With HER2+ Breast Cancer With Brain Metastases: NRG Oncology-KROG/RTOG 1119 Phase 2 Randomized Trial.

Journal Article Int J Radiat Oncol Biol Phys · April 1, 2024 PURPOSE: Lapatinib plus whole brain radiation therapy (WBRT) or stereotactic radiosurgery (SRS) was hypothesized to improve the 12-week intracranial complete response (CR) rate compared with either option of radiation therapy (RT) alone for patients with b ... Full text Link to item Cite
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Education, Training & Certifications


Duke University, School of Medicine · 1984 M.D.
Duke University · 1979 B.A.