John Daniel Shelburne

Our group has maintained and refined a state of the art analytical electron microscopy laboratory. Research by different members of our group focuses on the following major areas: pathophysiology of the pneumoconioses, cell pathology of laser damage, and correlative microprobe analysis (comparing conventional microprobe analysis with new techniques such as using the free electron laser or FEL).

Current Appointments & Affiliations

Professor Emeritus of Pathology · 2008 - Present Pathology, Clinical Science Departments

Recent Publications

Inspissation of pancreatic zymogen material in cystic fibrosis.

Journal Article Ultrastruct Pathol · 2003 Cystic fibrosis is characterized by the elaboration of abnormal, thick, tenacious mucus resulting in obstructive disease in sites such as the lung and pancreas. In the pancreas, acinar plugs of mucus have been reported as the earliest recognizable morpholo ... Link to item Cite

Special techniques in diagnostic electron microscopy.

Journal Article Hum Pathol · December 1998 The power of electron microscopy as a diagnostic tool can be amplified considerably by the application of ancillary preparative and analytic methods. Subcellular chemistry and structure can be examined by various forms of microprobe analysis and by special ... Full text Link to item Cite

Histology of conjunctival vascular endothelium after filtering surgery with mitomycin C in rabbits.

Journal Article Can J Ophthalmol · October 1996 OBJECTIVE: To examine histologic changes in conjunctival vasculature during the first 72 hours following filtering surgery with adjunctive mitomycin C in rabbits. DESIGN: Thirty-six New Zealand white rabbits underwent unilateral posterior lip sclerectomy. ... Link to item Cite

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Education, Training & Certifications

Duke University · 1972 M.D.

Duke University · 1971 Ph.D.