Skip to main content

John S Yi

Adjunct Assistant Professor in the Department of Surgery
Surgery, Surgical Sciences
915 S. LaSalle Street, 204 SORF (Bldg. 41) Box 2926, Durham, NC 27710

Overview


I am an immunologist, with a focus to characterize the immune system in response to infectious and non-infectious diseases including cancer, HIV, autoimmune disease, and transplantation. My goals are to identify novel biomarkers/immune signatures that clinicians can utilize to diagnosis, predict disease outcomes, and determine patients' response to treatment.

Current Appointments & Affiliations


Adjunct Assistant Professor in the Department of Surgery · 2021 - Present Surgery, Surgical Sciences, Surgery

Recent Publications


Mode of injury and level of synovitis alter inflammatory chondrocyte gene expression and associated pathways.

Journal Article Sci Rep · November 21, 2024 Although various joint injuries result in post-traumatic osteoarthritis (PTOA), differences in chondrocyte response to specific injuries, such as blunt compression or fracture, are unclear. Furthermore, the role of underlying joint inflammation, or synovit ... Full text Link to item Cite

Differences in microenvironment of lung cancer and pleural effusions by single-cell RNA sequencing.

Journal Article Lung Cancer · July 2024 BACKGROUND: Direct comparison of tumor microenvironment of matched lung cancer biopsies and pleural effusions (PE) from the same patients is critical in understanding tumor biology but has not been performed. This is the first study to compare the lung can ... Full text Link to item Cite

Immune dysregulation in chronic inflammatory demyelinating polyneuropathy.

Journal Article J Neuroimmunol · June 15, 2024 OBJECTIVE: Chronic inflammatory demyelinating polyneuropathy (CIDP) is an autoimmune disorder of the peripheral nerves with an incompletely understood underlying pathophysiology. This investigation focused on defining B and T cell frequencies, T cell funct ... Full text Link to item Cite
View All Publications

Recent Grants


Defining the clinical phenotype and immunopathology of seronegative MG

ResearchCo Investigator · Awarded by Myasthenia Gravis Foundation · 2021 - 2023

VTEU Task D Option 2 Protocol FY.2015.A4D14.0033

ResearchInvestigator · Awarded by National Institutes of Health · 2015 - 2022

Biomarkers predicting response to eculizumab in MG (NonFed)

ResearchMentor · Awarded by The George Washington University · 2021 - 2022

View All Grants

Education, Training & Certifications


University of Alabama, Birmingham · 2010 Ph.D.