Scholars@Duke
Joseph Geradts

Joseph Geradts

Adjunct Professor in the Department of Pathology
Pathology
joseph.geradts@duke.edu
Duke Box 3712, Durham, NC 27710
Rm 3108 Meyer Ward, Department of Pathology, Durham, NC 27710

Overview

Dr. Geradts' primary research focus is on the molecular pathology of breast cancer. His laboratory uses genomic profiling strategies to identify novel candidate breast cancer genes. Dr. Geradts is also interested in biomarker development. He directs the Tissue Core of Duke's Breast Cancer SPORE and collaborates on numerous breast cancer related research projects with other investigators at Duke and elsewhere.

Current Appointments & Affiliations

Adjunct Professor in the Department of Pathology · 2015 - Present Pathology, Clinical Science Departments

In the News

Published December 2, 2013
Duke study: Many breast cancers may be linked with cholesterol byproduct

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Recent Publications

TBCRC 035: randomized phase II pharmacodynamic study of standard and reduced-dose palbociclib with endocrine therapy in hormone receptor (HR)-positive previously treated metastatic breast cancer.

Journal Article ESMO Open · March 10, 2026 BACKGROUND: The cyclin-dependent kinase 4/6 inhibitor palbociclib induces neutropenia, resulting in dose delays and reductions. PATIENTS AND METHODS: This multicenter phase II trial randomly assigned patients with metastatic hormone receptor-positive, huma ... Full text Link to item Cite

Genetic Profiling of Mammary Periductal Stromal Tumors With Histologic Correlation Highlights High-Grade and Low-Grade Groups and Similarities to Phyllodes Tumors.

Journal Article Mod Pathol · March 2026 Periductal stromal tumors (PDST) of the breast are rare biphasic neoplasms with morphologic similarities to phyllodes tumors (PTs). The histologic spectrum of PDST is broad but has not been well characterized, and its genetic underpinnings remain unknown. ... Full text Link to item Cite

Patch Based Analysis with Machine Learning to Aid Breast Cancer Recurrence Prediction

Conference Communications in Computer and Information Science · January 1, 2026 Since the introduction of whole slide scanners, machine learning research has become a popular area of interest in digital pathology. Many studies have attempted to use machine learning to aid pathology tasks such as breast cancer diagnosis and metastasis ... Full text Cite
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Recent Grants

Developing a HER3 Vaccine to Prevent Resistance to Endocrine Therapy

ResearchCollaborator · Awarded by Department of Defense · 2012 - 2022

A Molecular Framework for Understanding DCIS

ResearchCo Investigator · Awarded by Department of Defense · 2014 - 2022

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Education

The University of Chicago · 1987 M.D.
University of California, Berkeley · 1984 M.A.