Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Fellowship in Hematology-Oncology, Medicine, Duke University School of Medicine 2008 - 2011
  • Residency, Medicine, University of Washington 2005 - 2008
  • M.D., University of Chicago 2005
• 

  Duke Appointment History

  • Medical Instructor in the Department of Medicine, Medicine, Medical Oncology, Medicine 2011 - 2013
  • Instructor Temporary in the Department of Medicine, Medicine, Medical Oncology, Medicine 2011
• Research
• 

  Selected Grants

  • Nektar awarded by Nektar Therapeutics 2018 - 2023
  • AbbVie M14-064 awarded by AbbVie Inc. 2018 - 2023
  • AbbVie M16-438 awarded by AbbVie Inc. 2018 - 2023
  • Seattle Genetics-SGN2FF001: A Phase 1, multicenter, open-label, dose-escalation study awarded by Seattle Genetics, Inc 2017 - 2022
  • A Multicenter, phase I open-label dose escalation study of ABBV-085 an antibody drug conjugated in subjects with advanced solid tumors. awarded by AbbVie Inc. 2016 - 2021
  • A Phase 3 Randomized double blined placebo controlled study to evaluate the efficacy and safety of GS-5745 conbimed with mFOLFAX6 as first line treatment in patients with advanced gastric or gastroeso awarded by Gilead Sciences, Inc. 2016 - 2021
  • An open label multicenter dose escalation and expansion phase IB study to evaluste the safety pharmacokinetics and therapeutic activity awarded by F. Hoffmann-La Roche Ltd 2016 - 2021
  • Amgen 510 awarded by Amgen, Inc. 2019 - 2021
  • Phase Ib study of Atezolizumab in combination with Bevacizumab in solid tumor patients awarded by Genentech, Inc. 2017 - 2021
  • A phase I open label dose escalation and dose-expansion study to evaluate the safety toloerability pharmcokinetics immunogenicity and antitumor activate of Medi-9447 alone and in combination with MEDI awarded by MedImmune, Inc. 2015 - 2020
  • Mountaineer-Phase ll (ACCRU) awarded by Academic and Community Cancer Research United 2017 - 2020
  • Cabozantinib (XL184) with panitumamab in KRAS wild-type metastatic colorectal cancer with pharmacodynamic studies, XL184 awarded by Exelixis, Inc 2014 - 2020
  • A two part phase I multicenter ipen label study of DKN-01 in combination with weekly paclitaxel; Arm A; A dose awarded by Leap Therapeutics, Inc. 2014 - 2020
  • Duke-UNC-Wash U Partnership for Early Phase Clinical Trials in Cancer awarded by National Institutes of Health 2014 - 2020
  • A Multicenter Phase I/Ib open label dose escalation study of ABBV-399, and antibody drug conjugate, in subjects with adv awarded by AbbVie Inc. 2014 - 2020
  • A phase 1 first in human open labe dose escalation study of MGD007 a humanized gpA33 x CD3 dual affinity retargeted awarded by MacroGenics, Inc. 2014 - 2019
  • A Multicenter phase 1/1b open label dose escalation study of ABT-165 a dual variable domain immunoglobin in subject with awarded by AbbVie Inc. 2013 - 2019
  • BP29541 awarded by F. Hoffmann-La Roche Ltd 2018
  • A randomized double blinded placebo controlled phase III study of adjuvant Regorafenib versus awarded by Bayer Healthcare Pharmaceuticals Inc 2013 - 2018
  • A Phase ia/b dose escalation study of the safety pharmacokinetics and pharmacodynamics of OMP-131-R10 in advanced solid tumors and in combination awarded by OncoMed Pharmaceuticals 2016 - 2018
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Bekaii-Saab, T, Kim, R, Kim, TW, Manuel O'Connor, J, Strickler, JH, Malka, D, Sartore-Bianchi, A, Bi, F, Yamaguchi, K, Yoshino, T, and Prager, GW. "Third- or Later-line Therapy for Metastatic Colorectal Cancer: Reviewing Best Practice." Clinical Colorectal Cancer 18, no. 1 (March 1, 2019): E117-E129. (Review)  Full Text  Link to Item
    • Bekaii-Saab, T, Kim, R, Kim, TW, O'Connor, JM, Strickler, JH, Malka, D, Sartore-Bianchi, A, Bi, F, Yamaguchi, K, Yoshino, T, and Prager, GW. "Third- or Later-line Therapy for Metastatic Colorectal Cancer: Reviewing Best Practice." Clinical Colorectal Cancer 18, no. 1 (March 2019): e117-e129. (Review)  Full Text
    • Parseghian, CM, Loree, JM, Morris, VK, Liu, X, Clifton, KK, Napolitano, S, Henry, JT, Pereira, AA, Vilar, E, Johnson, B, Kee, B, Raghav, K, Dasari, A, Wu, J, Garg, N, Raymond, VM, Banks, KC, Talasaz, AA, Lanman, RB, Strickler, JH, Hong, DS, Corcoran, RB, Overman, MJ, and Kopetz, S. "Anti-EGFR-resistant clones decay exponentially after progression: implications for anti-EGFR re-challenge." Annals of Oncology : Official Journal of the European Society for Medical Oncology 30, no. 2 (February 2019): 243-249.  Full Text
    • Graham, CN, Christodoulopoulou, A, Knox, HN, Sabatelli, L, Hechmati, G, Garawin, T, and Strickler, JH. "A within-trial cost-effectiveness analysis of panitumumab compared with bevacizumab in the first-line treatment of patients with wild-type RAS metastatic colorectal cancer in the US." Journal of Medical Economics 21, no. 11 (November 2018): 1075-1083.  Full Text
    • Strickler, JH, Weekes, CD, Nemunaitis, J, Ramanathan, RK, Heist, RS, Morgensztern, D, Angevin, E, Bauer, TM, Yue, H, Motwani, M, Parikh, A, Reilly, EB, Afar, D, Naumovski, L, and Kelly, K. "First-in-Human Phase I, Dose-Escalation and -Expansion Study of Telisotuzumab Vedotin, an Antibody-Drug Conjugate Targeting c-Met, in Patients With Advanced Solid Tumors." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 36, no. 33 (November 2018): 3298-3306.  Full Text
    • Strickler, John H. “EGFR Amplification as a Target in Gastroesophageal Adenocarcinoma: Do Anti-EGFR Therapies Deserve a Second Chance?.” Cancer Discovery 8, no. 6 (June 2018): 679–81. https://doi.org/10.1158/2159-8290.cd-18-0191.
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    • Strickler, JH, Loree, JM, Ahronian, LG, Parikh, AR, Niedzwiecki, D, Pereira, AAL, McKinney, M, Korn, WM, Atreya, CE, Banks, KC, Nagy, RJ, Meric-Bernstam, F, Lanman, RB, Talasaz, A, Tsigelny, IF, Corcoran, RB, and Kopetz, S. "Genomic Landscape of Cell-Free DNA in Patients with Colorectal Cancer." Cancer Discovery 8, no. 2 (February 2018): 164-173.  Full Text
    • Jia, J, Morse, MA, Nagy, RJ, Lanman, RB, and Strickler, JH. "Cell-Free DNA Profiling to Discover Mechanisms of Exceptional Response to Cabozantinib Plus Panitumumab in a Patient With Treatment Refractory Metastatic Colorectal Cancer." Frontiers in Oncology 8 (January 2018): 305-null.  Full Text
    • Tachibana, M, Papadopoulos, KP, Strickler, JH, Puzanov, I, Gajee, R, Wang, Y, and Zahir, H. "Evaluation of the pharmacokinetic drug interaction potential of tivantinib (ARQ 197) using cocktail probes in patients with advanced solid tumours." British Journal of Clinical Pharmacology 84, no. 1 (January 2018): 112-121.  Full Text
    • Strickler, John H., Christina Wu, and Tanios Bekaii-Saab. “Targeting BRAF in metastatic colorectal cancer: Maximizing molecular approaches..” Cancer Treatment Reviews 60 (November 2017): 109–19. https://doi.org/10.1016/j.ctrv.2017.08.006.
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    • Zhu, Jason, and John H. Strickler. “Clinical applications of liquid biopsies in gastrointestinal oncology..” Journal of Gastrointestinal Oncology 7, no. 5 (October 2016): 675–86. https://doi.org/10.21037/jgo.2016.08.08.
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    • Balaban, EP, Mangu, PB, Khorana, AA, Shah, MA, Mukherjee, S, Crane, CH, Javle, MM, Eads, JR, Allen, P, Ko, AH, Engebretson, A, Herman, JM, Strickler, JH, Benson, AB, Urba, S, and Yee, NS. "Locally Advanced, Unresectable Pancreatic Cancer: American Society of Clinical Oncology Clinical Practice Guideline." Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 34, no. 22 (August 2016): 2654-2668.  Full Text
    • Zhang, T, Boominathan, R, Foulk, B, Rao, C, Kemeny, G, Strickler, JH, Abbruzzese, JL, Harrison, MR, Hsu, DS, Healy, P, Li, J, Pi, C, Prendergast, KM, Hobbs, C, Gemberling, S, George, DJ, Hurwitz, HI, Connelly, M, Garcia-Blanco, MA, and Armstrong, AJ. "Development of a Novel c-MET-Based CTC Detection Platform." Mol Cancer Res 14, no. 6 (June 2016): 539-547.  Full Text  Open Access Copy  Link to Item
    • Roe, MT, Cyr, DD, Eckart, D, Schulte, PJ, Morse, MA, Blackwell, KL, Ready, NE, Zafar, SY, Beaven, AW, Strickler, JH, Onken, JE, Winters, KJ, Houterloot, L, Zamoryakhin, D, Wiviott, SD, White, HD, Prabhakaran, D, Fox, KAA, Armstrong, PW, Ohman, EM, and TRILOGY ACS Investigators, . "Ascertainment, classification, and impact of neoplasm detection during prolonged treatment with dual antiplatelet therapy with prasugrel vs. clopidogrel following acute coronary syndrome." European Heart Journal 37, no. 4 (January 2016): 412-422.  Full Text
    • Zhu, J, Strosberg, JR, Dropkin, E, and Strickler, JH. "Treatment of High-Grade Metastatic Pancreatic Neuroendocrine Carcinoma with FOLFIRINOX." Journal of Gastrointestinal Cancer 46, no. 2 (June 2015): 166-169.  Full Text
    • Hurwitz, Herbert I., David C. Smith, Henry C. Pitot, Jeffrey M. Brill, Rashmi Chugh, Elisabeth Rouits, Joseph Rubin, et al. “Safety, pharmacokinetics, and pharmacodynamic properties of oral DEBIO1143 (AT-406) in patients with advanced cancer: results of a first-in-man study..” Cancer Chemotherapy and Pharmacology 75, no. 4 (April 2015): 851–59. https://doi.org/10.1007/s00280-015-2709-8.
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    • Hurwitz, HI, Smith, DC, Pitot, HC, Brill, JM, Chugh, R, Rouits, E, Rubin, J, Strickler, J, Vuagniaux, G, Sorensen, JM, and Zanna, C. "Safety, pharmacokinetics, and pharmacodynamic properties of oral DEBIO1143 (AT-406) in patients with advanced cancer: Results of a first-in-man study." Cancer Chemotherapy and Pharmacology 75, no. 4 (January 1, 2015): 851-859.  Full Text
    • Rangwala, F, Bendell, JC, Kozloff, MF, Arrowood, CC, Dellinger, A, Meadows, J, Tourt-Uhlig, S, Murphy, J, Meadows, KL, Starr, A, Broderick, S, Brady, JC, Cushman, SM, Morse, MA, Uronis, HE, Hsu, SD, Zafar, SY, Wallace, J, Starodub, AN, Strickler, JH, Pang, H, Nixon, AB, and Hurwitz, HI. "Phase I study of capecitabine, oxaliplatin, bevacizumab, and everolimus in advanced solid tumors." Investigational New Drugs 32, no. 4 (August 2014): 700-709.  Full Text
    • Strickler, JH, McCall, S, Nixon, AB, Brady, JC, Pang, H, Rushing, C, Cohn, A, Starodub, A, Arrowood, C, Haley, S, Meadows, KL, Morse, MA, Uronis, HE, Blobe, GC, Hsu, SD, Zafar, SY, and Hurwitz, HI. "Phase I study of dasatinib in combination with capecitabine, oxaliplatin and bevacizumab followed by an expanded cohort in previously untreated metastatic colorectal cancer." Invest New Drugs 32, no. 2 (April 2014): 330-339.  Full Text  Link to Item
    • Nussbaum, Daniel P., Syamal D. Bhattacharya, Xiaoyin Jiang, Diana M. Cardona, John H. Strickler, and Dan G. Blazer. “Gastroesophageal heterotopia and HER2/neu overexpression in an adenocarcinoma arising from a small bowel duplication..” Archives of Pathology & Laboratory Medicine 138, no. 3 (March 2014): 428–31. https://doi.org/10.5858/arpa.2012-0523-cr.
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    • Strickler, J. H., and H. I. Hurwitz. “Palliative Treatment of Metastatic Colorectal Cancer: What is the Optimal Approach?.” Current Oncology Reports 16, no. 1 (2014): 1–8.
    • Strickler, J. H., and H. I. Hurwitz. “Palliative treatment of metastatic colorectal cancer: what is the optimal approach?.” Current Oncology Reports 16, no. 1 (2014). https://doi.org/10.1007/s11912-013-0363-z.
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    • Rangwala, F, Bendell, JC, Kozloff, MF, Arrowood, CC, Dellinger, A, Meadows, J, Tourt-Uhlig, S, Murphy, J, Meadows, KL, Starr, A, Broderick, S, Brady, JC, Cushman, SM, Morse, MA, Uronis, HE, Hsu, SD, Zafar, SY, Wallace, J, Starodub, AN, Strickler, JH, Pang, H, Nixon, AB, and Hurwitz, HI. "Phase I study of capecitabine, oxaliplatin, bevacizumab, and everolimus in advanced solid tumors." Investigational New Drugs 32, no. 4 (January 1, 2014): 700-709.  Full Text
    • Strickler, JH, McCall, S, Nixon, AB, Brady, JC, Pang, H, Rushing, C, Cohn, A, Starodub, A, Arrowood, C, Haley, S, Meadows, KL, Morse, MA, Uronis, HE, Blobe, GC, Hsu, SD, Zafar, SY, and Hurwitz, HI. "Phase i study of dasatinib in combination with capecitabine, oxaliplatin and bevacizumab followed by an expanded cohort in previously untreated metastatic colorectal cancer." Investigational New Drugs 32, no. 2 (January 1, 2014): 330-339.  Full Text
    • Strickler, JH, and Hurwitz, HI. "Palliative treatment of metastatic colorectal cancer: what is the optimal approach?." Current Oncology Reports 16, no. 1 (January 2014): 363-null. (Review)  Full Text
    • Strickler, JH, and Hurwitz, HI. "Palliative treatment of metastatic colorectal cancer: What is the optimal approach? Topical collection on gastrointestinal cancers." Current Oncology Reports 16, no. 1 (January 1, 2014).  Full Text
    • Tachibana, M, Papadopoulos, KP, Strickler, J, Puzanov, I, Gajee, R, Wang, Y, and Zahir, H. "Abstract C85: Drug interaction study of tivantinib in cancer subjects using a cocktail approach." Drug Metabolism, Transport, and Biodistribution (November 2013).  Full Text
    • Roe, MT, Armstrong, PW, Fox, KAA, White, HD, Prabhakaran, D, Goodman, SG, Cornel, JH, Bhatt, DL, Clemmensen, P, Martinez, F, Ardissino, D, Nicolau, JC, Boden, WE, Gurbel, PA, Ruzyllo, W, Dalby, AJ, McGuire, DK, Leiva-Pons, JL, Parkhomenko, A, Gottlieb, S, Topacio, GO, Hamm, C, Pavlides, G, Goudev, AR, Oto, A, Tseng, C-D, Merkely, B, Gasparovic, V, Corbalan, R, Cinteză, M, McLendon, RC, Winters, KJ, Brown, EB, Lokhnygina, Y, Aylward, PE, Huber, K, Hochman, JS, Ohman, EM, and TRILOGY ACS Investigators, . "Prasugrel versus clopidogrel for acute coronary syndromes without revascularization." The New England Journal of Medicine 367, no. 14 (October 2012): 1297-1309.  Full Text
    • Strickler, JH, Starodub, AN, Jia, J, Meadows, KL, Nixon, AB, Dellinger, A, Morse, MA, Uronis, HE, Marcom, PK, Zafar, SY, Haley, ST, and Hurwitz, HI. "Phase I study of bevacizumab, everolimus, and panobinostat (LBH-589) in advanced solid tumors." Cancer Chemotherapy and Pharmacology 70, no. 2 (August 2012): 251-258.  Full Text
    • Strickler, John H., and Herbert I. Hurwitz. “Maintenance therapy for first-line metastatic colorectal cancer: activity and sustainability..” The Oncologist 17, no. 1 (January 10, 2012): 9–10. https://doi.org/10.1634/theoncologist.2011-0358.
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    • Strickler, John H., and Herbert I. Hurwitz. “Bevacizumab-based therapies in the first-line treatment of metastatic colorectal cancer..” The Oncologist 17, no. 4 (January 2012): 513–24. https://doi.org/10.1634/theoncologist.2012-0003.
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    • Strickler, J. H., A. L. Cohn, C. Arrowood, S. Haley, M. Morse, H. Uronis, G. C. Blobe, S. D. Hsu, Y. Zafar, and H. Hurwitz. “Phase I study of dasatinib in combination with capecitabine, oxaliplatin, and bevacizumab followed by an expanded cohort in previously untreated metastatic colorectal cancer..” Journal of Clinical Oncology 29, no. 15_suppl (May 20, 2011): 3586–3586. https://doi.org/10.1200/jco.2011.29.15_suppl.3586.
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    • Strickler, J. H., A. L. Cohn, C. Arrowood, S. Haley, M. Morse, H. Uronis, G. C. Blobe, S. D. Hsu, Y. Zafar, and H. Hurwitz. “Phase I study of dasatinib in combination with capecitabine, oxaliplatin, and bevacizumab followed by an expanded cohort in previously untreated metastatic colorectal cancer..” Journal of Clinical Oncology : Official Journal of the American Society of Clinical Oncology 29, no. 15_suppl (May 2011).
    • Kline, Justin, Ian E. Brown, Yuan-Yuan Zha, Christian Blank, John Strickler, Harald Wouters, Long Zhang, and Thomas F. Gajewski. “Homeostatic proliferation plus regulatory T-cell depletion promotes potent rejection of B16 melanoma..” Clinical Cancer Research : An Official Journal of the American Association for Cancer Research 14, no. 10 (May 2008): 3156–67. https://doi.org/10.1158/1078-0432.ccr-07-4696.
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    • Coil, DA, Strickler, JH, Rai, SK, and Miller, AD. "Jaagsiekte Sheep Retrovirus Env Protein Stabilizes Retrovirus Vectors against Inactivation by Lung Surfactant, Centrifugation, and Freeze-Thaw Cycling." Journal of Virology 75, no. 18 (September 15, 2001): 8864-8867.  Full Text

  • Conference Papers

    • Turner, MC, Keenan, JE, Rushing, CN, Gulack, BC, Nussbaum, DP, Benrashid, E, Hyslop, T, Strickler, JH, Mantyh, CR, and Migaly, J. "Adjuvant Chemotherapy Improves Survival Following Resection of Locally Advanced Rectal Cancer with Pathologic Complete Response." January 11, 2019.  Full Text
    • Camidge, R, Heist, RS, Goldman, J, Angevin, E, Strickler, J, Morgensztern, D, Barve, M, Bauer, TM, Vokes, EE, Yi, T, Motwani, M, Parikh, A, Wu, J, and Kelly, K. "An open-label, multicenter, phase I study of ABBV-399 (telisotuzumab vedotin, teliso-V) as monotherapy (T) and in combination with erlotinib (T plus E) in non-small cell lung cancer (NSCLC)." 43rd ESMO Congress (ESMO). Munich, GERMANY. October 19, 2018 - October 23, 2018.: OXFORD UNIV PRESS, October 1, 2018.  Link to Item
    • Klempner, SJ, Bendell, J, Villaflor, VM, Tenner, L, Stein, S, Sirard, CA, Newman, W, Kagey, M, Schlienger, K, and Strickler, J. "Safety and efficacy of a DKK1 inhibitor (DKN-01) in combination with pembrolizumab (P) in patients (Pts) with advanced gastroesophageal (GE) malignancies." 43rd ESMO Congress (ESMO). Munich, GERMANY. October 19, 2018 - October 23, 2018.: OXFORD UNIV PRESS, October 1, 2018.  Link to Item
    • Bekaii-Saab, T, Marcello, K, Fisher, G, Kopetz, S, Strickler, J, Venook, A, and Obholz, K. "Variability of current global practice patterns in the management of metastatic colorectal cancer." ESMO 20th World Congress on Gastrointestinal Cancer. Barcelona, SPAIN. June 20, 2018 - June 23, 2018.: OXFORD UNIV PRESS, June 1, 2018.  Link to Item
    • Wainberg, Z, Strickler, J, Gordon, M, Barve, M, Wang, L, Yue, H, Motwani, M, Kasichayanula, S, Naumovski, L, and Hamilton, E. "Phase 1b open-label study evaluating the safety, pharmacokinetics, and preliminary efficacy of ABT-165 plus FOLFIRI in patients with second-line (2L) colorectal cancer (CRC)." ESMO 20th World Congress on Gastrointestinal Cancer. Barcelona, SPAIN. June 20, 2018 - June 23, 2018.: OXFORD UNIV PRESS, June 1, 2018.  Link to Item
    • Wainberg, Z, Wang, L, Yue, H, Motwani, M, Kasichayanula, S, Blaney, M, Naumovski, L, and Strickler, J. "ABT-165 plus FOLFIRI vs bevacizumab plus FOLFIRI in patients with metastatic colorectal cancer (mCRC) previously treated with fluoropyrimidine/oxaliplatin and bevacizumab - Trial in progress." ESMO 20th World Congress on Gastrointestinal Cancer. Barcelona, SPAIN. June 20, 2018 - June 23, 2018.: OXFORD UNIV PRESS, June 1, 2018.  Link to Item
    • Jia, J, Niedzwiecki, D, Uronis, HE, Morse, M, Zafar, Y, Hsu, SD, Bolch, E, Nagy, RJ, Lanman, RB, Talasaz, A, Haley, S, Nixon, AB, and Strickler, JH. "A phase I/II trial of cabozantinib (C) with or without panitumumab (P) in patients (pts) with RAS wild-type (WT) metastatic colorectal cancer (mCRC): Clinical outcomes in pts with MET amplification (amp) detected in blood." : American Society of Clinical Oncology (ASCO), May 20, 2018.  Full Text
    • Berlin, J, Ramanathan, RK, Strickler, JH, Subramaniam, DS, Marshall, J, Kang, Y-K, Hetman, R, Dudley, MW, Zeng, J, Nickner, C, Xiong, H, Komarnitsky, P, Shepherd, SP, Hurwitz, H, and Lenz, H-J. "A phase 1 dose-escalation study of veliparib with bimonthly FOLFIRI in patients with advanced solid tumours." April 2018.  Full Text
    • Loree, JM, Strickler, JH, Pereira, AAL, Lam, M, Raghav, KPS, Morris, VK, Menter, D, Banks, K, Nagy, RJ, Raymond, V, Overman, MJ, Talasaz, A, Lanman, RB, and Kopetz, S. "Serial monitoring of ctDNA to highlight mutation profiles in colorectal cancer." : American Society of Clinical Oncology (ASCO), February 2018.  Full Text
    • Theivanthiran, B, DeVito, NC, Evans, K, Zhao, F, Xiao, C, Goldschmidt, BS, Edgar, R, Holtzhausen, AH, Salama, AKS, Lewicki, J, Strickler, JH, Viator, JA, and Hanks, BA. "A HSP-TLR-Wnt5a paracrine signaling axis drives CXCR2 ligand recruitment of myeloid-derived suppressor cells and represents a novel adaptive resistance mechanism to anti-PD-1 antibody therapy." : BMC, November 7, 2017.  Link to Item
    • Goldman, J, Angevin, E, Strickler, J, Camidge, DR, Heist, R, Morgensztern, D, Barve, M, Yue, H, Beaulieu, J, Motwani, M, Afar, D, Naumovski, L, and Kelly, K. "MA 02.10 Phase I Study of ABBV-399 (Telisotuzumab Vedotin) as Monotherapy and in Combination with Erlotinib in NSCLC." : Elsevier BV, November 2017.  Full Text
    • Strickler, JH, Niedzwiecki, D, Zemla, T, Cercek, A, Fakih, M, Ng, K, Sanchez, FA, Wu, CS-Y, Peterson, S, Bandel, L, Grothey, A, and Bekaii-Saab, TS. "A phase II, open label study of tucatinib (ONT-380) combined with trastuzumab in patients with HER2+ metastatic colorectal cancer (mCRC)(MOUNTAINEER)." : American Society of Clinical Oncology (ASCO), May 20, 2017.  Full Text
    • Angevin, Eric, John Strickler, Colin Weekes, Rebecca Heist, Daniel Morgensztern, Xiaolin Fan, Ozzie Olyaie, et al. “First-In-Human Phase 1 Study of ABBV-399, an Antibody-Drug Conjugate (ADC) Targeting C-Met, in Patients with Non-Small Cell Lung Cancer (NSCLC).” In Journal of Thoracic Oncology, 12:S395–96. ELSEVIER SCIENCE INC, 2017.
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    • Bendell, J, Eckhardt, GS, Hochster, HS, Morris, VK, Strickler, J, Kapoun, AM, Wang, M, Xu, L, McGuire, K, Dupont, J, Faoro, L, and Munster, P. "Initial results from a phase 1a/b study of OMP-131R10, a first-in-class anti-RSPO3 antibody, in advanced solid tumors and previously treated metastatic colorectal cancer (CRC)." : Elsevier BV, December 2016.  Full Text
    • Angevin, E, Kelly, K, Heist, R, Morgensztern, D, Weekes, C, Bauer, TM, Ramanathan, RK, Nemunaitis, J, Fan, X, Olyaie, O, Parikh, A, Reilly, E, Afar, D, Naumovski, L, and Strickler, J. "First-in-human phase 1, dose-escalation and -expansion study of ABBV-399, an antibody-drug conjugate (ADC) targeting c-Met, in patients (pts) with advanced solid tumors." : Oxford University Press (OUP), October 2016.  Full Text
    • Ryan, D. P., J. Murphy, D. Mahalingam, J. Strickler, S. Stein, C. Sirard, S. Landau, and J. Bendell. “Current results of a phase I study of DKN-01 in combination with paclitaxel (P) in patients (pts) with advanced DKK1+esophageal cancer (EC) or gastro-esophageal junction tumors (GEJ).” In Annals of Oncology, 27:108–108. OXFORD UNIV PRESS, 2016.
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    • Clarke, JM, Blobe, GC, Strickler, JH, Uronis, HE, Zafar, Y, Morse, M, Dropkin, E, Howard, L, O'Neill, M, Rushing, CN, Niedzwiecki, D, Watson, H, Arrowood, C, and Hurwitz, H. "Phase Ib study of regorafenib (rego) and PF-03446962 (PF) in patients with refractory metastatic colorectal cancer (mCRC) (REGAL)." : American Society of Clinical Oncology (ASCO), May 20, 2016.  Full Text
    • Strickler, JH, Rushing, CN, Uronis, HE, Morse, M, Blobe, GC, Zafar, Y, Hsu, SD, Arrowood, C, Haley, S, Dropkin, E, Niedzwiecki, D, and Hurwitz, H. "Phase Ib study of cabozantinib plus panitumumab in KRAS wild-type (WT) metastatic colorectal cancer (mCRC)." : American Society of Clinical Oncology (ASCO), May 20, 2016.  Full Text
    • Strickler, JH, Rangwala, FA, Rushing, C, Niedzwiecki, D, Altomare, I, Uronis, HE, Hsu, SD, Zafar, Y, Morse, M, Chang, DZ, Wells, JL, Blackwell, KL, Marcom, PK, Webb, AR, Dropkin, E, Arrowood, C, and Hurwitz, H. "X-TRAP: Phase I/II study of capecitabine (X) plus ziv-aflibercept (TRAP) in metastatic colorectal cancer (mCRC)." : American Society of Clinical Oncology (ASCO), February 2016.  Full Text
    • Zhang, Tian, Rengasamy Boominathan, Brad Foulk, Mark Carle Connelly, Chandra Rao, Gabor Kemeny, John H. Strickler, et al. “Evaluation of a novel c-MET based circulating tumor cell (CTC) biomarker in patients with gastrointestinal (GI) and genitourinary (GU) malignancies..” In Journal of Clinical Oncology, Vol. 33. AMER SOC CLINICAL ONCOLOGY, 2015.
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    • Kang, Y-K, LoRusso, P, Salgia, R, Yen, C-J, Lin, C-C, Ramanathan, RK, Kaminker, P, Sokolova, I, Bhathena, A, Wang, L, Naumovski, L, and Strickler, JH. "Phase I study of ABT-700, an anti-c-Met antibody, in patients (pts) with advanced gastric or esophageal cancer (GEC)." : American Society of Clinical Oncology (ASCO), January 20, 2015.  Full Text
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