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Juhi Jain

Assistant Professor of Pediatrics
Pediatrics, Hematology-Oncology
2301 Erwin Rd, Durham, NC 27710

Selected Publications


Abstract 3339: MRX-2843, a dual MERTK and FLT3 inhibitor, mediates synergistic anti-leukemia activity in combination with BCL-2 inhibitors in acute myeloid leukemia and early T-cell precursor acute lymphoblastic leukemia

Journal Article Cancer Research · June 15, 2022 AbstractWhile overall outcomes have improved for patients with acute leukemia, high-risk subsets including acute myeloid leukemia (AML) and relapsed/refractory early T-cell precursor acute lymphoblastic leuk ... Full text Cite

Burkitt Lymphoma Presenting as a Paraneoplastic Demyelinating Disorder in a Child

Journal Article Journal of Pediatric Neurology · April 2022 AbstractIn adults, lymphomas have been associated with paraneoplastic syndromes that cause cranial nerve palsies, polyneuropathies, and paraplegias. These have been less frequently reported in children. We described a pedia ... Full text Cite

Creating a Collaborative Trauma-Informed Interdisciplinary Citywide Victim Services Model Focused on Health Care for Survivors of Human Trafficking.

Journal Article Public Health Rep · 2022 Although human trafficking is recognized as a public health issue, research on the health effects of human trafficking and best intervention practices is limited. We describe 2 citywide collaborative victim services models, the THRIVE (Trafficking, Healthc ... Full text Link to item Cite

Therapeutic Targeting of Mertk and BCL-2 in T-Cell and Early T-Precursor Acute Lymphoblastic Leukemia

Journal Article Blood · November 5, 2021 AbstractIntroductionT-cell acute lymphoblastic leukemia (T-ALL) accounts for 15% of childhood ALL and is associated with inferior outcomes relative to B-cell ALL. Early T-pre ... Full text Cite

Engineered Cytokines for Cancer and Autoimmune Disease Immunotherapy.

Journal Article Adv Healthc Mater · August 2021 Cytokine signaling is critical to a range of biological processes including cell development, tissue repair, aging, and immunity. In addition to acting as key signal mediators of the immune system, cytokines can also serve as potent immunotherapies with mo ... Full text Link to item Cite

ABSTRACTS

Journal Article Pediatric Blood & Cancer · June 2021 Full text Cite

Use of pegylated interferon in young patients with polycythemia vera and essential thrombocythemia

Journal Article Pediatric Blood & Cancer · March 2021 AbstractMyeloproliferative neoplasms (MPN) are rare disorders in young patients, and because of this, standardized treatment recommendations are not available. Pediatric patients are more frequently treated with hydroxyurea ... Full text Cite

Progress Update in Pediatric Renal Tumors

Journal Article Current Oncology Reports · March 2021 Full text Cite

Raising awareness of human trafficking in key professional fields via a multidisciplinary educational approach

Journal Article International Journal of Human Rights in Healthcare · March 20, 2020 PurposeHuman trafficking (HT) for sex and labor services is among the fastest growing criminal enterprises, causing significant physical and psychological morbidity to victims. ... Full text Cite