Karen Ama-Serwa Chachu

Journal Article Gastroenterology · December 2023 BACKGROUND & AIMS: Biomarkers are used frequently for evaluation and monitoring of patients with Crohn's disease (CD). This American Gastroenterological Association (AGA) guideline is intended to support practitioners in decisions about the use of biomarke ... Full text Link to item Cite

AGA Clinical Practice Guideline on the Role of Biomarkers for the Management of Ulcerative Colitis.

Journal Article Gastroenterology · March 2023 BACKGROUND & AIMS: Biomarkers are used frequently for noninvasive monitoring and treatment decision making in the management of patients with ulcerative colitis (UC). This American Gastroenterological Association (AGA) guideline is intended to support prac ... Full text Link to item Cite

Ustekinumab versus adalimumab for induction and maintenance therapy in biologic-naive patients with moderately to severely active Crohn's disease: a multicentre, randomised, double-blind, parallel-group, phase 3b trial

Journal Article The Lancet · June 2022 Full text Cite

AGA Clinical Practice Guidelines on the Medical Management of Moderate to Severe Luminal and Perianal Fistulizing Crohn's Disease.

Journal Article Gastroenterology · June 2021 Full text Cite

AGA Institute and the Joint Task Force on Allergy-Immunology Practice Parameters Clinical Guidelines for the Management of Eosinophilic Esophagitis.

Journal Article Gastroenterology · May 2020 Full text Open Access Link to item Cite

AGA Clinical Practice Guidelines on the Management of Moderate to Severe Ulcerative Colitis.

Journal Article Gastroenterology · April 2020 Full text Link to item Cite

Improved Long-term Outcomes of Patients With Inflammatory Bowel Disease Receiving Proactive Compared With Reactive Monitoring of Serum Concentrations of Infliximab

Journal Article Clinical Gastroenterology and Hepatology · October 2017 Full text Cite

Immune mechanisms responsible for vaccination against and clearance of mucosal and lymphatic norovirus infection.

Journal Article PLoS Pathog · December 2008 Two cardinal manifestations of viral immunity are efficient clearance of acute infection and the capacity to vaccinate against secondary viral exposure. For noroviruses, the contributions of T cells to viral clearance and vaccination have not been elucidat ... Full text Link to item Cite

Early B-cell activation after West Nile virus infection requires alpha/beta interferon but not antigen receptor signaling.

Journal Article J Virol · November 2008 The B-cell response against West Nile virus (WNV), an encephalitic Flavivirus of global concern, is critical to controlling central nervous system dissemination and neurological sequelae, including death. Here, using a well-characterized mouse model of WNV ... Full text Link to item Cite

Antibody is critical for the clearance of murine norovirus infection.

Journal Article J Virol · July 2008 Human noroviruses cause more than 90% of epidemic nonbacterial gastroenteritis. However, the role of B cells and antibody in the immune response to noroviruses is unclear. Previous studies have demonstrated that human norovirus specific antibody levels inc ... Full text Link to item Cite

Murine noroviruses comprising a single genogroup exhibit biological diversity despite limited sequence divergence.

Journal Article J Virol · October 2007 Viruses within the genus Norovirus of the family Caliciviridae are the major cause of acute, nonbacterial gastroenteritis worldwide. Human noroviruses are genetically diverse, with up to 57% divergence in capsid protein sequences, and comprise three genogr ... Full text Link to item Cite

Genetic composition of the Bacillus subtilis SOS system.

Journal Article J Bacteriol · November 2005 The SOS response in bacteria includes a global transcriptional response to DNA damage. DNA damage is sensed by the highly conserved recombination protein RecA, which facilitates inactivation of the transcriptional repressor LexA. Inactivation of LexA cause ... Full text Link to item Cite