Scholars@Duke

• Background
• 

  Education, Training, & Certifications

  • Attending Pathologist, Pathology, State University of New York - Buffalo 2001 - 2005
  • Attending Surgical Pathologist, Pathology, University of North Carolina - Chapel Hill 1992 - 1993
  • Fellowship/Research, National Cancer Institute, National Institutes of Health 1990 - 1991
  • Fellow, Pathology, Stanford University 1989 - 1990
  • Resident, Pathology, University of California San Francisco, School of Medicine 1987 - 1989
  • M.D., The University of Chicago 1987
  • M.A., University of California - Berkeley 1984
• 

  Previous Appointments & Affiliations

  • Member of the Duke Cancer Institute, Duke Cancer Institute, Institutes and Centers 2005 - 2015
  • Professor of Pathology, Pathology, Clinical Science Departments 2006 - 2014
  • Instructor, Temporary in the Department of Pathology, Pathology, Clinical Science Departments 2005
• Recognition
• 

  In the News

  • DEC 2, 2013

    The News & Observer

    Duke study: Many breast cancers may be linked with cholesterol byproduct
• Expertise
• 

  Global Scholarship

  • Research

    • Belarus (Country) 
• Research
• 

  Selected Grants

  • Molecular Determinants of Health Disparities in Inflammatory Breast Cancer awarded by National Institutes of Health 2021 - 2026
  • Detection and Elimination of Oncogenic Signaling Networks in Pre-malignant and Malignant Cells with Magnetic Resonance Imaging awarded by Department of Defense 2012 - 2022
  • Developing a HER3 Vaccine to Prevent Resistance to Endocrine Therapy awarded by Department of Defense 2012 - 2022
  • A Molecular Framework for Understanding DCIS awarded by Department of Defense 2014 - 2022
  • Genomic Diversity and the Microenvironment as Drivers of Progression in DCIS awarded by Department of Defense 2014 - 2021
  • CaMKK2: a druggable target that regulates macrophage function in breast cancer awarded by Susan G. Komen Breast Cancer Foundation 2013 - 2017
  • Targeting nuclear FGF receptor to improve chemotherapy response in triple-negative breast cancer awarded by Department of Defense 2013 - 2016
  • Atlantic Breast and Gynecologic Clinical Validation Center awarded by National Institutes of Health 1999 - 2016
  • KCNK9 Imprinting in Breast Cancer Progression and Metastasis awarded by National Institutes of Health 2011 - 2015
  • Heat and Radiation Effects on Tumor Microcirculation awarded by National Institutes of Health 1985 - 2015
  • Harnessing the power of light to see and treat breast cancer awarded by United States Army Medical Research and Materiel Command 2009 - 2015
  • TCGA - Breast Cancer Tissue Acquisition awarded by National Institutes of Health 2010 - 2015
  • A Fluorescence Histology System for In Vivo Breast Tumor Margin Assessment awarded by National Institutes of Health 2011 - 2013
  • Nuclear Snail-1 in the progression of Estrogen Receptor(-) invasive breast cancer awarded by National Institutes of Health 2011 - 2013
  • Can Optical Spectroscopy Predict Early Treatment Response in Solid Tumors awarded by National Institutes of Health 2010 - 2012
  • Somatic Genetic Changes in Early Breast Cancer awarded by National Institutes of Health 2005 - 2007
• 

  External Relationships

  • I am employed by East Carolina University.
• Publications & Artistic Works
• 

  Selected Publications

  • Academic Articles

    • Hurson, Amber N., Alina M. Hamilton, Linnea T. Olsson, Erin L. Kirk, Mark E. Sherman, Benjamin C. Calhoun, Joseph Geradts, and Melissa A. Troester. “Reproducibility and intratumoral heterogeneity of the PAM50 breast cancer assay.” Breast Cancer Research and Treatment 199, no. 1 (May 2023): 147–54. https://doi.org/10.1007/s10549-023-06888-1.
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    • Johnson, Helen M., Anas Mohamed, Muhammad M. Hassan, Joseph Geradts, Lauren Geisel, Nasreen A. Vohra, and Jan H. Wong. “Race-Related Differences in the Clinical Presentation and Histopathologic Features of Phyllodes Tumor.” The American Surgeon 89, no. 3 (March 2023): 407–13. https://doi.org/10.1177/00031348211029841.
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    • Hiroto, Alex, Won Kyung Kim, Ariana Pineda, Yongfeng He, Dong-Hoon Lee, Vien Le, Adam W. Olson, et al. “Stromal androgen signaling acts as tumor niches to drive prostatic basal epithelial progenitor-initiated oncogenesis.” Nat Commun 13, no. 1 (November 2, 2022): 6552. https://doi.org/10.1038/s41467-022-34282-w.
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    • Rebbeck, Clare A., Jian Xian, Susanne Bornelöv, Joseph Geradts, Amy Hobeika, Heather Geiger, Jose Franco Alvarez, et al. “Gene expression signatures of individual ductal carcinoma in situ lesions identify processes and biomarkers associated with progression towards invasive ductal carcinoma.” Nat Commun 13, no. 1 (June 13, 2022): 3399. https://doi.org/10.1038/s41467-022-30573-4.
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    • Cao, X., J. Geradts, M. W. Dewhirst, and H. -. W. Lo. “Correction: Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.” Oncogene 41, no. 8 (February 2022): 1225–26. https://doi.org/10.1038/s41388-021-02043-6.
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    • Carmichael, Iain, Benjamin C. Calhoun, Katherine A. Hoadley, Melissa A. Troester, Joseph Geradts, Heather D. Couture, Linnea Olsson, et al. “JOINT AND INDIVIDUAL ANALYSIS OF BREAST CANCER HISTOLOGIC IMAGES AND GENOMIC COVARIATES.” Ann Appl Stat 15, no. 4 (December 2021): 1697–1722. https://doi.org/10.1214/20-aoas1433.
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    • Devi, Gayathri R., Pascal Finetti, Michael A. Morse, Seayoung Lee, Alexandre de Nonneville, Steven Van Laere, Jesse Troy, Joseph Geradts, Shannon McCall, and Francois Bertucci. “Expression of X-Linked Inhibitor of Apoptosis Protein (XIAP) in Breast Cancer Is Associated with Shorter Survival and Resistance to Chemotherapy.” Cancers (Basel) 13, no. 11 (June 4, 2021). https://doi.org/10.3390/cancers13112807.
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    • Frankhauser, David E., Tijana Jovanovic-Talisman, Lily Lai, Lisa D. Yee, Lihong V. Wang, Ashish Mahabal, Joseph Geradts, et al. “Spatiotemporal strategies to identify aggressive biology in precancerous breast biopsies.” Wires Mech Dis 13, no. 2 (March 2021): e1506. https://doi.org/10.1002/wsbm.1506.
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    • Benefield, Halei C., Katherine E. Reeder-Hayes, Hazel B. Nichols, Benjamin C. Calhoun, Michael I. Love, Erin L. Kirk, Joseph Geradts, et al. “Outcomes of Hormone-Receptor Positive, HER2-Negative Breast Cancers by Race and Tumor Biological Features.” Jnci Cancer Spectr 5, no. 1 (February 2021). https://doi.org/10.1093/jncics/pkaa072.
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    • Nichols, Brandon S., Erika Chelales, Roujia Wang, Amanda Schulman, Jennifer Gallagher, Rachel A. Greenup, Joseph Geradts, et al. “Quantitative assessment of distant recurrence risk in early stage breast cancer using a nonlinear combination of pathological, clinical and imaging variables.” J Biophotonics 13, no. 10 (October 2020): e201960235. https://doi.org/10.1002/jbio.201960235.
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    • Benefield, Halei C., Emma H. Allott, Katherine E. Reeder-Hayes, Charles M. Perou, Lisa A. Carey, Joseph Geradts, Xuezheng Sun, Benjamin C. Calhoun, and Melissa A. Troester. “Borderline Estrogen Receptor-Positive Breast Cancers in Black and White Women.” J Natl Cancer Inst 112, no. 7 (July 1, 2020): 728–36. https://doi.org/10.1093/jnci/djz206.
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    • Waks, A. G., O. Cohen, B. Kochupurakkal, D. Kim, C. E. Dunn, J. Buendia Buendia, S. Wander, et al. “Reversion and non-reversion mechanisms of resistance to PARP inhibitor or platinum chemotherapy in BRCA1/2-mutant metastatic breast cancer.” Ann Oncol 31, no. 5 (May 2020): 590–98. https://doi.org/10.1016/j.annonc.2020.02.008.
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    • He, Yongfeng, Jiaqi Mi, Adam Olson, Joseph Aldahl, Erika Hooker, Eun-Jeong Yu, Vien Le, et al. “Androgen receptor with short polyglutamine tract preferably enhances Wnt/β-catenin-mediated prostatic tumorigenesis.” Oncogene 39, no. 16 (April 2020): 3276–91. https://doi.org/10.1038/s41388-020-1214-7.
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    • Aldahl, Joseph, Jiaqi Mi, Ariana Pineda, Won Kyung Kim, Adam Olson, Erika Hooker, Yongfeng He, et al. “Aberrant activation of hepatocyte growth factor/MET signaling promotes β-catenin-mediated prostatic tumorigenesis.” J Biol Chem 295, no. 2 (January 10, 2020): 631–44. https://doi.org/10.1074/jbc.RA119.011137.
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    • Allott, Emma H., Yue Shan, Mengjie Chen, Xuezheng Sun, Susana Garcia-Recio, Erin L. Kirk, Andrew F. Olshan, et al. “Bimodal age distribution at diagnosis in breast cancer persists across molecular and genomic classifications.” Breast Cancer Res Treat 179, no. 1 (January 2020): 185–95. https://doi.org/10.1007/s10549-019-05442-2.
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    • Fackler, Mary Jo, Soonweng Cho, Leslie Cope, Edward Gabrielson, Kala Visvanathan, Kathleen Wilsbach, Danielle Meir-Levi, et al. “DNA methylation markers predict recurrence-free interval in triple-negative breast cancer.” Npj Breast Cancer 6 (2020): 3. https://doi.org/10.1038/s41523-020-0145-3.
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    • Le, Vien, Yongfeng He, Joseph Aldahl, Erika Hooker, Eun-Jeong Yu, Adam Olson, Won Kyung Kim, et al. “Loss of androgen signaling in mesenchymal sonic hedgehog responsive cells diminishes prostate development, growth, and regeneration.” Plos Genet 16, no. 1 (January 2020): e1008588. https://doi.org/10.1371/journal.pgen.1008588.
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    • Olson, Adam, Vien Le, Joseph Aldahl, Eun-Jeong Yu, Erika Hooker, Yongfeng He, Dong-Hong Lee, et al. “The comprehensive role of E-cadherin in maintaining prostatic epithelial integrity during oncogenic transformation and tumor progression.” Plos Genet 15, no. 10 (October 2019): e1008451. https://doi.org/10.1371/journal.pgen.1008451.
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    • He, Yongfeng, Daniel T. Johnson, Julie S. Yang, Huiqing Wu, Sungyong You, Junhee Yoon, Dong-Hoon Lee, et al. “Loss of the tumor suppressor, Tp53, enhances the androgen receptor-mediated oncogenic transformation and tumor development in the mouse prostate.” Oncogene 38, no. 38 (September 2019): 6507–20. https://doi.org/10.1038/s41388-019-0901-8.
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    • Tossas-Milligan, Katherine, Sundus Shalabi, Veronica Jones, Patricia J. Keely, Matthew W. Conklin, Kevin W. Eliceiri, Robert Winn, et al. “Mammographic density: intersection of advocacy, science, and clinical practice.” Curr Breast Cancer Rep 11, no. 3 (September 2019): 100–110. https://doi.org/10.1007/s12609-019-00316-4.
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    • Jiang, Liejun, Xiliu Zhang, Joseph Geradts, Qiang Wei, Steven Hochwald, Hui Xu, and Huayi Huang. “Expression of tetraspanins NET-6 and CD151 in breast cancer as a potential tumor biomarker.” Clin Exp Med 19, no. 3 (August 2019): 377–84. https://doi.org/10.1007/s10238-019-00554-x.
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    • Racioppi, Luigi, Erik R. Nelson, Wei Huang, Debarati Mukherjee, Scott A. Lawrence, William Lento, Anna Maria Masci, et al. “CaMKK2 in myeloid cells is a key regulator of the immune-suppressive microenvironment in breast cancer.” Nature Communications 10, no. 1 (June 2019): 2450. https://doi.org/10.1038/s41467-019-10424-5.
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    • Lee, Dong-Hong, Eun-Jeong Yu, Joseph Aldahl, Julie Yang, Yongfeng He, Erika Hooker, Vien Le, et al. “Deletion of the p16INK4a tumor suppressor and expression of the androgen receptor induce sarcomatoid carcinomas with signet ring cells in the mouse prostate.” Plos One 14, no. 1 (2019): e0211153. https://doi.org/10.1371/journal.pone.0211153.
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    • Williams, Lindsay A., Katherine A. Hoadley, Hazel B. Nichols, Joseph Geradts, Charles M. Perou, Michael I. Love, Andrew F. Olshan, and Melissa A. Troester. “Differences in race, molecular and tumor characteristics among women diagnosed with invasive ductal and lobular breast carcinomas.” Cancer Causes Control 30, no. 1 (January 2019): 31–39. https://doi.org/10.1007/s10552-018-1121-1.
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    • Paoletti, Costanza, Gaia Schiavon, Emily M. Dolce, Elizabeth P. Darga, T Hedley Carr, Joseph Geradts, Matthias Hoch, et al. “Circulating Biomarkers and Resistance to Endocrine Therapy in Metastatic Breast Cancers: Correlative Results from AZD9496 Oral SERD Phase I Trial.” Clin Cancer Res 24, no. 23 (December 1, 2018): 5860–72. https://doi.org/10.1158/1078-0432.CCR-18-1569.
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    • Jiang, Liejun, Xiliu Zhang, Chenglin Xiang, Joseph Geradts, Qiang Wei, Yuanzi Liang, Huayi Huang, and Jun-Fa Xu. “Differential cellular localization of CELSR2 and ING4 and correlations with hormone receptor status in breast cancer.” Histol Histopathol 33, no. 8 (August 2018): 835–42. https://doi.org/10.14670/HH-11-979.
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    • Xiao, Tengfei, Wei Li, Xiaoqing Wang, Han Xu, Jixin Yang, Qiu Wu, Ying Huang, et al. “Estrogen-regulated feedback loop limits the efficacy of estrogen receptor-targeted breast cancer therapy.” Proc Natl Acad Sci U S A 115, no. 31 (July 31, 2018): 7869–78. https://doi.org/10.1073/pnas.1722617115.
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    • Evans, Myron K., Michael C. Brown, Joseph Geradts, Xuhui Bao, Timothy J. Robinson, Mohit Kumar Jolly, Peter B. Vermeulen, et al. “XIAP Regulation by MNK Links MAPK and NFκB Signaling to Determine an Aggressive Breast Cancer Phenotype.” Cancer Res 78, no. 7 (April 1, 2018): 1726–38. https://doi.org/10.1158/0008-5472.CAN-17-1667.
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    • Allott, Emma H., Joseph Geradts, Stephanie M. Cohen, Thaer Khoury, Gary R. Zirpoli, Wiam Bshara, Warren Davis, et al. “Frequency of breast cancer subtypes among African American women in the AMBER consortium.” Breast Cancer Res 20, no. 1 (February 6, 2018): 12. https://doi.org/10.1186/s13058-018-0939-5.
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    • Troester, Melissa A., Xuezheng Sun, Emma H. Allott, Joseph Geradts, Stephanie M. Cohen, Chiu-Kit Tse, Erin L. Kirk, et al. “Racial Differences in PAM50 Subtypes in the Carolina Breast Cancer Study.” J Natl Cancer Inst 110, no. 2 (February 1, 2018): 176–82. https://doi.org/10.1093/jnci/djx135.
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    • Williams, Lindsay A., Hazel B. Nichols, Katherine A. Hoadley, Chiu Kit Tse, Joseph Geradts, Mary Elizabeth Bell, Charles M. Perou, Michael I. Love, Andrew F. Olshan, and Melissa A. Troester. “Reproductive risk factor associations with lobular and ductal carcinoma in the Carolina Breast Cancer Study.” Cancer Causes Control 29, no. 1 (January 2018): 25–32. https://doi.org/10.1007/s10552-017-0977-9.
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    • Butler, Eboneé N., Jeannette T. Bensen, Mengjie Chen, Kathleen Conway, David B. Richardson, Xuezheng Sun, Joseph Geradts, Andrew F. Olshan, and Melissa A. Troester. “Prediagnostic Smoking Is Associated with Binary and Quantitative Measures of ER Protein and ESR1 mRNA Expression in Breast Tumors.” Cancer Epidemiol Biomarkers Prev 27, no. 1 (January 2018): 67–74. https://doi.org/10.1158/1055-9965.EPI-17-0404.
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    • Couture, Heather D., Lindsay A. Williams, Joseph Geradts, Sarah J. Nyante, Ebonee N. Butler, J. S. Marron, Charles M. Perou, Melissa A. Troester, and Marc Niethammer. “Image analysis with deep learning to predict breast cancer grade, ER status, histologic subtype, and intrinsic subtype.” Npj Breast Cancer 4 (2018): 30. https://doi.org/10.1038/s41523-018-0079-1.
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    • Williams, Lindsay A., Ebonee N. Butler, Xuezheng Sun, Emma H. Allott, Stephanie M. Cohen, Ashley M. Fuller, Katherine A. Hoadley, et al. “TP53 protein levels, RNA-based pathway assessment, and race among invasive breast cancer cases.” Npj Breast Cancer 4 (2018): 13. https://doi.org/10.1038/s41523-018-0067-5.
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    • Khoury, Thaer, Gary Zirpoli, Stephanie M. Cohen, Joseph Geradts, Angela Omilian, Warren Davis, Wiam Bshara, et al. “Ki-67 Expression in Breast Cancer Tissue Microarrays: Assessing Tumor Heterogeneity, Concordance With Full Section, and Scoring Methods.” Am J Clin Pathol 148, no. 2 (August 1, 2017): 108–18. https://doi.org/10.1093/ajcp/aqx053.
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    • Sood, Ashwani K., Joseph Geradts, and Jessica Young. “Prostate-derived Ets factor, an oncogenic driver in breast cancer.” Tumour Biol 39, no. 5 (May 2017): 1010428317691688. https://doi.org/10.1177/1010428317691688.
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    • Alfaqih, Mahmoud A., Erik R. Nelson, Wen Liu, Rachid Safi, Jeffery S. Jasper, Everardo Macias, Joseph Geradts, et al. “CYP27A1 Loss Dysregulates Cholesterol Homeostasis in Prostate Cancer.” Cancer Res 77, no. 7 (April 1, 2017): 1662–73. https://doi.org/10.1158/0008-5472.CAN-16-2738.
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    • Nichols, Brandon S., Antonio Llopis, Gregory M. Palmer, Samuel S. McCachren, Ozlem Senlik, David Miller, Martin A. Brooke, et al. “Miniature spectral imaging device for wide-field quantitative functional imaging of the morphological landscape of breast tumor margins.” J Biomed Opt 22, no. 2 (February 1, 2017): 26007. https://doi.org/10.1117/1.JBO.22.2.026007.
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    • Mueller, Jenna L., Jennifer E. Gallagher, Rhea Chitalia, Marlee Krieger, Alaattin Erkanli, Rebecca M. Willett, Joseph Geradts, and Nimmi Ramanujam. “Rapid staining and imaging of subnuclear features to differentiate between malignant and benign breast tissues at a point-of-care setting.” J Cancer Res Clin Oncol 142, no. 7 (July 2016): 1475–86. https://doi.org/10.1007/s00432-016-2165-9.
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    • Taylor, Nicholas J., Nana Nikolaishvili-Feinberg, Bentley R. Midkiff, Kathleen Conway, Robert C. Millikan, and Joseph Geradts. “Rational Manual and Automated Scoring Thresholds for the Immunohistochemical Detection of TP53 Missense Mutations in Human Breast Carcinomas.” Appl Immunohistochem Mol Morphol 24, no. 6 (July 2016): 398–404. https://doi.org/10.1097/PAI.0000000000000207.
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    • Allott, Emma H., Joseph Geradts, Xuezheng Sun, Stephanie M. Cohen, Gary R. Zirpoli, Thaer Khoury, Wiam Bshara, et al. “Intratumoral heterogeneity as a source of discordance in breast cancer biomarker classification.” Breast Cancer Res 18, no. 1 (June 28, 2016): 68. https://doi.org/10.1186/s13058-016-0725-1.
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    • Kennedy, Stephanie, Matthew Caldwell, Torre Bydlon, Christine Mulvey, Jenna Mueller, Lee Wilke, William Barry, Nimmi Ramanujam, and Joseph Geradts. “Correlation of breast tissue histology and optical signatures to improve margin assessment techniques.” J Biomed Opt 21, no. 6 (June 1, 2016): 66014. https://doi.org/10.1117/1.JBO.21.6.066014.
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    • Geradts, Joseph, Jeffrey Groth, Yuan Wu, and Genglin Jin. “Validation of an oligo-gene signature for the prognostic stratification of ductal carcinoma in situ (DCIS).” Breast Cancer Res Treat 157, no. 3 (June 2016): 447–59. https://doi.org/10.1007/s10549-016-3838-4.
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    • Yeh, T., V. Jacobs, H. Angell, J. Geradts, J. Hou, J. Karakunnel, and C. Barrett. “60PD Inhibition of pEGFR in paired tumour biopsies from TKI treatment-naïve EGFR mutant NSCLC patients treated with gefitinib (EGFR inhibitor) or gefitinib in combination with durvalumab (anti-PD-L1).” J Thorac Oncol 11, no. 4 Suppl (April 2016): S80–81. https://doi.org/10.1016/S1556-0864(16)30173-3.
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    • Allott, Emma H., Stephanie M. Cohen, Joseph Geradts, Xuezheng Sun, Thaer Khoury, Wiam Bshara, Gary R. Zirpoli, et al. “Performance of Three-Biomarker Immunohistochemistry for Intrinsic Breast Cancer Subtyping in the AMBER Consortium.” Cancer Epidemiol Biomarkers Prev 25, no. 3 (March 2016): 470–78. https://doi.org/10.1158/1055-9965.EPI-15-0874.
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    • Canfield, Kaleigh, Wendy Wells, Joseph Geradts, William B. Kinlaw, Chao Cheng, and Manabu Kurokawa. “Inverse association between MDM2 and HUWE1 protein expression levels in human breast cancer and liposarcoma.” Int J Clin Exp Pathol 9, no. 6 (2016): 6342–49.
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    • Mueller, Jenna L., Henry L. Fu, Jeffrey K. Mito, Melodi J. Whitley, Rhea Chitalia, Alaattin Erkanli, Leslie Dodd, et al. “A quantitative microscopic approach to predict local recurrence based on in vivo intraoperative imaging of sarcoma tumor margins.” Int J Cancer 137, no. 10 (November 15, 2015): 2403–12. https://doi.org/10.1002/ijc.29611.
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    • Horton, Janet K., Sharareh Siamakpour-Reihani, Chen-Ting Lee, Ying Zhou, Wei Chen, Joseph Geradts, Diane R. Fels, et al. “FAS Death Receptor: A Breast Cancer Subtype-Specific Radiation Response Biomarker and Potential Therapeutic Target.” Radiat Res 184, no. 5 (November 2015): 456–69. https://doi.org/10.1667/RR14089.1.
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    • Thress, Kenneth, James Leeson, Joseph Geradts, Martin Schuler, Myung-Ju Ahn, Juergen Wolf, Kathryn A. Gold, et al. “Design, Execution, and Preliminary Biomarker Results from Paired Tumor Biopsy Cohorts of the AZD9291 AURA Trial.” Journal of Thoracic Oncology 10, no. 9 (September 1, 2015): S320–S320.
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    • Sutton, Linda M., Joseph Geradts, Erika P. Hamilton, Kathleen A. Havlin, Gretchen G. Kimmick, P Kelly Marcom, Neil L. Spector, et al. “CHAMBER: A Regional Performance Improvement CME Initiative for Breast Cancer Health Care Providers.” J Natl Compr Canc Netw 13, no. 8 (August 2015): 1005–11. https://doi.org/10.6004/jnccn.2015.0121.
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    • Horton, Janet K., Rachel C. Blitzblau, Sua Yoo, Joseph Geradts, Zheng Chang, Jay A. Baker, Gregory S. Georgiade, et al. “Preoperative Single-Fraction Partial Breast Radiation Therapy: A Novel Phase 1, Dose-Escalation Protocol With Radiation Response Biomarkers.” Int J Radiat Oncol Biol Phys 92, no. 4 (July 15, 2015): 846–55. https://doi.org/10.1016/j.ijrobp.2015.03.007.
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    • Li, Shenduo, Sturgis Payne, Fang Wang, Peter Claus, Zuowei Su, Jeffrey Groth, Joseph Geradts, et al. “Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance.” Breast Cancer Res 17, no. 1 (July 4, 2015): 91. https://doi.org/10.1186/s13058-015-0590-3.
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    • Li, S., S. Payne, F. Wang, P. Claus, Z. Su, J. Groth, J. Geradts, et al. “Nuclear basic fibroblast growth factor regulates triple-negative breast cancer chemo-resistance.” Breast Cancer Research, 2015. https://doi.org/10.1186/s13058-015-0590-3.
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    • Nichols, Brandon S., Christine E. Schindler, Jonathon Q. Brown, Lee G. Wilke, Christine S. Mulvey, Marlee S. Krieger, Jennifer Gallagher, et al. “A Quantitative Diffuse Reflectance Imaging (QDRI) System for Comprehensive Surveillance of the Morphological Landscape in Breast Tumor Margins.” Plos One 10, no. 6 (2015): e0127525. https://doi.org/10.1371/journal.pone.0127525.
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    • Drendall, Catherine Ibarra, William Barry, Corinne Ramos, Nora Tolbert, Joseph Geradts, Emanuel Petricoin, and Victoria Seewaldt. “Abstract C16: Feasibility study: Protein profiling of primary breast cancers from premenopausal women.” Cancer Epidemiology, Biomarkers &Amp; Prevention 23, no. 11_Supplement (November 1, 2014): C16–C16. https://doi.org/10.1158/1538-7755.disp13-c16.
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    • Conway, Kathleen, Sharon N. Edmiston, Ryan May, Pei Fen Kuan, Haitao Chu, Christopher Bryant, Chiu-Kit Tse, et al. “DNA methylation profiling in the Carolina Breast Cancer Study defines cancer subclasses differing in clinicopathologic characteristics and survival.” Breast Cancer Res 16, no. 5 (October 7, 2014): 450. https://doi.org/10.1186/s13058-014-0450-6.
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    • Horton, Janet K., Mark W. Dewhirst, Sharareh Siamakpour-Reihani, Yingchun Zhou, Joseph Geradts, Jen-Tsan Ashley Chi, and Wei Chen. “Changes in Gene Expression After Radiation in Human Breast Cancers: A Guide to Predicting and Modulating Radiation Response.” Journal of Womens Health 23, no. 10 (October 1, 2014): 861–861.
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    • Cheng, Qing, Jeffrey T. Chang, William R. Gwin, Jun Zhu, Stefan Ambs, Joseph Geradts, and H Kim Lyerly. “A signature of epithelial-mesenchymal plasticity and stromal activation in primary tumor modulates late recurrence in breast cancer independent of disease subtype.” Breast Cancer Res 16, no. 4 (July 25, 2014): 407. https://doi.org/10.1186/s13058-014-0407-9.
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    • Henao, Ricardo, Joseph Geradts, Manabu Kurokawa, Sally Kornbluth, and Joseph E. Lucas. “Automated, quantitative analysis of histopathological staining in nuclei.” Amia Jt Summits Transl Sci Proc 2014 (2014): 54–59.
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    • Malin, Dmitry, Elena Strekalova, Vladimir Petrovic, Allison M. Deal, Abraham Al Ahmad, Barbara Adamo, C Ryan Miller, et al. “αB-crystallin: a novel regulator of breast cancer metastasis to the brain.” Clin Cancer Res 20, no. 1 (January 1, 2014): 56–67. https://doi.org/10.1158/1078-0432.CCR-13-1255.
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    • Nelson, Erik R., Suzanne E. Wardell, Jeff S. Jasper, Sunghee Park, Sunil Suchindran, Matthew K. Howe, Nicole J. Carver, et al. “27-Hydroxycholesterol links hypercholesterolemia and breast cancer pathophysiology.” Science 342, no. 6162 (November 29, 2013): 1094–98. https://doi.org/10.1126/science.1241908.
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    • Horton, Janet K., Jen-Tsan Ashley Chi, Jeff Groth, Yingchun Zhou, Chen-Ting Lee, and Joseph Geradts. “Up-regulation of Fas Expression in Human Breast Carcinomas Treated With Preoperative Radiation.” Journal of Womens Health 22, no. 10 (October 1, 2013): 890–890.
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    • Mueller, J. L., Z. T. Harmany, J. K. Mito, S. A. Kennedy, Y. Kim, L. Dodd, J. Geradts, et al. “Quantitative segmentation of fluorescence microscopy images of heterogeneous tissue: Approach for tuning algorithm parameters.” Progress in Biomedical Optics and Imaging  Proceedings of Spie 8587 (May 27, 2013). https://doi.org/10.1117/12.2006429.
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    • Kurokawa, Manabu, Jiyeon Kim, Joseph Geradts, Kenkyo Matsuura, Liu Liu, Xu Ran, Wenle Xia, et al. “A network of substrates of the E3 ubiquitin ligases MDM2 and HUWE1 control apoptosis independently of p53.” Sci Signal 6, no. 274 (May 7, 2013): ra32. https://doi.org/10.1126/scisignal.2003741.
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    • Lyman, Gary H., Jay Baker, Joseph Geradts, Janet Horton, Gretchen Kimmick, Jeffrey Peppercorn, Scott Pruitt, Randall P. Scheri, and E Shelley Hwang. “Multidisciplinary care of patients with early-stage breast cancer.” Surg Oncol Clin N Am 22, no. 2 (April 2013): 299–317. https://doi.org/10.1016/j.soc.2012.12.005.
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    • Brown, J Quincy, Torre M. Bydlon, Stephanie A. Kennedy, Matthew L. Caldwell, Jennifer E. Gallagher, Marlee Junker, Lee G. Wilke, William T. Barry, Joseph Geradts, and Nimmi Ramanujam. “Optical spectral surveillance of breast tissue landscapes for detection of residual disease in breast tumor margins.” Plos One 8, no. 7 (2013): e69906. https://doi.org/10.1371/journal.pone.0069906.
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    • Mueller, Jenna L., Zachary T. Harmany, Jeffrey K. Mito, Stephanie A. Kennedy, Yongbaek Kim, Leslie Dodd, Joseph Geradts, et al. “Quantitative Segmentation of Fluorescence Microscopy Images of Heterogeneous Tissue: Application to the Detection of Residual Disease in Tumor Margins.” Plos One 8, no. 6 (2013): e66198. https://doi.org/10.1371/journal.pone.0066198.
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    • Liao, Shaoxi, Mohamed M. Desouki, Daniel P. Gaile, Lori Shepherd, Norma J. Nowak, Jeffrey Conroy, William T. Barry, and Joseph Geradts. “Differential copy number aberrations in novel candidate genes associated with progression from in situ to invasive ductal carcinoma of the breast.” Genes Chromosomes Cancer 51, no. 12 (December 2012): 1067–78. https://doi.org/10.1002/gcc.21991.
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    • Geradts, J., A. G. De Herreros, Z. Su, J. Burchette, G. Broadwater, and R. E. Bachelder. “Erratum:Nuclear Snail1 and nuclear ZEB1 protein expression in invasive and intraductal human breast carcinomas (Human Pathology (2011) 42 (1125-1131)).” Human Pathology 43, no. 10 (October 1, 2012): 1787. https://doi.org/10.1016/j.humpath.2012.07.001.
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    • Sood, Ashwani K., Hyung Kim, and Joseph Geradts. “PDEF in prostate cancer.” Prostate 72, no. 6 (May 1, 2012): 592–96. https://doi.org/10.1002/pros.21461.
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    • Cheng, Qing, Jeffrey T. Chang, Joseph Geradts, Leonard M. Neckers, Timothy Haystead, Neil L. Spector, and H Kim Lyerly. “Amplification and high-level expression of heat shock protein 90 marks aggressive phenotypes of human epidermal growth factor receptor 2 negative breast cancer.” Breast Cancer Res 14, no. 2 (April 17, 2012): R62. https://doi.org/10.1186/bcr3168.
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    • Cao, X., J. Geradts, M. W. Dewhirst, and H. -. W. Lo. “Upregulation of VEGF-A and CD24 gene expression by the tGLI1 transcription factor contributes to the aggressive behavior of breast cancer cells.” Oncogene 31, no. 1 (January 5, 2012): 104–15. https://doi.org/10.1038/onc.2011.219.
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    • Bydlon, T. M., J. Quincy Brown, S. A. Kennedy, J. E. Gallagher, M. Caldwell, M. Junker, L. G. Wilke, W. T. Barry, J. Geradts, and N. Ramanujam. “Optical spectral imaging for breast margin assessment: A comprehensive assessment of sources of contrast.” Biomedical Optics, Biomed 2012, January 1, 2012. https://doi.org/10.1364/biomed.2012.bw2b.4.
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    • Bydlon, Torre M., William T. Barry, Stephanie A. Kennedy, J Quincy Brown, Jennifer E. Gallagher, Lee G. Wilke, Joseph Geradts, and Nimmi Ramanujam. “Advancing optical imaging for breast margin assessment: an analysis of excisional time, cautery, and patent blue dye on underlying sources of contrast.” Plos One 7, no. 12 (2012): e51418. https://doi.org/10.1371/journal.pone.0051418.
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    • West, Dava, Joseph Geradts, Momen Wahidi, and Victor Roggli. “Endobronchial metastatic breast cancer with pagetoid histology mimicking bronchial pagetoid squamous cell carcinoma in situ.” Hum Pathol 42, no. 11 (November 2011): 1819–22. https://doi.org/10.1016/j.humpath.2011.02.009.
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    • Geradts, Joseph, Antonio Garcia de Herreros, Zuowei Su, James Burchette, Gloria Broadwater, and Robin E. Bachelder. “Nuclear Snail1 and nuclear ZEB1 protein expression in invasive and intraductal human breast carcinomas.” Hum Pathol 42, no. 8 (August 2011): 1125–31. https://doi.org/10.1016/j.humpath.2010.11.004.
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    • Hutchinson, C Blake, and Joseph Geradts. “Histiocytoid carcinoma of the male breast.” Ann Diagn Pathol 15, no. 3 (June 2011): 190–93. https://doi.org/10.1016/j.anndiagpath.2010.02.008.
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    • Desouki, Mohamed M., Shaoxi Liao, Jeffrey Conroy, Norma J. Nowak, Lori Shepherd, Daniel P. Gaile, and Joseph Geradts. “The genomic relationship between primary breast carcinomas and their nodal metastases.” Cancer Invest 29, no. 4 (May 2011): 300–307. https://doi.org/10.3109/07357907.2011.568564.
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    • Desouki, Mohamed M., Shaoxi Liao, Huayi Huang, Jeffrey Conroy, Norma J. Nowak, Lori Shepherd, Daniel P. Gaile, and Joseph Geradts. “Identification of metastasis-associated breast cancer genes using a high-resolution whole genome profiling approach.” J Cancer Res Clin Oncol 137, no. 5 (May 2011): 795–809. https://doi.org/10.1007/s00432-010-0937-1.
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    • Pilie, Patrick G., Catherine Ibarra-Drendall, Michelle M. Troch, Gloria Broadwater, William T. Barry, Emanuel F. Petricoin, Julia D. Wulfkuhle, et al. “Protein microarray analysis of mammary epithelial cells from obese and nonobese women at high risk for breast cancer: feasibility data.” Cancer Epidemiol Biomarkers Prev 20, no. 3 (March 2011): 476–82. https://doi.org/10.1158/1055-9965.EPI-10-0847.
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    • Adamo, Barbara, Allison M. Deal, Emily Burrows, Joseph Geradts, Erika Hamilton, Kimberly L. Blackwell, Chad Livasy, et al. “Phosphatidylinositol 3-kinase pathway activation in breast cancer brain metastases.” Breast Cancer Res 13, no. 6 (2011): R125. https://doi.org/10.1186/bcr3071.
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    • West, D., J. Geradts, M. Wahidi, and V. Roggli. “Endobronchial metastatic breast cancer with pagetoid histology mimicking bronchial pagetoid squamous cell carcinoma in situ.” Human Pathology 42, no. 11 (January 1, 2011): 1819–22. https://doi.org/10.1016/j.humpath.2011.03.004.
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    • O’Brien, Katie M., Stephen R. Cole, Chiu-Kit Tse, Charles M. Perou, Lisa A. Carey, William D. Foulkes, Lynn G. Dressler, Joseph Geradts, and Robert C. Millikan. “Intrinsic breast tumor subtypes, race, and long-term survival in the Carolina Breast Cancer Study.” Clin Cancer Res 16, no. 24 (December 15, 2010): 6100–6110. https://doi.org/10.1158/1078-0432.CCR-10-1533.
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    • Geradts, Joseph, Sarah M. Bean, Rex C. Bentley, and William T. Barry. “The oncotype DX recurrence score is correlated with a composite index including routinely reported pathobiologic features.” Cancer Invest 28, no. 9 (November 2010): 969–77. https://doi.org/10.3109/07357907.2010.512600.
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    • Brown, J. Q., T. M. Bydlon, S. A. Kennedy, J. Geradts, L. G. Wilke, W. Barry, L. M. Richards, M. K. Junker, J. Gallagher, and N. Ramanujam. “Assessment of breast tumor margins via quantitative diffuse reflectance imaging.” Progress in Biomedical Optics and Imaging  Proceedings of Spie 7573 (May 7, 2010). https://doi.org/10.1117/12.841949.
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    • Barry, William T., Dawn N. Kernagis, Holly K. Dressman, Ryan J. Griffis, J’vonne D. Hunter, John A. Olson, Jeff R. Marks, et al. “Intratumor heterogeneity and precision of microarray-based predictors of breast cancer biology and clinical outcome.” J Clin Oncol 28, no. 13 (May 1, 2010): 2198–2206. https://doi.org/10.1200/JCO.2009.26.7245.
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    • Bydlon, Torre M., Stephanie A. Kennedy, Lisa M. Richards, J Quincy Brown, Bing Yu, Marlee K. Junker, Jennifer Gallagher, Joseph Geradts, Lee G. Wilke, and Nimmi Ramanujam. “Performance metrics of an optical spectral imaging system for intra-operative assessment of breast tumor margins.” Opt Express 18, no. 8 (April 12, 2010): 8058–76. https://doi.org/10.1364/OE.18.008058.
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    • Brown, J Quincy, Torre M. Bydlon, Lisa M. Richards, Bing Yu, Stephanie A. Kennedy, Joseph Geradts, Lee G. Wilke, et al. “Optical assessment of tumor resection margins in the breast.” Ieee J Sel Top Quantum Electron 16, no. 3 (March 1, 2010): 530–44. https://doi.org/10.1109/jstqe.2009.2033257.
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    • Kennedy, Stephanie, Joseph Geradts, Torre Bydlon, J Quincy Brown, Jennifer Gallagher, Marlee Junker, William Barry, Nimmi Ramanujam, and Lee Wilke. “Optical breast cancer margin assessment: an observational study of the effects of tissue heterogeneity on optical contrast.” Breast Cancer Res 12, no. 6 (2010): R91. https://doi.org/10.1186/bcr2770.
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    • Ramanujam, N., J. Brown, T. M. Bydlon, S. A. Kennedy, L. M. Richards, M. K. Junker, J. Gallagher, W. T. Barry, L. G. Wilke, and J. Geradts. “Quantitative spectral reflectance imaging device for intraoperative breast tumor margin assessment.” Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Conference, December 1, 2009, 6554–56.
    • Wilke, Lee G., J Quincy Brown, Torre M. Bydlon, Stephanie A. Kennedy, Lisa M. Richards, Marlee K. Junker, Jennifer Gallagher, William T. Barry, Joseph Geradts, and Nimmi Ramanujam. “Rapid noninvasive optical imaging of tissue composition in breast tumor margins.” Am J Surg 198, no. 4 (October 2009): 566–74. https://doi.org/10.1016/j.amjsurg.2009.06.018.
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    • Sood, Ashwani K., Jianmin Wang, Paulette Mhawech-Fauceglia, Bagirathan Jana, Ping Liang, and Joseph Geradts. “Sam-pointed domain containing Ets transcription factor in luminal breast cancer pathogenesis.” Cancer Epidemiol Biomarkers Prev 18, no. 6 (June 2009): 1899–1903. https://doi.org/10.1158/1055-9965.EPI-09-0055.
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    • Sood, Ashwani, Jianmin Wang, Bagirathan Janarthanan, Ping Liang, Hyung Kim, and Joseph Geradts. “Prostate derived Ets factor (PDEF), an emerging biomarker in cancer.” Cancer Research 69 (May 1, 2009).
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    • Geradts, Joseph. “Re: KAI1/CD82 is a novel target of estrogen receptor-mediated gene repression and downregulated in primary human breast cancer (Int J Cancer 123: 2239-2246, 2008).” Int J Cancer 124, no. 9 (May 1, 2009): 2243–44. https://doi.org/10.1002/ijc.24156.
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    • Harvey, Shashikumar, Shin Kohga, Sheila N. J. Sait, Gabor Markus, Thelma C. Hurd, Maisie Martinick, Joseph Geradts, Rakhee Saxena, and John F. Gibbs. “Co-expression of urokinase with haptoglobin in human carcinomas.” J Surg Res 152, no. 2 (April 2009): 189–97. https://doi.org/10.1016/j.jss.2008.06.016.
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    • Brown, J Quincy, Lee G. Wilke, Joseph Geradts, Stephanie A. Kennedy, Gregory M. Palmer, and Nirmala Ramanujam. “Quantitative optical spectroscopy: a robust tool for direct measurement of breast cancer vascular oxygenation and total hemoglobin content in vivo.” Cancer Res 69, no. 7 (April 1, 2009): 2919–26. https://doi.org/10.1158/0008-5472.CAN-08-3370.
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    • Ramanujam, Nimmi, J. Brown, Torre M. Bydlon, Stephanie A. Kennedy, Lisa M. Richards, Marlee K. Junker, Jennifer Gallagher, William T. Barry, Lee G. Wilke, and Joseph Geradts. “Quantitative spectral reflectance imaging device for intraoperative breast tumor margin assessment.” Annu Int Conf Ieee Eng Med Biol Soc 2009 (2009): 6554–56. https://doi.org/10.1109/IEMBS.2009.5334501.
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    • Ramanujam, N., J. Brown, T. M. Bydlon, S. A. Kennedy, L. M. Richards, M. K. Junker, J. Gallagher, W. T. Barry, L. G. Wilke, and J. Geradts. “Quantitative spectral reflectance imaging device for intraoperative breast tumor margin assessment.” Conference Proceedings : ... Annual International Conference of the Ieee Engineering in Medicine and Biology Society. Ieee Engineering in Medicine and Biology Society. Conference 2009 (2009): 6554–56.
    • Millikan, R. C., B. Newman, C. K. Tse, P. G. Moorman, K. Conway, L. G. Dressler, L. V. Smith, et al. “Epidemiology of basal-like breast cancer (Breast Cancer Research and Treatment DOI: 10.1007/s10549-007-9632-6).” Breast Cancer Research and Treatment 109, no. 1 (May 1, 2008): 141. https://doi.org/10.1007/s10549-007-9790-6.
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    • Millikan, Robert C., Beth Newman, Chiu-Kit Tse, Patricia G. Moorman, Kathleen Conway, Lynn G. Dressler, Lisa V. Smith, et al. “Epidemiology of basal-like breast cancer.” Breast Cancer Res Treat 109, no. 1 (May 2008): 123–39. https://doi.org/10.1007/s10549-007-9632-6.
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    • Sood, Ashwani K., Rakhee Saxena, Jeff Groth, Mohamed M. Desouki, Chalong Cheewakriangkrai, Kerry J. Rodabaugh, Chitta S. Kasyapa, and Joseph Geradts. “Expression characteristics of prostate-derived Ets factor support a role in breast and prostate cancer progression.” Hum Pathol 38, no. 11 (November 2007): 1628–38. https://doi.org/10.1016/j.humpath.2007.03.010.
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    • Huang, Huayi, Khalid Sossey-Alaoui, Sarah H. Beachy, and Joseph Geradts. “The tetraspanin superfamily member NET-6 is a new tumor suppressor gene.” J Cancer Res Clin Oncol 133, no. 10 (October 2007): 761–69. https://doi.org/10.1007/s00432-007-0221-1.
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    • Heller, Gerwin, Joseph Geradts, Barbara Ziegler, Irene Newsham, Martin Filipits, Eva-Maria Markis-Ritzinger, Daniela Kandioler, et al. “Downregulation of TSLC1 and DAL-1 expression occurs frequently in breast cancer.” Breast Cancer Res Treat 103, no. 3 (July 2007): 283–91. https://doi.org/10.1007/s10549-006-9377-7.
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    • Desouki, Mohamed M., Joseph Geradts, Beatrice Milon, Renty B. Franklin, and Leslie C. Costello. “hZip2 and hZip3 zinc transporters are down regulated in human prostate adenocarcinomatous glands.” Mol Cancer 6 (June 5, 2007): 37. https://doi.org/10.1186/1476-4598-6-37.
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    • Javle, M. M., J. Yu, T. Khoury, K. S. Chadha, R. V. Iyer, J. Foster, B. W. Kuvshinoff, et al. “Erratum: Hepatology: Akt expression may predict favorable prognosis in cholangiocarcinoma (Journal of Gastroenterology and Hepatology 21 (1394-1398) DOI: 10.1111/j.1440-1746.2006.04373.x).” Journal of Gastroenterology and Hepatology (Australia) 22, no. 1 (January 1, 2007): 145. https://doi.org/10.1111/j.1440-1746.2007.04810.x.
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    • Javle, Milind M., Jihnhee Yu, Thaer Khoury, Krishdeep C. Chadha, Renuka V. Iyer, Jason Foster, Boris W. Kuvshinoff, et al. “Hepatology: Akt expression may predict favorable prognosis in cholangiocarcinoma. (vol 21, pg 1394, 2006).” Journal of Gastroenterology and Hepatology 22, no. 1 (January 1, 2007): 145–145. https://doi.org/10.1111/j.1440-1748.2007.04810.x.
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    • Javle, Milind M., Jihnhee Yu, Thaer Khoury, Krishdeep S. Chadha, Renuka V. Iyer, Jason Foster, Boris W. Kuvshinoff, et al. “Akt expression may predict favorable prognosis in cholangiocarcinoma.” J Gastroenterol Hepatol 21, no. 11 (November 2006): 1744–51. https://doi.org/10.1111/j.1440-1746.2006.04373.x.
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    • Yang, Jun, Nithya Ramnath, Kirsten B. Moysich, Harold L. Asch, Helen Swede, Sadir J. Alrawi, Joel Huberman, Joseph Geradts, John S. J. Brooks, and Dongfeng Tan. “Prognostic significance of MCM2, Ki-67 and gelsolin in non-small cell lung cancer.” Bmc Cancer 6 (August 1, 2006): 203. https://doi.org/10.1186/1471-2407-6-203.
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    • Carey, Lisa A., Charles M. Perou, Chad A. Livasy, Lynn G. Dressler, David Cowan, Kathleen Conway, Gamze Karaca, et al. “Race, breast cancer subtypes, and survival in the Carolina Breast Cancer Study.” Jama 295, no. 21 (June 7, 2006): 2492–2502. https://doi.org/10.1001/jama.295.21.2492.
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    • Watwe, V., M. Javle, D. Lawrence, J. Groth, R. Iyer, D. El-Hajjar, and J. Geradts. “Cyclooxygenase-2 (COX-2) levels before and after chemotherapy: a study in rectal cancer.” American Journal of Clinical Oncology : The Official Publication of the American Radium Society. 28, no. 6 (December 2005): 560–64.
    • Watwe, Veena, Milind Javle, David Lawrence, Jeffrey Groth, Renuka Iyer, Dany El-Hajjar, and Joseph Geradts. “Cyclooxygenase-2 (COX-2) levels before and after chemotherapy: a study in rectal cancer.” Am J Clin Oncol 28, no. 6 (December 2005): 560–64. https://doi.org/10.1097/01.coc.0000182476.34375.17.
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    • Bush, Eric, Joseph Geradts, and Tracey O’Connor. “An unusual cause of cholecystitis?” Am J Clin Oncol 28, no. 5 (October 2005): 529–30. https://doi.org/10.1097/01.coc.0000162421.40734.8a.
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    • Lark, Amy L., Chad A. Livasy, Lynn Dressler, Dominic T. Moore, Robert C. Millikan, Joseph Geradts, Mary Iacocca, et al. “High focal adhesion kinase expression in invasive breast carcinomas is associated with an aggressive phenotype.” Mod Pathol 18, no. 10 (October 2005): 1289–94. https://doi.org/10.1038/modpathol.3800424.
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    • Varma, G., R. Varma, H. Huang, A. Pryshchepava, J. Groth, D. Fleming, N. J. Nowak, et al. “Array comparative genomic hybridisation (aCGH) analysis of premenopausal breast cancers from a nuclear fallout area and matched cases from Western New York.” Br J Cancer 93, no. 6 (September 19, 2005): 699–708. https://doi.org/10.1038/sj.bjc.6602784.
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    • Zöchbauer-Müller, Sabine, Kwun M. Fong, Joseph Geradts, Xie Xu, Sonja Seidl, Adelheid End-Pfützenreuter, György Lang, et al. “Expression of the candidate tumor suppressor gene hSRBC is frequently lost in primary lung cancers with and without DNA methylation.” Oncogene 24, no. 41 (September 15, 2005): 6249–55. https://doi.org/10.1038/sj.onc.1208775.
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    • Singh, Keshav K., Mariola Kulawiec, Ivan Still, Mohamed M. Desouki, Joseph Geradts, and Sei-Ichi Matsui. “Inter-genomic cross talk between mitochondria and the nucleus plays an important role in tumorigenesis.” Gene 354 (July 18, 2005): 140–46. https://doi.org/10.1016/j.gene.2005.03.027.
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    • Huang, Huayi, Jeff Groth, Khalid Sossey-Alaoui, Lesleyann Hawthorn, Stephanie Beall, and Joseph Geradts. “Aberrant expression of novel and previously described cell membrane markers in human breast cancer cell lines and tumors.” Clin Cancer Res 11, no. 12 (June 15, 2005): 4357–64. https://doi.org/10.1158/1078-0432.CCR-04-2107.
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    • Tanvetyanon, Tawee. “Molecular prediction of recurrence of breast cancer.” N Engl J Med 352, no. 15 (April 14, 2005): 1605–7.
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    • Conway, Kathleen, Eloise Parrish, Sharon N. Edmiston, Dawn Tolbert, Chiu-Kit Tse, Joseph Geradts, Chad A. Livasy, Harsharan Singh, Beth Newman, and Robert C. Millikan. “The estrogen receptor-alpha A908G (K303R) mutation occurs at a low frequency in invasive breast tumors: results from a population-based study.” Breast Cancer Res 7, no. 6 (2005): R871–80. https://doi.org/10.1186/bcr1315.
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    • Yang, Jun, Dongfeng Tan, Harold L. Asch, Helen Swede, Gerold Bepler, Joseph Geradts, and Kirsten B. Moysich. “Prognostic significance of gelsolin expression level and variability in non-small cell lung cancer.” Lung Cancer 46, no. 1 (October 2004): 29–42. https://doi.org/10.1016/j.lungcan.2004.03.022.
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    • Wilkinson, Neal W., Jennifer D. Black, Elena Roukhadze, Deborah Driscoll, Shannon Smiley, Hisakazu Hoshi, Joseph Geradts, Milind Javle, and Michael Brattain. “Epidermal growth factor receptor expression correlates with histologic grade in resected esophageal adenocarcinoma.” J Gastrointest Surg 8, no. 4 (2004): 448–53. https://doi.org/10.1016/j.gassur.2004.01.006.
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    • Winston, Janet S., Joseph Geradts, Dong Feng Liu, and Paul C. Stomper. “Microtome shaving radiography: demonstration of loss of mammographic microcalcifications during histologic sectioning.” Breast J 10, no. 3 (2004): 200–203. https://doi.org/10.1111/j.1075-122X.2004.21300.x.
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    • Maitra, A., D. E. Hansel, P. Argani, R. Ashfaq, A. Rahman, A. Naji, S. Deng, et al. “Global Expression Analysis of Well-Differentiated Pancreatic Endocrine Neoplasms Using Oligonucleotide Microarrays.” Clinical Cancer Research 9, no. 16 I (December 1, 2003): 5988–95.
    • Maitra, Anirban, Donna E. Hansel, Pedram Argani, Raheela Ashfaq, Ayman Rahman, Ali Naji, Shaoping Deng, et al. “Global expression analysis of well-differentiated pancreatic endocrine neoplasms using oligonucleotide microarrays.” Clin Cancer Res 9, no. 16 Pt 1 (December 1, 2003): 5988–95.
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    • Rosty, Christophe, Joseph Geradts, Norihiro Sato, Robb E. Wilentz, Helen Roberts, Taylor Sohn, John L. Cameron, Charles J. Yeo, Ralph H. Hruban, and Michael Goggins. “p16 Inactivation in pancreatic intraepithelial neoplasias (PanINs) arising in patients with chronic pancreatitis.” Am J Surg Pathol 27, no. 12 (December 2003): 1495–1501. https://doi.org/10.1097/00000478-200312000-00001.
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    • Stomper, Paul C., Joseph Geradts, Stephen B. Edge, and Ellis G. Levine. “Mammographic predictors of the presence and size of invasive carcinomas associated with malignant microcalcification lesions without a mass.” Ajr Am J Roentgenol 181, no. 6 (December 2003): 1679–84. https://doi.org/10.2214/ajr.181.6.1811679.
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    • Furberg, H., R. C. Millikan, J. Geradts, M. D. Gammon, L. G. Dressler, C. B. Ambrosone, and B. Newman. “Reproductive factors in relation to breast cancer characterized by p53 protein expression (United States).” Cancer Causes Control 14, no. 7 (September 2003): 609–18. https://doi.org/10.1023/a:1025682410937.
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    • Hansel, Donna E., Ayman Rahman, Manuel Hidalgo, Paul J. Thuluvath, Keith D. Lillemoe, Richard Schulick, Ja-Lok Ku, et al. “Identification of novel cellular targets in biliary tract cancers using global gene expression technology.” Am J Pathol 163, no. 1 (July 2003): 217–29. https://doi.org/10.1016/S0002-9440(10)63645-0.
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    • Millikan, Robert, Allison Eaton, Kendra Worley, Lorna Biscocho, Elizabeth Hodgson, Wen-Yi Huang, Joseph Geradts, et al. “HER2 codon 655 polymorphism and risk of breast cancer in African Americans and whites.” Breast Cancer Res Treat 79, no. 3 (June 2003): 355–64. https://doi.org/10.1023/a:1024068525763.
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    • Parwani, Anil V., Joseph Geradts, Eric Caspers, G Johan Offerhaus, Charles J. Yeo, John L. Cameron, David S. Klimstra, Anirban Maitra, Ralph H. Hruban, and Pedram Argani. “Immunohistochemical and genetic analysis of non-small cell and small cell gallbladder carcinoma and their precursor lesions.” Mod Pathol 16, no. 4 (April 2003): 299–308. https://doi.org/10.1097/01.MP.0000062656.60581.AA.
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    • Bhagat, Vishal, Milind Javle, and Joseph Geradts. “Carcinoma of the esophagus with mixed basaloid squamous and glandular differentiation: a distinct histological presentation.” Int J Gastrointest Cancer 34, no. 2–3 (2003): 139–42. https://doi.org/10.1385/IJGC:34:2-3:139.
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    • Geradts, Joseph. “Abrogation of the RB-p16 tumor suppressor pathway in human lung cancer.” Methods Mol Med 74 (2003): 89–99. https://doi.org/10.1385/1-59259-323-2:89.
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    • Vo, Q. N., J. Geradts, D. A. Boudreau, J. C. Bravo, and B. G. Schneider. “CDKN2A promoter methylation in gastric adenocarcinomas: clinical variables.” Hum Pathol 33, no. 12 (December 2002): 1200–1204. https://doi.org/10.1053/hupa.2002.130108.
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    • Vestey, Sarah, and Zoë Winters. “Correspondence re: Geradts J, Wilentz RE, Roberts H. Immunohistochemical detection of the alternate ink4a-encoded tumor suppressor protein p14(arf) in archival human cancers and cell lines using commercial antibodies: correlation with p16(ink4a) expression. Mod pathol 2001;14:1162-68.” Mod Pathol 15, no. 10 (October 2002): 1106. https://doi.org/10.1038/modpathol.3880662.
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    • Wilson, Katherine S., Helen Roberts, Russell Leek, Adrian L. Harris, and Joseph Geradts. “Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cell lines and tissues.” Am J Pathol 161, no. 4 (October 2002): 1171–85. https://doi.org/10.1016/S0002-9440(10)64394-5.
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    • Furberg, Helena, R. C. Millikan, J. Geradts, M. D. Gammon, L. G. Dressler, C. B. Ambrosone, and B. Newman. “Environmental factors in relation to breast cancer characterized by p53 protein expression.” Cancer Epidemiol Biomarkers Prev 11, no. 9 (September 2002): 829–35.
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    • Vo, Q. N., J. Geradts, M. L. Gulley, D. A. Boudreau, J. C. Bravo, and B. G. Schneider. “Epstein-Barr virus in gastric adenocarcinomas: association with ethnicity and CDKN2A promoter methylation.” J Clin Pathol 55, no. 9 (September 2002): 669–75. https://doi.org/10.1136/jcp.55.9.669.
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    • Conway, Kathleen, Sharon N. Edmiston, Lisa Cui, S Scott Drouin, Jingzhong Pang, Mei He, Chiu-Kit Tse, et al. “Prevalence and spectrum of p53 mutations associated with smoking in breast cancer.” Cancer Res 62, no. 7 (April 1, 2002): 1987–95.
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    • Geradts, J. “Erratum: Immunohistochemical detection of the alternate INK4a-encoded tumor suppressor protein p14^ARF in archival human cancers and cell lines using commercial antibodies: Correlation with p16^INK4a expression (Modern pathology (2001) 14:11 (1162-1168)).” Modern Pathology 15, no. 1 (January 1, 2002): 76.
    • Geradts, J., R. E. Wilentz, and H. Roberts. “Immunohistochemical [corrected] detection of the alternate INK4a-encoded tumor suppressor protein p14(ARF) in archival human cancers and cell lines using commercial antibodies: correlation with p16(INK4a) expression.” Mod Pathol 14, no. 11 (November 2001): 1162–68. https://doi.org/10.1038/modpathol.3880452.
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    • Boecker, W., H. Buerger, K. Schmitz, I. A. Ellis, P. J. van Diest, H. P. Sinn, J. Geradts, R. Diallo, C. Poremba, and H. Herbst. “Ductal epithelial proliferations of the breast: a biological continuum? Comparative genomic hybridization and high-molecular-weight cytokeratin expression patterns.” J Pathol 195, no. 4 (November 2001): 415–21. https://doi.org/10.1002/path.982.
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    • Maitra, A., H. Roberts, A. G. Weinberg, and J. Geradts. “Aberrant expression of tumor suppressor proteins in the Ewing family of tumors.” Arch Pathol Lab Med 125, no. 9 (September 2001): 1207–12. https://doi.org/10.5858/2001-125-1207-AEOTSP.
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    • Furberg, H., R. Millikan, L. Dressler, B. Newman, and J. Geradts. “Tumor characteristics in African American and white women.” Breast Cancer Res Treat 68, no. 1 (July 2001): 33–43. https://doi.org/10.1023/a:1017994726207.
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    • Zöchbauer-Müller, S., K. M. Fong, A. Maitra, S. Lam, J. Geradts, R. Ashfaq, A. K. Virmani, S. Milchgrub, A. F. Gazdar, and J. D. Minna. “5' CpG island methylation of the FHIT gene is correlated with loss of gene expression in lung and breast cancer.” Cancer Res 61, no. 9 (May 1, 2001): 3581–85.
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    • Maitra, A., H. Roberts, A. G. Weinberg, and J. Geradts. “Loss of p16(INK4a) expression correlates with decreased survival in pediatric osteosarcomas.” Int J Cancer 95, no. 1 (January 20, 2001): 34–38. https://doi.org/10.1002/1097-0215(20010120)95:1<34::aid-ijc1006>3.0.co;2-v.
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    • Creager, A. J., J. A. Cohen, and J. Geradts. “Aberrant expression of cell-cycle regulatory proteins in human mesenchymal neoplasia.” Cancer Detect Prev 25, no. 2 (2001): 123–31.
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    • Geradts, J., R. Leek, A. L. Harris, and K. S. Wilson. “Differential gene expression patterns in HER2/neu-positive and -negative breast cancer cells.” Breast Cancer Research and Treatment 69, no. 3 (January 1, 2001): 233.
    • Lombardi, D. P., K. M. Wilson, E. Michalopoulos, H. Conjeaud, and J. Geradts. “Gene amplification of HER-2/neu is inversely correlated with loss of expression of the tetraspanin metastasis suppressor gene, KAI1/CD82, in breast cancer samples and cell lines.” Breast Cancer Research and Treatment 69, no. 3 (January 1, 2001): 316.
    • Maitra, A., H. Roberts, A. G. Weinberg, and J. Geradts. “Lymphatic microvessel density as a novel prognostic factor in early-stage invasive cervical cancer.” International Journal of Cancer 95, no. 1 (2001): 29–33. https://doi.org/10.1002/1097-0215(20010120)95:1<29::AID-IJC1005>3.0.CO;2-W.
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    • Zöchbauer-Müller, S., K. M. Fong, A. K. Virmani, J. Geradts, A. F. Gazdar, and J. D. Minna. “Aberrant promoter methylation of multiple genes in non-small cell lung cancers.” Cancer Res 61, no. 1 (January 1, 2001): 249–55.
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    • Geradts, J., and C. D. Ingram. “Abnormal expression of cell cycle regulatory proteins in ductal and lobular carcinomas of the breast.” Mod Pathol 13, no. 9 (September 2000): 945–53. https://doi.org/10.1038/modpathol.3880172.
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    • Wistuba, I. I., G. E. Tomlinson, C. Behrens, A. Virmani, J. Geradts, J. L. Blum, J. D. Minna, and A. F. Gazdar. “Two identical triplet sisters carrying a germline BRCA1 gene mutation acquire very similar breast cancer somatic mutations at multiple other sites throughout the genome.” Genes Chromosomes Cancer 28, no. 4 (August 2000): 359–69. https://doi.org/10.1002/1098-2264(200008)28:4<359::aid-gcc1>3.0.co;2-n.
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    • Schmitz, M. J., D. T. Hendricks, J. Farley, R. R. Taylor, J. Geradts, G. S. Rose, and M. J. Birrer. “p27 and cyclin D1 abnormalities in uterine papillary serous carcinoma.” Gynecol Oncol 77, no. 3 (June 2000): 439–45. https://doi.org/10.1006/gyno.2000.5814.
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    • Pisano, E. D., R. E. Johnston, D. Chapman, J. Geradts, M. V. Iacocca, C. A. Livasy, D. B. Washburn, et al. “Human breast cancer specimens: diffraction-enhanced imaging with histologic correlation--improved conspicuity of lesion detail compared with digital radiography.” Radiology 214, no. 3 (March 2000): 895–901. https://doi.org/10.1148/radiology.214.3.r00mr26895.
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    • Geradts, J., K. M. Fong, P. V. Zimmerman, and J. D. Minna. “Loss of Fhit expression in non-small-cell lung cancer: correlation with molecular genetic abnormalities and clinicopathological features.” Br J Cancer 82, no. 6 (March 2000): 1191–97. https://doi.org/10.1054/bjoc.1999.1062.
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    • Geradts, J., R. H. Hruban, M. Schutte, S. E. Kern, and R. Maynard. “Immunohistochemical p16INK4a analysis of archival tumors with deletion, hypermethylation, or mutation of the CDKN2/MTS1 gene. A comparison of four commercial antibodies.” Appl Immunohistochem Mol Morphol 8, no. 1 (March 2000): 71–79. https://doi.org/10.1097/00129039-200003000-00011.
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    • Hilgers, W., B. Groot Koerkamp, J. Geradts, D. J. Tang, C. J. Yeo, R. H. Hruban, and S. E. Kern. “Genomic FHIT analysis in RER+ and RER- adenocarcinomas of the pancreas.” Genes Chromosomes Cancer 27, no. 3 (March 2000): 239–43.
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    • Belchis, D. A., C. D. Gocke, and J. Geradts. “Alterations in the RB, p16, and cyclin D1 cell cycle control pathway in osteosarcomas.” Pediatric Pathology and Molecular Medicine 19, no. 5 (January 1, 2000): 377–89. https://doi.org/10.1080/15513810009168646.
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    • Schneider, B. G., M. L. Gulley, P. Eagan, J. C. Bravo, R. Mera, and J. Geradts. “Loss of p16/CDKN2A tumor suppressor protein in gastric adenocarcinoma is associated with Epstein-Barr virus and anatomic location in the body of the stomach.” Hum Pathol 31, no. 1 (January 2000): 45–50. https://doi.org/10.1016/s0046-8177(00)80197-5.
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    • Fong, K. M., J. Geradts, J. D. Minna, and R. V. Zimmerman. “Fhit expression in non-small cell lung cancer (NSCLC).” Respirology 4, no. SUPPL. 1 (December 1, 1999).
    • Gehrig, P. A., L. Van Le, B. Olatidoye, and J. Geradts. “Estrogen receptor status, determined by immunohistochemistry, as a predictor of the recurrence of stage I endometrial carcinoma.” Cancer 86, no. 10 (November 15, 1999): 2083–89.
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    • Lombardi, D. P., J. Geradts, J. F. Foley, C. Chiao, P. W. Lamb, and J. C. Barrett. “Loss of KAI1 expression in the progression of colorectal cancer.” Cancer Res 59, no. 22 (November 15, 1999): 5724–31.
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    • Dressler, L. G., J. Geradts, M. Burroughs, D. Cowan, R. C. Millikan, and B. Newman. “Policy guidelines for the utilization of formalin-fixed, paraffin-embedded tissue sections: the UNC SPORE experience. University of North Carolina Specialized Program of Research Excellence.” Breast Cancer Res Treat 58, no. 1 (November 1999): 31–39. https://doi.org/10.1023/a:1006354627669.
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    • Birrer, M. J., D. Hendricks, J. Farley, M. J. Sundborg, T. Bonome, M. J. Walts, and J. Geradts. “Abnormal Fhit expression in malignant and premalignant lesions of the cervix.” Cancer Res 59, no. 20 (October 15, 1999): 5270–74.
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    • Niehans, G. A., R. A. Kratzke, M. K. Froberg, D. M. Aeppli, P. L. Nguyen, and J. Geradts. “G1 checkpoint protein and p53 abnormalities occur in most invasive transitional cell carcinomas of the urinary bladder.” Br J Cancer 80, no. 8 (June 1999): 1175–84. https://doi.org/10.1038/sj.bjc.6990483.
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    • Chen, W. D., J. Geradts, M. M. Keane, S. Lipkowitz, M. Zajac-Kaye, and F. J. Kaye. “The 100-kDa proteolytic fragment of RB is retained predominantly within the nuclear compartment of apoptotic cells.” Mol Cell Biol Res Commun 1, no. 3 (June 1999): 216–20. https://doi.org/10.1006/mcbr.1999.0132.
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    • Geradts, J., R. Maynard, M. J. Birrer, D. Hendricks, S. L. Abbondanzo, K. M. Fong, J. C. Barrett, and D. P. Lombardi. “Frequent loss of KAI1 expression in squamous and lymphoid neoplasms. An immunohistochemical study of archival tissues.” Am J Pathol 154, no. 6 (June 1999): 1665–71. https://doi.org/10.1016/S0002-9440(10)65422-3.
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    • Geradts, J., K. M. Fong, P. V. Zimmerman, R. Maynard, and J. D. Minna. “Correlation of abnormal RB, p16ink4a, and p53 expression with 3p loss of heterozygosity, other genetic abnormalities, and clinical features in 103 primary non-small cell lung cancers.” Clin Cancer Res 5, no. 4 (April 1999): 791–800.
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    • Wilentz, R. E., J. Geradts, R. Maynard, G. J. Offerhaus, M. Kang, M. Goggins, C. J. Yeo, S. E. Kern, and R. H. Hruban. “Inactivation of the p16 (INK4A) tumor-suppressor gene in pancreatic duct lesions: loss of intranuclear expression.” Cancer Res 58, no. 20 (October 15, 1998): 4740–44.
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    • Coxon, A. B., J. M. Ward, J. Geradts, G. A. Otterson, M. Zajac-Kaye, and F. J. Kaye. “RET cooperates with RB/p53 inactivation in a somatic multi-step model for murine thyroid cancer.” Oncogene 17, no. 12 (September 24, 1998): 1625–28. https://doi.org/10.1038/sj.onc.1202381.
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    • Frizelle, S. P., J. Grim, J. Zhou, P. Gupta, D. T. Curiel, J. Geradts, and R. A. Kratzke. “Re-expression of p16INK4a in mesothelioma cells results in cell cycle arrest, cell death, tumor suppression and tumor regression.” Oncogene 16, no. 24 (June 18, 1998): 3087–95. https://doi.org/10.1038/sj.onc.1201870.
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    • Geradts, J., J. W. Andriko, and S. L. Abbondanzo. “Loss of tumor suppressor gene expression in high-grade but not low-grade non-Hodgkin's lymphomas.” Am J Clin Pathol 109, no. 6 (June 1998): 669–74. https://doi.org/10.1093/ajcp/109.6.669.
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    • Gulley, M. L., J. M. Nicholls, B. G. Schneider, M. B. Amin, J. Y. Ro, and J. Geradts. “Nasopharyngeal carcinomas frequently lack the p16/MTS1 tumor suppressor protein but consistently express the retinoblastoma gene product.” Am J Pathol 152, no. 4 (April 1998): 865–69.
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    • Otterson, G. A., G. H. Xiao, J. Geradts, F. Jin, W. D. Chen, W. Niklinska, F. J. Kaye, and R. S. Yeung. “Protein expression and functional analysis of the FHIT gene in human tumor cells.” J Natl Cancer Inst 90, no. 6 (March 18, 1998): 426–32. https://doi.org/10.1093/jnci/90.6.426.
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    • Cohen, J. A., and J. Geradts. “Loss of RB and MTS1/CDKN2 (p16) expression in human sarcomas.” Hum Pathol 28, no. 8 (August 1997): 893–98. https://doi.org/10.1016/s0046-8177(97)90003-4.
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    • Schutte, M., R. H. Hruban, J. Geradts, R. Maynard, W. Hilgers, S. K. Rabindran, C. A. Moskaluk, et al. “Abrogation of the Rb/p16 tumor-suppressive pathway in virtually all pancreatic carcinomas.” Cancer Res 57, no. 15 (August 1, 1997): 3126–30.
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    • Parker, M. F., G. F. Arroyo, J. Geradts, A. L. Sabichi, R. C. Park, R. R. Taylor, and M. J. Birrer. “Molecular characterization of adenocarcinoma of the cervix.” Gynecol Oncol 64, no. 2 (February 1997): 242–51. https://doi.org/10.1006/gyno.1996.4580.
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    • Kratzke, R. A., T. M. Greatens, J. B. Rubins, M. A. Maddaus, D. E. Niewoehner, G. A. Niehans, and J. Geradts. “Rb and p16INK4a expression in resected non-small cell lung tumors.” Cancer Res 56, no. 15 (August 1, 1996): 3415–20.
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    • Geradts, J., and P. A. Wilson. “High frequency of aberrant p16(INK4A) expression in human breast cancer.” Am J Pathol 149, no. 1 (July 1996): 15–20.
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    • Geradts, J., R. A. Kratzke, S. Crush-Stanton, S. F. Wen, and C. E. Lincoln. “Wild-type and mutant retinoblastoma protein in paraffin sections.” Mod Pathol 9, no. 3 (March 1996): 339–47.
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    • Huang, L., D. Lang, J. Geradts, T. Obara, A. J. Klein-Szanto, H. T. Lynch, and B. A. Ruggeri. “Molecular and immunochemical analyses of RB1 and cyclin D1 in human ductal pancreatic carcinomas and cell lines.” Mol Carcinog 15, no. 2 (February 1996): 85–95. https://doi.org/10.1002/(SICI)1098-2744(199602)15:2<85::AID-MC1>3.0.CO;2-Q.
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    • Kratzke, R. A., G. A. Otterson, C. E. Lincoln, S. Ewing, H. Oie, J. Geradts, and F. J. Kaye. “Immunohistochemical analysis of the p16INK4 cyclin-dependent kinase inhibitor in malignant mesothelioma.” J Natl Cancer Inst 87, no. 24 (December 20, 1995): 1870–75. https://doi.org/10.1093/jnci/87.24.1870.
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    • Geradts, J., R. A. Kratzke, G. A. Niehans, and C. E. Lincoln. “Immunohistochemical detection of the cyclin-dependent kinase inhibitor 2/multiple tumor suppressor gene 1 (CDKN2/MTS1) product p16INK4A in archival human solid tumors: correlation with retinoblastoma protein expression.” Cancer Res 55, no. 24 (December 15, 1995): 6006–11.
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    • Millikan, R., L. Dressler, J. Geradts, and M. Graham. “The need for epidemiologic studies of in-situ carcinoma of the breast.” Breast Cancer Res Treat 35, no. 1 (July 1995): 65–77. https://doi.org/10.1007/BF00694747.
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    • Newman, B., P. G. Moorman, R. Millikan, B. F. Qaqish, J. Geradts, T. E. Aldrich, and E. T. Liu. “The Carolina Breast Cancer Study: integrating population-based epidemiology and molecular biology.” Breast Cancer Res Treat 35, no. 1 (July 1995): 51–60. https://doi.org/10.1007/BF00694745.
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    • Geradts, J., S. X. Hu, C. E. Lincoln, W. F. Benedict, and H. J. Xu. “Aberrant RB gene expression in routinely processed, archival tumor tissues determined by three different anti-RB antibodies.” Int J Cancer 58, no. 2 (July 15, 1994): 161–67. https://doi.org/10.1002/ijc.2910580203.
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    • Geradts, J., and W. W. McLendon. “Pathology and laboratory medicine.” Jama 271, no. 21 (June 1, 1994): 1700–1701.
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    • Kratzke, R. A., G. A. Otterson, A. Hogg, A. B. Coxon, J. Geradts, J. K. Cowell, and F. J. Kaye. “Partial inactivation of the RB product in a family with incomplete penetrance of familial retinoblastoma and benign retinal tumors.” Oncogene 9, no. 5 (May 1994): 1321–26.
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    • Wen, S. F., M. Nodelman, K. Nared-Hood, J. Duncan, J. Geradts, and H. M. Shepard. “Retinoblastoma protein monoclonal antibodies with novel characteristics.” J Immunol Methods 169, no. 2 (March 10, 1994): 231–40. https://doi.org/10.1016/0022-1759(94)90267-4.
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    • Geradts, J., J. Y. Chen, E. K. Russell, J. R. Yankaskas, L. Nieves, and J. D. Minna. “Human lung cancer cell lines exhibit resistance to retinoic acid treatment.” Cell Growth Differ 4, no. 10 (October 1993): 799–809.
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    • Kratzke, R. A., E. Shimizu, J. Geradts, J. L. Gerster, S. Segal, G. A. Otterson, and F. J. Kaye. “RB-mediated tumor suppression of a lung cancer cell line is abrogated by an extract enriched in extracellular matrix.” Cell Growth Differ 4, no. 8 (August 1993): 629–35.
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    • Geradts, J., M. Warnock, and T. S. Yen. “Use of the polymerase chain reaction in the diagnosis of unsuspected herpes simplex viral pneumonia: report of a case.” Hum Pathol 21, no. 1 (January 1990): 118–21. https://doi.org/10.1016/0046-8177(90)90084-i.
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    • Montag, A. G., J. Geradts, P. K. Hui, and W. A. Franklin. “Chapter 10 Limited expression of myeloid antigens by neuroendocrine tumours of lung.” Lung Cancer 4, no. 1–2 (January 1, 1988): 55–57. https://doi.org/10.1016/S0169-5002(88)80012-6.
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    • Ceriani, R. L., J. Geradts, and J. A. Peterson. “Second international workshop on monoclonal antibodies and breast cancer. San Francisco, November 20-21, 1986.” Breast Cancer Res Treat 10, no. 1 (October 1987): 55–63. https://doi.org/10.1007/BF01806136.
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    • Geradts, J., J. Richards, M. Edery, K. Pang, L. Larson, and S. Nandi. “Heterogeneity in the hormonal responsiveness of clones derived from the 13762NF rat mammary tumor.” Cancer Res 46, no. 4 Pt 2 (April 1986): 1920–27.
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    • Geradts, J., J. Richards, M. Edery, K. Pang, L. Larson, and S. Nandi. “Heterogeneity in the hormonal responsiveness of clones derived from the 13762nf rat mammary tumor.” Cancer Research 46 (January 1, 1986): 1920–27.
    • Geradts, J., J. Richards, and M. Edery. “Heterogeneity in the hormonal responsiveness of clones from the 13762NF rat mammary tumor.” Proceedings of the American Association for Cancer Research VOL. 26 (1985): No.-2.

  • Conference Papers

    • Mohamed, Anas, Aisha Kousar, Jan Wong, Nasreen Vohra, Mahvish Muzaffar, and Joseph Geradts. “Pathobiologic Stratification of Oncotype DX Recurrence Scores and Comparative Validation of 3 Surrogate Models.” In Arch Pathol Lab Med, 146:1258–67, 2022. https://doi.org/10.5858/arpa.2021-0367-OA.
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    • Kochupurakkal, Bose S., Kalindi Parmar, Jean-Bernard Lazaro, Christine Unitt, Qing Zeng, Hunter Reavis, Chirag Ganesa, et al. “Abstract 2796: Development of a RAD51-based assay for determining homologous recombination proficiency and PARP inhibitor sensitivity.” In Cancer Research, 77:2796–2796. American Association for Cancer Research (AACR), 2017. https://doi.org/10.1158/1538-7445.am2017-2796.
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    • Shapiro, Geoffrey I., Khanh T. Do, Sara M. Tolaney, John F. Hilton, James M. Cleary, Andrew Wolanski, Brian Beardslee, et al. “Abstract CT047: Phase 1 dose-escalation study of the CDK inhibitor dinaciclib in combination with the PARP inhibitor veliparib in patients with advanced solid tumors.” In Cancer Research, 77:CT047–CT047. American Association for Cancer Research (AACR), 2017. https://doi.org/10.1158/1538-7445.am2017-ct047.
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    • Evans, Myron K., Joseph Geradts, Courtney Edwards, Arianna Price, Arjun J. Arora, Amy J. Aldrich, Adrian Ramirez, et al. “Abstract LB-015: XIAP induction by the MAPK-eIF4G1 pathway drives NFκB activation in inflammatory breast cancer growth and therapeutic resistance.” In Cancer Research, Vol. 76. American Association for Cancer Research (AACR), 2016. https://doi.org/10.1158/1538-7445.am2016-lb-015.
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    • Khoury, Thaer, Gary Zirpoli, Stephanie M. Cohen, Mihai Merzianu, Melissa Troester, Joseph Geradts, Amber Worral, Wiam Bshara, and Christine Ambrosone. “Comprehensive Evaluation of Ki67 in Luminal/HER2-Negative Breast Cancer in the AMBER Consortium.” In Laboratory Investigation, 96:50A-50A. NATURE PUBLISHING GROUP, 2016.
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    • Khoury, Thaer, Gary Zirpoli, Stephanie M. Cohen, Mihai Merzianu, Melissa Troester, Joseph Geradts, Amber Worral, Wiam Bshara, and Christine Ambrosone. “Comprehensive Evaluation of Ki67 in Luminal/HER2-Negative Breast Cancer in the AMBER Consortium.” In Modern Pathology, 29:50A-50A, 2016.
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    • Evans, Myron K., Scott J. Sauer, Amy J. Aldrich, Joseph Geradts, Peter Vermeulen, Luc Dirix, Steven Van Laere, and Gayathri R. Devi. “Abstract P6-14-05: A novel link between anti-apoptotic signaling, NFκB, and SMAD7 in IBC pathobiology.” In Cancer Research, Vol. 75. American Association for Cancer Research (AACR), 2015. https://doi.org/10.1158/1538-7445.sabcs14-p6-14-05.
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    • Khoury, Thaer, Gary Zirpoli, Stephanie Cohen, Joseph Geradts, Melissa Troester, and Christine Ambrosone. “Correlation of Manual and Image Anlysis Ki-67 Scores in Breast Cancer Tissue Microarrays and Comparison With PAM50 Data.” In Modern Pathology, 28:50A-50A. NATURE PUBLISHING GROUP, 2015.
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    • Khoury, Thaer, Gary Zirpoli, Stephanie Cohen, Joseph Geradts, Melissa Troester, and Christine Ambrosone. “Correlation of Manual and Image Anlysis Ki-67 Scores in Breast Cancer Tissue Microarrays and Comparison With PAM50 Data.” In Laboratory Investigation, 95:50A-50A, 2015.
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    • Geradts, Joseph, Daniel Gaile, Huayi Huang, Jeff Groth, Devin McQuaid, Norma Nowak, Jefrey Conroy, and Mohamed Desouki. “DNA copy number changes associated with nodal metastasis in human breast carcinomas: An array comparative genomic hybridization study.” In Modern Pathology, 19:12–13. NATURE PUBLISHING GROUP, 2006.
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    • Desouki, Mohamed, Daniel Gaile, Huayi Huang, Jeff Groth, Devin McQuaid, Norma Nowak, Jeff Conroy, and Joseph Geradts. “Identification of DNA copy number abnormalities associated with the metastatic phenotype of human breast cancer using a high resolution whole genome approach.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.
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    • Geradts, Joseph, Khalid Sossey-Alaoui, Sarah Hejaily, and Huayi Huang. “The tetraspanin superfamily member NET-6 is a new breast cancer suppressor gene.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.
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    • Geradts, Joseph, Rakhee Saxena, Jeff Groth, Mohamed Desouki, C Halong Cheewakriangkrai, Kerry Rodabaugh, and Ashwani Sood. “Frequent overexpression of prostate derived ets factor (PDEF) protein in breast cancer progression.” In Cancer Research, Vol. 66. AMER ASSOC CANCER RESEARCH, 2006.
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