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Joshua Thomas Thaden

Assistant Professor of Medicine
Medicine, Infectious Diseases
DUMC Box 102359, Durham, NC 27710
Rm 201 Alexander H. Sands Buil, 303 Research Drive, Durham, NC 27710

Selected Grants


Characterization of a Novel E. coli Type III Secretion System Associated with Increased Patient Mortality

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2027

Identification of novel pathogen-specific drug targets in gram-negative bacteria (JCVI CDC U54 - Medium Collaborative)

ResearchPrincipal Investigator · Awarded by J. Craig Venter Institute · 2021 - 2024

Duke CTSA (KL2)

ResearchScholar · Awarded by National Institutes of Health · 2018 - 2023

IND-enabling studies of the potent LpxC inhibitor LPC-233 as a novel antibiotic against Gram-negative pathogens

ResearchCo Investigator · Awarded by Valanbio Therapeutics, Inc. · 2020 - 2022

Systems Immunobiology of Antibiotic-Persistent MRSA Infections

ResearchInvestigator · Awarded by The Lundquist Institute · 2016 - 2021

Characterization of a Novel E. coli Type III Secretion System Associated with Increased Patient Mortality

ResearchPrincipal Investigator · Awarded by National Institutes of Health · 2022 - 2027

Identification of novel pathogen-specific drug targets in gram-negative bacteria (JCVI CDC U54 - Medium Collaborative)

ResearchPrincipal Investigator · Awarded by J. Craig Venter Institute · 2021 - 2024

Duke CTSA (KL2)

ResearchScholar · Awarded by National Institutes of Health · 2018 - 2023

IND-enabling studies of the potent LpxC inhibitor LPC-233 as a novel antibiotic against Gram-negative pathogens

ResearchCo Investigator · Awarded by Valanbio Therapeutics, Inc. · 2020 - 2022

Systems Immunobiology of Antibiotic-Persistent MRSA Infections

ResearchInvestigator · Awarded by The Lundquist Institute · 2016 - 2021

Janssen ExPEC Study

ResearchPrincipal Investigator · Awarded by Janssen Research & Development, LLC · 2019 - 2020

External Relationships


  • ESCMID
  • Resonantia Diagnostics, Inc.

This faculty member (or a member of their immediate family) has reported outside activities with the companies, institutions, or organizations listed above. This information is available to institutional leadership and, when appropriate, management plans are in place to address potential conflicts of interest.