Overview
Current Appointments & Affiliations
Adjunct Professor in the Department of Pathology
·
2015 - Present
Pathology,
Clinical Science Departments
Recent Publications
Comparative study of intra- and inter-observer variability in manual scoring of HER2 immunohistochemical stains on glass slides versus paired digital images with emphasis on the low end of the expression spectrum.
Journal Article Hum Pathol · June 25, 2025 With the advent of new therapeutic agents showing efficacy in human breast cancers with low levels of the HER2 oncoprotein, it has become important for pathologists to accurately categorize HER2 expression at the low end of the spectrum. At the same time, ... Full text Link to item CiteComputational Pathology Detection of Hypoxia-Induced Morphologic Changes in Breast Cancer.
Journal Article Am J Pathol · April 2025 Understanding the tumor hypoxic microenvironment is crucial for grasping tumor biology, clinical progression, and treatment responses. This study presents a novel application of artificial intelligence in computational histopathology to evaluate hypoxia in ... Full text Link to item CiteXIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant.
Journal Article Transl Oncol · May 2024 OBJECTIVE: To assess the expression pattern of X-linked inhibitor of apoptosis protein (XIAP), a cellular stress sensor, and delineate the associated changes in the tumor immune microenvironment (TiME) for prognostic value and new therapeutic targets in in ... Full text Link to item CiteRecent Grants
Developing a HER3 Vaccine to Prevent Resistance to Endocrine Therapy
ResearchCollaborator · Awarded by Department of Defense · 2012 - 2022Detection and Elimination of Oncogenic Signaling Networks in Pre-malignant and Malignant Cells with Magnetic Resonance Imaging
ResearchCo Investigator · Awarded by Department of Defense · 2012 - 2022A Molecular Framework for Understanding DCIS
ResearchCo Investigator · Awarded by Department of Defense · 2014 - 2022View All Grants
Education, Training & Certifications
The University of Chicago ·
1987
M.D.
University of California, Berkeley ·
1984
M.A.