Skip to main content

Joshua Paul Spaete

Assistant Professor of Medicine
Medicine, Gastroenterology

Selected Publications


Quality Assurance in Endoscopic Infection Control, Disposable Duodenoscopes, and the Environmental Impact of Endoscopy

Journal Article Techniques and Innovations in Gastrointestinal Endoscopy · January 1, 2022 Increased attention has been directed in recent years to the reprocessing of gastrointestinal endoscopes, largely driven by concerns over infectious complications linked to duodenoscopes. Duodenoscopes clearly present numerous challenges to effective repro ... Full text Cite

Setting minimum standards for training in EUS and ERCP: results from a prospective multicenter study evaluating learning curves and competence among advanced endoscopy trainees.

Conference Gastrointest Endosc · June 2019 BACKGROUND AND AIMS: Minimum EUS and ERCP volumes that should be offered per trainee in "high quality" advanced endoscopy training programs (AETPs) are not established. We aimed to define the number of procedures required by an "average" advanced endoscopy ... Full text Link to item Cite

Inconsistencies in Colonic Tattooing Practice: Differences in Reported and Actual Practices at a Tertiary Medical Center.

Journal Article South Med J · April 2019 OBJECTIVES: Accurate localization of a colonic lesion is crucial to successful resection. Although colonic tattooing is a widely accepted technique to mark lesions for future identification surgery or repeat colonoscopy, no consensus guidelines exist. The ... Full text Open Access Link to item Cite

Competence in Endoscopic Ultrasound and Endoscopic Retrograde Cholangiopancreatography, From Training Through Independent Practice.

Journal Article Gastroenterology · November 2018 BACKGROUND & AIMS: It is unclear whether participation in competency-based fellowship programs for endoscopic ultrasound (EUS) and endoscopic retrograde cholangiopancreatography (ERCP) results in high-quality care in independent practice. We measured quali ... Full text Link to item Cite

Top Ten Tips Palliative Care Clinicians Should Know About Interventional Symptom Management Options When Caring for Patients with Gastrointestinal Malignancies.

Journal Article J Palliat Med · September 2018 Patients diagnosed with advanced stages of gastrointestinal (GI) malignancies are often quite symptomatic, with symptoms primarily related to anatomic sites of obstruction. Endoscopic approaches to the palliation of GI malignancies have begun to overtake s ... Full text Link to item Cite

Mallory–Weiss syndrome

Chapter · January 1, 2016 Gastrointestinal hemorrhage caused by gastroesophageal laceration was first reported by Quincke in 1879; however, the association with retching and vomiting was described by Mallory and Weiss in 1929 (Mallory and Weiss, Am J Med Sci, 178:506-514, 1929; Qui ... Full text Cite

Do larger periprocedural fluid volumes reduce the severity of post-endoscopic retrograde cholangiopancreatography pancreatitis?

Journal Article Pancreas · May 2014 OBJECTIVE: Fluid therapy is a cornerstone of the early treatment of acute pancreatitis (AP), but data are conflicting on whether it affects disease severity. Administering greater fluid volumes (FVs) during induction of experimental AP preserves pancreatic ... Full text Link to item Cite

A combined paging alert and web-based instrument alters clinician behavior and shortens hospital length of stay in acute pancreatitis.

Journal Article Am J Gastroenterol · March 2014 OBJECTIVES: There are many published clinical guidelines for acute pancreatitis (AP). Implementation of these recommendations is variable. We hypothesized that a clinical decision support (CDS) tool would change clinician behavior and shorten hospital leng ... Full text Link to item Cite

Risk models for post-endoscopic retrograde cholangiopancreatography pancreatitis (PEP): smoking and chronic liver disease are predictors of protection against PEP.

Journal Article Pancreas · August 2013 OBJECTIVES: We investigated which variables independently associated with protection against or development of postendoscopic retrograde cholangiopancreatography (ERCP) pancreatitis (PEP) and severity of PEP. Subsequently, we derived predictive risk models ... Full text Link to item Cite

Red cell exchange transfusion for babesiosis in Rhode Island.

Journal Article J Clin Apher · 2009 We report four cases of clinically severe tick borne babesiosis treated with chemotherapy and adjunctive red cell exchange (RCE) at two Rhode Island hospitals from 2004 to 2007. All RCE procedures were performed using a Cobe Spectra device and were well to ... Full text Link to item Cite

Multiple gene segments control the temperature sensitivity and attenuation phenotypes of ca B/Ann Arbor/1/66.

Journal Article J Virol · September 2005 Cold-adapted (ca) B/Ann Arbor/1/66 is the influenza B virus strain master donor virus for FluMist, a live, attenuated, influenza virus vaccine licensed in 2003 in the United States. Each FluMist vaccine strain contains six gene segments of the master donor ... Full text Link to item Cite

The effect of influenza B virus M segment on the replication of reassortant vaccine viruses

Journal Article International Congress Series · June 1, 2004 Flumist™ is a cold-adapted (ca), live attenuated influenza virus vaccine containing H1N1, H3N2, and B strains. The vaccine strains have a 6:2 gene constellation. Six gene segments, PB1, PB2, PA, NP, M and NS, are derived from the master donor viruses, ca A ... Full text Cite

Effects of human metapneumovirus and respiratory syncytial virus antigen insertion in two 3' proximal genome positions of bovine/human parainfluenza virus type 3 on virus replication and immunogenicity.

Journal Article J Virol · October 2003 A live attenuated bovine parainfluenza virus type 3 (PIV3), harboring the fusion (F) and hemagglutinin-neuraminidase (HN) genes of human PIV3, was used as a virus vector to express surface glycoproteins derived from two human pathogens, human metapneumovir ... Full text Link to item Cite